LTV1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1purine nucleobase biosynthetic process (GO:0009113)4.87056376
2nucleobase biosynthetic process (GO:0046112)4.81918739
3formation of translation preinitiation complex (GO:0001731)4.72287998
4ribosome assembly (GO:0042255)4.54136807
5mitotic metaphase plate congression (GO:0007080)4.47510841
6DNA strand elongation involved in DNA replication (GO:0006271)4.29928008
7maturation of SSU-rRNA (GO:0030490)4.28313798
8ribosome biogenesis (GO:0042254)4.26658019
9DNA replication checkpoint (GO:0000076)4.19436628
10DNA replication initiation (GO:0006270)4.19164723
11mitotic nuclear envelope disassembly (GO:0007077)4.09811941
12DNA strand elongation (GO:0022616)4.07542217
13nuclear pore organization (GO:0006999)4.07112886
14establishment of integrated proviral latency (GO:0075713)4.00004753
15DNA deamination (GO:0045006)3.98264257
16telomere maintenance via semi-conservative replication (GO:0032201)3.91429833
17protein localization to kinetochore (GO:0034501)3.89789601
18metaphase plate congression (GO:0051310)3.84151266
19ribonucleoprotein complex biogenesis (GO:0022613)3.83504233
20nuclear pore complex assembly (GO:0051292)3.81437911
21IMP biosynthetic process (GO:0006188)3.79000489
22nuclear envelope disassembly (GO:0051081)3.78235046
23membrane disassembly (GO:0030397)3.78235046
24establishment of protein localization to mitochondrial membrane (GO:0090151)3.77836455
25rRNA methylation (GO:0031167)3.74959526
26cullin deneddylation (GO:0010388)3.71719996
27regulation of spindle organization (GO:0090224)3.70009883
28ribosomal large subunit biogenesis (GO:0042273)3.68024131
29CENP-A containing nucleosome assembly (GO:0034080)3.65607952
30telomere maintenance via recombination (GO:0000722)3.62118859
31regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.61447224
32DNA unwinding involved in DNA replication (GO:0006268)3.57802154
33chromatin remodeling at centromere (GO:0031055)3.57688813
34rRNA processing (GO:0006364)3.55931094
35regulation of mitotic spindle checkpoint (GO:1903504)3.55857153
36regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.55857153
37proteasome assembly (GO:0043248)3.55546890
38ribosomal small subunit assembly (GO:0000028)3.55382894
39transcription from mitochondrial promoter (GO:0006390)3.52244716
40chaperone-mediated protein transport (GO:0072321)3.51760043
41folic acid-containing compound biosynthetic process (GO:0009396)3.45221506
42protein deneddylation (GO:0000338)3.44624893
43rRNA metabolic process (GO:0016072)3.44238667
44mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.43261535
45mitotic recombination (GO:0006312)3.42684916
46IMP metabolic process (GO:0046040)3.39765746
47folic acid metabolic process (GO:0046655)3.39263770
48anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.38187087
49exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.35731434
50spliceosomal snRNP assembly (GO:0000387)3.35621027
51rRNA modification (GO:0000154)3.34924208
52regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.33854526
53DNA replication-dependent nucleosome assembly (GO:0006335)3.33535381
54DNA replication-dependent nucleosome organization (GO:0034723)3.33535381
55negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.32848103
56establishment of chromosome localization (GO:0051303)3.32832077
57DNA replication-independent nucleosome organization (GO:0034724)3.32784477
58DNA replication-independent nucleosome assembly (GO:0006336)3.32784477
59regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.32690672
60protein localization to chromosome, centromeric region (GO:0071459)3.32470840
61regulation of centriole replication (GO:0046599)3.31801774
62transcription elongation from RNA polymerase III promoter (GO:0006385)3.31424905
63termination of RNA polymerase III transcription (GO:0006386)3.31424905
64positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.31385635
65regulation of cellular amino acid metabolic process (GO:0006521)3.31244302
66DNA catabolic process, exonucleolytic (GO:0000738)3.27847726
67telomere maintenance via telomere lengthening (GO:0010833)3.26479416
68DNA double-strand break processing (GO:0000729)3.26082913
69signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.25837565
70signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.25837565
71signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.25837565
72pseudouridine synthesis (GO:0001522)3.25594295
73nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.25228668
74DNA damage response, detection of DNA damage (GO:0042769)3.24441315
75DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.24321716
76mitochondrial RNA metabolic process (GO:0000959)3.24304632
77intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.23344886
78signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.23344886
79histone mRNA metabolic process (GO:0008334)3.22356916
80kinetochore organization (GO:0051383)3.20730531
81signal transduction involved in DNA damage checkpoint (GO:0072422)3.20472835
