LRRC73

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)8.38756419
2cilium or flagellum-dependent cell motility (GO:0001539)6.63659828
3cilium movement (GO:0003341)6.32820167
4motile cilium assembly (GO:0044458)6.20346309
5regulation of short-term neuronal synaptic plasticity (GO:0048172)5.90345348
6epithelial cilium movement (GO:0003351)5.88597299
7synaptic vesicle maturation (GO:0016188)5.71331781
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.64650221
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.55651617
10locomotory exploration behavior (GO:0035641)5.46631094
11synaptic vesicle exocytosis (GO:0016079)5.22539091
12vocalization behavior (GO:0071625)5.18078690
13positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.16922528
14regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.06443952
15protein localization to synapse (GO:0035418)5.00663598
16glutamate secretion (GO:0014047)5.00330011
17regulation of synaptic vesicle exocytosis (GO:2000300)4.93806011
18regulation of glutamate receptor signaling pathway (GO:1900449)4.67577044
19left/right pattern formation (GO:0060972)4.64069812
20exploration behavior (GO:0035640)4.61214565
21layer formation in cerebral cortex (GO:0021819)4.58188594
22neuron cell-cell adhesion (GO:0007158)4.57465963
23axoneme assembly (GO:0035082)4.38872072
24regulation of synaptic vesicle transport (GO:1902803)4.38159915
25synaptic vesicle docking involved in exocytosis (GO:0016081)4.34994220
26regulation of long-term neuronal synaptic plasticity (GO:0048169)4.30812425
27dendritic spine morphogenesis (GO:0060997)4.29205002
28regulation of neuronal synaptic plasticity (GO:0048168)4.26417646
29ionotropic glutamate receptor signaling pathway (GO:0035235)4.20976012
30neurotransmitter secretion (GO:0007269)4.12236842
31regulation of synapse structural plasticity (GO:0051823)3.96510549
32neuron recognition (GO:0008038)3.92978190
33neuronal action potential propagation (GO:0019227)3.89786968
34lung epithelium development (GO:0060428)3.87678862
35synaptic transmission, glutamatergic (GO:0035249)3.83121191
36microtubule bundle formation (GO:0001578)3.82369002
37gamma-aminobutyric acid transport (GO:0015812)3.79268818
38glutamate receptor signaling pathway (GO:0007215)3.72064725
39positive regulation of synapse maturation (GO:0090129)3.69704782
40regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.69632480
41axonal fasciculation (GO:0007413)3.60840389
42positive regulation of membrane potential (GO:0045838)3.59103485
43proline transport (GO:0015824)3.57203316
44microtubule severing (GO:0051013)3.57197168
45regulation of cilium movement (GO:0003352)3.57173798
46neuron-neuron synaptic transmission (GO:0007270)3.55774023
47regulation of dendritic spine morphogenesis (GO:0061001)3.50436561
48postsynaptic membrane organization (GO:0001941)3.49892507
49regulation of excitatory postsynaptic membrane potential (GO:0060079)3.47018410
50long-term memory (GO:0007616)3.45848339
51activation of protein kinase A activity (GO:0034199)3.45155837
52neurotransmitter-gated ion channel clustering (GO:0072578)3.43913533
53regulation of microtubule-based movement (GO:0060632)3.41105627
54calcium ion-dependent exocytosis (GO:0017156)3.39048870
55positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.38860955
56dendrite morphogenesis (GO:0048813)3.38357755
57protein polyglutamylation (GO:0018095)3.38291750
58regulation of vesicle fusion (GO:0031338)3.36811271
59regulation of synaptic plasticity (GO:0048167)3.36578008
60behavioral response to nicotine (GO:0035095)3.35433387
61transmission of nerve impulse (GO:0019226)3.31865839
62intraciliary transport (GO:0042073)3.30791692
63regulation of postsynaptic membrane potential (GO:0060078)3.29651510
64dendritic spine organization (GO:0097061)3.28792556
65neurotransmitter transport (GO:0006836)3.27681116
66positive regulation of synaptic transmission, GABAergic (GO:0032230)3.26673059
67ventricular system development (GO:0021591)3.22628557
68vesicle transport along microtubule (GO:0047496)3.22073464
69regulation of neurotransmitter secretion (GO:0046928)3.20355917
70synaptic vesicle endocytosis (GO:0048488)3.18336493
71neuromuscular process controlling balance (GO:0050885)3.12230480
72long-term synaptic potentiation (GO:0060291)3.10693166
73auditory behavior (GO:0031223)3.10136323
74protein localization to cilium (GO:0061512)3.09594548
75positive regulation of neurotransmitter secretion (GO:0001956)3.08983382
76regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.08789108
77positive regulation of dendritic spine morphogenesis (GO:0061003)3.08049973
78presynaptic membrane assembly (GO:0097105)3.07742583
79gamma-aminobutyric acid signaling pathway (GO:0007214)3.06167609
80detection of calcium ion (GO:0005513)3.05862176
81phosphorelay signal transduction system (GO:0000160)3.05832436
82organelle transport along microtubule (GO:0072384)3.04671773
83positive regulation of dendritic spine development (GO:0060999)3.03156534
84mating behavior (GO:0007617)3.03031443
85G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.02540146
