LSM14B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1layer formation in cerebral cortex (GO:0021819)4.87729347
2cell migration in hindbrain (GO:0021535)4.39391386
3synaptic vesicle maturation (GO:0016188)3.93861760
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.89708955
5locomotory exploration behavior (GO:0035641)3.85053364
6negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.72785291
7regulation of short-term neuronal synaptic plasticity (GO:0048172)3.64844826
8focal adhesion assembly (GO:0048041)3.63759775
9cell-substrate adherens junction assembly (GO:0007045)3.63759775
10negative regulation of potassium ion transmembrane transport (GO:1901380)3.62035068
11regulation of mammary gland epithelial cell proliferation (GO:0033599)3.46389738
12regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.46222675
13establishment of nucleus localization (GO:0040023)3.40389184
14cell-cell junction maintenance (GO:0045217)3.39295565
15synaptic vesicle docking involved in exocytosis (GO:0016081)3.33070123
16pre-miRNA processing (GO:0031054)3.31691492
17plasma membrane repair (GO:0001778)3.30632443
18semaphorin-plexin signaling pathway (GO:0071526)3.20749113
19regulation of chromatin binding (GO:0035561)3.20386714
20protein retention in ER lumen (GO:0006621)3.19421181
21nucleosome disassembly (GO:0006337)3.19019080
22protein-DNA complex disassembly (GO:0032986)3.19019080
23protein localization to endosome (GO:0036010)3.18112884
24mitotic chromosome condensation (GO:0007076)3.17830232
25positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling3.16026275
26peptidyl-lysine dimethylation (GO:0018027)3.14559634
27regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.13994935
28positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.12598902
29regulation of synapse structural plasticity (GO:0051823)3.12433213
30dendritic spine morphogenesis (GO:0060997)3.11851164
31maternal placenta development (GO:0001893)3.11108888
32glial cell proliferation (GO:0014009)3.11088627
33cell communication by electrical coupling (GO:0010644)3.10201114
34mRNA stabilization (GO:0048255)3.07192103
35RNA stabilization (GO:0043489)3.07192103
36pyrimidine nucleobase catabolic process (GO:0006208)3.05541964
37dendrite morphogenesis (GO:0048813)3.05285135
38negative regulation of erythrocyte differentiation (GO:0045647)3.03803884
39maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.02124936
40regulation of glucose import in response to insulin stimulus (GO:2001273)3.01452526
41vocalization behavior (GO:0071625)2.99485665
42cytoskeletal anchoring at plasma membrane (GO:0007016)2.97105235
43cerebellar granule cell differentiation (GO:0021707)2.96244769
44positive regulation of synapse maturation (GO:0090129)2.95893668
45cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.95440616
46regulation of nucleobase-containing compound transport (GO:0032239)2.92127779
47negative regulation of organelle assembly (GO:1902116)2.91713301
48regulation of hippo signaling (GO:0035330)2.90876401
49regulation of glutamate receptor signaling pathway (GO:1900449)2.90342903
50response to parathyroid hormone (GO:0071107)2.88946009
51intracellular estrogen receptor signaling pathway (GO:0030520)2.88566676
52establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.87896997
53mitochondrion transport along microtubule (GO:0047497)2.87896997
54regulation of NFAT protein import into nucleus (GO:0051532)2.87655185
55activation of protein kinase A activity (GO:0034199)2.86516414
56heterochromatin organization (GO:0070828)2.86347941
57neuromuscular process controlling balance (GO:0050885)2.83949247
58cardiac myofibril assembly (GO:0055003)2.83586239
59proline transport (GO:0015824)2.83516531
60regulation of RNA export from nucleus (GO:0046831)2.82934972
61regulation of histone H3-K27 methylation (GO:0061085)2.79977563
62activation of Rac GTPase activity (GO:0032863)2.79273260
63exploration behavior (GO:0035640)2.76655890
64positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.75859596
65regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.75859596
66apoptotic process involved in morphogenesis (GO:0060561)2.72869924
67regulation of synaptic vesicle exocytosis (GO:2000300)2.72059980
68neural tube development (GO:0021915)2.70936795
69regulation of dendritic spine morphogenesis (GO:0061001)2.70322513
70paraxial mesoderm development (GO:0048339)2.70246236
71axonal fasciculation (GO:0007413)2.70204531
72body morphogenesis (GO:0010171)2.69912923
73mating behavior (GO:0007617)2.69459183
743-UTR-mediated mRNA stabilization (GO:0070935)2.69366959
75regulation of membrane repolarization (GO:0060306)2.69332486
76epithelial cell-cell adhesion (GO:0090136)2.68783769
77retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.68631847
78spliceosomal tri-snRNP complex assembly (GO:0000244)2.68464879
79convergent extension (GO:0060026)2.65884695
80embryonic retina morphogenesis in camera-type eye (GO:0060059)2.65680968
81adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.64654406
82glutamate secretion (GO:0014047)2.64206783
83negative regulation of cell size (GO:0045792)2.63961678
84central nervous system projection neuron axonogenesis (GO:0021952)2.63943021
85axon extension (GO:0048675)2.63772007
86cellular response to epidermal growth factor stimulus (GO:0071364)2.63206949
87DNA unwinding involved in DNA replication (GO:0006268)2.63017133
88modulation by virus of host morphology or physiology (GO:0019048)2.61190569
89RNA localization (GO:0006403)2.60109769
