LRRC43

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell-cell recognition (GO:0009988)9.87602586
2binding of sperm to zona pellucida (GO:0007339)9.75103584
3epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.37695022
4reproduction (GO:0000003)9.28649414
5regulation of cilium movement (GO:0003352)8.84672430
6spermatid development (GO:0007286)8.75323784
7single fertilization (GO:0007338)7.51375876
8piRNA metabolic process (GO:0034587)7.31750196
9sperm capacitation (GO:0048240)7.26750461
10male meiosis (GO:0007140)7.23601848
11synaptonemal complex organization (GO:0070193)6.66416419
12ventricular system development (GO:0021591)6.54896829
13synaptonemal complex assembly (GO:0007130)6.34230205
14negative regulation of inclusion body assembly (GO:0090084)6.21568150
15fertilization (GO:0009566)6.12708710
16spermatogenesis (GO:0007283)5.90272183
17male gamete generation (GO:0048232)5.87908345
18vitamin transmembrane transport (GO:0035461)5.66230684
19microtubule depolymerization (GO:0007019)5.54520303
20organic cation transport (GO:0015695)5.54105547
21primary alcohol catabolic process (GO:0034310)5.50596950
22gamete generation (GO:0007276)5.41543383
23regulation of microtubule-based movement (GO:0060632)5.35538979
24regulation of inclusion body assembly (GO:0090083)5.25900991
25calcium ion-dependent exocytosis (GO:0017156)5.22461119
26microtubule severing (GO:0051013)5.06717630
27spermatid nucleus differentiation (GO:0007289)5.04475798
28cell recognition (GO:0008037)5.01537149
29male meiosis I (GO:0007141)4.99192022
30cellular process involved in reproduction in multicellular organism (GO:0022412)4.95432436
31response to xenobiotic stimulus (GO:0009410)4.92929213
32germ cell development (GO:0007281)4.86952258
33axoneme assembly (GO:0035082)4.71367397
34pyrimidine-containing compound transmembrane transport (GO:0072531)4.68746969
35ethanol metabolic process (GO:0006067)4.68644824
36DNA methylation involved in gamete generation (GO:0043046)4.56525834
37negative regulation of T cell differentiation in thymus (GO:0033085)4.38030431
38left/right pattern formation (GO:0060972)4.33632010
39chromosome organization involved in meiosis (GO:0070192)4.32441045
40cell projection assembly (GO:0030031)4.31933312
41protein localization to cilium (GO:0061512)4.30767330
42diterpenoid biosynthetic process (GO:0016102)4.30304173
43multicellular organismal reproductive process (GO:0048609)4.27315313
44protein polyglutamylation (GO:0018095)4.26785536
45nucleoside diphosphate phosphorylation (GO:0006165)4.19592473
46intraciliary transport (GO:0042073)4.17167688
47meiotic nuclear division (GO:0007126)4.13619273
48lung epithelium development (GO:0060428)4.13523937
49one-carbon compound transport (GO:0019755)4.01026718
50meiosis I (GO:0007127)3.97717263
51glycerol ether metabolic process (GO:0006662)3.95021668
52establishment of apical/basal cell polarity (GO:0035089)3.88831261
53seminiferous tubule development (GO:0072520)3.87281992
54cilium organization (GO:0044782)3.86883856
55establishment or maintenance of monopolar cell polarity (GO:0061339)3.84428368
56establishment of monopolar cell polarity (GO:0061162)3.84428368
57centriole assembly (GO:0098534)3.84411103
58GTP biosynthetic process (GO:0006183)3.78671565
59chaperone-mediated protein complex assembly (GO:0051131)3.74989689
60establishment of planar polarity (GO:0001736)3.73606907
61establishment of tissue polarity (GO:0007164)3.73606907
62cilium assembly (GO:0042384)3.72383122
63exogenous drug catabolic process (GO:0042738)3.71301314
64tolerance induction (GO:0002507)3.69893993
65microtubule-based movement (GO:0007018)3.67446980
66ether metabolic process (GO:0018904)3.66083008
67determination of left/right symmetry (GO:0007368)3.64711277
68cytoplasmic microtubule organization (GO:0031122)3.57660733
69cilium morphogenesis (GO:0060271)3.57421298
70nonmotile primary cilium assembly (GO:0035058)3.56837389
71lateral ventricle development (GO:0021670)3.54274548
72negative regulation of immunoglobulin mediated immune response (GO:0002890)3.53858909
73negative regulation of B cell mediated immunity (GO:0002713)3.53858909
74meiotic cell cycle (GO:0051321)3.50573019
75determination of bilateral symmetry (GO:0009855)3.48175094
76cellular component assembly involved in morphogenesis (GO:0010927)3.47036423
77regulation of interleukin-5 production (GO:0032674)3.44149973
78chromosome condensation (GO:0030261)3.43507458
79specification of symmetry (GO:0009799)3.39473635
80multicellular organismal development (GO:0007275)3.38530560
81ethanol oxidation (GO:0006069)3.37189321
82UTP biosynthetic process (GO:0006228)3.35242325
83smoothened signaling pathway (GO:0007224)3.33661459
84terpenoid biosynthetic process (GO:0016114)3.32831753
85retinoic acid metabolic process (GO:0042573)3.31917772
86DNA packaging (GO:0006323)3.30074321
87centriole replication (GO:0007099)3.27972185
88glomerular epithelial cell development (GO:0072310)3.26449536
89cornea development in camera-type eye (GO:0061303)3.26139956
90genitalia morphogenesis (GO:0035112)3.10245752
91negative regulation of humoral immune response (GO:0002921)3.02886098
92UTP metabolic process (GO:0046051)3.01233540
93lateral sprouting from an epithelium (GO:0060601)3.01055460
94glutathione derivative biosynthetic process (GO:1901687)2.97251386
95glutathione derivative metabolic process (GO:1901685)2.97251386
96regulation of interleukin-13 production (GO:0032656)2.96334153
97drug catabolic process (GO:0042737)2.96220473
98regulation of germinal center formation (GO:0002634)2.95677998