86cerebellar Purkinje cell layer development (GO:0021680)2.99287089
87regulation of neurotransmitter levels (GO:0001505)2.99279000
88neuronal ion channel clustering (GO:0045161)2.98491680
89cellular potassium ion homeostasis (GO:0030007)2.98389775
90positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.96778147
91regulation of dendritic spine development (GO:0060998)2.95999475
92regulation of calcium ion-dependent exocytosis (GO:0017158)2.95985954
93innervation (GO:0060384)2.93111820
94cell migration in hindbrain (GO:0021535)2.92115285
95negative regulation of synaptic transmission, GABAergic (GO:0032229)2.91798518
96synapse assembly (GO:0007416)2.90657001
97positive regulation of neurotransmitter transport (GO:0051590)2.90520602
98regulation of synaptic transmission, glutamatergic (GO:0051966)2.88431643
99sodium ion export (GO:0071436)2.88088788
100regulation of neurotransmitter transport (GO:0051588)2.87447349
101learning (GO:0007612)2.86995995
102intraspecies interaction between organisms (GO:0051703)2.86174542
103social behavior (GO:0035176)2.86174542
104central nervous system projection neuron axonogenesis (GO:0021952)2.85947002
105negative regulation of microtubule polymerization (GO:0031115)2.85760941
106regulation of female receptivity (GO:0045924)2.85327751
107membrane depolarization (GO:0051899)2.84746090
108response to auditory stimulus (GO:0010996)2.83811629
109membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.83177699
110pyrimidine nucleobase catabolic process (GO:0006208)2.81047947
111presynaptic membrane organization (GO:0097090)2.80614747
112cerebellar granule cell differentiation (GO:0021707)2.80229275
113chemosensory behavior (GO:0007635)2.79478579
114adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.79398210
115regulation of ARF protein signal transduction (GO:0032012)2.77975275
116clathrin coat assembly (GO:0048268)2.77796267
117synapse organization (GO:0050808)2.77731163
118membrane depolarization during action potential (GO:0086010)2.77204236
119neuromuscular synaptic transmission (GO:0007274)2.76889838
120regulation of synaptic transmission (GO:0050804)2.75144432
121apical protein localization (GO:0045176)2.74236913
122establishment or maintenance of monopolar cell polarity (GO:0061339)2.73673696
123establishment of monopolar cell polarity (GO:0061162)2.73673696
124cerebellum development (GO:0021549)2.73213989
125microtubule-based movement (GO:0007018)2.72819576
126regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.72604426
127behavioral defense response (GO:0002209)2.72501155
128behavioral fear response (GO:0001662)2.72501155
129regulation of synapse maturation (GO:0090128)2.71299760
130response to histamine (GO:0034776)2.70439817
131cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.69479145
132sperm capacitation (GO:0048240)2.69110932
133negative regulation of amino acid transport (GO:0051956)2.63758295
134negative regulation of T cell differentiation in thymus (GO:0033085)2.63380366
135regulation of voltage-gated calcium channel activity (GO:1901385)2.63147398
136camera-type eye morphogenesis (GO:0048593)2.60468504
137CDP-diacylglycerol metabolic process (GO:0046341)2.57990719
138cilium organization (GO:0044782)2.57755131
139primary alcohol catabolic process (GO:0034310)2.57385584
140cilium assembly (GO:0042384)2.57355932
141dopamine receptor signaling pathway (GO:0007212)2.55494950
142CDP-diacylglycerol biosynthetic process (GO:0016024)2.55354046
143substrate-independent telencephalic tangential migration (GO:0021826)2.55264660
144substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.55264660
145sensory perception of taste (GO:0050909)2.53556006
146response to parathyroid hormone (GO:0071107)2.53411156
147prepulse inhibition (GO:0060134)2.49407961
148potassium ion homeostasis (GO:0055075)2.49153813
149left/right axis specification (GO:0070986)2.43749250
150adult walking behavior (GO:0007628)2.43482706
151cerebellar Purkinje cell differentiation (GO:0021702)2.43415972
152phenol-containing compound catabolic process (GO:0019336)2.41620687
153body morphogenesis (GO:0010171)2.40629543
154establishment of apical/basal cell polarity (GO:0035089)2.39583597

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.41543603
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat6.15856086
3GBX2_23144817_ChIP-Seq_PC3_Human3.01920322
4REST_21632747_ChIP-Seq_MESCs_Mouse2.99447169
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.91725739
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.73569527
7SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.69660462
8RARB_27405468_Chip-Seq_BRAIN_Mouse2.67221269
9SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.59092479
10MTF2_20144788_ChIP-Seq_MESCs_Mouse2.46652189
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.42485671
12RNF2_18974828_ChIP-Seq_MESCs_Mouse2.40257702
13EZH2_18974828_ChIP-Seq_MESCs_Mouse2.40257702
14DROSHA_22980978_ChIP-Seq_HELA_Human2.38756773
15EZH2_27304074_Chip-Seq_ESCs_Mouse2.36684798
16SUZ12_27294783_Chip-Seq_ESCs_Mouse2.36280668
17SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.36265836
