LRRC36

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm-egg recognition (GO:0035036)9.65355543
2multicellular organism reproduction (GO:0032504)9.62289498
3acrosome assembly (GO:0001675)9.36280168
4acrosome reaction (GO:0007340)9.34732861
5cell wall macromolecule catabolic process (GO:0016998)9.14936672
6cell wall macromolecule metabolic process (GO:0044036)9.14936672
7epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.98452750
8binding of sperm to zona pellucida (GO:0007339)8.80861031
9cell-cell recognition (GO:0009988)8.59694918
10regulation of cilium movement (GO:0003352)8.40032300
11spermatid development (GO:0007286)8.34848208
12piRNA metabolic process (GO:0034587)8.20530509
13plasma membrane fusion (GO:0045026)8.09348496
14reproduction (GO:0000003)8.01411846
15male meiosis (GO:0007140)7.50820386
16ventricular system development (GO:0021591)7.47961806
17negative regulation of inclusion body assembly (GO:0090084)6.96827869
18single fertilization (GO:0007338)6.81900309
19synaptonemal complex organization (GO:0070193)6.79912890
20sperm capacitation (GO:0048240)6.31622224
21synaptonemal complex assembly (GO:0007130)6.29354414
22axoneme assembly (GO:0035082)5.95856698
23fertilization (GO:0009566)5.84346208
24behavioral response to nicotine (GO:0035095)5.61835230
25spermatogenesis (GO:0007283)5.59050849
26male gamete generation (GO:0048232)5.56631390
27intraciliary transport (GO:0042073)5.32821735
28male meiosis I (GO:0007141)5.31583215
29regulation of inclusion body assembly (GO:0090083)5.29311278
30regulation of microtubule-based movement (GO:0060632)5.16458695
31gamete generation (GO:0007276)5.15675624
32organic cation transport (GO:0015695)5.05226913
33microtubule severing (GO:0051013)5.04763039
34GTP biosynthetic process (GO:0006183)4.96058057
35DNA methylation involved in gamete generation (GO:0043046)4.91691876
36germ cell development (GO:0007281)4.74603192
37nucleoside diphosphate phosphorylation (GO:0006165)4.72471572
38cellular process involved in reproduction in multicellular organism (GO:0022412)4.67300235
39cilium organization (GO:0044782)4.55297564
40L-fucose catabolic process (GO:0042355)4.50115338
41fucose catabolic process (GO:0019317)4.50115338
42L-fucose metabolic process (GO:0042354)4.50115338
43left/right pattern formation (GO:0060972)4.43392882
44protein localization to cilium (GO:0061512)4.39744097
45UTP biosynthetic process (GO:0006228)4.36524394
46calcium ion-dependent exocytosis (GO:0017156)4.35105874
47cilium assembly (GO:0042384)4.34536781
48meiotic nuclear division (GO:0007126)4.33729524
49chromosome organization involved in meiosis (GO:0070192)4.28590331
50meiotic cell cycle (GO:0051321)4.26089073
51meiosis I (GO:0007127)4.23925393
52DNA deamination (GO:0045006)4.14119299
53multicellular organismal reproductive process (GO:0048609)4.07708444
54left/right axis specification (GO:0070986)4.07249582
55cilium morphogenesis (GO:0060271)4.04911539
56protein polyglutamylation (GO:0018095)3.99221286
57response to pheromone (GO:0019236)3.97938618
58seminiferous tubule development (GO:0072520)3.97845828
59UTP metabolic process (GO:0046051)3.95732529
60cell recognition (GO:0008037)3.89748381
61microtubule-based movement (GO:0007018)3.86482795
62cellular component assembly involved in morphogenesis (GO:0010927)3.83151873
63cellular ketone body metabolic process (GO:0046950)3.79834944
64microtubule depolymerization (GO:0007019)3.78644340
65protein refolding (GO:0042026)3.72341306
66guanosine-containing compound biosynthetic process (GO:1901070)3.64878628
67spermatid nucleus differentiation (GO:0007289)3.59929670
68genitalia morphogenesis (GO:0035112)3.55035126
69negative regulation of telomere maintenance (GO:0032205)3.51611528
70tryptophan catabolic process (GO:0006569)3.50180938
71indole-containing compound catabolic process (GO:0042436)3.50180938
72indolalkylamine catabolic process (GO:0046218)3.50180938
73CTP metabolic process (GO:0046036)3.43795236
74CTP biosynthetic process (GO:0006241)3.43795236
75water-soluble vitamin biosynthetic process (GO:0042364)3.43613501
76indolalkylamine metabolic process (GO:0006586)3.40816541
77kynurenine metabolic process (GO:0070189)3.39481037
78platelet dense granule organization (GO:0060155)3.37429223
79ketone body metabolic process (GO:1902224)3.34459637
80tryptophan metabolic process (GO:0006568)3.17808836
81multicellular organismal development (GO:0007275)3.17422094
82detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.15969037
83gene silencing by RNA (GO:0031047)3.15358876
84centriole assembly (GO:0098534)3.13829458
85detection of light stimulus involved in visual perception (GO:0050908)3.13146342
86detection of light stimulus involved in sensory perception (GO:0050962)3.13146342
87glycerol ether metabolic process (GO:0006662)3.12882700
88pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.10288071
89retinal cone cell development (GO:0046549)3.06862258
90nonmotile primary cilium assembly (GO:0035058)3.02313271
91regulation of spindle checkpoint (GO:0090231)2.96222903
92microtubule bundle formation (GO:0001578)2.96039274
93preassembly of GPI anchor in ER membrane (GO:0016254)2.95185525
94neural tube formation (GO:0001841)2.94591596
95protein complex biogenesis (GO:0070271)2.93524081
96regulation of meiosis I (GO:0060631)2.92744272
97neuronal action potential (GO:0019228)2.92063294
98ether metabolic process (GO:0018904)2.88058343
99nephron tubule morphogenesis (GO:0072078)2.87922251
100nephron epithelium morphogenesis (GO:0072088)2.87922251
101pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.87583943
102DNA packaging (GO:0006323)2.86018652
103pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.85109693
104negative regulation of organelle assembly (GO:1902116)2.84366102
105chromosome condensation (GO:0030261)2.83852364