99amino-acid betaine transport (GO:0015838)2.95617291
100carnitine transport (GO:0015879)2.95617291
101protein refolding (GO:0042026)2.92572092
102left/right axis specification (GO:0070986)2.91131938
103regulation of centriole replication (GO:0046599)2.90216046
104monoubiquitinated protein deubiquitination (GO:0035520)2.90122450
105sexual reproduction (GO:0019953)2.89099699
106microtubule polymerization or depolymerization (GO:0031109)2.87359986
107carnitine transmembrane transport (GO:1902603)2.85843537
108single strand break repair (GO:0000012)2.83949425
109carnitine metabolic process (GO:0009437)2.81824559
110positive regulation of tolerance induction (GO:0002645)2.75229722
111negative regulation of organelle assembly (GO:1902116)2.75140230
112organelle assembly (GO:0070925)2.74303444
113neurotransmitter metabolic process (GO:0042133)2.73803301
114aldehyde catabolic process (GO:0046185)2.73184602
115microtubule-based process (GO:0007017)2.71561659
116protein K11-linked deubiquitination (GO:0035871)2.71500472
117positive regulation of smoothened signaling pathway (GO:0045880)2.69537689
118alditol metabolic process (GO:0019400)2.68416932
119regulation of spindle checkpoint (GO:0090231)2.67038413
120peptidyl-glutamic acid modification (GO:0018200)2.66290461
121regulation of collateral sprouting (GO:0048670)2.65599059
122glycolytic process (GO:0006096)2.63453166
123primary alcohol metabolic process (GO:0034308)2.61045447
124rRNA catabolic process (GO:0016075)2.59849049
125retinal cone cell development (GO:0046549)2.59360228
126nucleus organization (GO:0006997)2.59230345
127retinol metabolic process (GO:0042572)2.58411012
128polyol catabolic process (GO:0046174)2.57206271
129synapsis (GO:0007129)2.54965468
130photoreceptor cell maintenance (GO:0045494)2.54635373
131meiotic cell cycle process (GO:1903046)2.54112607
132regulation of autophagic vacuole assembly (GO:2000785)2.53501574
133guanosine-containing compound biosynthetic process (GO:1901070)2.53076755
134retinal rod cell development (GO:0046548)2.51592194
135lactate metabolic process (GO:0006089)2.48485218
136hydrogen peroxide biosynthetic process (GO:0050665)2.47590194
137gene silencing by RNA (GO:0031047)2.45465418
138microtubule bundle formation (GO:0001578)2.45106986
139spinal cord motor neuron differentiation (GO:0021522)2.45022403
140CTP biosynthetic process (GO:0006241)2.43879527
141CTP metabolic process (GO:0046036)2.43879527
142neurotransmitter biosynthetic process (GO:0042136)2.43138498
143regulation of interleukin-6 biosynthetic process (GO:0045408)2.42851894
144heart looping (GO:0001947)2.42501132
145positive regulation of macrophage activation (GO:0043032)2.42090599
146O-glycan processing (GO:0016266)2.39376018
147phenol-containing compound catabolic process (GO:0019336)2.37045309
148regulation of smoothened signaling pathway (GO:0008589)2.34638488
149neurotransmitter catabolic process (GO:0042135)2.33771337
150excretion (GO:0007588)2.32869772
151negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.28578543
152calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)2.26096209
153regulation of vacuole organization (GO:0044088)2.23998419
154intra-S DNA damage checkpoint (GO:0031573)2.23797275
155cilium or flagellum-dependent cell motility (GO:0001539)13.8699079
156fusion of sperm to egg plasma membrane (GO:0007342)13.2826514
157sperm motility (GO:0030317)12.3153840
158axonemal dynein complex assembly (GO:0070286)11.9646246
159cell wall macromolecule metabolic process (GO:0044036)11.8958651
160cell wall macromolecule catabolic process (GO:0016998)11.8958651
161acrosome assembly (GO:0001675)11.1737514
162epithelial cilium movement (GO:0003351)11.1308341
163multicellular organism reproduction (GO:0032504)11.1137790
164sperm-egg recognition (GO:0035036)11.0466277
165acrosome reaction (GO:0007340)10.8616047
166motile cilium assembly (GO:0044458)10.5052305
167cilium movement (GO:0003341)10.3541845
168plasma membrane fusion (GO:0045026)10.1219700

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.22225527
2EZH2_22144423_ChIP-Seq_EOC_Human4.55954114
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.48856695
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.94360688
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.90596710
6DROSHA_22980978_ChIP-Seq_HELA_Human2.92234673
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.59238511
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.51090033
9FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.32323450
10GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.32107233
11CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.30668401
12VDR_22108803_ChIP-Seq_LS180_Human2.11804089
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.06534809
14ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.01554228
15ZNF274_21170338_ChIP-Seq_K562_Hela1.97485914
16EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.90768667
17PCGF2_27294783_Chip-Seq_ESCs_Mouse1.90533701
18GATA1_26923725_Chip-Seq_HPCs_Mouse1.88157553
19PIAS1_25552417_ChIP-Seq_VCAP_Human1.87644478
20CBX2_27304074_Chip-Seq_ESCs_Mouse1.87481243
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.85258373
22KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.76751923
23TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.75150202
24IGF1R_20145208_ChIP-Seq_DFB_Human1.74415345
25KAP1_22055183_ChIP-Seq_ESCs_Mouse1.69251107
26CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.68222372