82signal transduction involved in DNA integrity checkpoint (GO:0072401)3.20472835
83translational initiation (GO:0006413)3.19302606
84regulation of ubiquitin-protein transferase activity (GO:0051438)3.18107392
85positive regulation of chromosome segregation (GO:0051984)3.17273424
86sister chromatid segregation (GO:0000819)3.16422280
87regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.16369918
88attachment of spindle microtubules to kinetochore (GO:0008608)3.15938269
89pore complex assembly (GO:0046931)3.15093382
90non-recombinational repair (GO:0000726)3.14986083
91double-strand break repair via nonhomologous end joining (GO:0006303)3.14986083
92signal transduction involved in cell cycle checkpoint (GO:0072395)3.13535296
93DNA ligation (GO:0006266)3.13455728
94histone exchange (GO:0043486)3.13334867
95transcription-coupled nucleotide-excision repair (GO:0006283)3.11324485
96protein targeting to mitochondrion (GO:0006626)3.11149195
97regulation of mitochondrial translation (GO:0070129)3.10545358
98regulation of helicase activity (GO:0051095)3.09885153
997-methylguanosine mRNA capping (GO:0006370)3.09514948
100regulation of mitotic spindle organization (GO:0060236)3.08887669
101regulation of ligase activity (GO:0051340)3.08705275
102ribosomal small subunit biogenesis (GO:0042274)3.08562516
103G1/S transition of mitotic cell cycle (GO:0000082)3.08366659
104cell cycle G1/S phase transition (GO:0044843)3.08366659
105translational termination (GO:0006415)3.06769267
1067-methylguanosine RNA capping (GO:0009452)3.03882626
107RNA capping (GO:0036260)3.03882626
108negative regulation of ligase activity (GO:0051352)3.03624602
109negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.03624602
110viral transcription (GO:0019083)3.01806646
111termination of RNA polymerase I transcription (GO:0006363)3.00576190
112transcription from RNA polymerase I promoter (GO:0006360)3.00471985
113spindle checkpoint (GO:0031577)3.00102232
114nuclear envelope organization (GO:0006998)2.99715003
115kinetochore assembly (GO:0051382)2.98849932
116nucleotide-excision repair, DNA gap filling (GO:0006297)2.98098801
117regulation of double-strand break repair via homologous recombination (GO:0010569)2.97292125
118positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.96712973
119transcription elongation from RNA polymerase I promoter (GO:0006362)2.96597409
120negative regulation of chromosome segregation (GO:0051985)2.96143162
121maturation of 5.8S rRNA (GO:0000460)2.96054583
122negative regulation of mitotic sister chromatid segregation (GO:0033048)2.93889517
123negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.93889517
124negative regulation of sister chromatid segregation (GO:0033046)2.93889517
125negative regulation of mitotic sister chromatid separation (GO:2000816)2.93889517
126mitotic spindle checkpoint (GO:0071174)2.91044880
127mitotic spindle assembly checkpoint (GO:0007094)2.90832710
128translational elongation (GO:0006414)2.90752856
129regulation of chromosome segregation (GO:0051983)2.89840956
130regulation of translation in response to stress (GO:0043555)2.89547024
131mitotic sister chromatid segregation (GO:0000070)2.89303269
132spindle assembly checkpoint (GO:0071173)2.89161339
133regulation of mitotic metaphase/anaphase transition (GO:0030071)2.86093601
134negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.85320139
135cellular component biogenesis (GO:0044085)2.84270245
136positive regulation of ligase activity (GO:0051351)2.82403586
137regulation of centrosome cycle (GO:0046605)2.82189520
138regulation of nuclear cell cycle DNA replication (GO:0033262)2.81289803

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.58470185
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.37922070
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.67899830
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.45753192
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.41115226
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.33022440
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.09174116
8* GABP_17652178_ChIP-ChIP_JURKAT_Human3.08408759
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.01165367
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.00129677
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.97910115
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.92881747
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.88070600
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.86733730
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.85866762
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.42089156
17VDR_23849224_ChIP-Seq_CD4+_Human2.35556075
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.29636438
19AR_21909140_ChIP-Seq_LNCAP_Human2.29537736
20* XRN2_22483619_ChIP-Seq_HELA_Human2.28859810
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.21910667
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.20127453