106exogenous drug catabolic process (GO:0042738)2.83653612
107lactate metabolic process (GO:0006089)2.83203100
108photoreceptor cell maintenance (GO:0045494)2.82817759
109regulation of action potential (GO:0098900)2.81944229
110nucleoside diphosphate metabolic process (GO:0009132)2.81497562
111mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.80692563
112mitochondrial respiratory chain complex I assembly (GO:0032981)2.80692563
113NADH dehydrogenase complex assembly (GO:0010257)2.80692563
114regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.80236138
115centriole replication (GO:0007099)2.76223109
116cell projection assembly (GO:0030031)2.73748025
117negative regulation of mast cell activation (GO:0033004)2.73177548
118regulation of cilium assembly (GO:1902017)2.72932067
119RNA destabilization (GO:0050779)2.72637614
120rRNA catabolic process (GO:0016075)2.72225367
121neurotransmitter metabolic process (GO:0042133)2.71367911
122respiratory chain complex IV assembly (GO:0008535)2.70609323
123sulfation (GO:0051923)2.70292209
124cornea development in camera-type eye (GO:0061303)2.68967253
125mitochondrial respiratory chain complex assembly (GO:0033108)2.68817604
126carnitine transport (GO:0015879)2.67976249
127amino-acid betaine transport (GO:0015838)2.67976249
128carnitine transmembrane transport (GO:1902603)2.66295889
129indole-containing compound metabolic process (GO:0042430)2.66124590
130meiotic cell cycle process (GO:1903046)2.64165527
131kidney morphogenesis (GO:0060993)2.63818274
132reciprocal meiotic recombination (GO:0007131)2.63697988
133reciprocal DNA recombination (GO:0035825)2.63697988
134somite rostral/caudal axis specification (GO:0032525)2.63468674
135synaptic transmission, cholinergic (GO:0007271)2.63239349
136primary amino compound metabolic process (GO:1901160)2.63039355
137gamma-aminobutyric acid transport (GO:0015812)2.62245439
138regulation of glucokinase activity (GO:0033131)2.61700936
139regulation of hexokinase activity (GO:1903299)2.61700936
140regulation of mesoderm development (GO:2000380)2.61677393
141negative regulation of cytosolic calcium ion concentration (GO:0051481)2.59754329
142G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.58465412
143positive regulation of defense response to virus by host (GO:0002230)2.58031559
144regulation of neurotransmitter uptake (GO:0051580)2.57792121
145monoubiquitinated protein deubiquitination (GO:0035520)2.55812149
146drug catabolic process (GO:0042737)2.55168715
147auditory receptor cell stereocilium organization (GO:0060088)2.53034765
148spinal cord motor neuron differentiation (GO:0021522)2.52642343
149synapsis (GO:0007129)2.51628371
150pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.51167654
151ubiquinone biosynthetic process (GO:0006744)2.51149188
152phosphatidylinositol acyl-chain remodeling (GO:0036149)2.50690894
153positive regulation of meiosis (GO:0045836)2.50345459
154GPI anchor metabolic process (GO:0006505)2.49933512
155amine catabolic process (GO:0009310)2.49216581
156cellular biogenic amine catabolic process (GO:0042402)2.49216581
157photoreceptor cell development (GO:0042461)2.47808654
158peptidyl-glutamic acid modification (GO:0018200)2.47773851
159cytochrome complex assembly (GO:0017004)2.47442857
160reflex (GO:0060004)2.46960158
161organelle assembly (GO:0070925)2.46909373
162benzene-containing compound metabolic process (GO:0042537)2.46474937
163S-adenosylmethionine metabolic process (GO:0046500)2.45769592
164regulation of protein polyubiquitination (GO:1902914)2.45355410
165fucosylation (GO:0036065)2.43135951
166behavioral response to ethanol (GO:0048149)2.42912983
167alanine transport (GO:0032328)2.42777243
168regulation of rhodopsin mediated signaling pathway (GO:0022400)2.42329147
169cytidine metabolic process (GO:0046087)2.42087072
170cytidine catabolic process (GO:0006216)2.42087072
171cytidine deamination (GO:0009972)2.42087072
172cilium or flagellum-dependent cell motility (GO:0001539)14.0504691
173axonemal dynein complex assembly (GO:0070286)12.8807103
174cilium movement (GO:0003341)11.4717079
175sperm motility (GO:0030317)11.4239050
176epithelial cilium movement (GO:0003351)10.9283860
177fusion of sperm to egg plasma membrane (GO:0007342)10.6688301
178motile cilium assembly (GO:0044458)10.1752916

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.62226463
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.90768950
3EZH2_22144423_ChIP-Seq_EOC_Human4.18070423
4PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse3.18730147
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.03555629
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.70897015
7GBX2_23144817_ChIP-Seq_PC3_Human2.68839259
8IGF1R_20145208_ChIP-Seq_DFB_Human2.51736226
9CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.49000447
10POU3F2_20337985_ChIP-ChIP_501MEL_Human2.15245982
11CTBP1_25329375_ChIP-Seq_LNCAP_Human2.08043833
12FUS_26573619_Chip-Seq_HEK293_Human2.07759006
13CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.07048031
14GATA1_26923725_Chip-Seq_HPCs_Mouse2.03667042
15EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.00311018
16FLI1_27457419_Chip-Seq_LIVER_Mouse1.97780451
17P300_19829295_ChIP-Seq_ESCs_Human1.92341301
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.90585490
19VDR_22108803_ChIP-Seq_LS180_Human1.88032364
20ER_23166858_ChIP-Seq_MCF-7_Human1.85170164
21WDR5_24793694_ChIP-Seq_LNCAP_Human1.83030158
22TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.80302881
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.79907515
24EWS_26573619_Chip-Seq_HEK293_Human1.79304374
25PCGF2_27294783_Chip-Seq_ESCs_Mouse1.77851219
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.75937964
27ZNF274_21170338_ChIP-Seq_K562_Hela1.69851119
28TAF15_26573619_Chip-Seq_HEK293_Human1.66057574
