LRRN2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.94643086
2synaptic vesicle maturation (GO:0016188)5.79537794
3vocalization behavior (GO:0071625)5.78174538
4locomotory exploration behavior (GO:0035641)5.68991299
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.57700876
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.50946309
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.32903935
8regulation of glutamate receptor signaling pathway (GO:1900449)5.10940030
9synaptic vesicle exocytosis (GO:0016079)5.10086408
10ionotropic glutamate receptor signaling pathway (GO:0035235)4.94700577
11protein localization to synapse (GO:0035418)4.87735351
12exploration behavior (GO:0035640)4.84157377
13glutamate secretion (GO:0014047)4.79150348
14regulation of neuronal synaptic plasticity (GO:0048168)4.76188764
15neuron cell-cell adhesion (GO:0007158)4.74856422
16regulation of synaptic vesicle exocytosis (GO:2000300)4.67974020
17regulation of long-term neuronal synaptic plasticity (GO:0048169)4.56483402
18layer formation in cerebral cortex (GO:0021819)4.51937992
19pyrimidine nucleobase catabolic process (GO:0006208)4.51612166
20glutamate receptor signaling pathway (GO:0007215)4.50935224
21regulation of synapse structural plasticity (GO:0051823)4.43698798
22positive regulation of synapse maturation (GO:0090129)4.38988648
23synaptic vesicle docking involved in exocytosis (GO:0016081)4.32404739
24synaptic transmission, glutamatergic (GO:0035249)4.30146549
25regulation of synaptic vesicle transport (GO:1902803)4.22920862
26neuronal action potential propagation (GO:0019227)4.21559265
27neurotransmitter secretion (GO:0007269)4.20220427
28dendritic spine morphogenesis (GO:0060997)4.20069410
29regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.17199928
30neurotransmitter-gated ion channel clustering (GO:0072578)4.09573650
31neuron recognition (GO:0008038)4.08434935
32axonal fasciculation (GO:0007413)4.02774097
33long-term memory (GO:0007616)4.02440558
34sodium ion export (GO:0071436)3.99503913
35axon ensheathment in central nervous system (GO:0032291)3.98364454
36central nervous system myelination (GO:0022010)3.98364454
37neuron-neuron synaptic transmission (GO:0007270)3.97800372
38positive regulation of synapse assembly (GO:0051965)3.96359224
39proline transport (GO:0015824)3.94759534
40behavioral response to nicotine (GO:0035095)3.94648264
41cellular potassium ion homeostasis (GO:0030007)3.92729575
42gamma-aminobutyric acid transport (GO:0015812)3.88193197
43regulation of excitatory postsynaptic membrane potential (GO:0060079)3.84686605
44regulation of dendritic spine morphogenesis (GO:0061001)3.75581941
45regulation of synaptic plasticity (GO:0048167)3.73458294
46positive regulation of membrane potential (GO:0045838)3.71047058
47nucleobase catabolic process (GO:0046113)3.64125155
48cell communication by electrical coupling (GO:0010644)3.63678957
49synaptic vesicle endocytosis (GO:0048488)3.63606459
50regulation of postsynaptic membrane potential (GO:0060078)3.63596681
51protein localization to cilium (GO:0061512)3.60829196
52G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.60024398
53membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.60013969
54transmission of nerve impulse (GO:0019226)3.58012431
55cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.52860173
56postsynaptic membrane organization (GO:0001941)3.51512414
57limb bud formation (GO:0060174)3.51150930
58neuronal ion channel clustering (GO:0045161)3.49408739
59long-term synaptic potentiation (GO:0060291)3.47854090
60central nervous system projection neuron axonogenesis (GO:0021952)3.47670693
61positive regulation of dendritic spine development (GO:0060999)3.47655252
62gamma-aminobutyric acid signaling pathway (GO:0007214)3.45858750
63startle response (GO:0001964)3.43535088
64neurotransmitter transport (GO:0006836)3.43252554
65neuromuscular process controlling balance (GO:0050885)3.42369470
66innervation (GO:0060384)3.41377141
67behavioral defense response (GO:0002209)3.40629443
68behavioral fear response (GO:0001662)3.40629443
69positive regulation of dendritic spine morphogenesis (GO:0061003)3.39804632
70regulation of synapse maturation (GO:0090128)3.38371542
71cerebellar Purkinje cell differentiation (GO:0021702)3.36072504
72regulation of synaptic transmission, glutamatergic (GO:0051966)3.34805288
73regulation of vesicle fusion (GO:0031338)3.32840407
74positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.32751495
75presynaptic membrane organization (GO:0097090)3.32277550
76auditory behavior (GO:0031223)3.30950937
77activation of protein kinase A activity (GO:0034199)3.30316240
78dendrite morphogenesis (GO:0048813)3.29151673
79dendritic spine organization (GO:0097061)3.24328098
80G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.23607840
