Rank | Gene Set | Z-score |
---|---|---|
1 | response to xenobiotic stimulus (GO:0009410) | 7.00103926 |
2 | nuclear pore complex assembly (GO:0051292) | 6.76899538 |
3 | cysteine metabolic process (GO:0006534) | 6.72649588 |
4 | response to nitrosative stress (GO:0051409) | 6.41621353 |
5 | mitotic sister chromatid cohesion (GO:0007064) | 6.18000674 |
6 | nuclear pore organization (GO:0006999) | 6.11065055 |
7 | definitive hemopoiesis (GO:0060216) | 5.06305158 |
8 | monoubiquitinated protein deubiquitination (GO:0035520) | 5.00782640 |
9 | heparin biosynthetic process (GO:0030210) | 4.85489848 |
10 | heparin metabolic process (GO:0030202) | 4.85489848 |
11 | regulation of RNA export from nucleus (GO:0046831) | 4.75138750 |
12 | pore complex assembly (GO:0046931) | 4.72499081 |
13 | negative regulation of T cell differentiation in thymus (GO:0033085) | 4.68775105 |
14 | regulation of DNA endoreduplication (GO:0032875) | 4.47107640 |
15 | intra-S DNA damage checkpoint (GO:0031573) | 4.45682200 |
16 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.41174244 |
17 | viral mRNA export from host cell nucleus (GO:0046784) | 4.25988298 |
18 | regulation of nucleobase-containing compound transport (GO:0032239) | 4.22142707 |
19 | sister chromatid segregation (GO:0000819) | 4.21512805 |
20 | regulation of translational fidelity (GO:0006450) | 4.14126859 |
21 | DNA unwinding involved in DNA replication (GO:0006268) | 4.08997945 |
22 | mitotic chromosome condensation (GO:0007076) | 4.03831479 |
23 | COPI coating of Golgi vesicle (GO:0048205) | 3.93899016 |
24 | Golgi transport vesicle coating (GO:0048200) | 3.93899016 |
25 | protein K11-linked deubiquitination (GO:0035871) | 3.93078624 |
26 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.90271308 |
27 | L-ascorbic acid metabolic process (GO:0019852) | 3.89351704 |
28 | negative regulation of DNA recombination (GO:0045910) | 3.80568503 |
29 | mitotic nuclear envelope disassembly (GO:0007077) | 3.78653494 |
30 | nuclear envelope disassembly (GO:0051081) | 3.77037135 |
31 | membrane disassembly (GO:0030397) | 3.77037135 |
32 | peptidyl-lysine dimethylation (GO:0018027) | 3.75664292 |
33 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.75403045 |
34 | non-recombinational repair (GO:0000726) | 3.75403045 |
35 | ribosome assembly (GO:0042255) | 3.73977853 |
36 | S-adenosylmethionine metabolic process (GO:0046500) | 3.73244101 |
37 | NLS-bearing protein import into nucleus (GO:0006607) | 3.70053882 |
38 | regulation of translational termination (GO:0006449) | 3.67902493 |
39 | regulation of histone H3-K9 methylation (GO:0051570) | 3.65399300 |
40 | acrosome assembly (GO:0001675) | 3.61978205 |
41 | protein localization to kinetochore (GO:0034501) | 3.54974645 |
42 | regulation of protein polyubiquitination (GO:1902914) | 3.52228891 |
43 | chromosome condensation (GO:0030261) | 3.48116308 |
44 | nucleus organization (GO:0006997) | 3.46440610 |
45 | pre-miRNA processing (GO:0031054) | 3.46007912 |
46 | centriole replication (GO:0007099) | 3.43338900 |
47 | mitotic sister chromatid segregation (GO:0000070) | 3.43153620 |
48 | spindle assembly involved in mitosis (GO:0090307) | 3.41728099 |
49 | negative regulation of histone methylation (GO:0031061) | 3.37766706 |
50 | regulation of centriole replication (GO:0046599) | 3.35011694 |
51 | response to pheromone (GO:0019236) | 3.34865959 |
52 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.29392034 |
53 | protein targeting to Golgi (GO:0000042) | 3.26284197 |
54 | DNA geometric change (GO:0032392) | 3.23560934 |
55 | DNA duplex unwinding (GO:0032508) | 3.21907238 |
56 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.21146732 |
57 | regulation of mitotic spindle organization (GO:0060236) | 3.20120080 |
58 | microtubule cytoskeleton organization involved in mitosis (GO:1902850) | 3.18552672 |
59 | cytoplasmic mRNA processing body assembly (GO:0033962) | 3.17605364 |
60 | establishment of protein localization to Golgi (GO:0072600) | 3.16995322 |
61 | chromatin assembly (GO:0031497) | 3.15952983 |
62 | dosage compensation (GO:0007549) | 3.15145676 |
63 | regulation of spindle organization (GO:0090224) | 3.15016608 |
64 | microtubule polymerization or depolymerization (GO:0031109) | 3.14182391 |
65 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.13279134 |
66 | regulation of mitochondrial depolarization (GO:0051900) | 3.12726185 |
67 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.10224490 |
68 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.10095900 |
69 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.10095900 |
70 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.10095900 |
71 | regulation of meiosis I (GO:0060631) | 3.09776978 |
72 | protein localization to chromosome, centromeric region (GO:0071459) | 3.08542063 |
73 | positive regulation of chromosome segregation (GO:0051984) | 3.08191776 |
74 | gene silencing by RNA (GO:0031047) | 3.07946013 |
75 | regulation of centrosome duplication (GO:0010824) | 3.05738271 |
76 | DNA packaging (GO:0006323) | 3.04378571 |
77 | rRNA methylation (GO:0031167) | 3.03945996 |
78 | sister chromatid cohesion (GO:0007062) | 3.03071378 |
79 | regulation of translational elongation (GO:0006448) | 3.02071128 |
80 | positive regulation of histone deacetylation (GO:0031065) | 2.99421720 |
81 | chaperone-mediated protein complex assembly (GO:0051131) | 2.98993159 |
82 | histone mRNA catabolic process (GO:0071044) | 2.96944426 |
83 | translesion synthesis (GO:0019985) | 2.96554189 |
84 | sperm motility (GO:0030317) | 2.95731609 |
85 | musculoskeletal movement (GO:0050881) | 2.93842672 |
86 | multicellular organismal movement (GO:0050879) | 2.93842672 |
87 | protein export from nucleus (GO:0006611) | 2.92690997 |
88 | regulation of sister chromatid cohesion (GO:0007063) | 2.92246442 |
89 | zinc ion transport (GO:0006829) | 2.89621886 |
90 | nuclear envelope organization (GO:0006998) | 2.89509281 |
91 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.87764646 |
92 | isotype switching (GO:0045190) | 2.87764646 |
93 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.87764646 |
94 | regulation of centrosome cycle (GO:0046605) | 2.86618392 |
95 | ncRNA catabolic process (GO:0034661) | 2.86037685 |
96 | myelin assembly (GO:0032288) | 2.83128442 |
97 | replication fork processing (GO:0031297) | 2.82998303 |
98 | DNA conformation change (GO:0071103) | 2.81297686 |
99 | cytoskeleton-dependent cytokinesis (GO:0061640) | 2.80315693 |
100 | protein localization to Golgi apparatus (GO:0034067) | 2.79231721 |
