LRRFIP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)4.85080985
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.32424298
3response to peptidoglycan (GO:0032494)4.12810926
4regulation of interleukin-12 biosynthetic process (GO:0045075)4.10720547
5antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.05971786
6antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.05971786
7positive thymic T cell selection (GO:0045059)3.92720001
8antigen processing and presentation of endogenous antigen (GO:0019883)3.85108547
9macrophage activation involved in immune response (GO:0002281)3.66996136
10regulation of gamma-delta T cell differentiation (GO:0045586)3.65441514
11detection of other organism (GO:0098543)3.62777490
12positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.61642577
13regulation of gamma-delta T cell activation (GO:0046643)3.55933283
14negative T cell selection (GO:0043383)3.50826165
15negative thymic T cell selection (GO:0045060)3.50036810
16leukocyte aggregation (GO:0070486)3.46461123
17negative regulation of T cell mediated immunity (GO:0002710)3.46197071
18negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.45638500
19negative regulation of cell killing (GO:0031342)3.45638500
20detection of molecule of bacterial origin (GO:0032490)3.39593094
21regulation of B cell receptor signaling pathway (GO:0050855)3.37706104
22Arp2/3 complex-mediated actin nucleation (GO:0034314)3.36533009
23detection of bacterium (GO:0016045)3.36030358
24negative regulation of lymphocyte mediated immunity (GO:0002707)3.28709053
25neutrophil activation (GO:0042119)3.28034836
26thymic T cell selection (GO:0045061)3.27018860
27detection of external biotic stimulus (GO:0098581)3.24245609
28positive regulation of granulocyte differentiation (GO:0030854)3.17821740
29interferon-gamma production (GO:0032609)3.15757000
30hepatocyte apoptotic process (GO:0097284)3.14501300
31neutrophil mediated immunity (GO:0002446)3.14261425
32cell adhesion mediated by integrin (GO:0033627)3.13827753
33response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.12720444
34response to host immune response (GO:0052572)3.12720444
35response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.12015224
36response to host (GO:0075136)3.12015224
37response to host defenses (GO:0052200)3.12015224
38microglial cell activation (GO:0001774)3.11952479
39positive regulation of mast cell activation (GO:0033005)3.11161325
40myeloid cell activation involved in immune response (GO:0002275)3.10681788
41positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.07603575
42positive T cell selection (GO:0043368)3.04253552
43regulation of mast cell degranulation (GO:0043304)3.00914271
44macrophage activation (GO:0042116)2.99259226
45granulocyte activation (GO:0036230)2.96984127
46regulation of mast cell activation (GO:0033003)2.96351786
47regulation of tolerance induction (GO:0002643)2.95851002
48negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.93336543
49negative regulation of erythrocyte differentiation (GO:0045647)2.91932145
50detection of biotic stimulus (GO:0009595)2.89910833
51negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.89080023
52negative regulation of T-helper cell differentiation (GO:0045623)2.89080023
53NIK/NF-kappaB signaling (GO:0038061)2.88944244
54regulation of regulatory T cell differentiation (GO:0045589)2.88889767
55defense response to protozoan (GO:0042832)2.87328881
56T cell selection (GO:0045058)2.87293761
57negative regulation of leukocyte mediated immunity (GO:0002704)2.86806426
58positive regulation of natural killer cell differentiation (GO:0032825)2.86138176
59response to interleukin-15 (GO:0070672)2.86103718
60hypotonic response (GO:0006971)2.85853656
61positive regulation of tolerance induction (GO:0002645)2.85851867
62leukocyte cell-cell adhesion (GO:0007159)2.84804962
63B cell mediated immunity (GO:0019724)2.84645809
64response to muramyl dipeptide (GO:0032495)2.83921633
65regulation of mast cell activation involved in immune response (GO:0033006)2.82643513
66regulation of interferon-beta biosynthetic process (GO:0045357)2.79411944
67cellular extravasation (GO:0045123)2.76257948
68response to type I interferon (GO:0034340)2.75929213
69actin nucleation (GO:0045010)2.73725883
70regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.73204880
71positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.72707525
72positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.72339895
73type I interferon signaling pathway (GO:0060337)2.70596476
74cellular response to type I interferon (GO:0071357)2.70596476
75activated T cell proliferation (GO:0050798)2.70151117
76regulation of T cell tolerance induction (GO:0002664)2.67665661
77negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.67414354
78positive regulation of isotype switching (GO:0045830)2.67066118
79antigen receptor-mediated signaling pathway (GO:0050851)2.66771311
80positive regulation of macrophage differentiation (GO:0045651)2.65534939
