Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.94643086 |
2 | synaptic vesicle maturation (GO:0016188) | 5.79537794 |
3 | vocalization behavior (GO:0071625) | 5.78174538 |
4 | locomotory exploration behavior (GO:0035641) | 5.68991299 |
5 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.57700876 |
6 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.50946309 |
7 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.32903935 |
8 | regulation of glutamate receptor signaling pathway (GO:1900449) | 5.10940030 |
9 | synaptic vesicle exocytosis (GO:0016079) | 5.10086408 |
10 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.94700577 |
11 | protein localization to synapse (GO:0035418) | 4.87735351 |
12 | exploration behavior (GO:0035640) | 4.84157377 |
13 | glutamate secretion (GO:0014047) | 4.79150348 |
14 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.76188764 |
15 | neuron cell-cell adhesion (GO:0007158) | 4.74856422 |
16 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.67974020 |
17 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.56483402 |
18 | layer formation in cerebral cortex (GO:0021819) | 4.51937992 |
19 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.51612166 |
20 | glutamate receptor signaling pathway (GO:0007215) | 4.50935224 |
21 | regulation of synapse structural plasticity (GO:0051823) | 4.43698798 |
22 | positive regulation of synapse maturation (GO:0090129) | 4.38988648 |
23 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.32404739 |
24 | synaptic transmission, glutamatergic (GO:0035249) | 4.30146549 |
25 | regulation of synaptic vesicle transport (GO:1902803) | 4.22920862 |
26 | neuronal action potential propagation (GO:0019227) | 4.21559265 |
27 | neurotransmitter secretion (GO:0007269) | 4.20220427 |
28 | dendritic spine morphogenesis (GO:0060997) | 4.20069410 |
29 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.17199928 |
30 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.09573650 |
31 | neuron recognition (GO:0008038) | 4.08434935 |
32 | axonal fasciculation (GO:0007413) | 4.02774097 |
33 | long-term memory (GO:0007616) | 4.02440558 |
34 | sodium ion export (GO:0071436) | 3.99503913 |
35 | central nervous system myelination (GO:0022010) | 3.98364454 |
36 | axon ensheathment in central nervous system (GO:0032291) | 3.98364454 |
37 | neuron-neuron synaptic transmission (GO:0007270) | 3.97800372 |
38 | positive regulation of synapse assembly (GO:0051965) | 3.96359224 |
39 | proline transport (GO:0015824) | 3.94759534 |
40 | behavioral response to nicotine (GO:0035095) | 3.94648264 |
41 | cellular potassium ion homeostasis (GO:0030007) | 3.92729575 |
42 | gamma-aminobutyric acid transport (GO:0015812) | 3.88193197 |
43 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.84686605 |
44 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.75581941 |
45 | regulation of synaptic plasticity (GO:0048167) | 3.73458294 |
46 | positive regulation of membrane potential (GO:0045838) | 3.71047058 |
47 | nucleobase catabolic process (GO:0046113) | 3.64125155 |
48 | cell communication by electrical coupling (GO:0010644) | 3.63678957 |
49 | synaptic vesicle endocytosis (GO:0048488) | 3.63606459 |
50 | regulation of postsynaptic membrane potential (GO:0060078) | 3.63596681 |
51 | protein localization to cilium (GO:0061512) | 3.60829196 |
52 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.60024398 |
53 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.60013969 |
54 | transmission of nerve impulse (GO:0019226) | 3.58012431 |
55 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.52860173 |
56 | postsynaptic membrane organization (GO:0001941) | 3.51512414 |
57 | limb bud formation (GO:0060174) | 3.51150930 |
58 | neuronal ion channel clustering (GO:0045161) | 3.49408739 |
59 | long-term synaptic potentiation (GO:0060291) | 3.47854090 |
60 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.47670693 |
61 | positive regulation of dendritic spine development (GO:0060999) | 3.47655252 |
62 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.45858750 |
63 | startle response (GO:0001964) | 3.43535088 |
64 | neurotransmitter transport (GO:0006836) | 3.43252554 |
65 | neuromuscular process controlling balance (GO:0050885) | 3.42369470 |
66 | innervation (GO:0060384) | 3.41377141 |
67 | behavioral fear response (GO:0001662) | 3.40629443 |
68 | behavioral defense response (GO:0002209) | 3.40629443 |
69 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.39804632 |
70 | regulation of synapse maturation (GO:0090128) | 3.38371542 |
71 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.36072504 |
72 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.34805288 |
73 | regulation of vesicle fusion (GO:0031338) | 3.32840407 |
74 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.32751495 |
75 | presynaptic membrane organization (GO:0097090) | 3.32277550 |
76 | auditory behavior (GO:0031223) | 3.30950937 |
77 | activation of protein kinase A activity (GO:0034199) | 3.30316240 |
78 | dendrite morphogenesis (GO:0048813) | 3.29151673 |
79 | dendritic spine organization (GO:0097061) | 3.24328098 |
80 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.23607840 |
81 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.22776120 |
82 | regulation of dendritic spine development (GO:0060998) | 3.21401985 |
83 | regulation of neurotransmitter levels (GO:0001505) | 3.20836912 |
84 | regulation of neurotransmitter secretion (GO:0046928) | 3.19570344 |
85 | learning (GO:0007612) | 3.19263526 |
86 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 3.17865400 |
