LRRC74B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium movement (GO:0003341)6.22928954
2axonemal dynein complex assembly (GO:0070286)5.98716392
3GTP biosynthetic process (GO:0006183)5.74442340
4cilium or flagellum-dependent cell motility (GO:0001539)5.43350757
5axoneme assembly (GO:0035082)5.24385646
6behavioral response to nicotine (GO:0035095)4.98116971
7UTP biosynthetic process (GO:0006228)4.73306813
8regulation of cilium movement (GO:0003352)4.69986129
9left/right axis specification (GO:0070986)4.55637466
10superoxide anion generation (GO:0042554)4.41657160
11nucleoside diphosphate phosphorylation (GO:0006165)4.30853622
12guanosine-containing compound biosynthetic process (GO:1901070)4.07811486
13epithelial cilium movement (GO:0003351)4.06565338
14UTP metabolic process (GO:0046051)3.93921970
15L-fucose catabolic process (GO:0042355)3.83381389
16fucose catabolic process (GO:0019317)3.83381389
17L-fucose metabolic process (GO:0042354)3.83381389
18CTP metabolic process (GO:0046036)3.79400266
19CTP biosynthetic process (GO:0006241)3.79400266
20DNA deamination (GO:0045006)3.75427737
21indolalkylamine metabolic process (GO:0006586)3.69681343
22cilium morphogenesis (GO:0060271)3.64117091
23protein localization to cilium (GO:0061512)3.62555312
24tryptophan catabolic process (GO:0006569)3.47106104
25indole-containing compound catabolic process (GO:0042436)3.47106104
26indolalkylamine catabolic process (GO:0046218)3.47106104
27mesenchymal cell differentiation involved in kidney development (GO:0072161)3.47032240
28mesenchymal cell differentiation involved in renal system development (GO:2001012)3.47032240
29pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.43898508
30daunorubicin metabolic process (GO:0044597)3.42786597
31polyketide metabolic process (GO:0030638)3.42786597
32doxorubicin metabolic process (GO:0044598)3.42786597
33tryptophan metabolic process (GO:0006568)3.39686705
34sulfation (GO:0051923)3.33990975
35epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.33782385
36motile cilium assembly (GO:0044458)3.33711713
37centriole assembly (GO:0098534)3.30137459
38regulation of microtubule-based movement (GO:0060632)3.27947956
39intraciliary transport (GO:0042073)3.22893825
40left/right pattern formation (GO:0060972)3.22815035
41kynurenine metabolic process (GO:0070189)3.19323269
42pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.18237018
43protein polyglutamylation (GO:0018095)3.18044084
44cellular ketone body metabolic process (GO:0046950)3.17764426
45cilium organization (GO:0044782)3.17228398
46cilium assembly (GO:0042384)3.15427970
47detection of light stimulus involved in visual perception (GO:0050908)3.14514859
48detection of light stimulus involved in sensory perception (GO:0050962)3.14514859
49adaptation of signaling pathway (GO:0023058)3.12023609
50microtubule bundle formation (GO:0001578)3.10540834
51tachykinin receptor signaling pathway (GO:0007217)3.08658910
52deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.08519366
53regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.08448988
54ganglion development (GO:0061548)3.07610739
55exogenous drug catabolic process (GO:0042738)3.05359431
56deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.99947907
57mitochondrial respiratory chain complex I assembly (GO:0032981)2.99633543
58NADH dehydrogenase complex assembly (GO:0010257)2.99633543
59mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.99633543
60retinal cone cell development (GO:0046549)2.99028831
61photoreceptor cell maintenance (GO:0045494)2.97499675
62energy homeostasis (GO:0097009)2.97426750
63regulation of germinal center formation (GO:0002634)2.96941354
64response to pheromone (GO:0019236)2.96488249
65regulation of collateral sprouting (GO:0048670)2.95443017
66rRNA catabolic process (GO:0016075)2.90846707
67positive regulation of cellular amide metabolic process (GO:0034250)2.90717320
68nucleotide phosphorylation (GO:0046939)2.90445534
69pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.89488549
70ketone body metabolic process (GO:1902224)2.88763686
71water-soluble vitamin biosynthetic process (GO:0042364)2.87593227
72DNA strand renaturation (GO:0000733)2.87141665
73drug catabolic process (GO:0042737)2.86721671
74cornea development in camera-type eye (GO:0061303)2.86466587
75RNA-dependent DNA replication (GO:0006278)2.86409663
76detection of molecule of bacterial origin (GO:0032490)2.85794823
77protein complex biogenesis (GO:0070271)2.85072819
78positive regulation of oligodendrocyte differentiation (GO:0048714)2.84613686
79response to xenobiotic stimulus (GO:0009410)2.83885048
80piRNA metabolic process (GO:0034587)2.83828502
81dendritic cell chemotaxis (GO:0002407)2.82358629
82positive regulation of protein homodimerization activity (GO:0090073)2.80321792
83sperm motility (GO:0030317)2.80251608
84nonmotile primary cilium assembly (GO:0035058)2.78832635
85natural killer cell activation involved in immune response (GO:0002323)2.77666604
86regulation of timing of cell differentiation (GO:0048505)2.76489163
87nucleoside diphosphate metabolic process (GO:0009132)2.75365669
88negative regulation of mast cell activation (GO:0033004)2.75309495
89indole-containing compound metabolic process (GO:0042430)2.74834502
90negative regulation of T cell differentiation in thymus (GO:0033085)2.73099443
91regulation of action potential (GO:0098900)2.72175299
92replicative senescence (GO:0090399)2.72063775
93regulation of nuclear cell cycle DNA replication (GO:0033262)2.71571800
94deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.71187091
95neural tube formation (GO:0001841)2.69561007
96keratinocyte development (GO:0003334)2.69159483
97pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.68390248