101 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.78082530 |
102 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.78082530 |
103 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.77664023 |
104 | gene silencing (GO:0016458) | 2.76059764 |
105 | mitotic cytokinesis (GO:0000281) | 2.75885121 |
106 | cellular response to glucose starvation (GO:0042149) | 2.75160387 |
107 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 2.74948697 |
108 | establishment of mitotic spindle localization (GO:0040001) | 2.74545265 |
109 | regulation of thymocyte apoptotic process (GO:0070243) | 2.72513963 |
110 | mRNA stabilization (GO:0048255) | 2.71021188 |
111 | RNA stabilization (GO:0043489) | 2.71021188 |
112 | microtubule anchoring (GO:0034453) | 2.69729258 |
113 | regulation of intracellular estrogen receptor signaling pathway (GO:0033146) | 2.69553475 |
114 | COPII vesicle coating (GO:0048208) | 2.69540513 |
115 | intestinal epithelial cell development (GO:0060576) | 2.69203139 |
116 | histone H2A monoubiquitination (GO:0035518) | 2.66958038 |
117 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.64735757 |
118 | mitotic spindle organization (GO:0007052) | 2.64648622 |
119 | negative regulation of DNA repair (GO:0045738) | 2.64395332 |
120 | meiotic cell cycle (GO:0051321) | 2.63338189 |
121 | interkinetic nuclear migration (GO:0022027) | 2.62802767 |
122 | regulation of T cell differentiation in thymus (GO:0033081) | 2.62214432 |
123 | microtubule depolymerization (GO:0007019) | 2.61813063 |
124 | negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) | 2.61396700 |
125 | establishment of nucleus localization (GO:0040023) | 2.60844962 |
126 | establishment of mitotic spindle orientation (GO:0000132) | 2.60118486 |
127 | spermatid nucleus differentiation (GO:0007289) | 2.59317953 |
128 | protein localization to endosome (GO:0036010) | 2.58346662 |
129 | lipid translocation (GO:0034204) | 2.58181383 |
130 | phospholipid translocation (GO:0045332) | 2.58181383 |
131 | Golgi to endosome transport (GO:0006895) | 2.58002237 |
132 | histone H3-K9 methylation (GO:0051567) | 2.57782725 |
133 | regulation of establishment of cell polarity (GO:2000114) | 2.57669080 |
134 | histone phosphorylation (GO:0016572) | 2.57096971 |
135 | positive regulation of T cell apoptotic process (GO:0070234) | 2.56385727 |
136 | genitalia morphogenesis (GO:0035112) | 2.55634920 |
137 | inositol phosphate catabolic process (GO:0071545) | 2.53776620 |
138 | chromatin silencing (GO:0006342) | 2.53715046 |
139 | vesicle coating (GO:0006901) | 2.52920009 |
140 | histone-serine phosphorylation (GO:0035404) | 2.52809978 |
141 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.52618804 |
142 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.52453421 |
143 | response to arsenic-containing substance (GO:0046685) | 2.52333787 |
144 | positive regulation of cell cycle checkpoint (GO:1901978) | 2.52237155 |
145 | proteasome assembly (GO:0043248) | 2.51633849 |
146 | DNA topological change (GO:0006265) | 2.51461234 |
147 | regulation of DNA damage checkpoint (GO:2000001) | 2.50354529 |
148 | corticosteroid receptor signaling pathway (GO:0031958) | 2.49857883 |
149 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.49179163 |
150 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.48831121 |
151 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.48831121 |
152 | regulation of sister chromatid segregation (GO:0033045) | 2.48831121 |
153 | response to epidermal growth factor (GO:0070849) | 2.48524069 |
154 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.48260792 |
155 | protein K48-linked deubiquitination (GO:0071108) | 2.47912530 |
156 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.47522834 |
157 | peptidyl-threonine phosphorylation (GO:0018107) | 2.47222465 |
158 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.46774643 |
159 | positive regulation of T cell differentiation in thymus (GO:0033089) | 2.45465072 |
160 | N-terminal protein amino acid acetylation (GO:0006474) | 2.45365592 |
161 | prenylation (GO:0097354) | 2.45279132 |
162 | protein prenylation (GO:0018342) | 2.45279132 |
163 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.41264974 |
164 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.41264974 |
165 | neural tube formation (GO:0001841) | 2.40708722 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.30807725 |
2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 6.30743952 |
3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.35430758 |
4 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.08197450 |
5 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.98310265 |
6 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 3.74970790 |
7 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.37011300 |
8 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.73737140 |
9 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.72073358 |
10 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.66186414 |
11 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.61216520 |
12 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.45886374 |
13 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.32688603 |
14 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.30199146 |
15 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.29481205 |
16 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.24453930 |
17 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.17377226 |
18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.07136654 |
19 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.02332350 |
20 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.94753597 |
21 | P300_19829295_ChIP-Seq_ESCs_Human | 1.92283917 |
22 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.74013512 |
23 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.72425612 |
24 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.71314130 |
25 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.67311740 |
26 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.65448240 |
27 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.65324726 |
28 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.61086452 |
29 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.59547117 |
30 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.58328951 |
31 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.56124536 |
32 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.56124536 |
33 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.55359907 |
34 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.54037079 |