18REST_18959480_ChIP-ChIP_MESCs_Mouse2.35720769
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.34853094
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.29226460
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.24259075
22SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.24001246
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.21128587
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.12195769
25LXR_22292898_ChIP-Seq_THP-1_Human1.99982071
26SRY_22984422_ChIP-ChIP_TESTIS_Rat1.99396609
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.97036223
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.94882007
29IKZF1_21737484_ChIP-ChIP_HCT116_Human1.93721786
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.92968123
31EED_16625203_ChIP-ChIP_MESCs_Mouse1.89282478
32EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.88704265
33P68_20966046_ChIP-Seq_HELA_Human1.88244092
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.83214008
35SMC4_20622854_ChIP-Seq_HELA_Human1.77468679
36ZNF274_21170338_ChIP-Seq_K562_Hela1.71885157
37THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.65846496
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60861942
39SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.57429932
40SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.56544517
41ESR2_21235772_ChIP-Seq_MCF-7_Human1.53875428
42AR_21572438_ChIP-Seq_LNCaP_Human1.53037142
43RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.48081461
44TET1_21451524_ChIP-Seq_MESCs_Mouse1.47055645
45SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.46061007
46SMAD4_21799915_ChIP-Seq_A2780_Human1.45531722
47TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.43821703
48ERG_21242973_ChIP-ChIP_JURKAT_Human1.43085341
49SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.42168206
50CREB1_26743006_Chip-Seq_LNCaP_Human1.40482105
51SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37456704
52ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.35306377
53RING1B_27294783_Chip-Seq_ESCs_Mouse1.34086496
54TAF15_26573619_Chip-Seq_HEK293_Human1.31036395
55KDM2B_26808549_Chip-Seq_SUP-B15_Human1.30155631
56TP53_20018659_ChIP-ChIP_R1E_Mouse1.29470498
57RACK7_27058665_Chip-Seq_MCF-7_Human1.27773505
58CTCF_20526341_ChIP-Seq_ESCs_Human1.27197553
59SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.26619044
60TRIM28_21343339_ChIP-Seq_HEK293_Human1.26366188
61MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.25623131
62PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.24573213
63PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.23717860
64SMAD3_21741376_ChIP-Seq_EPCs_Human1.22973700
65NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21618006
66SOX2_21211035_ChIP-Seq_LN229_Gbm1.20960597
67ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20386682
68CBX2_27304074_Chip-Seq_ESCs_Mouse1.17862911
69UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.17230535
70CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.17048509
71SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.15775815
72OCT4_19829295_ChIP-Seq_ESCs_Human1.15319943
73AR_25329375_ChIP-Seq_VCAP_Human1.15111789
74P300_19829295_ChIP-Seq_ESCs_Human1.14725898
75DNAJC2_21179169_ChIP-ChIP_NT2_Human1.13620121
76GATA1_26923725_Chip-Seq_HPCs_Mouse1.13513275
77PHF8_20622854_ChIP-Seq_HELA_Human1.12955908
78TOP2B_26459242_ChIP-Seq_MCF-7_Human1.12423142
79SA1_27219007_Chip-Seq_ERYTHROID_Human1.11950805
80MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.11391426
81WT1_25993318_ChIP-Seq_PODOCYTE_Human1.11020992
82RING1B_27294783_Chip-Seq_NPCs_Mouse1.10873681
83E2F1_20622854_ChIP-Seq_HELA_Human1.10301451
84EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.10123660
85SA1_27219007_Chip-Seq_Bcells_Human1.09957835
86RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09837643
87RNF2_27304074_Chip-Seq_NSC_Mouse1.09549558
88AR_19668381_ChIP-Seq_PC3_Human1.09029366
89KDM2B_26808549_Chip-Seq_K562_Human1.08768239
90TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07043291
91PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.06456304
92STAT3_23295773_ChIP-Seq_U87_Human1.06387403
93TP63_22573176_ChIP-Seq_HFKS_Human1.05934230
94VDR_22108803_ChIP-Seq_LS180_Human1.05851029
95SMAD3_21741376_ChIP-Seq_ESCs_Human1.05708862
96ELF1_20517297_ChIP-Seq_JURKAT_Human1.05532923
97TP53_23651856_ChIP-Seq_MEFs_Mouse1.04780037
98SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04182528
99CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.03716031
100ZFP281_27345836_Chip-Seq_ESCs_Mouse1.03663507
101IGF1R_20145208_ChIP-Seq_DFB_Human1.03359217
102ZFP281_18757296_ChIP-ChIP_E14_Mouse1.03215435
103OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03043534
104WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02723691
105BCL6_27268052_Chip-Seq_Bcells_Human1.02654371
106TET1_21490601_ChIP-Seq_MESCs_Mouse0.99797277
107GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98792682
108TCF4_23295773_ChIP-Seq_U87_Human0.98093875
109NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.98003739