87 | response to histamine (GO:0034776) | 3.17466286 |
88 | neuromuscular process controlling posture (GO:0050884) | 3.17401712 |
89 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.17337535 |
90 | response to auditory stimulus (GO:0010996) | 3.17175744 |
91 | mechanosensory behavior (GO:0007638) | 3.17097598 |
92 | fear response (GO:0042596) | 3.16382934 |
93 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.12892278 |
94 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.10950702 |
95 | regulation of respiratory system process (GO:0044065) | 3.10703262 |
96 | short-term memory (GO:0007614) | 3.09795871 |
97 | membrane depolarization (GO:0051899) | 3.09612518 |
98 | regulation of synapse assembly (GO:0051963) | 3.06390075 |
99 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.06315498 |
100 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.05398146 |
101 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.04849006 |
102 | cell migration in hindbrain (GO:0021535) | 3.04340275 |
103 | retinal ganglion cell axon guidance (GO:0031290) | 3.03664156 |
104 | regulation of synaptic transmission (GO:0050804) | 3.02995377 |
105 | synapse assembly (GO:0007416) | 3.01843119 |
106 | spinal cord development (GO:0021510) | 2.99821457 |
107 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.99668901 |
108 | cerebellar granule cell differentiation (GO:0021707) | 2.97887386 |
109 | membrane depolarization during action potential (GO:0086010) | 2.96628888 |
110 | presynaptic membrane assembly (GO:0097105) | 2.95682381 |
111 | regulation of neurotransmitter transport (GO:0051588) | 2.94895103 |
112 | intraspecies interaction between organisms (GO:0051703) | 2.94094872 |
113 | social behavior (GO:0035176) | 2.94094872 |
114 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.91604997 |
115 | cerebellar Purkinje cell layer development (GO:0021680) | 2.91525336 |
116 | prepulse inhibition (GO:0060134) | 2.91501879 |
117 | positive regulation of synaptic transmission (GO:0050806) | 2.91414765 |
118 | establishment of mitochondrion localization (GO:0051654) | 2.90807734 |
119 | mating behavior (GO:0007617) | 2.90234637 |
120 | synapse organization (GO:0050808) | 2.87512775 |
121 | neuromuscular synaptic transmission (GO:0007274) | 2.78085267 |
122 | regulation of neurotransmitter uptake (GO:0051580) | 2.77688004 |
123 | negative regulation of astrocyte differentiation (GO:0048712) | 2.76818348 |
124 | central nervous system neuron axonogenesis (GO:0021955) | 2.73799595 |
125 | regulation of synapse organization (GO:0050807) | 2.73110767 |
126 | regulation of respiratory gaseous exchange (GO:0043576) | 2.71672496 |
127 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.70160030 |
128 | cochlea development (GO:0090102) | 2.70015234 |
129 | neuronal stem cell maintenance (GO:0097150) | 2.67994806 |
130 | adult walking behavior (GO:0007628) | 2.67949350 |
131 | neuron fate determination (GO:0048664) | 2.66187114 |
132 | regulation of Rac GTPase activity (GO:0032314) | 2.64790401 |
133 | serotonin metabolic process (GO:0042428) | 2.62864335 |
134 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.62792491 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.10237164 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.42680234 |
3 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.28521279 |
4 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.25087548 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.23283733 |
6 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.85920245 |
7 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.85920245 |
8 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.83123245 |
9 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.79995892 |
10 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.74439401 |
11 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.71597722 |
12 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.66559089 |
13 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.62424213 |
14 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.61927841 |
15 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.59365840 |
16 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.57938570 |
17 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.54628235 |
18 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.45587039 |
19 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.41500222 |
20 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.39274581 |
21 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.38584294 |
22 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.35028003 |
23 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.30404090 |
24 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.26018026 |
25 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.10646879 |
26 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.07005821 |
27 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.03256603 |
28 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.01360971 |
29 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.91582447 |
30 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.83428462 |
31 | VDR_22108803_ChIP-Seq_LS180_Human | 1.70003485 |
32 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.64338308 |
33 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.63244626 |
34 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.62719357 |
35 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.53527529 |
36 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.52736365 |