27NR3C1_21868756_ChIP-Seq_MCF10A_Human1.67794328
28MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.67293872
29ELK4_26923725_Chip-Seq_MESODERM_Mouse1.67152346
30STAT1_17558387_ChIP-Seq_HELA_Human1.59668881
31PCGF2_27294783_Chip-Seq_NPCs_Mouse1.58643968
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.57176558
33KDM2B_26808549_Chip-Seq_REH_Human1.55176215
34REST_21632747_ChIP-Seq_MESCs_Mouse1.51746673
35WDR5_24793694_ChIP-Seq_LNCAP_Human1.51685017
36RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.51540436
37GBX2_23144817_ChIP-Seq_PC3_Human1.49612715
38TAL1_26923725_Chip-Seq_HPCs_Mouse1.49029084
39NFE2_27457419_Chip-Seq_LIVER_Mouse1.48999674
40AHR_22903824_ChIP-Seq_MCF-7_Human1.48862940
41GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.47519657
42SMAD4_21799915_ChIP-Seq_A2780_Human1.47500693
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46965379
44SUZ12_27294783_Chip-Seq_NPCs_Mouse1.46665820
45CTBP2_25329375_ChIP-Seq_LNCAP_Human1.46509647
46SOX2_22085726_ChIP-Seq_NPCs_Mouse1.46234623
47TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.44865513
48BCAT_22108803_ChIP-Seq_LS180_Human1.43705826
49CBP_20019798_ChIP-Seq_JUKART_Human1.42752219
50IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.42752219
51TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.41320493
52ZFP57_27257070_Chip-Seq_ESCs_Mouse1.40659359
53ETV1_20927104_ChIP-Seq_GIST48_Human1.40299738
54ESR1_20079471_ChIP-ChIP_T-47D_Human1.39076757
55SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.37649960
56STAT6_21828071_ChIP-Seq_BEAS2B_Human1.37444495
57ARNT_22903824_ChIP-Seq_MCF-7_Human1.37374908
58* GATA3_21867929_ChIP-Seq_CD8_Mouse1.36347309
59CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.34843441
60TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34253124
61POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.34253124
62FLI1_21867929_ChIP-Seq_TH2_Mouse1.34176156
63EZH2_27294783_Chip-Seq_ESCs_Mouse1.33807217
64RNF2_27304074_Chip-Seq_NSC_Mouse1.32016449
65TCF4_22108803_ChIP-Seq_LS180_Human1.31290982
66TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.31271381
67FOXM1_26456572_ChIP-Seq_MCF-7_Human1.30994353
68STAT3_23295773_ChIP-Seq_U87_Human1.30694272
69LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.29806611
70FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.28853968
71NANOG_18555785_Chip-Seq_ESCs_Mouse1.28814756
72CRX_20693478_ChIP-Seq_RETINA_Mouse1.27798546
73FOXA1_27270436_Chip-Seq_PROSTATE_Human1.26371311
74FOXA1_25329375_ChIP-Seq_VCAP_Human1.26371311
75PHF8_20622853_ChIP-Seq_HELA_Human1.26109896
76PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.25998638
77TAF15_26573619_Chip-Seq_HEK293_Human1.24471761
78PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.22362933
79TDRD3_21172665_ChIP-Seq_MCF-7_Human1.22197234
80AR_20517297_ChIP-Seq_VCAP_Human1.20839387
81TCF4_23295773_ChIP-Seq_U87_Human1.20809222
82OCT4_18555785_Chip-Seq_ESCs_Mouse1.20638529
83EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.20430222
84STAT1_20625510_ChIP-Seq_HELA_Human1.18766313
85GF1_26923725_Chip-Seq_HPCs_Mouse1.18720399
86RBPJ_21746931_ChIP-Seq_IB4_Human1.18536185
87POU3F2_20337985_ChIP-ChIP_501MEL_Human1.18200387
88P53_22387025_ChIP-Seq_ESCs_Mouse1.18110715
89ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.18037429
90ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.18000256
91TP63_23658742_ChIP-Seq_EP156T_Human1.16928773
92PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.16908113
93MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16191245
94MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15920404
95CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.15440746
96P53_21459846_ChIP-Seq_SAOS-2_Human1.15403351
97RUNX2_22187159_ChIP-Seq_PCA_Human1.15099395
98* GATA3_21867929_ChIP-Seq_TH1_Mouse1.15039152
99CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15015388
100SMRT_27268052_Chip-Seq_Bcells_Human1.14941560
101SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.14811506
102CMYC_18555785_Chip-Seq_ESCs_Mouse1.13963587
103BMI1_23680149_ChIP-Seq_NPCS_Mouse1.13695840
104NFYA_21822215_ChIP-Seq_K562_Human1.13650915
105AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.13611538
106HNFA_21074721_ChIP-Seq_CACO-2_Human1.13510050
107EZH2_27294783_Chip-Seq_NPCs_Mouse1.13292040
108FUS_26573619_Chip-Seq_HEK293_Human1.13055376
109P300_18555785_Chip-Seq_ESCs_Mouse1.12511164
110FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.11989155
111CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.11707770
112SMAD3_21741376_ChIP-Seq_EPCs_Human1.11274488
113CBX2_22325352_ChIP-Seq_293T-Rex_Human1.10804989
114ESRRB_18555785_Chip-Seq_ESCs_Mouse1.10586669
115SMAD4_21741376_ChIP-Seq_EPCs_Human1.10545205
116KLF4_18555785_Chip-Seq_ESCs_Mouse1.10393154
117OCT4_21477851_ChIP-Seq_ESCs_Mouse1.09334826
118NCOR_22424771_ChIP-Seq_293T_Human1.09200137
119P300_19829295_ChIP-Seq_ESCs_Human1.08061952
120EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.07719953
121EWS_26573619_Chip-Seq_HEK293_Human1.06543056
122SUZ12_18555785_Chip-Seq_ESCs_Mouse1.06381896
123CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05133031
124STAT3_18555785_Chip-Seq_ESCs_Mouse1.04680861
125TRIM28_21343339_ChIP-Seq_HEK293_Human1.04191759
126RAD21_21589869_ChIP-Seq_MESCs_Mouse1.03485801
127GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.02297610
128AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.01565658
129MYC_19829295_ChIP-Seq_ESCs_Human1.01340936
130AR_25329375_ChIP-Seq_VCAP_Human1.01248856
