Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 5.82975964 |
2 | chaperone-mediated protein transport (GO:0072321) | 5.65723954 |
3 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.37468553 |
4 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.32311952 |
5 | respiratory electron transport chain (GO:0022904) | 5.18727310 |
6 | ribosomal small subunit biogenesis (GO:0042274) | 5.11905083 |
7 | viral transcription (GO:0019083) | 5.07186809 |
8 | electron transport chain (GO:0022900) | 5.06786941 |
9 | maturation of SSU-rRNA (GO:0030490) | 5.04367575 |
10 | translational termination (GO:0006415) | 4.96123539 |
11 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.87147577 |
12 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.81569174 |
13 | DNA deamination (GO:0045006) | 4.61504577 |
14 | DNA strand elongation (GO:0022616) | 4.60405561 |
15 | protein complex biogenesis (GO:0070271) | 4.44524233 |
16 | telomere maintenance via recombination (GO:0000722) | 4.40085513 |
17 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.38478939 |
18 | regulation of mitochondrial translation (GO:0070129) | 4.38212471 |
19 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.37386559 |
20 | ribosomal large subunit biogenesis (GO:0042273) | 4.36466070 |
21 | translational elongation (GO:0006414) | 4.35383942 |
22 | CENP-A containing nucleosome assembly (GO:0034080) | 4.35240636 |
23 | protein neddylation (GO:0045116) | 4.32541654 |
24 | cotranslational protein targeting to membrane (GO:0006613) | 4.31883228 |
25 | protein targeting to ER (GO:0045047) | 4.27106181 |
26 | chromatin remodeling at centromere (GO:0031055) | 4.23355418 |
27 | DNA replication initiation (GO:0006270) | 4.23321556 |
28 | proteasome assembly (GO:0043248) | 4.15774805 |
29 | mitotic recombination (GO:0006312) | 4.15375404 |
30 | establishment of integrated proviral latency (GO:0075713) | 4.13687746 |
31 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.10856487 |
32 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.10856487 |
33 | NADH dehydrogenase complex assembly (GO:0010257) | 4.10856487 |
34 | translational initiation (GO:0006413) | 4.06328582 |
35 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.05179770 |
36 | protein localization to endoplasmic reticulum (GO:0070972) | 4.03491629 |
37 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.98438127 |
38 | cellular protein complex disassembly (GO:0043624) | 3.92415609 |
39 | viral life cycle (GO:0019058) | 3.90462634 |
40 | telomere maintenance via telomere lengthening (GO:0010833) | 3.89480009 |
41 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.87418033 |
42 | DNA replication checkpoint (GO:0000076) | 3.85121182 |
43 | formation of translation preinitiation complex (GO:0001731) | 3.78054176 |
44 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.77919559 |
45 | DNA unwinding involved in DNA replication (GO:0006268) | 3.77741537 |
46 | kinetochore organization (GO:0051383) | 3.76507343 |
47 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.76320032 |
48 | DNA replication-independent nucleosome organization (GO:0034724) | 3.76320032 |
49 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.75759391 |
50 | protein targeting to mitochondrion (GO:0006626) | 3.75266922 |
51 | respiratory chain complex IV assembly (GO:0008535) | 3.71502818 |
52 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.69702456 |
53 | termination of RNA polymerase III transcription (GO:0006386) | 3.63748941 |
54 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.63748941 |
55 | spliceosomal snRNP assembly (GO:0000387) | 3.63583878 |
56 | translation (GO:0006412) | 3.62094792 |
57 | kinetochore assembly (GO:0051382) | 3.57762189 |
58 | cytochrome complex assembly (GO:0017004) | 3.57333002 |
59 | rRNA processing (GO:0006364) | 3.56651262 |
60 | pseudouridine synthesis (GO:0001522) | 3.54483316 |
61 | mitotic metaphase plate congression (GO:0007080) | 3.52926268 |
62 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.52413975 |
63 | establishment of protein localization to mitochondrion (GO:0072655) | 3.50837575 |
64 | nucleobase biosynthetic process (GO:0046112) | 3.50297777 |
65 | rRNA modification (GO:0000154) | 3.49318097 |
66 | protein localization to mitochondrion (GO:0070585) | 3.49262625 |
67 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.49198765 |
68 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.48239197 |
69 | protein complex disassembly (GO:0043241) | 3.47015974 |
70 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.44520698 |
71 | ATP biosynthetic process (GO:0006754) | 3.44445261 |
72 | rRNA metabolic process (GO:0016072) | 3.43918978 |
73 | spliceosomal complex assembly (GO:0000245) | 3.40587206 |
74 | histone exchange (GO:0043486) | 3.40416835 |
75 | negative regulation of ligase activity (GO:0051352) | 3.40050192 |
76 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.40050192 |
77 | oxidative phosphorylation (GO:0006119) | 3.39970029 |
78 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.36022717 |
79 | * exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.35647293 |
80 | establishment of viral latency (GO:0019043) | 3.34949197 |
81 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.32559025 |
82 | positive regulation of ligase activity (GO:0051351) | 3.32332730 |
83 | macromolecular complex disassembly (GO:0032984) | 3.32204419 |
84 | DNA damage response, detection of DNA damage (GO:0042769) | 3.29678246 |
85 | * nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.28806104 |
86 | purine nucleobase biosynthetic process (GO:0009113) | 3.28627182 |
87 | hydrogen ion transmembrane transport (GO:1902600) | 3.28314665 |