98platelet dense granule organization (GO:0060155)2.67441606
99tRNA methylation (GO:0030488)2.67404116
100negative regulation of keratinocyte proliferation (GO:0010839)2.67144153
101regulation of development, heterochronic (GO:0040034)2.63827007
102superoxide metabolic process (GO:0006801)2.62928602
103determination of left/right symmetry (GO:0007368)2.62465498
104neuronal action potential (GO:0019228)2.62149523
105detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.61638926
106gamma-aminobutyric acid transport (GO:0015812)2.60984883
107positive regulation of protein sumoylation (GO:0033235)2.60146569
108detection of other organism (GO:0098543)2.57534679
109smoothened signaling pathway (GO:0007224)2.57430807
110cell projection assembly (GO:0030031)2.57313474
111behavioral response to ethanol (GO:0048149)2.57218774
112protein-cofactor linkage (GO:0018065)2.57068699
113negative regulation of myoblast differentiation (GO:0045662)2.56419522
114mitochondrial respiratory chain complex assembly (GO:0033108)2.56126455
115spinal cord motor neuron differentiation (GO:0021522)2.56043042
116adenosine metabolic process (GO:0046085)2.54089416
117ventricular system development (GO:0021591)2.54044643
118preassembly of GPI anchor in ER membrane (GO:0016254)2.53499876
119positive regulation of uterine smooth muscle contraction (GO:0070474)2.52792687
120multicellular organism reproduction (GO:0032504)2.52396844
121response to peptidoglycan (GO:0032494)2.50707906
122reflex (GO:0060004)2.50295197
123nucleotide transmembrane transport (GO:1901679)2.49263408
124benzene-containing compound metabolic process (GO:0042537)2.48834128
125negative regulation of cytosolic calcium ion concentration (GO:0051481)2.48751348
126cellular biogenic amine catabolic process (GO:0042402)2.48374687
127amine catabolic process (GO:0009310)2.48374687
128glycosphingolipid catabolic process (GO:0046479)2.48145052
129purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.47687912
130extracellular regulation of signal transduction (GO:1900115)2.47589732
131extracellular negative regulation of signal transduction (GO:1900116)2.47589732
132facial nerve structural organization (GO:0021612)2.47262217
133regulation of RIG-I signaling pathway (GO:0039535)2.45915580
134photoreceptor cell development (GO:0042461)2.45196664
135determination of bilateral symmetry (GO:0009855)2.43870838
136DNA integration (GO:0015074)2.43637648
137oligosaccharide catabolic process (GO:0009313)2.43595397
138DNA methylation involved in gamete generation (GO:0043046)2.43217839
139telomere maintenance via telomerase (GO:0007004)2.42736534
140NAD biosynthetic process (GO:0009435)2.41019298
141negative regulation of DNA-dependent DNA replication (GO:2000104)2.40129533
142embryonic camera-type eye development (GO:0031076)2.39879877
143negative regulation of systemic arterial blood pressure (GO:0003085)2.39868041
144startle response (GO:0001964)2.39578321
145regulation of hippo signaling (GO:0035330)2.39516781
146thyroid hormone metabolic process (GO:0042403)2.39225702
147respiratory chain complex IV assembly (GO:0008535)2.38666776
148adenine nucleotide transport (GO:0051503)2.38248498
149ceramide catabolic process (GO:0046514)2.38145385
150detection of external biotic stimulus (GO:0098581)2.37102048
151proteasome assembly (GO:0043248)2.36876337
1523-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.35846721
153purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.35846721
154primary alcohol catabolic process (GO:0034310)2.35837977
155one-carbon compound transport (GO:0019755)2.35699635
156specification of symmetry (GO:0009799)2.35491970
157cellular component assembly involved in morphogenesis (GO:0010927)2.34598401
158regulation of interleukin-8 secretion (GO:2000482)2.33995390
159synaptic transmission, cholinergic (GO:0007271)2.33268370
160negative regulation of transcription regulatory region DNA binding (GO:2000678)2.32620509
161regulation of rhodopsin mediated signaling pathway (GO:0022400)2.30387584
162positive regulation of heat generation (GO:0031652)2.27849709
163dendritic cell migration (GO:0036336)2.27609986
164DNA-dependent DNA replication (GO:0006261)2.25539899
165lateral ventricle development (GO:0021670)2.24859574
166multicellular organismal aging (GO:0010259)2.24720340
167pyrimidine nucleotide biosynthetic process (GO:0006221)2.22723753
168negative regulation of telomere maintenance (GO:0032205)2.22498443
169pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.22220509
170pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.21664189
171response to UV-B (GO:0010224)2.21113426
172pyrimidine dimer repair (GO:0006290)2.20753237
173cell differentiation involved in metanephros development (GO:0072202)2.20134739
174centriole replication (GO:0007099)2.19865410
175DNA catabolic process, exonucleolytic (GO:0000738)2.19523807
176regulation of non-canonical Wnt signaling pathway (GO:2000050)2.19202916
177glycolipid catabolic process (GO:0019377)2.18574642
178germinal center formation (GO:0002467)2.18493850
179negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)2.18424196
180neutrophil activation (GO:0042119)2.18406852
181cytochrome complex assembly (GO:0017004)2.18370928

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.55400668
2GBX2_23144817_ChIP-Seq_PC3_Human3.33841183
3PCGF2_27294783_Chip-Seq_ESCs_Mouse3.09924045
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.97473628
5FLI1_27457419_Chip-Seq_LIVER_Mouse2.90207089
6SUZ12_27294783_Chip-Seq_NPCs_Mouse2.66828054
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.64902618
8GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.56664187
9NFE2_27457419_Chip-Seq_LIVER_Mouse2.50382461
10PCGF2_27294783_Chip-Seq_NPCs_Mouse2.41936372
11TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.40845994