37 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.51569674 |
38 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.46446804 |
39 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.45723528 |
40 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.39290439 |
41 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.37985193 |
42 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.33691990 |
43 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.33345653 |
44 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.32235076 |
45 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.29118403 |
46 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.28451571 |
47 | P300_19829295_ChIP-Seq_ESCs_Human | 1.26853034 |
48 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.23669352 |
49 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.23522145 |
50 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.23388924 |
51 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.21818743 |
52 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21803702 |
53 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.20962328 |
54 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.20354159 |
55 | AR_19668381_ChIP-Seq_PC3_Human | 1.19569415 |
56 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.17536802 |
57 | AR_25329375_ChIP-Seq_VCAP_Human | 1.16229597 |
58 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.15720509 |
59 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.15702593 |
60 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.14761088 |
61 | KDM2B_26808549_Chip-Seq_K562_Human | 1.13374415 |
62 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.10288731 |
63 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.09964041 |
64 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.09556556 |
65 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.09432000 |
66 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.08929535 |
67 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07504889 |
68 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.06020746 |
69 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06018214 |
70 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.04143906 |
71 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.04028916 |
72 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.03821526 |
73 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.03346967 |
74 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.03299292 |
75 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.02633318 |
76 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.02038063 |
77 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.00917344 |
78 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.99416344 |
79 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.99221402 |
80 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.98189095 |
81 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.97710506 |
82 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.97701227 |
83 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.97461277 |
84 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.97328263 |
85 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.96804455 |
86 | * MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.96365735 |
87 | TCF4_23295773_ChIP-Seq_U87_Human | 0.95580092 |
88 | FUS_26573619_Chip-Seq_HEK293_Human | 0.95027020 |
89 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.94319900 |
90 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.94283821 |
91 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.94159032 |
92 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.93307006 |
93 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.93021263 |
94 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.92780539 |
95 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92690979 |
96 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.92234800 |
97 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.91830506 |
98 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.91585784 |
99 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.91552038 |
100 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.91162094 |
101 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.90746226 |
102 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.90651360 |
103 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.90075249 |
104 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.88919864 |
105 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.88882070 |
106 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.87946344 |
107 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.87195832 |
108 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.87104885 |
109 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.86436063 |
110 | * STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.86092046 |
111 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.85989240 |
112 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.85390948 |
113 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.84969376 |
114 | * OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.84674798 |
115 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.84470919 |
116 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.84470919 |
117 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.84340571 |
118 | * SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.84339127 |
119 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.83789861 |
