LRRC71

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.30868882
2motile cilium assembly (GO:0044458)9.09609674
3axoneme assembly (GO:0035082)8.34868225
4ventricular system development (GO:0021591)8.14168955
5sperm motility (GO:0030317)7.25452682
6fusion of sperm to egg plasma membrane (GO:0007342)7.15995856
7regulation of cilium movement (GO:0003352)6.90833541
8GTP biosynthetic process (GO:0006183)6.84057598
9primary alcohol catabolic process (GO:0034310)6.76410563
10acrosome reaction (GO:0007340)6.28704172
11piRNA metabolic process (GO:0034587)6.27952978
12vitamin transmembrane transport (GO:0035461)6.25636261
13multicellular organism reproduction (GO:0032504)6.18925588
14spermatid development (GO:0007286)6.17373411
15nucleoside diphosphate phosphorylation (GO:0006165)6.16259201
16male meiosis I (GO:0007141)6.11909982
17acrosome assembly (GO:0001675)6.07514965
18UTP biosynthetic process (GO:0006228)5.81611576
19ethanol metabolic process (GO:0006067)5.78483291
20sperm-egg recognition (GO:0035036)5.67755275
21intraciliary transport (GO:0042073)5.53718897
22diterpenoid biosynthetic process (GO:0016102)5.53571203
23plasma membrane fusion (GO:0045026)5.49203315
24male meiosis (GO:0007140)5.44637264
25binding of sperm to zona pellucida (GO:0007339)5.23525977
26single fertilization (GO:0007338)5.12791435
27UTP metabolic process (GO:0046051)5.02657987
28left/right axis specification (GO:0070986)5.02435907
29one-carbon compound transport (GO:0019755)4.95442048
30cell-cell recognition (GO:0009988)4.91187338
31glomerular epithelial cell development (GO:0072310)4.90921195
32cilium organization (GO:0044782)4.85525466
33reproduction (GO:0000003)4.78892606
34pyrimidine-containing compound transmembrane transport (GO:0072531)4.78079220
35tolerance induction (GO:0002507)4.77583664
36lung epithelium development (GO:0060428)4.75291980
37negative regulation of inclusion body assembly (GO:0090084)4.74650187
38establishment of apical/basal cell polarity (GO:0035089)4.71764878
39regulation of interleukin-5 production (GO:0032674)4.64797590
40synaptonemal complex organization (GO:0070193)4.64079412
41cilium assembly (GO:0042384)4.61894589
42response to xenobiotic stimulus (GO:0009410)4.61443429
43cell wall macromolecule metabolic process (GO:0044036)4.60851814
44cell wall macromolecule catabolic process (GO:0016998)4.60851814
45meiosis I (GO:0007127)4.60212814
46protein localization to cilium (GO:0061512)4.58889602
47microtubule polymerization or depolymerization (GO:0031109)4.58438573
48regulation of interleukin-13 production (GO:0032656)4.39416371
49fertilization (GO:0009566)4.37157544
50CTP metabolic process (GO:0046036)4.31959026
51CTP biosynthetic process (GO:0006241)4.31959026
52negative regulation of T cell differentiation in thymus (GO:0033085)4.31388162
53ethanol oxidation (GO:0006069)4.31329645
54regulation of microtubule-based movement (GO:0060632)4.27966017
55negative regulation of B cell mediated immunity (GO:0002713)4.24716630
56negative regulation of immunoglobulin mediated immune response (GO:0002890)4.24716630
57guanosine-containing compound biosynthetic process (GO:1901070)4.18316938
58DNA methylation involved in gamete generation (GO:0043046)4.15516726
59left/right pattern formation (GO:0060972)4.14147765
60establishment or maintenance of monopolar cell polarity (GO:0061339)4.11275290
61establishment of monopolar cell polarity (GO:0061162)4.11275290
62cilium morphogenesis (GO:0060271)4.09910088
63cellular component assembly involved in morphogenesis (GO:0010927)4.05721382
64sperm capacitation (GO:0048240)3.98480677
65negative regulation of humoral immune response (GO:0002921)3.94972238
66negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.91735885
67microtubule bundle formation (GO:0001578)3.90092816
68positive regulation of tolerance induction (GO:0002645)3.83547197
69microtubule-based movement (GO:0007018)3.83448999
70spermatogenesis (GO:0007283)3.77158086
71male gamete generation (GO:0048232)3.75585954
72meiotic cell cycle (GO:0051321)3.75458925
73regulation of germinal center formation (GO:0002634)3.75330090
74cytoplasmic microtubule organization (GO:0031122)3.74976666
75pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.73638515
76terpenoid biosynthetic process (GO:0016114)3.73466765
77retinoic acid metabolic process (GO:0042573)3.72857665
78synaptonemal complex assembly (GO:0007130)3.61645731
79centriole assembly (GO:0098534)3.60120939
80microtubule severing (GO:0051013)3.60097611
81protein polyglutamylation (GO:0018095)3.54791758
82regulation of inclusion body assembly (GO:0090083)3.54577252
83lateral ventricle development (GO:0021670)3.50218632
84gamete generation (GO:0007276)3.48857950
85establishment of tissue polarity (GO:0007164)3.37818765
86establishment of planar polarity (GO:0001736)3.37818765
87germ cell development (GO:0007281)3.33010734
88axon ensheathment in central nervous system (GO:0032291)3.31803820
89central nervous system myelination (GO:0022010)3.31803820
90centriole replication (GO:0007099)3.29081188
91meiotic nuclear division (GO:0007126)3.28991008
92pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.27421640
93positive regulation of meiosis (GO:0045836)3.21942208
94exogenous drug catabolic process (GO:0042738)3.18943497
95retinol metabolic process (GO:0042572)3.17691797
96synapsis (GO:0007129)3.16428116
97spermatid nucleus differentiation (GO:0007289)3.16206735
98phosphatidylethanolamine biosynthetic process (GO:0006646)3.15607489
99primary alcohol metabolic process (GO:0034308)3.15469624
100positive regulation of meiotic cell cycle (GO:0051446)3.14439886
101nucleotide phosphorylation (GO:0046939)3.14210759
102chromosome organization involved in meiosis (GO:0070192)3.10362786
103O-glycan processing (GO:0016266)3.10231408
104pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.09150354
105cell projection assembly (GO:0030031)3.05066942
106calcium ion-dependent exocytosis (GO:0017156)3.03112534
107positive regulation of smoothened signaling pathway (GO:0045880)3.02821274
108cellular process involved in reproduction in multicellular organism (GO:0022412)3.02483756
109regulation of pigment cell differentiation (GO:0050932)3.01340410
110cell recognition (GO:0008037)2.97155415
111organic cation transport (GO:0015695)2.94148300
112nucleoside diphosphate metabolic process (GO:0009132)2.92194960
113microtubule depolymerization (GO:0007019)2.91771884
114glutathione derivative biosynthetic process (GO:1901687)2.90746759
115glutathione derivative metabolic process (GO:1901685)2.90746759
116microtubule-based process (GO:0007017)2.90028075
117otic vesicle formation (GO:0030916)2.88986177
118phosphatidylethanolamine metabolic process (GO:0046337)2.87658794
119seminiferous tubule development (GO:0072520)2.81499811
120regulation of tolerance induction (GO:0002643)2.80917901
121regulation of microtubule depolymerization (GO:0031114)2.79145865
122retinal rod cell development (GO:0046548)2.78569464
123multicellular organismal reproductive process (GO:0048609)2.75931447
124hydrogen peroxide biosynthetic process (GO:0050665)2.74851054
125purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.74275697
126determination of bilateral symmetry (GO:0009855)2.73776936
127organelle assembly (GO:0070925)2.72282721
128smoothened signaling pathway (GO:0007224)2.71774349
129specification of symmetry (GO:0009799)2.67932888
130nonmotile primary cilium assembly (GO:0035058)2.67585058
131phosphatidylcholine biosynthetic process (GO:0006656)2.65847364
132carnitine metabolic process (GO:0009437)2.64352578
133purine nucleoside triphosphate biosynthetic process (GO:0009145)2.63089629
134excretion (GO:0007588)2.61856931
135limb bud formation (GO:0060174)2.61133825
136aldehyde catabolic process (GO:0046185)2.60280660
137multicellular organismal water homeostasis (GO:0050891)2.55784451
138photoreceptor cell differentiation (GO:0046530)2.55109674
139eye photoreceptor cell differentiation (GO:0001754)2.55109674
140Sertoli cell development (GO:0060009)2.54725612
141regulation of meiosis I (GO:0060631)2.52235514
142regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.50594280
143regulation of cilium assembly (GO:1902017)2.49094743
144regulation of cytokine production involved in inflammatory response (GO:1900015)2.47827642
145apical protein localization (GO:0045176)2.47093164
146pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.46825727
147genitalia morphogenesis (GO:0035112)2.46630094
148regulation of response to osmotic stress (GO:0047484)2.46414485
149determination of left/right symmetry (GO:0007368)2.46148048
150drug catabolic process (GO:0042737)2.45717330
151deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.45463510
152phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.44746256
153protein refolding (GO:0042026)2.44487030
154embryonic camera-type eye development (GO:0031076)2.43366627
155doxorubicin metabolic process (GO:0044598)2.42590316
156reactive oxygen species biosynthetic process (GO:1903409)2.42077714
157lateral sprouting from an epithelium (GO:0060601)2.38196775
158hydrogen peroxide catabolic process (GO:0042744)2.37641108
159cilium or flagellum-dependent cell motility (GO:0001539)13.2765764
160axonemal dynein complex assembly (GO:0070286)12.4633089
161cilium movement (GO:0003341)12.2724722
162epithelial cilium movement (GO:0003351)10.9697629

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.60440916
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.98343361
3DROSHA_22980978_ChIP-Seq_HELA_Human3.58092301
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.36380925
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.25110854
6FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.93920708
7TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.65428054
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.44926645
9VDR_22108803_ChIP-Seq_LS180_Human2.28153029
10BMI1_23680149_ChIP-Seq_NPCS_Mouse2.19103962
11PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.14811435
12CBX2_27304074_Chip-Seq_ESCs_Mouse2.12237905
13RNF2_27304074_Chip-Seq_NSC_Mouse2.09861527
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.09667878
15SMC4_20622854_ChIP-Seq_HELA_Human2.03829261
16TRIM28_21343339_ChIP-Seq_HEK293_Human1.98866757
17FLI1_27457419_Chip-Seq_LIVER_Mouse1.96861085
18CTBP2_25329375_ChIP-Seq_LNCAP_Human1.90417734
19PCGF2_27294783_Chip-Seq_ESCs_Mouse1.89685319
20RUNX1_27514584_Chip-Seq_MCF-7_Human1.87269238
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.85967337
22GBX2_23144817_ChIP-Seq_PC3_Human1.81680321
23TAF15_26573619_Chip-Seq_HEK293_Human1.77242451
24ZFP57_27257070_Chip-Seq_ESCs_Mouse1.76900534
25CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76359818
26STAT1_20625510_ChIP-Seq_HELA_Human1.75458593
27AHR_22903824_ChIP-Seq_MCF-7_Human1.75102341
28ESR1_20079471_ChIP-ChIP_T-47D_Human1.74729793
29RBPJ_22232070_ChIP-Seq_NCS_Mouse1.73317008
30TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.72298270
31ELF1_20517297_ChIP-Seq_JURKAT_Human1.71057934
32TP63_22573176_ChIP-Seq_HFKS_Human1.70714800
33GATA1_26923725_Chip-Seq_HPCs_Mouse1.70529675
34ARNT_22903824_ChIP-Seq_MCF-7_Human1.67374943
35EZH2_27304074_Chip-Seq_ESCs_Mouse1.64250922
36ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.63373153
37KLF5_25053715_ChIP-Seq_YYC3_Human1.58279385
38TP63_23658742_ChIP-Seq_EP156T_Human1.57979995
39TDRD3_21172665_ChIP-Seq_MCF-7_Human1.56987570
40SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.56879656
41FUS_26573619_Chip-Seq_HEK293_Human1.56826976
42SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.56632396
43JARID2_20064375_ChIP-Seq_MESCs_Mouse1.56304128
44SOX2_27498859_Chip-Seq_STOMACH_Mouse1.55757928
45FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.55518654
46CTCF_27219007_Chip-Seq_Bcells_Human1.54166720
47P63_26484246_Chip-Seq_KERATINOCYTES_Human1.51502148
48ESR2_21235772_ChIP-Seq_MCF-7_Human1.51131448
49SUZ12_27294783_Chip-Seq_ESCs_Mouse1.50575739
50EZH2_27294783_Chip-Seq_ESCs_Mouse1.50498743
51TP53_18474530_ChIP-ChIP_U2OS_Human1.49278978
52SMAD4_21799915_ChIP-Seq_A2780_Human1.48504274
53BP1_19119308_ChIP-ChIP_Hs578T_Human1.46885532
54ETV1_20927104_ChIP-Seq_GIST48_Human1.46089771
55POU3F2_20337985_ChIP-ChIP_501MEL_Human1.45820927
56RAD21_21589869_ChIP-Seq_MESCs_Mouse1.45262147
57GATA1_19941826_ChIP-Seq_K562_Human1.45190771
58P68_20966046_ChIP-Seq_HELA_Human1.44899470
59SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.44245380
60PCGF2_27294783_Chip-Seq_NPCs_Mouse1.43871612
61SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.43589999
62CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.43514007
63P300_19829295_ChIP-Seq_ESCs_Human1.42731567
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.42654579
65YY1_22570637_ChIP-Seq_MALME-3M_Human1.42622687
66REST_21632747_ChIP-Seq_MESCs_Mouse1.41940806
67CTCF_20526341_ChIP-Seq_ESCs_Human1.41633343
68FOXM1_26456572_ChIP-Seq_MCF-7_Human1.40633833
69SUZ12_27294783_Chip-Seq_NPCs_Mouse1.39366366
70TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39280245
71CTNNB1_20460455_ChIP-Seq_HCT116_Human1.39258810
72NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.39139178
73HNFA_21074721_ChIP-Seq_CACO-2_Human1.38937571
74SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.38830727
75CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.38326530
76AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.37564793
77PHF8_20622853_ChIP-Seq_HELA_Human1.36599407
78ZNF217_24962896_ChIP-Seq_MCF-7_Human1.35334512
79STAT6_21828071_ChIP-Seq_BEAS2B_Human1.35257728
80SOX9_24532713_ChIP-Seq_HFSC_Mouse1.34863162
81NANOG_18555785_Chip-Seq_ESCs_Mouse1.34790722
82PHF8_20622854_ChIP-Seq_HELA_Human1.34575369
83CDX2_19796622_ChIP-Seq_MESCs_Mouse1.33673163
84MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.33542450
85SMRT_27268052_Chip-Seq_Bcells_Human1.33534249
86TAL1_26923725_Chip-Seq_HPCs_Mouse1.33194761
87PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.32948360
88SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.31778916
89JARID2_20075857_ChIP-Seq_MESCs_Mouse1.29556260
90SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29515581
91SMAD3_21741376_ChIP-Seq_EPCs_Human1.29439036
92NR3C1_21868756_ChIP-Seq_MCF10A_Human1.28443118
93EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.28011860
94MTF2_20144788_ChIP-Seq_MESCs_Mouse1.27828192
95TOP2B_26459242_ChIP-Seq_MCF-7_Human1.27528126
96KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.27160186
97KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.27160186
98KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.27160186
99SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.27121677
100RBPJ_21746931_ChIP-Seq_IB4_Human1.26700313
101RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.26439510
102RNF2_27304074_Chip-Seq_ESCs_Mouse1.26048657
103EED_16625203_ChIP-ChIP_MESCs_Mouse1.25568357
104ER_23166858_ChIP-Seq_MCF-7_Human1.25478143
105NFE2_27457419_Chip-Seq_LIVER_Mouse1.25148794
106EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.23895051
107POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.23636567
108TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23636567
109CBX2_22325352_ChIP-Seq_293T-Rex_Human1.21517342
110RNF2_18974828_ChIP-Seq_MESCs_Mouse1.20606957
111EZH2_18974828_ChIP-Seq_MESCs_Mouse1.20606957
112TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19783541
113LXR_22292898_ChIP-Seq_THP-1_Human1.19313112
114BCAT_22108803_ChIP-Seq_LS180_Human1.18926390
115VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.18531550
116UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18422253
117MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.18233041
118CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.18231440
119TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.17572499
120KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.17153679
121ESR1_21235772_ChIP-Seq_MCF-7_Human1.17098658
122GATA6_21074721_ChIP-Seq_CACO-2_Human1.16674238
123MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15510352
124SUZ12_18555785_Chip-Seq_ESCs_Mouse1.15327904
125P300_27268052_Chip-Seq_Bcells_Human1.15054980
126E2F1_20622854_ChIP-Seq_HELA_Human1.14463786
127PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.14384486
128KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.14378480
129CBP_20019798_ChIP-Seq_JUKART_Human1.13747060
130IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.13747060
131CEBPB_22108803_ChIP-Seq_LS180_Human1.13276364
132STAT3_18555785_Chip-Seq_ESCs_Mouse1.12281837
133GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.12232536
134CMYC_18555785_Chip-Seq_ESCs_Mouse1.12069988
135EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.11302402
136NFYA_21822215_ChIP-Seq_K562_Human1.10907552
137P53_22387025_ChIP-Seq_ESCs_Mouse1.10833784
138PIAS1_25552417_ChIP-Seq_VCAP_Human1.10562865
139P300_18555785_Chip-Seq_ESCs_Mouse1.10098354
140CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09786171
141RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09601778
142FOXA1_25552417_ChIP-Seq_VCAP_Human1.09415508
143E2F1_18555785_Chip-Seq_ESCs_Mouse1.08965771
144NFYB_21822215_ChIP-Seq_K562_Human1.08952548
145ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.08805009
146EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.08663847
147IKZF1_21737484_ChIP-ChIP_HCT116_Human1.08284720
148BCOR_27268052_Chip-Seq_Bcells_Human1.08174051
149SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08082704
150CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.07372429
151SMAD4_21741376_ChIP-Seq_EPCs_Human1.07277414
152TBL1_22424771_ChIP-Seq_293T_Human1.07127932
153EZH2_27294783_Chip-Seq_NPCs_Mouse1.05638218
154CREB1_26743006_Chip-Seq_LNCaP_Human1.05232772
155SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.05128042
156OCT4_18555785_Chip-Seq_ESCs_Mouse1.05067144
157WDR5_24793694_ChIP-Seq_LNCAP_Human1.04856546
158CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.04488909
159TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.03681602
160KLF4_18555785_Chip-Seq_ESCs_Mouse1.03032947
161ZFX_18555785_Chip-Seq_ESCs_Mouse1.02562435
162SOX2_18555785_Chip-Seq_ESCs_Mouse1.02044507
163RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.01150395
164PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00741164
165GATA4_25053715_ChIP-Seq_YYC3_Human1.00219397
166IRF1_19129219_ChIP-ChIP_H3396_Human1.00029628
167SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.00013853
168BCL6_27268052_Chip-Seq_Bcells_Human0.99681293
169KDM2B_26808549_Chip-Seq_REH_Human0.99188291
170SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.98716180
171RUNX2_22187159_ChIP-Seq_PCA_Human0.98661552
172CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.98563768
173RACK7_27058665_Chip-Seq_MCF-7_Human0.98409112
174SOX2_20726797_ChIP-Seq_SW620_Human0.98185229
175PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.97753024
176RUNX1_27457419_Chip-Seq_LIVER_Mouse0.97717884
177SOX2_21211035_ChIP-Seq_LN229_Human0.96300287
178P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.95629544
179EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.95321592
180OCT4_20526341_ChIP-Seq_ESCs_Human0.95251108
181CDX2_20551321_ChIP-Seq_CACO-2_Human0.94488479
182MYC_19829295_ChIP-Seq_ESCs_Human0.94384897
183ERG_20517297_ChIP-Seq_VCAP_Human0.93727679
184STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.90577986
185GATA2_19941826_ChIP-Seq_K562_Human0.90279875
186FOXA2_19822575_ChIP-Seq_HepG2_Human0.89681331
187SA1_27219007_Chip-Seq_ERYTHROID_Human0.89533262
188GATA3_24758297_ChIP-Seq_MCF-7_Human0.89407829

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization7.72596656
2MP0008875_abnormal_xenobiotic_pharmacok6.59073146
3MP0003136_yellow_coat_color5.46558863
4MP0004043_abnormal_pH_regulation3.69759789
5MP0003878_abnormal_ear_physiology3.51121252
6MP0005377_hearing/vestibular/ear_phenot3.51121252
7MP0009780_abnormal_chondrocyte_physiolo3.41983987
8MP0003698_abnormal_male_reproductive3.23757696
9MP0005623_abnormal_meninges_morphology3.01389452
10MP0008789_abnormal_olfactory_epithelium2.95312809
11MP0001929_abnormal_gametogenesis2.70514178
12MP0000566_synostosis2.66319991
13MP0002653_abnormal_ependyma_morphology2.64675449
14MP0003880_abnormal_central_pattern2.56706411
15MP0004381_abnormal_hair_follicle2.51257525
16MP0009046_muscle_twitch2.35968386
17MP0005083_abnormal_biliary_tract2.20978672
18MP0009379_abnormal_foot_pigmentation2.15261989
19MP0002160_abnormal_reproductive_system2.14926179
20MP0000678_abnormal_parathyroid_gland2.12413274
21MP0004019_abnormal_vitamin_homeostasis2.06851631
22MP0002210_abnormal_sex_determination1.99381738
23MP0005379_endocrine/exocrine_gland_phen1.98244457
24MP0002168_other_aberrant_phenotype1.95925520
25MP0008004_abnormal_stomach_pH1.94632252
26MP0005409_darkened_coat_color1.84491146
27MP0003656_abnormal_erythrocyte_physiolo1.84294757
28MP0001440_abnormal_grooming_behavior1.80500102
29MP0006276_abnormal_autonomic_nervous1.80209482
30MP0003011_delayed_dark_adaptation1.67218150
31MP0002736_abnormal_nociception_after1.66102835
32MP0006292_abnormal_olfactory_placode1.65256574
33MP0002102_abnormal_ear_morphology1.64694413
34MP0002277_abnormal_respiratory_mucosa1.62840806
35MP0002282_abnormal_trachea_morphology1.61192274
36MP0001968_abnormal_touch/_nociception1.60604012
37MP0008877_abnormal_DNA_methylation1.58052089
38MP0001986_abnormal_taste_sensitivity1.57663910
39MP0001188_hyperpigmentation1.57562441
40MP0001984_abnormal_olfaction1.56970677
41MP0002161_abnormal_fertility/fecundity1.56703492
42MP0001145_abnormal_male_reproductive1.56546943
43MP0010678_abnormal_skin_adnexa1.54065799
44MP0001486_abnormal_startle_reflex1.53229349
45MP0003938_abnormal_ear_development1.51020932
46MP0002163_abnormal_gland_morphology1.49077856
47MP0002572_abnormal_emotion/affect_behav1.44732815
48MP0003122_maternal_imprinting1.43976004
49MP0004270_analgesia1.43517597
50MP0005395_other_phenotype1.43154322
51MP0001501_abnormal_sleep_pattern1.42175777
52MP0002272_abnormal_nervous_system1.41568414
53MP0004133_heterotaxia1.40725489
54MP0002249_abnormal_larynx_morphology1.36758112
55MP0009745_abnormal_behavioral_response1.36376517
56MP0001905_abnormal_dopamine_level1.35386507
57MP0002734_abnormal_mechanical_nocicepti1.34090213
58MP0002064_seizures1.32712858
59MP0000049_abnormal_middle_ear1.32586265
60MP0001346_abnormal_lacrimal_gland1.32299316
61MP0005636_abnormal_mineral_homeostasis1.31147448
62MP0000653_abnormal_sex_gland1.31021897
63MP0002909_abnormal_adrenal_gland1.26782489
64MP0005248_abnormal_Harderian_gland1.25162378
65MP0008057_abnormal_DNA_replication1.24080201
66MP0000778_abnormal_nervous_system1.23241500
67MP0009250_abnormal_appendicular_skeleto1.18617233
68MP0003635_abnormal_synaptic_transmissio1.17458391
69MP0005165_increased_susceptibility_to1.16851190
70MP0004142_abnormal_muscle_tone1.15620139
71MP0005389_reproductive_system_phenotype1.14886948
72MP0005075_abnormal_melanosome_morpholog1.13292675
73MP0000631_abnormal_neuroendocrine_gland1.11489893
74MP0002938_white_spotting1.10571681
75MP0004742_abnormal_vestibular_system1.08027466
76MP0002557_abnormal_social/conspecific_i1.07931857
77MP0005551_abnormal_eye_electrophysiolog1.06331707
78MP0001849_ear_inflammation1.02391082
79MP0002063_abnormal_learning/memory/cond0.99863631
80MP0010234_abnormal_vibrissa_follicle0.97611381
81MP0000681_abnormal_thyroid_gland0.96737183
82MP0002254_reproductive_system_inflammat0.96272677
83MP0006072_abnormal_retinal_apoptosis0.95791791
84MP0000762_abnormal_tongue_morphology0.95693902
85MP0000026_abnormal_inner_ear0.95662663
86MP0005253_abnormal_eye_physiology0.94997611
87MP0005646_abnormal_pituitary_gland0.94779810
88MP0005164_abnormal_response_to0.91111739
89MP0002067_abnormal_sensory_capabilities0.89931178
90MP0001348_abnormal_lacrimal_gland0.88999336
91MP0009643_abnormal_urine_homeostasis0.87941657
92MP0002735_abnormal_chemical_nociception0.87259715
93MP0010030_abnormal_orbit_morphology0.86936965
94MP0001970_abnormal_pain_threshold0.86904427
95MP0005423_abnormal_somatic_nervous0.86771840
96MP0005408_hypopigmentation0.85267497
97MP0001963_abnormal_hearing_physiology0.85131498
98MP0001765_abnormal_ion_homeostasis0.84345496
99MP0005310_abnormal_salivary_gland0.83837718
100MP0010155_abnormal_intestine_physiology0.83329169
101MP0003950_abnormal_plasma_membrane0.82109930
102MP0002136_abnormal_kidney_physiology0.81526412
103MP0005394_taste/olfaction_phenotype0.81390631
104MP0005499_abnormal_olfactory_system0.81390631
105MP0002752_abnormal_somatic_nervous0.80670958
106MP0001270_distended_abdomen0.79404865
107MP0004264_abnormal_extraembryonic_tissu0.79286373
108MP0002332_abnormal_exercise_endurance0.78143413
109MP0003937_abnormal_limbs/digits/tail_de0.77926856
110MP0005365_abnormal_bile_salt0.77913439
111MP0002233_abnormal_nose_morphology0.77346243
112MP0001485_abnormal_pinna_reflex0.76212245
113MP0003303_peritoneal_inflammation0.73457169
114MP0003634_abnormal_glial_cell0.73249747
115MP0004883_abnormal_blood_vessel0.72424588
116MP0000383_abnormal_hair_follicle0.72173633
117MP0002733_abnormal_thermal_nociception0.70781970
118MP0010386_abnormal_urinary_bladder0.70407124
119MP0002132_abnormal_respiratory_system0.70081309
120MP0000920_abnormal_myelination0.69651157
121MP0002184_abnormal_innervation0.68599655
122MP0002638_abnormal_pupillary_reflex0.68131623
123MP0003385_abnormal_body_wall0.66863283
124MP0002116_abnormal_craniofacial_bone0.66774373
125MP0005085_abnormal_gallbladder_physiolo0.66728408
126MP0002796_impaired_skin_barrier0.66442886
127MP0000955_abnormal_spinal_cord0.65972446
128MP0000465_gastrointestinal_hemorrhage0.65664756
129MP0003942_abnormal_urinary_system0.65657762
130MP0000467_abnormal_esophagus_morphology0.65496870
131MP0005645_abnormal_hypothalamus_physiol0.64823883
132MP0002882_abnormal_neuron_morphology0.64667396
133MP0001293_anophthalmia0.62675287
134MP0003718_maternal_effect0.62092186
135MP0005171_absent_coat_pigmentation0.60965718
136MP0009765_abnormal_xenobiotic_induced0.60651133
137MP0002876_abnormal_thyroid_physiology0.59964039
138MP0002177_abnormal_outer_ear0.59851807
139MP0002229_neurodegeneration0.59767543
140MP0001529_abnormal_vocalization0.59752638
141MP0002405_respiratory_system_inflammati0.56717863
142MP0001879_abnormal_lymphatic_vessel0.55318470
143MP0002928_abnormal_bile_duct0.53798173
144MP0005220_abnormal_exocrine_pancreas0.53400258
145MP0003453_abnormal_keratinocyte_physiol0.52875145
146MP0003806_abnormal_nucleotide_metabolis0.52540886
147MP0001299_abnormal_eye_distance/0.52006945
148MP0005670_abnormal_white_adipose0.51559390
149MP0001502_abnormal_circadian_rhythm0.50657182
150MP0001324_abnormal_eye_pigmentation0.49986150
151MP0005503_abnormal_tendon_morphology0.49683900
152MP0001944_abnormal_pancreas_morphology0.48957602
153MP0002098_abnormal_vibrissa_morphology0.47266142
154MP0003879_abnormal_hair_cell0.46210181
155MP0002139_abnormal_hepatobiliary_system0.45944881
156MP0001666_abnormal_nutrient_absorption0.44354397
157MP0006082_CNS_inflammation0.44264006
158MP0009763_increased_sensitivity_to0.44255707
159MP0002135_abnormal_kidney_morphology0.43966837
160MP0002822_catalepsy0.43229330
161MP0005391_vision/eye_phenotype0.42919473
162MP0002896_abnormal_bone_mineralization0.42908930

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)9.77945329
2Absent/shortened dynein arms (HP:0200106)9.77945329
3Abnormal respiratory motile cilium morphology (HP:0005938)8.78331216
4Abnormal respiratory epithelium morphology (HP:0012253)8.78331216
5Rhinitis (HP:0012384)8.63362867
6Chronic bronchitis (HP:0004469)6.40163631
7Nasal polyposis (HP:0100582)5.37337117
8Bronchiectasis (HP:0002110)4.96681743
9Abnormality of the nasal mucosa (HP:0000433)4.36890472
10Infertility (HP:0000789)4.21860402
11Nephronophthisis (HP:0000090)4.01244589
12Bronchitis (HP:0012387)3.38390003
13True hermaphroditism (HP:0010459)3.30097256
14Abnormality of midbrain morphology (HP:0002418)3.28088213
15Molar tooth sign on MRI (HP:0002419)3.28088213
16Chronic sinusitis (HP:0011109)3.20809771
17Pancreatic fibrosis (HP:0100732)3.13010067
18Supernumerary spleens (HP:0009799)3.10258900
19Abnormality of the renal medulla (HP:0100957)3.09390278
20Medial flaring of the eyebrow (HP:0010747)3.06797932
21Chronic otitis media (HP:0000389)2.95891887
22Tubulointerstitial nephritis (HP:0001970)2.93606452
23Recurrent sinusitis (HP:0011108)2.82221614
24Hyperactive renin-angiotensin system (HP:0000841)2.75458806
25Gait imbalance (HP:0002141)2.43817636
26Congenital primary aphakia (HP:0007707)2.39412224
27Congenital hepatic fibrosis (HP:0002612)2.39085808
28Pancreatic cysts (HP:0001737)2.38556793
29Tubular atrophy (HP:0000092)2.37624338
30Abnormality of dentin (HP:0010299)2.34540939
31Concave nail (HP:0001598)2.25567210
32Occipital encephalocele (HP:0002085)2.24803861
33Abnormality of the dental root (HP:0006486)2.21428775