81positive regulation of interferon-alpha production (GO:0032727)2.64880261
82positive regulation by symbiont of host defense response (GO:0052509)2.64803726
83modulation by symbiont of host defense response (GO:0052031)2.64803726
84modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.64803726
85modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.64803726
86positive regulation by organism of defense response of other organism involved in symbiotic interact2.64803726
87modulation by symbiont of host immune response (GO:0052553)2.64803726
88glomerular visceral epithelial cell development (GO:0072015)2.64761638
89mast cell activation (GO:0045576)2.64760512
90regulation of alpha-beta T cell proliferation (GO:0046640)2.64300305
91positive regulation of mast cell activation involved in immune response (GO:0033008)2.64015358
92positive regulation of mast cell degranulation (GO:0043306)2.64015358
93regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.63858544
94regulation of T cell mediated cytotoxicity (GO:0001914)2.63600083
95T cell migration (GO:0072678)2.63127435
96regulation of B cell differentiation (GO:0045577)2.62557116
97positive regulation of alpha-beta T cell proliferation (GO:0046641)2.55403810
98JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.54710681
99regulation of necroptotic process (GO:0060544)2.54117498
100interferon-gamma-mediated signaling pathway (GO:0060333)2.53611053
101antigen processing and presentation via MHC class Ib (GO:0002475)2.53096474
102regulation of interferon-alpha production (GO:0032647)2.52668886
103immunoglobulin mediated immune response (GO:0016064)2.52065529
104growth hormone receptor signaling pathway (GO:0060396)2.50287657
105T cell costimulation (GO:0031295)2.49890384
106regulation of response to interferon-gamma (GO:0060330)2.49368486
107regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.48936888
108heterotypic cell-cell adhesion (GO:0034113)2.48126230
109neutrophil activation involved in immune response (GO:0002283)2.48030628
110positive regulation of lamellipodium assembly (GO:0010592)2.47774482
111angiogenesis involved in wound healing (GO:0060055)2.47365662
112B cell receptor signaling pathway (GO:0050853)2.46668692
113tyrosine phosphorylation of STAT protein (GO:0007260)2.46299663
114myeloid dendritic cell activation (GO:0001773)2.45769807
115tolerance induction (GO:0002507)2.45026428
116negative regulation of interleukin-12 production (GO:0032695)2.44825666
117positive regulation of B cell differentiation (GO:0045579)2.44465829
118establishment of endothelial barrier (GO:0061028)2.44373501
119lymphocyte costimulation (GO:0031294)2.43663245
120cellular response to interleukin-15 (GO:0071350)2.43496101
121regulation of dendritic cell antigen processing and presentation (GO:0002604)2.41045493
122regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.40691528
123pinocytosis (GO:0006907)2.40424452
124myeloid dendritic cell differentiation (GO:0043011)2.39576856
125wound healing, spreading of cells (GO:0044319)2.39113458
126response to protozoan (GO:0001562)2.38955356
127negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.38862268
128substrate-dependent cell migration (GO:0006929)2.37913116
129negative regulation of phagocytosis (GO:0050765)2.37388357
130wound healing, spreading of epidermal cells (GO:0035313)2.37189863
131fibroblast migration (GO:0010761)2.36106215
132germinal center formation (GO:0002467)2.35160367
133positive regulation of lamellipodium organization (GO:1902745)2.35134044
134regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.34813354
135positive regulation of humoral immune response (GO:0002922)2.34089119
136response to laminar fluid shear stress (GO:0034616)2.31895162
137positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.30842446
138positive regulation of interleukin-2 production (GO:0032743)2.28800454
139positive regulation of immunoglobulin mediated immune response (GO:0002891)2.28042349
140positive regulation of B cell mediated immunity (GO:0002714)2.28042349
141positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.27711944
142natural killer cell activation (GO:0030101)2.27027044
143T cell apoptotic process (GO:0070231)2.26761510
144regulation of type I interferon-mediated signaling pathway (GO:0060338)2.26483758
145natural killer cell differentiation (GO:0001779)2.26040588
146membrane raft organization (GO:0031579)2.24459372
147regulation of T cell receptor signaling pathway (GO:0050856)2.22942036
148skin morphogenesis (GO:0043589)2.22925754

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.98277208
2* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.54776621
3BP1_19119308_ChIP-ChIP_Hs578T_Human4.08322222
4EGR1_19374776_ChIP-ChIP_THP-1_Human3.99577049
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.81850573
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.78048828
7IRF8_21731497_ChIP-ChIP_J774_Mouse3.03670370
8* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.81807770
9* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.80013190
10STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.78424889
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.69097977
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.65563406
13E2F7_22180533_ChIP-Seq_HELA_Human2.57070164
14SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.52355921
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.48747308
16RUNX_20019798_ChIP-Seq_JUKART_Human2.44545878
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.39004352
18* IRF8_27001747_Chip-Seq_BMDM_Mouse2.36761739
19* MYC_22102868_ChIP-Seq_BL_Human2.35588662
20RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.31446844
21* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.26311333
22* MYB_26560356_Chip-Seq_TH2_Human2.21181911
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.15305771
24TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.15139718
25SMAD_19615063_ChIP-ChIP_OVARY_Human2.14011658
26STAT4_19710469_ChIP-ChIP_TH1__Mouse2.09602268
27* MAF_26560356_Chip-Seq_TH1_Human2.08429085
28FOXM1_23109430_ChIP-Seq_U2OS_Human2.07879376
29* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.97331939
30SCL_19346495_ChIP-Seq_HPC-7_Human1.92206600
31* MYB_26560356_Chip-Seq_TH1_Human1.91985338
32TCF7_22412390_ChIP-Seq_EML_Mouse1.87123738
33RARG_19884340_ChIP-ChIP_MEFs_Mouse1.86413200
34Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.86148029
35SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.84593625
36* UTX_26944678_Chip-Seq_JUKART_Human1.83100749
37VDR_21846776_ChIP-Seq_THP-1_Human1.82570388
38GATA2_21666600_ChIP-Seq_HMVEC_Human1.74669090
39ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.74578177
40SPI1_23547873_ChIP-Seq_NB4_Human1.73067056
41VDR_24763502_ChIP-Seq_THP-1_Human1.67599590
42* RUNX1_22412390_ChIP-Seq_EML_Mouse1.64322784
43* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.63193141
44SPI1_23127762_ChIP-Seq_K562_Human1.61166325
45* ELK3_25401928_ChIP-Seq_HUVEC_Human1.60043464
46SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.59267888
47SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.59267888
48SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.52442385
49BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.50335476
50NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.47221745
51GATA1_22025678_ChIP-Seq_K562_Human1.46587838
52KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.45274033
53TRIM28_21343339_ChIP-Seq_HEK293_Human1.43093291
54NOTCH1_21737748_ChIP-Seq_TLL_Human1.42150089
55STAT6_21828071_ChIP-Seq_BEAS2B_Human1.40908860
56GATA3_27048872_Chip-Seq_THYMUS_Human1.40538781
57* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.39620494
58SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.39454020
59CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.37964393
60* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.37469015
61CLOCK_20551151_ChIP-Seq_293T_Human1.36811931
62KDM2B_26808549_Chip-Seq_SUP-B15_Human1.36720620
63* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.36527153
64* PU_27001747_Chip-Seq_BMDM_Mouse1.35657924
65LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.33215447
66HIF1A_21447827_ChIP-Seq_MCF-7_Human1.32457953
67KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.32268354
68ESR1_20079471_ChIP-ChIP_T-47D_Human1.30794345
69* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.29785076
70KDM2B_26808549_Chip-Seq_DND41_Human1.29360161
71PPAR_26484153_Chip-Seq_NCI-H1993_Human1.29063150
72FOXO3_23340844_ChIP-Seq_DLD1_Human1.27577317
73GATA1_19941827_ChIP-Seq_MEL_Mouse1.25177184
74LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.24901883
75GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.23888930
76VDR_24787735_ChIP-Seq_THP-1_Human1.22337312
77* BRD4_25478319_ChIP-Seq_HGPS_Human1.19313531
78CJUN_26792858_Chip-Seq_BT549_Human1.16960255
79SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15615097
80NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.14901323
81* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.14239346
82* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.14103136
83STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.13953520
84PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13475497
85RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13441854
86* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.11585032
87GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.10480524
88GATA1_19941826_ChIP-Seq_K562_Human1.10377058
89CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.09573088
90ELF1_17652178_ChIP-ChIP_JURKAT_Human1.08545621
91CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.07588644
92GATA2_22383799_ChIP-Seq_G1ME_Mouse1.06970435
93* ATF3_27146783_Chip-Seq_COLON_Human1.06802731
94GATA2_19941826_ChIP-Seq_K562_Human1.06251769
95MAF_26560356_Chip-Seq_TH2_Human1.05720583
96CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.04129688