35 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.52427685 |
36 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.49478740 |
37 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.46368133 |
38 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.45832184 |
39 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.45423935 |
40 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.44439930 |
41 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.43361032 |
42 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.43262258 |
43 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.42975854 |
44 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.42151623 |
45 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.40385874 |
46 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.40268532 |
47 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.38531971 |
48 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.36873124 |
49 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.36648530 |
50 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.35623967 |
51 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.35623967 |
52 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.34449330 |
53 | MYC_22102868_ChIP-Seq_BL_Human | 1.33252506 |
54 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.32956739 |
55 | VDR_22108803_ChIP-Seq_LS180_Human | 1.32571698 |
56 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.32047946 |
57 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.30515618 |
58 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.30387760 |
59 | TP53_16413492_ChIP-PET_HCT116_Human | 1.28791865 |
60 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.28703375 |
61 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.27007318 |
62 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.25051877 |
63 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.24337534 |
64 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.23339924 |
65 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.23233692 |
66 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.23028670 |
67 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.20660943 |
68 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.20585167 |
69 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.19469572 |
70 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.18908644 |
71 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.18325781 |
72 | EWS_26573619_Chip-Seq_HEK293_Human | 1.18250178 |
73 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17566571 |
74 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.16466164 |
75 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.16027307 |
76 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.15852120 |
77 | FUS_26573619_Chip-Seq_HEK293_Human | 1.15765951 |
78 | AR_25329375_ChIP-Seq_VCAP_Human | 1.13471112 |
79 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.12951762 |
80 | STAT3_23295773_ChIP-Seq_U87_Human | 1.12235217 |
81 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.11412329 |
82 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.11284506 |
83 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.11164037 |
84 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.09850042 |
85 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.08213307 |
86 | CJUN_26792858_Chip-Seq_BT549_Human | 1.07476942 |
87 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.07437239 |
88 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.07437239 |
89 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.06489972 |
90 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.05803592 |
91 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05231835 |
92 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.04767984 |
93 | TCF4_23295773_ChIP-Seq_U87_Human | 1.04106007 |
94 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.03361359 |
95 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.02794666 |
96 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.02582885 |
97 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.01979190 |
98 | GATA1_22025678_ChIP-Seq_K562_Human | 1.01728286 |
99 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.01426201 |
100 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.00910047 |
101 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.00710862 |
102 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.00021520 |
103 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.99439794 |
104 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.97767129 |
105 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.97388767 |
106 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.96826228 |
107 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.96685837 |
108 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.96542783 |
109 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.96489232 |
110 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.96383094 |
111 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.96007895 |
112 | NFYB_21822215_ChIP-Seq_K562_Human | 0.95981929 |
113 | JUN_21703547_ChIP-Seq_K562_Human | 0.95788504 |
114 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.95766628 |
115 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.95764830 |
116 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.95600943 |
117 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.92336677 |
118 | MYB_26560356_Chip-Seq_TH1_Human | 0.89264179 |
119 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.88643396 |
120 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.88508510 |
121 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.88349460 |
122 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.86071834 |
123 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.84726338 |
124 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.84318604 |
125 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.83678796 |
126 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.82361346 |
127 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.82301393 |
128 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.81843705 |
129 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.80578266 |
130 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.80455315 |
131 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.77834280 |
132 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.77115727 |
133 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.77062754 |
134 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.74971897 |