110P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97722607
111CTCF_27219007_Chip-Seq_Bcells_Human0.97405147
112ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.96775727
113TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.96290230
114BMI1_23680149_ChIP-Seq_NPCS_Mouse0.96017862
115TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95561236
116YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95279886
117SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.95273674
118FOXP1_21924763_ChIP-Seq_HESCs_Human0.94468020
119RARA_24833708_ChIP-Seq_LIVER_Mouse0.94193353
120STAT6_21828071_ChIP-Seq_BEAS2B_Human0.93568483
121RARG_19884340_ChIP-ChIP_MEFs_Mouse0.93287302
122TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92913089
123PIAS1_25552417_ChIP-Seq_VCAP_Human0.92812681
124RAD21_21589869_ChIP-Seq_MESCs_Mouse0.91946623
125SOX3_22085726_ChIP-Seq_NPCs_Mouse0.91774687
126TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91764771
127POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91764771
128ZNF217_24962896_ChIP-Seq_MCF-7_Human0.91583936
129TP53_22127205_ChIP-Seq_IMR90_Human0.91222860
130RUNX1_27514584_Chip-Seq_MCF-7_Human0.90544071
131BCOR_27268052_Chip-Seq_Bcells_Human0.89619316
132YY1_22570637_ChIP-Seq_MALME-3M_Human0.89174140
133RUNX2_22187159_ChIP-Seq_PCA_Human0.88778291
134RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.88336903
135ARNT_22903824_ChIP-Seq_MCF-7_Human0.87577560
136GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86759903
137SMAD4_21741376_ChIP-Seq_HESCs_Human0.86746630
138KLF4_19829295_ChIP-Seq_ESCs_Human0.86698119
139PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.86631573
140AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.86027191
141SMC3_22415368_ChIP-Seq_MEFs_Mouse0.85847260
142OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.85784038
143BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.85438789
144STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.85075765
145RARB_24833708_ChIP-Seq_LIVER_Mouse0.83382856
146JUN_21703547_ChIP-Seq_K562_Human0.83348194
147NR3C1_21868756_ChIP-Seq_MCF10A_Human0.83275129
148FUS_26573619_Chip-Seq_HEK293_Human0.83173372
149FLI1_21867929_ChIP-Seq_TH2_Mouse0.83070687
150SMAD4_21741376_ChIP-Seq_EPCs_Human0.81965523

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.31550791
2MP0003880_abnormal_central_pattern4.34382385
3MP0003635_abnormal_synaptic_transmissio4.06781785
4MP0004270_analgesia3.98523713
5MP0002063_abnormal_learning/memory/cond3.33314334
6MP0009745_abnormal_behavioral_response3.16485082
7MP0002064_seizures2.92777214
8MP0002572_abnormal_emotion/affect_behav2.72482963
9MP0001968_abnormal_touch/_nociception2.70321412
10MP0003123_paternal_imprinting2.65972690
11MP0002734_abnormal_mechanical_nocicepti2.61494766
12MP0005423_abnormal_somatic_nervous2.58317998
13MP0009046_muscle_twitch2.52135132
14MP0009780_abnormal_chondrocyte_physiolo2.43069624
15MP0009379_abnormal_foot_pigmentation2.42064670
16MP0002272_abnormal_nervous_system2.38560798
17MP0001486_abnormal_startle_reflex2.36201772
18MP0005410_abnormal_fertilization2.25753290
19MP0003329_amyloid_beta_deposits2.23104158
20MP0008875_abnormal_xenobiotic_pharmacok2.16215202
21MP0002909_abnormal_adrenal_gland2.15038232
22MP0001440_abnormal_grooming_behavior2.13232789
23MP0002733_abnormal_thermal_nociception2.10030252
24MP0002822_catalepsy2.07926704
25MP0000778_abnormal_nervous_system2.06763599
26MP0001501_abnormal_sleep_pattern2.02892647
27MP0002736_abnormal_nociception_after1.98617967
28MP0002735_abnormal_chemical_nociception1.96762217
29MP0001970_abnormal_pain_threshold1.91149861
30MP0010030_abnormal_orbit_morphology1.90879845
31MP0004811_abnormal_neuron_physiology1.87236178
32MP0002184_abnormal_innervation1.85202081
33MP0008789_abnormal_olfactory_epithelium1.82687770
34MP0002557_abnormal_social/conspecific_i1.78968981
35MP0002160_abnormal_reproductive_system1.77056489
36MP0004858_abnormal_nervous_system1.76415473
37MP0003879_abnormal_hair_cell1.73147421
38MP0002067_abnormal_sensory_capabilities1.71496993
39MP0004133_heterotaxia1.68453148
40MP0000955_abnormal_spinal_cord1.65550206
41MP0004885_abnormal_endolymph1.63457954
42MP0004924_abnormal_behavior1.63332520
43MP0005386_behavior/neurological_phenoty1.63332520
44MP0008569_lethality_at_weaning1.61445233
45MP0001984_abnormal_olfaction1.58675802
46MP0006276_abnormal_autonomic_nervous1.57857035
47MP0002882_abnormal_neuron_morphology1.47871506
48MP0005645_abnormal_hypothalamus_physiol1.43674803
49MP0001986_abnormal_taste_sensitivity1.40831046
50MP0002066_abnormal_motor_capabilities/c1.40723500
51MP0005646_abnormal_pituitary_gland1.37514177
52MP0001529_abnormal_vocalization1.37325477
53MP0003787_abnormal_imprinting1.35629535
54MP0000013_abnormal_adipose_tissue1.33556824
55MP0003122_maternal_imprinting1.32961369
56MP0001346_abnormal_lacrimal_gland1.30621631
57MP0001502_abnormal_circadian_rhythm1.30429060
58MP0001905_abnormal_dopamine_level1.27819179
59MP0003633_abnormal_nervous_system1.23262815
60MP0002152_abnormal_brain_morphology1.19152021
61MP0002837_dystrophic_cardiac_calcinosis1.18484838
