LYPD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nonmotile primary cilium assembly (GO:0035058)6.28497052
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.63687690
3vocalization behavior (GO:0071625)5.40984294
4ionotropic glutamate receptor signaling pathway (GO:0035235)5.38943803
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.32714120
6neuron cell-cell adhesion (GO:0007158)5.28567807
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.28500892
8locomotory exploration behavior (GO:0035641)5.24892667
9synaptic vesicle exocytosis (GO:0016079)5.03588649
10regulation of glutamate receptor signaling pathway (GO:1900449)5.00075138
11synaptic vesicle maturation (GO:0016188)4.98353239
12positive regulation of vascular permeability (GO:0043117)4.97503398
13protein localization to synapse (GO:0035418)4.89257851
14glutamate receptor signaling pathway (GO:0007215)4.82334189
15pyrimidine nucleobase catabolic process (GO:0006208)4.76624071
16positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.73931853
17regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.72200600
18regulation of synaptic vesicle exocytosis (GO:2000300)4.60589421
19synaptic transmission, glutamatergic (GO:0035249)4.55224215
20lens fiber cell development (GO:0070307)4.47258855
21glutamate secretion (GO:0014047)4.45217159
22exploration behavior (GO:0035640)4.41462220
23neuronal action potential propagation (GO:0019227)4.39017999
24neuron-neuron synaptic transmission (GO:0007270)4.38312763
25regulation of long-term neuronal synaptic plasticity (GO:0048169)4.34278636
26regulation of neuronal synaptic plasticity (GO:0048168)4.29312156
27regulation of synaptic vesicle transport (GO:1902803)4.21220489
28behavioral response to nicotine (GO:0035095)4.20341534
29eye photoreceptor cell differentiation (GO:0001754)4.03799913
30photoreceptor cell differentiation (GO:0046530)4.03799913
31presynaptic membrane assembly (GO:0097105)4.02183620
32regulation of excitatory postsynaptic membrane potential (GO:0060079)4.00858845
33gamma-aminobutyric acid signaling pathway (GO:0007214)4.00229987
34neuron recognition (GO:0008038)3.99179828
35neurotransmitter secretion (GO:0007269)3.96394193
36long-term memory (GO:0007616)3.93041213
37transmission of nerve impulse (GO:0019226)3.88883946
38neurotransmitter-gated ion channel clustering (GO:0072578)3.87087312
39postsynaptic membrane organization (GO:0001941)3.82192615
40startle response (GO:0001964)3.81894670
41synaptic vesicle docking involved in exocytosis (GO:0016081)3.81385064
42regulation of postsynaptic membrane potential (GO:0060078)3.79638989
43neuronal stem cell maintenance (GO:0097150)3.76616126
44dendritic spine morphogenesis (GO:0060997)3.76298237
45nucleobase catabolic process (GO:0046113)3.75708202
46negative regulation of oligodendrocyte differentiation (GO:0048715)3.74865917
47presynaptic membrane organization (GO:0097090)3.74662422
48behavioral fear response (GO:0001662)3.69690504
49behavioral defense response (GO:0002209)3.69690504
50negative regulation of astrocyte differentiation (GO:0048712)3.69079262
51substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.68307508
52substrate-independent telencephalic tangential migration (GO:0021826)3.68307508
53positive regulation of Notch signaling pathway (GO:0045747)3.65143155
54vascular smooth muscle contraction (GO:0014829)3.64731711
55positive regulation of synaptic transmission, GABAergic (GO:0032230)3.64300725
56long-term synaptic potentiation (GO:0060291)3.63824180
57regulation of synaptic plasticity (GO:0048167)3.63528029
58negative regulation of synaptic transmission, GABAergic (GO:0032229)3.62615980
59positive regulation of membrane potential (GO:0045838)3.61725693
60response to histamine (GO:0034776)3.59792930
61regulation of synapse structural plasticity (GO:0051823)3.59543554
62regulation of dendritic spine morphogenesis (GO:0061001)3.56911523
63spinal cord development (GO:0021510)3.55993533
64pattern specification involved in kidney development (GO:0061004)3.51078831
65regulation of synaptic transmission, glutamatergic (GO:0051966)3.50829340
66G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.49628772
67regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.48304692
68regulation of glutamate secretion (GO:0014048)3.47137371
69axonal fasciculation (GO:0007413)3.46041312
70layer formation in cerebral cortex (GO:0021819)3.44888589
71membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.43558200
72positive regulation of synapse maturation (GO:0090129)3.43047714
73axon ensheathment in central nervous system (GO:0032291)3.42461575
74central nervous system myelination (GO:0022010)3.42461575
75fear response (GO:0042596)3.41231636
76cell proliferation in forebrain (GO:0021846)3.40834248
77astrocyte differentiation (GO:0048708)3.40813050
78artery smooth muscle contraction (GO:0014824)3.39349969
79neurotransmitter transport (GO:0006836)3.39064068
80limb bud formation (GO:0060174)3.38407931
81regulation of vesicle fusion (GO:0031338)3.36785041
82G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.36486438
83regulation of female receptivity (GO:0045924)3.35618960
84positive regulation of neurotransmitter secretion (GO:0001956)3.33338947
85innervation (GO:0060384)3.32666524
86synaptic vesicle endocytosis (GO:0048488)3.31984724
87negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.30968692
88tongue development (GO:0043586)3.30771346
89spliceosomal complex assembly (GO:0000245)3.30599100
90cholesterol biosynthetic process (GO:0006695)3.29157853
91learning (GO:0007612)3.28428905
92radial glial cell differentiation (GO:0060019)3.28330028
93female mating behavior (GO:0060180)3.27051861
94spinal cord association neuron differentiation (GO:0021527)3.26218667
95positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.24048208
96regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.22040647
97regulation of neurotransmitter secretion (GO:0046928)3.21019172
98membrane depolarization (GO:0051899)3.20216669
99camera-type eye morphogenesis (GO:0048593)3.19988604
100gamma-aminobutyric acid transport (GO:0015812)3.19913382
101cellular response to cholesterol (GO:0071397)3.19595778
102cellular potassium ion homeostasis (GO:0030007)3.15682167
103regulation of neurotransmitter levels (GO:0001505)3.15221235
104regulation of dendritic spine development (GO:0060998)3.14674483
105proline transport (GO:0015824)3.11971617
106calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.11784626
107positive regulation of synapse assembly (GO:0051965)3.08569337
108membrane hyperpolarization (GO:0060081)3.07821386
109auditory behavior (GO:0031223)3.07677734
110cerebral cortex radially oriented cell migration (GO:0021799)3.06831219
111synaptic transmission (GO:0007268)3.06050897
112sequestering of actin monomers (GO:0042989)3.05862898
113positive regulation of dendritic spine development (GO:0060999)3.04877149
114neuronal ion channel clustering (GO:0045161)3.04870632
115negative regulation of amino acid transport (GO:0051956)3.04869811
116positive regulation of neurotransmitter transport (GO:0051590)3.03837069
117somite development (GO:0061053)3.03328419
118regulation of synaptic transmission (GO:0050804)3.03313442
119regulation of cilium movement (GO:0003352)3.02602289
120synapse assembly (GO:0007416)3.00320958
121synaptic transmission, dopaminergic (GO:0001963)3.00233215
122regulation of synaptic transmission, GABAergic (GO:0032228)2.99829923
123serine family amino acid catabolic process (GO:0009071)2.99618118
124vesicle transport along microtubule (GO:0047496)2.98892803
125positive regulation of synaptic transmission (GO:0050806)2.98380033
126dendritic spine organization (GO:0097061)2.98363065
127regulation of neurotransmitter transport (GO:0051588)2.97776314
128regulation of synapse maturation (GO:0090128)2.97273213
129retinal ganglion cell axon guidance (GO:0031290)2.96509628
130cerebellar Purkinje cell differentiation (GO:0021702)2.96373388
131regulation of collateral sprouting (GO:0048670)2.96124776
132tonic smooth muscle contraction (GO:0014820)2.95836765
133response to auditory stimulus (GO:0010996)2.95694014
134hippocampus development (GO:0021766)2.95032009
135neuromuscular process controlling balance (GO:0050885)2.92035016
136smoothened signaling pathway (GO:0007224)2.91826625
137positive regulation of dendritic spine morphogenesis (GO:0061003)2.91431613
138prepulse inhibition (GO:0060134)2.90888068
139regulation of respiratory system process (GO:0044065)2.90400491
140chemosensory behavior (GO:0007635)2.90337216
141positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.87890372
142protein localization to cilium (GO:0061512)2.87706478
143cellular response to leptin stimulus (GO:0044320)2.85447067
144response to lipoprotein particle (GO:0055094)2.84489855
145sterol biosynthetic process (GO:0016126)2.84021368
146negative regulation of glial cell differentiation (GO:0045686)2.82425121
147central nervous system projection neuron axonogenesis (GO:0021952)2.78729081
148tachykinin receptor signaling pathway (GO:0007217)2.78159007
149appendage development (GO:0048736)2.77696933
150limb development (GO:0060173)2.77696933
151lateral sprouting from an epithelium (GO:0060601)2.76747889
152mechanosensory behavior (GO:0007638)2.75135628
153regulation of somitogenesis (GO:0014807)2.74406309
154cranial nerve morphogenesis (GO:0021602)2.73264159
155cilium morphogenesis (GO:0060271)2.71835282
156negative regulation of appetite (GO:0032099)2.71167404
157negative regulation of response to food (GO:0032096)2.71167404
158Notch signaling involved in heart development (GO:0061314)2.67794069
159ubiquinone metabolic process (GO:0006743)2.66707895
160oocyte development (GO:0048599)2.66313622
161forebrain neuron differentiation (GO:0021879)2.66149004
162epithelial cilium movement (GO:0003351)2.65163989
163regulation of oligodendrocyte differentiation (GO:0048713)2.63423479
164regulation of development, heterochronic (GO:0040034)2.62741252
165otic vesicle formation (GO:0030916)2.62612227
166establishment of mitochondrion localization (GO:0051654)2.62606815
167regulation of cholesterol biosynthetic process (GO:0045540)2.61608648
168auditory receptor cell differentiation (GO:0042491)2.61175207
169photoreceptor cell development (GO:0042461)2.59476980
170cellular response to follicle-stimulating hormone stimulus (GO:0071372)2.59437440
171isoprenoid biosynthetic process (GO:0008299)2.58099712
172negative regulation of smoothened signaling pathway (GO:0045879)2.57219118
173intraciliary transport (GO:0042073)2.57164298
174positive regulation of oligodendrocyte differentiation (GO:0048714)2.56759905
175hypothalamus development (GO:0021854)2.53867933
176regulation of hippo signaling (GO:0035330)2.53435955
177neuron fate determination (GO:0048664)2.53431201
178cysteine metabolic process (GO:0006534)2.52860205
179oligodendrocyte differentiation (GO:0048709)2.52691226
180endocardial cushion morphogenesis (GO:0003203)2.52633908
181Sertoli cell development (GO:0060009)2.52455900

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.12545984
2GBX2_23144817_ChIP-Seq_PC3_Human4.13195290
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.60069230
4* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.23148466
5* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.21250261
6* SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.11115470
7* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.76874200
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.70741984
9* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.70741984
10* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.70416283
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.67871421
12EZH2_27304074_Chip-Seq_ESCs_Mouse2.66172201
13* REST_21632747_ChIP-Seq_MESCs_Mouse2.59266278
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.52615028
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.52597061
16* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.44191138
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.42240360
18TAF15_26573619_Chip-Seq_HEK293_Human2.29334716
19RARB_27405468_Chip-Seq_BRAIN_Mouse2.27715998
20* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.26950150
21* EZH2_27294783_Chip-Seq_ESCs_Mouse2.23731177
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.23197810
23* RNF2_27304074_Chip-Seq_ESCs_Mouse2.19571582
24CTBP2_25329375_ChIP-Seq_LNCAP_Human2.10934653
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.08206499
26CTBP1_25329375_ChIP-Seq_LNCAP_Human2.06916983
27IKZF1_21737484_ChIP-ChIP_HCT116_Human2.04453955
28DROSHA_22980978_ChIP-Seq_HELA_Human2.02473135
29REST_18959480_ChIP-ChIP_MESCs_Mouse2.02079558
30ZFP57_27257070_Chip-Seq_ESCs_Mouse2.01047949
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.00955087
32NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.88737767
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.82401203
34SMAD4_21799915_ChIP-Seq_A2780_Human1.76374875
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.75696263
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.74877003
37* P300_19829295_ChIP-Seq_ESCs_Human1.73166795
38SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.66533230
39AR_21572438_ChIP-Seq_LNCaP_Human1.66069759
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.61469382
41PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.58516262
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.56513998
43TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.50528672
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.49031588
45MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.46622442
46RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46143969
47FUS_26573619_Chip-Seq_HEK293_Human1.46099023
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.41674071
49ESR1_20079471_ChIP-ChIP_T-47D_Human1.40320860
50SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39395763
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38815757
52EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.38092130
53IGF1R_20145208_ChIP-Seq_DFB_Human1.36973298
54ERG_21242973_ChIP-ChIP_JURKAT_Human1.36655983
55RNF2_27304074_Chip-Seq_NSC_Mouse1.36425531
56OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.36263381
57* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.35854439
58AR_25329375_ChIP-Seq_VCAP_Human1.33152401
59* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31839726
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.31525054
61NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.31146109
62VDR_22108803_ChIP-Seq_LS180_Human1.31003099
63CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.30147202
64NR3C1_23031785_ChIP-Seq_PC12_Mouse1.27845643
65ZNF274_21170338_ChIP-Seq_K562_Hela1.25011340
66SOX2_21211035_ChIP-Seq_LN229_Gbm1.24954585
67* RING1B_27294783_Chip-Seq_ESCs_Mouse1.24013202
68STAT3_23295773_ChIP-Seq_U87_Human1.22016454
69UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21303127
70TRIM28_21343339_ChIP-Seq_HEK293_Human1.20708805
71ER_23166858_ChIP-Seq_MCF-7_Human1.18400186
72TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17747101
73PRDM14_20953172_ChIP-Seq_ESCs_Human1.15415647
74EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.15249184
75CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14178394
76KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12868960
77P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12006013
78SMAD_19615063_ChIP-ChIP_OVARY_Human1.11388542
79TCF4_23295773_ChIP-Seq_U87_Human1.11063269
80STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.11006492
81* JUN_21703547_ChIP-Seq_K562_Human1.10790061
82RUNX2_22187159_ChIP-Seq_PCA_Human1.10206283
83* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09691450
84* NANOG_18555785_Chip-Seq_ESCs_Mouse1.09263915
85LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09133240
86EP300_21415370_ChIP-Seq_HL-1_Mouse1.09111917
87CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08404187
88TP53_20018659_ChIP-ChIP_R1E_Mouse1.07998163
89RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.07055366
90* RING1B_27294783_Chip-Seq_NPCs_Mouse1.05864706
91AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.05731157
92EWS_26573619_Chip-Seq_HEK293_Human1.04801735
93NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04790648
94CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.04529592
95CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.03504139
96ARNT_22903824_ChIP-Seq_MCF-7_Human1.03453527
97RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.03127261
98AR_19668381_ChIP-Seq_PC3_Human1.02943129
99POU5F1_16153702_ChIP-ChIP_HESCs_Human1.02874643
100TP53_16413492_ChIP-PET_HCT116_Human1.01654499
101MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00784830
102TP53_18474530_ChIP-ChIP_U2OS_Human1.00602339
103TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.99648069
104POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.99189117
105SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.98723985
106AHR_22903824_ChIP-Seq_MCF-7_Human0.96318882
107TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96266687
108POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96266687
109* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95930431
110TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93898455
111* E2F1_18555785_Chip-Seq_ESCs_Mouse0.93771249
112* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.92204498
113SOX2_18555785_ChIP-Seq_MESCs_Mouse0.92164402
114WT1_25993318_ChIP-Seq_PODOCYTE_Human0.91546656
115* P53_22387025_ChIP-Seq_ESCs_Mouse0.91141108
116SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.90863518
117POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.90406927
118ZNF217_24962896_ChIP-Seq_MCF-7_Human0.90366909
119MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.90209183
120* PCGF2_27294783_Chip-Seq_ESCs_Mouse0.89171021
121KDM2B_26808549_Chip-Seq_REH_Human0.88623622
122SMAD3_21741376_ChIP-Seq_ESCs_Human0.87665109
123* CMYC_18555785_Chip-Seq_ESCs_Mouse0.87444735
124MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.87318312
125BCAT_22108803_ChIP-Seq_LS180_Human0.87254731
126IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.86765342
127CBP_20019798_ChIP-Seq_JUKART_Human0.86765342
128* PCGF2_27294783_Chip-Seq_NPCs_Mouse0.86501379
129TBX3_20139965_ChIP-Seq_MESCs_Mouse0.85932862
130TBX3_20139965_ChIP-Seq_ESCs_Mouse0.85367814
131FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.81053243
132CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.79441251
133SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.77717578
134SOX9_26525672_Chip-Seq_HEART_Mouse0.76092318
135POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.75799296

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.12026611
2MP0003880_abnormal_central_pattern5.69291268
3* MP0003635_abnormal_synaptic_transmissio4.08061690
4MP0003136_yellow_coat_color3.89702830
5MP0000566_synostosis3.76605279
6MP0009745_abnormal_behavioral_response3.53015983
7MP0004270_analgesia3.47777955
8* MP0002063_abnormal_learning/memory/cond3.33237348
9MP0003183_abnormal_peptide_metabolism3.18380273
10MP0002064_seizures3.15660565
11MP0001968_abnormal_touch/_nociception2.98247782
12* MP0002572_abnormal_emotion/affect_behav2.88456115
13MP0009046_muscle_twitch2.78534075
14MP0005423_abnormal_somatic_nervous2.77394248
15MP0002272_abnormal_nervous_system2.69770307
16MP0001486_abnormal_startle_reflex2.64577577
17MP0002822_catalepsy2.60778617
18MP0008789_abnormal_olfactory_epithelium2.54553886
19MP0002736_abnormal_nociception_after2.47912625
20MP0003011_delayed_dark_adaptation2.42512130
21MP0002734_abnormal_mechanical_nocicepti2.41732302
22MP0001501_abnormal_sleep_pattern2.41411291
23MP0001440_abnormal_grooming_behavior2.30658345
24MP0002735_abnormal_chemical_nociception2.29900812
25MP0006276_abnormal_autonomic_nervous2.19912205
26MP0001529_abnormal_vocalization2.19341064
27MP0002282_abnormal_trachea_morphology2.05910343
28MP0010030_abnormal_orbit_morphology2.02595102
29MP0005645_abnormal_hypothalamus_physiol1.98996234
30MP0002067_abnormal_sensory_capabilities1.94605363
31MP0000778_abnormal_nervous_system1.94552278
32MP0001970_abnormal_pain_threshold1.92721496
33MP0002733_abnormal_thermal_nociception1.91620782
34MP0005646_abnormal_pituitary_gland1.88984161
35MP0002184_abnormal_innervation1.84684545
36MP0001188_hyperpigmentation1.82417501
37MP0002653_abnormal_ependyma_morphology1.81292233
38MP0002557_abnormal_social/conspecific_i1.77805010
39MP0004924_abnormal_behavior1.71601875
40MP0005386_behavior/neurological_phenoty1.71601875
41MP0001905_abnormal_dopamine_level1.69035411
42MP0005257_abnormal_intraocular_pressure1.65023157
43MP0003787_abnormal_imprinting1.62899756
44MP0002938_white_spotting1.62416439
45MP0002928_abnormal_bile_duct1.61314983
46MP0001984_abnormal_olfaction1.60278240
47MP0003879_abnormal_hair_cell1.60252612
48MP0009780_abnormal_chondrocyte_physiolo1.59033484
49MP0005248_abnormal_Harderian_gland1.57753829
50MP0000537_abnormal_urethra_morphology1.57563552
51MP0003119_abnormal_digestive_system1.53521397
52MP0003329_amyloid_beta_deposits1.53087038
53MP0004811_abnormal_neuron_physiology1.51527964
54MP0003122_maternal_imprinting1.50995095
55MP0005253_abnormal_eye_physiology1.47347875
56MP0003283_abnormal_digestive_organ1.47023937
57MP0004142_abnormal_muscle_tone1.45944816
58MP0008569_lethality_at_weaning1.43388681
59MP0000955_abnormal_spinal_cord1.42734985
60MP0002066_abnormal_motor_capabilities/c1.40052552
61MP0003385_abnormal_body_wall1.39797830
62MP0002882_abnormal_neuron_morphology1.39111890
63MP0001502_abnormal_circadian_rhythm1.39010021
64MP0004885_abnormal_endolymph1.38882745
65MP0000049_abnormal_middle_ear1.34789919
66MP0009053_abnormal_anal_canal1.33937517
67MP0001293_anophthalmia1.33270846
68MP0000428_abnormal_craniofacial_morphol1.31201359
69MP0002249_abnormal_larynx_morphology1.29929120
70MP0000534_abnormal_ureter_morphology1.28920051
71MP0001346_abnormal_lacrimal_gland1.27188587
72MP0004742_abnormal_vestibular_system1.25706240
73MP0002909_abnormal_adrenal_gland1.24417742
74MP0003942_abnormal_urinary_system1.22296159
75MP0004858_abnormal_nervous_system1.22090935
76MP0002233_abnormal_nose_morphology1.20040210
77MP0005195_abnormal_posterior_eye1.15495148
78MP0005409_darkened_coat_color1.15405771
79MP0005391_vision/eye_phenotype1.15083391
80MP0002234_abnormal_pharynx_morphology1.13853779
81MP0003633_abnormal_nervous_system1.12587430
82MP0010386_abnormal_urinary_bladder1.08984205
83MP0006292_abnormal_olfactory_placode1.08544805
84MP0002152_abnormal_brain_morphology1.06142066
85MP0000462_abnormal_digestive_system1.03722913
86MP0001963_abnormal_hearing_physiology1.02478089
87MP0003755_abnormal_palate_morphology1.01187180
88MP0000613_abnormal_salivary_gland1.00416337
89MP0003631_nervous_system_phenotype0.99318869
90MP0001958_emphysema0.98534934
91MP0004133_heterotaxia0.97778857
92MP0005647_abnormal_sex_gland0.96266199
93MP0002229_neurodegeneration0.96248732
94MP0002092_abnormal_eye_morphology0.96155621
95MP0002751_abnormal_autonomic_nervous0.95257739
96MP0008872_abnormal_physiological_respon0.94417514
97MP0002876_abnormal_thyroid_physiology0.93848756
98MP0001299_abnormal_eye_distance/0.93206873
99MP0005508_abnormal_skeleton_morphology0.92964353
100MP0001286_abnormal_eye_development0.92833158
101MP0000579_abnormal_nail_morphology0.92394036
102MP0000631_abnormal_neuroendocrine_gland0.92390459
103MP0001485_abnormal_pinna_reflex0.92371230
104MP0005551_abnormal_eye_electrophysiolog0.91661270
105MP0005499_abnormal_olfactory_system0.91121765
106MP0005394_taste/olfaction_phenotype0.91121765
107MP0002069_abnormal_eating/drinking_beha0.89505075
108MP0000920_abnormal_myelination0.88691673
109MP0005623_abnormal_meninges_morphology0.86360630
110MP0009250_abnormal_appendicular_skeleto0.86288876
111MP0002752_abnormal_somatic_nervous0.85328978
112MP0002837_dystrophic_cardiac_calcinosis0.83759817
113MP0000647_abnormal_sebaceous_gland0.82496386
114MP0002697_abnormal_eye_size0.80617127
115MP0005171_absent_coat_pigmentation0.80371332
116MP0001270_distended_abdomen0.80359494
117MP0000026_abnormal_inner_ear0.80147343
118MP0008874_decreased_physiological_sensi0.79819066
119MP0004085_abnormal_heartbeat0.79232096
120MP0001177_atelectasis0.78655573
121MP0003634_abnormal_glial_cell0.78031348
122MP0005535_abnormal_body_temperature0.77822261
123MP0004145_abnormal_muscle_electrophysio0.77638947
124MP0003075_altered_response_to0.73235022
125MP0001664_abnormal_digestion0.70755025
126MP0004484_altered_response_of0.69281026
127MP0000751_myopathy0.69029370
128MP0000013_abnormal_adipose_tissue0.68205827
129MP0003690_abnormal_glial_cell0.66838260
130MP0003632_abnormal_nervous_system0.66747661
131MP0005379_endocrine/exocrine_gland_phen0.65702442
132MP0002102_abnormal_ear_morphology0.62965824
133MP0003938_abnormal_ear_development0.61724463
134MP0003121_genomic_imprinting0.58812230
135MP0004215_abnormal_myocardial_fiber0.57635827
136MP0000604_amyloidosis0.55894690
137MP0002638_abnormal_pupillary_reflex0.55548053
138MP0001943_abnormal_respiration0.54092659
139MP0003861_abnormal_nervous_system0.53963307
140MP0003137_abnormal_impulse_conducting0.52990966
141MP0006072_abnormal_retinal_apoptosis0.51913334
142MP0008877_abnormal_DNA_methylation0.51500527
143MP0002090_abnormal_vision0.49587362
144MP0002163_abnormal_gland_morphology0.48961705
145MP0010770_preweaning_lethality0.47010165
146MP0002082_postnatal_lethality0.47010165

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.44572721
2Myokymia (HP:0002411)6.78586447
3Focal seizures (HP:0007359)5.86304715
4Vitreoretinal degeneration (HP:0000655)5.48295137
5Epileptic encephalopathy (HP:0200134)5.31725677
6Atonic seizures (HP:0010819)4.97818575
7Febrile seizures (HP:0002373)4.83388681
8Absence seizures (HP:0002121)4.49572526
9Visual hallucinations (HP:0002367)4.49128047
10Progressive cerebellar ataxia (HP:0002073)4.24737241
11Septo-optic dysplasia (HP:0100842)4.24108758
12Dialeptic seizures (HP:0011146)4.20434246
13Hyperventilation (HP:0002883)4.10158473
14Generalized tonic-clonic seizures (HP:0002069)3.87078690
15Broad-based gait (HP:0002136)3.86766226
16Rib fusion (HP:0000902)3.53093450
17Abnormality of the labia minora (HP:0012880)3.43046130
18Supranuclear gaze palsy (HP:0000605)3.39779671
19Abnormality of dentin (HP:0010299)3.22084578
20Anxiety (HP:0000739)3.14361027
21Poor eye contact (HP:0000817)3.11879023
22Amblyopia (HP:0000646)3.06247555
23True hermaphroditism (HP:0010459)3.05791443
24Dysmetria (HP:0001310)3.01787438
25Impaired vibration sensation in the lower limbs (HP:0002166)3.00724884
26Ankle clonus (HP:0011448)2.97395185
27Turricephaly (HP:0000262)2.96017514
28Neurofibrillary tangles (HP:0002185)2.95272979
29Action tremor (HP:0002345)2.93135597
30Gaze-evoked nystagmus (HP:0000640)2.90254592
31Oligodactyly (HP:0012165)2.88121107
32Truncal ataxia (HP:0002078)2.87566580
33Drooling (HP:0002307)2.85171722
34Excessive salivation (HP:0003781)2.85171722
35Anterior segment dysgenesis (HP:0007700)2.83462401
36Dyschromatopsia (HP:0007641)2.83165516
37Abnormality of the diencephalon (HP:0010662)2.82014704
38Lissencephaly (HP:0001339)2.78553807
39Molar tooth sign on MRI (HP:0002419)2.76668265
40Abnormality of midbrain morphology (HP:0002418)2.76668265
41Cerebral inclusion bodies (HP:0100314)2.76578048
42Broad distal phalanx of finger (HP:0009836)2.76130305
43Split foot (HP:0001839)2.72903299
44Absent rod-and cone-mediated responses on ERG (HP:0007688)2.71215743
45Progressive inability to walk (HP:0002505)2.70263018
46Abnormal eating behavior (HP:0100738)2.68285797
47Dysdiadochokinesis (HP:0002075)2.67979700
48Epileptiform EEG discharges (HP:0011182)2.64919305
49Maternal diabetes (HP:0009800)2.63136127
50Mutism (HP:0002300)2.60562493
51Impaired social interactions (HP:0000735)2.59485842
52Abnormal social behavior (HP:0012433)2.59485842
53Depression (HP:0000716)2.58270641
54Fetal akinesia sequence (HP:0001989)2.55678601
55Limb dystonia (HP:0002451)2.55308871
56Urinary bladder sphincter dysfunction (HP:0002839)2.54329497
57Coronal craniosynostosis (HP:0004440)2.50471877
58Pancreatic fibrosis (HP:0100732)2.47728382
59Postural instability (HP:0002172)2.47609576
60Oligodactyly (hands) (HP:0001180)2.47584921
61Gait imbalance (HP:0002141)2.45420049
62Diplopia (HP:0000651)2.44209701
63Abnormality of binocular vision (HP:0011514)2.44209701
64Polyphagia (HP:0002591)2.43594505
65EEG with generalized epileptiform discharges (HP:0011198)2.41187719
66Hemiparesis (HP:0001269)2.40125184
67Absent speech (HP:0001344)2.39376386
68Papilledema (HP:0001085)2.36950075
69Inability to walk (HP:0002540)2.35909442
70Cerebellar dysplasia (HP:0007033)2.32693595
71Pigmentary retinal degeneration (HP:0001146)2.32373505
72Poor coordination (HP:0002370)2.32005422
73Tubulointerstitial nephritis (HP:0001970)2.31096254