88 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.28250123 |
89 | cellular component biogenesis (GO:0044085) | 3.25071474 |
90 | 7-methylguanosine mRNA capping (GO:0006370) | 3.23825709 |
91 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.23580545 |
92 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.23580545 |
93 | ribosome biogenesis (GO:0042254) | 3.23455165 |
94 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.23103432 |
95 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.22839024 |
96 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.22839024 |
97 | protein localization to kinetochore (GO:0034501) | 3.22454961 |
98 | * nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.22206962 |
99 | RNA capping (GO:0036260) | 3.21193800 |
100 | 7-methylguanosine RNA capping (GO:0009452) | 3.21193800 |
101 | DNA double-strand break processing (GO:0000729) | 3.19729967 |
102 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.18529551 |
103 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.18529551 |
104 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.17843584 |
105 | inner mitochondrial membrane organization (GO:0007007) | 3.17245094 |
106 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.17099887 |
107 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.17099887 |
108 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.17099887 |
109 | ribosome assembly (GO:0042255) | 3.16949439 |
110 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.14372665 |
111 | metaphase plate congression (GO:0051310) | 3.13457335 |
112 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.11983927 |
113 | ATP synthesis coupled proton transport (GO:0015986) | 3.11768008 |
114 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.11768008 |
115 | viral mRNA export from host cell nucleus (GO:0046784) | 3.11467113 |
116 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.10958269 |
117 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.10958269 |
118 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.08103607 |
119 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.08103607 |
120 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.07180892 |
121 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.05971488 |
122 | cell cycle G1/S phase transition (GO:0044843) | 3.05971488 |
123 | * mRNA catabolic process (GO:0006402) | 3.05651258 |
124 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.01068104 |
125 | cullin deneddylation (GO:0010388) | 3.00536794 |
126 | DNA ligation (GO:0006266) | 3.00032898 |
127 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.99863896 |
128 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.99203161 |
129 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.99112316 |
130 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.96614466 |
131 | telomere organization (GO:0032200) | 2.95109350 |
132 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.94878256 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.59757654 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.49691180 |
3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.19617576 |
4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.73351605 |
5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.67998545 |
6 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.63162818 |
7 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.56148975 |
8 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.38537048 |
9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.34306407 |
10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.18146001 |
11 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.15197984 |
12 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.07025180 |
13 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.02714360 |
14 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.00865164 |
15 | * HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.99468177 |
16 | * CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.97613118 |
17 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.94763794 |
18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.82935999 |
19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.82408794 |
20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.59056091 |
21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.56497423 |
22 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.51721854 |
23 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.46591299 |
24 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.34269798 |
25 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.33565564 |
26 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.32785125 |
27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.22077424 |
28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.21613223 |
29 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.19209974 |
30 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.11087669 |
31 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.08129395 |
32 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.06551870 |
33 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.05938182 |
34 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.05915163 |
35 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.96724368 |
36 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.91782090 |
37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.91234049 |
38 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.90970175 |
39 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.89270990 |
40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.87686240 |