90eye morphogenesis (GO:0048592)2.59572488
91epithelial cell differentiation involved in prostate gland development (GO:0060742)2.59567155
92sodium ion export (GO:0071436)2.58271279
93G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.55676620
94embryonic foregut morphogenesis (GO:0048617)2.55460720
95embryonic eye morphogenesis (GO:0048048)2.55408704
96cytoplasmic mRNA processing body assembly (GO:0033962)2.55136266
97regulation of neuronal synaptic plasticity (GO:0048168)2.54723010
98cell communication involved in cardiac conduction (GO:0086065)2.53935227
99regulation of ARF GTPase activity (GO:0032312)2.53694163
100negative regulation of fatty acid transport (GO:2000192)2.53237430
101embryonic camera-type eye morphogenesis (GO:0048596)2.52746424
102COPI coating of Golgi vesicle (GO:0048205)2.52713904
103Golgi transport vesicle coating (GO:0048200)2.52713904
104insulin-like growth factor receptor signaling pathway (GO:0048009)2.52526264
105regulation of synaptic vesicle transport (GO:1902803)2.52307710
106cell-substrate junction assembly (GO:0007044)2.51601627
107regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.49981684
108dendritic spine organization (GO:0097061)2.49743043
109neuron recognition (GO:0008038)2.48955075
110regulation of long-term neuronal synaptic plasticity (GO:0048169)2.47565705
111cerebellar Purkinje cell layer development (GO:0021680)2.47359280
112cerebellum development (GO:0021549)2.45775953
113regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.43761514
114regulation of early endosome to late endosome transport (GO:2000641)2.43728774
115stress fiber assembly (GO:0043149)2.43395781
116membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.43229631
117innervation (GO:0060384)2.43167829
118synaptic vesicle exocytosis (GO:0016079)2.42919912
119dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.42415832
120nucleobase catabolic process (GO:0046113)2.42272398
121histone H3-K36 demethylation (GO:0070544)2.41987395
122Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.41093052
123protein targeting to plasma membrane (GO:0072661)2.40693324
124neurotransmitter secretion (GO:0007269)2.40471148
125nuclear pore complex assembly (GO:0051292)2.39573770
126protein localization to microtubule (GO:0035372)2.39277683
127corticosteroid receptor signaling pathway (GO:0031958)2.39108559
128establishment of mitochondrion localization (GO:0051654)2.38804019
129protein localization to synapse (GO:0035418)2.38625817
130hippo signaling (GO:0035329)2.38190509
131regulation of ARF protein signal transduction (GO:0032012)2.37870695
132positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.37603791
133organelle transport along microtubule (GO:0072384)2.37096252
134camera-type eye morphogenesis (GO:0048593)2.36806860
135cell junction maintenance (GO:0034331)2.36777292
136response to epidermal growth factor (GO:0070849)2.36222199
137nucleus localization (GO:0051647)2.35914245
138chromosome condensation (GO:0030261)2.35401306
139neuron projection extension (GO:1990138)2.35201750
140histone H2A monoubiquitination (GO:0035518)2.34943837
141cortical actin cytoskeleton organization (GO:0030866)2.34477126
142negative regulation of sodium ion transport (GO:0010766)2.33849498
143regulation of glycogen (starch) synthase activity (GO:2000465)2.33784720
144planar cell polarity pathway involved in neural tube closure (GO:0090179)2.33494787
145negative regulation of histone methylation (GO:0031061)2.33086784
146positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.32706008
147basement membrane organization (GO:0071711)2.32593381
148intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)2.32264014
149regulation of clathrin-mediated endocytosis (GO:2000369)2.32025391
150peptidyl-threonine phosphorylation (GO:0018107)2.31972383
151peptidyl-arginine omega-N-methylation (GO:0035247)2.31276333
152glucose 6-phosphate metabolic process (GO:0051156)2.31222585
153positive regulation of protein export from nucleus (GO:0046827)2.30251213
154gastrulation with mouth forming second (GO:0001702)2.29401459
155clathrin coat assembly (GO:0048268)2.28481472
156dopamine receptor signaling pathway (GO:0007212)2.27789956
157neuron cell-cell adhesion (GO:0007158)2.27441862
158membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.25049291
159negative regulation of catenin import into nucleus (GO:0035414)2.24141147
160piRNA metabolic process (GO:0034587)2.23931991
161regulation of potassium ion transmembrane transporter activity (GO:1901016)2.22909912
162cerebral cortex development (GO:0021987)2.22816332
163adherens junction assembly (GO:0034333)2.22473423
164regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.21929270
165positive regulation of axon extension (GO:0045773)2.21333315
166ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.20213103
167positive regulation of dendritic spine morphogenesis (GO:0061003)2.20122333
168glucocorticoid receptor signaling pathway (GO:0042921)2.19428823
169membrane repolarization (GO:0086009)2.18905338
170cardiac muscle contraction (GO:0060048)2.17839867
171cardiac muscle cell development (GO:0055013)2.16866707
172ovulation cycle (GO:0042698)2.16832070
173negative regulation of microtubule polymerization (GO:0031115)2.16033007

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.94972687
2EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse3.06133202
3THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.84470622
4ZFP281_18757296_ChIP-ChIP_E14_Mouse2.65059982
5TP63_17297297_ChIP-ChIP_HaCaT_Human2.47578395
6ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.41073406
7RARB_27405468_Chip-Seq_BRAIN_Mouse2.39533908
8VDR_21846776_ChIP-Seq_THP-1_Human2.36954835
9TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.31830113
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.29665029
11KDM2B_26808549_Chip-Seq_K562_Human2.25782789
12ZFP281_27345836_Chip-Seq_ESCs_Mouse2.25375800
13WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.23690116
14SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.18433961
15STAT6_21828071_ChIP-Seq_BEAS2B_Human2.16801977
16ELK3_25401928_ChIP-Seq_HUVEC_Human2.07732303
17* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05359487
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.00186860
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.99079807
20SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.94162126
21KDM2B_26808549_Chip-Seq_SUP-B15_Human1.94026765
22ESR2_21235772_ChIP-Seq_MCF-7_Human1.92330497
23KDM2B_26808549_Chip-Seq_DND41_Human1.90668991
24DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.89356627
25EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.88398532
26RNF2_18974828_ChIP-Seq_MESCs_Mouse1.86337911
27EZH2_18974828_ChIP-Seq_MESCs_Mouse1.86337911
28EGR1_19374776_ChIP-ChIP_THP-1_Human1.85814225
29RARG_19884340_ChIP-ChIP_MEFs_Mouse1.82162721
30TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.77130047
31JARID2_20064375_ChIP-Seq_MESCs_Mouse1.74528506
32MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.74508979
33ZNF263_19887448_ChIP-Seq_K562_Human1.74260277
34RNF2_27304074_Chip-Seq_ESCs_Mouse1.74232566
35KDM2B_26808549_Chip-Seq_JURKAT_Human1.74014593
36DROSHA_22980978_ChIP-Seq_HELA_Human1.72490596
37EZH2_27304074_Chip-Seq_ESCs_Mouse1.70875016
38* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.69419970
39NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.68939758
40E2F7_22180533_ChIP-Seq_HELA_Human1.67242775
41CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.66818276
42CLOCK_20551151_ChIP-Seq_293T_Human1.60266464
43ERG_21242973_ChIP-ChIP_JURKAT_Human1.59108619
44TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.58392788
45JARID2_20075857_ChIP-Seq_MESCs_Mouse1.52866075
46SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.52658538
47* EZH2_27294783_Chip-Seq_ESCs_Mouse1.52106511
48NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.50427580
49* RING1B_27294783_Chip-Seq_NPCs_Mouse1.48412182
50CREB1_26743006_Chip-Seq_LNCaP_Human1.47945184
51REST_21632747_ChIP-Seq_MESCs_Mouse1.46268197
52* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.46064402
53SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.45819134
54RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.45117987
55KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.43931461
56MTF2_20144788_ChIP-Seq_MESCs_Mouse1.42857080
57P68_20966046_ChIP-Seq_HELA_Human1.41244105
58SALL1_21062744_ChIP-ChIP_HESCs_Human1.40939165
59RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.39727164
60P300_27058665_Chip-Seq_ZR-75-30cells_Human1.39710890
61REST_18959480_ChIP-ChIP_MESCs_Mouse1.39084938
62SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.37525341
63* TET1_21451524_ChIP-Seq_MESCs_Mouse1.36458222
64RBPJ_22232070_ChIP-Seq_NCS_Mouse1.36079889
65* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.36054812
66WT1_25993318_ChIP-Seq_PODOCYTE_Human1.35678524
67CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.35131776
68KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.33983043
69KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.33527602
70* RING1B_27294783_Chip-Seq_ESCs_Mouse1.33215056
71ISL1_27105846_Chip-Seq_CPCs_Mouse1.32147258
72KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.31316968
73ESR1_15608294_ChIP-ChIP_MCF-7_Human1.31165204
74KLF4_18555785_ChIP-Seq_MESCs_Mouse1.30884328
75FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.30572912
76RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.29360194
77TCF7_22412390_ChIP-Seq_EML_Mouse1.29147405
78ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.27742854
79CTCF_27219007_Chip-Seq_ERYTHROID_Human1.27296525
80CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.26772533
81CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.26725109
82DNAJC2_21179169_ChIP-ChIP_NT2_Human1.26013230
83ESR1_20079471_ChIP-ChIP_T-47D_Human1.25458831
84* MYC_22102868_ChIP-Seq_BL_Human1.25252529
85SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.24088943
86SA1_27219007_Chip-Seq_ERYTHROID_Human1.22830501
87EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.21634400
88ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.20799411
89* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.20751707
90SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20012951
91SRY_22984422_ChIP-ChIP_TESTIS_Rat1.19098773
92MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.18547580
93AR_19668381_ChIP-Seq_PC3_Human1.18123206
94CTCF_27219007_Chip-Seq_Bcells_Human1.16878500
95TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.14760211
96SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.13369520
97NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.12711443
98PKCTHETA_26484144_Chip-Seq_BREAST_Human1.12279001
99NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.10275346
100SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.10233136
101OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.09430954
102NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.08991068
103HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.08618209
104UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.08090713
105VDR_24763502_ChIP-Seq_THP-1_Human1.07227387
106* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06520963
107ATF3_27146783_Chip-Seq_COLON_Human1.05864952
108POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.05355140
109EP300_21415370_ChIP-Seq_HL-1_Mouse1.05108325
110SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.04368976
111NANOG_21062744_ChIP-ChIP_HESCs_Human1.04248272
112MAF_26560356_Chip-Seq_TH1_Human1.03705557
113* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03282771
114HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.02573942
115TP53_20018659_ChIP-ChIP_R1E_Mouse1.01433301
116NFIB_24661679_ChIP-Seq_LUNG_Mouse1.01267434
117* LXR_22292898_ChIP-Seq_THP-1_Human0.99760299
118SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.98631675
119* NCOR1_26117541_ChIP-Seq_K562_Human0.98517358
120EED_16625203_ChIP-ChIP_MESCs_Mouse0.96896042
121RACK7_27058665_Chip-Seq_MCF-7_Human0.96441002
122SMC4_20622854_ChIP-Seq_HELA_Human0.94845787
123SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.94772667
124CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94496711
125TET1_21490601_ChIP-Seq_MESCs_Mouse0.93785210
126OCT4_19829295_ChIP-Seq_ESCs_Human0.93306978
127VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.93138166
128* STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.92786265
129KAP1_27257070_Chip-Seq_ESCs_Mouse0.92671218
130ZFX_18555785_ChIP-Seq_MESCs_Mouse0.92197381
131YAP1_20516196_ChIP-Seq_MESCs_Mouse0.90833461
132TBX20_22080862_ChIP-Seq_HEART_Mouse0.89890761
133TBX20_22328084_ChIP-Seq_HEART_Mouse0.89890761
134SOX2_21211035_ChIP-Seq_LN229_Gbm0.89720688
135* RUNX1_27514584_Chip-Seq_MCF-7_Human0.89534234
136PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.89381525
137TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.88943778
138TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.88413247
139POU5F1_16518401_ChIP-PET_MESCs_Mouse0.87776699
140ZNF217_24962896_ChIP-Seq_MCF-7_Human0.87696009
141ZNF274_21170338_ChIP-Seq_K562_Hela0.86860712
142TP53_22127205_ChIP-Seq_IMR90_Human0.85475691
143SMAD4_21741376_ChIP-Seq_HESCs_Human0.85390254
144KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.85025988
145POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.84784525
146ELK4_26923725_Chip-Seq_MESODERM_Mouse0.84595518

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.36532418
2MP0005409_darkened_coat_color2.92340901
3MP0003705_abnormal_hypodermis_morpholog2.78572422
4MP0005451_abnormal_body_composition2.53674526
5MP0003646_muscle_fatigue2.52522750
6MP0004270_analgesia2.32980738
7MP0002653_abnormal_ependyma_morphology2.32901930
8MP0003635_abnormal_synaptic_transmissio2.28017544
9MP0005257_abnormal_intraocular_pressure2.26014219
10MP0005187_abnormal_penis_morphology2.17575258
11MP0004858_abnormal_nervous_system2.11375161
12MP0000537_abnormal_urethra_morphology2.08423254
13MP0000751_myopathy2.05829918
14MP0002063_abnormal_learning/memory/cond1.95028290
15MP0002089_abnormal_postnatal_growth/wei1.92857697
16MP0000778_abnormal_nervous_system1.91561822
17MP0003787_abnormal_imprinting1.89647138
18MP0009780_abnormal_chondrocyte_physiolo1.82703649
19MP0002837_dystrophic_cardiac_calcinosis1.74638938
20MP0009053_abnormal_anal_canal1.70413797
21MP0003283_abnormal_digestive_organ1.69314442
22MP0005076_abnormal_cell_differentiation1.69254520
23MP0000566_synostosis1.68652628
24MP0003119_abnormal_digestive_system1.68580349
25MP0000747_muscle_weakness1.67707853
26MP0005623_abnormal_meninges_morphology1.66702831
27MP0004885_abnormal_endolymph1.66069428
28MP0004233_abnormal_muscle_weight1.65670594
29MP0003566_abnormal_cell_adhesion1.59376321
30MP0010234_abnormal_vibrissa_follicle1.57504786
31MP0005058_abnormal_lysosome_morphology1.55407225
32MP0004084_abnormal_cardiac_muscle1.50478207
33MP0004811_abnormal_neuron_physiology1.49464211
34MP0003123_paternal_imprinting1.46054873
35MP0004087_abnormal_muscle_fiber1.44369376
36MP0000955_abnormal_spinal_cord1.43742977
37MP0003861_abnormal_nervous_system1.43408148
38MP0009278_abnormal_bone_marrow1.41066421
39MP0008260_abnormal_autophagy1.40271267
40MP0000569_abnormal_digit_pigmentation1.39414403
41MP0003385_abnormal_body_wall1.38356499
42MP0002822_catalepsy1.38241174
43MP0001849_ear_inflammation1.34859235
44MP0004264_abnormal_extraembryonic_tissu1.34301828
45MP0000579_abnormal_nail_morphology1.33913191
46MP0003121_genomic_imprinting1.29754140
47MP0005666_abnormal_adipose_tissue1.29590895
48MP0002184_abnormal_innervation1.28627348
49MP0002152_abnormal_brain_morphology1.28341756
50MP0003091_abnormal_cell_migration1.26496240
51MP0002909_abnormal_adrenal_gland1.26204292
52MP0009745_abnormal_behavioral_response1.25453668
53MP0000678_abnormal_parathyroid_gland1.24682891
54MP0003453_abnormal_keratinocyte_physiol1.24349196
55MP0003137_abnormal_impulse_conducting1.24172997
56MP0001346_abnormal_lacrimal_gland1.23994647
57MP0000003_abnormal_adipose_tissue1.22815110
58MP0002734_abnormal_mechanical_nocicepti1.22193227
59MP0003634_abnormal_glial_cell1.21372448
60MP0002234_abnormal_pharynx_morphology1.20634722
61MP0000534_abnormal_ureter_morphology1.19597223
62MP0002084_abnormal_developmental_patter1.17862345
63MP0003172_abnormal_lysosome_physiology1.17032238
64MP0005394_taste/olfaction_phenotype1.16069870
65MP0005499_abnormal_olfactory_system1.16069870
66MP0004215_abnormal_myocardial_fiber1.15532992
67MP0005375_adipose_tissue_phenotype1.14598500
68MP0002572_abnormal_emotion/affect_behav1.14435448
69MP0003880_abnormal_central_pattern1.14410608
70MP0002796_impaired_skin_barrier1.14271297
71MP0003115_abnormal_respiratory_system1.14244367
72MP0004130_abnormal_muscle_cell1.13511311
73MP0005248_abnormal_Harderian_gland1.13494986
74MP0004085_abnormal_heartbeat1.12416341
75MP0003942_abnormal_urinary_system1.11243036
76MP0004036_abnormal_muscle_relaxation1.09973238
77MP0002064_seizures1.09929835
78MP0008961_abnormal_basal_metabolism1.08470558
79MP0000733_abnormal_muscle_development1.08416229
80MP0000750_abnormal_muscle_regeneration1.06915415
81MP0009046_muscle_twitch1.06073734
82MP0004145_abnormal_muscle_electrophysio1.05865247
83MP0002882_abnormal_neuron_morphology1.05574976
84MP0010630_abnormal_cardiac_muscle1.05552969
85MP0002269_muscular_atrophy1.05092177
86MP0002249_abnormal_larynx_morphology1.04493731
87MP0002085_abnormal_embryonic_tissue1.03045354
88MP0004197_abnormal_fetal_growth/weight/1.02026225
89MP0005423_abnormal_somatic_nervous1.01934576
90MP0000428_abnormal_craniofacial_morphol1.01213770
91MP0008877_abnormal_DNA_methylation1.01198123
92MP0010030_abnormal_orbit_morphology1.00819506
93MP0002733_abnormal_thermal_nociception1.00507294
94MP0002697_abnormal_eye_size0.99511091
95MP0002106_abnormal_muscle_physiology0.98859660
96MP0008438_abnormal_cutaneous_collagen0.98793772
97MP0003935_abnormal_craniofacial_develop0.98559239
98MP0003879_abnormal_hair_cell0.98455518
99MP0002092_abnormal_eye_morphology0.98411714
100MP0003329_amyloid_beta_deposits0.98360975
101MP0002557_abnormal_social/conspecific_i0.98074130
102MP0006138_congestive_heart_failure0.97319115
103MP0009379_abnormal_foot_pigmentation0.97030212
104MP0003937_abnormal_limbs/digits/tail_de0.96776076
105MP0000350_abnormal_cell_proliferation0.96364599
106MP0005620_abnormal_muscle_contractility0.95292708
107MP0004924_abnormal_behavior0.94269554
108MP0005386_behavior/neurological_phenoty0.94269554
109MP0002080_prenatal_lethality0.94114136
110MP0000462_abnormal_digestive_system0.93642313
111MP0002877_abnormal_melanocyte_morpholog0.93541559
112MP0009672_abnormal_birth_weight0.92834527
113MP0008789_abnormal_olfactory_epithelium0.92687179
114MP0002972_abnormal_cardiac_muscle0.92578978
115MP0000759_abnormal_skeletal_muscle0.92437710
116MP0004185_abnormal_adipocyte_glucose0.91534685
117MP0003567_abnormal_fetal_cardiomyocyte0.91459784
118MP0001348_abnormal_lacrimal_gland0.91390072
119MP0003122_maternal_imprinting0.90662979
120MP0003890_abnormal_embryonic-extraembry0.89985650
121MP0002081_perinatal_lethality0.88844699
122MP0010352_gastrointestinal_tract_polyps0.87905655
123MP0008569_lethality_at_weaning0.87847696
124MP0003755_abnormal_palate_morphology0.87300111
125MP0001730_embryonic_growth_arrest0.86440981
126MP0001672_abnormal_embryogenesis/_devel0.85559869
127MP0005380_embryogenesis_phenotype0.85559869
128MP0003111_abnormal_nucleus_morphology0.85149407
129MP0001486_abnormal_startle_reflex0.84705478
130MP0000631_abnormal_neuroendocrine_gland0.84545792
131MP0002066_abnormal_motor_capabilities/c0.83349162
132MP0005501_abnormal_skin_physiology0.83112833
133MP0003984_embryonic_growth_retardation0.83023384
134MP0002116_abnormal_craniofacial_bone0.82561277
135MP0002086_abnormal_extraembryonic_tissu0.82143573
136MP0001299_abnormal_eye_distance/0.81454636
137MP0002088_abnormal_embryonic_growth/wei0.78847186
138MP0002896_abnormal_bone_mineralization0.78446955
139MP0005621_abnormal_cell_physiology0.78331907
140MP0001697_abnormal_embryo_size0.77286486
141MP0009703_decreased_birth_body0.76999208
142MP0001340_abnormal_eyelid_morphology0.76381557
143MP0004381_abnormal_hair_follicle0.74644602
144MP0001915_intracranial_hemorrhage0.73465857
145MP0002009_preneoplasia0.71915285
146MP0000749_muscle_degeneration0.70888548

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)3.77892203
2Abnormality of the lower motor neuron (HP:0002366)3.73350663
3Myokymia (HP:0002411)3.44363175
4Insomnia (HP:0100785)3.10565207
5Asymmetry of the thorax (HP:0001555)2.90972277
6Renal duplication (HP:0000075)2.70582136
7Elfin facies (HP:0004428)2.70440253
8Sudden death (HP:0001699)2.68567079
9Renovascular hypertension (HP:0100817)2.61291970
10Pointed chin (HP:0000307)2.59338654
11Shallow orbits (HP:0000586)2.55558750
12Protrusio acetabuli (HP:0003179)2.53507958
13Abnormality of the astrocytes (HP:0100707)2.51023300
14Astrocytoma (HP:0009592)2.51023300
15Cortical dysplasia (HP:0002539)2.49834396
16Insidious onset (HP:0003587)2.46307006
17Termporal pattern (HP:0011008)2.46307006
18Overriding aorta (HP:0002623)2.44699577
19Ulnar bowing (HP:0003031)2.41703752
20Bundle branch block (HP:0011710)2.40858942
21Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.39009454
22Short 4th metacarpal (HP:0010044)2.39009454
23Abnormality of the 4th metacarpal (HP:0010012)2.36069998
24Long palpebral fissure (HP:0000637)2.32806002
25Cerebral inclusion bodies (HP:0100314)2.32511943
26Distal lower limb amyotrophy (HP:0008944)2.32352739
27Germ cell neoplasia (HP:0100728)2.32232565
28Subacute progressive viral hepatitis (HP:0006572)2.32162687
29Centrally nucleated skeletal muscle fibers (HP:0003687)2.31632768
30Cerebral aneurysm (HP:0004944)2.29824179
31Dysmetric saccades (HP:0000641)2.26120433
32Arnold-Chiari malformation (HP:0002308)2.19967659
33Amyotrophic lateral sclerosis (HP:0007354)2.18748762
34Abnormality of the Achilles tendon (HP:0005109)2.17904664
35Increased connective tissue (HP:0009025)2.17744026
36Visual hallucinations (HP:0002367)2.16885186
37Abnormality of the calcaneus (HP:0008364)2.14262125
38Hepatoblastoma (HP:0002884)2.14200749
39Apathy (HP:0000741)2.13782576
40Broad face (HP:0000283)2.12891094
41Neurofibrillary tangles (HP:0002185)2.12299179
42Distal lower limb muscle weakness (HP:0009053)2.10760253
43Disproportionate tall stature (HP:0001519)2.08441336
44Flat acetabular roof (HP:0003180)2.07321050
45Papillary thyroid carcinoma (HP:0002895)2.06378436
46Thin bony cortex (HP:0002753)2.06164597
47Difficulty running (HP:0009046)2.05809552
48Mitral regurgitation (HP:0001653)2.04544788
49Upper limb amyotrophy (HP:0009129)2.03982482
50Distal upper limb amyotrophy (HP:0007149)2.03982482
51Focal seizures (HP:0007359)2.03824001
52Abnormality of the distal phalanx of the thumb (HP:0009617)2.03337424
53Impaired vibration sensation in the lower limbs (HP:0002166)2.02273865
54Myopathic facies (HP:0002058)2.02184963
55Annular pancreas (HP:0001734)2.02184432
56Deep palmar crease (HP:0006191)2.01223512
57Abnormality of the corticospinal tract (HP:0002492)1.99547276
58Hypercortisolism (HP:0001578)1.99245104
59Ventricular fibrillation (HP:0001663)1.99158897
60Papilledema (HP:0001085)1.98291028
61Macroorchidism (HP:0000053)1.97956323
62Lymphangioma (HP:0100764)1.97895931
63Thin ribs (HP:0000883)1.97616922
64Sacral dimple (HP:0000960)1.97169019
65Urinary urgency (HP:0000012)1.96737331
66Lower limb amyotrophy (HP:0007210)1.96233091
67Abnormality of the diencephalon (HP:0010662)1.95831783
68Increased variability in muscle fiber diameter (HP:0003557)1.94729311
69Heterotopia (HP:0002282)1.94440958
70Flat cornea (HP:0007720)1.93971845
71Urinary bladder sphincter dysfunction (HP:0002839)1.93960432
72Hyperparathyroidism (HP:0000843)1.93056129
73Ankle clonus (HP:0011448)1.92975084
74Patellar dislocation (HP:0002999)1.91971380
75Action tremor (HP:0002345)1.90921619
76Back pain (HP:0003418)1.90567855
77Ependymoma (HP:0002888)1.89236156
78Depression (HP:0000716)1.89050037
79Diminished motivation (HP:0000745)1.88492114
80Genetic anticipation (HP:0003743)1.88057090
81Primary atrial arrhythmia (HP:0001692)1.87072228
82Hand muscle atrophy (HP:0009130)1.86941121
83Fibroma (HP:0010614)1.86712271
84Hamartoma of the eye (HP:0010568)1.86324597
85Abnormality of skeletal muscle fiber size (HP:0012084)1.85364936
86Hyporeflexia of lower limbs (HP:0002600)1.84970827
87Bowel incontinence (HP:0002607)1.84291527
88Foot dorsiflexor weakness (HP:0009027)1.84158375
89Supranuclear gaze palsy (HP:0000605)1.84000934
90Enlarged penis (HP:0000040)1.83966274
91Bronchomalacia (HP:0002780)1.83664306
92Atrial fibrillation (HP:0005110)1.82897616
93Pseudobulbar signs (HP:0002200)1.82802374
94Increased nuchal translucency (HP:0010880)1.82461783
95Bowel diverticulosis (HP:0005222)1.80377049
96Obstructive sleep apnea (HP:0002870)1.80229130
97Metaphyseal cupping (HP:0003021)1.79634238
98Calcaneovalgus deformity (HP:0001848)1.77591609
99Fibrous tissue neoplasm (HP:0012316)1.77317861
100Deep venous thrombosis (HP:0002625)1.76923134
101Ulnar deviation of the wrist (HP:0003049)1.75658078
102Genu recurvatum (HP:0002816)1.75568700
103Obsessive-compulsive behavior (HP:0000722)1.75480139
104Vertebral arch anomaly (HP:0008438)1.75337779
105Shoulder girdle muscle weakness (HP:0003547)1.74532059
106Type 1 muscle fiber predominance (HP:0003803)1.74172715
107Focal motor seizures (HP:0011153)1.74055784
108Abnormality of the thoracic spine (HP:0100711)1.73622821
109Exercise-induced myalgia (HP:0003738)1.73041424
110Turricephaly (HP:0000262)1.72201844
111Bladder diverticulum (HP:0000015)1.72177774
112Neoplasm of the heart (HP:0100544)1.72088700
113Megalencephaly (HP:0001355)1.71874108
114Exercise-induced muscle cramps (HP:0003710)1.71721409
115Syringomyelia (HP:0003396)1.71225986
116Spinal cord lesions (HP:0100561)1.71225986
117Spina bifida occulta (HP:0003298)1.70445803
118Supraventricular tachycardia (HP:0004755)1.69842318
119Hypercalcemia (HP:0003072)1.69551603
120Supraventricular arrhythmia (HP:0005115)1.69152569
121Decreased motor nerve conduction velocity (HP:0003431)1.68617701
122Shawl scrotum (HP:0000049)1.67403010
123Overgrowth (HP:0001548)1.66840510
124Achilles tendon contracture (HP:0001771)1.66426302
125Premature rupture of membranes (HP:0001788)1.66253986
126Abnormality of the fingertips (HP:0001211)1.66217325
127Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.65135578
128Difficulty climbing stairs (HP:0003551)1.64678485
129Inappropriate behavior (HP:0000719)1.64372078
130Mildly elevated creatine phosphokinase (HP:0008180)1.64238865
131Abnormality of chromosome segregation (HP:0002916)1.64203347
132Ankyloglossia (HP:0010296)1.63479962
133Segmental peripheral demyelination/remyelination (HP:0003481)1.63357087
134Hammertoe (HP:0001765)1.63336086
135Abnormality of the foot musculature (HP:0001436)1.63325443
136Abnormal large intestine physiology (HP:0012700)1.63158612
137Abnormality of the left ventricular outflow tract (HP:0011103)1.63112190
138Subaortic stenosis (HP:0001682)1.63112190
139Generalized hypotonia (HP:0001290)1.62911921
140Deviation of the hallux (HP:0010051)1.62878639
141Abnormal social behavior (HP:0012433)1.62768397
142Impaired social interactions (HP:0000735)1.62768397
143Trigonocephaly (HP:0000243)1.62095184
144Partial duplication of thumb phalanx (HP:0009944)1.62064528
145Broad metatarsal (HP:0001783)1.61307581
146Short 1st metacarpal (HP:0010034)1.60874580
147Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.60874580
148Poor eye contact (HP:0000817)1.59850654
149Precocious puberty (HP:0000826)1.59816269
150Male infertility (HP:0003251)1.59729585
151Glioma (HP:0009733)1.59130602
152Hallux valgus (HP:0001822)1.58388688
153Hamartoma (HP:0010566)1.57536382
154Spinal rigidity (HP:0003306)1.56535574
155Uterine leiomyosarcoma (HP:0002891)1.56252911
156Leiomyosarcoma (HP:0100243)1.56252911
157Coronal craniosynostosis (HP:0004440)1.56092291
158Intellectual disability, profound (HP:0002187)1.55944362
159Dislocated radial head (HP:0003083)1.55539045
160Drooling (HP:0002307)1.55533138
161Advanced eruption of teeth (HP:0006288)1.55252735
162Broad palm (HP:0001169)1.53982404
163Missing ribs (HP:0000921)1.53866267
164Round ear (HP:0100830)1.53611906
165Arterial tortuosity (HP:0005116)1.52948093

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.55574352
2SMG12.93720280
3SIK12.83176194
4TRIB32.82393747
5PRKD32.78708403
6MAP3K92.73421957
7LATS22.69376718
8PKN22.51976187
9MAP3K42.24335200
10KSR22.21902651
11FGFR42.10166411
12TYRO32.02782523
13EPHA42.02156852
14ICK1.98994494
15PAK61.93512574
16LATS11.86298996
17DAPK21.74867608
18KSR11.73755980
19NEK11.68890936
20CDK121.65748167
21PHKG21.58879327
22PHKG11.58879327
23MAP3K101.58411906
24NTRK21.56109017
25EEF2K1.52716290
26NTRK31.52684671
27TTN1.52052427
28MINK11.45055462
29SIK21.44022516
30PDGFRA1.41060032
31RIPK11.39285189
32ERN11.36003202
33TAOK11.34617043
34MAP3K21.33601189
35IRAK31.32563937
36STK381.32254494
37RET1.27696690
38ALK1.27594315
39DMPK1.25378937
40CAMKK11.23895540
41PRPF4B1.18357257
42MAP3K61.17980903
43SGK31.17131328
44RPS6KB21.12304124
45MAP2K41.08778910
46MAP2K71.08592593
47EPHB21.08098342
48ARAF1.06810107
49LMTK21.05748523
50MAP3K131.03553771
51SGK20.94564158
52ERBB30.93946090
53BRD40.93599846
54STK110.90461278
55EPHA20.90064626
56NTRK10.89601556
57MAP2K30.87229828
58UHMK10.86739805
59PDPK10.84430506
60BRAF0.83915054
61PTK60.83635226
62SGK4940.83506993
63SGK2230.83506993
64PRKCH0.83070653
65CDC70.82134282
66MAPK130.81786995
67CDK50.81028819
68MTOR0.79626374
69BMX0.78938289
70PAK30.77839250
71DDR20.77260721
72MAP2K20.76914074
73SCYL20.75500309
74PDK40.73618500
75PDK30.73618500
76MAP3K110.72902870
77FGFR30.71719092
78CDC42BPA0.70613282
79CDK70.69196822
80CAMK1D0.67739602
81NEK20.67221391
82CDK40.66282793
83RPS6KL10.66086051
84RPS6KC10.66086051
85PRKAA10.65566978
86STK38L0.63814769
87FGFR20.63633318
88CSNK1G20.62650591
89HIPK20.62551556
90MAPK120.62454689
91MARK20.61596802
92CDK150.61422162
93DYRK20.60382852
94MOS0.58012976
95CDK180.57400986
96MAP3K10.55944688
97NEK60.54835150
98CAMK1G0.54776500
99TAOK20.54199517
100PRKD20.53744904
101CDK140.53479416
102RPS6KA20.53212617
103MAPK110.52349714
104IRAK20.51460284
105SGK10.51328648
106MAP3K80.51300925
107ROCK10.51189875
108PINK10.50936176
109CDK11A0.50076699
110PDK10.49947050
111PRKCZ0.49829145
112MAP3K70.49559346
113MAPK100.49535475
114CSNK1D0.49463175
115CHEK20.46982681
116NME20.46917182
117PDGFRB0.46895250
118PAK40.46833181
119PTK20.46435100
120LRRK20.46411230
121DYRK1A0.46409345
122FGFR10.45159087
123PLK20.45074378
124RPS6KA30.44690548
125CDK60.43194745
126TESK10.43162619
127DAPK10.41233136
128CSNK1E0.40938968
129PRKD10.40797190
130RPS6KA60.40391300
131DYRK1B0.40377002
132MAPK80.39180269
133TTK0.38682947
134WNK10.38591190
135RPS6KA10.38242108
136CSNK1A1L0.37445074
137CDK20.36218974
138RPS6KB10.36153565
139RIPK40.34741292
140AKT20.34254818

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.92592388
2Olfactory transduction_Homo sapiens_hsa047401.84482882
3Long-term potentiation_Homo sapiens_hsa047201.84229990
4Endometrial cancer_Homo sapiens_hsa052131.74798082
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.74672920
6Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.71765151
7mTOR signaling pathway_Homo sapiens_hsa041501.70495420
8Glioma_Homo sapiens_hsa052141.60009900
9Acute myeloid leukemia_Homo sapiens_hsa052211.59427319
10Circadian entrainment_Homo sapiens_hsa047131.56783194
11Dorso-ventral axis formation_Homo sapiens_hsa043201.54710960
12Dopaminergic synapse_Homo sapiens_hsa047281.50312705
13Oocyte meiosis_Homo sapiens_hsa041141.48930435
14Axon guidance_Homo sapiens_hsa043601.45641160
15Synaptic vesicle cycle_Homo sapiens_hsa047211.44112974
16Glutamatergic synapse_Homo sapiens_hsa047241.43722279
17GnRH signaling pathway_Homo sapiens_hsa049121.42893408
18Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.41764618
19Dilated cardiomyopathy_Homo sapiens_hsa054141.40745319
20Type II diabetes mellitus_Homo sapiens_hsa049301.39424634
21Cholinergic synapse_Homo sapiens_hsa047251.36679850
22Gap junction_Homo sapiens_hsa045401.36361308
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.34938616
24Estrogen signaling pathway_Homo sapiens_hsa049151.34559309
25Prion diseases_Homo sapiens_hsa050201.34243107
26Oxytocin signaling pathway_Homo sapiens_hsa049211.33525479
27Amphetamine addiction_Homo sapiens_hsa050311.33240764
28Non-small cell lung cancer_Homo sapiens_hsa052231.32510809
29Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.30909349
30Colorectal cancer_Homo sapiens_hsa052101.30750515
31GABAergic synapse_Homo sapiens_hsa047271.28904160
32Hippo signaling pathway_Homo sapiens_hsa043901.28890456
33Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.28564433
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.25370685
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.24851773
36Gastric acid secretion_Homo sapiens_hsa049711.23899422
37Thyroid hormone signaling pathway_Homo sapiens_hsa049191.23844353
38ErbB signaling pathway_Homo sapiens_hsa040121.20846821
39Basal cell carcinoma_Homo sapiens_hsa052171.20624951
40Melanogenesis_Homo sapiens_hsa049161.19946181
41Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.19752320
42Longevity regulating pathway - mammal_Homo sapiens_hsa042111.19656821
43B cell receptor signaling pathway_Homo sapiens_hsa046621.18029715
44Morphine addiction_Homo sapiens_hsa050321.16144297
45Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.16034321
46VEGF signaling pathway_Homo sapiens_hsa043701.15218272
47Renal cell carcinoma_Homo sapiens_hsa052111.15213040
48Nicotine addiction_Homo sapiens_hsa050331.13544207
49Nitrogen metabolism_Homo sapiens_hsa009101.13430535
50Central carbon metabolism in cancer_Homo sapiens_hsa052301.12662981
51Insulin signaling pathway_Homo sapiens_hsa049101.11845295
52Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.11621629
53Chronic myeloid leukemia_Homo sapiens_hsa052201.11606997
54AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.09828135
55Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.09187189
56Insulin secretion_Homo sapiens_hsa049111.09038324
57Salivary secretion_Homo sapiens_hsa049701.07586805
58Neurotrophin signaling pathway_Homo sapiens_hsa047221.07161297
59Adherens junction_Homo sapiens_hsa045201.04649353
60Prostate cancer_Homo sapiens_hsa052151.03549140
61Renin secretion_Homo sapiens_hsa049241.03360647
62Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.03180598
63Wnt signaling pathway_Homo sapiens_hsa043101.02977921
64Hedgehog signaling pathway_Homo sapiens_hsa043401.02895703
65mRNA surveillance pathway_Homo sapiens_hsa030151.02412196
66Tight junction_Homo sapiens_hsa045301.02314181
67Long-term depression_Homo sapiens_hsa047301.02205568
68Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.01911170
69Other glycan degradation_Homo sapiens_hsa005111.01402915
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.00241382
71cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00216095
72Glucagon signaling pathway_Homo sapiens_hsa049220.97147180
73Pentose phosphate pathway_Homo sapiens_hsa000300.95922467
74Cocaine addiction_Homo sapiens_hsa050300.95777823
75cAMP signaling pathway_Homo sapiens_hsa040240.94859403
76Inositol phosphate metabolism_Homo sapiens_hsa005620.94171919
77Lysine degradation_Homo sapiens_hsa003100.92400137
782-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.92371347
79MicroRNAs in cancer_Homo sapiens_hsa052060.92117490
80Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.91941305
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.90033360
82Notch signaling pathway_Homo sapiens_hsa043300.87035016
83AMPK signaling pathway_Homo sapiens_hsa041520.85845046
84Proteoglycans in cancer_Homo sapiens_hsa052050.85111831
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85036652
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.83202372
87Pancreatic cancer_Homo sapiens_hsa052120.83188302
88Choline metabolism in cancer_Homo sapiens_hsa052310.82650888
89Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.82483369
90Bladder cancer_Homo sapiens_hsa052190.82324342
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.81258315
92Biosynthesis of amino acids_Homo sapiens_hsa012300.81000872
93Thyroid hormone synthesis_Homo sapiens_hsa049180.80754095
94Endocytosis_Homo sapiens_hsa041440.80736113
95Prolactin signaling pathway_Homo sapiens_hsa049170.80427277
96MAPK signaling pathway_Homo sapiens_hsa040100.77706174
97Focal adhesion_Homo sapiens_hsa045100.77440474
98Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76403269
99Rap1 signaling pathway_Homo sapiens_hsa040150.76228631
100Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.75261363
101Cardiac muscle contraction_Homo sapiens_hsa042600.74982058
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.74811140
103HIF-1 signaling pathway_Homo sapiens_hsa040660.74475394
104Sphingolipid signaling pathway_Homo sapiens_hsa040710.74320494
105Carbohydrate digestion and absorption_Homo sapiens_hsa049730.73856798
106Thyroid cancer_Homo sapiens_hsa052160.73382414
107Leukocyte transendothelial migration_Homo sapiens_hsa046700.70620991
108Insulin resistance_Homo sapiens_hsa049310.70557386
109FoxO signaling pathway_Homo sapiens_hsa040680.70487414
110Small cell lung cancer_Homo sapiens_hsa052220.70010061
111Calcium signaling pathway_Homo sapiens_hsa040200.69923977
112Regulation of actin cytoskeleton_Homo sapiens_hsa048100.68805529
113Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.67826344
114Ovarian steroidogenesis_Homo sapiens_hsa049130.67678185
115Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.67564440
116Bile secretion_Homo sapiens_hsa049760.66959326
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.66275901
118Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.66161919
119Viral myocarditis_Homo sapiens_hsa054160.65954075
120Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.65723949
121Viral carcinogenesis_Homo sapiens_hsa052030.65054398
122Amoebiasis_Homo sapiens_hsa051460.64852259
123Vascular smooth muscle contraction_Homo sapiens_hsa042700.64543974
124Hepatitis B_Homo sapiens_hsa051610.63857724
125Alcoholism_Homo sapiens_hsa050340.62702251
126Fructose and mannose metabolism_Homo sapiens_hsa000510.62665741
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.57841122
128T cell receptor signaling pathway_Homo sapiens_hsa046600.57413592
129Melanoma_Homo sapiens_hsa052180.55486837
130Hepatitis C_Homo sapiens_hsa051600.55456356

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »