LYPD8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maintenance of gastrointestinal epithelium (GO:0030277)9.00775744
2positive regulation of respiratory burst (GO:0060267)8.11221362
3bundle of His cell to Purkinje myocyte communication (GO:0086069)7.96490159
4UDP-N-acetylglucosamine metabolic process (GO:0006047)7.57916847
5hemidesmosome assembly (GO:0031581)7.16553077
6epithelial structure maintenance (GO:0010669)6.88960445
7intestinal epithelial cell development (GO:0060576)6.53233121
8cellular glucuronidation (GO:0052695)6.17985623
9uronic acid metabolic process (GO:0006063)5.92265529
10glucuronate metabolic process (GO:0019585)5.92265529
11glomerular filtration (GO:0003094)5.88674919
12O-glycan processing (GO:0016266)5.88421982
13renal system process involved in regulation of blood volume (GO:0001977)5.38184786
14renal filtration (GO:0097205)5.36098237
15actin filament depolymerization (GO:0030042)5.34521594
16L-fucose catabolic process (GO:0042355)5.34461066
17fucose catabolic process (GO:0019317)5.34461066
18L-fucose metabolic process (GO:0042354)5.34461066
19positive regulation of fatty acid beta-oxidation (GO:0032000)5.13124453
20hepatocyte apoptotic process (GO:0097284)5.10358812
21intestinal absorption (GO:0050892)5.09686092
22cGMP-mediated signaling (GO:0019934)5.08294654
23ethanol oxidation (GO:0006069)4.96286497
24glucocorticoid biosynthetic process (GO:0006704)4.82484380
25receptor guanylyl cyclase signaling pathway (GO:0007168)4.80459894
26bile acid and bile salt transport (GO:0015721)4.68576378
27prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060524.59700512
28regulation of respiratory burst (GO:0060263)4.59134300
29purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.58985925
303-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.58985925
31negative regulation of myotube differentiation (GO:0010832)4.54361917
32regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.48660587
33regulation of systemic arterial blood pressure by hormone (GO:0001990)4.47277857
34regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)4.47277857
35endocrine process (GO:0050886)4.47277857
36regulation of vitamin metabolic process (GO:0030656)4.38631580
37sulfate transmembrane transport (GO:1902358)4.38574119
38regulation of viral release from host cell (GO:1902186)4.38018763
39regulation of pseudopodium assembly (GO:0031272)4.37887709
40desmosome organization (GO:0002934)4.30482751
41sulfation (GO:0051923)4.28566055
42positive regulation of guanylate cyclase activity (GO:0031284)4.23081622
43vitamin transmembrane transport (GO:0035461)4.15608963
44regulation of intracellular pH (GO:0051453)4.15447601
45digestive system process (GO:0022600)4.13928722
46flavonoid metabolic process (GO:0009812)4.13460133
47thyroid hormone metabolic process (GO:0042403)4.10601515
48cellular response to pH (GO:0071467)4.09613310
49regulation of T cell tolerance induction (GO:0002664)4.09305198
50nucleotide-sugar biosynthetic process (GO:0009226)4.07259603
51ventricular cardiac muscle cell action potential (GO:0086005)4.05814703
52protein autoprocessing (GO:0016540)4.05446353
53regulation of RIG-I signaling pathway (GO:0039535)4.03480168
54antimicrobial humoral response (GO:0019730)3.98749411
55calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.98432551
56antibacterial humoral response (GO:0019731)3.98230991
57pyrimidine-containing compound transmembrane transport (GO:0072531)3.96869821
58positive regulation of synaptic transmission, GABAergic (GO:0032230)3.96294316
59positive regulation of fatty acid oxidation (GO:0046321)3.95440712
60regulation of cGMP biosynthetic process (GO:0030826)3.95238589
61ethanol metabolic process (GO:0006067)3.89673811
62regulation of cellular extravasation (GO:0002691)3.89498583
63labyrinthine layer development (GO:0060711)3.88892499
64one-carbon metabolic process (GO:0006730)3.88373831
65regulation of systemic arterial blood pressure (GO:0003073)3.82876578
66regulation of cellular pH (GO:0030641)3.80533006
67regulation of cell-cell adhesion mediated by cadherin (GO:2000047)3.79699829
68renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.76852714
69branching involved in prostate gland morphogenesis (GO:0060442)3.76542112
70sulfur amino acid catabolic process (GO:0000098)3.75337615
71production of molecular mediator involved in inflammatory response (GO:0002532)3.72794589
72regulation of hydrogen peroxide metabolic process (GO:0010310)3.70673911
73regulation of cholesterol homeostasis (GO:2000188)3.70102985
74lipopolysaccharide biosynthetic process (GO:0009103)3.68374154
75protein O-linked glycosylation (GO:0006493)3.66963224
76fucose metabolic process (GO:0006004)3.66722841
77positive regulation of actin filament depolymerization (GO:0030836)3.65817653
78transcytosis (GO:0045056)3.64938054
79nucleotide-sugar metabolic process (GO:0009225)3.60104503
80galactose catabolic process (GO:0019388)3.56769396
81negative regulation of protein tyrosine kinase activity (GO:0061099)3.53282381
82sulfate transport (GO:0008272)3.50585827
83regulation of chemokine secretion (GO:0090196)3.50278142
84lung secretory cell differentiation (GO:0061140)3.49065101
85response to acidic pH (GO:0010447)3.47371667
86cell differentiation involved in embryonic placenta development (GO:0060706)3.46127575
87fucosylation (GO:0036065)3.44871576
88angiotensin maturation (GO:0002003)3.43940501
89cell communication involved in cardiac conduction (GO:0086065)3.43801014
90positive regulation of systemic arterial blood pressure (GO:0003084)3.41958038
91NADH metabolic process (GO:0006734)3.39792147
92regulation of viral entry into host cell (GO:0046596)3.36768145
93regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)3.34282993
94regulation of pH (GO:0006885)3.33161079
95thrombin receptor signaling pathway (GO:0070493)3.32721913
96positive regulation of tolerance induction (GO:0002645)3.31862610
97eosinophil chemotaxis (GO:0048245)3.31080841
98positive regulation of glycoprotein biosynthetic process (GO:0010560)3.29953737
99fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.28410526
100regulation of fatty acid beta-oxidation (GO:0031998)3.26323405
101drug transmembrane transport (GO:0006855)3.25851516
102striated muscle atrophy (GO:0014891)3.25776614
103intestinal cholesterol absorption (GO:0030299)3.25629299
104sodium ion homeostasis (GO:0055078)3.25074912
105epithelial cell-cell adhesion (GO:0090136)3.24403319
106epoxygenase P450 pathway (GO:0019373)3.22704019
107regulation of cGMP metabolic process (GO:0030823)3.21321186
108regulation of heart rate by cardiac conduction (GO:0086091)3.19561105
109vitamin A metabolic process (GO:0006776)3.19426509
110regulation of guanylate cyclase activity (GO:0031282)3.18417412
111phosphatidylserine acyl-chain remodeling (GO:0036150)3.17580183
112cardiac conduction (GO:0061337)3.10329172
113GDP-mannose metabolic process (GO:0019673)3.08692609
114diol metabolic process (GO:0034311)3.08311101
115sulfur compound transport (GO:0072348)3.08206012
116positive regulation of glycoprotein metabolic process (GO:1903020)3.08059819
117neurotransmitter biosynthetic process (GO:0042136)3.07963111
118lipopolysaccharide metabolic process (GO:0008653)3.07533586
119monovalent inorganic cation homeostasis (GO:0055067)3.07409480
120excretion (GO:0007588)3.07163292
121hydrogen peroxide catabolic process (GO:0042744)3.05783116
122regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.03039137
123drug transport (GO:0015893)3.01497872
124auditory receptor cell differentiation (GO:0042491)3.01072964
125cellular monovalent inorganic cation homeostasis (GO:0030004)3.00140718
126thyroid hormone generation (GO:0006590)2.99213551
127glycosylceramide metabolic process (GO:0006677)2.99204802
128receptor recycling (GO:0001881)2.97987201
129diterpenoid biosynthetic process (GO:0016102)2.97971662
130phospholipid translocation (GO:0045332)2.97942823
131lipid translocation (GO:0034204)2.97942823
132cellular ketone body metabolic process (GO:0046950)2.97190821
133negative regulation of leukocyte chemotaxis (GO:0002689)2.95953991
134cellular response to hepatocyte growth factor stimulus (GO:0035729)2.95857855
135response to hepatocyte growth factor (GO:0035728)2.95857855
136eosinophil migration (GO:0072677)2.93802056
137activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.93174168
138positive regulation of pseudopodium assembly (GO:0031274)2.92569274
139antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.92401262
140negative regulation of keratinocyte proliferation (GO:0010839)2.90976477
141sperm capacitation (GO:0048240)2.90843269
142fat-soluble vitamin biosynthetic process (GO:0042362)2.90809898
143oligosaccharide biosynthetic process (GO:0009312)2.90338006
144membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.90116477
145positive regulation of epidermal cell differentiation (GO:0045606)2.88944303
146positive regulation of lipid catabolic process (GO:0050996)2.88751173
147tight junction assembly (GO:0070830)2.86735247
148phosphatidylcholine biosynthetic process (GO:0006656)2.86716292