29SOX2_22085726_ChIP-Seq_NPCs_Mouse1.63804292
30RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.63165422
31CBP_20019798_ChIP-Seq_JUKART_Human1.61381018
32IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.61381018
33ELK4_26923725_Chip-Seq_MESODERM_Mouse1.61130680
34TP53_22573176_ChIP-Seq_HFKS_Human1.57133057
35TAL1_26923725_Chip-Seq_HPCs_Mouse1.56934202
36KAP1_22055183_ChIP-Seq_ESCs_Mouse1.56338859
37SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.55103033
38BCAT_22108803_ChIP-Seq_LS180_Human1.54675418
39IRF1_19129219_ChIP-ChIP_H3396_Human1.54167869
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.53929540
41ERG_20517297_ChIP-Seq_VCAP_Human1.51665196
42AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.51040263
43AR_25329375_ChIP-Seq_VCAP_Human1.49724668
44SALL1_21062744_ChIP-ChIP_HESCs_Human1.48869012
45* SOX2_19829295_ChIP-Seq_ESCs_Human1.48541713
46* NANOG_19829295_ChIP-Seq_ESCs_Human1.48541713
47STAT1_17558387_ChIP-Seq_HELA_Human1.46521103
48UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.46154631
49STAT3_23295773_ChIP-Seq_U87_Human1.45891560
50SMAD4_21799915_ChIP-Seq_A2780_Human1.45769505
51PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.45718361
52FLI1_21867929_ChIP-Seq_TH2_Mouse1.44296021
53MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.43546376
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.43342363
55NR3C1_21868756_ChIP-Seq_MCF10A_Human1.41109335
56ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.39675971
57GATA3_21878914_ChIP-Seq_MCF-7_Human1.37858833
58GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37481450
59KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.36749109
60GATA3_21867929_ChIP-Seq_CD8_Mouse1.36271738
61GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.35906889
62ETV2_25802403_ChIP-Seq_MESCs_Mouse1.35145044
63PCGF2_27294783_Chip-Seq_NPCs_Mouse1.34946569
64TCF4_23295773_ChIP-Seq_U87_Human1.34681456
65NFE2_27457419_Chip-Seq_LIVER_Mouse1.34174711
66FOXA1_21572438_ChIP-Seq_LNCaP_Human1.33492169
67TCF4_22108803_ChIP-Seq_LS180_Human1.31439832
68MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.31417181
69CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.31273749
70SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30235910
71DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.30097670
72P53_21459846_ChIP-Seq_SAOS-2_Human1.30095707
73KDM2B_26808549_Chip-Seq_REH_Human1.28833138
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.27939339
75GF1_26923725_Chip-Seq_HPCs_Mouse1.27781157
76PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.27263409
77AR_20517297_ChIP-Seq_VCAP_Human1.27075149
78NCOR_22424771_ChIP-Seq_293T_Human1.27028035
79GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.26002437
80SUZ12_27294783_Chip-Seq_NPCs_Mouse1.25995197
81TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.25198342
82TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24994914
83TOP2B_26459242_ChIP-Seq_MCF-7_Human1.24130040
84* RUNX2_22187159_ChIP-Seq_PCA_Human1.23930999
85EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.23837997
86CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.23663729
87SMAD3_21741376_ChIP-Seq_EPCs_Human1.23093038
88REST_21632747_ChIP-Seq_MESCs_Mouse1.22877989
89MYC_18940864_ChIP-ChIP_HL60_Human1.21976419
90KLF5_20875108_ChIP-Seq_MESCs_Mouse1.21965724
91CBX2_27304074_Chip-Seq_ESCs_Mouse1.21777110
92MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21036564
93SMAD4_21741376_ChIP-Seq_EPCs_Human1.21013329
94RNF2_27304074_Chip-Seq_NSC_Mouse1.20971901
95CTBP2_25329375_ChIP-Seq_LNCAP_Human1.19058217
96RUNX1_26923725_Chip-Seq_HPCs_Mouse1.19030347
97SPI1_26923725_Chip-Seq_HPCs_Mouse1.18656450
98HOXB7_26014856_ChIP-Seq_BT474_Human1.18504511
99LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.18499662
100GABP_17652178_ChIP-ChIP_JURKAT_Human1.17629458
101RBPJ_22232070_ChIP-Seq_NCS_Mouse1.16965169
102* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16305395
103PRDM14_20953172_ChIP-Seq_ESCs_Human1.15586641
104SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.15363126
105CRX_20693478_ChIP-Seq_RETINA_Mouse1.14258090
106NANOG_18555785_Chip-Seq_ESCs_Mouse1.12988945
107AR_21572438_ChIP-Seq_LNCaP_Human1.12957057
108EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.10459939
109FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09446483
110RAD21_21589869_ChIP-Seq_MESCs_Mouse1.08845431
111FOXA1_27270436_Chip-Seq_PROSTATE_Human1.08597605
112FOXA1_25329375_ChIP-Seq_VCAP_Human1.08597605
113PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.08560822
114YY1_22570637_ChIP-Seq_MALME-3M_Human1.08184052
115MYC_19829295_ChIP-Seq_ESCs_Human1.07976021
116PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.07489633
117AUTS2_25519132_ChIP-Seq_293T-REX_Human1.07207387
118ESET_19884257_ChIP-Seq_ESCs_Mouse1.07101499
119P53_22387025_ChIP-Seq_ESCs_Mouse1.06936943
120EZH2_27294783_Chip-Seq_NPCs_Mouse1.05959748
121* NANOG_20526341_ChIP-Seq_ESCs_Human1.04809201
122EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04733705
123* TAF2_19829295_ChIP-Seq_ESCs_Human1.04106438
124CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03419620
125GF1B_26923725_Chip-Seq_HPCs_Mouse1.03244905
126OCT4_18555785_Chip-Seq_ESCs_Mouse1.02819738
127GATA3_21867929_ChIP-Seq_TH1_Mouse1.02780633
128ERA_21632823_ChIP-Seq_H3396_Human1.02714283
129CDX2_22108803_ChIP-Seq_LS180_Human1.02441155
130FOXH1_21741376_ChIP-Seq_EPCs_Human1.00376961
131STAT3_18555785_Chip-Seq_ESCs_Mouse1.00081987
132OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99496834
133ETV1_20927104_ChIP-Seq_GIST48_Human0.98731527
134OCT4_21477851_ChIP-Seq_ESCs_Mouse0.98363374
135SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.98035309
136NFYB_21822215_ChIP-Seq_K562_Human0.97998611
137SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97635026
138TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97383722
139TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.97271879
140ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.96380726
141EGR1_23403033_ChIP-Seq_LIVER_Mouse0.96147049
142CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.96005753
143ZFP57_27257070_Chip-Seq_ESCs_Mouse0.95748729
144CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95673070
145PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95665012
146TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94656065
147POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94656065
148KLF4_18555785_Chip-Seq_ESCs_Mouse0.94521838
149MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.94412589
150CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.93839000
151ESRRB_18555785_Chip-Seq_ESCs_Mouse0.93716190
152SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93615857
153GATA1_19941827_ChIP-Seq_MEL86_Mouse0.92718749
154P300_18555785_Chip-Seq_ESCs_Mouse0.92322043
155NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.91870863
156CMYC_18555785_Chip-Seq_ESCs_Mouse0.91685763
157LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.91000031
158SUZ12_18555785_Chip-Seq_ESCs_Mouse0.90694341
159ELF1_20517297_ChIP-Seq_JURKAT_Human0.89469913
160PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.89102703
161TBL1_22424771_ChIP-Seq_293T_Human0.88860993
162SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87658800

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.39848196
2MP0001929_abnormal_gametogenesis5.10822716
3MP0008877_abnormal_DNA_methylation3.75176229
4MP0002653_abnormal_ependyma_morphology3.65290760
5MP0002210_abnormal_sex_determination3.42081571
6MP0005670_abnormal_white_adipose3.08625082
7MP0002161_abnormal_fertility/fecundity2.93388593
8MP0001145_abnormal_male_reproductive2.88244358
9MP0000653_abnormal_sex_gland2.63413105
10MP0005551_abnormal_eye_electrophysiolog2.41223941
11MP0010386_abnormal_urinary_bladder2.31195778
12MP0008875_abnormal_xenobiotic_pharmacok2.25484802
13MP0002160_abnormal_reproductive_system2.16632998
14MP0002876_abnormal_thyroid_physiology2.15138722
15MP0001968_abnormal_touch/_nociception2.12842008
16MP0003787_abnormal_imprinting2.11694064
17MP0002102_abnormal_ear_morphology2.01935906
18MP0005646_abnormal_pituitary_gland2.00061986
19MP0005410_abnormal_fertilization13.3794452
20MP0004885_abnormal_endolymph1.96037268
21MP0000013_abnormal_adipose_tissue1.93684307
22MP0000569_abnormal_digit_pigmentation1.89089829
23MP0001501_abnormal_sleep_pattern1.87805552
24MP0008872_abnormal_physiological_respon1.83533871
25MP0009745_abnormal_behavioral_response1.77231916
26MP0001485_abnormal_pinna_reflex1.70670101
27MP0003646_muscle_fatigue1.68794936
28MP0003011_delayed_dark_adaptation1.66007966
29MP0006292_abnormal_olfactory_placode1.62045469
30MP0005623_abnormal_meninges_morphology1.61664993
31MP0002928_abnormal_bile_duct1.60898592
32MP0002272_abnormal_nervous_system1.56809952
33MP0002693_abnormal_pancreas_physiology1.55619102
34MP0004142_abnormal_muscle_tone1.54071181
35MP0008004_abnormal_stomach_pH1.53800086
36MP0002938_white_spotting1.53367209
37MP0004147_increased_porphyrin_level1.52067787
38MP0000427_abnormal_hair_cycle1.51609602
39MP0004043_abnormal_pH_regulation1.49887379
40MP0006276_abnormal_autonomic_nervous1.48672036
41MP0005174_abnormal_tail_pigmentation1.45981114
42MP0001486_abnormal_startle_reflex1.43946632
43MP0005084_abnormal_gallbladder_morpholo1.43432649
44MP0003880_abnormal_central_pattern1.43243369
45MP0001765_abnormal_ion_homeostasis1.41646854
46MP0002163_abnormal_gland_morphology1.41563845
47MP0003878_abnormal_ear_physiology1.39410188
48MP0005377_hearing/vestibular/ear_phenot1.39410188
49MP0002736_abnormal_nociception_after1.39188934
50MP0003183_abnormal_peptide_metabolism1.39111074
51MP0005389_reproductive_system_phenotype1.38889787
52MP0003283_abnormal_digestive_organ1.38239550
53MP0001986_abnormal_taste_sensitivity1.37537319
54MP0005167_abnormal_blood-brain_barrier1.37303806
55MP0002877_abnormal_melanocyte_morpholog1.36296111
56MP0002733_abnormal_thermal_nociception1.35600244
57MP0008058_abnormal_DNA_repair1.34933296
58MP0001944_abnormal_pancreas_morphology1.29451367
59MP0001970_abnormal_pain_threshold1.28593589
60MP0005085_abnormal_gallbladder_physiolo1.28569157
61MP0003943_abnormal_hepatobiliary_system1.25209950
62MP0004133_heterotaxia1.21773689
63MP0002572_abnormal_emotion/affect_behav1.21397176
64MP0005379_endocrine/exocrine_gland_phen1.19604580
65MP0004742_abnormal_vestibular_system1.18333348
66MP0005647_abnormal_sex_gland1.17945439
67MP0001905_abnormal_dopamine_level1.15074521
68MP0002064_seizures1.14567028
69MP0000372_irregular_coat_pigmentation1.13290724
70MP0005365_abnormal_bile_salt1.11356922
71MP0002735_abnormal_chemical_nociception1.05916163
72MP0002254_reproductive_system_inflammat1.05767986
73MP0002277_abnormal_respiratory_mucosa1.05690884
74MP0002234_abnormal_pharynx_morphology1.05187742
75MP0005332_abnormal_amino_acid1.03875345
76MP0002909_abnormal_adrenal_gland1.00798976
77MP0004233_abnormal_muscle_weight0.99546430
78MP0000383_abnormal_hair_follicle0.99053336
79MP0000678_abnormal_parathyroid_gland0.98850028
80MP0005645_abnormal_hypothalamus_physiol0.97713370
81MP0004924_abnormal_behavior0.97378581
82MP0005386_behavior/neurological_phenoty0.97378581
83MP0003252_abnormal_bile_duct0.96875743
84MP0002282_abnormal_trachea_morphology0.96536580
85MP0002067_abnormal_sensory_capabilities0.96045841
86MP0001529_abnormal_vocalization0.95711731
87MP0010329_abnormal_lipoprotein_level0.95285917
88MP0002138_abnormal_hepatobiliary_system0.94864214
89MP0003718_maternal_effect0.93275551
90MP0002132_abnormal_respiratory_system0.92996108
91MP0000230_abnormal_systemic_arterial0.90863878
92MP0003172_abnormal_lysosome_physiology0.90711529