97ESR1_21235772_ChIP-Seq_MCF-7_Human1.03871851
98RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.00733222
99ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.98526586
100KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.96772533
101* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.96352704
102CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96265395
103UBF1/2_26484160_Chip-Seq_HMECs_Human0.95855431
104CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95311606
105NCOR1_26117541_ChIP-Seq_K562_Human0.95265639
106ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.95077010
107* TBX20_22080862_ChIP-Seq_HEART_Mouse0.94968431
108* TBX20_22328084_ChIP-Seq_HEART_Mouse0.94968431
109GATA1_22383799_ChIP-Seq_G1ME_Mouse0.94948504
110CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94027499
111* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.91837948
112PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.91765650
113* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.91564504
114* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.91258757
115TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.91233235
116SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.90551455
117VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.90298489
118* GATA3_26560356_Chip-Seq_TH2_Human0.89779183
119CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89029361
120FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.88843919
121* SMRT_27268052_Chip-Seq_Bcells_Human0.88127907
122PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87705179
123GATA1_19941827_ChIP-Seq_MEL86_Mouse0.84261824
124PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.82611661
125VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.77530660
126ZNF217_24962896_ChIP-Seq_MCF-7_Human0.77199991
127FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.77185778
128GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75185049

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004510_myositis2.68141603
2MP0001835_abnormal_antigen_presentation2.67230061
3MP0003436_decreased_susceptibility_to2.54547512
4MP0003303_peritoneal_inflammation2.37721813
5MP0000685_abnormal_immune_system2.35922339
6MP0003300_gastrointestinal_ulcer2.29510654
7MP0010352_gastrointestinal_tract_polyps2.28892917
8MP0003566_abnormal_cell_adhesion2.26880790
9MP0005671_abnormal_response_to2.14559059
10MP0009785_altered_susceptibility_to2.11999295
11MP0003763_abnormal_thymus_physiology2.09842021
12MP0005000_abnormal_immune_tolerance2.00206156
13MP0001800_abnormal_humoral_immune1.99004900
14MP0002396_abnormal_hematopoietic_system1.98743914
15MP0004808_abnormal_hematopoietic_stem1.96301160
16MP0003705_abnormal_hypodermis_morpholog1.95189202
17MP0002452_abnormal_antigen_presenting1.93280145
18MP0002166_altered_tumor_susceptibility1.93173879
19MP0001790_abnormal_immune_system1.89538172
20MP0005387_immune_system_phenotype1.89538172
21MP0002006_tumorigenesis1.83687929
22MP0003279_aneurysm1.83565621
23MP0002419_abnormal_innate_immunity1.81800092
24MP0003091_abnormal_cell_migration1.77936469
25MP0002405_respiratory_system_inflammati1.77610111
26MP0002420_abnormal_adaptive_immunity1.76880280
27MP0001819_abnormal_immune_cell1.76204707
28MP0002723_abnormal_immune_serum1.75555449
29MP0005023_abnormal_wound_healing1.74396545
30MP0005025_abnormal_response_to1.71627087
31MP0004947_skin_inflammation1.69765066
32MP0003191_abnormal_cellular_cholesterol1.68137887
33MP0001873_stomach_inflammation1.67922786
34MP0002933_joint_inflammation1.64934284
35MP0002877_abnormal_melanocyte_morpholog1.63493209
36MP0002148_abnormal_hypersensitivity_rea1.61723900
37MP0002398_abnormal_bone_marrow1.60103944
38MP0000858_altered_metastatic_potential1.58459005
39MP0005464_abnormal_platelet_physiology1.57969347
40MP0003828_pulmonary_edema1.56890087
41MP0010155_abnormal_intestine_physiology1.56826219
42MP0009278_abnormal_bone_marrow1.52146893
43MP0000569_abnormal_digit_pigmentation1.52085397
44MP0003448_altered_tumor_morphology1.52013676
45MP0008438_abnormal_cutaneous_collagen1.50099994
46MP0001533_abnormal_skeleton_physiology1.49122812
47MP0004381_abnormal_hair_follicle1.48223301
48MP0001853_heart_inflammation1.47773105
49MP0005076_abnormal_cell_differentiation1.45881068
50MP0002138_abnormal_hepatobiliary_system1.44682518
51MP0009333_abnormal_splenocyte_physiolog1.43846823
52MP0005397_hematopoietic_system_phenotyp1.42788838
53MP0001545_abnormal_hematopoietic_system1.42788838
54MP0000716_abnormal_immune_system1.42708639
55MP0005451_abnormal_body_composition1.41852198
56MP0004084_abnormal_cardiac_muscle1.41676829
57MP0003724_increased_susceptibility_to1.41609692
58MP0001958_emphysema1.39432662
59MP0004883_abnormal_blood_vessel1.37439377
60MP0006054_spinal_hemorrhage1.36320300
61MP0003172_abnormal_lysosome_physiology1.36042320
62MP0010368_abnormal_lymphatic_system1.35247877
63MP0002132_abnormal_respiratory_system1.34203036
64MP0006082_CNS_inflammation1.33351836