120 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.83477128 |
121 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.82401289 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 6.82794242 |
2 | MP0003880_abnormal_central_pattern | 5.02267105 |
3 | MP0003635_abnormal_synaptic_transmissio | 4.25438211 |
4 | MP0004270_analgesia | 3.48727282 |
5 | MP0009745_abnormal_behavioral_response | 3.44016270 |
6 | MP0002063_abnormal_learning/memory/cond | 3.43670416 |
7 | MP0005423_abnormal_somatic_nervous | 3.38861671 |
8 | MP0002064_seizures | 3.14677937 |
9 | MP0009046_muscle_twitch | 2.93123190 |
10 | MP0002572_abnormal_emotion/affect_behav | 2.82334681 |
11 | MP0001968_abnormal_touch/_nociception | 2.74365932 |
12 | MP0003136_yellow_coat_color | 2.67019855 |
13 | MP0001486_abnormal_startle_reflex | 2.49865168 |
14 | MP0002822_catalepsy | 2.47779429 |
15 | MP0002272_abnormal_nervous_system | 2.45393469 |
16 | MP0002734_abnormal_mechanical_nocicepti | 2.37150376 |
17 | MP0001501_abnormal_sleep_pattern | 2.30907920 |
18 | MP0001440_abnormal_grooming_behavior | 2.16214050 |
19 | MP0002736_abnormal_nociception_after | 2.10993712 |
20 | MP0002733_abnormal_thermal_nociception | 2.09569910 |
21 | MP0000778_abnormal_nervous_system | 2.09167063 |
22 | MP0000566_synostosis | 2.07448831 |
23 | MP0003329_amyloid_beta_deposits | 2.06806007 |
24 | MP0004858_abnormal_nervous_system | 2.02354186 |
25 | MP0002735_abnormal_chemical_nociception | 2.00774568 |
26 | MP0009780_abnormal_chondrocyte_physiolo | 1.95240346 |
27 | MP0002638_abnormal_pupillary_reflex | 1.93321669 |
28 | MP0002184_abnormal_innervation | 1.91480164 |
29 | MP0001970_abnormal_pain_threshold | 1.90862802 |
30 | MP0002067_abnormal_sensory_capabilities | 1.85926014 |
31 | MP0008569_lethality_at_weaning | 1.83210542 |
32 | MP0006276_abnormal_autonomic_nervous | 1.82671126 |
33 | MP0002909_abnormal_adrenal_gland | 1.81227787 |
34 | MP0004811_abnormal_neuron_physiology | 1.80398121 |
35 | MP0002557_abnormal_social/conspecific_i | 1.75131129 |
36 | MP0004133_heterotaxia | 1.72507873 |
37 | MP0002102_abnormal_ear_morphology | 1.67123296 |
38 | MP0004924_abnormal_behavior | 1.65757533 |
39 | MP0005386_behavior/neurological_phenoty | 1.65757533 |
40 | MP0005646_abnormal_pituitary_gland | 1.64128371 |
41 | MP0000955_abnormal_spinal_cord | 1.63859848 |
42 | MP0005645_abnormal_hypothalamus_physiol | 1.58824507 |
43 | MP0001984_abnormal_olfaction | 1.55865840 |
44 | MP0001485_abnormal_pinna_reflex | 1.48749510 |
45 | MP0004885_abnormal_endolymph | 1.48355594 |
46 | MP0002882_abnormal_neuron_morphology | 1.45383379 |
47 | MP0003787_abnormal_imprinting | 1.44903772 |
48 | MP0002066_abnormal_motor_capabilities/c | 1.41676926 |
49 | MP0003122_maternal_imprinting | 1.41074819 |
50 | MP0005377_hearing/vestibular/ear_phenot | 1.34855571 |
51 | MP0003878_abnormal_ear_physiology | 1.34855571 |
52 | MP0001502_abnormal_circadian_rhythm | 1.33541367 |
53 | MP0003879_abnormal_hair_cell | 1.32383618 |
54 | MP0001529_abnormal_vocalization | 1.31306237 |
55 | MP0003121_genomic_imprinting | 1.28725262 |
56 | MP0003633_abnormal_nervous_system | 1.26287864 |
57 | MP0002928_abnormal_bile_duct | 1.26008224 |
58 | MP0003938_abnormal_ear_development | 1.23878504 |
59 | MP0001905_abnormal_dopamine_level | 1.23556072 |
60 | MP0004142_abnormal_muscle_tone | 1.23434953 |
61 | MP0003011_delayed_dark_adaptation | 1.19023763 |
62 | MP0002152_abnormal_brain_morphology | 1.18254481 |
63 | MP0003631_nervous_system_phenotype | 1.12889642 |
64 | MP0003283_abnormal_digestive_organ | 1.05192781 |
65 | MP0000751_myopathy | 1.04947420 |
66 | MP0004145_abnormal_muscle_electrophysio | 1.04134195 |
67 | MP0002249_abnormal_larynx_morphology | 1.02423534 |
68 | MP0002751_abnormal_autonomic_nervous | 0.99220271 |
69 | MP0004147_increased_porphyrin_level | 0.96200373 |
70 | MP0002069_abnormal_eating/drinking_beha | 0.95339585 |
71 | MP0001188_hyperpigmentation | 0.94613952 |
72 | MP0000631_abnormal_neuroendocrine_gland | 0.93196898 |
73 | MP0000604_amyloidosis | 0.92036715 |
74 | MP0003075_altered_response_to | 0.91989907 |
75 | MP0003632_abnormal_nervous_system | 0.90737540 |
76 | MP0005253_abnormal_eye_physiology | 0.90587390 |
77 | MP0003634_abnormal_glial_cell | 0.88991208 |
78 | MP0006072_abnormal_retinal_apoptosis | 0.86706491 |
79 | MP0002229_neurodegeneration | 0.86200218 |
80 | MP0004085_abnormal_heartbeat | 0.85928943 |
81 | MP0008872_abnormal_physiological_respon | 0.85764862 |
82 | MP0001986_abnormal_taste_sensitivity | 0.85052925 |
83 | MP0008877_abnormal_DNA_methylation | 0.84916387 |
84 | MP0003890_abnormal_embryonic-extraembry | 0.84643449 |
85 | MP0002938_white_spotting | 0.84508125 |
86 | MP0003137_abnormal_impulse_conducting | 0.82325717 |
87 | MP0005535_abnormal_body_temperature | 0.81538328 |
88 | MP0010386_abnormal_urinary_bladder | 0.81316108 |
89 | MP0008961_abnormal_basal_metabolism | 0.81138239 |
90 | MP0003119_abnormal_digestive_system | 0.81042463 |
91 | MP0005551_abnormal_eye_electrophysiolog | 0.80887910 |
92 | MP0005499_abnormal_olfactory_system | 0.79859443 |
93 | MP0005394_taste/olfaction_phenotype | 0.79859443 |
94 | MP0000569_abnormal_digit_pigmentation | 0.79474621 |
95 | MP0008874_decreased_physiological_sensi | 0.79039061 |
96 | MP0005195_abnormal_posterior_eye | 0.78744066 |
97 | MP0001177_atelectasis | 0.78490608 |
98 | MP0003690_abnormal_glial_cell | 0.78248641 |
99 | MP0002752_abnormal_somatic_nervous | 0.77263330 |
100 | MP0001293_anophthalmia | 0.76917231 |
101 | MP0001963_abnormal_hearing_physiology | 0.75000518 |