131GATA3_21878914_ChIP-Seq_MCF-7_Human1.01031834
132ERG_20517297_ChIP-Seq_VCAP_Human1.00833964
133RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00662912
134SOX2_18555785_Chip-Seq_ESCs_Mouse1.00342227
135GATA6_21074721_ChIP-Seq_CACO-2_Human0.99045125
136RUNX1_26923725_Chip-Seq_HPCs_Mouse0.98887545
137FOXA1_25552417_ChIP-Seq_VCAP_Human0.98737983
138CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.98495680
139FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98406268
140SMC4_20622854_ChIP-Seq_HELA_Human0.97656899
141PU1_27457419_Chip-Seq_LIVER_Mouse0.97474686
142SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97409735
143NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.97182820
144SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.96730576
145E2F1_18555785_Chip-Seq_ESCs_Mouse0.96652296
146NFYB_21822215_ChIP-Seq_K562_Human0.96084138
147PRDM14_20953172_ChIP-Seq_ESCs_Human0.95831596
148TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.95751569
149SPI1_26923725_Chip-Seq_HPCs_Mouse0.95701315
150PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.95197673
151* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94934908
152CTCF_18555785_Chip-Seq_ESCs_Mouse0.94530055
153TP63_22573176_ChIP-Seq_HFKS_Human0.94235792
154GF1B_26923725_Chip-Seq_HPCs_Mouse0.93570284
155RUNX1_27457419_Chip-Seq_LIVER_Mouse0.93568228
156CTCF_27219007_Chip-Seq_Bcells_Human0.93440472
157SUZ12_27294783_Chip-Seq_ESCs_Mouse0.93081011
158OCT4_20526341_ChIP-Seq_ESCs_Human0.93038514
159HOXB7_26014856_ChIP-Seq_BT474_Human0.92747699
160EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.92599084
161TBL1_22424771_ChIP-Seq_293T_Human0.92240928
162ER_23166858_ChIP-Seq_MCF-7_Human0.92077063
163YY1_22570637_ChIP-Seq_MALME-3M_Human0.91786542
164SOX9_26525672_Chip-Seq_HEART_Mouse0.91078280
165ESET_19884257_ChIP-Seq_ESCs_Mouse0.90728485
166ZFX_18555785_Chip-Seq_ESCs_Mouse0.89793701
167FLI1_21867929_ChIP-Seq_CD8_Mouse0.87886429
168SMAD1_18555785_Chip-Seq_ESCs_Mouse0.87035354

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008875_abnormal_xenobiotic_pharmacok5.97767305
2MP0003698_abnormal_male_reproductive5.77037275
3MP0001929_abnormal_gametogenesis5.13824998
4MP0002653_abnormal_ependyma_morphology4.28434922
5MP0008877_abnormal_DNA_methylation4.26245182
6MP0002132_abnormal_respiratory_system3.93262227
7MP0002210_abnormal_sex_determination3.33016922
8MP0002161_abnormal_fertility/fecundity3.11738453
9MP0002277_abnormal_respiratory_mucosa3.11013362
10MP0009780_abnormal_chondrocyte_physiolo2.87872447
11MP0001145_abnormal_male_reproductive2.73412758
12MP0005623_abnormal_meninges_morphology2.68123750
13MP0000653_abnormal_sex_gland2.42521279
14MP0008789_abnormal_olfactory_epithelium2.27235657
15MP0005670_abnormal_white_adipose2.19380676
16MP0009046_muscle_twitch2.13187741
17MP0005410_abnormal_fertilization14.8153378
18MP0001984_abnormal_olfaction1.96666902
19MP0000383_abnormal_hair_follicle1.87450699
20MP0005423_abnormal_somatic_nervous1.86642953
21MP0002638_abnormal_pupillary_reflex1.85954444
22MP0001485_abnormal_pinna_reflex1.78857904
23MP0002282_abnormal_trachea_morphology1.78848005
24MP0002160_abnormal_reproductive_system1.72810039
25MP0002876_abnormal_thyroid_physiology1.70271067
26MP0004019_abnormal_vitamin_homeostasis1.61696850
27MP0005083_abnormal_biliary_tract1.55147953
28MP0000566_synostosis1.49868698
29MP0003646_muscle_fatigue1.49436571
30MP0005394_taste/olfaction_phenotype1.46860594
31MP0005499_abnormal_olfactory_system1.46860594
32MP0002102_abnormal_ear_morphology1.42459620
33MP0003195_calcinosis1.39532487
34MP0008995_early_reproductive_senescence1.37800271
35MP0002168_other_aberrant_phenotype1.36977029
36MP0003136_yellow_coat_color1.35945071
37MP0002735_abnormal_chemical_nociception1.35908856
38MP0004233_abnormal_muscle_weight1.33401159
39MP0002234_abnormal_pharynx_morphology1.32410024
40MP0010678_abnormal_skin_adnexa1.21419033
41MP0003806_abnormal_nucleotide_metabolis1.16983742
42MP0005248_abnormal_Harderian_gland1.15840589
43MP0003878_abnormal_ear_physiology1.13581612
44MP0005377_hearing/vestibular/ear_phenot1.13581612
45MP0008872_abnormal_physiological_respon1.13256156
46MP0001765_abnormal_ion_homeostasis1.13246829
47MP0006276_abnormal_autonomic_nervous1.11654400
48MP0001970_abnormal_pain_threshold1.08731676
49MP0000049_abnormal_middle_ear1.00760050
50MP0005647_abnormal_sex_gland1.00466025
51MP0006072_abnormal_retinal_apoptosis1.00255182
52MP0004142_abnormal_muscle_tone0.97860073
53MP0005195_abnormal_posterior_eye0.95173241
54MP0002233_abnormal_nose_morphology0.91164268
55MP0002249_abnormal_larynx_morphology0.89993399
56MP0000778_abnormal_nervous_system0.88634078
57MP0009379_abnormal_foot_pigmentation0.87050766
58MP0005395_other_phenotype0.83840968
59MP0005365_abnormal_bile_salt0.82856431
60MP0000955_abnormal_spinal_cord0.82186257
61MP0005389_reproductive_system_phenotype0.81737404
62MP0003950_abnormal_plasma_membrane0.80435968
63MP0002822_catalepsy0.79810755
64MP0000678_abnormal_parathyroid_gland0.79788707
65MP0010030_abnormal_orbit_morphology0.79386109
66MP0005645_abnormal_hypothalamus_physiol0.78496031
67MP0001346_abnormal_lacrimal_gland0.77497931
68MP0001986_abnormal_taste_sensitivity0.76820791
69MP0005220_abnormal_exocrine_pancreas0.76107646
70MP0005551_abnormal_eye_electrophysiolog0.68960298
71MP0003937_abnormal_limbs/digits/tail_de0.68724385
72MP0008058_abnormal_DNA_repair0.66259891
73MP0003115_abnormal_respiratory_system0.65899909
74MP0009643_abnormal_urine_homeostasis0.65878908
75MP0002928_abnormal_bile_duct0.65751252