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.13249398
24MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.12165433
25E2F1_18555785_ChIP-Seq_MESCs_Mouse2.06504097
26DCP1A_22483619_ChIP-Seq_HELA_Human2.04773405
27EGR1_19374776_ChIP-ChIP_THP-1_Human1.99095475
28FOXP3_21729870_ChIP-Seq_TREG_Human1.98170251
29ELF1_17652178_ChIP-ChIP_JURKAT_Human1.95732051
30MYCN_18555785_ChIP-Seq_MESCs_Mouse1.94791633
31* GABP_19822575_ChIP-Seq_HepG2_Human1.94775637
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.86873989
33E2F1_21310950_ChIP-Seq_MCF-7_Human1.80997196
34SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.80443882
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.79569855
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.78030571
37* TTF2_22483619_ChIP-Seq_HELA_Human1.77161650
38* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.75934353
39* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.72121284
40THAP11_20581084_ChIP-Seq_MESCs_Mouse1.70271877
41ELK1_19687146_ChIP-ChIP_HELA_Human1.69649844
42NANOG_18555785_ChIP-Seq_MESCs_Mouse1.68222408
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.65078420
44CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.58924393
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.57637135
46SRF_21415370_ChIP-Seq_HL-1_Mouse1.54469511
47YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.53611838
48YY1_21170310_ChIP-Seq_MESCs_Mouse1.52481995
49SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.49062032
50TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.49061373
51KDM5A_27292631_Chip-Seq_BREAST_Human1.46811821
52HOXB4_20404135_ChIP-ChIP_EML_Mouse1.46004918
53MYC_22102868_ChIP-Seq_BL_Human1.43544865
54CIITA_25753668_ChIP-Seq_RAJI_Human1.43280432
55NOTCH1_21737748_ChIP-Seq_TLL_Human1.35105817
56STAT3_1855785_ChIP-Seq_MESCs_Mouse1.31179441
57SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.30242765
58ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.28514460
59KLF4_18555785_ChIP-Seq_MESCs_Mouse1.28394591
60MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.26535327
61ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24678985
62ERG_20887958_ChIP-Seq_HPC-7_Mouse1.24415705
63FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.23459296
64CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.21592576
65TFEB_21752829_ChIP-Seq_HELA_Human1.21193878
66POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.19756242
67PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19721690
68PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.18729290
69EWS_26573619_Chip-Seq_HEK293_Human1.15823637
70E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.13552348
71PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.12912206
72CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12829245
73RBPJ_22232070_ChIP-Seq_NCS_Mouse1.12520130
74HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.11009830
75POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.08304976
76SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.06852891
77DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04237251
78* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.03275229
79TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.02526838
80SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.02281103
81ELK1_22589737_ChIP-Seq_MCF10A_Human1.02063510
82SPI1_23547873_ChIP-Seq_NB4_Human1.01558394
83CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.01413460
84BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.00552725
85FUS_26573619_Chip-Seq_HEK293_Human0.99592682
86* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99418878
87CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.97684999
88FLI1_27457419_Chip-Seq_LIVER_Mouse0.96153681
89TP63_19390658_ChIP-ChIP_HaCaT_Human0.96062727
90HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94923271
91NANOG_16153702_ChIP-ChIP_HESCs_Human0.92383768
92KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.92238801
93CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90988724
94KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.90621990
95MYC_18940864_ChIP-ChIP_HL60_Human0.88197508
96GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86935938
97CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86916091
98CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.86123553
99DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.85288781
100SOX2_18555785_ChIP-Seq_MESCs_Mouse0.83263357
101SOX17_20123909_ChIP-Seq_XEN_Mouse0.82827097
102HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.80267187
103VDR_22108803_ChIP-Seq_LS180_Human0.77114556
104ZNF274_21170338_ChIP-Seq_K562_Hela0.76666539
105TCF3_18692474_ChIP-Seq_MEFs_Mouse0.76544991
106ELF5_23300383_ChIP-Seq_T47D_Human0.75605812
107NANOG_21062744_ChIP-ChIP_HESCs_Human0.72818637
108VDR_21846776_ChIP-Seq_THP-1_Human0.72800660
109CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.72091965
110OCT4_18692474_ChIP-Seq_MEFs_Mouse0.72044115
111MYB_21317192_ChIP-Seq_ERMYB_Mouse0.71789708
112* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71596538
113SOX2_18692474_ChIP-Seq_MEFs_Mouse0.71570100
114SALL1_21062744_ChIP-ChIP_HESCs_Human0.71011864
115POU5F1_16153702_ChIP-ChIP_HESCs_Human0.70917963
116SOX2_16153702_ChIP-ChIP_HESCs_Human0.69089325
117PCGF2_27294783_Chip-Seq_ESCs_Mouse0.64721412
118SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.63303990

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.77946291
2MP0004957_abnormal_blastocyst_morpholog4.43782109
3MP0010094_abnormal_chromosome_stability4.26960070
4MP0003111_abnormal_nucleus_morphology4.22907164
5MP0008057_abnormal_DNA_replication4.08342135
6MP0003077_abnormal_cell_cycle3.85740228
7MP0008058_abnormal_DNA_repair3.40779355
8MP0008007_abnormal_cellular_replicative2.81351333
9MP0008932_abnormal_embryonic_tissue2.55952049
10MP0003123_paternal_imprinting2.42151737
11MP0001730_embryonic_growth_arrest2.40701117
12MP0002396_abnormal_hematopoietic_system2.31428832
13MP0000350_abnormal_cell_proliferation2.16955725
14MP0003806_abnormal_nucleotide_metabolis2.12849262
15MP0010352_gastrointestinal_tract_polyps2.05278537
16MP0006292_abnormal_olfactory_placode2.03642767
17MP0003786_premature_aging2.01763882
18MP0003718_maternal_effect1.96601554
19MP0009333_abnormal_splenocyte_physiolog1.84719472
20MP0008877_abnormal_DNA_methylation1.83896110
21MP0001672_abnormal_embryogenesis/_devel1.73315541
22MP0005380_embryogenesis_phenotype1.73315541
23MP0001697_abnormal_embryo_size1.71497477
24MP0010307_abnormal_tumor_latency1.67896419
25MP0000490_abnormal_crypts_of1.62612141
26MP0003984_embryonic_growth_retardation1.59880291
27MP0002102_abnormal_ear_morphology1.58093022
28MP0002088_abnormal_embryonic_growth/wei1.55194532
29MP0003567_abnormal_fetal_cardiomyocyte1.54084328
30MP0002080_prenatal_lethality1.53652731
31MP0000372_irregular_coat_pigmentation1.47110389
32MP0002019_abnormal_tumor_incidence1.39491009
33MP0000313_abnormal_cell_death1.39345894
34MP0001545_abnormal_hematopoietic_system1.34779602
35MP0005397_hematopoietic_system_phenotyp1.34779602
36MP0005410_abnormal_fertilization1.34758402
37MP0004808_abnormal_hematopoietic_stem1.34528726
38MP0002086_abnormal_extraembryonic_tissu1.34125992
39MP0004197_abnormal_fetal_growth/weight/1.31009785
40MP0002085_abnormal_embryonic_tissue1.30601681
41MP0003950_abnormal_plasma_membrane1.30315669
42MP0003186_abnormal_redox_activity1.28084772
43MP0002084_abnormal_developmental_patter1.21079284
44MP0003221_abnormal_cardiomyocyte_apopto1.17266306
45MP0002210_abnormal_sex_determination1.15568240
46MP0003763_abnormal_thymus_physiology1.15562950
47MP0002398_abnormal_bone_marrow1.08490615
48MP0001293_anophthalmia1.05415749
49MP0002722_abnormal_immune_system1.04883918
50MP0002163_abnormal_gland_morphology1.03185244
51MP0004147_increased_porphyrin_level1.01695940
52MP0005076_abnormal_cell_differentiation1.01498858
53MP0001145_abnormal_male_reproductive1.00482973
54MP0000358_abnormal_cell_content/1.00346910
55MP0000689_abnormal_spleen_morphology0.98837015
56MP0008995_early_reproductive_senescence0.98487658
57MP0001853_heart_inflammation0.97485663
58MP0000858_altered_metastatic_potential0.97183072
59MP0000703_abnormal_thymus_morphology0.95709148
60MP0005084_abnormal_gallbladder_morpholo0.93775181
61MP0008789_abnormal_olfactory_epithelium0.90247408
62MP0005379_endocrine/exocrine_gland_phen0.89717287
63MP0001764_abnormal_homeostasis0.89390556
64MP0002429_abnormal_blood_cell0.89329312
65MP0005023_abnormal_wound_healing0.88950944
66MP0006072_abnormal_retinal_apoptosis0.88193661
67MP0001929_abnormal_gametogenesis0.87616480
68MP0005408_hypopigmentation0.87406433
69MP0001835_abnormal_antigen_presentation0.87350631
70MP0000653_abnormal_sex_gland0.84687603
71MP0002132_abnormal_respiratory_system0.84629092
72MP0003315_abnormal_perineum_morphology0.84302263
73MP0005384_cellular_phenotype0.83808862
74MP0002254_reproductive_system_inflammat0.83361015
75MP0002938_white_spotting0.83316069
76MP0001727_abnormal_embryo_implantation0.82691881
77MP0005075_abnormal_melanosome_morpholog0.82212273
78MP0005621_abnormal_cell_physiology0.81092628
79MP0009697_abnormal_copulation0.80334860
80MP0003566_abnormal_cell_adhesion0.80313786
81MP0008260_abnormal_autophagy0.80158061
82MP0003698_abnormal_male_reproductive0.79735160
83MP0006036_abnormal_mitochondrial_physio0.79100681
84MP0003436_decreased_susceptibility_to0.78939140
85MP0003121_genomic_imprinting0.78831172
86MP0001529_abnormal_vocalization0.78672403
87MP0000716_abnormal_immune_system0.78558053
88MP0001661_extended_life_span0.77735062
89MP0001119_abnormal_female_reproductive0.77667596
90MP0009672_abnormal_birth_weight0.77220062
91MP0000750_abnormal_muscle_regeneration0.76221760
92MP0001188_hyperpigmentation0.75926226
93MP0001881_abnormal_mammary_gland0.75736026
94MP0002160_abnormal_reproductive_system0.74317262
95MP0004264_abnormal_extraembryonic_tissu0.74274296
96MP0001542_abnormal_bone_strength0.74184055
97MP0006054_spinal_hemorrhage0.73521545