135 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.74856836 |
136 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.74770526 |
137 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.74406145 |
138 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.73812530 |
139 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.73469117 |
140 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.72514303 |
141 | MYB_26560356_Chip-Seq_TH2_Human | 0.70860936 |
142 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.70527239 |
143 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.69867172 |
144 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.69435265 |
145 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.68834385 |
146 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.68793783 |
147 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.68591820 |
148 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.68280889 |
149 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.67532698 |
150 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.67303117 |
151 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.66979932 |
152 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.66898726 |
153 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.66459967 |
154 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.66344464 |
155 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.66231017 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000569_abnormal_digit_pigmentation | 5.54043031 |
2 | MP0005423_abnormal_somatic_nervous | 3.66782104 |
3 | MP0010352_gastrointestinal_tract_polyps | 3.24517473 |
4 | MP0010094_abnormal_chromosome_stability | 3.10715074 |
5 | MP0003705_abnormal_hypodermis_morpholog | 2.95136207 |
6 | MP0010307_abnormal_tumor_latency | 2.92529701 |
7 | MP0008057_abnormal_DNA_replication | 2.84933892 |
8 | MP0003300_gastrointestinal_ulcer | 2.73422998 |
9 | MP0008877_abnormal_DNA_methylation | 2.69803174 |
10 | MP0010234_abnormal_vibrissa_follicle | 2.54616029 |
11 | MP0005410_abnormal_fertilization | 2.29158537 |
12 | MP0002877_abnormal_melanocyte_morpholog | 2.27437683 |
13 | MP0001730_embryonic_growth_arrest | 2.25090814 |
14 | MP0003111_abnormal_nucleus_morphology | 2.19443603 |
15 | MP0005076_abnormal_cell_differentiation | 2.17980940 |
16 | MP0003950_abnormal_plasma_membrane | 2.17932078 |
17 | MP0003221_abnormal_cardiomyocyte_apopto | 2.13746723 |
18 | MP0003121_genomic_imprinting | 2.09810892 |
19 | MP0004084_abnormal_cardiac_muscle | 2.09673153 |
20 | MP0004957_abnormal_blastocyst_morpholog | 2.03421722 |
21 | MP0003123_paternal_imprinting | 1.98791144 |
22 | MP0003077_abnormal_cell_cycle | 1.94264903 |
23 | MP0003693_abnormal_embryo_hatching | 1.91968780 |
24 | MP0003787_abnormal_imprinting | 1.90417249 |
25 | MP0004264_abnormal_extraembryonic_tissu | 1.86856963 |
26 | MP0008438_abnormal_cutaneous_collagen | 1.85528579 |
27 | MP0005623_abnormal_meninges_morphology | 1.83692889 |
28 | MP0000537_abnormal_urethra_morphology | 1.81164964 |
29 | MP0003091_abnormal_cell_migration | 1.78450486 |
30 | MP0003943_abnormal_hepatobiliary_system | 1.76671921 |
31 | MP0001299_abnormal_eye_distance/ | 1.76583263 |
32 | MP0004197_abnormal_fetal_growth/weight/ | 1.72576994 |
33 | MP0003984_embryonic_growth_retardation | 1.63945152 |
34 | MP0002088_abnormal_embryonic_growth/wei | 1.63586357 |
35 | MP0005380_embryogenesis_phenotype | 1.61312931 |
36 | MP0001672_abnormal_embryogenesis/_devel | 1.61312931 |
37 | MP0002086_abnormal_extraembryonic_tissu | 1.57763939 |
38 | MP0009780_abnormal_chondrocyte_physiolo | 1.57703365 |
39 | MP0002084_abnormal_developmental_patter | 1.52413457 |
40 | MP0004808_abnormal_hematopoietic_stem | 1.51767770 |
41 | MP0002396_abnormal_hematopoietic_system | 1.51603315 |
42 | MP0000350_abnormal_cell_proliferation | 1.49676196 |
43 | MP0001697_abnormal_embryo_size | 1.45096848 |
44 | MP0002102_abnormal_ear_morphology | 1.43597146 |
45 | MP0004233_abnormal_muscle_weight | 1.41803824 |
46 | MP0002254_reproductive_system_inflammat | 1.39400066 |
47 | MP0003890_abnormal_embryonic-extraembry | 1.39116125 |
48 | MP0003566_abnormal_cell_adhesion | 1.38960574 |
49 | MP0009703_decreased_birth_body | 1.37865034 |
50 | MP0001661_extended_life_span | 1.34765915 |
51 | MP0003718_maternal_effect | 1.33659787 |
52 | MP0004185_abnormal_adipocyte_glucose | 1.33626884 |
53 | MP0004134_abnormal_chest_morphology | 1.33206371 |
54 | MP0001929_abnormal_gametogenesis | 1.31643369 |
55 | MP0008007_abnormal_cellular_replicative | 1.28450050 |
56 | MP0003632_abnormal_nervous_system | 1.24539877 |
57 | MP0004145_abnormal_muscle_electrophysio | 1.24419841 |
58 | MP0002085_abnormal_embryonic_tissue | 1.21916581 |
59 | MP0004484_altered_response_of | 1.21915493 |
60 | MP0003763_abnormal_thymus_physiology | 1.21402469 |
61 | MP0003045_fibrosis | 1.19724992 |
62 | MP0003698_abnormal_male_reproductive | 1.18667028 |
63 | MP0006054_spinal_hemorrhage | 1.18185083 |
64 | * MP0002080_prenatal_lethality | 1.17415044 |
65 | MP0000427_abnormal_hair_cycle | 1.16155456 |
66 | MP0003646_muscle_fatigue | 1.15712505 |
67 | MP0000428_abnormal_craniofacial_morphol | 1.14056528 |
68 | MP0002166_altered_tumor_susceptibility | 1.13969520 |
69 | MP0010678_abnormal_skin_adnexa | 1.11500448 |
70 | MP0009672_abnormal_birth_weight | 1.11142959 |
71 | MP0008775_abnormal_heart_ventricle | 1.10008848 |
72 | MP0000733_abnormal_muscle_development | 1.07495640 |
73 | MP0001986_abnormal_taste_sensitivity | 1.06957355 |
74 | MP0005621_abnormal_cell_physiology | 1.04317396 |
75 | MP0001915_intracranial_hemorrhage | 1.04131373 |
76 | MP0009250_abnormal_appendicular_skeleto | 1.03138797 |
77 | MP0005023_abnormal_wound_healing | 1.02259003 |
78 | MP0009697_abnormal_copulation | 0.99011411 |
79 | * MP0002269_muscular_atrophy | 0.98409886 |
80 | MP0004215_abnormal_myocardial_fiber | 0.97435254 |
81 | MP0000015_abnormal_ear_pigmentation | 0.96609936 |
82 | MP0004147_increased_porphyrin_level | 0.96324683 |
83 | MP0003172_abnormal_lysosome_physiology | 0.96198980 |
84 | MP0000371_diluted_coat_color | 0.95447643 |
85 | MP0010368_abnormal_lymphatic_system | 0.95318100 |
86 | MP0008058_abnormal_DNA_repair | 0.92732260 |
87 | MP0002234_abnormal_pharynx_morphology | 0.92164498 |
88 | MP0001145_abnormal_male_reproductive | 0.91902623 |
89 | MP0004036_abnormal_muscle_relaxation | 0.91804214 |
90 | MP0003937_abnormal_limbs/digits/tail_de | 0.91015120 |
91 | MP0002210_abnormal_sex_determination | 0.90939925 |
92 | MP0003115_abnormal_respiratory_system | 0.90520404 |