62MP0003283_abnormal_digestive_organ1.18446042
63MP0000566_synostosis1.14737767
64MP0003878_abnormal_ear_physiology1.13749886
65MP0005377_hearing/vestibular/ear_phenot1.13749886
66MP0004130_abnormal_muscle_cell1.05301586
67MP0000026_abnormal_inner_ear1.04510661
68MP0003631_nervous_system_phenotype1.03327366
69MP0010386_abnormal_urinary_bladder1.02876674
70MP0000604_amyloidosis1.02863819
71MP0005248_abnormal_Harderian_gland1.01680717
72MP0003942_abnormal_urinary_system1.01626902
73MP0003634_abnormal_glial_cell1.00329712
74MP0002229_neurodegeneration0.99093895
75MP0003698_abnormal_male_reproductive0.98976004
76MP0004233_abnormal_muscle_weight0.98903559
77MP0000631_abnormal_neuroendocrine_gland0.98417098
78MP0002234_abnormal_pharynx_morphology0.96784939
79MP0003121_genomic_imprinting0.96157253
80MP0002249_abnormal_larynx_morphology0.95509372
81MP0002069_abnormal_eating/drinking_beha0.94364815
82MP0008961_abnormal_basal_metabolism0.91012667
83MP0005394_taste/olfaction_phenotype0.90880136
84MP0005499_abnormal_olfactory_system0.90880136
85MP0004142_abnormal_muscle_tone0.90827860
86MP0003938_abnormal_ear_development0.89251994
87MP0000678_abnormal_parathyroid_gland0.86495584
88MP0005551_abnormal_eye_electrophysiolog0.86013074
89MP0004742_abnormal_vestibular_system0.85522336
90MP0004145_abnormal_muscle_electrophysio0.84344196
91MP0000569_abnormal_digit_pigmentation0.82168136
92MP0000049_abnormal_middle_ear0.81315072
93MP0005389_reproductive_system_phenotype0.81298470
94MP0005535_abnormal_body_temperature0.80911851
95MP0005623_abnormal_meninges_morphology0.80580085
96MP0001963_abnormal_hearing_physiology0.78765400
97MP0000920_abnormal_myelination0.78714200
98MP0000751_myopathy0.78140352
99MP0001765_abnormal_ion_homeostasis0.76788008
100MP0002752_abnormal_somatic_nervous0.76785277
101MP0001177_atelectasis0.75368104
102MP0002876_abnormal_thyroid_physiology0.75262109
103MP0001348_abnormal_lacrimal_gland0.73573015
104MP0003861_abnormal_nervous_system0.72284160
105MP0001188_hyperpigmentation0.71583020
106MP0006072_abnormal_retinal_apoptosis0.71325190
107MP0003075_altered_response_to0.71309560
108MP0004085_abnormal_heartbeat0.70281151
109MP0003632_abnormal_nervous_system0.70231718
110MP0002090_abnormal_vision0.68678694
111MP0006292_abnormal_olfactory_placode0.68510764
112MP0001485_abnormal_pinna_reflex0.67685376
113MP0004043_abnormal_pH_regulation0.66481831
114MP0008877_abnormal_DNA_methylation0.66228085
115MP0008874_decreased_physiological_sensi0.64955607
116MP0005195_abnormal_posterior_eye0.64788063
117MP0003172_abnormal_lysosome_physiology0.62830558
118MP0002928_abnormal_bile_duct0.61839514
119MP0001299_abnormal_eye_distance/0.61583436
120MP0000534_abnormal_ureter_morphology0.61482699
121MP0003690_abnormal_glial_cell0.61093725
122MP0001664_abnormal_digestion0.59660598
123MP0005187_abnormal_penis_morphology0.58359553
124MP0005409_darkened_coat_color0.56621346
125MP0008872_abnormal_physiological_respon0.55421731
126MP0002653_abnormal_ependyma_morphology0.54899541
127MP0002638_abnormal_pupillary_reflex0.54366926

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.96116923
2Myokymia (HP:0002411)5.70314973
3Visual hallucinations (HP:0002367)5.31147878
4Focal seizures (HP:0007359)4.81931146
5Chronic bronchitis (HP:0004469)4.64653727
6Epileptic encephalopathy (HP:0200134)4.27408027
7Nasal polyposis (HP:0100582)4.22872322
8Supranuclear gaze palsy (HP:0000605)4.17737569
9Bronchiectasis (HP:0002110)4.16975558
10Atonic seizures (HP:0010819)3.97158114
11Cerebral inclusion bodies (HP:0100314)3.78911647
12Neurofibrillary tangles (HP:0002185)3.76132021
13Absence seizures (HP:0002121)3.52098671
14Progressive cerebellar ataxia (HP:0002073)3.49508702
15Absent/shortened dynein arms (HP:0200106)3.39952776
16Dynein arm defect of respiratory motile cilia (HP:0012255)3.39952776
17Abnormality of the nasal mucosa (HP:0000433)3.34030031
18Ankle clonus (HP:0011448)3.20138079
19Dialeptic seizures (HP:0011146)3.20082457
20Mutism (HP:0002300)3.17948280
21Papilledema (HP:0001085)3.16277496
22Generalized tonic-clonic seizures (HP:0002069)3.13083552
23Depression (HP:0000716)3.10867980
24Poor eye contact (HP:0000817)3.04280417
25Hyperventilation (HP:0002883)3.01063388
26Febrile seizures (HP:0002373)3.00479823
27Epileptiform EEG discharges (HP:0011182)2.97782817
28Atelectasis (HP:0100750)2.95867317
29EEG with generalized epileptiform discharges (HP:0011198)2.94920880
30Impaired vibration sensation in the lower limbs (HP:0002166)2.92853530
31Amyotrophic lateral sclerosis (HP:0007354)2.91361662
32Broad-based gait (HP:0002136)2.88613164
33Hypsarrhythmia (HP:0002521)2.86936723
34Molar tooth sign on MRI (HP:0002419)2.83202527
35Abnormality of midbrain morphology (HP:0002418)2.83202527
36Action tremor (HP:0002345)2.79962547
37Anxiety (HP:0000739)2.77528269
38Amblyopia (HP:0000646)2.76635732
39Male infertility (HP:0003251)2.76057550
40Urinary bladder sphincter dysfunction (HP:0002839)2.74861556
41True hermaphroditism (HP:0010459)2.74137660
42Abnormal social behavior (HP:0012433)2.72775628
43Impaired social interactions (HP:0000735)2.72775628
44Pancreatic fibrosis (HP:0100732)2.68506087
45Abnormality of the corticospinal tract (HP:0002492)2.67206593
46Annular pancreas (HP:0001734)2.66682358
47Limb dystonia (HP:0002451)2.64454971
48Drooling (HP:0002307)2.63923705
49Excessive salivation (HP:0003781)2.63923705
50Hemiparesis (HP:0001269)2.63578777
51Spastic gait (HP:0002064)2.61920472
52Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.60140614
53Truncal ataxia (HP:0002078)2.59030067
54Abnormal eating behavior (HP:0100738)2.58785176
55Abnormality of the lower motor neuron (HP:0002366)2.57202791
56Dysmetria (HP:0001310)2.57086368
57Megalencephaly (HP:0001355)2.56543986
58Nephronophthisis (HP:0000090)2.55297053
59Urinary urgency (HP:0000012)2.52736541
60Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.51247677
61Gaze-evoked nystagmus (HP:0000640)2.50598150
62Abnormal respiratory motile cilium physiology (HP:0012261)2.48380438
63Termporal pattern (HP:0011008)2.44283326
64Insidious onset (HP:0003587)2.44283326
65Dysdiadochokinesis (HP:0002075)2.43867415
66Torticollis (HP:0000473)2.43320876
67Agitation (HP:0000713)2.39753796
68Polyphagia (HP:0002591)2.38296379
69Postural instability (HP:0002172)2.37299267
70Occipital encephalocele (HP:0002085)2.37261276
71Absent speech (HP:0001344)2.34066871
72Impaired smooth pursuit (HP:0007772)2.32842222
73Akinesia (HP:0002304)2.30136442
74Rib fusion (HP:0000902)2.29771964
75Congenital primary aphakia (HP:0007707)2.28056428
76Cystic liver disease (HP:0006706)2.27566543
77Abnormal respiratory motile cilium morphology (HP:0005938)2.25328804
78Abnormal respiratory epithelium morphology (HP:0012253)2.25328804
79Diplopia (HP:0000651)2.23467460
80Abnormality of binocular vision (HP:0011514)2.23467460
81Genetic anticipation (HP:0003743)2.22647518
82Focal dystonia (HP:0004373)2.21084166
83Progressive inability to walk (HP:0002505)2.20678729
84Hand muscle atrophy (HP:0009130)2.19423533
85Medial flaring of the eyebrow (HP:0010747)2.18458470
86Bradykinesia (HP:0002067)2.18367300
87Retinal dysplasia (HP:0007973)2.17518027
88Abnormal ciliary motility (HP:0012262)2.15846750
89Stereotypic behavior (HP:0000733)2.14601351
90Gait imbalance (HP:0002141)2.14158539
91Lower limb muscle weakness (HP:0007340)2.12806128
92Delusions (HP:0000746)2.09971841
93Type II lissencephaly (HP:0007260)2.07424988
94Nephrogenic diabetes insipidus (HP:0009806)2.06699555
95Infertility (HP:0000789)2.05261804
96Intention tremor (HP:0002080)2.05139375
97Aplasia/Hypoplasia of the spleen (HP:0010451)2.04699499
98Asplenia (HP:0001746)2.03932288
99Hypoplasia of the brainstem (HP:0002365)2.03653312
100Aplasia/Hypoplasia of the brainstem (HP:0007362)2.03653312
101Pheochromocytoma (HP:0002666)2.03390533
102Abnormality of ocular smooth pursuit (HP:0000617)2.03328522
103Apathy (HP:0000741)2.01051910
104Neuronal loss in central nervous system (HP:0002529)2.00906017
105Rhinitis (HP:0012384)1.99570579
106Fetal akinesia sequence (HP:0001989)1.99069631
107Postaxial foot polydactyly (HP:0001830)1.98881779
108Craniofacial dystonia (HP:0012179)1.98785300
109Obstructive sleep apnea (HP:0002870)1.98019296
110Generalized myoclonic seizures (HP:0002123)1.96590840
111Recurrent otitis media (HP:0000403)1.95552129
112Inability to walk (HP:0002540)1.95067551
113Reticulocytopenia (HP:0001896)1.94541238
114Chronic sinusitis (HP:0011109)1.94399881
115Recurrent sinusitis (HP:0011108)1.93399232
116Pancreatic cysts (HP:0001737)1.90713170
117Insomnia (HP:0100785)1.89694372
118Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.89583959
119Degeneration of the lateral corticospinal tracts (HP:0002314)1.89583959
120Impaired vibratory sensation (HP:0002495)1.88501588
121Inappropriate behavior (HP:0000719)1.87667077
122Hyperthyroidism (HP:0000836)1.87184387
123Anencephaly (HP:0002323)1.83953695
124Decreased central vision (HP:0007663)1.83096027
125Rapidly progressive (HP:0003678)1.81647961
126Clonus (HP:0002169)1.81121117
127Lissencephaly (HP:0001339)1.80504258
128Abnormality of the renal medulla (HP:0100957)1.80474717
129Chronic hepatic failure (HP:0100626)1.80464550
130Renal dysplasia (HP:0000110)1.79843129
131Hepatoblastoma (HP:0002884)1.78832766
132Decreased circulating renin level (HP:0003351)1.77814754
133Intellectual disability, profound (HP:0002187)1.76740301
134Scanning speech (HP:0002168)1.76679096
135Sleep apnea (HP:0010535)1.75664792
136Upper limb amyotrophy (HP:0009129)1.72454366
137Distal upper limb amyotrophy (HP:0007149)1.72454366
138Vaginal atresia (HP:0000148)1.71650758
139Testicular atrophy (HP:0000029)1.71255334
140Turricephaly (HP:0000262)1.70633841
141Renal salt wasting (HP:0000127)1.68174817
142Bronchitis (HP:0012387)1.67916826
143Genital tract atresia (HP:0001827)1.66846413
144Diminished movement (HP:0002374)1.66723142
145Poor coordination (HP:0002370)1.64649827
146Aplasia/Hypoplasia of the tongue (HP:0010295)1.64473390
147Anomalous pulmonary venous return (HP:0010772)1.58305197
148Status epilepticus (HP:0002133)1.54065153
149Specific learning disability (HP:0001328)1.52001044
150Postaxial hand polydactyly (HP:0001162)1.51049949
151Abnormality of the aortic arch (HP:0012303)1.50045816
152Sclerocornea (HP:0000647)1.48046688
153Aplasia/Hypoplasia of the sacrum (HP:0008517)1.46969666
154Anosmia (HP:0000458)1.46464873
155Tubular atrophy (HP:0000092)1.44541232
156Hyperactive renin-angiotensin system (HP:0000841)1.42295556

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.24301375
2MAP3K94.14738243
3EPHA43.90105258
4NTRK33.74674579
5PRKD33.05181866
6MINK12.67116202
7MAP3K42.55909058
8PAK62.31635216
9DAPK22.24635154
10KSR22.12480127
11MAP2K72.02564482
12EPHA21.98794106
13NTRK11.97607808
14PNCK1.95026834
15NTRK21.89663397
16ARAF1.76026619
17CAMKK11.75029116
18KSR11.64713625
19RIPK41.59803815
20CDK51.53674748
21LATS21.47978414
22MAP3K121.47234607
23PLK21.44919152
24MAP2K41.44356250
25TYRO31.41645041
26UHMK11.40114047
27DAPK11.37835038
28MAPK131.36886197
29MAPKAPK31.35178314
30GRK51.34188892
31SIK21.32896390
32TRIB31.30190289
33MAP3K21.29155465
34TESK11.27572801
35TNIK1.25107027
36ICK1.23965384
37PRKCG1.21190630
38CASK1.21049761
39STK381.20747081
40PHKG11.14951396
41PHKG21.14951396
42PDK41.12060405
43PDK31.12060405
44MAP3K111.11979408
45STK161.08830639
46PTK2B1.07070626
47DYRK1B1.00779972
48CDK141.00747179
49CDK190.99208762
50CAMKK20.98159254
51CDK180.97496882
52CDK150.97052422
53MAP3K130.97024237
54PAK30.95241188
55CAMK2A0.94690139
56PRPF4B0.93634240
57CSNK1G20.90208874
58PIM20.88937011
59MUSK0.88703395
60FES0.88323761
61WNK40.87589810
62RAF10.84990246
63CDK11A0.84612203
64EEF2K0.84448685
65MARK20.84185206
66TAOK10.83746721
67PRKCI0.83291441
68DMPK0.80157513
69NEK60.79662717
70DYRK1A0.79571495
71LIMK10.78912492
72EPHB20.78483010
73DYRK20.77377292
74STK110.76060228
75PRKCH0.74134687
76CAMK2B0.72526575
77SIK10.71548069
78RET0.70104912
79CAMK10.68390979
80LRRK20.67492314
81PRKD20.66542066
82SCYL20.65903369
83PDK10.65342196
84MAPK150.64967026
85AURKA0.64351432
86ALK0.64105541
87IRAK20.63793693
88RIPK10.63362610
89MAP3K10.62255674
90PDPK10.62233994
91PRKCZ0.61163378
92MAPKAPK50.59085071
93STK390.58209617
94BMPR20.58067221
95BCR0.57576607
96CAMK1D0.55866319
97STK240.54819276
98OXSR10.52568517
99WNK30.51788620
100SGK4940.51203502
101SGK2230.51203502
102SGK10.50740294
103PINK10.50431907
104PRKCE0.49325212
105BRAF0.48777025
106MAP2K20.47106242
107ERBB20.46331218
108ILK0.45500517
109CAMK2D0.43338624
110FGR0.43304270
111NME10.42593808
112PKN10.41666437
113RPS6KA20.40734869
114PTK20.40032028
115PDK20.39669994
116FYN0.39329530
117CAMK1G0.38815651
118PRKACA0.38697050
119MAPK100.38033753
120RPS6KA30.37950507
121CSNK1G30.36842836
122FGFR20.36450039
123CCNB10.35304783
124WNK10.34113988
125CAMK2G0.33714859
126MAP3K60.33261029
127DAPK30.32951734
128MAP2K10.32406278

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.20680751
2Nicotine addiction_Homo sapiens_hsa050333.13874235
3Long-term potentiation_Homo sapiens_hsa047202.73867223
4Circadian entrainment_Homo sapiens_hsa047132.60134062
5Amphetamine addiction_Homo sapiens_hsa050312.57660559
6GABAergic synapse_Homo sapiens_hsa047272.51164946
7Olfactory transduction_Homo sapiens_hsa047402.44658465
8Glutamatergic synapse_Homo sapiens_hsa047242.43166852
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.42686546
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.36261955
11Morphine addiction_Homo sapiens_hsa050322.30057270
12Dopaminergic synapse_Homo sapiens_hsa047282.23404972
13Insulin secretion_Homo sapiens_hsa049112.22641126
14Salivary secretion_Homo sapiens_hsa049701.96907761
15Cholinergic synapse_Homo sapiens_hsa047251.93771525
16Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.83935383
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.82301937
18Cocaine addiction_Homo sapiens_hsa050301.78597743
19Gastric acid secretion_Homo sapiens_hsa049711.76970638
20Renin secretion_Homo sapiens_hsa049241.73171214
21Phenylalanine metabolism_Homo sapiens_hsa003601.71349211
22Taste transduction_Homo sapiens_hsa047421.67389096
23Serotonergic synapse_Homo sapiens_hsa047261.64031681
24Collecting duct acid secretion_Homo sapiens_hsa049661.62141158
25Long-term depression_Homo sapiens_hsa047301.61392144
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.59606669
27Oxytocin signaling pathway_Homo sapiens_hsa049211.58491216
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.52540209
29Sulfur relay system_Homo sapiens_hsa041221.43845274
30Gap junction_Homo sapiens_hsa045401.41477776
31GnRH signaling pathway_Homo sapiens_hsa049121.38540595
32Estrogen signaling pathway_Homo sapiens_hsa049151.37640874
33Calcium signaling pathway_Homo sapiens_hsa040201.35883246
34Axon guidance_Homo sapiens_hsa043601.34626846
35Glycosaminoglycan degradation_Homo sapiens_hsa005311.32193493
36Vibrio cholerae infection_Homo sapiens_hsa051101.31392961
37Type II diabetes mellitus_Homo sapiens_hsa049301.27469568
38Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.23333506
39Huntingtons disease_Homo sapiens_hsa050161.22633144
40cAMP signaling pathway_Homo sapiens_hsa040241.21969907
41Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.20563269
42Tyrosine metabolism_Homo sapiens_hsa003501.18718153
43Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.17829191
44Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17616311
45Glioma_Homo sapiens_hsa052141.15959633
46Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.15002460
47Melanogenesis_Homo sapiens_hsa049161.11501763
48Histidine metabolism_Homo sapiens_hsa003401.09955489
49Phosphatidylinositol signaling system_Homo sapiens_hsa040701.03924113
50cGMP-PKG signaling pathway_Homo sapiens_hsa040221.02677409
51Oocyte meiosis_Homo sapiens_hsa041141.01545530
52ErbB signaling pathway_Homo sapiens_hsa040121.00938589
53Cardiac muscle contraction_Homo sapiens_hsa042600.98895710
54Dorso-ventral axis formation_Homo sapiens_hsa043200.98119463
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.96265881
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93399935
57Hippo signaling pathway_Homo sapiens_hsa043900.92819366
58Sphingolipid metabolism_Homo sapiens_hsa006000.91664576
59beta-Alanine metabolism_Homo sapiens_hsa004100.91456874
60Phototransduction_Homo sapiens_hsa047440.90239669
61Basal cell carcinoma_Homo sapiens_hsa052170.89900505
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.89601304
63Glucagon signaling pathway_Homo sapiens_hsa049220.87641468
64Pancreatic secretion_Homo sapiens_hsa049720.87561950
65Thyroid hormone synthesis_Homo sapiens_hsa049180.85139162
66Chemical carcinogenesis_Homo sapiens_hsa052040.85138307
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.81146401
68Phospholipase D signaling pathway_Homo sapiens_hsa040720.80827922
69VEGF signaling pathway_Homo sapiens_hsa043700.80711812
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.78888486
71Parkinsons disease_Homo sapiens_hsa050120.77850269
72Type I diabetes mellitus_Homo sapiens_hsa049400.76612272
73Notch signaling pathway_Homo sapiens_hsa043300.74022700
74Choline metabolism in cancer_Homo sapiens_hsa052310.73522610
75Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.71344484
76MAPK signaling pathway_Homo sapiens_hsa040100.70440887
77Arginine and proline metabolism_Homo sapiens_hsa003300.69146825
78Alcoholism_Homo sapiens_hsa050340.69065982
79Tight junction_Homo sapiens_hsa045300.68221801
80Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68200579
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.67868516
82Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.66843589
83Ras signaling pathway_Homo sapiens_hsa040140.66049548
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64641590
85Ribosome_Homo sapiens_hsa030100.64515546
86Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64424246
87Prion diseases_Homo sapiens_hsa050200.64267646
88Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.63427980
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63153921
90Renal cell carcinoma_Homo sapiens_hsa052110.60870252
91Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59677763
92Endocytosis_Homo sapiens_hsa041440.58962717
93Folate biosynthesis_Homo sapiens_hsa007900.58046098
94Dilated cardiomyopathy_Homo sapiens_hsa054140.56465612
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.56429245
96mTOR signaling pathway_Homo sapiens_hsa041500.55539389
97Alzheimers disease_Homo sapiens_hsa050100.55442104
98Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55211770
99Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53186080
100Wnt signaling pathway_Homo sapiens_hsa043100.52483358
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52243916
102Endometrial cancer_Homo sapiens_hsa052130.51001860
103Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49803800
104Linoleic acid metabolism_Homo sapiens_hsa005910.49157147
105Rap1 signaling pathway_Homo sapiens_hsa040150.48594959
106Insulin signaling pathway_Homo sapiens_hsa049100.47165580
107Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46714349
108Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.45032173
109Fatty acid biosynthesis_Homo sapiens_hsa000610.43737476
110AMPK signaling pathway_Homo sapiens_hsa041520.42811130
111Inositol phosphate metabolism_Homo sapiens_hsa005620.42769448
112Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41005793
113Circadian rhythm_Homo sapiens_hsa047100.39936160
114Non-small cell lung cancer_Homo sapiens_hsa052230.39794213
115Hedgehog signaling pathway_Homo sapiens_hsa043400.34872590
116Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.32626828
117Colorectal cancer_Homo sapiens_hsa052100.30806130
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.29987314
119Maturity onset diabetes of the young_Homo sapiens_hsa049500.29492334
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.29187386
121Bile secretion_Homo sapiens_hsa049760.28205827
122Ovarian steroidogenesis_Homo sapiens_hsa049130.28128022
123Glycerophospholipid metabolism_Homo sapiens_hsa005640.28008556
124Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.27884562
125Oxidative phosphorylation_Homo sapiens_hsa001900.27843791
126SNARE interactions in vesicular transport_Homo sapiens_hsa041300.26018208
127Central carbon metabolism in cancer_Homo sapiens_hsa052300.25831012
128Prolactin signaling pathway_Homo sapiens_hsa049170.25417169

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