81positive regulation of synaptic transmission, GABAergic (GO:0032230)3.22776120
82regulation of dendritic spine development (GO:0060998)3.21401985
83regulation of neurotransmitter levels (GO:0001505)3.20836912
84regulation of neurotransmitter secretion (GO:0046928)3.19570344
85learning (GO:0007612)3.19263526
86negative regulation of oligodendrocyte differentiation (GO:0048715)3.17865400
87response to histamine (GO:0034776)3.17466286
88neuromuscular process controlling posture (GO:0050884)3.17401712
89regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.17337535
90response to auditory stimulus (GO:0010996)3.17175744
91mechanosensory behavior (GO:0007638)3.17097598
92fear response (GO:0042596)3.16382934
93negative regulation of synaptic transmission, GABAergic (GO:0032229)3.12892278
94positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.10950702
95regulation of respiratory system process (GO:0044065)3.10703262
96short-term memory (GO:0007614)3.09795871
97membrane depolarization (GO:0051899)3.09612518
98regulation of synapse assembly (GO:0051963)3.06390075
99regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.06315498
100epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.05398146
101regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.04849006
102cell migration in hindbrain (GO:0021535)3.04340275
103retinal ganglion cell axon guidance (GO:0031290)3.03664156
104regulation of synaptic transmission (GO:0050804)3.02995377
105synapse assembly (GO:0007416)3.01843119
106spinal cord development (GO:0021510)2.99821457
107positive regulation of neurotransmitter secretion (GO:0001956)2.99668901
108cerebellar granule cell differentiation (GO:0021707)2.97887386
109membrane depolarization during action potential (GO:0086010)2.96628888
110presynaptic membrane assembly (GO:0097105)2.95682381
111regulation of neurotransmitter transport (GO:0051588)2.94895103
112social behavior (GO:0035176)2.94094872
113intraspecies interaction between organisms (GO:0051703)2.94094872
114negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.91604997
115cerebellar Purkinje cell layer development (GO:0021680)2.91525336
116prepulse inhibition (GO:0060134)2.91501879
117positive regulation of synaptic transmission (GO:0050806)2.91414765
118establishment of mitochondrion localization (GO:0051654)2.90807734
119mating behavior (GO:0007617)2.90234637
120synapse organization (GO:0050808)2.87512775
121neuromuscular synaptic transmission (GO:0007274)2.78085267
122regulation of neurotransmitter uptake (GO:0051580)2.77688004
123negative regulation of astrocyte differentiation (GO:0048712)2.76818348
124central nervous system neuron axonogenesis (GO:0021955)2.73799595
125regulation of synapse organization (GO:0050807)2.73110767
126regulation of respiratory gaseous exchange (GO:0043576)2.71672496
127regulation of voltage-gated calcium channel activity (GO:1901385)2.70160030
128cochlea development (GO:0090102)2.70015234
129neuronal stem cell maintenance (GO:0097150)2.67994806
130adult walking behavior (GO:0007628)2.67949350
131neuron fate determination (GO:0048664)2.66187114
132regulation of Rac GTPase activity (GO:0032314)2.64790401
133serotonin metabolic process (GO:0042428)2.62864335
134calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.62792491

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.10237164
2GBX2_23144817_ChIP-Seq_PC3_Human3.42680234
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.28521279
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.25087548
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.23283733
6* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.85920245
7* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.85920245
8* REST_21632747_ChIP-Seq_MESCs_Mouse2.83123245
9* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.79995892
10* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.74439401
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.71597722
12* EZH2_27304074_Chip-Seq_ESCs_Mouse2.66559089
13RARB_27405468_Chip-Seq_BRAIN_Mouse2.62424213
14* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.61927841
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.59365840
16* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.57938570
17DROSHA_22980978_ChIP-Seq_HELA_Human2.54628235
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.45587039
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.41500222
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.39274581
21* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.38584294
22IKZF1_21737484_ChIP-ChIP_HCT116_Human2.35028003
23* REST_18959480_ChIP-ChIP_MESCs_Mouse2.30404090
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.26018026
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.10646879
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.07005821
27EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.03256603