41 | * MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.84042255 |
42 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.78096864 |
43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.77167694 |
44 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.75330583 |
45 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.74234703 |
46 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.71957381 |
47 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.71896723 |
48 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.70296190 |
49 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.69864998 |
50 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.69319645 |
51 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.67550749 |
52 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.65365443 |
53 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.50745795 |
54 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.49251550 |
55 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.48669373 |
56 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.46741013 |
57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.41485913 |
58 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.38593996 |
59 | EWS_26573619_Chip-Seq_HEK293_Human | 1.35401194 |
60 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.35395586 |
61 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.29003361 |
62 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.28905832 |
63 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.27865490 |
64 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.24858333 |
65 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.23578736 |
66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.22062221 |
67 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.21606725 |
68 | FUS_26573619_Chip-Seq_HEK293_Human | 1.21006336 |
69 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.18678418 |
70 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.18649622 |
71 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.17818530 |
72 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.16014624 |
73 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.15014283 |
74 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.14873412 |
75 | VDR_22108803_ChIP-Seq_LS180_Human | 1.14822786 |
76 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.14262918 |
77 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.13676792 |
78 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.09639456 |
79 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.08530324 |
80 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.05166032 |
81 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.04110677 |
82 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.03590173 |
83 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.02279772 |
84 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.00978545 |
85 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.99863611 |
86 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.99542436 |
87 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.99033670 |
88 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.96629849 |
89 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.96579695 |
90 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.95406700 |
91 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.94019515 |
92 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.93528290 |
93 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.89361496 |
94 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.84293882 |
95 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.83231182 |
96 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.83109501 |
97 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.82461331 |
98 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.81609907 |
99 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.81248676 |
100 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.78726658 |
101 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.77642546 |
102 | * SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.76560056 |
103 | * ELF5_23300383_ChIP-Seq_T47D_Human | 0.75285992 |
104 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.74991638 |
105 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.74188122 |
106 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.73870011 |
107 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.72549218 |
108 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.72442020 |
109 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.72411453 |
110 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.69587057 |
111 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.69076892 |
112 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.67530188 |
113 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.65962051 |
114 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.65718748 |
115 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.65013012 |
116 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.64867412 |
117 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.64820002 |
118 | MYC_22102868_ChIP-Seq_BL_Human | 0.64487639 |
119 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.64425202 |
120 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.63563067 |
121 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.63274449 |
122 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.63119897 |
123 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.63035699 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.39734664 |
2 | MP0010094_abnormal_chromosome_stability | 4.61226004 |
3 | MP0008057_abnormal_DNA_replication | 4.48770990 |
4 | MP0004957_abnormal_blastocyst_morpholog | 4.34679906 |
5 | MP0003111_abnormal_nucleus_morphology | 3.98900497 |
6 | MP0003077_abnormal_cell_cycle | 3.91419336 |
7 | MP0008058_abnormal_DNA_repair | 3.66281252 |
8 | MP0008007_abnormal_cellular_replicative | 2.87844456 |
9 | MP0008932_abnormal_embryonic_tissue | 2.84841686 |
10 | MP0009379_abnormal_foot_pigmentation | 2.54211179 |
11 | MP0002396_abnormal_hematopoietic_system | 2.45258395 |
12 | MP0003941_abnormal_skin_development | 2.38684340 |
13 | MP0003786_premature_aging | 2.34328658 |
14 | MP0008877_abnormal_DNA_methylation | 2.18239388 |
15 | MP0006072_abnormal_retinal_apoptosis | 2.04503096 |
16 | MP0006292_abnormal_olfactory_placode | 1.93240885 |
17 | MP0003123_paternal_imprinting | 1.85124278 |
18 | MP0003718_maternal_effect | 1.81300155 |
19 | MP0000350_abnormal_cell_proliferation | 1.81252917 |
20 | MP0000490_abnormal_crypts_of | 1.78792402 |
21 | MP0001730_embryonic_growth_arrest | 1.71047620 |
22 | MP0003315_abnormal_perineum_morphology | 1.65734536 |
23 | MP0003136_yellow_coat_color | 1.60562642 |
24 | MP0002837_dystrophic_cardiac_calcinosis | 1.56598328 |
25 | MP0003011_delayed_dark_adaptation | 1.56317770 |
26 | MP0002736_abnormal_nociception_after | 1.52344990 |
27 | MP0002132_abnormal_respiratory_system | 1.48932653 |
28 | MP0000313_abnormal_cell_death | 1.42735829 |
29 | MP0003186_abnormal_redox_activity | 1.39611096 |
30 | MP0009333_abnormal_splenocyte_physiolog | 1.35211273 |
31 | MP0002210_abnormal_sex_determination | 1.35090341 |
32 | MP0008789_abnormal_olfactory_epithelium | 1.33435160 |
33 | MP0002938_white_spotting | 1.32666229 |
34 | MP0005084_abnormal_gallbladder_morpholo | 1.32227932 |
35 | MP0003567_abnormal_fetal_cardiomyocyte | 1.30200869 |
36 | MP0005075_abnormal_melanosome_morpholog | 1.28370579 |
37 | MP0002019_abnormal_tumor_incidence | 1.28028633 |
38 | MP0004133_heterotaxia | 1.27238313 |
39 | MP0004808_abnormal_hematopoietic_stem | 1.25369168 |
40 | MP0003763_abnormal_thymus_physiology | 1.24800260 |
41 | MP0003806_abnormal_nucleotide_metabolis | 1.24126333 |
42 | MP0001697_abnormal_embryo_size | 1.23659944 |
43 | MP0006036_abnormal_mitochondrial_physio | 1.23419007 |
44 | MP0002102_abnormal_ear_morphology | 1.23170331 |
45 | MP0002080_prenatal_lethality | 1.16767004 |
46 | MP0002095_abnormal_skin_pigmentation | 1.15790579 |
47 | MP0001764_abnormal_homeostasis | 1.13801805 |
48 | MP0001529_abnormal_vocalization | 1.13786110 |
49 | MP0002398_abnormal_bone_marrow | 1.12432921 |
50 | MP0001145_abnormal_male_reproductive | 1.12116945 |
51 | MP0005174_abnormal_tail_pigmentation | 1.11868923 |
52 | MP0003121_genomic_imprinting | 1.11756764 |
53 | MP0001293_anophthalmia | 1.11233508 |
54 | MP0005380_embryogenesis_phenotype | 1.11175765 |
55 | MP0001672_abnormal_embryogenesis/_devel | 1.11175765 |
56 | MP0002160_abnormal_reproductive_system | 1.10401326 |
57 | MP0002085_abnormal_embryonic_tissue | 1.09549236 |
58 | MP0001835_abnormal_antigen_presentation | 1.07648705 |
59 | MP0005253_abnormal_eye_physiology | 1.06933996 |
60 | MP0000703_abnormal_thymus_morphology | 1.06716811 |
61 | MP0001853_heart_inflammation | 1.05566922 |
62 | MP0001929_abnormal_gametogenesis | 1.04433929 |
63 | MP0000631_abnormal_neuroendocrine_gland | 1.04193568 |
64 | MP0003195_calcinosis | 1.02317391 |
65 | MP0002722_abnormal_immune_system | 1.01443274 |
66 | MP0005379_endocrine/exocrine_gland_phen | 1.00342253 |
67 | MP0001188_hyperpigmentation | 1.00130506 |
68 | MP0008872_abnormal_physiological_respon | 0.99332855 |
69 | MP0000689_abnormal_spleen_morphology | 0.99317015 |
70 | MP0000372_irregular_coat_pigmentation | 0.99117222 |
71 | MP0000653_abnormal_sex_gland | 0.97918768 |
72 | MP0005389_reproductive_system_phenotype | 0.97781411 |
73 | MP0009697_abnormal_copulation | 0.97696991 |
74 | MP0006035_abnormal_mitochondrial_morpho | 0.94424906 |
75 | MP0005671_abnormal_response_to | 0.93542233 |
76 | MP0002429_abnormal_blood_cell | 0.92562552 |
77 | MP0001986_abnormal_taste_sensitivity | 0.91671799 |
78 | MP0003984_embryonic_growth_retardation | 0.91331299 |
79 | MP0002163_abnormal_gland_morphology | 0.90712213 |
80 | MP0001984_abnormal_olfaction | 0.90707967 |
81 | MP0004147_increased_porphyrin_level | 0.90178156 |
82 | MP0002090_abnormal_vision | 0.88449435 |
83 | MP0003890_abnormal_embryonic-extraembry | 0.88290451 |
84 | MP0002088_abnormal_embryonic_growth/wei | 0.87982803 |
85 | MP0004142_abnormal_muscle_tone | 0.87892716 |
86 | MP0009785_altered_susceptibility_to | 0.87509708 |
87 | MP0001286_abnormal_eye_development | 0.86537701 |
88 | MP0001968_abnormal_touch/_nociception | 0.86460690 |
89 | MP0008995_early_reproductive_senescence | 0.85504049 |
90 | MP0000566_synostosis | 0.85095637 |
91 | MP0008875_abnormal_xenobiotic_pharmacok | 0.84398336 |
92 | MP0000716_abnormal_immune_system | 0.83852051 |
93 | MP0001905_abnormal_dopamine_level | 0.83843689 |
94 | MP0001727_abnormal_embryo_implantation | 0.82397865 |
95 | MP0002084_abnormal_developmental_patter | 0.81999221 |
96 | MP0001119_abnormal_female_reproductive | 0.81174487 |
97 | MP0005332_abnormal_amino_acid | 0.80571429 |
98 | MP0010030_abnormal_orbit_morphology | 0.80526781 |
99 | MP0002148_abnormal_hypersensitivity_rea | 0.79998347 |
100 | MP0005551_abnormal_eye_electrophysiolog | 0.79764295 |
101 | MP0001545_abnormal_hematopoietic_system | 0.78572151 |
102 | MP0005397_hematopoietic_system_phenotyp | 0.78572151 |
103 | MP0004215_abnormal_myocardial_fiber | 0.77372904 |
104 | MP0010307_abnormal_tumor_latency | 0.77296784 |
105 | MP0002420_abnormal_adaptive_immunity | 0.75775443 |
106 | MP0002234_abnormal_pharynx_morphology | 0.75728430 |
107 | MP0002277_abnormal_respiratory_mucosa | 0.74411936 |
108 | MP0001819_abnormal_immune_cell | 0.74101368 |
109 | MP0002233_abnormal_nose_morphology | 0.74085516 |
110 | MP0000358_abnormal_cell_content/ | 0.73769290 |
111 | MP0009046_muscle_twitch | 0.72551349 |
112 | MP0002086_abnormal_extraembryonic_tissu | 0.72110333 |
113 | MP0004197_abnormal_fetal_growth/weight/ | 0.71757970 |
114 | MP0003938_abnormal_ear_development | 0.71569028 |
115 | MP0003698_abnormal_male_reproductive | 0.70030261 |
116 | MP0005395_other_phenotype | 0.69913198 |
117 | MP0005408_hypopigmentation | 0.69618026 |
118 | MP0003937_abnormal_limbs/digits/tail_de | 0.68810942 |
119 | MP0000858_altered_metastatic_potential | 0.68806125 |
120 | MP0005391_vision/eye_phenotype | 0.68478590 |
121 | MP0001881_abnormal_mammary_gland | 0.68262225 |
122 | MP0001800_abnormal_humoral_immune | 0.68117433 |
123 | MP0006054_spinal_hemorrhage | 0.67994716 |
124 | MP0000015_abnormal_ear_pigmentation | 0.67956128 |
125 | MP0002653_abnormal_ependyma_morphology | 0.67543402 |
126 | MP0004145_abnormal_muscle_electrophysio | 0.67354032 |
127 | MP0002638_abnormal_pupillary_reflex | 0.67047483 |
128 | MP0002452_abnormal_antigen_presenting | 0.66937642 |
129 | MP0000647_abnormal_sebaceous_gland | 0.66720829 |
130 | MP0002751_abnormal_autonomic_nervous | 0.66684062 |
131 | MP0002697_abnormal_eye_size | 0.66588210 |
132 | MP0005636_abnormal_mineral_homeostasis | 0.66407554 |
133 | MP0005394_taste/olfaction_phenotype | 0.66314417 |
134 | MP0000049_abnormal_middle_ear | 0.65965887 |
135 | MP0001919_abnormal_reproductive_system | 0.65326521 |
136 | MP0001485_abnormal_pinna_reflex | 0.63639562 |
137 | MP0005409_darkened_coat_color | 0.63286442 |
138 | MP0002723_abnormal_immune_serum | 0.62638734 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.46800898 |
2 | Reticulocytopenia (HP:0001896) | 5.36483652 |
3 | Abnormal number of erythroid precursors (HP:0012131) | 5.17970209 |
4 | Birth length less than 3rd percentile (HP:0003561) | 4.48800268 |
5 | Cerebral edema (HP:0002181) | 3.88962734 |
6 | Aplastic anemia (HP:0001915) | 3.80392482 |
7 | Chromsome breakage (HP:0040012) | 3.63569229 |
8 | Macrocytic anemia (HP:0001972) | 3.58388596 |
9 | Breast hypoplasia (HP:0003187) | 3.54322145 |
10 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.51677684 |
11 | Oral leukoplakia (HP:0002745) | 3.47698894 |
12 | Acute necrotizing encephalopathy (HP:0006965) | 3.46177315 |
13 | Pallor (HP:0000980) | 3.46028295 |
14 | Increased hepatocellular lipid droplets (HP:0006565) | 3.44113674 |
15 | Mitochondrial inheritance (HP:0001427) | 3.35789502 |
16 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.26395583 |
17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.26395583 |
18 | 3-Methylglutaconic aciduria (HP:0003535) | 3.15524319 |
19 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.13808237 |
20 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.10735243 |
21 | Increased CSF lactate (HP:0002490) | 3.06341005 |
22 | Hepatocellular necrosis (HP:0001404) | 3.05981638 |
23 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.03029585 |
24 | Colon cancer (HP:0003003) | 2.96613600 |
25 | Rough bone trabeculation (HP:0100670) | 2.95205098 |
26 | Methylmalonic acidemia (HP:0002912) | 2.93506269 |
27 | Abnormality of the preputium (HP:0100587) | 2.90004973 |
28 | Leukodystrophy (HP:0002415) | 2.89948900 |
29 | Lipid accumulation in hepatocytes (HP:0006561) | 2.89867499 |
30 | Congenital, generalized hypertrichosis (HP:0004540) | 2.88681368 |
31 | Increased muscle lipid content (HP:0009058) | 2.85604879 |
32 | Meckel diverticulum (HP:0002245) | 2.79174269 |
33 | Duplicated collecting system (HP:0000081) | 2.78381639 |
34 | Carpal bone hypoplasia (HP:0001498) | 2.76645208 |
35 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.75925645 |
36 | Increased serum lactate (HP:0002151) | 2.74944476 |
37 | Exertional dyspnea (HP:0002875) | 2.73322125 |
38 | Abnormality of chromosome stability (HP:0003220) | 2.71153789 |
39 | 11 pairs of ribs (HP:0000878) | 2.69776562 |
40 | Patellar aplasia (HP:0006443) | 2.67796354 |
41 | Progressive macrocephaly (HP:0004481) | 2.67276511 |
42 | Methylmalonic aciduria (HP:0012120) | 2.67078531 |
43 | Abnormality of methionine metabolism (HP:0010901) | 2.66212139 |
44 | Abnormality of the ileum (HP:0001549) | 2.65924696 |
45 | Abnormality of renal resorption (HP:0011038) | 2.64519987 |
46 | Premature graying of hair (HP:0002216) | 2.64404664 |
47 | Acute encephalopathy (HP:0006846) | 2.61832917 |
48 | Abnormality of the renal collecting system (HP:0004742) | 2.61369988 |
49 | Cerebral hypomyelination (HP:0006808) | 2.59390575 |
50 | Renal Fanconi syndrome (HP:0001994) | 2.55623159 |
51 | Absent thumb (HP:0009777) | 2.55301511 |
52 | Hepatic necrosis (HP:0002605) | 2.54564132 |
53 | Optic disc pallor (HP:0000543) | 2.52647417 |
54 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.52490142 |
55 | Type I transferrin isoform profile (HP:0003642) | 2.46650840 |
56 | Bone marrow hypocellularity (HP:0005528) | 2.42714124 |
57 | Lethargy (HP:0001254) | 2.42177059 |
58 | Abnormal lung lobation (HP:0002101) | 2.40882032 |
59 | Microretrognathia (HP:0000308) | 2.40036768 |
60 | Microvesicular hepatic steatosis (HP:0001414) | 2.39738826 |
61 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.38249594 |
62 | Selective tooth agenesis (HP:0001592) | 2.36266072 |
63 | Myelodysplasia (HP:0002863) | 2.35303872 |
64 | Pancytopenia (HP:0001876) | 2.35207753 |
65 | Exercise intolerance (HP:0003546) | 2.31789269 |
66 | Increased intramyocellular lipid droplets (HP:0012240) | 2.29942758 |
67 | Abnormality of the labia minora (HP:0012880) | 2.27483603 |
68 | Abnormal trabecular bone morphology (HP:0100671) | 2.25772487 |
69 | Small intestinal stenosis (HP:0012848) | 2.25070045 |
70 | Duodenal stenosis (HP:0100867) | 2.25070045 |
71 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.23614401 |
72 | Muscle fiber atrophy (HP:0100295) | 2.22827888 |
73 | Septo-optic dysplasia (HP:0100842) | 2.22514317 |
74 | Type 2 muscle fiber atrophy (HP:0003554) | 2.21959085 |
75 | Megaloblastic anemia (HP:0001889) | 2.20903084 |
76 | Supernumerary spleens (HP:0009799) | 2.19557371 |
77 | Absent radius (HP:0003974) | 2.19444233 |
78 | Triphalangeal thumb (HP:0001199) | 2.19175158 |
79 | Abnormality of serum amino acid levels (HP:0003112) | 2.17795190 |
80 | Respiratory difficulties (HP:0002880) | 2.15673874 |
81 | IgM deficiency (HP:0002850) | 2.14154115 |
82 | Asplenia (HP:0001746) | 2.13484693 |
83 | Cellular immunodeficiency (HP:0005374) | 2.12837944 |
84 | Medulloblastoma (HP:0002885) | 2.12207531 |
85 | Glycosuria (HP:0003076) | 2.11185605 |
86 | Abnormality of urine glucose concentration (HP:0011016) | 2.11185605 |
87 | Thrombocytosis (HP:0001894) | 2.10373665 |
88 | Cleft eyelid (HP:0000625) | 2.09776481 |
89 | Degeneration of anterior horn cells (HP:0002398) | 2.09547921 |
90 | Abnormality of the anterior horn cell (HP:0006802) | 2.09547921 |
91 | Abnormal number of incisors (HP:0011064) | 2.07230208 |
92 | Abnormal protein glycosylation (HP:0012346) | 2.05198952 |
93 | Abnormal glycosylation (HP:0012345) | 2.05198952 |
94 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.05198952 |
95 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.05198952 |
96 | Horseshoe kidney (HP:0000085) | 2.04299678 |
97 | CNS demyelination (HP:0007305) | 2.04035298 |
98 | Absent forearm bone (HP:0003953) | 2.03764900 |
99 | Aplasia involving forearm bones (HP:0009822) | 2.03764900 |
100 | Hyperphosphaturia (HP:0003109) | 2.02451247 |
101 | Sloping forehead (HP:0000340) | 2.01591017 |
102 | Pancreatic fibrosis (HP:0100732) | 2.00991812 |
103 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.00094619 |
104 | Abnormality of alanine metabolism (HP:0010916) | 2.00094619 |
105 | Hyperalaninemia (HP:0003348) | 2.00094619 |
106 | Reduced antithrombin III activity (HP:0001976) | 1.99786253 |
107 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.97930497 |
108 | Lactic acidosis (HP:0003128) | 1.97528710 |
109 | Abnormality of placental membranes (HP:0011409) | 1.97439561 |
110 | Amniotic constriction ring (HP:0009775) | 1.97439561 |
111 | Stenosis of the external auditory canal (HP:0000402) | 1.95548970 |
112 | Irregular epiphyses (HP:0010582) | 1.95110260 |
113 | Hyperglycinemia (HP:0002154) | 1.94748897 |
114 | X-linked dominant inheritance (HP:0001423) | 1.94161708 |
115 | Abnormality of glycolysis (HP:0004366) | 1.93811240 |
116 | Increased serum pyruvate (HP:0003542) | 1.93811240 |
117 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.92401532 |
118 | Pancreatic cysts (HP:0001737) | 1.91537872 |
119 | Sparse eyelashes (HP:0000653) | 1.90505475 |
120 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.89987220 |
121 | Agnosia (HP:0010524) | 1.89765584 |
122 | Respiratory failure (HP:0002878) | 1.89380417 |
123 | Lymphoma (HP:0002665) | 1.89060411 |
124 | Tracheoesophageal fistula (HP:0002575) | 1.89054130 |
125 | Hypoplasia of the radius (HP:0002984) | 1.88485959 |
126 | Trismus (HP:0000211) | 1.86972246 |
127 | Poor head control (HP:0002421) | 1.85674647 |
128 | Hypoplasia of the pons (HP:0012110) | 1.85638727 |
129 | Neoplasm of the pancreas (HP:0002894) | 1.83050602 |
130 | Abnormality of the duodenum (HP:0002246) | 1.82204108 |
131 | Abnormality of the pons (HP:0007361) | 1.81719428 |
132 | Abnormality of homocysteine metabolism (HP:0010919) | 1.81017907 |
133 | Homocystinuria (HP:0002156) | 1.81017907 |
134 | Glossoptosis (HP:0000162) | 1.79610677 |
135 | Generalized aminoaciduria (HP:0002909) | 1.78881989 |
136 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.77016034 |
137 | Secondary amenorrhea (HP:0000869) | 1.76407755 |
138 | Absent septum pellucidum (HP:0001331) | 1.74891200 |
139 | Multiple enchondromatosis (HP:0005701) | 1.71763671 |
140 | Molar tooth sign on MRI (HP:0002419) | 1.71582486 |
141 | Abnormality of midbrain morphology (HP:0002418) | 1.71582486 |
142 | True hermaphroditism (HP:0010459) | 1.68984009 |
143 | Pendular nystagmus (HP:0012043) | 1.68615638 |
Rank | Gene Set | Z-score |
---|---|---|
1 | VRK2 | 4.79510048 |
2 | BUB1 | 4.70882043 |
3 | WEE1 | 4.41718578 |
4 | STK16 | 3.42566333 |
5 | CDC7 | 3.32402661 |
6 | EIF2AK1 | 3.22325745 |
7 | SRPK1 | 3.16345462 |
8 | VRK1 | 3.01386864 |
9 | NME2 | 2.59245727 |
10 | PLK4 | 2.49853482 |
11 | BRSK2 | 2.31686266 |
12 | MKNK1 | 2.14174493 |
13 | EIF2AK3 | 2.13846652 |
14 | TAF1 | 1.98816595 |
15 | TLK1 | 1.97472203 |
16 | CCNB1 | 1.97077120 |
17 | NUAK1 | 1.92744154 |
18 | TTK | 1.79060194 |
19 | PLK1 | 1.74230536 |
20 | NEK2 | 1.67252637 |
21 | TSSK6 | 1.67235435 |
22 | PBK | 1.59481004 |
23 | ACVR1B | 1.59303672 |
24 | AURKB | 1.49431041 |
25 | MKNK2 | 1.48603944 |
26 | DYRK3 | 1.48027509 |
27 | CDK7 | 1.45126800 |
28 | ATR | 1.44246558 |
29 | MST4 | 1.43592318 |
30 | PIM2 | 1.42099892 |
31 | PASK | 1.42032643 |
32 | WNK3 | 1.41080000 |
33 | RPS6KB2 | 1.37090730 |
34 | PLK3 | 1.36363140 |
35 | NME1 | 1.34903797 |
36 | TESK2 | 1.33504203 |
37 | BRSK1 | 1.32967837 |
38 | ZAK | 1.29918279 |
39 | CDK8 | 1.22498326 |
40 | MAP4K2 | 1.21162086 |
41 | CHEK2 | 1.17095365 |
42 | AURKA | 1.15760368 |
43 | TRIM28 | 1.15228998 |
44 | STK4 | 1.10560027 |
45 | NEK1 | 1.08137424 |
46 | EIF2AK2 | 1.03802418 |
47 | CDK19 | 1.03223239 |
48 | TEC | 1.00709842 |
49 | PDK2 | 0.97926184 |
50 | CSNK1G1 | 0.95338533 |
51 | RPS6KA4 | 0.94805687 |
52 | TNIK | 0.91517749 |
53 | IRAK4 | 0.90931787 |
54 | PAK4 | 0.85261249 |
55 | MUSK | 0.84894994 |
56 | CHEK1 | 0.84420771 |
57 | RPS6KA5 | 0.84063373 |
58 | FLT3 | 0.82784316 |
59 | KDR | 0.82643483 |
60 | DYRK2 | 0.82414439 |
61 | CSNK2A1 | 0.81720200 |
62 | TGFBR1 | 0.77140494 |
63 | CSNK2A2 | 0.76504395 |
64 | MAP3K8 | 0.76276621 |
65 | CSNK1G2 | 0.76244006 |
66 | OXSR1 | 0.75726312 |
67 | GRK1 | 0.74562237 |
68 | EPHA2 | 0.74461422 |
69 | PLK2 | 0.73284232 |
70 | KIT | 0.71538590 |
71 | PIM1 | 0.68336502 |
72 | YES1 | 0.67394199 |
73 | CDK4 | 0.67038937 |
74 | BRAF | 0.65916435 |
75 | PNCK | 0.63722878 |
76 | CSNK1A1L | 0.63449245 |
77 | IRAK3 | 0.63447906 |
78 | FRK | 0.61943300 |
79 | ATM | 0.61718249 |
80 | CLK1 | 0.60387190 |
81 | BTK | 0.58482110 |
82 | PAK1 | 0.55812837 |
83 | SCYL2 | 0.54606528 |
84 | CDK2 | 0.54307678 |
85 | MAP2K7 | 0.51735533 |
86 | CSNK1E | 0.50687305 |
87 | ADRBK2 | 0.50407975 |
88 | TXK | 0.50018132 |
89 | INSRR | 0.48973284 |
90 | STK10 | 0.48707832 |
91 | MAP3K12 | 0.48484614 |
92 | STK38L | 0.46133384 |
93 | CDK1 | 0.45981782 |
94 | DAPK1 | 0.45752233 |
95 | ILK | 0.45308052 |
96 | LIMK1 | 0.45145198 |
97 | LRRK2 | 0.44683917 |
98 | MYLK | 0.44358510 |
99 | BRD4 | 0.44320339 |
100 | MELK | 0.43920856 |
101 | PRKCI | 0.42576946 |
102 | MAP4K1 | 0.42544627 |
103 | STK3 | 0.42265282 |
104 | ERBB3 | 0.42050683 |
105 | PRKCG | 0.41913058 |
106 | BCR | 0.41469487 |
107 | CSF1R | 0.40704187 |
108 | ABL2 | 0.39203242 |
109 | DAPK3 | 0.39165393 |
110 | MAP3K4 | 0.39123753 |
111 | IKBKB | 0.38473970 |
112 | CDK3 | 0.38366807 |
113 | TESK1 | 0.38021215 |
114 | ARAF | 0.35450712 |
115 | ALK | 0.35306918 |
116 | BMPR1B | 0.35283635 |
117 | LYN | 0.34871856 |
118 | CSNK1G3 | 0.33273825 |
119 | MAP3K11 | 0.32003411 |
120 | CSNK1A1 | 0.30417494 |
121 | PINK1 | 0.28809930 |
122 | BLK | 0.28254204 |
123 | WNK4 | 0.27863954 |
124 | STK39 | 0.27794820 |
125 | MAPKAPK5 | 0.27779046 |
126 | NEK6 | 0.26856213 |
127 | ERBB4 | 0.26833711 |
128 | OBSCN | 0.25806533 |
129 | GRK7 | 0.24396356 |
130 | PRKDC | 0.23604501 |
131 | PRKACB | 0.23437190 |
132 | AKT2 | 0.23142772 |
133 | NLK | 0.22991635 |
134 | BCKDK | 0.22587164 |
135 | TAOK2 | 0.22269548 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 4.81908581 |
2 | DNA replication_Homo sapiens_hsa03030 | 4.73764477 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 4.13544393 |
4 | Proteasome_Homo sapiens_hsa03050 | 4.05374747 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.71407434 |
6 | Homologous recombination_Homo sapiens_hsa03440 | 3.22289027 |
7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.16437134 |
8 | * Spliceosome_Homo sapiens_hsa03040 | 3.16141404 |
9 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.85956604 |
10 | Base excision repair_Homo sapiens_hsa03410 | 2.75735821 |
11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.72803199 |
12 | RNA transport_Homo sapiens_hsa03013 | 2.45463231 |
13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.26627267 |
14 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.20606245 |
15 | Cell cycle_Homo sapiens_hsa04110 | 2.12672674 |
16 | Basal transcription factors_Homo sapiens_hsa03022 | 2.04268575 |
17 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.02360623 |
18 | Parkinsons disease_Homo sapiens_hsa05012 | 1.99846840 |
19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.87720726 |
20 | Protein export_Homo sapiens_hsa03060 | 1.84698064 |
21 | * RNA degradation_Homo sapiens_hsa03018 | 1.79890295 |
22 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.73649335 |
23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.69161559 |
24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.66761462 |
25 | Purine metabolism_Homo sapiens_hsa00230 | 1.50003164 |
26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.30497340 |
27 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.26791665 |
28 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.20321399 |
29 | Alzheimers disease_Homo sapiens_hsa05010 | 1.18988328 |
30 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.18920396 |
31 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.18081058 |
32 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.17517705 |
33 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.14099177 |
34 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.10741044 |
35 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.06379352 |
36 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.06304415 |
37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.94680365 |
38 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.81658396 |
39 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.81062410 |
40 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.73994772 |
41 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.72912199 |
42 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.72557809 |
43 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.69696537 |
44 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.69653603 |
45 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.68108621 |
46 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.67147337 |
47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.66232228 |
48 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.64339123 |
49 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.63529391 |
50 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.62579220 |
51 | Peroxisome_Homo sapiens_hsa04146 | 0.60351134 |
52 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.59859994 |
53 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59115324 |
54 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.58187488 |
55 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.56052074 |
56 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.55781588 |
57 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.55494261 |
58 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55356596 |
59 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.54913607 |
60 | Allograft rejection_Homo sapiens_hsa05330 | 0.54179955 |
61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51269161 |
62 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.50926411 |
63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.49096871 |
64 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.48966025 |
65 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.47850952 |
66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.46541476 |
67 | Alcoholism_Homo sapiens_hsa05034 | 0.46484347 |
68 | Legionellosis_Homo sapiens_hsa05134 | 0.44003658 |
69 | Phototransduction_Homo sapiens_hsa04744 | 0.43717796 |
70 | Sulfur relay system_Homo sapiens_hsa04122 | 0.43643942 |
71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.43273841 |
72 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42963676 |
73 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42752014 |
74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.42685380 |
75 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.42601696 |
76 | HTLV-I infection_Homo sapiens_hsa05166 | 0.41575037 |
77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.41501209 |
78 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.37867733 |
79 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.36504541 |
80 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.36448722 |
81 | Retinol metabolism_Homo sapiens_hsa00830 | 0.35622066 |
82 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.35344632 |
83 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.35238061 |
84 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.34481084 |
85 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.33885967 |
86 | Asthma_Homo sapiens_hsa05310 | 0.33034346 |
87 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.32902285 |
88 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.31564436 |
89 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.31346307 |
90 | Measles_Homo sapiens_hsa05162 | 0.31225815 |
91 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.30835748 |
92 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.30633055 |
93 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.30558060 |
94 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.29396665 |
95 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.27933035 |
96 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.27231091 |
97 | Shigellosis_Homo sapiens_hsa05131 | 0.26099427 |
98 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.26003736 |
99 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.25116493 |
100 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.24989892 |
101 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.22281711 |
102 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.21932932 |
103 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.21342742 |
104 | Apoptosis_Homo sapiens_hsa04210 | 0.21288819 |
105 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.21097202 |
106 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.20425802 |
107 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.19469479 |
108 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.17518322 |
109 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.15907002 |
110 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.15374884 |
111 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.15334111 |
112 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.14205341 |
113 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.13998352 |
114 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.13981002 |
115 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.13960789 |
116 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.13643035 |
117 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.13339012 |
118 | Hepatitis B_Homo sapiens_hsa05161 | 0.12812523 |
119 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.12367714 |
120 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.12180962 |
121 | Influenza A_Homo sapiens_hsa05164 | 0.12035207 |
122 | Thyroid cancer_Homo sapiens_hsa05216 | 0.10905427 |
123 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.10680303 |
124 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.09167392 |
125 | Mineral absorption_Homo sapiens_hsa04978 | 0.08106413 |
126 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.07919574 |
127 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.07787573 |
128 | Olfactory transduction_Homo sapiens_hsa04740 | 0.07402880 |
129 | Pathways in cancer_Homo sapiens_hsa05200 | 0.07320637 |
130 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.07038363 |
131 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.06860816 |
132 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.06802859 |
133 | Carbon metabolism_Homo sapiens_hsa01200 | 0.06164749 |
134 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.06017413 |
135 | Colorectal cancer_Homo sapiens_hsa05210 | 0.04797117 |
136 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.04071804 |
137 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.03347506 |
138 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.03271160 |