74Spastic gait (HP:0002064)2.30953133
75Absent septum pellucidum (HP:0001331)2.28470095
76Hyperglycinemia (HP:0002154)2.28371217
77Abolished electroretinogram (ERG) (HP:0000550)2.28343634
78Postaxial hand polydactyly (HP:0001162)2.28140047
79Neonatal short-limb short stature (HP:0008921)2.26972074
80Fibular hypoplasia (HP:0003038)2.26970794
81Scanning speech (HP:0002168)2.25254375
82Thickened helices (HP:0000391)2.25243985
83Abnormality of the corticospinal tract (HP:0002492)2.25139297
84Stereotypic behavior (HP:0000733)2.24695981
85Large eyes (HP:0001090)2.24180312
86Hypsarrhythmia (HP:0002521)2.23571122
87Bradykinesia (HP:0002067)2.23484006
88Aplasia/Hypoplasia of the fibula (HP:0006492)2.21370138
89Focal dystonia (HP:0004373)2.19763749
90Blue irides (HP:0000635)2.18308118
91Torticollis (HP:0000473)2.17034549
92Hemivertebrae (HP:0002937)2.15888414
93Protruding tongue (HP:0010808)2.14684304
94Preaxial foot polydactyly (HP:0001841)2.14662525
95Abnormality of the aortic arch (HP:0012303)2.13818668
96Keratoconus (HP:0000563)2.13589494
97Increased corneal curvature (HP:0100692)2.13589494
98Delusions (HP:0000746)2.13473780
99Postaxial foot polydactyly (HP:0001830)2.13123859
100Generalized myoclonic seizures (HP:0002123)2.12819188
101Aplasia/Hypoplasia of the brainstem (HP:0007362)2.11994025
102Hypoplasia of the brainstem (HP:0002365)2.11994025
103Congenital primary aphakia (HP:0007707)2.09973517
104Esophageal atresia (HP:0002032)2.09744567
105Broad foot (HP:0001769)2.09101094
106Medial flaring of the eyebrow (HP:0010747)2.07975837
107Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.07649344
108Degeneration of the lateral corticospinal tracts (HP:0002314)2.07649344
109Retinal dysplasia (HP:0007973)2.07634821
110Abnormality of salivation (HP:0100755)2.07128119
111Urinary urgency (HP:0000012)2.06919486
112Optic nerve hypoplasia (HP:0000609)2.05437873
113Hemiplegia (HP:0002301)2.04132293
114Aplasia involving bones of the upper limbs (HP:0009823)2.03560948
115Aplasia of the phalanges of the hand (HP:0009802)2.03560948
116Aplasia involving bones of the extremities (HP:0009825)2.03560948
117Acute necrotizing encephalopathy (HP:0006965)2.02006073
118Impaired smooth pursuit (HP:0007772)2.01748485
119Abnormality of the 4th metacarpal (HP:0010012)2.00567932
120Psychosis (HP:0000709)2.00257367
121Specific learning disability (HP:0001328)1.99872041
122Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.99836249
123Short 4th metacarpal (HP:0010044)1.99836249
124Sleep apnea (HP:0010535)1.98613708
125Termporal pattern (HP:0011008)1.98563181
126Insidious onset (HP:0003587)1.98563181
127Hypoplastic left heart (HP:0004383)1.98525447
128Left ventricular hypertrophy (HP:0001712)1.97527063
129Widely spaced teeth (HP:0000687)1.96111863
130Decreased testicular size (HP:0008734)1.96013535
131Pheochromocytoma (HP:0002666)1.95911384
132Abnormal hair whorl (HP:0010721)1.95623967
133Abnormal rod and cone electroretinograms (HP:0008323)1.94555972
134Genetic anticipation (HP:0003743)1.93843731
135Esotropia (HP:0000565)1.93263736
136Nephrogenic diabetes insipidus (HP:0009806)1.93018242
137Incomplete penetrance (HP:0003829)1.92344052
138Sclerocornea (HP:0000647)1.91594381
139Aplasia/Hypoplasia of the tongue (HP:0010295)1.91075088
140Pulmonary artery stenosis (HP:0004415)1.90774451
141Megalencephaly (HP:0001355)1.90381938
142Impaired vibratory sensation (HP:0002495)1.90021149
143Dynein arm defect of respiratory motile cilia (HP:0012255)1.88934877
144Absent/shortened dynein arms (HP:0200106)1.88934877
145Short nail (HP:0001799)1.88914295
146Anophthalmia (HP:0000528)1.88455323
147Abnormality of the lower motor neuron (HP:0002366)1.87549978
148Status epilepticus (HP:0002133)1.87369536
149Aplasia/Hypoplasia of the sternum (HP:0006714)1.87183867
150Lower limb muscle weakness (HP:0007340)1.86841295
151Genital tract atresia (HP:0001827)1.86783103
152Trigonocephaly (HP:0000243)1.86219946
153Hydroureter (HP:0000072)1.85629824
154Humeroradial synostosis (HP:0003041)1.85559470
155Synostosis involving the elbow (HP:0003938)1.85559470
156Progressive macrocephaly (HP:0004481)1.84463779
157Poor head control (HP:0002421)1.84282613
158Renal dysplasia (HP:0000110)1.83955040
159Pachygyria (HP:0001302)1.83591709
160Cystic liver disease (HP:0006706)1.82901668
161High anterior hairline (HP:0009890)1.82553604
162Stenosis of the external auditory canal (HP:0000402)1.82244675
163Craniofacial dystonia (HP:0012179)1.82080866
164Meningocele (HP:0002435)1.82054743
165Vaginal atresia (HP:0000148)1.82006207
166Obstructive sleep apnea (HP:0002870)1.82003490
167Cutaneous syndactyly (HP:0012725)1.81366889
168Aplasia/Hypoplasia of the lens (HP:0008063)1.80809525
169Hypoplastic scapulae (HP:0000882)1.80344139
170Aplasia/Hypoplasia of the scapulae (HP:0006713)1.80344139
171Hepatoblastoma (HP:0002884)1.80244195
172Intention tremor (HP:0002080)1.79195100
173Abnormal ciliary motility (HP:0012262)1.77785411
174Type II lissencephaly (HP:0007260)1.77410564
175Vertebral arch anomaly (HP:0008438)1.77313374
176Abnormality of the ischium (HP:0003174)1.76066821
177Preaxial hand polydactyly (HP:0001177)1.75862866
178Abnormality of ocular smooth pursuit (HP:0000617)1.75394809
179Growth hormone deficiency (HP:0000824)1.73837338
180Abnormal mitochondria in muscle tissue (HP:0008316)1.73821109
181Gastrointestinal atresia (HP:0002589)1.73541209
182Abnormality of the septum pellucidum (HP:0007375)1.69275091
183Bronchomalacia (HP:0002780)1.69011699
184Pancreatic cysts (HP:0001737)1.68822544

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.16136184
2NTRK34.81654333
3EPHB24.08761543
4MAP3K93.33360420
5MAP3K123.00398198
6MARK12.80833554
7CASK2.75473592
8RIPK42.72434151
9MAP3K42.63379070
10MAP2K72.61442965
11MINK12.45198416
12PLK42.32960316