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.01360971
29AR_21572438_ChIP-Seq_LNCaP_Human1.91582447
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.83428462
31VDR_22108803_ChIP-Seq_LS180_Human1.70003485
32* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.64338308
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.63244626
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.62719357
35PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.53527529
36SMAD4_21799915_ChIP-Seq_A2780_Human1.52736365
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.51569674
38* RING1B_27294783_Chip-Seq_ESCs_Mouse1.46446804
39ZNF274_21170338_ChIP-Seq_K562_Hela1.45723528
40RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.39290439
41TAF15_26573619_Chip-Seq_HEK293_Human1.37985193
42* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.33691990
43* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.33345653
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.32235076
45NR3C1_23031785_ChIP-Seq_PC12_Mouse1.29118403
46DNAJC2_21179169_ChIP-ChIP_NT2_Human1.28451571
47P300_19829295_ChIP-Seq_ESCs_Human1.26853034
48* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23669352
49SOX2_21211035_ChIP-Seq_LN229_Gbm1.23522145
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23388924
51ZFP57_27257070_Chip-Seq_ESCs_Mouse1.21818743
52TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21803702
53* RING1B_27294783_Chip-Seq_NPCs_Mouse1.20962328
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.20354159
55AR_19668381_ChIP-Seq_PC3_Human1.19569415
56WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.17536802
57AR_25329375_ChIP-Seq_VCAP_Human1.16229597
58BMI1_23680149_ChIP-Seq_NPCS_Mouse1.15720509
59* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15702593
60GATA1_26923725_Chip-Seq_HPCs_Mouse1.14761088
61KDM2B_26808549_Chip-Seq_K562_Human1.13374415
62SMAD_19615063_ChIP-ChIP_OVARY_Human1.10288731
63EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.09964041
64* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.09556556
65EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.09432000
66IGF1R_20145208_ChIP-Seq_DFB_Human1.08929535
67TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07504889
68* STAT3_23295773_ChIP-Seq_U87_Human1.06020746
69GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06018214
70OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04143906
71ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.04028916
72P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03821526
73CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.03346967
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.03299292
75TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.02633318
76RNF2_27304074_Chip-Seq_NSC_Mouse1.02038063
77CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.00917344
78LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99416344
79SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99221402
80BCAT_22108803_ChIP-Seq_LS180_Human0.98189095
81CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97710506
82YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97701227
83RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.97461277
84KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.97328263
85ARNT_22903824_ChIP-Seq_MCF-7_Human0.96804455
86* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96365735
87TCF4_23295773_ChIP-Seq_U87_Human0.95580092
88FUS_26573619_Chip-Seq_HEK293_Human0.95027020
89PIAS1_25552417_ChIP-Seq_VCAP_Human0.94319900
90TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.94283821
91POU3F2_20337985_ChIP-ChIP_501MEL_Human0.94159032
92ZNF217_24962896_ChIP-Seq_MCF-7_Human0.93307006
93SMAD3_21741376_ChIP-Seq_ESCs_Human0.93021263
94TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92780539
95GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92690979
96HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.92234800
97SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.91830506
98RUNX2_22187159_ChIP-Seq_PCA_Human0.91585784
99NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91552038
100MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91162094
101PRDM14_20953172_ChIP-Seq_ESCs_Human0.90746226
102CTCF_27219007_Chip-Seq_Bcells_Human0.90651360
103TP53_20018659_ChIP-ChIP_R1E_Mouse0.90075249
104VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.88919864
105* SMAD4_21741376_ChIP-Seq_HESCs_Human0.88882070
106AHR_22903824_ChIP-Seq_MCF-7_Human0.87946344
107CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.87195832
108TET1_21490601_ChIP-Seq_MESCs_Mouse0.87104885
109* TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.86436063
110* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.86092046
111ISL1_27105846_Chip-Seq_CPCs_Mouse0.85989240