98MP0001286_abnormal_eye_development0.73321386
99MP0003890_abnormal_embryonic-extraembry0.73012754
100MP0002234_abnormal_pharynx_morphology0.72780316
101MP0003937_abnormal_limbs/digits/tail_de0.72242517
102MP0004084_abnormal_cardiac_muscle0.71996702
103MP0003699_abnormal_female_reproductive0.71673004
104MP0005671_abnormal_response_to0.71380475
105MP0010030_abnormal_orbit_morphology0.71266223
106MP0003448_altered_tumor_morphology0.71156699
107MP0005501_abnormal_skin_physiology0.69632303
108MP0008873_increased_physiological_sensi0.68467545
109MP0001800_abnormal_humoral_immune0.67766514
110MP0002877_abnormal_melanocyte_morpholog0.67703371
111MP0002161_abnormal_fertility/fecundity0.67553594
112MP0002452_abnormal_antigen_presenting0.66958660
113MP0002111_abnormal_tail_morphology0.66009803
114MP0005389_reproductive_system_phenotype0.65371141
115MP0000647_abnormal_sebaceous_gland0.65256424
116MP0002420_abnormal_adaptive_immunity0.64529521
117MP0001819_abnormal_immune_cell0.63688629
118MP0002723_abnormal_immune_serum0.61364705
119MP0005395_other_phenotype0.61342766
120MP0002006_tumorigenesis0.60608083
121MP0003941_abnormal_skin_development0.60360213
122MP0002405_respiratory_system_inflammati0.60156739
123MP0005266_abnormal_metabolism0.59502932
124MP0009785_altered_susceptibility_to0.59445500
125MP0009053_abnormal_anal_canal0.58680529
126MP0003656_abnormal_erythrocyte_physiolo0.57941093
127MP0005000_abnormal_immune_tolerance0.57299429
128MP0009703_decreased_birth_body0.55403784
129MP0003943_abnormal_hepatobiliary_system0.55295887
130MP0002233_abnormal_nose_morphology0.55260316
131MP0006035_abnormal_mitochondrial_morpho0.54847447
132MP0002269_muscular_atrophy0.54694572
133MP0000477_abnormal_intestine_morphology0.53821342
134MP0002933_joint_inflammation0.53339539
135MP0001243_abnormal_dermal_layer0.52926226
136MP0000465_gastrointestinal_hemorrhage0.52666334
137MP0004782_abnormal_surfactant_physiolog0.52620473
138MP0002796_impaired_skin_barrier0.49651645
139MP0000627_abnormal_mammary_gland0.47852911

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.61333551
2Carpal bone hypoplasia (HP:0001498)4.31451759
3Breast hypoplasia (HP:0003187)4.09559747
4Irregular epiphyses (HP:0010582)4.07760256
5Acute necrotizing encephalopathy (HP:0006965)4.02001849
6Increased hepatocellular lipid droplets (HP:0006565)3.75679228
7Rough bone trabeculation (HP:0100670)3.75406524
8Acute encephalopathy (HP:0006846)3.66820164
9Abnormality of the anterior horn cell (HP:0006802)3.62536561
10Degeneration of anterior horn cells (HP:0002398)3.62536561
11Abnormal mitochondria in muscle tissue (HP:0008316)3.60563024
12Increased CSF lactate (HP:0002490)3.53475771
13Oral leukoplakia (HP:0002745)3.50649738
14Mitochondrial inheritance (HP:0001427)3.43531479
15Cerebral hypomyelination (HP:0006808)3.36516371
16Abnormality of cells of the erythroid lineage (HP:0012130)3.28036288
17Lipid accumulation in hepatocytes (HP:0006561)3.26388485
18Reticulocytopenia (HP:0001896)3.25559361
19Progressive macrocephaly (HP:0004481)3.25165000
20Increased serum pyruvate (HP:0003542)3.24335453
21Patellar aplasia (HP:0006443)3.21707873
22Abnormal number of erythroid precursors (HP:0012131)3.19863673
23Aplastic anemia (HP:0001915)3.16517042
24Selective tooth agenesis (HP:0001592)3.15967410
25Aplasia/Hypoplasia of the patella (HP:0006498)3.05759264
26Cerebral edema (HP:0002181)3.02526762
27Abnormality of glycolysis (HP:0004366)2.99329973
28Increased serum lactate (HP:0002151)2.97745283
29Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.84346250
30Renal Fanconi syndrome (HP:0001994)2.84324104
31Abnormal trabecular bone morphology (HP:0100671)2.81531248
32Abnormality of methionine metabolism (HP:0010901)2.80477144
33Hepatocellular necrosis (HP:0001404)2.78385183
34Colon cancer (HP:0003003)2.78071885
35Microvesicular hepatic steatosis (HP:0001414)2.77019791
36Impulsivity (HP:0100710)2.74673390
37Small epiphyses (HP:0010585)2.71891179
38Abnormal lung lobation (HP:0002101)2.71641688
39Chromsome breakage (HP:0040012)2.69816943
40Abnormality of the preputium (HP:0100587)2.68861455
41Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.68568577
42Decreased activity of mitochondrial respiratory chain (HP:0008972)2.67514335
43Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.67514335
44Meckel diverticulum (HP:0002245)2.67185411
45Microretrognathia (HP:0000308)2.64059203
46Abnormality of chromosome stability (HP:0003220)2.64010273
47Multiple enchondromatosis (HP:0005701)2.60889140
48Hepatic necrosis (HP:0002605)2.60797079
49Reduced antithrombin III activity (HP:0001976)2.58463280
50Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.58151494
51Absent epiphyses (HP:0010577)2.58151494
52Agnosia (HP:0010524)2.57717752
53Hypoplasia of the capital femoral epiphysis (HP:0003090)2.56153495
54Lactic acidosis (HP:0003128)2.53607576
55Abnormality of the ileum (HP:0001549)2.52975245
56Macrocytic anemia (HP:0001972)2.52448067
57Trismus (HP:0000211)2.47061896
58Nephroblastoma (Wilms tumor) (HP:0002667)2.46523213
59Chromosomal breakage induced by crosslinking agents (HP:0003221)2.46048066
60Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.43945366
61Premature graying of hair (HP:0002216)2.43399594
62Flat capital femoral epiphysis (HP:0003370)2.38217832
63Increased intramyocellular lipid droplets (HP:0012240)2.36745117
64Medulloblastoma (HP:0002885)2.34721468
65Bone marrow hypocellularity (HP:0005528)2.34579510
66Exercise intolerance (HP:0003546)2.34576742
67Embryonal renal neoplasm (HP:0011794)2.34557240
68Abnormality of aspartate family amino acid metabolism (HP:0010899)2.33768507
69Absent radius (HP:0003974)2.33641835
70Glossoptosis (HP:0000162)2.33091331
71Abnormality of the pons (HP:0007361)2.31491962
72Entropion (HP:0000621)2.31435577
73Secondary amenorrhea (HP:0000869)2.29982850
74Abnormality of the umbilical cord (HP:0010881)2.29980412
75Myelodysplasia (HP:0002863)2.29623096
76Respiratory difficulties (HP:0002880)2.29372150
77Exertional dyspnea (HP:0002875)2.28872922
78Premature ovarian failure (HP:0008209)2.28346610
79Aplasia/Hypoplasia of the uvula (HP:0010293)2.27967653
80Delayed epiphyseal ossification (HP:0002663)2.27133557
81Volvulus (HP:0002580)2.27108119
82Abnormal protein glycosylation (HP:0012346)2.23429289
83Abnormal glycosylation (HP:0012345)2.23429289
84Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.23429289
85Abnormal protein N-linked glycosylation (HP:0012347)2.23429289
86Neoplasm of the pancreas (HP:0002894)2.22245098
87Absent thumb (HP:0009777)2.21891911
88Methylmalonic acidemia (HP:0002912)2.20197815
89Muscle fiber atrophy (HP:0100295)2.18507423
90Abnormality of the duodenum (HP:0002246)2.16450827
91Progressive muscle weakness (HP:0003323)2.15908749
92Progressive external ophthalmoplegia (HP:0000590)2.15139598
93Abnormality of serum amino acid levels (HP:0003112)2.15012126
94Pallor (HP:0000980)2.14048942
95Duodenal stenosis (HP:0100867)2.09961558
96Small intestinal stenosis (HP:0012848)2.09961558
97Absent forearm bone (HP:0003953)2.09644835
98Aplasia involving forearm bones (HP:0009822)2.09644835
99Thrombocytosis (HP:0001894)2.09590601
100Respiratory failure (HP:0002878)2.07752029
101Pancreatic islet-cell hyperplasia (HP:0004510)2.07231807
102Type 2 muscle fiber atrophy (HP:0003554)2.06085564
103Sparse eyelashes (HP:0000653)2.06074831
104Ependymoma (HP:0002888)2.03781681
105Spinal muscular atrophy (HP:0007269)2.03287277
106Abnormality of the labia minora (HP:0012880)2.03147495
107Stillbirth (HP:0003826)2.02786483
108Ureteral duplication (HP:0000073)2.02697429
109Leukodystrophy (HP:0002415)2.02628340
110Megaloblastic anemia (HP:0001889)2.02173329
111Cleft eyelid (HP:0000625)2.01910922
112CNS hypomyelination (HP:0003429)2.01530651
113Hypoplasia of the pons (HP:0012110)2.00344521
114Cellular immunodeficiency (HP:0005374)1.99095198
115Poor head control (HP:0002421)1.98379515
116Atrophy/Degeneration involving motor neurons (HP:0007373)1.98030814
117Genu varum (HP:0002970)1.96183869
118Sloping forehead (HP:0000340)1.95118441
119Neoplasm of the colon (HP:0100273)1.94325131
120Rhabdomyosarcoma (HP:0002859)1.92186124
12111 pairs of ribs (HP:0000878)1.91470329
122Horseshoe kidney (HP:0000085)1.91153074
123IgM deficiency (HP:0002850)1.89883490
124Atresia of the external auditory canal (HP:0000413)1.89549481
125Lymphoma (HP:0002665)1.89358695
126Patent foramen ovale (HP:0001655)1.87856982
127Abnormal spermatogenesis (HP:0008669)1.86593612
128Deviation of the thumb (HP:0009603)1.86103565
129Glioma (HP:0009733)1.85788213
130Type I transferrin isoform profile (HP:0003642)1.84937582
131Slender long bone (HP:0003100)1.83979728
132Optic disc pallor (HP:0000543)1.83576391
133Amniotic constriction ring (HP:0009775)1.82848375
134Abnormality of placental membranes (HP:0011409)1.82848375
135Postnatal microcephaly (HP:0005484)1.82546557
1363-Methylglutaconic aciduria (HP:0003535)1.80120190
137Proximal placement of thumb (HP:0009623)1.79961046
138Tracheoesophageal fistula (HP:0002575)1.79576356
139Neoplasm of the adrenal gland (HP:0100631)1.79313656
140Abnormal number of incisors (HP:0011064)1.78669635
141Pancytopenia (HP:0001876)1.78490896
142Lethargy (HP:0001254)1.78148445
143Hyperglycinemia (HP:0002154)1.77966829
144Increased nuchal translucency (HP:0010880)1.77029438
145Squamous cell carcinoma (HP:0002860)1.76679150
146Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.76003736
147Abnormality of alanine metabolism (HP:0010916)1.76003736
148Hyperalaninemia (HP:0003348)1.76003736
149Metaphyseal cupping (HP:0003021)1.75782393
150Sensory axonal neuropathy (HP:0003390)1.75754526
151Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.75573948
152Abnormality of femoral epiphyses (HP:0006499)1.75573948
153Ectopic kidney (HP:0000086)1.75249393
154Aseptic necrosis (HP:0010885)1.74847382
155Amaurosis fugax (HP:0100576)1.73419467
156Abnormality of the epiphysis of the femoral head (HP:0010574)1.73149863
157Triphalangeal thumb (HP:0001199)1.72864165

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.98847368
2WEE14.46794533
3EIF2AK13.82153759
4BRSK23.14038108
5CDC73.06870424
6VRK22.66368500
7TSSK62.51936500
8ACVR1B2.49951718
9NEK22.48751102
10EIF2AK32.47658029
11SRPK12.41731866
12NME22.39671409
13PLK42.39292444
14TRIM282.15418264
15TTK2.15081443
16STK162.02307306
17NUAK11.99749149
18PLK11.93944883
19NEK11.87066125
20PLK31.80628513
21MKNK11.70540954
22BRSK11.65275301
23PIM21.64371591
24TESK21.55736086
25RPS6KA41.55042878
26DYRK31.54934219
27AURKB1.54134655
28CDK71.44588925
29VRK11.44341029
30STK101.42816496
31MKNK21.41535754
32ATR1.38309915
33EPHA21.36907631
34MAP3K81.35608984
35RPS6KB21.33521405
36TNIK1.31579051
37PASK1.28036786
38TAF11.24083244
39CHEK21.22816668
40CDK41.17629080
41AURKA1.13993346
42PBK1.12022911
43CHEK11.04627411
44STK31.03091541
45BMPR1B1.03018878
46PIM10.92855962
47MAP4K20.92008374
48TAOK20.90623103
49ERBB30.90600298
50SCYL20.90314723
51EIF2AK20.88837411
52ZAK0.88245242
53PNCK0.88244633
54TGFBR10.87976025
55MAP3K30.87492117
56CLK10.85059130
57PAK40.84936527
58STK40.83682080
59CDK120.83378372
60TESK10.82491171
61MST40.82058251
62MAP4K10.79923913
63FLT30.77426111
64CCNB10.76297260
65TLK10.74300171
66ALK0.73954954
67MARK30.73852672
68STK38L0.72252556
69MELK0.72089922
70CDK20.68519935
71KDR0.67881871
72ATM0.66033745
73CSNK2A20.65127513
74CSNK2A10.65037692
75MAP2K30.63880272
76BMPR20.62213969
77PAK10.62143526
78NME10.61272377
79ZAP700.60962931
80CDK80.60158363
81BCKDK0.58611987
82MAP3K120.56847998
83MAP3K110.56609348
84STK240.56335040
85CDK30.56011920
86CSNK1E0.54879991
87LRRK20.54403872
88WNK30.53570236
89PDK30.53448651
90PDK40.53448651
91DAPK10.50965344
92BRAF0.49837138
93CSNK1G10.48691798
94PLK20.47768061
95PRKCI0.47354407
96NLK0.46443647
97RPS6KA50.45823009
98CDK10.44789611
99IRAK30.44289098
100FGFR10.44206488
101TEC0.43115526
102MAP3K50.42859867
103PDK20.42596960
104IKBKB0.41507316
105ERBB40.38566556
106CDK90.38170966
107CSNK1G30.37428069
108CDK190.37190554
109EEF2K0.35907541
110CDK60.34355244
111PRKDC0.34347754
112STK390.34314516
113RAF10.33956052
114JAK30.33797409
115BCR0.32309102
116NEK90.32285850
117ABL20.31143602
118LIMK10.30535342
119TXK0.30315223
120BRD40.29818418
121MAPKAPK20.29299070
122PAK20.28417412
123CHUK0.27727805
124ILK0.26514152
125MAPKAPK30.26060267
126BTK0.25776004
127GRK10.24903366
128PIK3CG0.23959024
129CSNK1A1L0.21755884
130AKT20.21556259
131OXSR10.21338969

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.34863042
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.07838230
3RNA polymerase_Homo sapiens_hsa030203.79081954
4Proteasome_Homo sapiens_hsa030503.70318478
5Mismatch repair_Homo sapiens_hsa034303.65090988
6RNA transport_Homo sapiens_hsa030133.22471193
7Ribosome_Homo sapiens_hsa030103.09043457
8Spliceosome_Homo sapiens_hsa030403.08837496
9Base excision repair_Homo sapiens_hsa034102.72158850
10Nucleotide excision repair_Homo sapiens_hsa034202.63940524
11Homologous recombination_Homo sapiens_hsa034402.59767170
12Cell cycle_Homo sapiens_hsa041102.58078874
13Pyrimidine metabolism_Homo sapiens_hsa002402.50178732
14One carbon pool by folate_Homo sapiens_hsa006702.37394566
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.34106620
16Basal transcription factors_Homo sapiens_hsa030222.06829102
17Oxidative phosphorylation_Homo sapiens_hsa001902.06240460
18Non-homologous end-joining_Homo sapiens_hsa034501.93943324
19RNA degradation_Homo sapiens_hsa030181.84146017
20Fanconi anemia pathway_Homo sapiens_hsa034601.83081465
21Vitamin B6 metabolism_Homo sapiens_hsa007501.76864113
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.65687347
23p53 signaling pathway_Homo sapiens_hsa041151.59596969
24Propanoate metabolism_Homo sapiens_hsa006401.40986298
25Purine metabolism_Homo sapiens_hsa002301.37592564
26Pyruvate metabolism_Homo sapiens_hsa006201.37507126
27Epstein-Barr virus infection_Homo sapiens_hsa051691.36212844
28mRNA surveillance pathway_Homo sapiens_hsa030151.35737772
29Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.26175863
30Folate biosynthesis_Homo sapiens_hsa007901.20469182
31Antigen processing and presentation_Homo sapiens_hsa046121.15635777
32Protein export_Homo sapiens_hsa030601.09317442
33Alzheimers disease_Homo sapiens_hsa050101.02096162
34Fatty acid elongation_Homo sapiens_hsa000621.01047321
35Herpes simplex infection_Homo sapiens_hsa051680.99874552
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.98521007
37Cysteine and methionine metabolism_Homo sapiens_hsa002700.98459906
38Pentose phosphate pathway_Homo sapiens_hsa000300.97966677
39Selenocompound metabolism_Homo sapiens_hsa004500.95565615
40Biosynthesis of amino acids_Homo sapiens_hsa012300.94085428
41Legionellosis_Homo sapiens_hsa051340.93143295
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.88458476
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.87737854
44Steroid biosynthesis_Homo sapiens_hsa001000.87704901
45Viral carcinogenesis_Homo sapiens_hsa052030.83099669
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.82297483
47Drug metabolism - other enzymes_Homo sapiens_hsa009830.79155447
48Oocyte meiosis_Homo sapiens_hsa041140.78913058
49Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77909267
50Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69634959
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.67632954
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64357353
53Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.61241719
54Glutathione metabolism_Homo sapiens_hsa004800.60577762
55Sulfur metabolism_Homo sapiens_hsa009200.59333496
56HTLV-I infection_Homo sapiens_hsa051660.58777146
57Carbon metabolism_Homo sapiens_hsa012000.58311105
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.57518190
59Sulfur relay system_Homo sapiens_hsa041220.55668281
60Systemic lupus erythematosus_Homo sapiens_hsa053220.54631595
61Regulation of autophagy_Homo sapiens_hsa041400.53447749
62NF-kappa B signaling pathway_Homo sapiens_hsa040640.51863683
63Thyroid cancer_Homo sapiens_hsa052160.51554437
64Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.50375408
65Measles_Homo sapiens_hsa051620.49255839
66Primary immunodeficiency_Homo sapiens_hsa053400.48477280
67NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48040928
68Fatty acid metabolism_Homo sapiens_hsa012120.47380095
69Apoptosis_Homo sapiens_hsa042100.46901669
70Huntingtons disease_Homo sapiens_hsa050160.46345974
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.44856778
72Graft-versus-host disease_Homo sapiens_hsa053320.44405373
732-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.44046316
74Small cell lung cancer_Homo sapiens_hsa052220.41232842
75Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.40712209
76Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.40675999
77Fructose and mannose metabolism_Homo sapiens_hsa000510.39524604
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.39171289
79N-Glycan biosynthesis_Homo sapiens_hsa005100.36784241
80Influenza A_Homo sapiens_hsa051640.36779076
81MicroRNAs in cancer_Homo sapiens_hsa052060.36612252
82Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.36578063
83Shigellosis_Homo sapiens_hsa051310.35378753
84Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34784465
85Intestinal immune network for IgA production_Homo sapiens_hsa046720.34742158
86Peroxisome_Homo sapiens_hsa041460.34596095
87Hepatitis B_Homo sapiens_hsa051610.33641765
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33430236
89Butanoate metabolism_Homo sapiens_hsa006500.33287436
90Hematopoietic cell lineage_Homo sapiens_hsa046400.32462912
91Cardiac muscle contraction_Homo sapiens_hsa042600.31767576
92RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.31594146
93Galactose metabolism_Homo sapiens_hsa000520.30858797
94TGF-beta signaling pathway_Homo sapiens_hsa043500.30015269
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29342227
96Metabolic pathways_Homo sapiens_hsa011000.28820136
97Renin-angiotensin system_Homo sapiens_hsa046140.28377622
98Allograft rejection_Homo sapiens_hsa053300.27942005
99HIF-1 signaling pathway_Homo sapiens_hsa040660.25983720
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.25959420
101Asthma_Homo sapiens_hsa053100.25214639
102Fatty acid degradation_Homo sapiens_hsa000710.24212549
103Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.21176302
104Leishmaniasis_Homo sapiens_hsa051400.20795653
105Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.20767498
106Fatty acid biosynthesis_Homo sapiens_hsa000610.20180897
107Type I diabetes mellitus_Homo sapiens_hsa049400.20059078
108Transcriptional misregulation in cancer_Homo sapiens_hsa052020.20012947
109Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.19773832
110Lysine degradation_Homo sapiens_hsa003100.19674473
111Vitamin digestion and absorption_Homo sapiens_hsa049770.19486388
112Parkinsons disease_Homo sapiens_hsa050120.18946596
113Arginine and proline metabolism_Homo sapiens_hsa003300.18827957
114Hippo signaling pathway_Homo sapiens_hsa043900.18618593
115SNARE interactions in vesicular transport_Homo sapiens_hsa041300.18498577
116Arachidonic acid metabolism_Homo sapiens_hsa005900.16908270
117Colorectal cancer_Homo sapiens_hsa052100.14394589
118Tryptophan metabolism_Homo sapiens_hsa003800.13642409
119beta-Alanine metabolism_Homo sapiens_hsa004100.13469885
120Central carbon metabolism in cancer_Homo sapiens_hsa052300.12758325
121Jak-STAT signaling pathway_Homo sapiens_hsa046300.11457828
122Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.11311487
123Viral myocarditis_Homo sapiens_hsa054160.11221068
124Acute myeloid leukemia_Homo sapiens_hsa052210.11200725
125Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.08597216
126Olfactory transduction_Homo sapiens_hsa047400.07811394
127Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.07346085
128Maturity onset diabetes of the young_Homo sapiens_hsa049500.04944456
129Caffeine metabolism_Homo sapiens_hsa002320.03980405
130Autoimmune thyroid disease_Homo sapiens_hsa053200.01211522

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