93 | MP0005384_cellular_phenotype | 0.90004944 |
94 | MP0000003_abnormal_adipose_tissue | 0.89512835 |
95 | MP0003122_maternal_imprinting | 0.86446534 |
96 | MP0002925_abnormal_cardiovascular_devel | 0.86395556 |
97 | MP0003880_abnormal_central_pattern | 0.85036073 |
98 | MP0005266_abnormal_metabolism | 0.84757348 |
99 | MP0000920_abnormal_myelination | 0.83216480 |
100 | MP0001177_atelectasis | 0.81803071 |
101 | MP0003633_abnormal_nervous_system | 0.81012863 |
102 | MP0005310_abnormal_salivary_gland | 0.80775939 |
103 | MP0005187_abnormal_penis_morphology | 0.80749489 |
104 | MP0000762_abnormal_tongue_morphology | 0.79976229 |
105 | MP0008770_decreased_survivor_rate | 0.78948237 |
106 | MP0003252_abnormal_bile_duct | 0.78687387 |
107 | MP0000313_abnormal_cell_death | 0.78349418 |
108 | MP0001348_abnormal_lacrimal_gland | 0.77983124 |
109 | MP0002127_abnormal_cardiovascular_syste | 0.77678066 |
110 | MP0002114_abnormal_axial_skeleton | 0.77284002 |
111 | MP0004742_abnormal_vestibular_system | 0.77225498 |
112 | MP0002896_abnormal_bone_mineralization | 0.77039072 |
113 | MP0008932_abnormal_embryonic_tissue | 0.76844390 |
114 | MP0003567_abnormal_fetal_cardiomyocyte | 0.76645598 |
115 | MP0002161_abnormal_fertility/fecundity | 0.76087031 |
116 | MP0005647_abnormal_sex_gland | 0.75346806 |
117 | MP0001340_abnormal_eyelid_morphology | 0.74703286 |
118 | MP0003935_abnormal_craniofacial_develop | 0.73505292 |
119 | MP0003806_abnormal_nucleotide_metabolis | 0.73246969 |
120 | MP0002282_abnormal_trachea_morphology | 0.73081308 |
121 | MP0000653_abnormal_sex_gland | 0.72397863 |
122 | MP0005408_hypopigmentation | 0.70688887 |
123 | MP0003690_abnormal_glial_cell | 0.69913124 |
124 | MP0000604_amyloidosis | 0.69490373 |
125 | MP0003941_abnormal_skin_development | 0.69179952 |
126 | MP0005171_absent_coat_pigmentation | 0.68959959 |
127 | MP0005395_other_phenotype | 0.68731856 |
128 | MP0001293_anophthalmia | 0.68532189 |
129 | MP0000703_abnormal_thymus_morphology | 0.68327360 |
130 | MP0000383_abnormal_hair_follicle | 0.68265400 |
131 | MP0000516_abnormal_urinary_system | 0.67468519 |
132 | MP0005367_renal/urinary_system_phenotyp | 0.67468519 |
133 | MP0000432_abnormal_head_morphology | 0.67250737 |
134 | MP0002006_tumorigenesis | 0.66466088 |
135 | MP0003868_abnormal_feces_composition | 0.66297184 |
136 | MP0002109_abnormal_limb_morphology | 0.64813880 |
137 | MP0002009_preneoplasia | 0.64371666 |
138 | MP0005666_abnormal_adipose_tissue | 0.64252862 |
139 | MP0001784_abnormal_fluid_regulation | 0.63993267 |
140 | MP0002108_abnormal_muscle_morphology | 0.63717767 |
141 | MP0005377_hearing/vestibular/ear_phenot | 0.63669487 |
142 | MP0003878_abnormal_ear_physiology | 0.63669487 |
143 | MP0003861_abnormal_nervous_system | 0.62915863 |
144 | MP0004859_abnormal_synaptic_plasticity | 0.62615648 |
145 | MP0000747_muscle_weakness | 0.61956183 |
146 | MP0002092_abnormal_eye_morphology | 0.61751689 |
147 | MP0000266_abnormal_heart_morphology | 0.61150206 |
148 | MP0005275_abnormal_skin_tensile | 0.60708121 |
149 | MP0003329_amyloid_beta_deposits | 0.59189947 |
150 | * MP0004811_abnormal_neuron_physiology | 0.58217660 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute myeloid leukemia (HP:0004808) | 4.57429310 |
2 | Chronic hepatic failure (HP:0100626) | 3.99099217 |
3 | Curly hair (HP:0002212) | 3.69003498 |
4 | Volvulus (HP:0002580) | 3.67100090 |
5 | Carpal bone hypoplasia (HP:0001498) | 3.46475713 |
6 | Macroorchidism (HP:0000053) | 3.28199000 |
7 | Heterotopia (HP:0002282) | 3.22176004 |
8 | Short 4th metacarpal (HP:0010044) | 3.17259869 |
9 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.17259869 |
10 | Absent frontal sinuses (HP:0002688) | 3.08599364 |
11 | Thyroiditis (HP:0100646) | 3.08179819 |
12 | Thyroid carcinoma (HP:0002890) | 3.06215035 |
13 | Chromsome breakage (HP:0040012) | 3.04677481 |
14 | Protruding tongue (HP:0010808) | 3.03825960 |
15 | Abnormality of DNA repair (HP:0003254) | 3.01440834 |
16 | Spinal muscular atrophy (HP:0007269) | 2.89440624 |
17 | Metaphyseal dysplasia (HP:0100255) | 2.85510655 |
18 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.78327544 |
19 | Subacute progressive viral hepatitis (HP:0006572) | 2.76833445 |
20 | Cystic hygroma (HP:0000476) | 2.72782470 |
21 | Deep philtrum (HP:0002002) | 2.70042582 |
22 | Entropion (HP:0000621) | 2.65158743 |
23 | Astrocytoma (HP:0009592) | 2.63595634 |
24 | Abnormality of the astrocytes (HP:0100707) | 2.63595634 |
25 | Fair hair (HP:0002286) | 2.56804087 |
26 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.55785721 |
27 | Hip dysplasia (HP:0001385) | 2.52927833 |
28 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.52653254 |
29 | Papilledema (HP:0001085) | 2.48712105 |
30 | Truncal obesity (HP:0001956) | 2.44662665 |
31 | Hyperventilation (HP:0002883) | 2.41144472 |
32 | Abnormality of oral frenula (HP:0000190) | 2.39712870 |
33 | Limb hypertonia (HP:0002509) | 2.39377385 |
34 | Ankyloglossia (HP:0010296) | 2.37025670 |
35 | Abnormality of the lower motor neuron (HP:0002366) | 2.36052642 |
36 | Severe combined immunodeficiency (HP:0004430) | 2.35301402 |
37 | Abnormality of the fingertips (HP:0001211) | 2.34530156 |
38 | Abnormality of the 4th metacarpal (HP:0010012) | 2.34450194 |
39 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.34377599 |
40 | Deviation of the thumb (HP:0009603) | 2.34263156 |
41 | Insidious onset (HP:0003587) | 2.33129046 |
42 | Termporal pattern (HP:0011008) | 2.33129046 |
43 | Small hand (HP:0200055) | 2.30961593 |
44 | Relative macrocephaly (HP:0004482) | 2.30881520 |
45 | Ependymoma (HP:0002888) | 2.28972502 |
46 | Abnormal foot bone ossification (HP:0010675) | 2.26862574 |
47 | Hypopigmentation of the fundus (HP:0007894) | 2.25781586 |
48 | Glioma (HP:0009733) | 2.25680439 |
49 | Sandal gap (HP:0001852) | 2.25621063 |
50 | Obsessive-compulsive behavior (HP:0000722) | 2.24133835 |
51 | High pitched voice (HP:0001620) | 2.23143570 |
52 | Renal cortical cysts (HP:0000803) | 2.22399211 |
53 | Broad alveolar ridges (HP:0000187) | 2.17195957 |
54 | Increased nuchal translucency (HP:0010880) | 2.17156909 |
55 | Proximal placement of thumb (HP:0009623) | 2.16158704 |
56 | Dysmetric saccades (HP:0000641) | 2.15861597 |
57 | Impaired smooth pursuit (HP:0007772) | 2.15222711 |
58 | Cutaneous melanoma (HP:0012056) | 2.14306267 |
59 | Tubulointerstitial nephritis (HP:0001970) | 2.13048469 |
60 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.09506515 |
61 | Long clavicles (HP:0000890) | 2.09482059 |
62 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.09383801 |
63 | Capillary hemangiomas (HP:0005306) | 2.08689209 |
64 | Thickened helices (HP:0000391) | 2.07977972 |
65 | Retinal dysplasia (HP:0007973) | 2.02857688 |
66 | Difficulty running (HP:0009046) | 2.02832227 |
67 | Aortic aneurysm (HP:0004942) | 2.01963947 |
68 | Hypobetalipoproteinemia (HP:0003563) | 2.01628376 |
69 | Resting tremor (HP:0002322) | 2.01282237 |
70 | Poikiloderma (HP:0001029) | 2.01078470 |
71 | Generalized hypopigmentation of hair (HP:0011358) | 2.00266005 |
72 | Submucous cleft hard palate (HP:0000176) | 1.98255549 |
73 | T lymphocytopenia (HP:0005403) | 1.97615892 |
74 | Increased mean platelet volume (HP:0011877) | 1.97408909 |
75 | Hypoplastic ischia (HP:0003175) | 1.96179682 |
76 | Urinary urgency (HP:0000012) | 1.95182623 |
77 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.94978013 |
78 | Broad thumb (HP:0011304) | 1.92706329 |
79 | Bell-shaped thorax (HP:0001591) | 1.91611049 |
80 | Narrow palate (HP:0000189) | 1.90753760 |
81 | Spondylolisthesis (HP:0003302) | 1.89150816 |
82 | Abnormality of the ileum (HP:0001549) | 1.88775846 |
83 | Low anterior hairline (HP:0000294) | 1.88633842 |
84 | Abnormality of the calcaneus (HP:0008364) | 1.87678877 |
85 | Drooling (HP:0002307) | 1.87142745 |
86 | Embryonal renal neoplasm (HP:0011794) | 1.87012403 |
87 | Barrel-shaped chest (HP:0001552) | 1.86734705 |
88 | Prominent nose (HP:0000448) | 1.86330553 |
89 | Intestinal atresia (HP:0011100) | 1.85655540 |
90 | Combined immunodeficiency (HP:0005387) | 1.85631637 |
91 | Proximal amyotrophy (HP:0007126) | 1.83030706 |
92 | Rhabdomyosarcoma (HP:0002859) | 1.82716530 |
93 | Hyperkalemia (HP:0002153) | 1.81520092 |
94 | Papillary thyroid carcinoma (HP:0002895) | 1.81282849 |
95 | Intellectual disability, moderate (HP:0002342) | 1.80356821 |
96 | Abnormality of the corticospinal tract (HP:0002492) | 1.79933511 |
97 | Cortical dysplasia (HP:0002539) | 1.78987252 |
98 | Long eyelashes (HP:0000527) | 1.78302559 |
99 | Limited elbow extension (HP:0001377) | 1.77985002 |
100 | Global brain atrophy (HP:0002283) | 1.77788566 |
101 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.77387142 |
102 | Fibular aplasia (HP:0002990) | 1.76798616 |
103 | Abnormality of the ischium (HP:0003174) | 1.74662150 |
104 | Cerebral aneurysm (HP:0004944) | 1.74419155 |
105 | Pelvic girdle muscle weakness (HP:0003749) | 1.73916370 |
106 | Complete atrioventricular canal defect (HP:0001674) | 1.72229177 |
107 | Myelodysplasia (HP:0002863) | 1.72105079 |
108 | Aqueductal stenosis (HP:0002410) | 1.71483113 |
109 | Abnormality of the renal cortex (HP:0011035) | 1.69616668 |
110 | Neoplasm of the oral cavity (HP:0100649) | 1.69523049 |
111 | Abnormality of T cell number (HP:0011839) | 1.69148141 |
112 | Ectopic kidney (HP:0000086) | 1.68752840 |
113 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.68496013 |
114 | Abnormality of methionine metabolism (HP:0010901) | 1.68407049 |
115 | Mitral valve prolapse (HP:0001634) | 1.67997646 |
116 | Cutis marmorata (HP:0000965) | 1.67627331 |
117 | Medulloblastoma (HP:0002885) | 1.67540279 |
118 | Hypoplastic labia majora (HP:0000059) | 1.66574507 |
119 | Midline defect of the nose (HP:0004122) | 1.66175456 |
120 | Flat acetabular roof (HP:0003180) | 1.65564912 |
121 | Abnormal platelet volume (HP:0011876) | 1.64771773 |
122 | Cerebellar dysplasia (HP:0007033) | 1.63965706 |
123 | Broad-based gait (HP:0002136) | 1.63805068 |
124 | Metaphyseal cupping (HP:0003021) | 1.63613475 |
125 | Cafe-au-lait spot (HP:0000957) | 1.63305864 |
126 | Abnormality of the frontal sinuses (HP:0002687) | 1.61580164 |
127 | Freckling (HP:0001480) | 1.61304386 |
128 | Excessive salivation (HP:0003781) | 1.61050327 |
129 | Bifid tongue (HP:0010297) | 1.60640082 |
130 | Abnormality of the costochondral junction (HP:0000919) | 1.60599481 |
131 | Scanning speech (HP:0002168) | 1.60356271 |
132 | Bowel diverticulosis (HP:0005222) | 1.59750405 |
133 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.59731075 |
134 | Exotropia (HP:0000577) | 1.59429803 |
135 | Meckel diverticulum (HP:0002245) | 1.58704555 |
136 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.57956482 |
137 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.57956482 |
138 | Skull defect (HP:0001362) | 1.57009623 |
139 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.56953207 |
140 | Renovascular hypertension (HP:0100817) | 1.56782931 |
141 | Biliary tract neoplasm (HP:0100574) | 1.56636204 |
142 | Spastic gait (HP:0002064) | 1.56268047 |
143 | Abnormality of chromosome stability (HP:0003220) | 1.56217989 |
144 | Fibrous tissue neoplasm (HP:0012316) | 1.55695818 |
145 | Abnormality of macular pigmentation (HP:0008002) | 1.55687509 |
146 | Gastrointestinal carcinoma (HP:0002672) | 1.55608007 |
147 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.55608007 |
148 | Pheochromocytoma (HP:0002666) | 1.55607032 |
149 | Abnormality of chromosome segregation (HP:0002916) | 1.55605615 |
150 | Open mouth (HP:0000194) | 1.54856901 |
151 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.54776916 |
152 | Short ribs (HP:0000773) | 1.53960844 |
153 | Broad palm (HP:0001169) | 1.53567396 |
154 | Distal upper limb amyotrophy (HP:0007149) | 1.53395095 |
155 | Upper limb amyotrophy (HP:0009129) | 1.53395095 |
156 | Acanthocytosis (HP:0001927) | 1.53267512 |
157 | Aneurysm (HP:0002617) | 1.53154224 |
158 | Amyotrophic lateral sclerosis (HP:0007354) | 1.52946051 |
159 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.52805647 |
160 | Limited hip movement (HP:0008800) | 1.52717678 |
161 | Absent eyebrow (HP:0002223) | 1.52397749 |
162 | Abnormal biliary tract morphology (HP:0012440) | 1.52197835 |
163 | Large earlobe (HP:0009748) | 1.52123552 |
164 | Rhizomelia (HP:0008905) | 1.52082871 |
165 | Cervical subluxation (HP:0003308) | 1.52073662 |
166 | Fetal akinesia sequence (HP:0001989) | 1.51908586 |
167 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.51509238 |
168 | Impulsivity (HP:0100710) | 1.51508917 |
169 | Hand muscle atrophy (HP:0009130) | 1.51115995 |
170 | Small epiphyses (HP:0010585) | 1.50764610 |
171 | Upper limb muscle weakness (HP:0003484) | 1.50689463 |
172 | Basal cell carcinoma (HP:0002671) | 1.49766729 |
173 | Lip pit (HP:0100267) | 1.49257232 |
174 | Ectropion (HP:0000656) | 1.47025856 |
175 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.46857870 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 3.11012677 |
2 | CDC7 | 2.98672507 |
3 | NUAK1 | 2.78370933 |
4 | SCYL2 | 2.67492344 |
5 | PRKD3 | 2.62944520 |
6 | PDK4 | 2.59460275 |
7 | PDK3 | 2.59460275 |
8 | PLK4 | 2.54539299 |
9 | PKN2 | 2.33348554 |
10 | TAOK3 | 2.19611594 |
11 | EIF2AK3 | 2.12625867 |
12 | MELK | 2.10721272 |
13 | NEK2 | 1.98006170 |
14 | BRD4 | 1.97496151 |
15 | LATS1 | 1.95766474 |
16 | EEF2K | 1.91632411 |
17 | SRPK1 | 1.74920126 |
18 | MST4 | 1.74034244 |
19 | NEK1 | 1.72008601 |
20 | TTK | 1.69907219 |
21 | DYRK2 | 1.65377395 |
22 | FRK | 1.58972139 |
23 | ERBB3 | 1.55574805 |
24 | PDK2 | 1.55527702 |
25 | PDGFRA | 1.55282161 |
26 | PASK | 1.51733646 |
27 | HIPK2 | 1.48762738 |
28 | MET | 1.48211899 |
29 | TTN | 1.47944931 |
30 | INSRR | 1.46166856 |
31 | STK38L | 1.42667529 |
32 | SIK1 | 1.41327251 |
33 | AKT3 | 1.39482491 |
34 | ATR | 1.39466138 |
35 | BRSK2 | 1.39008722 |
36 | FGFR2 | 1.38463067 |
37 | TNIK | 1.37580380 |
38 | TRIM28 | 1.35092555 |
39 | BCR | 1.33315638 |
40 | ACVR1B | 1.25752061 |
41 | MKNK1 | 1.23908794 |
42 | PNCK | 1.23262557 |
43 | CAMK1D | 1.22911595 |
44 | STK10 | 1.22880952 |
45 | MKNK2 | 1.21874054 |
46 | ALK | 1.21338966 |
47 | MAP3K12 | 1.19209942 |
48 | PTK6 | 1.17673415 |
49 | FLT3 | 1.17241712 |
50 | ZAK | 1.16648358 |
51 | PLK3 | 1.16094719 |
52 | PDGFRB | 1.15782641 |
53 | CHEK1 | 1.15030029 |
54 | PBK | 1.11696475 |
55 | TSSK6 | 1.10085780 |
56 | STK3 | 1.09772798 |
57 | CAMK1G | 1.09566933 |
58 | WNK3 | 1.07540750 |
59 | MAP4K2 | 1.06868978 |
60 | FGFR1 | 1.06296770 |
61 | MTOR | 1.04111685 |
62 | ATM | 1.03872293 |
63 | DDR2 | 0.99078305 |
64 | MAP3K8 | 0.98635094 |
65 | STK38 | 0.97868116 |
66 | RAF1 | 0.97780974 |
67 | JAK3 | 0.95719453 |
68 | TRIB3 | 0.95181677 |
69 | FGFR3 | 0.93520169 |
70 | TESK1 | 0.93347060 |
71 | SGK494 | 0.91657362 |
72 | SGK223 | 0.91657362 |
73 | WEE1 | 0.91633095 |
74 | RPS6KB1 | 0.90435202 |
75 | MAP3K4 | 0.90037306 |
76 | PAK3 | 0.88998337 |
77 | YES1 | 0.88360187 |
78 | FER | 0.88112278 |
79 | CASK | 0.87715564 |
80 | PAK2 | 0.86678193 |
81 | TEC | 0.86249909 |
82 | OBSCN | 0.86127137 |
83 | STK39 | 0.85274276 |
84 | CDK6 | 0.84512382 |
85 | RET | 0.82593679 |
86 | PDK1 | 0.82544199 |
87 | CSNK1D | 0.81120653 |
88 | TIE1 | 0.80846662 |
89 | EPHA3 | 0.79806259 |
90 | PRKCH | 0.79499966 |
91 | MAP3K10 | 0.78643509 |
92 | CDK4 | 0.76949347 |
93 | TYRO3 | 0.76115449 |
94 | MAP3K9 | 0.73698312 |
95 | JAK1 | 0.71607386 |
96 | BMPR1B | 0.70845985 |
97 | CHEK2 | 0.70658676 |
98 | CSNK1A1L | 0.70336421 |
99 | CDK2 | 0.70060562 |
100 | MARK1 | 0.69588228 |
101 | CDK1 | 0.69582237 |
102 | PIK3CG | 0.69284987 |
103 | NLK | 0.68650696 |
104 | PRKAA2 | 0.66232972 |
105 | MAP3K2 | 0.65738041 |
106 | BRAF | 0.65598186 |
107 | SGK3 | 0.65392094 |
108 | PRKDC | 0.64658526 |
109 | KSR2 | 0.63844755 |
110 | BRSK1 | 0.63499891 |
111 | PAK6 | 0.61570615 |
112 | KSR1 | 0.59681523 |
113 | WNK1 | 0.59099509 |
114 | BMX | 0.58314185 |
115 | MAP3K7 | 0.58151415 |
116 | EIF2AK2 | 0.57819164 |
117 | PLK1 | 0.55853104 |
118 | RIPK1 | 0.53529574 |
119 | PDPK1 | 0.53137822 |
120 | ICK | 0.52621348 |
121 | CHUK | 0.52245921 |
122 | RPS6KB2 | 0.50440538 |
123 | MAP3K13 | 0.49849630 |
124 | TGFBR1 | 0.49650121 |
125 | PTK2B | 0.48695174 |
126 | PLK2 | 0.48070631 |
127 | NEK6 | 0.47814024 |
128 | CSNK1G2 | 0.47475257 |
129 | AURKB | 0.47453241 |
130 | CDK9 | 0.46579633 |
131 | CSNK1E | 0.46439097 |
132 | MAPK14 | 0.44383225 |
133 | TRPM7 | 0.43688872 |
134 | CDC42BPA | 0.42898874 |
135 | SGK1 | 0.42786702 |
136 | MAPK10 | 0.42240901 |
137 | CLK1 | 0.41649861 |
138 | MUSK | 0.41028775 |
139 | GSK3B | 0.40804271 |
140 | NTRK3 | 0.40705187 |
141 | INSR | 0.40213948 |
142 | STK4 | 0.39066153 |
143 | PTK2 | 0.38050388 |
144 | SGK2 | 0.37791023 |
145 | TGFBR2 | 0.37748822 |
146 | NME1 | 0.36851898 |
147 | TAF1 | 0.36029399 |
148 | PRKCE | 0.34643142 |
149 | ITK | 0.34301216 |
150 | RPS6KA4 | 0.34185251 |
151 | PRKAA1 | 0.33914721 |
152 | CSNK1G1 | 0.33118978 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.16510574 |
2 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.00901184 |
3 | Lysine degradation_Homo sapiens_hsa00310 | 1.90144645 |
4 | Circadian rhythm_Homo sapiens_hsa04710 | 1.89746516 |
5 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.86097354 |
6 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.80576750 |
7 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.79253377 |
8 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.77339544 |
9 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.74634463 |
10 | Cell cycle_Homo sapiens_hsa04110 | 1.71234334 |
11 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.70867518 |
12 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.64291949 |
13 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.61344261 |
14 | RNA transport_Homo sapiens_hsa03013 | 1.61057415 |
15 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.57774429 |
16 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.57679987 |
17 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.55262725 |
18 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.50522621 |
19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.49476648 |
20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.48188674 |
21 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.40260650 |
22 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.37508945 |
23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.33318612 |
24 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.31949929 |
25 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.31197815 |
26 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.29624829 |
27 | Glioma_Homo sapiens_hsa05214 | 1.23209173 |
28 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.22665467 |
29 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.22563628 |
30 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.22269394 |
31 | Long-term potentiation_Homo sapiens_hsa04720 | 1.20789187 |
32 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.19324898 |
33 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.17307105 |
34 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.14906479 |
35 | Mismatch repair_Homo sapiens_hsa03430 | 1.13968884 |
36 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.12788569 |
37 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.08766800 |
38 | DNA replication_Homo sapiens_hsa03030 | 1.04475642 |
39 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.04384017 |
40 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.03661891 |
41 | Alcoholism_Homo sapiens_hsa05034 | 1.03562290 |
42 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.02275842 |
43 | Legionellosis_Homo sapiens_hsa05134 | 1.01735844 |
44 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.00987943 |