112SMAD3_21741376_ChIP-Seq_HESCs_Human0.85390948
113* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.84969376
114* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.84674798
115POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.84470919
116TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84470919
117UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84340571
118* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84339127
119THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.83789861
120GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.83477128
121CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82401289

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.82794242
2MP0003880_abnormal_central_pattern5.02267105
3MP0003635_abnormal_synaptic_transmissio4.25438211
4MP0004270_analgesia3.48727282
5MP0009745_abnormal_behavioral_response3.44016270
6MP0002063_abnormal_learning/memory/cond3.43670416
7MP0005423_abnormal_somatic_nervous3.38861671
8MP0002064_seizures3.14677937
9MP0009046_muscle_twitch2.93123190
10MP0002572_abnormal_emotion/affect_behav2.82334681
11MP0001968_abnormal_touch/_nociception2.74365932
12MP0003136_yellow_coat_color2.67019855
13MP0001486_abnormal_startle_reflex2.49865168
14MP0002822_catalepsy2.47779429
15MP0002272_abnormal_nervous_system2.45393469
16MP0002734_abnormal_mechanical_nocicepti2.37150376
17MP0001501_abnormal_sleep_pattern2.30907920
18MP0001440_abnormal_grooming_behavior2.16214050
19MP0002736_abnormal_nociception_after2.10993712
20MP0002733_abnormal_thermal_nociception2.09569910
21MP0000778_abnormal_nervous_system2.09167063
22MP0000566_synostosis2.07448831
23MP0003329_amyloid_beta_deposits2.06806007
24MP0004858_abnormal_nervous_system2.02354186
25MP0002735_abnormal_chemical_nociception2.00774568
26MP0009780_abnormal_chondrocyte_physiolo1.95240346
27MP0002638_abnormal_pupillary_reflex1.93321669
28MP0002184_abnormal_innervation1.91480164
29MP0001970_abnormal_pain_threshold1.90862802
30MP0002067_abnormal_sensory_capabilities1.85926014
31MP0008569_lethality_at_weaning1.83210542
32MP0006276_abnormal_autonomic_nervous1.82671126
33MP0002909_abnormal_adrenal_gland1.81227787
34MP0004811_abnormal_neuron_physiology1.80398121
35MP0002557_abnormal_social/conspecific_i1.75131129
36MP0004133_heterotaxia1.72507873
37MP0002102_abnormal_ear_morphology1.67123296
38MP0005386_behavior/neurological_phenoty1.65757533
39MP0004924_abnormal_behavior1.65757533
40MP0005646_abnormal_pituitary_gland1.64128371
41MP0000955_abnormal_spinal_cord1.63859848
42MP0005645_abnormal_hypothalamus_physiol1.58824507
43MP0001984_abnormal_olfaction1.55865840
44MP0001485_abnormal_pinna_reflex1.48749510
45MP0004885_abnormal_endolymph1.48355594
46MP0002882_abnormal_neuron_morphology1.45383379
47MP0003787_abnormal_imprinting1.44903772
48MP0002066_abnormal_motor_capabilities/c1.41676926
49MP0003122_maternal_imprinting1.41074819
50MP0005377_hearing/vestibular/ear_phenot1.34855571
51MP0003878_abnormal_ear_physiology1.34855571
52MP0001502_abnormal_circadian_rhythm1.33541367
53MP0003879_abnormal_hair_cell1.32383618
54MP0001529_abnormal_vocalization1.31306237
55MP0003121_genomic_imprinting1.28725262
56MP0003633_abnormal_nervous_system1.26287864
57MP0002928_abnormal_bile_duct1.26008224
58MP0003938_abnormal_ear_development1.23878504
59MP0001905_abnormal_dopamine_level1.23556072
60MP0004142_abnormal_muscle_tone1.23434953
61MP0003011_delayed_dark_adaptation1.19023763
62MP0002152_abnormal_brain_morphology1.18254481
63MP0003631_nervous_system_phenotype1.12889642
64MP0003283_abnormal_digestive_organ1.05192781
65MP0000751_myopathy1.04947420
66MP0004145_abnormal_muscle_electrophysio1.04134195
67MP0002249_abnormal_larynx_morphology1.02423534
68MP0002751_abnormal_autonomic_nervous0.99220271
69MP0004147_increased_porphyrin_level0.96200373
70MP0002069_abnormal_eating/drinking_beha0.95339585
71MP0001188_hyperpigmentation0.94613952
72MP0000631_abnormal_neuroendocrine_gland0.93196898
73MP0000604_amyloidosis0.92036715
74MP0003075_altered_response_to0.91989907
75MP0003632_abnormal_nervous_system0.90737540
76MP0005253_abnormal_eye_physiology0.90587390
77MP0003634_abnormal_glial_cell0.88991208
78MP0006072_abnormal_retinal_apoptosis0.86706491
79MP0002229_neurodegeneration0.86200218
80MP0004085_abnormal_heartbeat0.85928943
81MP0008872_abnormal_physiological_respon0.85764862
82MP0001986_abnormal_taste_sensitivity0.85052925
83MP0008877_abnormal_DNA_methylation0.84916387
84MP0003890_abnormal_embryonic-extraembry0.84643449
85MP0002938_white_spotting0.84508125
86MP0003137_abnormal_impulse_conducting0.82325717
87MP0005535_abnormal_body_temperature0.81538328
88MP0010386_abnormal_urinary_bladder0.81316108
89MP0008961_abnormal_basal_metabolism0.81138239
90MP0003119_abnormal_digestive_system0.81042463
91MP0005551_abnormal_eye_electrophysiolog0.80887910
92MP0005499_abnormal_olfactory_system0.79859443
93MP0005394_taste/olfaction_phenotype0.79859443
94MP0000569_abnormal_digit_pigmentation0.79474621
95MP0008874_decreased_physiological_sensi0.79039061
96MP0005195_abnormal_posterior_eye0.78744066
97MP0001177_atelectasis0.78490608
98MP0003690_abnormal_glial_cell0.78248641
99MP0002752_abnormal_somatic_nervous0.77263330
100MP0001293_anophthalmia0.76917231
101MP0001963_abnormal_hearing_physiology0.75000518
102MP0000049_abnormal_middle_ear0.74753509
103MP0002837_dystrophic_cardiac_calcinosis0.74697853
104MP0010030_abnormal_orbit_morphology0.74529024
105MP0004742_abnormal_vestibular_system0.73435015
106MP0001346_abnormal_lacrimal_gland0.73101814
107MP0004215_abnormal_myocardial_fiber0.72925377
108MP0005248_abnormal_Harderian_gland0.70481012
109MP0005171_absent_coat_pigmentation0.69905698
110MP0004484_altered_response_of0.68888784
111MP0008995_early_reproductive_senescence0.68449661
112MP0000920_abnormal_myelination0.68037735
113MP0003942_abnormal_urinary_system0.67468352
114MP0001664_abnormal_digestion0.66448550
115MP0002653_abnormal_ependyma_morphology0.65993055
116MP0005623_abnormal_meninges_morphology0.65620099
117MP0002234_abnormal_pharynx_morphology0.65576490
118MP0003172_abnormal_lysosome_physiology0.65097596
119MP0000013_abnormal_adipose_tissue0.64864686
120MP0003861_abnormal_nervous_system0.64742391
121MP0002090_abnormal_vision0.64162032
122MP0004233_abnormal_muscle_weight0.63141857
123MP0005409_darkened_coat_color0.62261740
124MP0006292_abnormal_olfactory_placode0.58760858
125MP0004510_myositis0.56615992
126MP0005167_abnormal_blood-brain_barrier0.56174035
127MP0001943_abnormal_respiration0.56024589
128MP0005187_abnormal_penis_morphology0.55743038
129MP0010769_abnormal_survival0.53225513
130MP0000026_abnormal_inner_ear0.51479173

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.49334029
2Myokymia (HP:0002411)6.98821216
3Focal seizures (HP:0007359)5.80914336
4Visual hallucinations (HP:0002367)5.41814397
5Epileptic encephalopathy (HP:0200134)4.74034090
6Progressive cerebellar ataxia (HP:0002073)4.50589775
7Atonic seizures (HP:0010819)4.31110715
8Febrile seizures (HP:0002373)4.15374334
9Absence seizures (HP:0002121)4.06007864
10Action tremor (HP:0002345)4.04953810
11Supranuclear gaze palsy (HP:0000605)3.80746532
12Dialeptic seizures (HP:0011146)3.77114279
13Generalized tonic-clonic seizures (HP:0002069)3.73638841
14Broad-based gait (HP:0002136)3.55678467
15Abnormal eating behavior (HP:0100738)3.35476857
16Impaired vibration sensation in the lower limbs (HP:0002166)3.25414954
17Depression (HP:0000716)3.23162178
18True hermaphroditism (HP:0010459)3.22935878
19Mutism (HP:0002300)3.21019041
20Poor eye contact (HP:0000817)3.20524262
21Ankle clonus (HP:0011448)3.17452501
22Anxiety (HP:0000739)3.13630317
23Cerebral inclusion bodies (HP:0100314)3.12621948
24Hyperventilation (HP:0002883)3.11832237
25Dysdiadochokinesis (HP:0002075)3.08293533
26Dysmetria (HP:0001310)3.05615011
27Truncal ataxia (HP:0002078)3.02612989
28Neurofibrillary tangles (HP:0002185)3.01903720
29Gaze-evoked nystagmus (HP:0000640)3.01113203
30Amblyopia (HP:0000646)2.98993766
31Pancreatic fibrosis (HP:0100732)2.98152917
32Hemiparesis (HP:0001269)2.94835460
33Septo-optic dysplasia (HP:0100842)2.94424077
34Excessive salivation (HP:0003781)2.92330897
35Drooling (HP:0002307)2.92330897
36Abnormality of the lower motor neuron (HP:0002366)2.89838144
37Nephronophthisis (HP:0000090)2.89718499
38Impaired social interactions (HP:0000735)2.89249659
39Abnormal social behavior (HP:0012433)2.89249659
40Megalencephaly (HP:0001355)2.89099412
41Pancreatic cysts (HP:0001737)2.85869633
42Urinary bladder sphincter dysfunction (HP:0002839)2.83254606
43Postural instability (HP:0002172)2.82051979
44Genetic anticipation (HP:0003743)2.81218474
45Molar tooth sign on MRI (HP:0002419)2.75347703
46Abnormality of midbrain morphology (HP:0002418)2.75347703
47Papilledema (HP:0001085)2.70835868
48Torticollis (HP:0000473)2.66778033
49Diplopia (HP:0000651)2.66178594
50Abnormality of binocular vision (HP:0011514)2.66178594
51Type II lissencephaly (HP:0007260)2.61372323
52Split foot (HP:0001839)2.60363546
53Abnormality of the labia minora (HP:0012880)2.59282965
54Hemiplegia (HP:0002301)2.57457685
55Stereotypic behavior (HP:0000733)2.54394803
56Impaired smooth pursuit (HP:0007772)2.53862543
57Urinary urgency (HP:0000012)2.53060920
58Focal dystonia (HP:0004373)2.51624213
59Spastic gait (HP:0002064)2.50205025
60Epileptiform EEG discharges (HP:0011182)2.48997674
61Progressive inability to walk (HP:0002505)2.48235894
62Intention tremor (HP:0002080)2.44627102
63Abnormal ciliary motility (HP:0012262)2.41327762
64Polyphagia (HP:0002591)2.41147341
65Abnormal respiratory motile cilium morphology (HP:0005938)2.40639414
66Abnormal respiratory epithelium morphology (HP:0012253)2.40639414
67Rib fusion (HP:0000902)2.38611028
68Abnormal respiratory motile cilium physiology (HP:0012261)2.38246880
69Ventricular fibrillation (HP:0001663)2.37906634
70Scanning speech (HP:0002168)2.37315573
71EEG with generalized epileptiform discharges (HP:0011198)2.36837542
72Bradykinesia (HP:0002067)2.36233016
73Lissencephaly (HP:0001339)2.33687643
74Termporal pattern (HP:0011008)2.33397389
75Insidious onset (HP:0003587)2.33397389
76Optic nerve hypoplasia (HP:0000609)2.32754619
77Oligodactyly (hands) (HP:0001180)2.30207795
78Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.29641540
79Abnormality of the corticospinal tract (HP:0002492)2.28755208
80Amyotrophic lateral sclerosis (HP:0007354)2.28147466
81Abnormality of ocular smooth pursuit (HP:0000617)2.27067708
82Chronic hepatic failure (HP:0100626)2.26880545
83Retinal dysplasia (HP:0007973)2.23162429
84Aplasia involving bones of the extremities (HP:0009825)2.23145269
85Aplasia involving bones of the upper limbs (HP:0009823)2.23145269
86Aplasia of the phalanges of the hand (HP:0009802)2.23145269
87Hypsarrhythmia (HP:0002521)2.23045365
88Abnormality of the renal medulla (HP:0100957)2.22116877
89Cystic liver disease (HP:0006706)2.22013027
90Fetal akinesia sequence (HP:0001989)2.21863528
91Anophthalmia (HP:0000528)2.21371993
92Insomnia (HP:0100785)2.19981982
93Agitation (HP:0000713)2.19624976
94Status epilepticus (HP:0002133)2.18254943
95Craniofacial dystonia (HP:0012179)2.17329087
96Medial flaring of the eyebrow (HP:0010747)2.14638202
97Obstructive sleep apnea (HP:0002870)2.12122429
98Congenital stationary night blindness (HP:0007642)2.11484235
99Absent speech (HP:0001344)2.11118059
100Lower limb muscle weakness (HP:0007340)2.10175851
101Absent/shortened dynein arms (HP:0200106)2.10174485
102Dynein arm defect of respiratory motile cilia (HP:0012255)2.10174485
103Pointed chin (HP:0000307)2.09841866
104Limb dystonia (HP:0002451)2.09295479
105Impaired vibratory sensation (HP:0002495)2.07906140
106Gait imbalance (HP:0002141)2.07258554
107Cutaneous finger syndactyly (HP:0010554)2.06196876
108Generalized myoclonic seizures (HP:0002123)2.05848157
109Annular pancreas (HP:0001734)2.02047261
110Abnormality of salivation (HP:0100755)1.98923554
111Incomplete penetrance (HP:0003829)1.98042224
112Decreased central vision (HP:0007663)1.98032365
113Abnormal drinking behavior (HP:0030082)1.98012246
114Polydipsia (HP:0001959)1.98012246
115Delusions (HP:0000746)1.97213291
116Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.97109519
117Inability to walk (HP:0002540)1.96441341
118Dysmetric saccades (HP:0000641)1.95398116
119Pachygyria (HP:0001302)1.94744401
120Anencephaly (HP:0002323)1.93821217
121Stomach cancer (HP:0012126)1.93773723
122Abnormal EKG (HP:0003115)1.93446161
123Morphological abnormality of the inner ear (HP:0011390)1.91817760
124Concave nail (HP:0001598)1.89876952
125Occipital encephalocele (HP:0002085)1.89730239
126Blue irides (HP:0000635)1.89394324
127Pheochromocytoma (HP:0002666)1.89046801
128Cerebellar dysplasia (HP:0007033)1.88598522
129Gait ataxia (HP:0002066)1.86092977
130Apathy (HP:0000741)1.84786727
131Postaxial hand polydactyly (HP:0001162)1.84704932
132Narrow forehead (HP:0000341)1.84591799
133Sleep apnea (HP:0010535)1.84366854
134Lower limb asymmetry (HP:0100559)1.83590012
135Absent septum pellucidum (HP:0001331)1.83229119
136Sclerocornea (HP:0000647)1.82755619
137Psychosis (HP:0000709)1.82128013
138Anosmia (HP:0000458)1.81475651
139Specific learning disability (HP:0001328)1.81394151
140Oligodactyly (HP:0012165)1.81347765
141Neuronal loss in central nervous system (HP:0002529)1.80792150
142Rapidly progressive (HP:0003678)1.78349956
143Failure to thrive in infancy (HP:0001531)1.76895709
144Spastic tetraplegia (HP:0002510)1.75514552
145Ulnar claw (HP:0001178)1.74847507
146Lower limb amyotrophy (HP:0007210)1.74036612
147Cutaneous syndactyly (HP:0012725)1.73999301
148Tubular atrophy (HP:0000092)1.73025557
149Rigidity (HP:0002063)1.71336139
150Thickened helices (HP:0000391)1.70203328
151Inappropriate behavior (HP:0000719)1.70138560
152Rhinitis (HP:0012384)1.69915473
153Hypoplasia of the corpus callosum (HP:0002079)1.67637622
154Increased corneal curvature (HP:0100692)1.67383498
155Keratoconus (HP:0000563)1.67383498
156Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.66690051
157Genital tract atresia (HP:0001827)1.66606714
158Narrow nasal bridge (HP:0000446)1.66090352
159Postaxial foot polydactyly (HP:0001830)1.64817349
160Aplasia/Hypoplasia of the brainstem (HP:0007362)1.63936240
161Hypoplasia of the brainstem (HP:0002365)1.63936240

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.82956779
2NTRK34.74504426
3MAP3K93.80725597
4MARK13.33742240
5MINK12.74015980
6MAP3K42.72537018
7PAK62.36069880
8MAPK152.27894332
9PRKD32.24924620
10MAP2K72.24618117
11KSR22.22629211
12NTRK22.20631496
13DAPK22.19741785
14FGFR21.99994076
15DYRK21.97817092
16KSR11.86342795
17RIPK41.84339019