13LRRK22.20007902
14EPHA32.17230878
15LIMK12.13128713
16CDK82.03385288
17NTRK22.02783574
18DYRK22.00127680
19PNCK1.98666021
20IRAK41.96392652
21ARAF1.88962051
22TNIK1.84870173
23MAP2K41.80510415
24DAPK21.76518422
25PLK21.65919601
26PAK61.63211903
27KSR21.63092372
28MAP4K21.62561560
29KSR11.60397027
30DAPK11.57910010
31MAP3K131.56302870
32EPHB11.50843667
33NTRK11.49362164
34BMPR21.49259075
35CDK51.44126571
36MAPK131.40962951
37GRK51.39636187
38NEK91.32635844
39PRKCG1.32614574
40SIK21.28070805
41CAMK2B1.27110269
42CDK191.26730634
43PRPF4B1.23964541
44FES1.23894182
45MAPK151.23865798
46CAMK2A1.22909760
47BMPR1B1.22555964
48CAMKK11.11946931
49FGFR21.07257932
50OXSR11.04175297
51DYRK31.03986307
52UHMK11.01866513
53NME11.01606455
54GRK70.98550622
55TESK10.98217332
56CSNK1G30.96263489
57PRKD30.94180410
58PTK2B0.93994571
59LMTK20.92312183
60SIK30.90780579
61BCR0.90555040
62STK390.88608003
63SGK4940.87572767
64SGK2230.87572767
65ERBB30.86007993
66CDK180.85784331
67CSNK1G10.84398752
68CAMK10.84240800
69CSNK1A1L0.84042777
70CDK140.83180692
71BRAF0.82155025
72CAMKK20.80710234
73CDK150.80669611
74DYRK1B0.80351966
75STK160.80132340
76STK380.79464318
77RAF10.77557669
78PAK20.76493635
79MAP3K20.75809693
80PINK10.75806304
81WEE10.75152607
82CAMK2D0.73770017
83CAMK1D0.72833893
84AKT30.71315779
85AKT20.70105990
86CDK11A0.69882765
87ADRBK20.68788687
88PRKCE0.67392591
89DYRK1A0.67387562
90LATS20.67048020
91BCKDK0.66798373
92SGK10.66773098
93SGK20.66318203
94MAP3K110.66141681
95CSNK1G20.65590585
96PAK30.63116338
97DDR20.62908512
98TNK20.61379032
99FGR0.61272654
100NEK60.60877161
101PTK60.58542602
102ROCK10.57793078
103STK110.57566129
104CAMK2G0.57067193
105TYRO30.56483665
106WNK30.55880905
107MUSK0.54898591
108PIM20.54130165
109MARK20.53342992
110PRKCH0.51503936
111CSNK1D0.48775047
112MAPKAPK50.47285809
113MAP3K10.46776296
114PHKG20.46681500
115PHKG10.46681500
116CAMK1G0.46152021
117PKN10.45626914
118RPS6KA40.44626638
119TSSK60.44523105
120NEK10.44315506
121PRKCZ0.44058468
122PKN20.43322350
123PDPK10.42946699
124WNK40.41725407
125PDK10.41530876
126GRK10.40739642
127ERBB20.39735003
128ROCK20.39389191
129INSRR0.38629385
130FYN0.38345743
131SGK30.36925987
132FER0.36781259
133RPS6KA30.35982693
134MOS0.35140616
135WNK10.35072123
136MAPK120.34718955
137ADRBK10.34440261
138CCNB10.34316499
139MAPK100.34217653
140TESK20.33877655
141PRKACA0.33799223
142IRAK20.32877528
143PRKCB0.32279402
144TGFBR10.31127159
145MAP2K10.31016671
146TIE10.27793266
147LATS10.27646592
148MAPK70.27132558
149CDK30.26025684

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.46871516
2Steroid biosynthesis_Homo sapiens_hsa001003.67075630
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.40035264
4Synaptic vesicle cycle_Homo sapiens_hsa047213.13117961
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.96490742
6Long-term potentiation_Homo sapiens_hsa047202.93977527
7Circadian entrainment_Homo sapiens_hsa047132.81862037
8GABAergic synapse_Homo sapiens_hsa047272.77989307
9Glutamatergic synapse_Homo sapiens_hsa047242.75057495
10Olfactory transduction_Homo sapiens_hsa047402.72959315
11Amphetamine addiction_Homo sapiens_hsa050312.70649773
12Morphine addiction_Homo sapiens_hsa050322.69046731
13Basal cell carcinoma_Homo sapiens_hsa052172.26531392
14Salivary secretion_Homo sapiens_hsa049702.26477839
15Dopaminergic synapse_Homo sapiens_hsa047282.25943598
16Taste transduction_Homo sapiens_hsa047422.07305542
17Serotonergic synapse_Homo sapiens_hsa047262.06713313
18Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.98248280
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.96425315
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.96055824
21Collecting duct acid secretion_Homo sapiens_hsa049661.94576660
22Long-term depression_Homo sapiens_hsa047301.90862227
23Cholinergic synapse_Homo sapiens_hsa047251.90051231
24Insulin secretion_Homo sapiens_hsa049111.87769098
25Ribosome_Homo sapiens_hsa030101.85660259
26Renin secretion_Homo sapiens_hsa049241.82140119
27Gastric acid secretion_Homo sapiens_hsa049711.79182445
28Calcium signaling pathway_Homo sapiens_hsa040201.77359808
29Cocaine addiction_Homo sapiens_hsa050301.77086049
30Hippo signaling pathway_Homo sapiens_hsa043901.76232151
31Sulfur relay system_Homo sapiens_hsa041221.74438421
32Aldosterone synthesis and secretion_Homo sapiens_hsa049251.65817202
33Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.65240751
34Oxytocin signaling pathway_Homo sapiens_hsa049211.61312526
35Oxidative phosphorylation_Homo sapiens_hsa001901.55482970
36Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.55032539
37Butanoate metabolism_Homo sapiens_hsa006501.54466357
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.52593212
39Mismatch repair_Homo sapiens_hsa034301.48880378
40Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.43299257
41GnRH signaling pathway_Homo sapiens_hsa049121.38527092
42Alzheimers disease_Homo sapiens_hsa050101.35940088
43Cardiac muscle contraction_Homo sapiens_hsa042601.33862507
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.33726616
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.31724667
46Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.28476077
47Gap junction_Homo sapiens_hsa045401.28014770
48cAMP signaling pathway_Homo sapiens_hsa040241.24004586
49Axon guidance_Homo sapiens_hsa043601.23535209
50Notch signaling pathway_Homo sapiens_hsa043301.22163065
51Parkinsons disease_Homo sapiens_hsa050121.21567968
52Vibrio cholerae infection_Homo sapiens_hsa051101.18844643
53Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.13379251
54Peroxisome_Homo sapiens_hsa041461.10448725
55Phototransduction_Homo sapiens_hsa047441.09971902
56Melanogenesis_Homo sapiens_hsa049161.08958844
57alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.06343308
58Nitrogen metabolism_Homo sapiens_hsa009101.05652538
59Primary bile acid biosynthesis_Homo sapiens_hsa001201.04333606
60Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03871591
61beta-Alanine metabolism_Homo sapiens_hsa004101.03419159
62RNA polymerase_Homo sapiens_hsa030201.03233091
63Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.02679214
64Phosphatidylinositol signaling system_Homo sapiens_hsa040701.02599588
65Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.01754857
66Protein export_Homo sapiens_hsa030600.98539756
67Vascular smooth muscle contraction_Homo sapiens_hsa042700.97191030
68Glioma_Homo sapiens_hsa052140.97068753
69Propanoate metabolism_Homo sapiens_hsa006400.96958359
70Estrogen signaling pathway_Homo sapiens_hsa049150.96075028
71Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.94171375
72cGMP-PKG signaling pathway_Homo sapiens_hsa040220.93803980
73Huntingtons disease_Homo sapiens_hsa050160.91557912
74ErbB signaling pathway_Homo sapiens_hsa040120.89980408
75Cyanoamino acid metabolism_Homo sapiens_hsa004600.89491158
76Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.89069647
77Fatty acid metabolism_Homo sapiens_hsa012120.82118355
78Nucleotide excision repair_Homo sapiens_hsa034200.80743539
79Oocyte meiosis_Homo sapiens_hsa041140.80471017
80Type II diabetes mellitus_Homo sapiens_hsa049300.79313158
81Tight junction_Homo sapiens_hsa045300.78768873
82Pancreatic secretion_Homo sapiens_hsa049720.78171127
83Linoleic acid metabolism_Homo sapiens_hsa005910.76182587
84African trypanosomiasis_Homo sapiens_hsa051430.74199914
85Folate biosynthesis_Homo sapiens_hsa007900.69415969
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.67969636
87Dorso-ventral axis formation_Homo sapiens_hsa043200.66668979
88Thyroid hormone synthesis_Homo sapiens_hsa049180.66049656
89Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.65801116
90RNA degradation_Homo sapiens_hsa030180.65408754
91Choline metabolism in cancer_Homo sapiens_hsa052310.64778805
92Arginine and proline metabolism_Homo sapiens_hsa003300.62275238
93Ras signaling pathway_Homo sapiens_hsa040140.61978778
94MAPK signaling pathway_Homo sapiens_hsa040100.61811404
95Fatty acid degradation_Homo sapiens_hsa000710.61618807
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.61156906
97Type I diabetes mellitus_Homo sapiens_hsa049400.60081975
98Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.58791943
99Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57041525
100Alcoholism_Homo sapiens_hsa050340.54792757
101Fat digestion and absorption_Homo sapiens_hsa049750.53497654
102Glycerolipid metabolism_Homo sapiens_hsa005610.53484521
103Rheumatoid arthritis_Homo sapiens_hsa053230.53243678
104Dilated cardiomyopathy_Homo sapiens_hsa054140.53068523
105Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.52573941
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.52393249
107PPAR signaling pathway_Homo sapiens_hsa033200.52295631
108Protein digestion and absorption_Homo sapiens_hsa049740.50281178
109Caffeine metabolism_Homo sapiens_hsa002320.50240771
110Prion diseases_Homo sapiens_hsa050200.49744836
111TGF-beta signaling pathway_Homo sapiens_hsa043500.49647250
112Sphingolipid signaling pathway_Homo sapiens_hsa040710.49363917
113SNARE interactions in vesicular transport_Homo sapiens_hsa041300.48317790
114Wnt signaling pathway_Homo sapiens_hsa043100.47273995
115VEGF signaling pathway_Homo sapiens_hsa043700.47231525
116Rap1 signaling pathway_Homo sapiens_hsa040150.47226973
117ECM-receptor interaction_Homo sapiens_hsa045120.44897107
118Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.44856229
119Histidine metabolism_Homo sapiens_hsa003400.41579583
120Glucagon signaling pathway_Homo sapiens_hsa049220.41462540
121Lysine degradation_Homo sapiens_hsa003100.37661094
122Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37241283
123Metabolic pathways_Homo sapiens_hsa011000.37049809
124Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36690904
125ABC transporters_Homo sapiens_hsa020100.35604556
126Pyruvate metabolism_Homo sapiens_hsa006200.35493239
127Inositol phosphate metabolism_Homo sapiens_hsa005620.34608460
128DNA replication_Homo sapiens_hsa030300.34430707
129Ovarian steroidogenesis_Homo sapiens_hsa049130.33126228
130Tryptophan metabolism_Homo sapiens_hsa003800.32395709
131Neurotrophin signaling pathway_Homo sapiens_hsa047220.32099099
132Bile secretion_Homo sapiens_hsa049760.30633759
133Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30618531
134Arachidonic acid metabolism_Homo sapiens_hsa005900.30579930
135Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.30209237
136Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30199244
137Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.29762514
138Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28993643
139Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28243453
140Melanoma_Homo sapiens_hsa052180.27885937
141Chemokine signaling pathway_Homo sapiens_hsa040620.26061695
142Circadian rhythm_Homo sapiens_hsa047100.26010513
143Renal cell carcinoma_Homo sapiens_hsa052110.24830854
144Carbohydrate digestion and absorption_Homo sapiens_hsa049730.24274418
145Thyroid hormone signaling pathway_Homo sapiens_hsa049190.24251825
146Endocytosis_Homo sapiens_hsa041440.24140643
147Phagosome_Homo sapiens_hsa041450.21895715
148Non-small cell lung cancer_Homo sapiens_hsa052230.21605995
149Ether lipid metabolism_Homo sapiens_hsa005650.20995228
150Mineral absorption_Homo sapiens_hsa049780.20291725
151Hedgehog signaling pathway_Homo sapiens_hsa043400.19035638
152Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.18815324
153Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.17485889

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »