LSM10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.61763891
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.32489599
3DNA deamination (GO:0045006)5.09364801
4chaperone-mediated protein transport (GO:0072321)4.92055509
5mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.77129771
6ATP synthesis coupled proton transport (GO:0015986)4.68911763
7energy coupled proton transport, down electrochemical gradient (GO:0015985)4.68911763
8protein complex biogenesis (GO:0070271)4.54090765
9respiratory electron transport chain (GO:0022904)4.50839355
10electron transport chain (GO:0022900)4.39909964
11mitochondrial respiratory chain complex assembly (GO:0033108)4.27375985
12proteasome assembly (GO:0043248)4.24215532
13establishment of protein localization to mitochondrial membrane (GO:0090151)4.20587800
14protein targeting to mitochondrion (GO:0006626)4.07648872
15viral transcription (GO:0019083)4.01226950
16ribosomal small subunit biogenesis (GO:0042274)3.90426602
17translational termination (GO:0006415)3.88124847
18establishment of protein localization to mitochondrion (GO:0072655)3.74261495
19telomere maintenance via semi-conservative replication (GO:0032201)3.73565521
20maturation of SSU-rRNA (GO:0030490)3.73501950
21regulation of mitochondrial translation (GO:0070129)3.67556927
22SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.67099625
23protein localization to mitochondrion (GO:0070585)3.62954278
24pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.59730085
25cotranslational protein targeting to membrane (GO:0006613)3.59699363
26oxidative phosphorylation (GO:0006119)3.57053344
27protein targeting to ER (GO:0045047)3.55242498
28translational elongation (GO:0006414)3.53514296
29telomere maintenance via recombination (GO:0000722)3.48692113
30protein maturation by protein folding (GO:0022417)3.45471403
31negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.42706942
32protein localization to endoplasmic reticulum (GO:0070972)3.42357233
33antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.39421313
34GTP biosynthetic process (GO:0006183)3.38059136
35platelet dense granule organization (GO:0060155)3.37888331
36DNA strand elongation involved in DNA replication (GO:0006271)3.37583880
37establishment of protein localization to endoplasmic reticulum (GO:0072599)3.32745958
38fatty acid elongation (GO:0030497)3.31090194
39DNA strand elongation (GO:0022616)3.30303088
407-methylguanosine mRNA capping (GO:0006370)3.29891083
41antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.28748184
42transcription elongation from RNA polymerase III promoter (GO:0006385)3.28355203
43termination of RNA polymerase III transcription (GO:0006386)3.28355203
447-methylguanosine RNA capping (GO:0009452)3.27898415
45RNA capping (GO:0036260)3.27898415
46DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.27315600
47pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.25579851
48tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.25033052
49RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.25033052
50base-excision repair, AP site formation (GO:0006285)3.22794290
51exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.22468996
52ribosomal large subunit biogenesis (GO:0042273)3.21669817
53signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.19973403
54intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.19973403
55ubiquinone biosynthetic process (GO:0006744)3.19237823
56positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.19221477
57regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.19163461
58formation of translation preinitiation complex (GO:0001731)3.18490946
59guanosine-containing compound biosynthetic process (GO:1901070)3.17564976
60viral life cycle (GO:0019058)3.17157973
61signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.16655726
62signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.16655726
63signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.16655726
64deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.15854649
65deoxyribonucleotide catabolic process (GO:0009264)3.15426275
66nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.14663544
67translational initiation (GO:0006413)3.12151385
68translation (GO:0006412)3.09533846
69negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.09193600
70negative regulation of ligase activity (GO:0051352)3.09193600
71peptidyl-histidine modification (GO:0018202)3.07965844
72deoxyribose phosphate catabolic process (GO:0046386)3.07647654
73anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.05686640
74nucleotide-excision repair, DNA gap filling (GO:0006297)3.04523898
75response to interferon-beta (GO:0035456)3.03635585
76signal transduction involved in DNA integrity checkpoint (GO:0072401)3.02796857
77signal transduction involved in DNA damage checkpoint (GO:0072422)3.02796857
78regulation of cellular amine metabolic process (GO:0033238)3.01558093
79ribonucleoprotein complex biogenesis (GO:0022613)3.01185675
80maturation of 5.8S rRNA (GO:0000460)3.00615940
81DNA replication initiation (GO:0006270)3.00334330
82telomere maintenance via telomere lengthening (GO:0010833)3.00328541
83purine-containing compound salvage (GO:0043101)3.00139013
84signal transduction involved in cell cycle checkpoint (GO:0072395)3.00027354
85mitochondrial transport (GO:0006839)2.99614284
86nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.99472899
87purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.98980360
88purine nucleoside triphosphate biosynthetic process (GO:0009145)2.98687892
89CENP-A containing nucleosome assembly (GO:0034080)2.98057461
90GMP metabolic process (GO:0046037)2.97284077
91L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.97153593
92pyrimidine nucleotide catabolic process (GO:0006244)2.95864558
93mitotic recombination (GO:0006312)2.95801524
94regulation of ubiquitin-protein transferase activity (GO:0051438)2.94977944
95regulation of cellular amino acid metabolic process (GO:0006521)2.94082896
96cellular protein complex disassembly (GO:0043624)2.93950057
97ubiquinone metabolic process (GO:0006743)2.93802174
98pseudouridine synthesis (GO:0001522)2.91182272
99nucleobase biosynthetic process (GO:0046112)2.91165072
100rRNA modification (GO:0000154)2.90192839
101transcription-coupled nucleotide-excision repair (GO:0006283)2.90007407
102purine nucleobase biosynthetic process (GO:0009113)2.88715604
103ATP biosynthetic process (GO:0006754)2.86639694
104UTP biosynthetic process (GO:0006228)2.85933487
105regulation of ligase activity (GO:0051340)2.84934251
106chromatin remodeling at centromere (GO:0031055)2.84447590
107autophagic vacuole fusion (GO:0000046)2.83676173
108protein deneddylation (GO:0000338)2.82864600
109purine deoxyribonucleotide catabolic process (GO:0009155)2.82317641
110respiratory chain complex IV assembly (GO:0008535)2.81585436
111spliceosomal snRNP assembly (GO:0000387)2.81190901
112hydrogen ion transmembrane transport (GO:1902600)2.81042607
1132-deoxyribonucleotide biosynthetic process (GO:0009265)2.80790135
114deoxyribose phosphate biosynthetic process (GO:0046385)2.80790135
115aerobic respiration (GO:0009060)2.78706706
116DNA replication checkpoint (GO:0000076)2.78607392
117DNA damage response, detection of DNA damage (GO:0042769)2.76598497
118establishment of integrated proviral latency (GO:0075713)2.76589534
119viral mRNA export from host cell nucleus (GO:0046784)2.74497829
120purine nucleotide salvage (GO:0032261)2.74425921
1212-deoxyribonucleotide metabolic process (GO:0009394)2.73567934
122antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.73258683
123pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.73231704
124positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.72366884
125metallo-sulfur cluster assembly (GO:0031163)2.71153574
126iron-sulfur cluster assembly (GO:0016226)2.71153574
127cellular component biogenesis (GO:0044085)2.69862741
128rRNA processing (GO:0006364)2.68698412
129DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.67770986
130positive regulation of ligase activity (GO:0051351)2.65315957
131mitochondrial respiratory chain complex I assembly (GO:0032981)2.64200687
132NADH dehydrogenase complex assembly (GO:0010257)2.64200687
133mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.64200687
134regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.63551256
135transcription from RNA polymerase I promoter (GO:0006360)2.63109063
136cullin deneddylation (GO:0010388)2.62235533
137DNA catabolic process, exonucleolytic (GO:0000738)2.61854462
138neutrophil activation involved in immune response (GO:0002283)2.60421049
139cytochrome complex assembly (GO:0017004)2.60289752
140protein neddylation (GO:0045116)2.59212988
141ribosome biogenesis (GO:0042254)2.58962686
142positive regulation of cell cycle arrest (GO:0071158)2.56409506
143transcription elongation from RNA polymerase II promoter (GO:0006368)2.56169464
144deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.55676198
145termination of RNA polymerase I transcription (GO:0006363)2.55533950
146kinetochore assembly (GO:0051382)2.55499080
147transcription elongation from RNA polymerase I promoter (GO:0006362)2.54897237
148rRNA metabolic process (GO:0016072)2.54686760
149nuclear-transcribed mRNA catabolic process (GO:0000956)2.54568445

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.50621962
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.02795902
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.86088013
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.54920876
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.50285585
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.45387928
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.43418420
8ELF1_17652178_ChIP-ChIP_JURKAT_Human3.01026916
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.97001376
10* ETS1_20019798_ChIP-Seq_JURKAT_Human2.86387231
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.81121657
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.69962754
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.66036141
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.62822328
15SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.61211650
16* VDR_23849224_ChIP-Seq_CD4+_Human2.50420526
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.49393084
18SRF_21415370_ChIP-Seq_HL-1_Mouse2.48455235
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.43958029
20BP1_19119308_ChIP-ChIP_Hs578T_Human2.43308880
21IRF8_21731497_ChIP-ChIP_J774_Mouse2.36001346
22MYC_19030024_ChIP-ChIP_MESCs_Mouse2.34390100
23FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.32779330
24IRF8_22096565_ChIP-ChIP_GC-B_Human2.31614586
25IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.30449556
26E2F4_17652178_ChIP-ChIP_JURKAT_Human2.28946471
27FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.23975405
28HOXB4_20404135_ChIP-ChIP_EML_Mouse2.15435472
29E2F1_18555785_ChIP-Seq_MESCs_Mouse2.13827060
30MYC_19079543_ChIP-ChIP_MESCs_Mouse2.12466563
31FOXP3_21729870_ChIP-Seq_TREG_Human2.12263670
32XRN2_22483619_ChIP-Seq_HELA_Human2.10713806
33SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.10226435
34NELFA_20434984_ChIP-Seq_ESCs_Mouse2.08592338
35DCP1A_22483619_ChIP-Seq_HELA_Human2.06306728
36ELK1_19687146_ChIP-ChIP_HELA_Human2.00047606
37TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.96431379
38* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.96076555
39PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.92687079
40* GABP_19822575_ChIP-Seq_HepG2_Human1.90909524
41* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.84945539
42PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.83733710
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.78562872
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.73001413
45* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.67494721
46* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.64925869
47TTF2_22483619_ChIP-Seq_HELA_Human1.63922234
48SPI1_23547873_ChIP-Seq_NB4_Human1.62489683
49* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.57746005
50MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.54604463
51MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.54571665
52CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.53782329
53MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.51470160
54FOXM1_23109430_ChIP-Seq_U2OS_Human1.46666151
55YY1_21170310_ChIP-Seq_MESCs_Mouse1.44498669
56STAT4_19710469_ChIP-ChIP_TH1__Mouse1.42432091
57NANOG_18555785_ChIP-Seq_MESCs_Mouse1.41843343
58ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.38747324
59* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.37726587
60RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.33782983
61MYCN_18555785_ChIP-Seq_MESCs_Mouse1.32471914
62MYC_18940864_ChIP-ChIP_HL60_Human1.26610088
63ELK1_22589737_ChIP-Seq_MCF10A_Human1.24911048
64RBPJ_22232070_ChIP-Seq_NCS_Mouse1.24756577
65ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.23782394
66MYB_21317192_ChIP-Seq_ERMYB_Mouse1.23268082
67MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.22988704
68CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.21854739
69E2F1_21310950_ChIP-Seq_MCF-7_Human1.20009500
70CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.17512857
71GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.16867171
72* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.15709716
73MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.15477938
74IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.14906415
75BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12811444
76AR_21909140_ChIP-Seq_LNCAP_Human1.12222694
77TFEB_21752829_ChIP-Seq_HELA_Human1.10135352
78ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09970422
79YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.09865858
80ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08846449
81CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06415390
82PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.06395889
83YY1_22570637_ChIP-Seq_MALME-3M_Human1.06038914
84BCL6_27268052_Chip-Seq_Bcells_Human1.04407391
85* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03595366
86CTCF_18555785_ChIP-Seq_MESCs_Mouse1.02043703
87CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.99800822
88TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.99790794
89EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.98606553
90ELF1_20517297_ChIP-Seq_JURKAT_Human0.98377328
91HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.97448203
92SCL_19346495_ChIP-Seq_HPC-7_Human0.95522821
93NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.94532620
94* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93646072
95CIITA_25753668_ChIP-Seq_RAJI_Human0.93093086
96POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.92533757
97LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.92228674
98RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.91701344
99KDM5A_27292631_Chip-Seq_BREAST_Human0.91474196
100CTCF_26484167_Chip-Seq_Bcells_Mouse0.90283445
101STAT3_1855785_ChIP-Seq_MESCs_Mouse0.90218876
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.90011550
103CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.89915657
104GATA2_22383799_ChIP-Seq_G1ME_Mouse0.89914605
105MYB_26560356_Chip-Seq_TH2_Human0.89432542
106LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.89186365
107GATA1_22383799_ChIP-Seq_G1ME_Mouse0.85796082
108TBX5_21415370_ChIP-Seq_HL-1_Mouse0.85222948
109PU.1_20513432_ChIP-Seq_Bcells_Mouse0.85029693
110FOXP1_21924763_ChIP-Seq_HESCs_Human0.84290055
111IRF8_27001747_Chip-Seq_BMDM_Mouse0.83740842
112PADI4_21655091_ChIP-ChIP_MCF-7_Human0.82518456
113HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.82225441
114HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.81447188
115STAT1_20625510_ChIP-Seq_HELA_Human0.80972201
116SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.80969020
117PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.80659864
118TP53_22573176_ChIP-Seq_HFKS_Human0.78342043

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching3.47699925
2MP0001835_abnormal_antigen_presentation3.46044903
3MP0009785_altered_susceptibility_to3.06792396
4MP0005671_abnormal_response_to2.69628415
5MP0008058_abnormal_DNA_repair2.67426225
6MP0003186_abnormal_redox_activity2.63370840
7MP0004957_abnormal_blastocyst_morpholog2.59975282
8MP0003077_abnormal_cell_cycle2.54502522
9MP0010094_abnormal_chromosome_stability2.53650707
10MP0002148_abnormal_hypersensitivity_rea2.52531309
11MP0000685_abnormal_immune_system2.46829350
12MP0003646_muscle_fatigue2.30029279
13MP0008007_abnormal_cellular_replicative2.28355306
14MP0008260_abnormal_autophagy2.23771575
15MP0005025_abnormal_response_to2.19574704
16MP0006082_CNS_inflammation2.18515350
17MP0003724_increased_susceptibility_to2.16063510
18MP0003436_decreased_susceptibility_to2.09533162
19MP0002132_abnormal_respiratory_system2.08126855
20MP0008057_abnormal_DNA_replication2.07734604
21MP0005000_abnormal_immune_tolerance2.06613863
22MP0001853_heart_inflammation2.05894604
23MP0003763_abnormal_thymus_physiology2.05021554
24MP0003806_abnormal_nucleotide_metabolis1.98459610
25MP0003111_abnormal_nucleus_morphology1.96658552
26MP0001529_abnormal_vocalization1.93764917
27MP0002396_abnormal_hematopoietic_system1.93649634
28MP0001800_abnormal_humoral_immune1.90352164
29MP0002452_abnormal_antigen_presenting1.89577311
30MP0002419_abnormal_innate_immunity1.88876043
31MP0009333_abnormal_splenocyte_physiolog1.86168164
32MP0002723_abnormal_immune_serum1.85247026
33MP0001819_abnormal_immune_cell1.83754596
34MP0002420_abnormal_adaptive_immunity1.83321698
35MP0002277_abnormal_respiratory_mucosa1.80027845
36MP0002837_dystrophic_cardiac_calcinosis1.77265218
37MP0002405_respiratory_system_inflammati1.75745456
38MP0002398_abnormal_bone_marrow1.74828554
39MP0009697_abnormal_copulation1.68499621
40MP0001790_abnormal_immune_system1.66129632
41MP0005387_immune_system_phenotype1.66129632
42MP0003718_maternal_effect1.63518354
43MP0003786_premature_aging1.63000131
44MP0001986_abnormal_taste_sensitivity1.62077082
45MP0001545_abnormal_hematopoietic_system1.57174988
46MP0005397_hematopoietic_system_phenotyp1.57174988
47MP0000689_abnormal_spleen_morphology1.56724229
48MP0000716_abnormal_immune_system1.55483451
49MP0002138_abnormal_hepatobiliary_system1.48870027
50MP0000343_altered_response_to1.48515383
51MP0000858_altered_metastatic_potential1.48399933
52MP0003011_delayed_dark_adaptation1.48013269
53MP0002722_abnormal_immune_system1.46178215
54MP0002429_abnormal_blood_cell1.45077753
55MP0006036_abnormal_mitochondrial_physio1.44202605
56MP0006054_spinal_hemorrhage1.43298345
57MP0009379_abnormal_foot_pigmentation1.41800430
58MP0005464_abnormal_platelet_physiology1.40297655
59MP0001764_abnormal_homeostasis1.37683803
60MP0002019_abnormal_tumor_incidence1.36506538
61MP0000490_abnormal_crypts_of1.36005896
62MP0002006_tumorigenesis1.33877649
63MP0008932_abnormal_embryonic_tissue1.33631967
64MP0004808_abnormal_hematopoietic_stem1.28863338
65MP0000372_irregular_coat_pigmentation1.27978211
66MP0000750_abnormal_muscle_regeneration1.26756638
67MP0003195_calcinosis1.26316665
68MP0001845_abnormal_inflammatory_respons1.26236485
69MP0008469_abnormal_protein_level1.25889064
70MP0005310_abnormal_salivary_gland1.24775436
71MP0000313_abnormal_cell_death1.22586289
72MP0004142_abnormal_muscle_tone1.18789738
73MP0001727_abnormal_embryo_implantation1.18378706
74MP0002736_abnormal_nociception_after1.18120922
75MP0006292_abnormal_olfactory_placode1.17028636
76MP0001873_stomach_inflammation1.07323741
77MP0004145_abnormal_muscle_electrophysio1.06978239
78MP0002166_altered_tumor_susceptibility1.06284799
79MP0000703_abnormal_thymus_morphology1.06140303
80MP0003656_abnormal_erythrocyte_physiolo1.03089855
81MP0001119_abnormal_female_reproductive1.02929910
82MP0010155_abnormal_intestine_physiology1.02824183
83MP0006035_abnormal_mitochondrial_morpho1.02351973
84MP0002163_abnormal_gland_morphology1.01788447
85MP0005332_abnormal_amino_acid1.00306915
86MP0001188_hyperpigmentation0.98709061
87MP0005075_abnormal_melanosome_morpholog0.98519894
88MP0000465_gastrointestinal_hemorrhage0.98437945
89MP0005379_endocrine/exocrine_gland_phen0.97826611
90MP0002095_abnormal_skin_pigmentation0.97434981
91MP0001348_abnormal_lacrimal_gland0.95748906
92MP0005166_decreased_susceptibility_to0.95612240
93MP0008873_increased_physiological_sensi0.94124642
94MP0008877_abnormal_DNA_methylation0.92692271
95MP0005636_abnormal_mineral_homeostasis0.88118373
96MP0005266_abnormal_metabolism0.88056267
97MP0005408_hypopigmentation0.87250190
98MP0005319_abnormal_enzyme/_coenzyme0.86899983
99MP0001533_abnormal_skeleton_physiology0.85527285
100MP0000749_muscle_degeneration0.83962637
101MP0004782_abnormal_surfactant_physiolog0.83394033
102MP0001968_abnormal_touch/_nociception0.83011814
103MP0000350_abnormal_cell_proliferation0.82851358
104MP0003448_altered_tumor_morphology0.82780036
105MP0005645_abnormal_hypothalamus_physiol0.78604499
106MP0002090_abnormal_vision0.75965068
107MP0009840_abnormal_foam_cell0.75434726
108MP0005376_homeostasis/metabolism_phenot0.75412330
109MP0005451_abnormal_body_composition0.73710675
110MP0008872_abnormal_physiological_respon0.73274965
111MP0006072_abnormal_retinal_apoptosis0.72410318
112MP0005058_abnormal_lysosome_morphology0.72267769
113MP0000358_abnormal_cell_content/0.72048263
114MP0005410_abnormal_fertilization0.71672922
115MP0001851_eye_inflammation0.71544993
116MP0009764_decreased_sensitivity_to0.71460377
117MP0005551_abnormal_eye_electrophysiolog0.71416929
118MP0002933_joint_inflammation0.71320858
119MP0002332_abnormal_exercise_endurance0.71218796
120MP0001905_abnormal_dopamine_level0.71128367
121MP0005670_abnormal_white_adipose0.71095293
122MP0005389_reproductive_system_phenotype0.71026716
123MP0005584_abnormal_enzyme/coenzyme_acti0.70905589
124MP0003787_abnormal_imprinting0.70899393
125MP0003136_yellow_coat_color0.70639354
126MP0002653_abnormal_ependyma_morphology0.70638854
127MP0002102_abnormal_ear_morphology0.70360430
128MP0009763_increased_sensitivity_to0.70120514
129MP0008789_abnormal_olfactory_epithelium0.69850285
130MP0004947_skin_inflammation0.67781211
131MP0004147_increased_porphyrin_level0.67729973
132MP0005084_abnormal_gallbladder_morpholo0.66710331
133MP0002210_abnormal_sex_determination0.65857946
134MP0001730_embryonic_growth_arrest0.64570179

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.09288335
2Abnormal number of erythroid precursors (HP:0012131)4.08897404
3Aplastic anemia (HP:0001915)3.93533992
4Cerebral edema (HP:0002181)3.69486073
5Reticulocytopenia (HP:0001896)3.68595463
6Recurrent abscess formation (HP:0002722)3.63396531
7Birth length less than 3rd percentile (HP:0003561)3.55614268
8Acute necrotizing encephalopathy (HP:0006965)3.33056235
9Mitochondrial inheritance (HP:0001427)3.29328762
10Hepatocellular necrosis (HP:0001404)3.20066646
11Type I transferrin isoform profile (HP:0003642)3.19445759
12Recurrent bacterial skin infections (HP:0005406)3.17198573
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.05464032
14Decreased activity of mitochondrial respiratory chain (HP:0008972)3.05464032
15Abnormal mitochondria in muscle tissue (HP:0008316)3.05220079
16Hepatic necrosis (HP:0002605)3.04188722
17Increased CSF lactate (HP:0002490)2.98547150
18Increased hepatocellular lipid droplets (HP:0006565)2.96558208
19Myositis (HP:0100614)2.94500307
20Aplasia/Hypoplasia of the sacrum (HP:0008517)2.91106370
213-Methylglutaconic aciduria (HP:0003535)2.88639325
22Exertional dyspnea (HP:0002875)2.83416465
23Thrombocytosis (HP:0001894)2.81467525
24Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.75296836
25Lipid accumulation in hepatocytes (HP:0006561)2.74872333
26Elevated erythrocyte sedimentation rate (HP:0003565)2.74325607
27Muscle fiber atrophy (HP:0100295)2.69866028
28Renal Fanconi syndrome (HP:0001994)2.69484804
29Type 2 muscle fiber atrophy (HP:0003554)2.69193342
30Optic disc pallor (HP:0000543)2.63738386
31Poor head control (HP:0002421)2.63101222
32Progressive macrocephaly (HP:0004481)2.61531408
33Acute encephalopathy (HP:0006846)2.57764022
34Increased serum lactate (HP:0002151)2.56815932
35Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.56307324
36Cerebral hypomyelination (HP:0006808)2.54639323
37Microretrognathia (HP:0000308)2.52966013
38Oral leukoplakia (HP:0002745)2.52494044
39Breast hypoplasia (HP:0003187)2.51970231
40Macrocytic anemia (HP:0001972)2.51938725
41Reduced antithrombin III activity (HP:0001976)2.51437033
42Emotional lability (HP:0000712)2.49429181
43Pallor (HP:0000980)2.46722869
44Stomatitis (HP:0010280)2.44940363
45Pancytopenia (HP:0001876)2.44130532
46CNS demyelination (HP:0007305)2.42897639
47Abnormality of the heme biosynthetic pathway (HP:0010472)2.41938421
48Abnormality of macrophages (HP:0004311)2.41485194
49Lethargy (HP:0001254)2.40347678
50Decreased electroretinogram (ERG) amplitude (HP:0000654)2.40096037
51Retrobulbar optic neuritis (HP:0100654)2.36977043
52Optic neuritis (HP:0100653)2.36977043
53IgM deficiency (HP:0002850)2.36494559
54Eczematoid dermatitis (HP:0000976)2.35182457
55Leukodystrophy (HP:0002415)2.31356669
56Rough bone trabeculation (HP:0100670)2.30950152
57Petechiae (HP:0000967)2.30517201
58Abnormal protein glycosylation (HP:0012346)2.29715841
59Abnormal glycosylation (HP:0012345)2.29715841
60Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.29715841
61Abnormal protein N-linked glycosylation (HP:0012347)2.29715841
62Microvesicular hepatic steatosis (HP:0001414)2.24823985
63Increased serum pyruvate (HP:0003542)2.24467913
64Abnormality of glycolysis (HP:0004366)2.24467913
65Vacuolated lymphocytes (HP:0001922)2.24375013
66Abnormality of the anterior horn cell (HP:0006802)2.24190761
67Degeneration of anterior horn cells (HP:0002398)2.24190761
68Orchitis (HP:0100796)2.23970078
69Pulmonary fibrosis (HP:0002206)2.22467460
70Increased intramyocellular lipid droplets (HP:0012240)2.22307884
71Respiratory difficulties (HP:0002880)2.22080080
72Progressive microcephaly (HP:0000253)2.21529681
73Autoimmune thrombocytopenia (HP:0001973)2.19331176
74Premature graying of hair (HP:0002216)2.18259133
75Abnormality of alanine metabolism (HP:0010916)2.17593684
76Hyperalaninemia (HP:0003348)2.17593684
77Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.17593684
78Generalized aminoaciduria (HP:0002909)2.16345989
79Lactic acidosis (HP:0003128)2.15138500
80Bone marrow hypocellularity (HP:0005528)2.14458985
81Nasal polyposis (HP:0100582)2.13307213
82Exercise intolerance (HP:0003546)2.11826037
83Abnormal pupillary function (HP:0007686)2.10872596
84Pancreatic cysts (HP:0001737)2.10342818
85Patellar aplasia (HP:0006443)2.10156134
86Mediastinal lymphadenopathy (HP:0100721)2.09636499
87Recurrent gram-negative bacterial infections (HP:0005420)2.07130246
88Increased IgM level (HP:0003496)2.05522409
89Abnormality of T cell number (HP:0011839)2.05050070
9011 pairs of ribs (HP:0000878)2.04629120
91Secondary amenorrhea (HP:0000869)2.04130154
92IgG deficiency (HP:0004315)2.02843683
93Dicarboxylic aciduria (HP:0003215)2.01988690
94Abnormality of dicarboxylic acid metabolism (HP:0010995)2.01988690
95Hepatosplenomegaly (HP:0001433)2.01921397
96Lymphoma (HP:0002665)2.01790943
97Nausea (HP:0002018)2.01273345
98Myelodysplasia (HP:0002863)2.01008415
99Abnormality of aromatic amino acid family metabolism (HP:0004338)2.00905032
100Severe combined immunodeficiency (HP:0004430)2.00255474
101Abnormal trabecular bone morphology (HP:0100671)1.99481284
102Methylmalonic aciduria (HP:0012120)1.98997186
103Increased muscle lipid content (HP:0009058)1.97777404
104Carpal bone hypoplasia (HP:0001498)1.97090380
105Chronic obstructive pulmonary disease (HP:0006510)1.96311387
106Obstructive lung disease (HP:0006536)1.96311387
107Granulocytopenia (HP:0001913)1.95957261
108Respiratory failure (HP:0002878)1.93471773
109Abnormality of T cells (HP:0002843)1.93157940
110Abnormal spermatogenesis (HP:0008669)1.92848091
111Combined immunodeficiency (HP:0005387)1.92085671
112Cholecystitis (HP:0001082)1.90477952
113Abnormal gallbladder physiology (HP:0012438)1.90477952
114Rhabdomyolysis (HP:0003201)1.89167950
115Chromsome breakage (HP:0040012)1.88802653
116Hypergonadotropic hypogonadism (HP:0000815)1.88645539
117Cellular immunodeficiency (HP:0005374)1.88029781
118Abnormality of renal resorption (HP:0011038)1.87893426
119T lymphocytopenia (HP:0005403)1.87824095
120X-linked dominant inheritance (HP:0001423)1.86848944
121Recurrent skin infections (HP:0001581)1.86172597
122Aplasia/Hypoplasia of the patella (HP:0006498)1.85999266
123Abnormality of eosinophils (HP:0001879)1.85945625
124Glycosuria (HP:0003076)1.84901907
125Abnormality of urine glucose concentration (HP:0011016)1.84901907
126Cerebral palsy (HP:0100021)1.81956660
127Severe visual impairment (HP:0001141)1.81340215
128Delusions (HP:0000746)1.80154039
129Ragged-red muscle fibers (HP:0003200)1.78939639
130Nemaline bodies (HP:0003798)1.78561032
131Gliosis (HP:0002171)1.78382833
132Increased serum ferritin (HP:0003281)1.78178280
133Paralysis (HP:0003470)1.76023046
134Constricted visual fields (HP:0001133)1.75559426
135Hypokinesia (HP:0002375)1.69668496
136Muscle fiber inclusion bodies (HP:0100299)1.66793207
137Opisthotonus (HP:0002179)1.65587542
138Neutropenia (HP:0001875)1.64782913
139Congenital stationary night blindness (HP:0007642)1.63360484
140Myopathic facies (HP:0002058)1.62644166
141Methylmalonic acidemia (HP:0002912)1.60561907
142Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.60230886
143Blindness (HP:0000618)1.59881401

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME23.84467278
2STK163.45952856
3VRK23.11613195
4EIF2AK12.92041434
5PIM22.83954651
6BUB12.62075013
7TRIM282.49709401
8EIF2AK32.45557345
9VRK12.36897975
10WEE12.21621238
11SRPK12.10842948
12PLK41.98383215
13MUSK1.96515658
14ACVR1B1.88517813
15MAP4K11.87949830
16KIT1.82514036
17TXK1.75886626
18PDK21.73503570
19MAP3K121.73334448
20TLK11.72853946
21TEC1.65254097
22PBK1.57564528
23ARAF1.50773877
24IKBKB1.48463047
25TYK21.45519973
26TBK11.43702940
27MST41.40872269
28IRAK41.40375589
29KDR1.39536132
30MYLK1.39510683
31FLT31.37767709
32IKBKE1.35008550
33CDC71.32635485
34MARK31.28536636
35DAPK11.28446719
36MAP3K141.27514039
37JAK31.26129600
38PIM11.26024470
39BCKDK1.25726008
40RPS6KA41.25028171
41NEK11.23688771
42EIF2AK21.21903141
43BTK1.20961134
44MKNK11.20018233
45MAP4K21.19502729
46BMPR1B1.18206266
47BLK1.17493119
48NUAK11.12348081
49CDK81.11675871
50BRAF1.09278086
51FES1.06797675
52OBSCN1.06655858
53LIMK11.06635284
54ZAP701.03005885
55TAF11.01115983
56IRAK31.01055326
57TESK21.00784504
58PLK10.99719191
59TGFBR10.97356013
60TSSK60.97078499
61ZAK0.96871355
62GRK70.96766788
63PINK10.96641016
64BRSK20.94644592
65CSNK1G30.93391062
66DYRK30.92927848
67TAOK30.92893252
68AURKB0.92564370
69CDK70.92030254
70SIK30.91284754
71STK100.90868513
72PIK3CG0.90678903
73DYRK20.89349982
74ABL20.89123553
75ADRBK20.87905660
76ATR0.86130972
77CSF1R0.86075908
78MAPKAPK30.85084844
79MAP2K30.84758212
80PAK10.83762349
81MKNK20.83320466
82BMPR20.82592668
83SYK0.80673242
84STK40.80144173
85PRKCI0.80010508
86CHUK0.78616664
87LYN0.78090471
88WNK30.77942425
89NLK0.76980388
90STK38L0.76734414
91TNK20.75467560
92ILK0.75127396
93GRK10.74200756
94GRK60.72604944
95NEK20.71502076
96NEK90.71452493
97RPS6KA50.71218407
98PHKG20.69779841
99PHKG10.69779841
100PASK0.69327451
101CCNB10.69326711
102TAOK20.68851891
103PAK40.68768595
104CSNK1G20.67049493
105CSNK2A10.66066661
106RAF10.66031050
107TESK10.65593246
108TGFBR20.64728100
109SCYL20.64373095
110CSNK1G10.64064216
111AURKA0.63796224
112MAP3K110.63587653
113RPS6KB20.58629641
114TTK0.56650483
115LCK0.55825534
116PRKCQ0.55127166
117STK240.54632425
118RIPK40.54499105
119LRRK20.54356460
120MATK0.54083060
121PLK30.53656472
122MOS0.52681462
123MAP3K80.47962725
124YES10.46985025
125BRSK10.44848612
126CAMK2G0.44604068
127CSNK1A1L0.43774207
128MAP3K130.43452266
129CSNK2A20.42489445
130NME10.41757401
131CDK190.41724883
132MAPKAPK50.41374528
133PRKCD0.41345153
134CDK40.40703079
135TAOK10.40636571
136MAP3K50.39338733
137MAPKAPK20.39282556
138TRPM70.39234614

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.21548967
2Proteasome_Homo sapiens_hsa030503.89272102
3DNA replication_Homo sapiens_hsa030303.72951760
4RNA polymerase_Homo sapiens_hsa030203.45333789
5Mismatch repair_Homo sapiens_hsa034302.90089200
6Pyrimidine metabolism_Homo sapiens_hsa002402.48014676
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.47997705
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.44159627
9Homologous recombination_Homo sapiens_hsa034402.44145834
10Base excision repair_Homo sapiens_hsa034102.35371605
11Protein export_Homo sapiens_hsa030602.26581675
12Spliceosome_Homo sapiens_hsa030402.21337125
13Nucleotide excision repair_Homo sapiens_hsa034202.17820115
14Basal transcription factors_Homo sapiens_hsa030222.08525863
15Oxidative phosphorylation_Homo sapiens_hsa001901.90100302
16RNA degradation_Homo sapiens_hsa030181.87789367
17Parkinsons disease_Homo sapiens_hsa050121.86586605
18Non-homologous end-joining_Homo sapiens_hsa034501.79607169
19RNA transport_Homo sapiens_hsa030131.69840769
20Allograft rejection_Homo sapiens_hsa053301.68187176
21Fanconi anemia pathway_Homo sapiens_hsa034601.57833390
22Graft-versus-host disease_Homo sapiens_hsa053321.55451588
23Huntingtons disease_Homo sapiens_hsa050161.48776556
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.46970554
25Cell cycle_Homo sapiens_hsa041101.46438516
26Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.43054606
27Collecting duct acid secretion_Homo sapiens_hsa049661.40284278
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.40055822
29One carbon pool by folate_Homo sapiens_hsa006701.39544136
30Purine metabolism_Homo sapiens_hsa002301.35195144
31Cardiac muscle contraction_Homo sapiens_hsa042601.32456639
32Primary immunodeficiency_Homo sapiens_hsa053401.25685474
33Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.25332667
34Herpes simplex infection_Homo sapiens_hsa051681.18528294
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15413911
36Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.15305934
37Asthma_Homo sapiens_hsa053101.14041124
38Legionellosis_Homo sapiens_hsa051341.12605507
39Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.11944555
40p53 signaling pathway_Homo sapiens_hsa041151.11919208
41Folate biosynthesis_Homo sapiens_hsa007901.10247316
42Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.08909836
43Antigen processing and presentation_Homo sapiens_hsa046121.08000975
44Intestinal immune network for IgA production_Homo sapiens_hsa046721.07572681
45Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.05970848