149positive regulation of Cdc42 GTPase activity (GO:0043089)2.86646695
150bicarbonate transport (GO:0015701)2.85532608
151urea cycle (GO:0000050)2.85326592
152regulation of protein glycosylation (GO:0060049)2.84922887
153phosphatidylserine metabolic process (GO:0006658)2.84705579
154nucleoside diphosphate biosynthetic process (GO:0009133)2.84548003
155drug catabolic process (GO:0042737)2.83862922
156negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.81792515
157skeletal muscle adaptation (GO:0043501)2.81438624
158glandular epithelial cell differentiation (GO:0002067)2.81027140
159hexose catabolic process (GO:0019320)2.80494495

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human8.49382795
2CDX2_20551321_ChIP-Seq_CACO-2_Human5.27975082
3SOX2_27498859_Chip-Seq_STOMACH_Mouse3.79120445
4SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.19515620
5SOX2_20726797_ChIP-Seq_SW620_Human3.13660986
6TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.09056820
7GATA4_25053715_ChIP-Seq_YYC3_Human2.96871030
8CDX2_19796622_ChIP-Seq_MESCs_Mouse2.82938479
9GATA6_25053715_ChIP-Seq_YYC3_Human2.79641841
10ESR1_20079471_ChIP-ChIP_T-47D_Human2.49976617
11IRF8_22096565_ChIP-ChIP_GC-B_Human2.48715990
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.42309374
13CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.14087190
14KLF5_25053715_ChIP-Seq_YYC3_Human2.10315367
15STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.08419205
16ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse2.07835726
17SRY_22984422_ChIP-ChIP_TESTIS_Rat2.07452547
18ESR2_21235772_ChIP-Seq_MCF-7_Human2.02655440
19PPAR_26484153_Chip-Seq_NCI-H1993_Human1.98044904
20ESR1_21235772_ChIP-Seq_MCF-7_Human1.97617740
21RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.97336109
22FOXO3_23340844_ChIP-Seq_DLD1_Human1.93121566
23TRIM28_21343339_ChIP-Seq_HEK293_Human1.89447626
24PPARA_22158963_ChIP-Seq_LIVER_Mouse1.89080260
25RUNX1_27514584_Chip-Seq_MCF-7_Human1.89061082
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.88498090
27SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.85260536
28ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.83371394
29FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.81353026
30KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.80919367
31RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.75676677
32TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.71110803
33RACK7_27058665_Chip-Seq_MCF-7_Human1.70157022
34FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.66990378
35ZNF263_19887448_ChIP-Seq_K562_Human1.63423972
36ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.61003300
37EGR1_23403033_ChIP-Seq_LIVER_Mouse1.60834612
38NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.60479763
39VDR_22108803_ChIP-Seq_LS180_Human1.57392087
40PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.52987373
41CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.52936276
42EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.52371300
43KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.51776304
44RXR_22158963_ChIP-Seq_LIVER_Mouse1.50975794
45ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.50082391
46RARG_19884340_ChIP-ChIP_MEFs_Mouse1.49827490
47KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.49149065
48SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.49085292
49SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.49085292
50LXR_22158963_ChIP-Seq_LIVER_Mouse1.43459407
51MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.43214811
52TCF4_18268006_ChIP-ChIP_LS174T_Human1.40468814
53FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.38327851
54BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.35437317
55BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.35138498
56NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.34934060
57VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.34471242
58ATF3_27146783_Chip-Seq_COLON_Human1.34132891
59CEBPB_22108803_ChIP-Seq_LS180_Human1.31715054
60PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.29329309
61ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.28666445
62AR_21909140_ChIP-Seq_LNCAP_Human1.27759967
63HIF1A_21447827_ChIP-Seq_MCF-7_Human1.25714066
64ZNF217_24962896_ChIP-Seq_MCF-7_Human1.25683796
65JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.25334618
66DROSHA_22980978_ChIP-Seq_HELA_Human1.22043064
67BCAT_22108803_ChIP-Seq_LS180_Human1.21404286
68CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17694568