65MP0002722_abnormal_immune_system1.31546324
66MP0000689_abnormal_spleen_morphology1.31171566
67MP0003646_muscle_fatigue1.30000448
68MP0000343_altered_response_to1.28922848
69MP0001845_abnormal_inflammatory_respons1.28568986
70MP0005164_abnormal_response_to1.28544779
71MP0000733_abnormal_muscle_development1.27259653
72MP0010234_abnormal_vibrissa_follicle1.26764747
73MP0000465_gastrointestinal_hemorrhage1.25104061
74MP0003045_fibrosis1.21243572
75MP0002429_abnormal_blood_cell1.21169238
76MP0000767_abnormal_smooth_muscle1.18793617
77MP0009764_decreased_sensitivity_to1.17517351
78MP0000703_abnormal_thymus_morphology1.14549972
79MP0003183_abnormal_peptide_metabolism1.10688804
80MP0003453_abnormal_keratinocyte_physiol1.10600644
81MP0000490_abnormal_crypts_of1.08074593
82MP0005075_abnormal_melanosome_morpholog1.06786332
83MP0002998_abnormal_bone_remodeling1.05235935
84MP0010307_abnormal_tumor_latency1.04087623
85MP0008260_abnormal_autophagy1.03963939
86MP0000750_abnormal_muscle_regeneration1.03546076
87MP0001851_eye_inflammation1.02020205
88MP0004185_abnormal_adipocyte_glucose0.99666934
89MP0003656_abnormal_erythrocyte_physiolo0.98171948
90MP0005390_skeleton_phenotype0.96892712
91MP0004130_abnormal_muscle_cell0.96379788
92MP0005275_abnormal_skin_tensile0.95691515
93MP0010630_abnormal_cardiac_muscle0.93603333
94MP0002009_preneoplasia0.93224033
95MP0004087_abnormal_muscle_fiber0.89573661
96MP0005623_abnormal_meninges_morphology0.86553995
97MP0003866_abnormal_defecation0.85686070
98MP0002060_abnormal_skin_morphology0.85432807
99MP0000749_muscle_degeneration0.85402159
100MP0009763_increased_sensitivity_to0.84894156
101MP0002019_abnormal_tumor_incidence0.84857151
102MP0001243_abnormal_dermal_layer0.84416540
103MP0008469_abnormal_protein_level0.84066999
104MP0003075_altered_response_to0.83880570
105MP0003950_abnormal_plasma_membrane0.82818405
106MP0002332_abnormal_exercise_endurance0.82217776
107MP0001915_intracranial_hemorrhage0.80802899
108MP0008057_abnormal_DNA_replication0.80407342
109MP0009384_cardiac_valve_regurgitation0.80299338
110MP0005310_abnormal_salivary_gland0.77159787
111MP0000249_abnormal_blood_vessel0.76914279
112MP0001879_abnormal_lymphatic_vessel0.76761124
113MP0002128_abnormal_blood_circulation0.76727976
114MP0008007_abnormal_cellular_replicative0.76163803
115MP0003795_abnormal_bone_structure0.75569849
116MP0000015_abnormal_ear_pigmentation0.74306786
117MP0001663_abnormal_digestive_system0.72971562
118MP0004264_abnormal_extraembryonic_tissu0.71186630
119MP0003693_abnormal_embryo_hatching0.69986186
120MP0005166_decreased_susceptibility_to0.69642907
121MP0005330_cardiomyopathy0.69376690
122MP0002925_abnormal_cardiovascular_devel0.68866317
123MP0003252_abnormal_bile_duct0.68335384
124MP0008004_abnormal_stomach_pH0.68122130
125MP0004484_altered_response_of0.66710311
126MP0005621_abnormal_cell_physiology0.66639482
127MP0009115_abnormal_fat_cell0.65963898
128MP0009765_abnormal_xenobiotic_induced0.64269700
129MP0005058_abnormal_lysosome_morphology0.63625733
130MP0001765_abnormal_ion_homeostasis0.62919178
131MP0005666_abnormal_adipose_tissue0.62660411

Predicted human phenotypes

RankGene SetZ-score
1Myositis (HP:0100614)3.77370658
2Eczematoid dermatitis (HP:0000976)3.71613442
3Recurrent abscess formation (HP:0002722)3.56107331
4Aortic aneurysm (HP:0004942)3.37894939
5Prolonged bleeding time (HP:0003010)3.27075854
6Orchitis (HP:0100796)3.20778817
7Recurrent bacterial skin infections (HP:0005406)3.10624263
8Panhypogammaglobulinemia (HP:0003139)3.09250620
9Increased density of long bones (HP:0006392)3.07562653
10Granulocytopenia (HP:0001913)3.04796123
11Retrobulbar optic neuritis (HP:0100654)3.04415490
12Optic neuritis (HP:0100653)3.04415490
13Gingival bleeding (HP:0000225)3.03895380
14Autoimmune hemolytic anemia (HP:0001890)3.02700400
15Elevated erythrocyte sedimentation rate (HP:0003565)2.98376092
16Epistaxis (HP:0000421)2.97698781
17Encephalitis (HP:0002383)2.90450412
18Aortic dissection (HP:0002647)2.88014094
19Protrusio acetabuli (HP:0003179)2.86687397
20Recurrent fungal infections (HP:0002841)2.84398630
21Obstructive lung disease (HP:0006536)2.82852738
22Chronic obstructive pulmonary disease (HP:0006510)2.82852738
23Arterial thrombosis (HP:0004420)2.82672658
24Agammaglobulinemia (HP:0004432)2.74825505
25Interstitial pulmonary disease (HP:0006530)2.64607924
26Urticaria (HP:0001025)2.60598209
27Increased connective tissue (HP:0009025)2.60390159
28Cerebral aneurysm (HP:0004944)2.54909005
29Abnormality of the fingertips (HP:0001211)2.53611846
30Gastrointestinal inflammation (HP:0004386)2.53070100
31Abnormality of eosinophils (HP:0001879)2.50469676
32Hematochezia (HP:0002573)2.45799083
33Premature rupture of membranes (HP:0001788)2.45511189
34Osteolytic defects of the hand bones (HP:0009699)2.45237331
35Osteolytic defects of the phalanges of the hand (HP:0009771)2.45237331
36Abnormality of B cell number (HP:0010975)2.44221652
37Recurrent viral infections (HP:0004429)2.43738087