46SNARE interactions in vesicular transport_Homo sapiens_hsa041301.05819723
47Measles_Homo sapiens_hsa051621.04999264
48Alzheimers disease_Homo sapiens_hsa050101.00742283
49Leishmaniasis_Homo sapiens_hsa051401.00561077
50Epstein-Barr virus infection_Homo sapiens_hsa051691.00169222
51Carbon metabolism_Homo sapiens_hsa012000.97118431
52Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.96014170
53Sulfur metabolism_Homo sapiens_hsa009200.94680533
54Other glycan degradation_Homo sapiens_hsa005110.92314075
55Autoimmune thyroid disease_Homo sapiens_hsa053200.90727693
56Pyruvate metabolism_Homo sapiens_hsa006200.90196396
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88849983
58Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.87900573
59NF-kappa B signaling pathway_Homo sapiens_hsa040640.87222470
60Viral myocarditis_Homo sapiens_hsa054160.86865520
61RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.86303786
62Hematopoietic cell lineage_Homo sapiens_hsa046400.86222217
63Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.85229184
64Pentose phosphate pathway_Homo sapiens_hsa000300.74922331
65Propanoate metabolism_Homo sapiens_hsa006400.74733039
66Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.74460566
67Malaria_Homo sapiens_hsa051440.72570244
68Biosynthesis of amino acids_Homo sapiens_hsa012300.72461765
69Type I diabetes mellitus_Homo sapiens_hsa049400.71208444
70Drug metabolism - other enzymes_Homo sapiens_hsa009830.70887087
71NOD-like receptor signaling pathway_Homo sapiens_hsa046210.69743920
72Glutathione metabolism_Homo sapiens_hsa004800.66196109
73mRNA surveillance pathway_Homo sapiens_hsa030150.63730415
74Arachidonic acid metabolism_Homo sapiens_hsa005900.62774986
75Apoptosis_Homo sapiens_hsa042100.62373328
76Phototransduction_Homo sapiens_hsa047440.61764900
77Influenza A_Homo sapiens_hsa051640.61209890
78Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.60562596
79Rheumatoid arthritis_Homo sapiens_hsa053230.59277698
80Shigellosis_Homo sapiens_hsa051310.58018629
81Toll-like receptor signaling pathway_Homo sapiens_hsa046200.54794070
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.53782669
83Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.51104097
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51031874
85Pertussis_Homo sapiens_hsa051330.50192667
86Vibrio cholerae infection_Homo sapiens_hsa051100.50158151
87Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49458715
88Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48789074
89Metabolic pathways_Homo sapiens_hsa011000.46884280
90Systemic lupus erythematosus_Homo sapiens_hsa053220.46295933
91Butanoate metabolism_Homo sapiens_hsa006500.45574351
92Hepatitis B_Homo sapiens_hsa051610.43040191
93Viral carcinogenesis_Homo sapiens_hsa052030.42257836
94Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.41417422
95Sulfur relay system_Homo sapiens_hsa041220.40563817
96Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.40492978
97Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38417613
98Fatty acid metabolism_Homo sapiens_hsa012120.36370337
99Staphylococcus aureus infection_Homo sapiens_hsa051500.35765720
100N-Glycan biosynthesis_Homo sapiens_hsa005100.35108433
101Sphingolipid metabolism_Homo sapiens_hsa006000.35011423
102Fatty acid elongation_Homo sapiens_hsa000620.34599184
103Cysteine and methionine metabolism_Homo sapiens_hsa002700.34428619
104Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33956083
105Lysosome_Homo sapiens_hsa041420.32470061
106Arginine and proline metabolism_Homo sapiens_hsa003300.30563109
107Phagosome_Homo sapiens_hsa041450.29211712
108Selenocompound metabolism_Homo sapiens_hsa004500.28711431
109Transcriptional misregulation in cancer_Homo sapiens_hsa052020.28383054
110Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28155665
111Peroxisome_Homo sapiens_hsa041460.27699918
112Regulation of autophagy_Homo sapiens_hsa041400.27674939
113Synaptic vesicle cycle_Homo sapiens_hsa047210.27551426
114Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27423998
115HTLV-I infection_Homo sapiens_hsa051660.27322832
116Tuberculosis_Homo sapiens_hsa051520.26934309
117TNF signaling pathway_Homo sapiens_hsa046680.26270095
118Thyroid cancer_Homo sapiens_hsa052160.25917693
119Steroid biosynthesis_Homo sapiens_hsa001000.25853882
120Primary bile acid biosynthesis_Homo sapiens_hsa001200.25344437
121Linoleic acid metabolism_Homo sapiens_hsa005910.23967747
122Galactose metabolism_Homo sapiens_hsa000520.23594349
123Osteoclast differentiation_Homo sapiens_hsa043800.21490733
124Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.21469749
125Tryptophan metabolism_Homo sapiens_hsa003800.20674997
126Vitamin B6 metabolism_Homo sapiens_hsa007500.19954613
127B cell receptor signaling pathway_Homo sapiens_hsa046620.18739014
128Fructose and mannose metabolism_Homo sapiens_hsa000510.18402583
129Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.18080973

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