34Taurodontia (HP:0000679)2.21428775
35Abnormality of permanent molar morphology (HP:0011071)2.21428775
36Postaxial foot polydactyly (HP:0001830)2.21070579
37Median cleft lip (HP:0000161)2.20256872
38Recurrent otitis media (HP:0000403)2.19099428
39Stage 5 chronic kidney disease (HP:0003774)2.15713036
40Atelectasis (HP:0100750)2.15606496
41Abnormality of molar morphology (HP:0011070)2.13305324
42Abnormality of molar (HP:0011077)2.13305324
43Fibular hypoplasia (HP:0003038)2.10876496
44Nephrogenic diabetes insipidus (HP:0009806)2.08278089
45Genital tract atresia (HP:0001827)2.01581981
46Abnormality of the dental pulp (HP:0006479)2.01000039
47Anencephaly (HP:0002323)2.00868817
48Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.4702549
49Abnormal respiratory motile cilium physiology (HP:0012261)10.7985281
50Abnormal ciliary motility (HP:0012262)10.1649407
51Abnormal biliary tract physiology (HP:0012439)1.97086719
52Bile duct proliferation (HP:0001408)1.97086719
53Abnormal sex determination (HP:0012244)1.96659651
54Sex reversal (HP:0012245)1.96659651
55Vaginal atresia (HP:0000148)1.95511257
56Cystic liver disease (HP:0006706)1.91573526
57Hyperkalemia (HP:0002153)1.90534498
58Aplasia/Hypoplasia of the lens (HP:0008063)1.87521856
59Tubulointerstitial abnormality (HP:0001969)1.86149541
60Aplasia/Hypoplasia of the tongue (HP:0010295)1.84725007
61Postaxial hand polydactyly (HP:0001162)1.82913933
62Absent frontal sinuses (HP:0002688)1.81967324
63Male pseudohermaphroditism (HP:0000037)1.81478774
64Oculomotor apraxia (HP:0000657)1.81296448
65Chronic hepatic failure (HP:0100626)1.79932427
66Male infertility (HP:0003251)1.72122658
67Renal salt wasting (HP:0000127)1.68117475
68Preaxial hand polydactyly (HP:0001177)1.65587319
69Abnormal drinking behavior (HP:0030082)1.64830797
70Polydipsia (HP:0001959)1.64830797
71Decreased circulating renin level (HP:0003351)1.63523250
72Sclerocornea (HP:0000647)1.63325200
73Poor coordination (HP:0002370)1.61023506
74Asplenia (HP:0001746)1.59467007
75Aplasia/Hypoplasia of the spleen (HP:0010451)1.58951782
76Facial cleft (HP:0002006)1.55830222
77Bifid tongue (HP:0010297)1.51738024
78Hyperventilation (HP:0002883)1.51355208
79Furrowed tongue (HP:0000221)1.46315364
80Hemiparesis (HP:0001269)1.44740832
81Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.44522467
82Cone-rod dystrophy (HP:0000548)1.44434459
83Nephroblastoma (Wilms tumor) (HP:0002667)1.44029692
8411 pairs of ribs (HP:0000878)1.43194592
85Bell-shaped thorax (HP:0001591)1.42280517
86Embryonal renal neoplasm (HP:0011794)1.41641216
87Hypodontia (HP:0000668)1.38781559
88Abnormality of chloride homeostasis (HP:0011422)1.37401426
89Recurrent bronchitis (HP:0002837)1.37207585
90Aplasia/Hypoplasia of the fibula (HP:0006492)1.36486910
91Hyperaldosteronism (HP:0000859)1.34868880
92Absent rod-and cone-mediated responses on ERG (HP:0007688)1.33173062
93Renal dysplasia (HP:0000110)1.33141615
94Short nail (HP:0001799)1.32985724
95Abnormality of renal resorption (HP:0011038)1.31799978
96Aganglionic megacolon (HP:0002251)1.29859194
97Abdominal situs inversus (HP:0003363)1.29346099
98Abnormality of abdominal situs (HP:0011620)1.29346099
99Focal motor seizures (HP:0011153)1.28887059
100Partial duplication of thumb phalanx (HP:0009944)1.28838189
101Abnormality of the renal cortex (HP:0011035)1.27490260
102Hyponatremia (HP:0002902)1.26438278
103Hand muscle atrophy (HP:0009130)1.26283528
104Neurofibrillary tangles (HP:0002185)1.26217751
105Impaired proprioception (HP:0010831)1.24309787
106Nephropathy (HP:0000112)1.24287771
107Short thorax (HP:0010306)1.23103855
108Transposition of the great arteries (HP:0001669)1.22450185
109Abnormal connection of the cardiac segments (HP:0011545)1.22450185
110Abnormal ventriculo-arterial connection (HP:0011563)1.22450185
111Epileptic encephalopathy (HP:0200134)1.21888891
112Nasolacrimal duct obstruction (HP:0000579)1.21014533
113Abnormality of macular pigmentation (HP:0008002)1.20826823
114Abnormality of renin-angiotensin system (HP:0000847)1.20351517
115Retinal dysplasia (HP:0007973)1.19863742
116Glucose intolerance (HP:0000833)1.19589580
117Decreased central vision (HP:0007663)1.19304633
118Fetal akinesia sequence (HP:0001989)1.17011881
119Ectopic anus (HP:0004397)1.16096169
120Multicystic kidney dysplasia (HP:0000003)1.14363660
121Progressive inability to walk (HP:0002505)1.13999982
122Missing ribs (HP:0000921)1.13904437
123Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.13695041
124Abnormality of the frontal sinuses (HP:0002687)1.12181859
125Abnormality of the distal phalanges of the toes (HP:0010182)1.11242515
126Abnormal rod and cone electroretinograms (HP:0008323)1.11179588
127Hypokalemic alkalosis (HP:0001949)1.08183964
128Aplasia of the musculature (HP:0100854)1.06341895
129Bifid scrotum (HP:0000048)1.03377673
130Short femoral neck (HP:0100864)1.03012932
131Popliteal pterygium (HP:0009756)0.99747776
132Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)0.97993028
133Abnormality of sodium homeostasis (HP:0010931)0.95405169
134Obstructive sleep apnea (HP:0002870)0.93749463
135Portal hypertension (HP:0001409)0.92825158
136Tubulointerstitial fibrosis (HP:0005576)0.92721339
137Retinitis pigmentosa (HP:0000510)0.92683440

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK5.77395676
2EPHA24.54666991
3MAPK154.35379178
4PDK44.03725353
5PDK34.03725353
6PDK23.37984765
7STK392.92770725
8GRK52.91995406
9CASK2.39494404
10GRK72.33625933
11GRK12.21769766
12MAP3K22.15072300
13MAPKAPK32.11403669
14WNK42.09294964
15TESK11.96857769
16PTK2B1.96804209
17SMG11.84926172
18ADRBK21.79573199
19MUSK1.72525114
20MAP3K31.70649663
21IRAK11.66887906
22EEF2K1.65856569
23PRKD31.65457795
24MST1R1.48321898
25MST41.45824281
26STK241.44290639
27CSK1.41040037
28WNK11.36450658
29STK381.29520796
30ICK1.25983299
31TYRO31.20813152
32BMPR1B1.13079393
33EPHA41.12607264
34IRAK21.11884204
35PLK41.09309670
36BMPR21.07800465
37AKT31.05193703
38EPHB11.03887952
39OXSR11.03725111
40MAP3K71.02324144
41NME10.99397910
42NTRK20.98578813
43NEK60.97392503
44NTRK30.97078485
45STK100.95833684
46PBK0.95757576
47LRRK20.93871284
48MAPKAPK50.93343595
49MAP2K70.93074028
50CDK30.92600453
51STK160.91475466
52MOS0.91073884
53ADRBK10.90984860
54TNIK0.89858617
55TRPM70.89818558
56INSRR0.87719093
57PRKCE0.84654112
58BCR0.83272603
59PRKCG0.82979747
60PLK20.81996726
61CDK120.81614959
62VRK10.79047632
63PKN10.78626262
64DYRK30.75921239
65CAMK2A0.73556829
66MKNK20.70973367
67PRKCI0.69650776
68MARK20.69440106
69PDPK10.68698095
70RIPK40.67766413
71TBK10.66190688
72NTRK10.65366952
73TLK10.64734177
74GRK60.64653370
75CAMK2B0.61968534
76BRSK20.61857092
77FES0.61798881
78EPHB20.61422807
79ERBB20.59721231
80STK38L0.58621520
81EPHA30.58599634
82FER0.58501074
83ERBB30.58358191
84YES10.57772987
85MAPK130.57416337
86MAPK70.56331816
87DYRK1A0.55796256
88FGR0.53232983
89CAMKK10.53212645
90TRIB30.51679090
91SIK30.49899115
92TGFBR20.48725595
93SIK20.47967939
94TTK0.47544970
95PRKACA0.47277923
96MAP3K120.46185855
97SGK10.46121147
98WNK30.43462254
99RPS6KB20.43448184
100AURKA0.41929434
101PRKG10.41123894
102PRKG20.41098810
103PRKAA20.40768137
104PINK10.40747876
105DYRK1B0.40729099
106PRKCD0.40219951
107BRD40.38981846
108UHMK10.38422688
109PDK10.38146741
110HIPK20.37906625
111MATK0.37875079
112MAP3K40.37192165
113RPS6KA50.37146958
114DYRK20.36879576
115STK30.35913479
116NLK0.35893142
117RIPK10.35483620
118LATS10.35418692
119PRKCQ0.34834156
120PAK30.34777014
121DDR20.34642374
122MAP4K20.33355558
123ROCK10.33326062
124MET0.32756246
125KSR20.32224837
126CAMK2D0.32104018
127MARK10.32008977
128ARAF0.31819313
129CAMK1G0.31665548
130TSSK60.30390489
131MAP2K20.30340920
132GSK3A0.30203318
133WEE10.30090389
134PRKD20.28860806
135RPS6KA20.28579358
136LMTK20.28140619
137PAK40.26520319
138CAMK2G0.25538695
139SGK2230.25371479
140SGK4940.25371479
141CSNK1E0.25285765
142CDK50.25280162
143MAP2K40.25166288
144EIF2AK20.25054776
145TNK20.24732899
146STK110.22319501
147ROCK20.20745721
148PRKCA0.19476895
149MAP2K10.19431170
150CDC42BPA0.18264099
151PIM20.17252890
152MAP3K80.17244702
153SRC0.16589014
154PAK10.16398281
155TAOK10.15955451
156AKT20.15886214
157CDK190.15215235
158PTK60.13047737
159ABL10.13044337
160CCNB10.12988787
161PLK10.11556982

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003605.17311233
2Tyrosine metabolism_Homo sapiens_hsa003503.91947916
3Huntingtons disease_Homo sapiens_hsa050163.25587517
4Oxidative phosphorylation_Homo sapiens_hsa001903.12766483
5beta-Alanine metabolism_Homo sapiens_hsa004102.92921368
6Vitamin B6 metabolism_Homo sapiens_hsa007502.46241727
7Nicotine addiction_Homo sapiens_hsa050332.36458059
8Alzheimers disease_Homo sapiens_hsa050102.33637026
9Parkinsons disease_Homo sapiens_hsa050122.22116779
10Ether lipid metabolism_Homo sapiens_hsa005652.19609369
11Linoleic acid metabolism_Homo sapiens_hsa005912.19339952
12Caffeine metabolism_Homo sapiens_hsa002322.14692248
13Dorso-ventral axis formation_Homo sapiens_hsa043201.94202502
14Taste transduction_Homo sapiens_hsa047421.92808525
15alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.91293478
16Amphetamine addiction_Homo sapiens_hsa050311.88593943
17Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.84524913
18Collecting duct acid secretion_Homo sapiens_hsa049661.84392711
19Serotonergic synapse_Homo sapiens_hsa047261.83784911
20Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.82186272
21Arachidonic acid metabolism_Homo sapiens_hsa005901.81467767
22Glutamatergic synapse_Homo sapiens_hsa047241.77806765
23Renin secretion_Homo sapiens_hsa049241.77328436
24Cardiac muscle contraction_Homo sapiens_hsa042601.76302787
25Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.74948937
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.71016580
27Sphingolipid metabolism_Homo sapiens_hsa006001.49247686
28Calcium signaling pathway_Homo sapiens_hsa040201.47847740
29Fatty acid degradation_Homo sapiens_hsa000711.47720408
30ABC transporters_Homo sapiens_hsa020101.45345999
31Tight junction_Homo sapiens_hsa045301.45125224
32Long-term potentiation_Homo sapiens_hsa047201.44906502
33GABAergic synapse_Homo sapiens_hsa047271.40041100
34Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.38424575
35Steroid hormone biosynthesis_Homo sapiens_hsa001401.36848130
36African trypanosomiasis_Homo sapiens_hsa051431.36104702
37Circadian entrainment_Homo sapiens_hsa047131.34074238
38Salivary secretion_Homo sapiens_hsa049701.30098321
39Protein export_Homo sapiens_hsa030601.29860737
40Phototransduction_Homo sapiens_hsa047441.27930855
41Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.27607918
42Fanconi anemia pathway_Homo sapiens_hsa034601.25654530
43Long-term depression_Homo sapiens_hsa047301.25551568
44Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.22285045
45Hedgehog signaling pathway_Homo sapiens_hsa043401.14336278
46Rheumatoid arthritis_Homo sapiens_hsa053231.12865911
47Cocaine addiction_Homo sapiens_hsa050301.11574624
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.10183789
49Basal transcription factors_Homo sapiens_hsa030221.09949346
50Morphine addiction_Homo sapiens_hsa050321.08240613
51Dopaminergic synapse_Homo sapiens_hsa047281.05776955
52Vascular smooth muscle contraction_Homo sapiens_hsa042701.03775048
53Peroxisome_Homo sapiens_hsa041461.03665633
54Insulin secretion_Homo sapiens_hsa049111.02799177
55Gastric acid secretion_Homo sapiens_hsa049710.99865944
56Pyruvate metabolism_Homo sapiens_hsa006200.99674343
57Graft-versus-host disease_Homo sapiens_hsa053320.99540639
58Synaptic vesicle cycle_Homo sapiens_hsa047210.97962487
59Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.97515981
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.94684408
61Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.92403347
62Primary bile acid biosynthesis_Homo sapiens_hsa001200.90018838
63Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.89851706
64Wnt signaling pathway_Homo sapiens_hsa043100.89728634
65Glycerophospholipid metabolism_Homo sapiens_hsa005640.89433951
66Mineral absorption_Homo sapiens_hsa049780.89083972
67Vibrio cholerae infection_Homo sapiens_hsa051100.87170162
68Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86706469
69SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86194588
70Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.83933410
71Axon guidance_Homo sapiens_hsa043600.82371100
72Starch and sucrose metabolism_Homo sapiens_hsa005000.82257829
73Fatty acid elongation_Homo sapiens_hsa000620.81005745
74Notch signaling pathway_Homo sapiens_hsa043300.79657399
75cAMP signaling pathway_Homo sapiens_hsa040240.77957236
76Circadian rhythm_Homo sapiens_hsa047100.75973039
77Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.74703007
78Ovarian steroidogenesis_Homo sapiens_hsa049130.73184206
79Glucagon signaling pathway_Homo sapiens_hsa049220.72935353
80Sulfur metabolism_Homo sapiens_hsa009200.72056540
81Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.71792117
82Estrogen signaling pathway_Homo sapiens_hsa049150.71580737
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.69725013
84Choline metabolism in cancer_Homo sapiens_hsa052310.69425626
85Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68956376
86Inositol phosphate metabolism_Homo sapiens_hsa005620.68495521
87Oxytocin signaling pathway_Homo sapiens_hsa049210.68026529
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67969528
89PPAR signaling pathway_Homo sapiens_hsa033200.67003700
90Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66556235
91Melanogenesis_Homo sapiens_hsa049160.66317207
92Ribosome_Homo sapiens_hsa030100.65255347
93Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64980240
94Glutathione metabolism_Homo sapiens_hsa004800.64885113
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64578525
96Adherens junction_Homo sapiens_hsa045200.63289433
97Basal cell carcinoma_Homo sapiens_hsa052170.61568609
98Chemical carcinogenesis_Homo sapiens_hsa052040.59842616
99cGMP-PKG signaling pathway_Homo sapiens_hsa040220.59422157
100Fatty acid biosynthesis_Homo sapiens_hsa000610.59393255
101Olfactory transduction_Homo sapiens_hsa047400.57273344
102Cholinergic synapse_Homo sapiens_hsa047250.56351403
103Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54253600
104Leukocyte transendothelial migration_Homo sapiens_hsa046700.53973571
105Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53705302
106Carbohydrate digestion and absorption_Homo sapiens_hsa049730.53622236
107Glycerolipid metabolism_Homo sapiens_hsa005610.52723788
108Hepatitis C_Homo sapiens_hsa051600.52346931
109Ras signaling pathway_Homo sapiens_hsa040140.51864120
110Arginine and proline metabolism_Homo sapiens_hsa003300.50228809
111Phagosome_Homo sapiens_hsa041450.50011682
112Pancreatic secretion_Homo sapiens_hsa049720.47193860
113Sulfur relay system_Homo sapiens_hsa041220.46788595
114Other glycan degradation_Homo sapiens_hsa005110.46446708
115Thyroid hormone synthesis_Homo sapiens_hsa049180.46160734
116GnRH signaling pathway_Homo sapiens_hsa049120.45316847
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.44610369
118Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.44478647
119Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43420878
120Aldosterone synthesis and secretion_Homo sapiens_hsa049250.42639097
121Retinol metabolism_Homo sapiens_hsa008300.41198889
122Histidine metabolism_Homo sapiens_hsa003400.40810360
123Fructose and mannose metabolism_Homo sapiens_hsa000510.40242543
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.39573124
125Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38724184
126Gap junction_Homo sapiens_hsa045400.35932701
127Metabolic pathways_Homo sapiens_hsa011000.35559569
128Autoimmune thyroid disease_Homo sapiens_hsa053200.35238054
129Hematopoietic cell lineage_Homo sapiens_hsa046400.34542875
130Complement and coagulation cascades_Homo sapiens_hsa046100.34538312
131Butanoate metabolism_Homo sapiens_hsa006500.31467629
132Endocytosis_Homo sapiens_hsa041440.25422233
133Glycosaminoglycan degradation_Homo sapiens_hsa005310.24000173
134Sphingolipid signaling pathway_Homo sapiens_hsa040710.23074189
135Vitamin digestion and absorption_Homo sapiens_hsa049770.22830478
136Amoebiasis_Homo sapiens_hsa051460.21170374
137Hippo signaling pathway_Homo sapiens_hsa043900.19674105
138Jak-STAT signaling pathway_Homo sapiens_hsa046300.19196927
139Type I diabetes mellitus_Homo sapiens_hsa049400.18267347
140Arginine biosynthesis_Homo sapiens_hsa002200.18029056
141Insulin resistance_Homo sapiens_hsa049310.17689742
142Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.16806314
143Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.16026385
144Lysosome_Homo sapiens_hsa041420.15265440
145Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.15042339
146Bile secretion_Homo sapiens_hsa049760.14430507
147Allograft rejection_Homo sapiens_hsa053300.11838612
148Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.11699151
149Prostate cancer_Homo sapiens_hsa052150.11374338
150Antigen processing and presentation_Homo sapiens_hsa046120.10098267
151Cyanoamino acid metabolism_Homo sapiens_hsa004600.09866125
152Type II diabetes mellitus_Homo sapiens_hsa049300.07789298
153Nitrogen metabolism_Homo sapiens_hsa009100.04968199

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