38T lymphocytopenia (HP:0005403)2.41348470
39Abnormality of T cell number (HP:0011839)2.39854598
40Persistence of primary teeth (HP:0006335)2.39051363
41Pulmonary embolism (HP:0002204)2.36064822
42Spondylolisthesis (HP:0003302)2.35340155
43Syringomyelia (HP:0003396)2.35253162
44Spinal cord lesions (HP:0100561)2.35253162
45Cervical subluxation (HP:0003308)2.33453977
46Thrombocytosis (HP:0001894)2.31003766
47Absent frontal sinuses (HP:0002688)2.30992965
48Spontaneous hematomas (HP:0007420)2.30526136
49Colitis (HP:0002583)2.29805657
50Mediastinal lymphadenopathy (HP:0100721)2.29760890
51Fatigue (HP:0012378)2.29582135
52Gangrene (HP:0100758)2.28324888
53IgM deficiency (HP:0002850)2.26774972
54Abnormal platelet volume (HP:0011876)2.25742677
55Dilatation of the ascending aorta (HP:0005111)2.23178700
56Type 1 muscle fiber predominance (HP:0003803)2.22702187
57Pustule (HP:0200039)2.22098505
58B lymphocytopenia (HP:0010976)2.21268312
59IgG deficiency (HP:0004315)2.20778092
60Increased IgM level (HP:0003496)2.20440091
61Abnormality of the prostate (HP:0008775)2.20212520
62Peritonitis (HP:0002586)2.18719578
63Right ventricular cardiomyopathy (HP:0011663)2.18633624
64Autoimmune thrombocytopenia (HP:0001973)2.16889330
65Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.16147770
66Pulmonary infiltrates (HP:0002113)2.15122375
67Cellulitis (HP:0100658)2.15012654
68Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.13355006
69Anorexia (HP:0002039)2.12487226
70Keratoconjunctivitis sicca (HP:0001097)2.12150303
71Chronic diarrhea (HP:0002028)2.12062548
72Osteomyelitis (HP:0002754)2.11861837
73Arterial tortuosity (HP:0005116)2.11361523
74Neoplasm of the tracheobronchial system (HP:0100552)2.11148803
75Vascular tortuosity (HP:0004948)2.11033936
76Increased mean platelet volume (HP:0011877)2.08094990
77Hypergammaglobulinemia (HP:0010702)2.07920353
78Verrucae (HP:0200043)2.07414046
79Papilloma (HP:0012740)2.07414046
80Severe combined immunodeficiency (HP:0004430)2.07215347
81Myocardial infarction (HP:0001658)2.07214256
82Recurrent skin infections (HP:0001581)2.07128303
83Abnormality of the nasal mucosa (HP:0000433)2.06773152
84Abnormality of T cells (HP:0002843)2.06631810
85Chronic mucocutaneous candidiasis (HP:0002728)2.06331062
86Recurrent cutaneous fungal infections (HP:0011370)2.06331062
87Radial bowing (HP:0002986)2.05187790
88Skin ulcer (HP:0200042)2.04317585
89Muscle fiber inclusion bodies (HP:0100299)2.03614519
90Distal lower limb amyotrophy (HP:0008944)2.03169798
91Cheilitis (HP:0100825)2.03107528
92Alveolar cell carcinoma (HP:0006519)2.01357801
93Periodontitis (HP:0000704)2.01316748
94Chronic otitis media (HP:0000389)2.01264456
95Papilledema (HP:0001085)2.01031406
96Ankle contracture (HP:0006466)2.00973621
97Abnormality of the pleura (HP:0002103)1.99265509
98Ulnar deviation of the wrist (HP:0003049)1.98365263
99Nasal polyposis (HP:0100582)1.98340882
100Abnormal delayed hypersensitivity skin test (HP:0002963)1.97962203
101Subaortic stenosis (HP:0001682)1.97886907
102Abnormality of the left ventricular outflow tract (HP:0011103)1.97886907
103Subacute progressive viral hepatitis (HP:0006572)1.97665748
104Recurrent bronchitis (HP:0002837)1.97301584
105Acute myeloid leukemia (HP:0004808)1.95938573
106Leukocytosis (HP:0001974)1.95586264
107Increased IgE level (HP:0003212)1.94871187
108Aneurysm (HP:0002617)1.94357163
109Petechiae (HP:0000967)1.93652247
110Hypoplasia of the thymus (HP:0000778)1.93538556
111Vasculitis (HP:0002633)1.92792152
112Difficulty climbing stairs (HP:0003551)1.92386491
113Abnormality of the endocardium (HP:0004306)1.92162198
114Stomatitis (HP:0010280)1.91508744
115Episodic fever (HP:0001954)1.91274556
116Sepsis (HP:0100806)1.90888265
117Viral hepatitis (HP:0006562)1.90660592
118Amyloidosis (HP:0011034)1.90643178
119Keratoconjunctivitis (HP:0001096)1.90507384
120Frequent falls (HP:0002359)1.90328716
121Eosinophilia (HP:0001880)1.89903045
122Ventricular tachycardia (HP:0004756)1.89564713
123Scapular winging (HP:0003691)1.89194088
124Abnormality of the peritoneum (HP:0002585)1.87869865
125Chest pain (HP:0100749)1.87354875
126Meningitis (HP:0001287)1.86789882
127Hemoptysis (HP:0002105)1.86698049
128Abnormality of macrophages (HP:0004311)1.86006650
129Recurrent gram-negative bacterial infections (HP:0005420)1.85490819
130Thyroiditis (HP:0100646)1.84892505
131IgA deficiency (HP:0002720)1.84210129
132Acute hepatic failure (HP:0006554)1.82553024
133Slow saccadic eye movements (HP:0000514)1.82415945
134Glomerulopathy (HP:0100820)1.81717593
135Mitral valve prolapse (HP:0001634)1.80897385
136Gingivitis (HP:0000230)1.80823631
137Skin rash (HP:0000988)1.80771335
138Nemaline bodies (HP:0003798)1.79420751
139Atrophic scars (HP:0001075)1.78509756
140Asymmetric septal hypertrophy (HP:0001670)1.77604686
141Joint swelling (HP:0001386)1.77278868
142Vertigo (HP:0002321)1.76930881
143Bicuspid aortic valve (HP:0001647)1.76105796
144Gastrointestinal infarctions (HP:0005244)1.75009970
145Muscle fiber splitting (HP:0003555)1.73891405
146Facial diplegia (HP:0001349)1.72633471
147Reduced subcutaneous adipose tissue (HP:0003758)1.72012919
148Abnormality of T cell physiology (HP:0011840)1.70287723
149Prostate neoplasm (HP:0100787)1.70111535
150Inflammation of the large intestine (HP:0002037)1.69550491
151Vertebral compression fractures (HP:0002953)1.69077070

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK43.86621598
2MAP4K13.34294876
3TTN3.14827975
4JAK32.43328165
5STK102.43059302
6PKN22.42745513
7TRIB32.32990962
8EEF2K2.22918423
9TXK2.21127924
10MAP3K141.97418331
11TYK21.95754410
12TBK11.92354047
13TRPM71.87329845
14DMPK1.86193198
15ZAP701.78740227
16MAP2K31.75478509
17BMPR21.72062060
18MAP3K131.67278594
19ITK1.64396836
20KIT1.62337277
21TGFBR21.57543644
22RPS6KA41.55449812
23PRPF4B1.55314769
24LRRK21.54041797
25JAK11.53363952
26FGFR41.50090132
27IKBKE1.48613764
28EPHB11.45987173
29TAOK11.44246983
30MAP3K31.43398072
31TEC1.42068762
32STK241.41281810
33LATS11.41035516
34FGFR31.37416079
35NEK91.35496053
36TNK21.27155988
37IKBKB1.26230371
38CSK1.25284841
39EPHA31.23342401
40TAOK31.21963270
41HCK1.19021307
42MOS1.18208194
43BTK1.17700135
44ERN11.13148444
45NLK1.12090121
46PAK41.11241491
47CHUK1.09767673
48FRK1.09344978
49MAP3K11.07434817
50STK31.06864005
51IRAK11.06428691
52NUAK11.06176453
53EPHA21.05673010
54FGR1.04099571
55MAP3K101.03203528
56MATK1.03166827
57TGFBR11.02071648
58PIM11.01280521
59FLT31.00993182
60PIM21.00887329
61BLK0.95576137
62IRAK40.94493897
63CSF1R0.92703878
64PTK60.90828795
65LCK0.90565776
66MAP3K80.90295654
67KDR0.89902125
68SIK30.89895440
69OBSCN0.88773022
70MARK30.86172605
71RIPK10.83732560
72WNK10.83064210
73PDK10.82602276
74SCYL20.82524987
75MAPKAPK30.81288315
76MAP3K20.80586039
77MST40.80265208
78RPS6KB20.78728075
79MYLK0.78400638
80ILK0.78341956
81HIPK20.78076962
82CDK60.77970968
83CDK120.75874782
84MARK20.74583933
85PRKCQ0.73679176
86PRKD20.73598734
87SGK30.72840698
88RAF10.72835990
89PIK3CA0.72654694
90SGK20.72616341
91CDC42BPA0.71042730
92MAPK70.70686690
93PDGFRB0.69416148
94SYK0.69328951
95MAP3K120.68862261
96PTK2B0.68547978
97GRK70.67622162
98MUSK0.66678183
99MAPK120.66583719
100PRKG20.66161477
101GRK60.64669181
102MAP3K50.63935063
103MELK0.62167946
104YES10.62091768
105IRAK30.61458910
106CDK90.61317008
107PAK20.57296425
108BMX0.57238954
109MAPK110.56641138
110NEK20.55648710
111PTK20.55637846
112CDK80.54736224
113JAK20.54070520
114CDK40.53815106
115PIK3CG0.53524922
116PDPK10.53164699
117MAP2K60.50345687
118NME20.50035972
119ABL10.48636610
120CAMK1D0.47962158
121MAPKAPK20.47336357
122ZAK0.46216797
123STK40.46011205
124LYN0.45310572
125PDGFRA0.45187336
126FYN0.44613529
127MAP3K110.42841922
128STK380.42630625
129RPS6KL10.42162754
130RPS6KC10.42162754
131MAP3K70.41671959
132MAP3K60.41569412
133RPS6KA60.41077621
134TAOK20.41072676
135FES0.39613542
136PRKAA20.38058001

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.39465468
2Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.34961927
3Primary immunodeficiency_Homo sapiens_hsa053402.18036618
4NF-kappa B signaling pathway_Homo sapiens_hsa040642.11482742
5Viral myocarditis_Homo sapiens_hsa054162.11101841
6Osteoclast differentiation_Homo sapiens_hsa043801.98759701
7Measles_Homo sapiens_hsa051621.93166547
8Shigellosis_Homo sapiens_hsa051311.82242978
9Graft-versus-host disease_Homo sapiens_hsa053321.77577040
10Leukocyte transendothelial migration_Homo sapiens_hsa046701.74348704
11Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.68617031
12Toxoplasmosis_Homo sapiens_hsa051451.68573275
13B cell receptor signaling pathway_Homo sapiens_hsa046621.68399785
14Malaria_Homo sapiens_hsa051441.65618867
15Hematopoietic cell lineage_Homo sapiens_hsa046401.65094042
16Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.62025215
17Intestinal immune network for IgA production_Homo sapiens_hsa046721.61899999
18TNF signaling pathway_Homo sapiens_hsa046681.60559214
19T cell receptor signaling pathway_Homo sapiens_hsa046601.60491458
20Antigen processing and presentation_Homo sapiens_hsa046121.60034770
21AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.55113337
22Toll-like receptor signaling pathway_Homo sapiens_hsa046201.54269810
23Pancreatic cancer_Homo sapiens_hsa052121.54200575
24Small cell lung cancer_Homo sapiens_hsa052221.51667400
25Jak-STAT signaling pathway_Homo sapiens_hsa046301.49444390
26Adherens junction_Homo sapiens_hsa045201.47925694
27Focal adhesion_Homo sapiens_hsa045101.47210623
28Chronic myeloid leukemia_Homo sapiens_hsa052201.46944824
29Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.45348111
30Allograft rejection_Homo sapiens_hsa053301.45064575
31Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.42820314
32Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.42026474
33Hepatitis B_Homo sapiens_hsa051611.41425267
34NOD-like receptor signaling pathway_Homo sapiens_hsa046211.36896637
35Apoptosis_Homo sapiens_hsa042101.35653972
36Platelet activation_Homo sapiens_hsa046111.34148294
37Legionellosis_Homo sapiens_hsa051341.33817664
38Salmonella infection_Homo sapiens_hsa051321.30129953
39Pertussis_Homo sapiens_hsa051331.28998111
40RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.28743468
41Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.27063251
42Tuberculosis_Homo sapiens_hsa051521.25577854
43ECM-receptor interaction_Homo sapiens_hsa045121.25511971
44Dilated cardiomyopathy_Homo sapiens_hsa054141.24499527
45Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.23640982
46Influenza A_Homo sapiens_hsa051641.23518649
47Herpes simplex infection_Homo sapiens_hsa051681.23378760
48p53 signaling pathway_Homo sapiens_hsa041151.22697254
49Acute myeloid leukemia_Homo sapiens_hsa052211.21606411
50Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.21019125
51Proteoglycans in cancer_Homo sapiens_hsa052051.17742658
52MicroRNAs in cancer_Homo sapiens_hsa052061.14878105
53Amoebiasis_Homo sapiens_hsa051461.12003506
54Regulation of actin cytoskeleton_Homo sapiens_hsa048101.10503559
55HTLV-I infection_Homo sapiens_hsa051661.09407804
56Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.09275421
57Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.05456975
58Chemokine signaling pathway_Homo sapiens_hsa040621.05415715
59Dorso-ventral axis formation_Homo sapiens_hsa043200.99209242
60VEGF signaling pathway_Homo sapiens_hsa043700.96495028
61Transcriptional misregulation in cancer_Homo sapiens_hsa052020.93629999
62Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.91256157
63Prolactin signaling pathway_Homo sapiens_hsa049170.90942203
64HIF-1 signaling pathway_Homo sapiens_hsa040660.89006049
65Viral carcinogenesis_Homo sapiens_hsa052030.88794651
66Staphylococcus aureus infection_Homo sapiens_hsa051500.84849226
67African trypanosomiasis_Homo sapiens_hsa051430.84715496
68Neurotrophin signaling pathway_Homo sapiens_hsa047220.81832943
69Colorectal cancer_Homo sapiens_hsa052100.81765239
70Bladder cancer_Homo sapiens_hsa052190.77301273
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73769968
72FoxO signaling pathway_Homo sapiens_hsa040680.73553231
73Hepatitis C_Homo sapiens_hsa051600.72426104
74Epstein-Barr virus infection_Homo sapiens_hsa051690.70592555
75Other glycan degradation_Homo sapiens_hsa005110.70515889
76Cell cycle_Homo sapiens_hsa041100.69841126
77Rheumatoid arthritis_Homo sapiens_hsa053230.69604530
78Caffeine metabolism_Homo sapiens_hsa002320.68843354
79Phosphatidylinositol signaling system_Homo sapiens_hsa040700.68302461
80TGF-beta signaling pathway_Homo sapiens_hsa043500.66161356
81Non-small cell lung cancer_Homo sapiens_hsa052230.65432643
82Autoimmune thyroid disease_Homo sapiens_hsa053200.61847687
83Rap1 signaling pathway_Homo sapiens_hsa040150.60655693
84Prostate cancer_Homo sapiens_hsa052150.60244020
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.59933333
86Insulin resistance_Homo sapiens_hsa049310.59629481
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.59526008
88Renal cell carcinoma_Homo sapiens_hsa052110.58245756
89Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58171381
90mTOR signaling pathway_Homo sapiens_hsa041500.57445368
91Asthma_Homo sapiens_hsa053100.56276044
92SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55415537
93Pathways in cancer_Homo sapiens_hsa052000.55051370
94Glycosaminoglycan degradation_Homo sapiens_hsa005310.54363172
95Phagosome_Homo sapiens_hsa041450.53569387
96Type I diabetes mellitus_Homo sapiens_hsa049400.53293763
97Thyroid cancer_Homo sapiens_hsa052160.53145859
98PI3K-Akt signaling pathway_Homo sapiens_hsa041510.52492230
99Inositol phosphate metabolism_Homo sapiens_hsa005620.51789882
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.51363290
101Endometrial cancer_Homo sapiens_hsa052130.51237242
102Choline metabolism in cancer_Homo sapiens_hsa052310.51025685
103GnRH signaling pathway_Homo sapiens_hsa049120.49367534
104Phospholipase D signaling pathway_Homo sapiens_hsa040720.48870736
105Endocytosis_Homo sapiens_hsa041440.48810365
106Notch signaling pathway_Homo sapiens_hsa043300.47362732
107Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46813979
108Adipocytokine signaling pathway_Homo sapiens_hsa049200.45542079
109Lysosome_Homo sapiens_hsa041420.44797567
110MAPK signaling pathway_Homo sapiens_hsa040100.44675751
111Glioma_Homo sapiens_hsa052140.44168022
112RNA degradation_Homo sapiens_hsa030180.43529973
113Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43411781
114Thyroid hormone signaling pathway_Homo sapiens_hsa049190.43348168
115Type II diabetes mellitus_Homo sapiens_hsa049300.42847803
116Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.41899921
117Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.40838349
118Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40481984
119ErbB signaling pathway_Homo sapiens_hsa040120.36120408
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.32280208
121Complement and coagulation cascades_Homo sapiens_hsa046100.28614505

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