93MP0005195_abnormal_posterior_eye0.89003872
94MP0002734_abnormal_mechanical_nocicepti0.88923964
95MP0004215_abnormal_myocardial_fiber0.88528900
96MP0001963_abnormal_hearing_physiology0.87904679
97MP0002095_abnormal_skin_pigmentation0.87811883
98MP0003137_abnormal_impulse_conducting0.87551242
99MP0005636_abnormal_mineral_homeostasis0.86994062
100MP0002063_abnormal_learning/memory/cond0.86772733
101MP0000026_abnormal_inner_ear0.85508089
102MP0003122_maternal_imprinting0.85460505
103MP0002229_neurodegeneration0.84092852
104MP0009046_muscle_twitch0.82876737
105MP0008995_early_reproductive_senescence0.81561207
106MP0003959_abnormal_lean_body0.81521199
107MP0008775_abnormal_heart_ventricle0.81137456
108MP0008057_abnormal_DNA_replication0.78763950
109MP0004264_abnormal_extraembryonic_tissu0.75003084
110MP0005220_abnormal_exocrine_pancreas0.74657713
111MP0003136_yellow_coat_color0.74331462
112MP0002078_abnormal_glucose_homeostasis0.74174011
113MP0003699_abnormal_female_reproductive0.72497197
114MP0006072_abnormal_retinal_apoptosis0.71721095
115MP0003045_fibrosis0.70469845
116MP0004808_abnormal_hematopoietic_stem0.69803335
117MP0009780_abnormal_chondrocyte_physiolo0.67455560
118MP0003953_abnormal_hormone_level0.66894485
119MP0008961_abnormal_basal_metabolism0.66693039
120MP0001984_abnormal_olfaction0.66177537
121MP0002638_abnormal_pupillary_reflex0.65033379
122MP0001764_abnormal_homeostasis0.61854605
123MP0006054_spinal_hemorrhage0.60207624
124MP0002837_dystrophic_cardiac_calcinosis0.58788237
125MP0001851_eye_inflammation0.57523849
126MP0000003_abnormal_adipose_tissue0.56294785
127MP0000358_abnormal_cell_content/0.55958743
128MP0002971_abnormal_brown_adipose0.54550685
129MP0003195_calcinosis0.53011683
130MP0001119_abnormal_female_reproductive0.51780655
131MP0001849_ear_inflammation0.50436659
132MP0002970_abnormal_white_adipose0.47905410
133MP0009115_abnormal_fat_cell0.47212470
134MP0000613_abnormal_salivary_gland0.46747551
135MP0005666_abnormal_adipose_tissue0.46546217
136MP0002295_abnormal_pulmonary_circulatio0.46222759
137MP0008007_abnormal_cellular_replicative0.46113610
138MP0005253_abnormal_eye_physiology0.45963682
139MP0003633_abnormal_nervous_system0.45206756
140MP0009697_abnormal_copulation0.44861564
141MP0002168_other_aberrant_phenotype0.44698102
142MP0001324_abnormal_eye_pigmentation0.43009994
143MP0004145_abnormal_muscle_electrophysio0.42902571
144MP0000631_abnormal_neuroendocrine_gland0.42388244
145MP0010094_abnormal_chromosome_stability0.41608514
146MP0003115_abnormal_respiratory_system0.41449668
147MP0002405_respiratory_system_inflammati0.39976748
148MP0001502_abnormal_circadian_rhythm0.39526170
149MP0005375_adipose_tissue_phenotype0.38352064
150MP0005535_abnormal_body_temperature0.38132427
151MP0001270_distended_abdomen0.36686348
152MP0005334_abnormal_fat_pad0.35848008
153MP0006036_abnormal_mitochondrial_physio0.35364547
154MP0005075_abnormal_melanosome_morpholog0.35314232
155MP0004270_analgesia0.34909498
156MP0001661_extended_life_span0.34572298
157MP0004782_abnormal_surfactant_physiolog0.34057261
158MP0003879_abnormal_hair_cell0.33161164
159MP0001919_abnormal_reproductive_system0.33106425
160MP0000538_abnormal_urinary_bladder0.31152690
161MP0003942_abnormal_urinary_system0.29657062
162MP0010307_abnormal_tumor_latency0.29320956
163MP0002557_abnormal_social/conspecific_i0.28913064

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)9.05597634
2Rhinitis (HP:0012384)8.68431984
3Abnormal respiratory motile cilium morphology (HP:0005938)8.64332321
4Abnormal respiratory epithelium morphology (HP:0012253)8.64332321
5Chronic bronchitis (HP:0004469)8.18191184
6Nasal polyposis (HP:0100582)6.28366916
7Infertility (HP:0000789)5.91707396
8Bronchiectasis (HP:0002110)5.45390122
9Abnormality of the nasal mucosa (HP:0000433)5.25359877
10Bronchitis (HP:0012387)4.84587749
11Male infertility (HP:0003251)4.68813950
12Nephronophthisis (HP:0000090)4.27324355
13Abnormality of midbrain morphology (HP:0002418)3.93421649
14Molar tooth sign on MRI (HP:0002419)3.93421649
15Congenital stationary night blindness (HP:0007642)3.62182546
16Type II lissencephaly (HP:0007260)3.32304429
17Pancreatic fibrosis (HP:0100732)3.28118510
18Abnormality of the renal medulla (HP:0100957)3.25659242
19Tubulointerstitial nephritis (HP:0001970)3.08482801
20Medial flaring of the eyebrow (HP:0010747)3.07078959
21Recurrent sinusitis (HP:0011108)2.98971181
22Abnormal rod and cone electroretinograms (HP:0008323)2.98836313
23Recurrent otitis media (HP:0000403)2.98427968
24True hermaphroditism (HP:0010459)2.95399537
25Attenuation of retinal blood vessels (HP:0007843)2.83880147
26Cystic liver disease (HP:0006706)2.73084022
27Occipital encephalocele (HP:0002085)2.67835126
28Large for gestational age (HP:0001520)2.65615809
29Abolished electroretinogram (ERG) (HP:0000550)2.64284252
30Postaxial foot polydactyly (HP:0001830)2.63754817
31Recurrent bronchitis (HP:0002837)2.62185458
32Congenital, generalized hypertrichosis (HP:0004540)2.61262104
33Tubular atrophy (HP:0000092)2.58560032
34Hyperalaninemia (HP:0003348)2.57798492
35Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.57798492
36Abnormality of alanine metabolism (HP:0010916)2.57798492
37Decreased circulating renin level (HP:0003351)2.54394384
38Bile duct proliferation (HP:0001408)2.48478704
39Abnormal biliary tract physiology (HP:0012439)2.48478704
40Absent rod-and cone-mediated responses on ERG (HP:0007688)2.47757935
41Hyperventilation (HP:0002883)2.42436565
42Congenital hepatic fibrosis (HP:0002612)2.42386545
43Inability to walk (HP:0002540)2.41055846
44Renal cortical cysts (HP:0000803)2.40247713
45Pancreatic cysts (HP:0001737)2.38783093
46Cerebellar dysplasia (HP:0007033)2.37557057
47Tubulointerstitial abnormality (HP:0001969)2.33521430
48Pendular nystagmus (HP:0012043)2.31278539
493-Methylglutaconic aciduria (HP:0003535)2.29549945
50Abnormal spermatogenesis (HP:0008669)2.29112699
51Decreased central vision (HP:0007663)2.27958277
52Progressive inability to walk (HP:0002505)2.26798785
53Lissencephaly (HP:0001339)2.25039934
54Tachypnea (HP:0002789)2.22960441
55Chronic sinusitis (HP:0011109)2.21566836
56Congenital primary aphakia (HP:0007707)2.14247786
57Aplasia/Hypoplasia of the tongue (HP:0010295)2.13323942
58Gaze-evoked nystagmus (HP:0000640)2.12411237
59Increased corneal curvature (HP:0100692)2.11856719
60Keratoconus (HP:0000563)2.11856719
61Gait imbalance (HP:0002141)2.10924857
62Progressive cerebellar ataxia (HP:0002073)2.06410805
63Median cleft lip (HP:0000161)2.05824855
64Hypoplasia of the fovea (HP:0007750)2.05498700
65Aplasia/Hypoplasia of the fovea (HP:0008060)2.05498700
66Decreased electroretinogram (ERG) amplitude (HP:0000654)2.05233199
67Hypothermia (HP:0002045)2.03908789
68Bony spicule pigmentary retinopathy (HP:0007737)2.03553278
69Abnormal drinking behavior (HP:0030082)2.03465450
70Polydipsia (HP:0001959)2.03465450
71Abnormality of the renal cortex (HP:0011035)2.00719939
72Mitochondrial inheritance (HP:0001427)2.00678717
73Hemiparesis (HP:0001269)2.00142498
74Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.2625931
75Dynein arm defect of respiratory motile cilia (HP:0012255)10.8419509
76Absent/shortened dynein arms (HP:0200106)10.8419509
77Abnormal respiratory motile cilium physiology (HP:0012261)10.5172246
78Oculomotor apraxia (HP:0000657)1.97091685
79Stage 5 chronic kidney disease (HP:0003774)1.95511104
80Aplasia/Hypoplasia of the tibia (HP:0005772)1.95055867
81Facial cleft (HP:0002006)1.94777850
82Fibular hypoplasia (HP:0003038)1.94508790
83Abnormality of dentin (HP:0010299)1.94390991
84Bilateral microphthalmos (HP:0007633)1.93069530
85Methylmalonic acidemia (HP:0002912)1.92154626
86Increased CSF lactate (HP:0002490)1.90926429
87Acute necrotizing encephalopathy (HP:0006965)1.90293038
88Ketoacidosis (HP:0001993)1.89385261
89Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.88445798
90Nephrogenic diabetes insipidus (HP:0009806)1.85187815
91Ketosis (HP:0001946)1.84941592
92Lipid accumulation in hepatocytes (HP:0006561)1.82600751
93Optic disc pallor (HP:0000543)1.80968553
94Intestinal atresia (HP:0011100)1.80505371
95Genetic anticipation (HP:0003743)1.80266805
96Supernumerary spleens (HP:0009799)1.80249870
97Postaxial hand polydactyly (HP:0001162)1.79710047
98Agitation (HP:0000713)1.78449282
99Concave nail (HP:0001598)1.77738606
100Abnormality of the pons (HP:0007361)1.77605466
101Tubulointerstitial fibrosis (HP:0005576)1.76804381
102Abnormality of permanent molar morphology (HP:0011071)1.75828049
103Abnormality of the dental root (HP:0006486)1.75828049
104Taurodontia (HP:0000679)1.75828049
105Constricted visual fields (HP:0001133)1.75111039
106Abnormality of renin-angiotensin system (HP:0000847)1.74429921
107Broad-based gait (HP:0002136)1.70666519
108Acute encephalopathy (HP:0006846)1.70492595
109Progressive macrocephaly (HP:0004481)1.69573608
110Nephropathy (HP:0000112)1.68824884
111Male pseudohermaphroditism (HP:0000037)1.67988900
112Hyperkalemia (HP:0002153)1.64079332
113Abnormality of the dental pulp (HP:0006479)1.63857717
114Renal dysplasia (HP:0000110)1.63073040
115Chronic hepatic failure (HP:0100626)1.62998509
116Abnormality of molar morphology (HP:0011070)1.62361342
117Abnormality of molar (HP:0011077)1.62361342
118Aplasia/Hypoplasia of the lens (HP:0008063)1.62274178
119Hyperinsulinemic hypoglycemia (HP:0000825)1.61653875
120Genital tract atresia (HP:0001827)1.60039652
121Gonadotropin excess (HP:0000837)1.58617475
122Broad distal phalanx of finger (HP:0009836)1.54640575
123Bell-shaped thorax (HP:0001591)1.54410122
124Anencephaly (HP:0002323)1.53892612
125Azoospermia (HP:0000027)1.52647811
126Retinal atrophy (HP:0001105)1.50425407
127Short thorax (HP:0010306)1.49993691
128Vaginal atresia (HP:0000148)1.49983430
129Poor coordination (HP:0002370)1.45051340
130Abnormality of renal excretion (HP:0011036)1.44065649
131Short ribs (HP:0000773)1.39283297
132Abnormality of the lower motor neuron (HP:0002366)1.38450066
133J-shaped sella turcica (HP:0002680)1.37812892
134Impulsivity (HP:0100710)1.36712009
135Short nail (HP:0001799)1.31349859
136Sclerocornea (HP:0000647)1.31222040
137Abnormal urine output (HP:0012590)1.30437129
138Preaxial hand polydactyly (HP:0001177)1.30127185
139Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.29708186
14011 pairs of ribs (HP:0000878)1.29499853
141Bifid tongue (HP:0010297)1.28612831
142Retinal dysplasia (HP:0007973)1.26529573
143Polycystic kidney dysplasia (HP:0000113)1.25635401
144Polyuria (HP:0000103)1.25536567
145Easy fatigability (HP:0003388)1.24887995
146Insulin-resistant diabetes mellitus (HP:0000831)1.24034219
147Hypoplasia of the capital femoral epiphysis (HP:0003090)1.20681746
148Cholecystitis (HP:0001082)1.20125080
149Abnormal gallbladder physiology (HP:0012438)1.20125080
150Furrowed tongue (HP:0000221)1.17946505
151Absent frontal sinuses (HP:0002688)1.14636889
152Degeneration of anterior horn cells (HP:0002398)1.12018222
153Abnormality of the anterior horn cell (HP:0006802)1.12018222

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK46.65633066
2PDK36.65633066
3PRKD35.26895917
4TESK14.97908575
5FRK4.89140025
6PDK24.47251583
7MAPK154.11138660
8PNCK3.95684872
9ICK3.70161557
10ADRBK23.33356820
11MAP4K23.14689072
12TLK13.00795871
13WNK42.84416180
14ZAK2.56989968
15NUAK12.28620052
16PTK2B2.10887720
17MUSK2.01344953
18TXK1.89674049
19OXSR11.88297417
20CASK1.80116189
21DAPK21.75804901
22MAPK131.66215473
23PINK11.65547651
24PASK1.60893482
25MAPKAPK51.57671339
26NEK21.52128504
27CAMKK21.51672156
28MAP3K41.50911410
29EEF2K1.49720614
30STK391.40705214
31TAOK31.23857215
32CAMK1G1.19699881
33CDC71.18400404