18TNIK1.81548445
19CAMKK11.68211833
20MAP2K41.68004707
21MAP3K121.65754610
22NTRK11.59195984
23CDK51.57007909
24ARAF1.52732884
25WNK31.49599750
26PLK21.49329211
27PRPF4B1.48356439
28FRK1.48013261
29SIK21.46046946
30DAPK11.44225480
31CASK1.43354149
32MAPK131.39825885
33BMPR1B1.38485494
34WNK41.38398274
35GRK51.38307995
36MAP3K131.36454521
37PRKCG1.29631325
38PHKG21.26401756
39PHKG11.26401756
40PNCK1.26374081
41EPHB21.25269536
42EPHA31.25213210
43STK381.22197678
44TYRO31.21481625
45FES1.21171021
46UHMK11.12518692
47TAOK31.10380738
48TSSK61.06922433
49CAMK2A1.06909449
50CDK191.03121445
51LATS20.97770108
52ADRBK20.97570051
53PTK2B0.96630758
54RAF10.94854211
55CDK180.94371586
56CDK150.92678859
57CAMK10.92395665
58LMTK20.91981154
59CAMK2B0.90272581
60PAK30.89512345
61MAP3K20.89390324
62CDK140.88572675
63PRKCH0.82915155
64DYRK1A0.82394115
65STK390.81006592
66CDK11A0.80565138
67ERBB20.80025289
68SGK4940.78188305
69SGK2230.78188305
70MARK20.76513795
71STK110.76008476
72PKN10.75497132
73TAOK10.75247521
74DYRK1B0.75104798
75CAMKK20.74582507
76GRK10.73817472
77ALK0.71201279
78BMPR20.71148678
79TLK10.71036793
80NME10.68452225
81SGK10.66677392
82RET0.66284612
83MAP3K70.65166652
84FGR0.62529877
85PINK10.62185995
86PRKCZ0.61766359
87SGK20.59177419
88TXK0.57803455
89CSNK1G20.55899202
90MAP4K20.54873468
91PDK10.54240688
92RIPK10.54186461
93CSNK1G30.52075752
94TNK20.51886756
95SGK30.51053277
96PRKCE0.50553423
97GRK60.49735767
98CAMK2D0.49577935
99PDPK10.49079252
100OXSR10.48586142
101ROCK20.47637174
102RPS6KA30.47573715
103RPS6KA20.46799233
104FER0.46796751
105MAP3K10.46785358
106CSNK1G10.46563596
107PLK40.46500683
108MAPK100.46368137
109CDK30.45661244
110MAP2K20.44843321
111FYN0.44640353
112CAMK2G0.44587425
113INSRR0.44553398
114CDC42BPA0.44263899
115CAMK40.44216577
116PRKACA0.43272379
117ADRBK10.43128551
118WNK10.39123988
119PRKCQ0.37419877
120NUAK10.36757587
121IRAK20.36721789
122MAP2K10.36497051
123NEK10.36383555
124BRAF0.36231136
125CAMK1G0.35621753
126IRAK10.35056385
127MAPK120.34962875
128SIK30.34037862
129MAP3K60.33892453
130NEK60.33636765
131DYRK30.31965556
132DAPK30.31566851
133CSNK1D0.31554962
134PRKD20.31200713
135DDR20.30744212
136ZAK0.30561732
137PRKCB0.29760422
138PRKCI0.29692237
139PRKG10.29604439
140PRKCA0.28603699

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.88669785
2Synaptic vesicle cycle_Homo sapiens_hsa047213.03341709
3Long-term potentiation_Homo sapiens_hsa047202.77730994
4Circadian entrainment_Homo sapiens_hsa047132.77033113
5GABAergic synapse_Homo sapiens_hsa047272.70927964
6Olfactory transduction_Homo sapiens_hsa047402.69725481
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.68037083
8Glutamatergic synapse_Homo sapiens_hsa047242.64148086
9Amphetamine addiction_Homo sapiens_hsa050312.47373667
10Morphine addiction_Homo sapiens_hsa050322.45296475
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.26709413
12Salivary secretion_Homo sapiens_hsa049702.26547303
13Dopaminergic synapse_Homo sapiens_hsa047282.14499778
14Insulin secretion_Homo sapiens_hsa049111.99107469
15Gastric acid secretion_Homo sapiens_hsa049711.94300053
16Cholinergic synapse_Homo sapiens_hsa047251.88998589
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.86447592
18Taste transduction_Homo sapiens_hsa047421.84494435
19Long-term depression_Homo sapiens_hsa047301.73825647
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.72378353
21Oxytocin signaling pathway_Homo sapiens_hsa049211.68077791
22Calcium signaling pathway_Homo sapiens_hsa040201.67242234
23Renin secretion_Homo sapiens_hsa049241.66969359
24Serotonergic synapse_Homo sapiens_hsa047261.66335256
25Basal cell carcinoma_Homo sapiens_hsa052171.64164071
26Cocaine addiction_Homo sapiens_hsa050301.60221840
27Hedgehog signaling pathway_Homo sapiens_hsa043401.56250674
28GnRH signaling pathway_Homo sapiens_hsa049121.47872395
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.47795838
30Gap junction_Homo sapiens_hsa045401.40955106
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.37802709
32Axon guidance_Homo sapiens_hsa043601.33891039
33cAMP signaling pathway_Homo sapiens_hsa040241.31403331
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.29252976
35Oxidative phosphorylation_Homo sapiens_hsa001901.28797246
36Collecting duct acid secretion_Homo sapiens_hsa049661.27704521
37Glioma_Homo sapiens_hsa052141.19390194
38Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.16876882
39Estrogen signaling pathway_Homo sapiens_hsa049151.16373628
40Melanogenesis_Homo sapiens_hsa049161.15173467
41Type II diabetes mellitus_Homo sapiens_hsa049301.13350449
42Parkinsons disease_Homo sapiens_hsa050121.13141556
43Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12483011
44Phosphatidylinositol signaling system_Homo sapiens_hsa040701.12297084
45Cardiac muscle contraction_Homo sapiens_hsa042601.10845655
46Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.08039425
47Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06576952
48cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06442459
49ErbB signaling pathway_Homo sapiens_hsa040121.02800533
50Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.94716533
51Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93710492
52Butanoate metabolism_Homo sapiens_hsa006500.91406669
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.91310341
54Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.90181819
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.89453801
56Notch signaling pathway_Homo sapiens_hsa043300.88521053
57Oocyte meiosis_Homo sapiens_hsa041140.88193329
58Pancreatic secretion_Homo sapiens_hsa049720.86513708
59Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.84451578
60Vibrio cholerae infection_Homo sapiens_hsa051100.83239797
61Dorso-ventral axis formation_Homo sapiens_hsa043200.82686373
62Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.82021517
63Dilated cardiomyopathy_Homo sapiens_hsa054140.79451058
64Choline metabolism in cancer_Homo sapiens_hsa052310.77759989
65Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.77420442
66Thyroid hormone synthesis_Homo sapiens_hsa049180.77242913
67Nitrogen metabolism_Homo sapiens_hsa009100.76234254
68Hippo signaling pathway_Homo sapiens_hsa043900.75795549
69Ether lipid metabolism_Homo sapiens_hsa005650.75621777
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.72582512
71VEGF signaling pathway_Homo sapiens_hsa043700.70396440
72Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.68534180
73Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.68275158
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.68022795
75Linoleic acid metabolism_Homo sapiens_hsa005910.67850588
76Huntingtons disease_Homo sapiens_hsa050160.66958365
77MAPK signaling pathway_Homo sapiens_hsa040100.65905319
78Phototransduction_Homo sapiens_hsa047440.63636611
79Neurotrophin signaling pathway_Homo sapiens_hsa047220.63138668
80Carbohydrate digestion and absorption_Homo sapiens_hsa049730.63097984
81Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60881078
82Glucagon signaling pathway_Homo sapiens_hsa049220.59822731
83Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59597671
84Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56372710
85Ras signaling pathway_Homo sapiens_hsa040140.55484227
86Bile secretion_Homo sapiens_hsa049760.54971126
87Rap1 signaling pathway_Homo sapiens_hsa040150.54515953
88Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.53713149
89Regulation of autophagy_Homo sapiens_hsa041400.53253483
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.51872844
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.51471709
92Prion diseases_Homo sapiens_hsa050200.49543851
93mTOR signaling pathway_Homo sapiens_hsa041500.49542140
94Endometrial cancer_Homo sapiens_hsa052130.49286663
95Alcoholism_Homo sapiens_hsa050340.48387480
96Inositol phosphate metabolism_Homo sapiens_hsa005620.47555583
97Wnt signaling pathway_Homo sapiens_hsa043100.47161908
98Non-small cell lung cancer_Homo sapiens_hsa052230.44818031
99Endocytosis_Homo sapiens_hsa041440.44150530
100Maturity onset diabetes of the young_Homo sapiens_hsa049500.44110744
101Tryptophan metabolism_Homo sapiens_hsa003800.43617646
102Alzheimers disease_Homo sapiens_hsa050100.43334926
103Circadian rhythm_Homo sapiens_hsa047100.41495450
104ABC transporters_Homo sapiens_hsa020100.41402535
105Type I diabetes mellitus_Homo sapiens_hsa049400.40550543
106Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40136003
107Renal cell carcinoma_Homo sapiens_hsa052110.38491895
108Insulin signaling pathway_Homo sapiens_hsa049100.38019733
109Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.37983729
110Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.36635056
111Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.36553947
112African trypanosomiasis_Homo sapiens_hsa051430.36475330
113Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.36126408
114Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35221184
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.33863266
116Ovarian steroidogenesis_Homo sapiens_hsa049130.31241164
117Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.30617076
118Glycerolipid metabolism_Homo sapiens_hsa005610.29632062
119Colorectal cancer_Homo sapiens_hsa052100.28043478
120Sulfur relay system_Homo sapiens_hsa041220.27840775
121Chemokine signaling pathway_Homo sapiens_hsa040620.25851723
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.24807187
123Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.23331745
124Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.22401877
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.21711047

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