102 | MP0000049_abnormal_middle_ear | 0.74753509 |
103 | MP0002837_dystrophic_cardiac_calcinosis | 0.74697853 |
104 | MP0010030_abnormal_orbit_morphology | 0.74529024 |
105 | MP0004742_abnormal_vestibular_system | 0.73435015 |
106 | MP0001346_abnormal_lacrimal_gland | 0.73101814 |
107 | MP0004215_abnormal_myocardial_fiber | 0.72925377 |
108 | MP0005248_abnormal_Harderian_gland | 0.70481012 |
109 | MP0005171_absent_coat_pigmentation | 0.69905698 |
110 | MP0004484_altered_response_of | 0.68888784 |
111 | MP0008995_early_reproductive_senescence | 0.68449661 |
112 | MP0000920_abnormal_myelination | 0.68037735 |
113 | MP0003942_abnormal_urinary_system | 0.67468352 |
114 | MP0001664_abnormal_digestion | 0.66448550 |
115 | MP0002653_abnormal_ependyma_morphology | 0.65993055 |
116 | MP0005623_abnormal_meninges_morphology | 0.65620099 |
117 | MP0002234_abnormal_pharynx_morphology | 0.65576490 |
118 | MP0003172_abnormal_lysosome_physiology | 0.65097596 |
119 | MP0000013_abnormal_adipose_tissue | 0.64864686 |
120 | MP0003861_abnormal_nervous_system | 0.64742391 |
121 | MP0002090_abnormal_vision | 0.64162032 |
122 | MP0004233_abnormal_muscle_weight | 0.63141857 |
123 | MP0005409_darkened_coat_color | 0.62261740 |
124 | MP0006292_abnormal_olfactory_placode | 0.58760858 |
125 | MP0004510_myositis | 0.56615992 |
126 | MP0005167_abnormal_blood-brain_barrier | 0.56174035 |
127 | MP0001943_abnormal_respiration | 0.56024589 |
128 | MP0005187_abnormal_penis_morphology | 0.55743038 |
129 | MP0010769_abnormal_survival | 0.53225513 |
130 | MP0000026_abnormal_inner_ear | 0.51479173 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.49334029 |
2 | Myokymia (HP:0002411) | 6.98821216 |
3 | Focal seizures (HP:0007359) | 5.80914336 |
4 | Visual hallucinations (HP:0002367) | 5.41814397 |
5 | Epileptic encephalopathy (HP:0200134) | 4.74034090 |
6 | Progressive cerebellar ataxia (HP:0002073) | 4.50589775 |
7 | Atonic seizures (HP:0010819) | 4.31110715 |
8 | Febrile seizures (HP:0002373) | 4.15374334 |
9 | Absence seizures (HP:0002121) | 4.06007864 |
10 | Action tremor (HP:0002345) | 4.04953810 |
11 | Supranuclear gaze palsy (HP:0000605) | 3.80746532 |
12 | Dialeptic seizures (HP:0011146) | 3.77114279 |
13 | Generalized tonic-clonic seizures (HP:0002069) | 3.73638841 |
14 | Broad-based gait (HP:0002136) | 3.55678467 |
15 | Abnormal eating behavior (HP:0100738) | 3.35476857 |
16 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.25414954 |
17 | Depression (HP:0000716) | 3.23162178 |
18 | True hermaphroditism (HP:0010459) | 3.22935878 |
19 | Mutism (HP:0002300) | 3.21019041 |
20 | Poor eye contact (HP:0000817) | 3.20524262 |
21 | Ankle clonus (HP:0011448) | 3.17452501 |
22 | Anxiety (HP:0000739) | 3.13630317 |
23 | Cerebral inclusion bodies (HP:0100314) | 3.12621948 |
24 | Hyperventilation (HP:0002883) | 3.11832237 |
25 | Dysdiadochokinesis (HP:0002075) | 3.08293533 |
26 | Dysmetria (HP:0001310) | 3.05615011 |
27 | Truncal ataxia (HP:0002078) | 3.02612989 |
28 | Neurofibrillary tangles (HP:0002185) | 3.01903720 |
29 | Gaze-evoked nystagmus (HP:0000640) | 3.01113203 |
30 | Amblyopia (HP:0000646) | 2.98993766 |
31 | Pancreatic fibrosis (HP:0100732) | 2.98152917 |
32 | Hemiparesis (HP:0001269) | 2.94835460 |
33 | Septo-optic dysplasia (HP:0100842) | 2.94424077 |
34 | Drooling (HP:0002307) | 2.92330897 |
35 | Excessive salivation (HP:0003781) | 2.92330897 |
36 | Abnormality of the lower motor neuron (HP:0002366) | 2.89838144 |
37 | Nephronophthisis (HP:0000090) | 2.89718499 |
38 | Abnormal social behavior (HP:0012433) | 2.89249659 |
39 | Impaired social interactions (HP:0000735) | 2.89249659 |
40 | Megalencephaly (HP:0001355) | 2.89099412 |
41 | Pancreatic cysts (HP:0001737) | 2.85869633 |
42 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.83254606 |
43 | Postural instability (HP:0002172) | 2.82051979 |
44 | Genetic anticipation (HP:0003743) | 2.81218474 |
45 | Molar tooth sign on MRI (HP:0002419) | 2.75347703 |
46 | Abnormality of midbrain morphology (HP:0002418) | 2.75347703 |
47 | Papilledema (HP:0001085) | 2.70835868 |
48 | Torticollis (HP:0000473) | 2.66778033 |
49 | Diplopia (HP:0000651) | 2.66178594 |
50 | Abnormality of binocular vision (HP:0011514) | 2.66178594 |
51 | Type II lissencephaly (HP:0007260) | 2.61372323 |
52 | Split foot (HP:0001839) | 2.60363546 |
53 | Abnormality of the labia minora (HP:0012880) | 2.59282965 |
54 | Hemiplegia (HP:0002301) | 2.57457685 |
55 | Stereotypic behavior (HP:0000733) | 2.54394803 |
56 | Impaired smooth pursuit (HP:0007772) | 2.53862543 |
57 | Urinary urgency (HP:0000012) | 2.53060920 |
58 | Focal dystonia (HP:0004373) | 2.51624213 |
59 | Spastic gait (HP:0002064) | 2.50205025 |
60 | Epileptiform EEG discharges (HP:0011182) | 2.48997674 |
61 | Progressive inability to walk (HP:0002505) | 2.48235894 |
62 | Intention tremor (HP:0002080) | 2.44627102 |
63 | Abnormal ciliary motility (HP:0012262) | 2.41327762 |
64 | Polyphagia (HP:0002591) | 2.41147341 |
65 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.40639414 |
66 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.40639414 |
67 | Rib fusion (HP:0000902) | 2.38611028 |
68 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.38246880 |
69 | Ventricular fibrillation (HP:0001663) | 2.37906634 |
70 | Scanning speech (HP:0002168) | 2.37315573 |
71 | EEG with generalized epileptiform discharges (HP:0011198) | 2.36837542 |
72 | Bradykinesia (HP:0002067) | 2.36233016 |
73 | Lissencephaly (HP:0001339) | 2.33687643 |
74 | Termporal pattern (HP:0011008) | 2.33397389 |
75 | Insidious onset (HP:0003587) | 2.33397389 |
76 | Optic nerve hypoplasia (HP:0000609) | 2.32754619 |
77 | Oligodactyly (hands) (HP:0001180) | 2.30207795 |
78 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.29641540 |
79 | Abnormality of the corticospinal tract (HP:0002492) | 2.28755208 |
80 | Amyotrophic lateral sclerosis (HP:0007354) | 2.28147466 |
81 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.27067708 |
82 | Chronic hepatic failure (HP:0100626) | 2.26880545 |
83 | Retinal dysplasia (HP:0007973) | 2.23162429 |
84 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.23145269 |
85 | Aplasia of the phalanges of the hand (HP:0009802) | 2.23145269 |
86 | Aplasia involving bones of the extremities (HP:0009825) | 2.23145269 |
87 | Hypsarrhythmia (HP:0002521) | 2.23045365 |
88 | Abnormality of the renal medulla (HP:0100957) | 2.22116877 |
89 | Cystic liver disease (HP:0006706) | 2.22013027 |
90 | Fetal akinesia sequence (HP:0001989) | 2.21863528 |
91 | Anophthalmia (HP:0000528) | 2.21371993 |
92 | Insomnia (HP:0100785) | 2.19981982 |
93 | Agitation (HP:0000713) | 2.19624976 |
94 | Status epilepticus (HP:0002133) | 2.18254943 |
95 | Craniofacial dystonia (HP:0012179) | 2.17329087 |
96 | Medial flaring of the eyebrow (HP:0010747) | 2.14638202 |
97 | Obstructive sleep apnea (HP:0002870) | 2.12122429 |
98 | Congenital stationary night blindness (HP:0007642) | 2.11484235 |
99 | Absent speech (HP:0001344) | 2.11118059 |
100 | Lower limb muscle weakness (HP:0007340) | 2.10175851 |
101 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.10174485 |
102 | Absent/shortened dynein arms (HP:0200106) | 2.10174485 |
103 | Pointed chin (HP:0000307) | 2.09841866 |
104 | Limb dystonia (HP:0002451) | 2.09295479 |
105 | Impaired vibratory sensation (HP:0002495) | 2.07906140 |
106 | Gait imbalance (HP:0002141) | 2.07258554 |
107 | Cutaneous finger syndactyly (HP:0010554) | 2.06196876 |
108 | Generalized myoclonic seizures (HP:0002123) | 2.05848157 |
109 | Annular pancreas (HP:0001734) | 2.02047261 |
110 | Abnormality of salivation (HP:0100755) | 1.98923554 |
111 | Incomplete penetrance (HP:0003829) | 1.98042224 |
112 | Decreased central vision (HP:0007663) | 1.98032365 |
113 | Polydipsia (HP:0001959) | 1.98012246 |
114 | Abnormal drinking behavior (HP:0030082) | 1.98012246 |
115 | Delusions (HP:0000746) | 1.97213291 |
116 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.97109519 |
117 | Inability to walk (HP:0002540) | 1.96441341 |
118 | Dysmetric saccades (HP:0000641) | 1.95398116 |
119 | Pachygyria (HP:0001302) | 1.94744401 |
120 | Anencephaly (HP:0002323) | 1.93821217 |
121 | Stomach cancer (HP:0012126) | 1.93773723 |
122 | Abnormal EKG (HP:0003115) | 1.93446161 |
123 | Morphological abnormality of the inner ear (HP:0011390) | 1.91817760 |
124 | Concave nail (HP:0001598) | 1.89876952 |
125 | Occipital encephalocele (HP:0002085) | 1.89730239 |
126 | Blue irides (HP:0000635) | 1.89394324 |
127 | Pheochromocytoma (HP:0002666) | 1.89046801 |
128 | Cerebellar dysplasia (HP:0007033) | 1.88598522 |
129 | Gait ataxia (HP:0002066) | 1.86092977 |
130 | Apathy (HP:0000741) | 1.84786727 |
131 | Postaxial hand polydactyly (HP:0001162) | 1.84704932 |
132 | Narrow forehead (HP:0000341) | 1.84591799 |
133 | Sleep apnea (HP:0010535) | 1.84366854 |
134 | Lower limb asymmetry (HP:0100559) | 1.83590012 |
135 | Absent septum pellucidum (HP:0001331) | 1.83229119 |
136 | Sclerocornea (HP:0000647) | 1.82755619 |
137 | Psychosis (HP:0000709) | 1.82128013 |
138 | Anosmia (HP:0000458) | 1.81475651 |
139 | Specific learning disability (HP:0001328) | 1.81394151 |
140 | Oligodactyly (HP:0012165) | 1.81347765 |
141 | Neuronal loss in central nervous system (HP:0002529) | 1.80792150 |
142 | Rapidly progressive (HP:0003678) | 1.78349956 |
143 | Failure to thrive in infancy (HP:0001531) | 1.76895709 |
144 | Spastic tetraplegia (HP:0002510) | 1.75514552 |
145 | Ulnar claw (HP:0001178) | 1.74847507 |
146 | Lower limb amyotrophy (HP:0007210) | 1.74036612 |
147 | Cutaneous syndactyly (HP:0012725) | 1.73999301 |
148 | Tubular atrophy (HP:0000092) | 1.73025557 |
149 | Rigidity (HP:0002063) | 1.71336139 |
150 | Thickened helices (HP:0000391) | 1.70203328 |
151 | Inappropriate behavior (HP:0000719) | 1.70138560 |
152 | Rhinitis (HP:0012384) | 1.69915473 |
153 | Hypoplasia of the corpus callosum (HP:0002079) | 1.67637622 |
154 | Increased corneal curvature (HP:0100692) | 1.67383498 |
155 | Keratoconus (HP:0000563) | 1.67383498 |
156 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.66690051 |
157 | Genital tract atresia (HP:0001827) | 1.66606714 |
158 | Narrow nasal bridge (HP:0000446) | 1.66090352 |
159 | Postaxial foot polydactyly (HP:0001830) | 1.64817349 |
160 | Hypoplasia of the brainstem (HP:0002365) | 1.63936240 |
161 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.63936240 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 4.82956779 |
2 | NTRK3 | 4.74504426 |
3 | MAP3K9 | 3.80725597 |
4 | MARK1 | 3.33742240 |
5 | MINK1 | 2.74015980 |
6 | MAP3K4 | 2.72537018 |
7 | PAK6 | 2.36069880 |
8 | MAPK15 | 2.27894332 |
9 | PRKD3 | 2.24924620 |
10 | MAP2K7 | 2.24618117 |
11 | KSR2 | 2.22629211 |
12 | NTRK2 | 2.20631496 |
13 | DAPK2 | 2.19741785 |
14 | FGFR2 | 1.99994076 |
15 | DYRK2 | 1.97817092 |
16 | KSR1 | 1.86342795 |
17 | RIPK4 | 1.84339019 |
18 | TNIK | 1.81548445 |
19 | CAMKK1 | 1.68211833 |
20 | MAP2K4 | 1.68004707 |
21 | MAP3K12 | 1.65754610 |
22 | NTRK1 | 1.59195984 |
23 | CDK5 | 1.57007909 |
24 | ARAF | 1.52732884 |
25 | WNK3 | 1.49599750 |
26 | PLK2 | 1.49329211 |
27 | PRPF4B | 1.48356439 |
28 | FRK | 1.48013261 |
29 | SIK2 | 1.46046946 |
30 | DAPK1 | 1.44225480 |
31 | CASK | 1.43354149 |
32 | MAPK13 | 1.39825885 |
33 | BMPR1B | 1.38485494 |
34 | WNK4 | 1.38398274 |
35 | GRK5 | 1.38307995 |
36 | MAP3K13 | 1.36454521 |
37 | PRKCG | 1.29631325 |
38 | PHKG1 | 1.26401756 |
39 | PHKG2 | 1.26401756 |
40 | PNCK | 1.26374081 |
41 | EPHB2 | 1.25269536 |
42 | EPHA3 | 1.25213210 |
43 | STK38 | 1.22197678 |
44 | TYRO3 | 1.21481625 |
45 | FES | 1.21171021 |
46 | UHMK1 | 1.12518692 |
47 | TAOK3 | 1.10380738 |
48 | TSSK6 | 1.06922433 |
49 | CAMK2A | 1.06909449 |
50 | CDK19 | 1.03121445 |
51 | LATS2 | 0.97770108 |
52 | ADRBK2 | 0.97570051 |
53 | PTK2B | 0.96630758 |
54 | RAF1 | 0.94854211 |
55 | CDK18 | 0.94371586 |
56 | CDK15 | 0.92678859 |
57 | CAMK1 | 0.92395665 |
58 | LMTK2 | 0.91981154 |
59 | CAMK2B | 0.90272581 |
60 | PAK3 | 0.89512345 |
61 | MAP3K2 | 0.89390324 |
62 | CDK14 | 0.88572675 |
63 | PRKCH | 0.82915155 |
64 | DYRK1A | 0.82394115 |
65 | STK39 | 0.81006592 |
66 | CDK11A | 0.80565138 |
67 | ERBB2 | 0.80025289 |
68 | SGK223 | 0.78188305 |
69 | SGK494 | 0.78188305 |
70 | MARK2 | 0.76513795 |
71 | STK11 | 0.76008476 |
72 | PKN1 | 0.75497132 |
73 | TAOK1 | 0.75247521 |
74 | DYRK1B | 0.75104798 |
75 | CAMKK2 | 0.74582507 |
76 | GRK1 | 0.73817472 |
77 | ALK | 0.71201279 |
78 | BMPR2 | 0.71148678 |
79 | TLK1 | 0.71036793 |
80 | NME1 | 0.68452225 |
81 | SGK1 | 0.66677392 |
82 | RET | 0.66284612 |
83 | MAP3K7 | 0.65166652 |
84 | FGR | 0.62529877 |
85 | PINK1 | 0.62185995 |
86 | PRKCZ | 0.61766359 |
87 | SGK2 | 0.59177419 |
88 | TXK | 0.57803455 |
89 | CSNK1G2 | 0.55899202 |
90 | MAP4K2 | 0.54873468 |
91 | PDK1 | 0.54240688 |
92 | RIPK1 | 0.54186461 |
93 | CSNK1G3 | 0.52075752 |
94 | TNK2 | 0.51886756 |
95 | SGK3 | 0.51053277 |
96 | PRKCE | 0.50553423 |
97 | GRK6 | 0.49735767 |
98 | CAMK2D | 0.49577935 |
99 | PDPK1 | 0.49079252 |
100 | OXSR1 | 0.48586142 |
101 | ROCK2 | 0.47637174 |
102 | RPS6KA3 | 0.47573715 |
103 | RPS6KA2 | 0.46799233 |
104 | FER | 0.46796751 |
105 | MAP3K1 | 0.46785358 |
106 | CSNK1G1 | 0.46563596 |
107 | PLK4 | 0.46500683 |
108 | MAPK10 | 0.46368137 |
109 | CDK3 | 0.45661244 |
110 | MAP2K2 | 0.44843321 |
111 | FYN | 0.44640353 |
112 | CAMK2G | 0.44587425 |
113 | INSRR | 0.44553398 |
114 | CDC42BPA | 0.44263899 |
115 | CAMK4 | 0.44216577 |
116 | PRKACA | 0.43272379 |
117 | ADRBK1 | 0.43128551 |
118 | WNK1 | 0.39123988 |
119 | PRKCQ | 0.37419877 |
120 | NUAK1 | 0.36757587 |
121 | IRAK2 | 0.36721789 |
122 | MAP2K1 | 0.36497051 |
123 | NEK1 | 0.36383555 |
124 | BRAF | 0.36231136 |
125 | CAMK1G | 0.35621753 |
126 | IRAK1 | 0.35056385 |
127 | MAPK12 | 0.34962875 |
128 | SIK3 | 0.34037862 |
129 | MAP3K6 | 0.33892453 |
130 | NEK6 | 0.33636765 |
131 | DYRK3 | 0.31965556 |
132 | DAPK3 | 0.31566851 |
133 | CSNK1D | 0.31554962 |
134 | PRKD2 | 0.31200713 |
135 | DDR2 | 0.30744212 |
136 | ZAK | 0.30561732 |
137 | PRKCB | 0.29760422 |
138 | PRKCI | 0.29692237 |
139 | PRKG1 | 0.29604439 |
140 | PRKCA | 0.28603699 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.88669785 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.03341709 |
3 | Long-term potentiation_Homo sapiens_hsa04720 | 2.77730994 |
4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.77033113 |
5 | GABAergic synapse_Homo sapiens_hsa04727 | 2.70927964 |
6 | Olfactory transduction_Homo sapiens_hsa04740 | 2.69725481 |
7 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.68037083 |
8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.64148086 |
9 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.47373667 |
10 | Morphine addiction_Homo sapiens_hsa05032 | 2.45296475 |
11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.26709413 |
12 | Salivary secretion_Homo sapiens_hsa04970 | 2.26547303 |
13 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.14499778 |
14 | Insulin secretion_Homo sapiens_hsa04911 | 1.99107469 |
15 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.94300053 |
16 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.88998589 |
17 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.86447592 |
18 | Taste transduction_Homo sapiens_hsa04742 | 1.84494435 |
19 | Long-term depression_Homo sapiens_hsa04730 | 1.73825647 |
20 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.72378353 |
21 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.68077791 |
22 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.67242234 |
23 | Renin secretion_Homo sapiens_hsa04924 | 1.66969359 |
24 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.66335256 |
25 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.64164071 |
26 | Cocaine addiction_Homo sapiens_hsa05030 | 1.60221840 |
27 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.56250674 |
28 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.47872395 |
29 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.47795838 |
30 | Gap junction_Homo sapiens_hsa04540 | 1.40955106 |
31 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.37802709 |
32 | Axon guidance_Homo sapiens_hsa04360 | 1.33891039 |
33 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.31403331 |
34 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.29252976 |
35 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.28797246 |
36 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.27704521 |
37 | Glioma_Homo sapiens_hsa05214 | 1.19390194 |
38 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.16876882 |
39 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.16373628 |
40 | Melanogenesis_Homo sapiens_hsa04916 | 1.15173467 |
41 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.13350449 |
42 | Parkinsons disease_Homo sapiens_hsa05012 | 1.13141556 |
43 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.12483011 |
44 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.12297084 |
45 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.10845655 |
46 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.08039425 |
47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06576952 |
48 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.06442459 |
49 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.02800533 |
50 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.94716533 |
51 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.93710492 |
52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.91406669 |
53 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.91310341 |
54 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.90181819 |
55 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.89453801 |
56 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.88521053 |
57 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.88193329 |
58 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.86513708 |
59 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.84451578 |
60 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.83239797 |
61 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.82686373 |
62 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.82021517 |
63 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.79451058 |
64 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.77759989 |
65 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.77420442 |
66 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.77242913 |
67 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.76234254 |
68 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.75795549 |
69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75621777 |
70 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.72582512 |
71 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.70396440 |
72 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.68534180 |
73 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.68275158 |
74 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.68022795 |
75 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.67850588 |
76 | Huntingtons disease_Homo sapiens_hsa05016 | 0.66958365 |
77 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.65905319 |
78 | Phototransduction_Homo sapiens_hsa04744 | 0.63636611 |
79 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.63138668 |
80 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.63097984 |
81 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.60881078 |
82 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.59822731 |
83 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.59597671 |
84 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56372710 |
85 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.55484227 |
86 | Bile secretion_Homo sapiens_hsa04976 | 0.54971126 |
87 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.54515953 |
88 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.53713149 |
89 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.53253483 |
90 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.51872844 |
91 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.51471709 |
92 | Prion diseases_Homo sapiens_hsa05020 | 0.49543851 |
93 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.49542140 |
94 | Endometrial cancer_Homo sapiens_hsa05213 | 0.49286663 |
95 | Alcoholism_Homo sapiens_hsa05034 | 0.48387480 |
96 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.47555583 |
97 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.47161908 |
98 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.44818031 |
99 | Endocytosis_Homo sapiens_hsa04144 | 0.44150530 |
100 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.44110744 |
101 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.43617646 |
102 | Alzheimers disease_Homo sapiens_hsa05010 | 0.43334926 |
103 | Circadian rhythm_Homo sapiens_hsa04710 | 0.41495450 |
104 | ABC transporters_Homo sapiens_hsa02010 | 0.41402535 |
105 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.40550543 |
106 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.40136003 |
107 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.38491895 |
108 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.38019733 |
109 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.37983729 |
110 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.36635056 |
111 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.36553947 |
112 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.36475330 |
113 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.36126408 |
114 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.35221184 |
115 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.33863266 |
116 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.31241164 |
117 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.30617076 |
118 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.29632062 |
119 | Colorectal cancer_Homo sapiens_hsa05210 | 0.28043478 |
120 | Sulfur relay system_Homo sapiens_hsa04122 | 0.27840775 |
121 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.25851723 |
122 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.24807187 |
123 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.23331745 |
124 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.22401877 |
125 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.21711047 |