34MST41.18272957
35STK381.11255918
36ADRBK11.08037885
37PAK31.06904613
38BCKDK1.01073802
39PIK3CA0.99368347
40DYRK1B0.96464761
41PRKCE0.95975040
42WNK10.95647876
43PHKG10.93395808
44PHKG20.93395808
45TGFBR10.91758232
46BMPR1B0.91126030
47TAF10.90989409
48DYRK20.89126593
49VRK20.88991449
50IRAK10.87288295
51PLK20.87212716
52ARAF0.82961771
53WEE10.82682525
54NTRK30.82100281
55DYRK30.81849418
56CSNK1G20.81764721
57CSNK1G30.79380655
58CSNK1G10.79370374
59NEK60.78945064
60BMPR20.78403619
61MAPKAPK30.75973842
62MAP2K60.75102867
63MKNK20.74242638
64PDK10.73727975
65INSRR0.72895084
66BRAF0.72650219
67TRIM280.72123904
68CSNK1A1L0.68161184
69KIT0.63653934
70PRKCQ0.62168861
71MARK10.62085058
72BRSK20.58632962
73IKBKB0.58285838
74FGFR20.58114667
75MAP2K70.57471798
76RPS6KA50.57339007
77STK110.56868623
78PRKCI0.56175490
79CDK190.54632466
80NME10.51087976
81GRK70.50652707
82GRK10.50191863
83RPS6KA60.49980149
84BCR0.49506899
85CAMK2A0.49153277
86ITK0.48671198
87VRK10.48290332
88RPS6KA20.48133537
89CAMK10.45994687
90ERBB20.45190464
91NLK0.44549044
92WNK30.44367225
93HIPK20.43909897
94MAP3K120.43674486
95TTK0.43429834
96CHEK20.41228291
97PRKCA0.40613825
98STK160.40449336
99LIMK10.40048368
100TNK20.39670367
101PLK40.39152603
102EPHA40.38983215
103RPS6KB10.38099294
104LMTK20.36234663
105STK30.35487192
106CSNK1A10.35232820
107CDK30.34899698
108PKN10.34033477
109CHUK0.33999949
110MAP3K20.33823963
111GRK50.33107525
112MAP3K70.32815873
113CSNK1D0.32775347
114CCNB10.32566409
115SIK20.32505760
116PDPK10.32093892
117CDC42BPA0.31213346
118PRKAA20.30647192
119PRKAA10.30509744
120PRKCZ0.29410992
121ERBB30.29085447
122PIM20.28935759
123ATM0.27581107
124PRKCG0.26022641
125ZAP700.25240833
126NTRK10.25060789
127ATR0.24080175
128MTOR0.23827311
129MAP3K10.22620540
130NTRK20.22204271
131TGFBR20.20908451
132STK100.19275595
133EPHB10.18819095
134CHEK10.18784162
135PRKD20.18762343
136PRKCH0.18319656
137IRAK20.16343485
138RPS6KA10.15887450
139TYRO30.15834644
140MAP2K20.14629947
141EPHA30.14519673
142TBK10.13219673
143PTK60.12739274
144MOS0.12183733
145GSK3A0.12092373
146PRKG20.11493995
147BRSK10.11116886
148PAK10.09875568
149TIE10.09590448
150CDK90.09440437
151STK38L0.09148591
152TEC0.08467547
153ACVR1B0.08360872
154TNIK0.08177656
155PIK3CG0.07678194
156PRKG10.07514522
157CSNK2A10.06401043
158MAPK10.05899398
159RPS6KC10.05509871
160RPS6KL10.05509871
161MAPK80.05026052
162AURKA0.04566187
163PRKACA0.04408037

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007503.77598385
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.67204156
3Protein processing in endoplasmic reticulum_Homo sapiens_hsa041413.19379523
4Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.86106700
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.80632896
6Linoleic acid metabolism_Homo sapiens_hsa005912.76366989
7Pyruvate metabolism_Homo sapiens_hsa006202.74257061
8Phototransduction_Homo sapiens_hsa047442.62974655
9Basal transcription factors_Homo sapiens_hsa030222.62973297
10Fatty acid biosynthesis_Homo sapiens_hsa000612.54695316
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.52055575
12Glycosaminoglycan degradation_Homo sapiens_hsa005312.51280030
13Butanoate metabolism_Homo sapiens_hsa006502.44812934
14Glucagon signaling pathway_Homo sapiens_hsa049222.43431925
15Oxidative phosphorylation_Homo sapiens_hsa001902.40340843
16Propanoate metabolism_Homo sapiens_hsa006402.27222042
17Nitrogen metabolism_Homo sapiens_hsa009102.25762612
18Protein export_Homo sapiens_hsa030602.15429008
19Dorso-ventral axis formation_Homo sapiens_hsa043202.12256368
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.10162172
21Carbohydrate digestion and absorption_Homo sapiens_hsa049732.09767720
22Insulin secretion_Homo sapiens_hsa049112.00177352
23Caffeine metabolism_Homo sapiens_hsa002321.97603219
24Huntingtons disease_Homo sapiens_hsa050161.91566564
25Tryptophan metabolism_Homo sapiens_hsa003801.89892494
26Nicotine addiction_Homo sapiens_hsa050331.85077682
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.81151210
28Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.78049587
29Amphetamine addiction_Homo sapiens_hsa050311.72142119
30Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.72011958
31Fanconi anemia pathway_Homo sapiens_hsa034601.68407441
32Parkinsons disease_Homo sapiens_hsa050121.67936988
33Olfactory transduction_Homo sapiens_hsa047401.58706717
34Selenocompound metabolism_Homo sapiens_hsa004501.51777291
35Glycerolipid metabolism_Homo sapiens_hsa005611.46373872
36Ether lipid metabolism_Homo sapiens_hsa005651.41209477
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.40767630
38Sulfur metabolism_Homo sapiens_hsa009201.40330774
39Glycerophospholipid metabolism_Homo sapiens_hsa005641.37564678
40PPAR signaling pathway_Homo sapiens_hsa033201.35827215
41Intestinal immune network for IgA production_Homo sapiens_hsa046721.35169058
42N-Glycan biosynthesis_Homo sapiens_hsa005101.33547695
43Chemical carcinogenesis_Homo sapiens_hsa052041.32575918
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.30703425
45Type I diabetes mellitus_Homo sapiens_hsa049401.28552953
46Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.27396946
47Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.26494122
48Oocyte meiosis_Homo sapiens_hsa041141.25635432
49Primary bile acid biosynthesis_Homo sapiens_hsa001201.24464983
50Purine metabolism_Homo sapiens_hsa002301.23923757
51Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.23225297
52Peroxisome_Homo sapiens_hsa041461.22371165
53Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.22266185
54Fatty acid degradation_Homo sapiens_hsa000711.22005698
55Pentose phosphate pathway_Homo sapiens_hsa000301.20808121
56Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.19843105
57Antigen processing and presentation_Homo sapiens_hsa046121.18976115
58Steroid hormone biosynthesis_Homo sapiens_hsa001401.18849939
59Morphine addiction_Homo sapiens_hsa050321.18132555
60RNA polymerase_Homo sapiens_hsa030201.18115853
61Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.17727707
62Renin secretion_Homo sapiens_hsa049241.17191998
63Retinol metabolism_Homo sapiens_hsa008301.13317732
64Arachidonic acid metabolism_Homo sapiens_hsa005901.10550384
65Other glycan degradation_Homo sapiens_hsa005111.10118702
66Alzheimers disease_Homo sapiens_hsa050101.07797781
67Regulation of autophagy_Homo sapiens_hsa041401.07757194
68Taste transduction_Homo sapiens_hsa047421.02874449
69ABC transporters_Homo sapiens_hsa020101.01474272
70Asthma_Homo sapiens_hsa053101.00083944
71Fat digestion and absorption_Homo sapiens_hsa049750.99422673
72Cocaine addiction_Homo sapiens_hsa050300.97230010
73Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.96909056
74Pancreatic secretion_Homo sapiens_hsa049720.95656688
75Fructose and mannose metabolism_Homo sapiens_hsa000510.94006591
76Ovarian steroidogenesis_Homo sapiens_hsa049130.93995746
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.91378592
78Fatty acid metabolism_Homo sapiens_hsa012120.90994282
79Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.90088898
80Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.89939584
81Serotonergic synapse_Homo sapiens_hsa047260.88971913
82GABAergic synapse_Homo sapiens_hsa047270.87097074
83Salivary secretion_Homo sapiens_hsa049700.83110079
84Thyroid hormone synthesis_Homo sapiens_hsa049180.82735281
85Graft-versus-host disease_Homo sapiens_hsa053320.82401931
86Glutamatergic synapse_Homo sapiens_hsa047240.81427527
87Primary immunodeficiency_Homo sapiens_hsa053400.80969058
88Pentose and glucuronate interconversions_Homo sapiens_hsa000400.80727114
89beta-Alanine metabolism_Homo sapiens_hsa004100.79758301
90Allograft rejection_Homo sapiens_hsa053300.79389307
91Estrogen signaling pathway_Homo sapiens_hsa049150.78634835
92Autoimmune thyroid disease_Homo sapiens_hsa053200.77317775
93Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.76670279
94Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.76514105
95Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75617693
96Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73550010
97Sphingolipid metabolism_Homo sapiens_hsa006000.71321151
98Mineral absorption_Homo sapiens_hsa049780.68684236
99Collecting duct acid secretion_Homo sapiens_hsa049660.68626008
100RNA degradation_Homo sapiens_hsa030180.68547212
101Circadian entrainment_Homo sapiens_hsa047130.68398931
102Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.68389778
103cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64599137
104Type II diabetes mellitus_Homo sapiens_hsa049300.63790905
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63306849
106Pyrimidine metabolism_Homo sapiens_hsa002400.61842922
107One carbon pool by folate_Homo sapiens_hsa006700.61392074
108Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60036445
109Long-term potentiation_Homo sapiens_hsa047200.59168153
110Rheumatoid arthritis_Homo sapiens_hsa053230.58229394
111AMPK signaling pathway_Homo sapiens_hsa041520.55264489
112Legionellosis_Homo sapiens_hsa051340.54427931
113Cardiac muscle contraction_Homo sapiens_hsa042600.53247370
114Vascular smooth muscle contraction_Homo sapiens_hsa042700.52993946
115Glutathione metabolism_Homo sapiens_hsa004800.52751177
116SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52225885
117Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51951299
118Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.51731749
119Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51594927
120Insulin resistance_Homo sapiens_hsa049310.48507129
121Homologous recombination_Homo sapiens_hsa034400.46650527
122Renin-angiotensin system_Homo sapiens_hsa046140.46439486
123Protein digestion and absorption_Homo sapiens_hsa049740.44961708
124mRNA surveillance pathway_Homo sapiens_hsa030150.43013435
125cAMP signaling pathway_Homo sapiens_hsa040240.42032568
126Gastric acid secretion_Homo sapiens_hsa049710.41776374
127Metabolic pathways_Homo sapiens_hsa011000.41680087
128Circadian rhythm_Homo sapiens_hsa047100.40351541
129Vibrio cholerae infection_Homo sapiens_hsa051100.39941531
130Carbon metabolism_Homo sapiens_hsa012000.39102026
131Cysteine and methionine metabolism_Homo sapiens_hsa002700.38956952
132RNA transport_Homo sapiens_hsa030130.38955917
133Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.38344286
134Calcium signaling pathway_Homo sapiens_hsa040200.37561913
135Dopaminergic synapse_Homo sapiens_hsa047280.37307604
136Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.36815678
137Nucleotide excision repair_Homo sapiens_hsa034200.36154241
138Inositol phosphate metabolism_Homo sapiens_hsa005620.34282353
139Phosphatidylinositol signaling system_Homo sapiens_hsa040700.32324827
140Tyrosine metabolism_Homo sapiens_hsa003500.32197154
141Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.32143325
142Vitamin digestion and absorption_Homo sapiens_hsa049770.32009703
143Alcoholism_Homo sapiens_hsa050340.30254874
144Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.30139040
145Aldosterone synthesis and secretion_Homo sapiens_hsa049250.29814509
146Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.28119796
147Synaptic vesicle cycle_Homo sapiens_hsa047210.27835579
148Prolactin signaling pathway_Homo sapiens_hsa049170.27669481
149Hedgehog signaling pathway_Homo sapiens_hsa043400.27188834
150Histidine metabolism_Homo sapiens_hsa003400.26781143
151Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.25064231
152Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.22890955
153Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.22263259

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