45 | Focal adhesion_Homo sapiens_hsa04510 | 1.00533205 |
46 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.00493450 |
47 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.99070903 |
48 | Adherens junction_Homo sapiens_hsa04520 | 0.98975803 |
49 | Colorectal cancer_Homo sapiens_hsa05210 | 0.98330882 |
50 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.98304288 |
51 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.98279084 |
52 | Endometrial cancer_Homo sapiens_hsa05213 | 0.97670132 |
53 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.94035614 |
54 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.93662448 |
55 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.92866420 |
56 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.90765340 |
57 | Prostate cancer_Homo sapiens_hsa05215 | 0.90702939 |
58 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.90485496 |
59 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.87813606 |
60 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.86049174 |
61 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.85781254 |
62 | Insulin resistance_Homo sapiens_hsa04931 | 0.85687839 |
63 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.84424086 |
64 | RNA degradation_Homo sapiens_hsa03018 | 0.80093711 |
65 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.80050398 |
66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.79735190 |
67 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.79493554 |
68 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.78224436 |
69 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.78221081 |
70 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.78162951 |
71 | Protein export_Homo sapiens_hsa03060 | 0.78079844 |
72 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.77984576 |
73 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.76505381 |
74 | Long-term depression_Homo sapiens_hsa04730 | 0.76361566 |
75 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.76149618 |
76 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.72587666 |
77 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.71213406 |
78 | Taste transduction_Homo sapiens_hsa04742 | 0.70228173 |
79 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.68992864 |
80 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.68659232 |
81 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.67726633 |
82 | ABC transporters_Homo sapiens_hsa02010 | 0.66100981 |
83 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.65971914 |
84 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.65926309 |
85 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.63597767 |
86 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.63437363 |
87 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.63395229 |
88 | Platelet activation_Homo sapiens_hsa04611 | 0.63125820 |
89 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.62797056 |
90 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.62209749 |
91 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.62109723 |
92 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.61052052 |
93 | HTLV-I infection_Homo sapiens_hsa05166 | 0.60869418 |
94 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.60332324 |
95 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.60312726 |
96 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.58932002 |
97 | Spliceosome_Homo sapiens_hsa03040 | 0.58279888 |
98 | Hepatitis B_Homo sapiens_hsa05161 | 0.58067269 |
99 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.58008177 |
100 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.57711697 |
101 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.55784769 |
102 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.55559992 |
103 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.54300457 |
104 | Renin secretion_Homo sapiens_hsa04924 | 0.54182995 |
105 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.53991934 |
106 | Insulin secretion_Homo sapiens_hsa04911 | 0.53826577 |
107 | Thyroid cancer_Homo sapiens_hsa05216 | 0.53721916 |
108 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.52104055 |
109 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.52072754 |
110 | Nicotine addiction_Homo sapiens_hsa05033 | 0.51136233 |
111 | Homologous recombination_Homo sapiens_hsa03440 | 0.50913540 |
112 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.50886460 |
113 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.50160891 |
114 | Tight junction_Homo sapiens_hsa04530 | 0.49310536 |
115 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.48963647 |
116 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.48557923 |
117 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.48420668 |
118 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.47613783 |
119 | Melanoma_Homo sapiens_hsa05218 | 0.47570082 |
120 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.47016129 |
121 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.46622905 |
122 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.45912211 |
123 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.44868105 |
124 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.44695611 |
125 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.44511302 |
126 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.44068139 |
127 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.43963627 |
128 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.43538745 |
129 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.43160512 |
130 | Bile secretion_Homo sapiens_hsa04976 | 0.43016553 |
131 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.42996626 |
132 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.42868381 |
133 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.42811775 |
134 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.42700905 |
135 | Purine metabolism_Homo sapiens_hsa00230 | 0.41706863 |
136 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.41567260 |
137 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41074692 |
138 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.40762457 |
139 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.40362473 |
140 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.40297772 |
141 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.39163731 |
142 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.38708103 |
143 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.38412196 |
144 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.36125054 |