76MP0004742_abnormal_vestibular_system0.65213674
77MP0003938_abnormal_ear_development0.65064989
78MP0004133_heterotaxia0.64514880
79MP0002067_abnormal_sensory_capabilities0.64500318
80MP0003633_abnormal_nervous_system0.63856619
81MP0004270_analgesia0.63794378
82MP0001968_abnormal_touch/_nociception0.63599427
83MP0004036_abnormal_muscle_relaxation0.63532814
84MP0001944_abnormal_pancreas_morphology0.62565672
85MP0002116_abnormal_craniofacial_bone0.61886884
86MP0004147_increased_porphyrin_level0.59577694
87MP0002136_abnormal_kidney_physiology0.59398095
88MP0002736_abnormal_nociception_after0.59197356
89MP0000647_abnormal_sebaceous_gland0.58835195
90MP0000427_abnormal_hair_cycle0.58579857
91MP0002572_abnormal_emotion/affect_behav0.58501190
92MP0003283_abnormal_digestive_organ0.57945993
93MP0005253_abnormal_eye_physiology0.57693941
94MP0005646_abnormal_pituitary_gland0.55819487
95MP0005636_abnormal_mineral_homeostasis0.51278044
96MP0001440_abnormal_grooming_behavior0.50835550
97MP0003879_abnormal_hair_cell0.48880599
98MP0002152_abnormal_brain_morphology0.48134082
99MP0001963_abnormal_hearing_physiology0.47691162
100MP0003329_amyloid_beta_deposits0.47395344
101MP0004885_abnormal_endolymph0.45328454
102MP0003635_abnormal_synaptic_transmissio0.45245041
103MP0003699_abnormal_female_reproductive0.45152317
104MP0003942_abnormal_urinary_system0.44795863
105MP0003631_nervous_system_phenotype0.41941196
106MP0000026_abnormal_inner_ear0.41411370
107MP0002064_seizures0.40484543
108MP0000631_abnormal_neuroendocrine_gland0.40365070
109MP0001502_abnormal_circadian_rhythm0.40329047
110MP0001486_abnormal_startle_reflex0.40125031
111MP0003011_delayed_dark_adaptation0.39635418
112MP0002557_abnormal_social/conspecific_i0.38750473
113MP0003861_abnormal_nervous_system0.38356762
114MP0009115_abnormal_fat_cell0.37541678
115MP0002272_abnormal_nervous_system0.37288867
116MP0002063_abnormal_learning/memory/cond0.35870109
117MP0002752_abnormal_somatic_nervous0.35577370
118MP0001324_abnormal_eye_pigmentation0.35576089
119MP0003634_abnormal_glial_cell0.35248682
120MP0004811_abnormal_neuron_physiology0.35152905
121MP0005391_vision/eye_phenotype0.34615266
122MP0009745_abnormal_behavioral_response0.34350872
123MP0002971_abnormal_brown_adipose0.33958917
124MP0002734_abnormal_mechanical_nocicepti0.33848261
125MP0003786_premature_aging0.33794448
126MP0002133_abnormal_respiratory_system0.33595438
127MP0005388_respiratory_system_phenotype0.33595438
128MP0001293_anophthalmia0.33553293
129MP0001727_abnormal_embryo_implantation0.33537841
130MP0004134_abnormal_chest_morphology0.32943035
131MP0002882_abnormal_neuron_morphology0.32654611
132MP0002229_neurodegeneration0.30874819
133MP0001270_distended_abdomen0.30800820
134MP0009250_abnormal_appendicular_skeleto0.29643853
135MP0003045_fibrosis0.29584586
136MP0001119_abnormal_female_reproductive0.28859759
137MP0000358_abnormal_cell_content/0.28282860
138MP0003122_maternal_imprinting0.28123003
139MP0002269_muscular_atrophy0.27615232
140MP0008569_lethality_at_weaning0.27053399
141MP0000462_abnormal_digestive_system0.27041797
142MP0004043_abnormal_pH_regulation0.27034429
143MP0003183_abnormal_peptide_metabolism0.26931057
144MP0004145_abnormal_muscle_electrophysio0.26930622
145MP0000534_abnormal_ureter_morphology0.26699523
146MP0001545_abnormal_hematopoietic_system0.25584878
147MP0005397_hematopoietic_system_phenotyp0.25584878
148MP0003787_abnormal_imprinting0.25349337
149MP0002909_abnormal_adrenal_gland0.24821508
150MP0004859_abnormal_synaptic_plasticity0.24731008
151MP0005409_darkened_coat_color0.24349188

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.76846655
2Abnormal respiratory motile cilium morphology (HP:0005938)9.76846655
3Abnormal ciliary motility (HP:0012262)9.35058280
4Rhinitis (HP:0012384)8.59327184
5Chronic bronchitis (HP:0004469)6.82048237
6Nasal polyposis (HP:0100582)6.22671850
7Infertility (HP:0000789)5.98097278
8Abnormality of the nasal mucosa (HP:0000433)5.11716311
9Bronchiectasis (HP:0002110)5.09007120
10Bronchitis (HP:0012387)4.35249402
11Nephronophthisis (HP:0000090)4.15124307
12Male infertility (HP:0003251)3.83991339
13Recurrent sinusitis (HP:0011108)3.49170142
14Recurrent otitis media (HP:0000403)3.25981950
15Chronic hepatic failure (HP:0100626)3.20050556
16Abnormality of the renal medulla (HP:0100957)3.17114898
17Medial flaring of the eyebrow (HP:0010747)3.09078561
18Tubulointerstitial nephritis (HP:0001970)2.77295243
19Recurrent bronchitis (HP:0002837)2.70716845
20Abnormal spermatogenesis (HP:0008669)2.70094240
21Chronic sinusitis (HP:0011109)2.60320808
22Atelectasis (HP:0100750)2.56594374
23Chronic otitis media (HP:0000389)2.54782560
24Molar tooth sign on MRI (HP:0002419)2.53375406
25Abnormality of midbrain morphology (HP:0002418)2.53375406
26Hyperactive renin-angiotensin system (HP:0000841)2.39637569
27Male pseudohermaphroditism (HP:0000037)2.28988654
28Gait imbalance (HP:0002141)2.26239687
29Congenital primary aphakia (HP:0007707)2.23749387
30Tubular atrophy (HP:0000092)2.19109034
31Tubulointerstitial abnormality (HP:0001969)2.17334691
32Pancreatic fibrosis (HP:0100732)2.15748450
33Postaxial foot polydactyly (HP:0001830)2.12347706
34Furrowed tongue (HP:0000221)2.11416657
35Aplasia/Hypoplasia of the spleen (HP:0010451)2.08053479
36Congenital hepatic fibrosis (HP:0002612)2.07220322
37True hermaphroditism (HP:0010459)2.03347688
38Asplenia (HP:0001746)2.02743230
39Impulsivity (HP:0100710)2.01031265
40Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.2351568
41Absent/shortened dynein arms (HP:0200106)12.4721954
42Dynein arm defect of respiratory motile cilia (HP:0012255)12.4721954
43Abnormal respiratory motile cilium physiology (HP:0012261)10.4428848
44Decreased circulating renin level (HP:0003351)1.96567803
45Nephrogenic diabetes insipidus (HP:0009806)1.95571200
46Renal dysplasia (HP:0000110)1.91506423
47Stage 5 chronic kidney disease (HP:0003774)1.84904247
48Azoospermia (HP:0000027)1.84573826
49Median cleft lip (HP:0000161)1.83945618
50Fibular hypoplasia (HP:0003038)1.83603804
51Aplasia/Hypoplasia of the lens (HP:0008063)1.83114054
52Abnormality of dentin (HP:0010299)1.81065149
53Supernumerary spleens (HP:0009799)1.80559219
54Bile duct proliferation (HP:0001408)1.80039880
55Abnormal biliary tract physiology (HP:0012439)1.80039880
56Gonadotropin excess (HP:0000837)1.79787818
57Abnormality of the dental root (HP:0006486)1.77050472
58Taurodontia (HP:0000679)1.77050472
59Abnormality of permanent molar morphology (HP:0011071)1.77050472
60Preaxial hand polydactyly (HP:0001177)1.76870365
61Genital tract atresia (HP:0001827)1.74140063
62Postaxial hand polydactyly (HP:0001162)1.73566298
63Abnormality of the dental pulp (HP:0006479)1.71697853
64Vaginal atresia (HP:0000148)1.66585629
65Aplasia/Hypoplasia of the tongue (HP:0010295)1.65777179
66Facial cleft (HP:0002006)1.65015114
67Abnormality of molar morphology (HP:0011070)1.64807435
68Abnormality of molar (HP:0011077)1.64807435
69Tubulointerstitial fibrosis (HP:0005576)1.64772368
70Poor coordination (HP:0002370)1.64428606
71Absent rod-and cone-mediated responses on ERG (HP:0007688)1.63864803
72Decreased central vision (HP:0007663)1.62785994
73Polydipsia (HP:0001959)1.62634650
74Abnormal drinking behavior (HP:0030082)1.62634650
75Cystic liver disease (HP:0006706)1.61185469
76Microglossia (HP:0000171)1.58821768
77Abnormality of renal excretion (HP:0011036)1.55889086
78Renal salt wasting (HP:0000127)1.55439075
79Short ribs (HP:0000773)1.54536697
80Bell-shaped thorax (HP:0001591)1.54058057
81Oculomotor apraxia (HP:0000657)1.53372141
82J-shaped sella turcica (HP:0002680)1.48107809
83Hemiparesis (HP:0001269)1.47854894
84Spastic tetraparesis (HP:0001285)1.47556229
85Abnormal gallbladder physiology (HP:0012438)1.47456797
86Cholecystitis (HP:0001082)1.47456797
87Abnormality of the lower motor neuron (HP:0002366)1.45950297
88Abnormality of renin-angiotensin system (HP:0000847)1.43345374
89Abnormal rod and cone electroretinograms (HP:0008323)1.42839083
90Occipital encephalocele (HP:0002085)1.40302736
91Hyperaldosteronism (HP:0000859)1.38562679
92Hypoplasia of the capital femoral epiphysis (HP:0003090)1.38284005
93Narrow forehead (HP:0000341)1.37349280
94Hyperkalemia (HP:0002153)1.36224358
95Abnormal urine output (HP:0012590)1.35477858
96Nephropathy (HP:0000112)1.34663082
97Abnormality of the renal cortex (HP:0011035)1.33919122
98Retinal dysplasia (HP:0007973)1.32624423
99Pancreatic cysts (HP:0001737)1.31588693
100Dyschromatopsia (HP:0007641)1.30358994
101Aganglionic megacolon (HP:0002251)1.28137640
102Retinitis pigmentosa (HP:0000510)1.28122406
103Heterotopia (HP:0002282)1.26464425
104Absent speech (HP:0001344)1.25477139
105Short thorax (HP:0010306)1.25409418
106Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.24101620
107Abnormality of saccadic eye movements (HP:0000570)1.23025041
108Hip dysplasia (HP:0001385)1.22221464
109Amyotrophic lateral sclerosis (HP:0007354)1.21266462
110Cone-rod dystrophy (HP:0000548)1.20682182
111Deformed sella turcica (HP:0002681)1.20287091
112Absent frontal sinuses (HP:0002688)1.20085490
113Optic nerve coloboma (HP:0000588)1.20062829
114Prominent nasal bridge (HP:0000426)1.19037642
115Absent epiphyses (HP:0010577)1.16276415
116Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.16276415
117Congenital malformation of the right heart (HP:0011723)1.15432987
118Double outlet right ventricle (HP:0001719)1.15432987
119Anencephaly (HP:0002323)1.15357298
120Sclerocornea (HP:0000647)1.15246065
121Abnormality of macular pigmentation (HP:0008002)1.14306642
122Tongue fasciculations (HP:0001308)1.13641003
123Aplasia/Hypoplasia of the fibula (HP:0006492)1.12507857
124Hypokalemic alkalosis (HP:0001949)1.12112313
125Polyuria (HP:0000103)1.12023315
126Multicystic kidney dysplasia (HP:0000003)1.11665367
127Abnormality of ocular smooth pursuit (HP:0000617)1.11382237
128Abolished electroretinogram (ERG) (HP:0000550)1.09654729
129Abnormality of chloride homeostasis (HP:0011422)1.08443742
130Highly arched eyebrow (HP:0002553)1.07289575
131Bony spicule pigmentary retinopathy (HP:0007737)1.07275260
132Holoprosencephaly (HP:0001360)1.07091332
133Disproportionate short-trunk short stature (HP:0003521)1.06056672
134Abdominal situs inversus (HP:0003363)1.02556596
135Abnormality of abdominal situs (HP:0011620)1.02556596

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.16275797
2PDK48.16275797
3TESK15.39770717
4PDK25.28436117
5PRKD34.86809722
6MST44.50438854
7ICK3.85204136
8EPHA23.37707472
9PNCK2.63558306
10MAPK152.57370791
11TLK12.43717639
12PTK2B2.38792918
13WNK42.30935336
14FRK2.22498524
15STK392.19745631
16ADRBK22.05348771
17NME11.83654047
18BCR1.76837993
19STK381.63696497
20MAP3K21.46183371
21OXSR11.36811922
22STK241.33566500
23NEK21.30400276
24DYRK1B1.24898567
25MAP4K21.18890586
26MAPK131.12866747
27CASK1.11562294
28PDK11.07918904
29ERBB21.07325612
30IRAK11.01381012
31NTRK21.01310763
32BMPR1B1.00955545
33INSRR0.92731163
34PRKCI0.91877527
35NTRK30.91040324
36LMTK20.88414715
37CAMKK20.87542462
38ADRBK10.85186950
39EPHA40.79537479
40WNK10.76867506
41EPHB10.76584221
42CAMK1G0.74351744
43ERBB30.73298471
44DYRK20.70904143
45TYRO30.70059757
46CSK0.69469372
47ACVR1B0.68997977
48WEE10.68913151
49DYRK30.65473445
50NEK90.62951754
51PDPK10.62451375
52PLK40.61882549
53CDK190.59887573
54MAP3K70.58972796
55CHEK20.58387571
56PRKCE0.57835078
57PRKCH0.57732860
58STK30.55955239
59PASK0.55755584
60TIE10.54174956
61PINK10.53371972
62STK38L0.52382355
63NLK0.52330860
64CCNB10.51501776
65MAP2K70.51278544
66TRPM70.50901565
67BRSK20.49995876
68PRKCG0.49380328
69TRIM280.48491578
70PRKAA20.47809373
71TESK20.46671673
72MAP3K40.45785232
73SGK10.45687827
74IRAK20.44680085
75MAP2K40.43845968
76BRAF0.40259609
77LRRK20.39514944
78TTK0.39446566
79SGK2230.39369045
80SGK4940.39369045
81ZAK0.39218774
82PAK20.39181786
83RIPK40.38566484
84MAP3K30.38139377
85EPHA30.37142946
86PAK10.36412269
87NEK60.36406831
88EEF2K0.35981434
89MUSK0.35753733
90STK100.35479166
91FER0.35219089
92CHEK10.35004598
93TXK0.33927753
94SGK20.33813387
95DYRK1A0.33785737
96STK160.33340050
97MAP3K120.32237710
98PRKCD0.31757449
99UHMK10.31560811
100MET0.31242786
101MARK10.30574679
102PAK60.30537500
103TNK20.30219762
104MAP2K60.29943769
105PHKG10.28487944
106PHKG20.28487944
107ABL10.28474180
108LIMK10.27999283
109BRSK10.27813162
110HIPK20.27024316
111CAMKK10.26795801
112CDK120.26494103
113ATM0.25617496
114OBSCN0.24770232
115ARAF0.23603277
116PKN10.21829340
117CDK30.19990050
118PRKAA10.19920263
119WNK30.19481833
120CAMK2A0.18884580
121YES10.17746845
122ATR0.17102333
123GRK10.16985847
124MARK20.16145624
125MTOR0.14348377
126PLK10.14227302
127PRKG10.14106166
128PRKCZ0.13634510
129MAPKAPK50.12759496
130MAPKAPK30.11343424
131PRKACG0.10558657
132CSNK1D0.09338865
133GSK3B0.08718646
134RPS6KB10.08556906
135MAPK100.07248189
136RPS6KA10.06866938
137STK110.06299365
138TNIK0.05573171
139GRK70.05292606
140PAK30.05211131
141AURKA0.04599289
142PRKG20.03707113
143CAMK2G0.03644984
144PRKCQ0.03536080
145CDK150.03522092
146PRKCA0.03461726
147PRKACA0.03450646
148RPS6KA20.02990698
149PRKDC0.02939706
150CDK10.02785501
151MINK10.02513620
152MKNK20.02468004
153PRKCB0.02263204
154RPS6KA30.01724443
155CSNK2A10.01672607
156CDK180.00987074
157CSNK2A20.00664227

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid biosynthesis_Homo sapiens_hsa000614.66449734
2Vitamin B6 metabolism_Homo sapiens_hsa007504.04596167
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.64543239
4Histidine metabolism_Homo sapiens_hsa003403.39320870
5Caffeine metabolism_Homo sapiens_hsa002323.34785248
6Pyruvate metabolism_Homo sapiens_hsa006203.01579671
7Phenylalanine metabolism_Homo sapiens_hsa003602.88206205
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.75865752
9Propanoate metabolism_Homo sapiens_hsa006402.62309296
10beta-Alanine metabolism_Homo sapiens_hsa004102.59337592
11Tyrosine metabolism_Homo sapiens_hsa003502.53827394
12Glucagon signaling pathway_Homo sapiens_hsa049222.47014078
13Basal transcription factors_Homo sapiens_hsa030222.46312655
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.39311211
15Linoleic acid metabolism_Homo sapiens_hsa005912.29811396
16Carbohydrate digestion and absorption_Homo sapiens_hsa049732.08836737
17Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.04126224
18PPAR signaling pathway_Homo sapiens_hsa033201.97116443
19Retinol metabolism_Homo sapiens_hsa008301.94347110
20Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.89817519
21Dorso-ventral axis formation_Homo sapiens_hsa043201.85200732
22Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.83024029
23Huntingtons disease_Homo sapiens_hsa050161.80822211
24Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.76938558
25Pentose phosphate pathway_Homo sapiens_hsa000301.76486155
26Amphetamine addiction_Homo sapiens_hsa050311.76227922
27Nitrogen metabolism_Homo sapiens_hsa009101.76004644
28Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.73892516
29Glycosaminoglycan degradation_Homo sapiens_hsa005311.65876835
30Glycerolipid metabolism_Homo sapiens_hsa005611.62230597
31Peroxisome_Homo sapiens_hsa041461.60224006
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.60063690
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.59751070
34Oocyte meiosis_Homo sapiens_hsa041141.58577776
35Selenocompound metabolism_Homo sapiens_hsa004501.57276703
36Mineral absorption_Homo sapiens_hsa049781.56351769
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.50890694
38Glycerophospholipid metabolism_Homo sapiens_hsa005641.48156133
39Cardiac muscle contraction_Homo sapiens_hsa042601.48130468
40Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.40129688
41Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.38746180
42Fanconi anemia pathway_Homo sapiens_hsa034601.37549019
43Fructose and mannose metabolism_Homo sapiens_hsa000511.37028859
44Renin secretion_Homo sapiens_hsa049241.36526701
45Ether lipid metabolism_Homo sapiens_hsa005651.25567510
46Insulin secretion_Homo sapiens_hsa049111.25218353
47Steroid hormone biosynthesis_Homo sapiens_hsa001401.23992470
48Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.19747335
49Butanoate metabolism_Homo sapiens_hsa006501.18659703
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.13038008
51Oxidative phosphorylation_Homo sapiens_hsa001901.12405784
52Taste transduction_Homo sapiens_hsa047421.12218301
53Fatty acid metabolism_Homo sapiens_hsa012121.12160876
54Fatty acid degradation_Homo sapiens_hsa000711.08541004
55Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.08212501
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.06595927
57Purine metabolism_Homo sapiens_hsa002301.05697592
58Collecting duct acid secretion_Homo sapiens_hsa049661.02749783
59Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.02533761
60Tight junction_Homo sapiens_hsa045301.02439337
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.02331591
62Carbon metabolism_Homo sapiens_hsa012000.99065368
63Primary bile acid biosynthesis_Homo sapiens_hsa001200.96376933
64Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.93482081
65Regulation of autophagy_Homo sapiens_hsa041400.93153590
66Calcium signaling pathway_Homo sapiens_hsa040200.93025675
67Renin-angiotensin system_Homo sapiens_hsa046140.92983707
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.91808698
69Olfactory transduction_Homo sapiens_hsa047400.91013695
70Tryptophan metabolism_Homo sapiens_hsa003800.90239944
71Bile secretion_Homo sapiens_hsa049760.90171775
72Long-term potentiation_Homo sapiens_hsa047200.89763453
73Antigen processing and presentation_Homo sapiens_hsa046120.89305531
74Estrogen signaling pathway_Homo sapiens_hsa049150.89211349
75Salivary secretion_Homo sapiens_hsa049700.88821934
76Gastric acid secretion_Homo sapiens_hsa049710.88772092
77Fat digestion and absorption_Homo sapiens_hsa049750.87438418
78Thyroid hormone synthesis_Homo sapiens_hsa049180.87382649
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.84836019
80Circadian rhythm_Homo sapiens_hsa047100.83741571
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82929143
82Cysteine and methionine metabolism_Homo sapiens_hsa002700.82208597
83cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81662073
84mRNA surveillance pathway_Homo sapiens_hsa030150.78921919
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77127321
86Synaptic vesicle cycle_Homo sapiens_hsa047210.75210462
87Chemical carcinogenesis_Homo sapiens_hsa052040.73454676
88Hedgehog signaling pathway_Homo sapiens_hsa043400.72729887
89Serotonergic synapse_Homo sapiens_hsa047260.68075395
90Arachidonic acid metabolism_Homo sapiens_hsa005900.67257395
91Glutathione metabolism_Homo sapiens_hsa004800.67214333
92Circadian entrainment_Homo sapiens_hsa047130.65170416
93Pancreatic secretion_Homo sapiens_hsa049720.65045275
94Cocaine addiction_Homo sapiens_hsa050300.65043931
95Nicotine addiction_Homo sapiens_hsa050330.63608739
96cAMP signaling pathway_Homo sapiens_hsa040240.61236273
97Maturity onset diabetes of the young_Homo sapiens_hsa049500.59476380
98Parkinsons disease_Homo sapiens_hsa050120.59147149
99Biosynthesis of amino acids_Homo sapiens_hsa012300.58649903
100ABC transporters_Homo sapiens_hsa020100.58568230
101Protein export_Homo sapiens_hsa030600.54793992
102Protein digestion and absorption_Homo sapiens_hsa049740.54373747
103Glutamatergic synapse_Homo sapiens_hsa047240.53027344
104RNA transport_Homo sapiens_hsa030130.52558152
105Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.52512040
106GABAergic synapse_Homo sapiens_hsa047270.51199771
107Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.49849154
108Vascular smooth muscle contraction_Homo sapiens_hsa042700.48086442
109Alzheimers disease_Homo sapiens_hsa050100.47860679
110N-Glycan biosynthesis_Homo sapiens_hsa005100.47193593
111Ovarian steroidogenesis_Homo sapiens_hsa049130.46819664
112Steroid biosynthesis_Homo sapiens_hsa001000.46558136
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.46440125
114Inositol phosphate metabolism_Homo sapiens_hsa005620.44731173
115Starch and sucrose metabolism_Homo sapiens_hsa005000.42150427
116Drug metabolism - other enzymes_Homo sapiens_hsa009830.41972986
117Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.40764798
118Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.38828049
119Hippo signaling pathway_Homo sapiens_hsa043900.38460904
120Metabolic pathways_Homo sapiens_hsa011000.37704564
121Axon guidance_Homo sapiens_hsa043600.37099274
122Vitamin digestion and absorption_Homo sapiens_hsa049770.36470101
123Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.34544260
124Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.33992139
125Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33555175
126Cyanoamino acid metabolism_Homo sapiens_hsa004600.33349159
127Arginine and proline metabolism_Homo sapiens_hsa003300.32293371
128Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30723232
129Choline metabolism in cancer_Homo sapiens_hsa052310.29434312
130Central carbon metabolism in cancer_Homo sapiens_hsa052300.28902411
131Aldosterone synthesis and secretion_Homo sapiens_hsa049250.28616409
132SNARE interactions in vesicular transport_Homo sapiens_hsa041300.27569823
133Endocytosis_Homo sapiens_hsa041440.26224275
134AMPK signaling pathway_Homo sapiens_hsa041520.26174842
135Wnt signaling pathway_Homo sapiens_hsa043100.25561049
136Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.25158488
137Dopaminergic synapse_Homo sapiens_hsa047280.24937612
138Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.23404271
139Pyrimidine metabolism_Homo sapiens_hsa002400.21114991
140Sphingolipid metabolism_Homo sapiens_hsa006000.20922428
141Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.20147622
142Pentose and glucuronate interconversions_Homo sapiens_hsa000400.18996465
143Basal cell carcinoma_Homo sapiens_hsa052170.18619831
144Sulfur metabolism_Homo sapiens_hsa009200.18017115
145Morphine addiction_Homo sapiens_hsa050320.17043715
146Phototransduction_Homo sapiens_hsa047440.15696421
147Oxytocin signaling pathway_Homo sapiens_hsa049210.15481986

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