12BMI1_23680149_ChIP-Seq_NPCS_Mouse2.31203884
13SMAD_19615063_ChIP-ChIP_OVARY_Human2.12152177
14STAT3_18555785_Chip-Seq_ESCs_Mouse2.11254136
15E2F1_18555785_Chip-Seq_ESCs_Mouse2.02808968
16SUZ12_18555785_Chip-Seq_ESCs_Mouse2.02606208
17EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse2.02028859
18P53_22387025_ChIP-Seq_ESCs_Mouse2.00721102
19EZH2_27294783_Chip-Seq_NPCs_Mouse1.96522211
20EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.96207822
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.95930304
22TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.94955022
23POU3F2_20337985_ChIP-ChIP_501MEL_Human1.94509958
24NMYC_18555785_Chip-Seq_ESCs_Mouse1.92517277
25NANOG_18555785_Chip-Seq_ESCs_Mouse1.89433459
26ZFX_18555785_Chip-Seq_ESCs_Mouse1.87088503
27IGF1R_20145208_ChIP-Seq_DFB_Human1.84525100
28P300_18555785_Chip-Seq_ESCs_Mouse1.84177465
29RNF2_27304074_Chip-Seq_NSC_Mouse1.82805770
30CMYC_18555785_Chip-Seq_ESCs_Mouse1.82288869
31RUNX1_27457419_Chip-Seq_LIVER_Mouse1.81925140
32SOX2_18555785_Chip-Seq_ESCs_Mouse1.79763223
33OCT4_18555785_Chip-Seq_ESCs_Mouse1.79664707
34BCAT_22108803_ChIP-Seq_LS180_Human1.77982290
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.76625729
36PU1_27457419_Chip-Seq_LIVER_Mouse1.76427304
37CBX2_27304074_Chip-Seq_ESCs_Mouse1.76275462
38AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.72395446
39KLF4_18555785_Chip-Seq_ESCs_Mouse1.72276626
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.69632234
41ESRRB_18555785_Chip-Seq_ESCs_Mouse1.69588767
42SMAD1_18555785_Chip-Seq_ESCs_Mouse1.63587168
43MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.62728849
44TP63_19390658_ChIP-ChIP_HaCaT_Human1.62452973
45ER_23166858_ChIP-Seq_MCF-7_Human1.60178002
46P300_19829295_ChIP-Seq_ESCs_Human1.60077474
47FUS_26573619_Chip-Seq_HEK293_Human1.57692104
48CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57643575
49SALL1_21062744_ChIP-ChIP_HESCs_Human1.57505358
50RBPJ_22232070_ChIP-Seq_NCS_Mouse1.56617863
51CTCF_18555785_Chip-Seq_ESCs_Mouse1.55766171
52EED_16625203_ChIP-ChIP_MESCs_Mouse1.54312978
53NR3C1_21868756_ChIP-Seq_MCF10A_Human1.53928175
54CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.52448105
55CBP_20019798_ChIP-Seq_JUKART_Human1.50004971
56IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.50004971
57TCF4_23295773_ChIP-Seq_U87_Human1.48789943
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.48708514
59UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.48157732
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.45353592
61EWS_26573619_Chip-Seq_HEK293_Human1.45315976
62IRF8_21731497_ChIP-ChIP_J774_Mouse1.45263334
63HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.43170715
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.42593472
65AR_25329375_ChIP-Seq_VCAP_Human1.39841952
66LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.38713820
67CRX_20693478_ChIP-Seq_RETINA_Mouse1.38553849
68SMAD3_21741376_ChIP-Seq_EPCs_Human1.37412104
69KAP1_22055183_ChIP-Seq_ESCs_Mouse1.34910445
70FOXA1_25329375_ChIP-Seq_VCAP_Human1.34812063
71FOXA1_27270436_Chip-Seq_PROSTATE_Human1.34812063
72TCF4_22108803_ChIP-Seq_LS180_Human1.34408982
73TAL1_26923725_Chip-Seq_HPCs_Mouse1.34239830
74DROSHA_22980978_ChIP-Seq_HELA_Human1.34153974
75REST_21632747_ChIP-Seq_MESCs_Mouse1.33772222
76OCT4_21477851_ChIP-Seq_ESCs_Mouse1.32850396
77KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.32684676
78HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.32383792
79VDR_22108803_ChIP-Seq_LS180_Human1.31610778
80MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.31418467
81GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.30851504
82PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.29361995
83NANOG_19829295_ChIP-Seq_ESCs_Human1.28389202
84SOX2_19829295_ChIP-Seq_ESCs_Human1.28389202
85PRDM14_20953172_ChIP-Seq_ESCs_Human1.26768579
86TP53_22573176_ChIP-Seq_HFKS_Human1.26456186
87SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.25847428
88RUNX2_22187159_ChIP-Seq_PCA_Human1.25689064
89SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.25406061
90CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.24737074
91SMAD4_21741376_ChIP-Seq_EPCs_Human1.24670562
92IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.23046465
93KLF5_20875108_ChIP-Seq_MESCs_Mouse1.22809946
94CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.21474279
95IRF1_19129219_ChIP-ChIP_H3396_Human1.21103602
96AR_21572438_ChIP-Seq_LNCaP_Human1.20565717
97SRF_21415370_ChIP-Seq_HL-1_Mouse1.20302381
98TAF15_26573619_Chip-Seq_HEK293_Human1.18759180
99EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.18439612
100IRF8_22096565_ChIP-ChIP_GC-B_Human1.17625734
101NCOR_22424771_ChIP-Seq_293T_Human1.17524188
102EZH2_22144423_ChIP-Seq_EOC_Human1.17441695
103TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16905957
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.16631849
105GATA3_21878914_ChIP-Seq_MCF-7_Human1.16588596
106BP1_19119308_ChIP-ChIP_Hs578T_Human1.15820312
107PIAS1_25552417_ChIP-Seq_VCAP_Human1.14978906
108SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.14168754
109FOXA1_21572438_ChIP-Seq_LNCaP_Human1.13948434
110SMAD4_21799915_ChIP-Seq_A2780_Human1.13896758
111AR_20517297_ChIP-Seq_VCAP_Human1.13704618
112SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12885552
113CTBP1_25329375_ChIP-Seq_LNCAP_Human1.11661442
114SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.10412507
115TP53_18474530_ChIP-ChIP_U2OS_Human1.08461320
116ARNT_22903824_ChIP-Seq_MCF-7_Human1.07788027
117SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.07311408
118PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.06898477
119MYC_18940864_ChIP-ChIP_HL60_Human1.05986385
120PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.05499653
121ETV1_20927104_ChIP-Seq_GIST48_Human1.05390104
122CDX2_22108803_ChIP-Seq_LS180_Human1.04601986
123AHR_22903824_ChIP-Seq_MCF-7_Human1.04535937
124EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.04439807
125CTBP2_25329375_ChIP-Seq_LNCAP_Human1.04306417
126ELK1_19687146_ChIP-ChIP_HELA_Human1.04034817
127EZH2_27304074_Chip-Seq_ESCs_Mouse1.03761927
128TDRD3_21172665_ChIP-Seq_MCF-7_Human1.03489755
129POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03198085
130TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03198085
131FLI1_21867929_ChIP-Seq_TH2_Mouse1.03067794
132BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.02708809
133OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01775343
134ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.01294416
135JARID2_20064375_ChIP-Seq_MESCs_Mouse1.01223060
136HOXB7_26014856_ChIP-Seq_BT474_Human0.99978400
137ETV2_25802403_ChIP-Seq_MESCs_Mouse0.99711453
138FOXM1_26456572_ChIP-Seq_MCF-7_Human0.99441724
139AUTS2_25519132_ChIP-Seq_293T-REX_Human0.99366444
140LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.96317268
141CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.95116812
142P53_22127205_ChIP-Seq_FIBROBLAST_Human0.95113470
143RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.94031209
144CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.93572130
145IKZF1_21737484_ChIP-ChIP_HCT116_Human0.92803869
146TOP2B_26459242_ChIP-Seq_MCF-7_Human0.91963250
147PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.91924987
148STAT3_23295773_ChIP-Seq_U87_Human0.91745144
149FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.88244947

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color3.83335800
2MP0001188_hyperpigmentation3.82622923
3MP0006292_abnormal_olfactory_placode3.60743317
4MP0002653_abnormal_ependyma_morphology3.48895953
5MP0008875_abnormal_xenobiotic_pharmacok3.14485085
6MP0000566_synostosis3.08441238
7MP0005646_abnormal_pituitary_gland3.06767237
8MP0002132_abnormal_respiratory_system3.03415783
9MP0002277_abnormal_respiratory_mucosa2.99951728
10MP0003195_calcinosis2.96223611
11MP0005171_absent_coat_pigmentation2.75164848
12MP0008058_abnormal_DNA_repair2.40533733
13MP0005551_abnormal_eye_electrophysiolog2.37925962
14MP0002102_abnormal_ear_morphology2.33952258
15MP0004782_abnormal_surfactant_physiolog2.33321813
16MP0005645_abnormal_hypothalamus_physiol2.33165792
17MP0004043_abnormal_pH_regulation2.32186082
18MP0002638_abnormal_pupillary_reflex2.25025007
19MP0001485_abnormal_pinna_reflex2.18115088
20MP0009046_muscle_twitch2.11534443
21MP0000569_abnormal_digit_pigmentation2.11154970
22MP0004381_abnormal_hair_follicle2.09265988
23MP0003941_abnormal_skin_development2.00634559
24MP0008872_abnormal_physiological_respon1.99623489
25MP0009697_abnormal_copulation1.95921776
26MP0001968_abnormal_touch/_nociception1.94437509
27MP0003724_increased_susceptibility_to1.93164286
28MP0001986_abnormal_taste_sensitivity1.90184751
29MP0002837_dystrophic_cardiac_calcinosis1.90046530
30MP0009745_abnormal_behavioral_response1.84801603
31MP0002148_abnormal_hypersensitivity_rea1.74135085
32MP0006072_abnormal_retinal_apoptosis1.66354470
33MP0001501_abnormal_sleep_pattern1.66065411
34MP0001835_abnormal_antigen_presentation1.65358759
35MP0002876_abnormal_thyroid_physiology1.61562869
36MP0002160_abnormal_reproductive_system1.60265177
37MP0010030_abnormal_orbit_morphology1.59283887
38MP0003787_abnormal_imprinting1.57559823
39MP0008004_abnormal_stomach_pH1.54719141
40MP0002272_abnormal_nervous_system1.52860559
41MP0005409_darkened_coat_color1.52510347
42MP0004885_abnormal_endolymph1.51972385
43MP0000372_irregular_coat_pigmentation1.51835042
44MP0004133_heterotaxia1.51497187
45MP0002735_abnormal_chemical_nociception1.50695044
46MP0010386_abnormal_urinary_bladder1.49370104
47MP0009785_altered_susceptibility_to1.49101929
48MP0000383_abnormal_hair_follicle1.45585194
49MP0003646_muscle_fatigue1.45043359
50MP0002163_abnormal_gland_morphology1.43960988
51MP0005389_reproductive_system_phenotype1.39484528
52MP0001919_abnormal_reproductive_system1.35852928
53MP0001486_abnormal_startle_reflex1.33503136
54MP0005075_abnormal_melanosome_morpholog1.30762271
55MP0003786_premature_aging1.30729756
56MP0005377_hearing/vestibular/ear_phenot1.29630606
57MP0003878_abnormal_ear_physiology1.29630606
58MP0002572_abnormal_emotion/affect_behav1.27721340
59MP0004142_abnormal_muscle_tone1.27650998
60MP0003011_delayed_dark_adaptation1.26982172
61MP0006276_abnormal_autonomic_nervous1.24719402
62MP0000015_abnormal_ear_pigmentation1.24715599
63MP0008007_abnormal_cellular_replicative1.23995447
64MP0008877_abnormal_DNA_methylation1.22730487
65MP0002249_abnormal_larynx_morphology1.22655638
66MP0008057_abnormal_DNA_replication1.22494234
67MP0005379_endocrine/exocrine_gland_phen1.22232122
68MP0000427_abnormal_hair_cycle1.21261190
69MP0002064_seizures1.19618945
70MP0002557_abnormal_social/conspecific_i1.18802979
71MP0000026_abnormal_inner_ear1.18200752
72MP0005248_abnormal_Harderian_gland1.16238211
73MP0009764_decreased_sensitivity_to1.15932687
74MP0001970_abnormal_pain_threshold1.13986039
75MP0002419_abnormal_innate_immunity1.13936857
76MP0005670_abnormal_white_adipose1.12208360
77MP0000049_abnormal_middle_ear1.10394281
78MP0005671_abnormal_response_to1.09546350
79MP0000516_abnormal_urinary_system1.08196466
80MP0005367_renal/urinary_system_phenotyp1.08196466
81MP0000613_abnormal_salivary_gland1.07890627
82MP0002909_abnormal_adrenal_gland1.07658047
83MP0005195_abnormal_posterior_eye1.07174836
84MP0003186_abnormal_redox_activity1.06805214
85MP0002734_abnormal_mechanical_nocicepti1.05733770
86MP0008995_early_reproductive_senescence1.02834711
87MP0001119_abnormal_female_reproductive1.02785055
88MP0002938_white_spotting1.02040031
89MP0003698_abnormal_male_reproductive1.01739312
90MP0002138_abnormal_hepatobiliary_system1.01669229
91MP0005084_abnormal_gallbladder_morpholo0.99483995
92MP0003635_abnormal_synaptic_transmissio0.99028293
93MP0004742_abnormal_vestibular_system0.98984442
94MP0000681_abnormal_thyroid_gland0.98983375
95MP0002067_abnormal_sensory_capabilities0.98948688
96MP0002928_abnormal_bile_duct0.98296504
97MP0003693_abnormal_embryo_hatching0.97816546
98MP0003880_abnormal_central_pattern0.97795307
99MP0002736_abnormal_nociception_after0.97771714
100MP0004019_abnormal_vitamin_homeostasis0.97413637
101MP0001346_abnormal_lacrimal_gland0.97190845
102MP0000678_abnormal_parathyroid_gland0.96977655
103MP0001790_abnormal_immune_system0.96771660
104MP0005387_immune_system_phenotype0.96771660
105MP0002282_abnormal_trachea_morphology0.95744596
106MP0001984_abnormal_olfaction0.95318503
107MP0002733_abnormal_thermal_nociception0.95241348
108MP0003111_abnormal_nucleus_morphology0.95203926
109MP0004145_abnormal_muscle_electrophysio0.94736250
110MP0002229_neurodegeneration0.94122448
111MP0001186_pigmentation_phenotype0.93134264
112MP0001529_abnormal_vocalization0.92057629
113MP0001765_abnormal_ion_homeostasis0.92035872
114MP0001502_abnormal_circadian_rhythm0.91602946
115MP0001929_abnormal_gametogenesis0.91564280
116MP0002095_abnormal_skin_pigmentation0.91262573
117MP0002751_abnormal_autonomic_nervous0.91180172
118MP0009780_abnormal_chondrocyte_physiolo0.89625982
119MP0002234_abnormal_pharynx_morphology0.89508681
120MP0002452_abnormal_antigen_presenting0.88720089
121MP0001905_abnormal_dopamine_level0.88058614
122MP0003718_maternal_effect0.87465985
123MP0000490_abnormal_crypts_of0.85353725
124MP0005410_abnormal_fertilization0.84767761
125MP0004215_abnormal_myocardial_fiber0.84689715
126MP0004924_abnormal_behavior0.84365567
127MP0005386_behavior/neurological_phenoty0.84365567
128MP0002063_abnormal_learning/memory/cond0.84134398
129MP0002752_abnormal_somatic_nervous0.84123231
130MP0005000_abnormal_immune_tolerance0.83704346
131MP0005423_abnormal_somatic_nervous0.83579644
132MP0001963_abnormal_hearing_physiology0.83275525
133MP0000230_abnormal_systemic_arterial0.83184665
134MP0002693_abnormal_pancreas_physiology0.82833179
135MP0000470_abnormal_stomach_morphology0.82406820
136MP0001324_abnormal_eye_pigmentation0.81841741
137MP0005647_abnormal_sex_gland0.81309823
138MP0010094_abnormal_chromosome_stability0.80990425
139MP0005394_taste/olfaction_phenotype0.80835138
140MP0005499_abnormal_olfactory_system0.80835138
141MP0005025_abnormal_response_to0.79971555
142MP0003937_abnormal_limbs/digits/tail_de0.79798972
143MP0003890_abnormal_embryonic-extraembry0.76762409
144MP0005085_abnormal_gallbladder_physiolo0.76481625
145MP0003121_genomic_imprinting0.76363488
146MP0001177_atelectasis0.74502433
147MP0008789_abnormal_olfactory_epithelium0.74098036
148MP0002723_abnormal_immune_serum0.73951895
149MP0003436_decreased_susceptibility_to0.73084363
150MP0000631_abnormal_neuroendocrine_gland0.72186911
151MP0005174_abnormal_tail_pigmentation0.70786978
152MP0002210_abnormal_sex_determination0.69673205
153MP0001286_abnormal_eye_development0.68893012
154MP0001819_abnormal_immune_cell0.66831512
155MP0001800_abnormal_humoral_immune0.66811591
156MP0001853_heart_inflammation0.66409174
157MP0008932_abnormal_embryonic_tissue0.66095536
158MP0005253_abnormal_eye_physiology0.65875707
159MP0002420_abnormal_adaptive_immunity0.64302399
160MP0006082_CNS_inflammation0.63705574
161MP0002177_abnormal_outer_ear0.63649941
162MP0008260_abnormal_autophagy0.63354259
163MP0002075_abnormal_coat/hair_pigmentati0.63300973

Predicted human phenotypes

RankGene SetZ-score
1Abnormal ciliary motility (HP:0012262)7.52036349
2Abnormal respiratory motile cilium physiology (HP:0012261)7.00207728
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)6.38726833
4Abnormal respiratory motile cilium morphology (HP:0005938)5.44698312
5Abnormal respiratory epithelium morphology (HP:0012253)5.44698312
6Rhinitis (HP:0012384)5.20282522
7Dynein arm defect of respiratory motile cilia (HP:0012255)4.42769222
8Absent/shortened dynein arms (HP:0200106)4.42769222
9Chromosomal breakage induced by crosslinking agents (HP:0003221)4.40521243
10Chromsome breakage (HP:0040012)3.98303912
11True hermaphroditism (HP:0010459)3.93475110
12Pancreatic fibrosis (HP:0100732)3.63287965
13Bronchiectasis (HP:0002110)3.28285803
14Chronic bronchitis (HP:0004469)3.25352205
15Pancreatic cysts (HP:0001737)3.09953747
16Occipital encephalocele (HP:0002085)2.78869179
17Congenital stationary night blindness (HP:0007642)2.78380540
18Septo-optic dysplasia (HP:0100842)2.73814933
19Nephronophthisis (HP:0000090)2.67085857
20Nasal polyposis (HP:0100582)2.66543794
21Tubular atrophy (HP:0000092)2.64942205
22Medial flaring of the eyebrow (HP:0010747)2.63280216
23Abolished electroretinogram (ERG) (HP:0000550)2.58885880
24Abnormal drinking behavior (HP:0030082)2.57206875
25Polydipsia (HP:0001959)2.57206875
26Median cleft lip (HP:0000161)2.57199288
27Optic neuritis (HP:0100653)2.56133374
28Retrobulbar optic neuritis (HP:0100654)2.56133374
29Attenuation of retinal blood vessels (HP:0007843)2.55949064
30Decreased circulating renin level (HP:0003351)2.51618924
31Congenital hepatic fibrosis (HP:0002612)2.50131869
32Recurrent sinusitis (HP:0011108)2.49886580
33Preaxial hand polydactyly (HP:0001177)2.49559272
34Tubulointerstitial nephritis (HP:0001970)2.47240304
35Bile duct proliferation (HP:0001408)2.45959507
36Abnormal biliary tract physiology (HP:0012439)2.45959507
37Nephrogenic diabetes insipidus (HP:0009806)2.45569896
38Duplicated collecting system (HP:0000081)2.45421924
39Furrowed tongue (HP:0000221)2.44316781
40Postaxial foot polydactyly (HP:0001830)2.43136387
41Abnormality of the renal medulla (HP:0100957)2.40209575
42Male pseudohermaphroditism (HP:0000037)2.39087189
43Thyroid-stimulating hormone excess (HP:0002925)2.36715172
44Chronic hepatic failure (HP:0100626)2.35651128
45Pendular nystagmus (HP:0012043)2.31778986
46Abnormality of the renal collecting system (HP:0004742)2.31542988
47Aplasia/Hypoplasia of the spleen (HP:0010451)2.30880892
48Absent rod-and cone-mediated responses on ERG (HP:0007688)2.30503176
49Abnormal rod and cone electroretinograms (HP:0008323)2.29222606
50Type II lissencephaly (HP:0007260)2.23592411
51Congenital primary aphakia (HP:0007707)2.21597663
52Gaze-evoked nystagmus (HP:0000640)2.21211781
53Febrile seizures (HP:0002373)2.20359704
54Increased corneal curvature (HP:0100692)2.20233073
55Keratoconus (HP:0000563)2.20233073
56Infertility (HP:0000789)2.19966021
57Bronchitis (HP:0012387)2.17272658
58Hyperventilation (HP:0002883)2.15733166
59Optic nerve hypoplasia (HP:0000609)2.14044614
60Type I transferrin isoform profile (HP:0003642)2.11246785
61Prostate neoplasm (HP:0100787)2.10576477
62Gait imbalance (HP:0002141)2.09737724
63Aplasia/Hypoplasia of the fovea (HP:0008060)2.09632512
64Hypoplasia of the fovea (HP:0007750)2.09632512
65Congenital sensorineural hearing impairment (HP:0008527)2.09349961
66Hypothermia (HP:0002045)2.09161992
67Chronic otitis media (HP:0000389)2.07305079
68Recurrent abscess formation (HP:0002722)2.06457136
69Abnormality of macular pigmentation (HP:0008002)2.06448691
70Abnormality of molar (HP:0011077)2.06311415
71Abnormality of molar morphology (HP:0011070)2.06311415
72Microvesicular hepatic steatosis (HP:0001414)2.05048925
73Supernumerary spleens (HP:0009799)2.03518881
74Progressive cerebellar ataxia (HP:0002073)2.02277582
75Conical tooth (HP:0000698)1.99892966
76Meckel diverticulum (HP:0002245)1.99147454
77Abnormality of the dental root (HP:0006486)1.98646618
78Taurodontia (HP:0000679)1.98646618
79Abnormality of permanent molar morphology (HP:0011071)1.98646618
80Facial cleft (HP:0002006)1.96714037
81Polyuria (HP:0000103)1.95623751
82Abnormality of the nasal mucosa (HP:0000433)1.95375917
83Genetic anticipation (HP:0003743)1.94585684
84Orchitis (HP:0100796)1.93846198
85Type 2 muscle fiber atrophy (HP:0003554)1.93455500
86Obstructive lung disease (HP:0006536)1.91925965
87Chronic obstructive pulmonary disease (HP:0006510)1.91925965
88Postaxial hand polydactyly (HP:0001162)1.91597895
89Abnormality of the ileum (HP:0001549)1.89847489
90Bony spicule pigmentary retinopathy (HP:0007737)1.88876808
91Renal cortical cysts (HP:0000803)1.88685984
92Osteomalacia (HP:0002749)1.88474546
93Abnormality of the preputium (HP:0100587)1.86159938
94Atelectasis (HP:0100750)1.85336716
95Cystic liver disease (HP:0006706)1.83495463
96Aplasia/Hypoplasia of the lens (HP:0008063)1.82719543
97Vaginal atresia (HP:0000148)1.82478989
98Oligohydramnios (HP:0001562)1.81648169
99Abnormality of midbrain morphology (HP:0002418)1.80924433
100Molar tooth sign on MRI (HP:0002419)1.80924433
101Aplasia/Hypoplasia of the tongue (HP:0010295)1.80455178
102Aplasia/Hypoplasia of the uvula (HP:0010293)1.79730978
103Abnormality of the dental pulp (HP:0006479)1.78613213
104Clubbing of toes (HP:0100760)1.76762146
105Abnormality of the renal cortex (HP:0011035)1.76621811
106Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.76097578
107Oculomotor apraxia (HP:0000657)1.75897187
108Pulmonary artery stenosis (HP:0004415)1.75049182
109Asplenia (HP:0001746)1.74708202
110White forelock (HP:0002211)1.74355014
1113-Methylglutaconic aciduria (HP:0003535)1.73887626
112Duplication of thumb phalanx (HP:0009942)1.73472181
113Anencephaly (HP:0002323)1.73073992
114Alveolar cell carcinoma (HP:0006519)1.71010243
115Increased IgM level (HP:0003496)1.70747122
116Abnormality of the fovea (HP:0000493)1.70592950
117Ectopic kidney (HP:0000086)1.69603971
118Patchy hypopigmentation of hair (HP:0011365)1.68944601
119Stomach cancer (HP:0012126)1.68218882
120Abnormality of incisor morphology (HP:0011063)1.67466050
121Tubulointerstitial abnormality (HP:0001969)1.66835736
122Chorioretinal coloboma (HP:0000567)1.66162796
123Inability to walk (HP:0002540)1.65840536
124Congenital, generalized hypertrichosis (HP:0004540)1.65759724
125Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.64966818
126Abnormality of alanine metabolism (HP:0010916)1.64966818
127Hyperalaninemia (HP:0003348)1.64966818
128Decreased central vision (HP:0007663)1.64855207
129Broad-based gait (HP:0002136)1.64776489
130Abnormality of renin-angiotensin system (HP:0000847)1.64465816
131Aganglionic megacolon (HP:0002251)1.64027864
132Mediastinal lymphadenopathy (HP:0100721)1.62876101
133Poor coordination (HP:0002370)1.62606689
134Retinitis pigmentosa (HP:0000510)1.62482611
135Disproportionate short-trunk short stature (HP:0003521)1.62477957
136Severe visual impairment (HP:0001141)1.60820574
137Renal dysplasia (HP:0000110)1.60653401
138Optic nerve coloboma (HP:0000588)1.60282658
139Chorioretinal atrophy (HP:0000533)1.59902032
140Large for gestational age (HP:0001520)1.59643322
141Sclerocornea (HP:0000647)1.59340861
142Carpal bone hypoplasia (HP:0001498)1.58313869
143Chronic sinusitis (HP:0011109)1.57238160
144Genital tract atresia (HP:0001827)1.56825443
145Birth length less than 3rd percentile (HP:0003561)1.56716050
146Recurrent pneumonia (HP:0006532)1.55918545
147Absent speech (HP:0001344)1.55774257
148Recurrent otitis media (HP:0000403)1.55202970
149Methylmalonic acidemia (HP:0002912)1.52718771
150Abnormal urine output (HP:0012590)1.52060176
151Acute necrotizing encephalopathy (HP:0006965)1.48960178
152Cerebellar dysplasia (HP:0007033)1.47862278
153Lissencephaly (HP:0001339)1.47698707
154Abnormality of renal excretion (HP:0011036)1.47690148
155Progressive inability to walk (HP:0002505)1.46485005

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.78794932
2IRAK34.50672823
3CASK4.10692776
4PRPF4B3.06159021
5MAP4K23.04950907
6STK162.97069960
7ZAK2.80658486
8MAP3K142.73371105
9MKNK22.59644683
10PLK42.55591450
11IRAK42.50665497
12TNIK2.25645038
13ACVR1B2.11885753
14TXK2.03684538
15GRK12.02177309
16WNK42.01142211
17IRAK11.90207878
18BMPR21.89132254
19EIF2AK21.85664065
20SIK31.83963355
21TAOK21.83927761
22OXSR11.72375444
23MAP3K41.70170195
24MKNK11.64736443
25IRAK21.60042325
26MAPK151.58187039
27NEK61.56922264
28TIE11.55787501
29STK391.50825502
30MST41.48848887
31ERBB31.48446889
32TAOK31.44525857
33AKT31.39423958
34VRK11.31847924
35PNCK1.28545479
36MAPKAPK31.27668402
37YES11.25123642
38BMPR1B1.24212084
39STK38L1.22292008
40CDK31.22281517
41IKBKB1.21737059
42SRPK11.20931819
43BUB11.20900173
44TEC1.13665655
45PBK1.09938989
46ADRBK21.08143384
47NUAK11.07887326
48ADRBK11.07210989
49NME11.07120267
50PTK2B1.02682398
51GRK71.02313651
52PAK30.97449842
53SGK20.96297979
54DAPK20.93729968
55BCR0.91238437
56MAP2K70.89975735
57BLK0.89076028
58PLK20.87918942
59PINK10.87431759
60MAPKAPK50.86891652
61BRSK20.86847382
62PHKG20.84796641
63PHKG10.84796641
64CSNK1G20.82918947
65PIM20.81620435
66MAP3K120.81176479
67TRIM280.81161516
68INSRR0.80501860
69WNK30.79491003
70IKBKE0.78058940
71MUSK0.77443825
72MAPK130.77396853
73CAMKK20.76330136
74CDK80.75981803
75TLK10.75308616
76CSNK1G10.74291130
77CSNK1A1L0.73099552
78LMTK20.70577953
79PRKCQ0.69708649
80PIK3CG0.69297838
81PRKCI0.69067440
82CSNK1G30.68638424
83TRPM70.67098191
84TGFBR10.67025649
85EIF2AK30.66880554
86NLK0.66162575
87RIPK40.65765559
88BRAF0.65493669
89CHUK0.64387920
90MAPK70.62588038
91STK240.61882888
92CLK10.59280072
93TTK0.58451882
94ATR0.56745744
95ITK0.55650983
96PRKCE0.54877598
97PASK0.54329427
98CAMK2A0.52009021
99BCKDK0.51358764
100NTRK30.49933304
101FGFR20.48855175
102PIK3CA0.47852738
103MARK10.47681089
104SGK2230.47337718
105SGK4940.47337718
106PRKACA0.47048014
107TNK20.46631614
108PRKAA20.46133708
109CSNK1A10.44842268
110EPHA20.44757320
111LYN0.44650814
112WEE10.44506863
113PLK30.43373488
114CDK70.43298360
115OBSCN0.42768502
116BRD40.42364118
117CSNK1D0.41925251
118PIM10.40822446
119PRKCZ0.40765326
120PKN10.40458815
121PLK10.40155486
122EPHA30.40073953
123RPS6KA50.39972513
124MAP3K70.39926845
125PRKCA0.39178147
126STK110.38963882
127ERBB20.38830519
128JAK30.38372370
129MAP2K10.37951153
130TSSK60.37876501
131CAMK10.35683722
132FER0.34967984
133STK30.34670875
134MAP2K60.34023810
135PRKCG0.33635005
136RPS6KA40.33436456
137DYRK20.32989153
138TAF10.32632484
139CSNK2A10.32625757
140TGFBR20.32293666
141SGK10.31874529
142EPHA40.31393496
143PRKG10.30565567
144KIT0.30391413
145VRK20.30371670
146BRSK10.30318668
147BTK0.29488203
148DYRK1A0.29448642
149PRKAA10.29135901
150SGK30.28864906
151JAK10.28217031
152MYLK0.28098333
153TBK10.27136834

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034603.06067080
2Linoleic acid metabolism_Homo sapiens_hsa005912.86360295
3Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.75446534
4Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.56694272
5Homologous recombination_Homo sapiens_hsa034402.51650691
6Caffeine metabolism_Homo sapiens_hsa002322.40163042
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.32737779
8Chemical carcinogenesis_Homo sapiens_hsa052042.16400008
9Nitrogen metabolism_Homo sapiens_hsa009102.13721237
10Butanoate metabolism_Homo sapiens_hsa006502.10703281
11Graft-versus-host disease_Homo sapiens_hsa053322.09813110
12RNA polymerase_Homo sapiens_hsa030202.09232035
13Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.03227925
14NF-kappa B signaling pathway_Homo sapiens_hsa040642.01883141
15Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.96059887
16Maturity onset diabetes of the young_Homo sapiens_hsa049501.96051109
17Tryptophan metabolism_Homo sapiens_hsa003801.95659971
18Pyrimidine metabolism_Homo sapiens_hsa002401.94927203
19Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.93475747
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.93042930
21Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.89546969
22Autoimmune thyroid disease_Homo sapiens_hsa053201.87457258
23Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.85664481
24Allograft rejection_Homo sapiens_hsa053301.83563780
25SNARE interactions in vesicular transport_Homo sapiens_hsa041301.81577074
26Base excision repair_Homo sapiens_hsa034101.81162108
27Rheumatoid arthritis_Homo sapiens_hsa053231.77063350
28Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.72548792
29Selenocompound metabolism_Homo sapiens_hsa004501.72542453
30Histidine metabolism_Homo sapiens_hsa003401.68612846
31Nucleotide excision repair_Homo sapiens_hsa034201.66476928
32Intestinal immune network for IgA production_Homo sapiens_hsa046721.65890379
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.57195790
34Mismatch repair_Homo sapiens_hsa034301.57102301
35DNA replication_Homo sapiens_hsa030301.53495322
36Purine metabolism_Homo sapiens_hsa002301.50379197
37Basal transcription factors_Homo sapiens_hsa030221.49936969
38Proteasome_Homo sapiens_hsa030501.49652472
39Protein export_Homo sapiens_hsa030601.46497747
40Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.46445776
41Nicotine addiction_Homo sapiens_hsa050331.46198800
42NOD-like receptor signaling pathway_Homo sapiens_hsa046211.45883566
43Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.41800152
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.38843834
45Hematopoietic cell lineage_Homo sapiens_hsa046401.38414047
46beta-Alanine metabolism_Homo sapiens_hsa004101.37721744
47Arachidonic acid metabolism_Homo sapiens_hsa005901.36503656
48Leishmaniasis_Homo sapiens_hsa051401.36050545
49ABC transporters_Homo sapiens_hsa020101.32978659
50RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.31250546
51Sphingolipid metabolism_Homo sapiens_hsa006001.30472462
52Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.30425981
53Peroxisome_Homo sapiens_hsa041461.29973639
54Primary bile acid biosynthesis_Homo sapiens_hsa001201.25982902
55Toll-like receptor signaling pathway_Homo sapiens_hsa046201.25929754
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.25162108
57Measles_Homo sapiens_hsa051621.21371168
58Type I diabetes mellitus_Homo sapiens_hsa049401.18705018
59Huntingtons disease_Homo sapiens_hsa050161.15582060
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.13689738
61Phototransduction_Homo sapiens_hsa047441.10754081
62Asthma_Homo sapiens_hsa053101.10390868
63Malaria_Homo sapiens_hsa051441.09805144
64Non-homologous end-joining_Homo sapiens_hsa034501.09303126
65Phagosome_Homo sapiens_hsa041451.07894308
66Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.06574882
67Herpes simplex infection_Homo sapiens_hsa051681.02562028
68Collecting duct acid secretion_Homo sapiens_hsa049661.01448766
69Propanoate metabolism_Homo sapiens_hsa006400.98016624
70Oxidative phosphorylation_Homo sapiens_hsa001900.96109910
71RNA degradation_Homo sapiens_hsa030180.95813034
72Insulin secretion_Homo sapiens_hsa049110.94579360
73Taste transduction_Homo sapiens_hsa047420.94519015
74African trypanosomiasis_Homo sapiens_hsa051430.93677094
75Ribosome_Homo sapiens_hsa030100.91619644
76Other glycan degradation_Homo sapiens_hsa005110.91204482
77Salivary secretion_Homo sapiens_hsa049700.90234558
78Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.87906015
79Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.87871242
80Cardiac muscle contraction_Homo sapiens_hsa042600.87478389
81GABAergic synapse_Homo sapiens_hsa047270.87443130
82Legionellosis_Homo sapiens_hsa051340.87427092
83Spliceosome_Homo sapiens_hsa030400.86775728
84Glycerolipid metabolism_Homo sapiens_hsa005610.86601704
85TNF signaling pathway_Homo sapiens_hsa046680.84478541
86One carbon pool by folate_Homo sapiens_hsa006700.83934424
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82952779
88Circadian entrainment_Homo sapiens_hsa047130.81451611
89Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.79852011
90Vitamin digestion and absorption_Homo sapiens_hsa049770.78713129
91Regulation of autophagy_Homo sapiens_hsa041400.78633461
92Glutamatergic synapse_Homo sapiens_hsa047240.78493527
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.76062648
94Jak-STAT signaling pathway_Homo sapiens_hsa046300.76039896
95Tyrosine metabolism_Homo sapiens_hsa003500.75625305
96Dorso-ventral axis formation_Homo sapiens_hsa043200.75407576
97Influenza A_Homo sapiens_hsa051640.75368147
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.72179925
99Primary immunodeficiency_Homo sapiens_hsa053400.70186645
100Pertussis_Homo sapiens_hsa051330.69499105
101Fatty acid degradation_Homo sapiens_hsa000710.69415742
102Sulfur metabolism_Homo sapiens_hsa009200.68142836
103Ovarian steroidogenesis_Homo sapiens_hsa049130.64497379
104Epstein-Barr virus infection_Homo sapiens_hsa051690.64450941
105Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64098499
106Circadian rhythm_Homo sapiens_hsa047100.62391003
107Glycosaminoglycan degradation_Homo sapiens_hsa005310.61577137
108Basal cell carcinoma_Homo sapiens_hsa052170.59216845
109Morphine addiction_Homo sapiens_hsa050320.58334350
110Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.55609968
111Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.54833086
112Tuberculosis_Homo sapiens_hsa051520.54532868
113Phenylalanine metabolism_Homo sapiens_hsa003600.54466403
114Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52826127
115Glutathione metabolism_Homo sapiens_hsa004800.51387904
116Cell cycle_Homo sapiens_hsa041100.51279811
117Calcium signaling pathway_Homo sapiens_hsa040200.50039505
118Glycerophospholipid metabolism_Homo sapiens_hsa005640.47049264
119Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.46164290
120Parkinsons disease_Homo sapiens_hsa050120.46027735
121Serotonergic synapse_Homo sapiens_hsa047260.44860830
122Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.43787828
123Retinol metabolism_Homo sapiens_hsa008300.43104962
124Mineral absorption_Homo sapiens_hsa049780.42900235
125Ether lipid metabolism_Homo sapiens_hsa005650.42766255
126Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.42072308
127Vibrio cholerae infection_Homo sapiens_hsa051100.41924332
128p53 signaling pathway_Homo sapiens_hsa041150.40929235
129Apoptosis_Homo sapiens_hsa042100.40497593
130Fat digestion and absorption_Homo sapiens_hsa049750.40128094
131Steroid hormone biosynthesis_Homo sapiens_hsa001400.39572267
132Staphylococcus aureus infection_Homo sapiens_hsa051500.38558871
133Vascular smooth muscle contraction_Homo sapiens_hsa042700.37129011
134Alzheimers disease_Homo sapiens_hsa050100.35816725
135Cocaine addiction_Homo sapiens_hsa050300.35771645
136Chemokine signaling pathway_Homo sapiens_hsa040620.35591772
137Hedgehog signaling pathway_Homo sapiens_hsa043400.33757640
138Olfactory transduction_Homo sapiens_hsa047400.33432643
139Osteoclast differentiation_Homo sapiens_hsa043800.33325342
140Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.33076435
141Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.32390216
142HTLV-I infection_Homo sapiens_hsa051660.31839107
143Hepatitis B_Homo sapiens_hsa051610.30783398
144Dopaminergic synapse_Homo sapiens_hsa047280.30675195
145cAMP signaling pathway_Homo sapiens_hsa040240.29900687
146Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.29689214
147Melanoma_Homo sapiens_hsa052180.29245780
148Amphetamine addiction_Homo sapiens_hsa050310.28908040
149Metabolic pathways_Homo sapiens_hsa011000.28338062
150Hepatitis C_Homo sapiens_hsa051600.27992531

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