69TET1_21451524_ChIP-Seq_MESCs_Mouse1.11931753
70STAT1_20625510_ChIP-Seq_HELA_Human1.11566891
71SMAD_19615063_ChIP-ChIP_OVARY_Human1.10198214
72IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.09604143
73JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.07026886
74GATA1_19941826_ChIP-Seq_K562_Human1.06955996
75E2F1_20622854_ChIP-Seq_HELA_Human1.06839143
76P63_26484246_Chip-Seq_KERATINOCYTES_Human1.05486740
77AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.04758575
78GATA2_19941826_ChIP-Seq_K562_Human1.04266888
79GATA3_24758297_ChIP-Seq_MCF-7_Human1.03824727
80FOXA1_25552417_ChIP-Seq_VCAP_Human1.03565839
81FOXM1_26456572_ChIP-Seq_MCF-7_Human1.02576902
82POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.01794534
83SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00128104
84CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00027580
85CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.99862588
86BCL6_27268052_Chip-Seq_Bcells_Human0.99186216
87SA1_27219007_Chip-Seq_Bcells_Human0.98227859
88NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.97190257
89CREB1_26743006_Chip-Seq_LNCaP_Human0.97161064
90FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.96303206
91CLOCK_20551151_ChIP-Seq_293T_Human0.94212754
92SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.91930636
93THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.91698565
94RAD21_21589869_ChIP-Seq_MESCs_Mouse0.91633730
95TCF3_18692474_ChIP-Seq_MEFs_Mouse0.91518455
96CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.90590064
97FOXA2_19822575_ChIP-Seq_HepG2_Human0.90043165
98UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.89869281
99CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.89049926
100SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.88294497
101NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.87636579
102HNF4A_19822575_ChIP-Seq_HepG2_Human0.87545788
103BCOR_27268052_Chip-Seq_Bcells_Human0.86762867
104EGR1_19032775_ChIP-ChIP_M12_Human0.86622243
105GATA1_22383799_ChIP-Seq_G1ME_Mouse0.86158599
106GATA2_21666600_ChIP-Seq_HMVEC_Human0.85875922
107ELF5_23300383_ChIP-Seq_T47D_Human0.85163473
108GATA1_26923725_Chip-Seq_HPCs_Mouse0.84929428
109ETS1_21867929_ChIP-Seq_TH2_Mouse0.84219592
110LXR_22292898_ChIP-Seq_THP-1_Human0.83867521
111CDX2_22108803_ChIP-Seq_LS180_Human0.82909544
112CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.82228024
113TP63_22573176_ChIP-Seq_HFKS_Human0.82142017
114NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.81157183
115PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.80612897
116PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.80443554
117CTNNB1_20460455_ChIP-Seq_HCT116_Human0.78495152
118SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.78292511
119GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.77938835
120OCT4_18692474_ChIP-Seq_MEFs_Mouse0.77484399
121PHF8_20622854_ChIP-Seq_HELA_Human0.77001929
122EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.76349034
123PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.75399685
124NANOG_18692474_ChIP-Seq_MEFs_Mouse0.75170378
125TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.74831385
126CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.74683201
127KAP1_22055183_ChIP-Seq_ESCs_Mouse0.72946149
128SALL4_18804426_ChIP-ChIP_XEN_Mouse0.72943134
129GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.72863200
130TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.72646695
131P300_27058665_Chip-Seq_ZR-75-30cells_Human0.72590000
132ELK3_25401928_ChIP-Seq_HUVEC_Human0.71892125
133NANOG_20526341_ChIP-Seq_ESCs_Human0.71267526

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010234_abnormal_vibrissa_follicle7.94804220
2MP0004264_abnormal_extraembryonic_tissu4.76639304
3MP0003866_abnormal_defecation4.14292136
4MP0000462_abnormal_digestive_system3.97391789
5MP0001666_abnormal_nutrient_absorption3.31253603
6MP0000537_abnormal_urethra_morphology3.24423530
7MP0010155_abnormal_intestine_physiology2.97560541
8MP0002822_catalepsy2.87336406
9MP0001663_abnormal_digestive_system2.86404603
10MP0005381_digestive/alimentary_phenotyp2.80120570
11MP0001873_stomach_inflammation2.70996544
12MP0003283_abnormal_digestive_organ2.68026758
13MP0005360_urolithiasis2.61967241
14MP0000490_abnormal_crypts_of2.47731891
15MP0002138_abnormal_hepatobiliary_system2.46421180
16MP0005085_abnormal_gallbladder_physiolo2.42772620
17MP0000477_abnormal_intestine_morphology2.29768358
18MP0001664_abnormal_digestion2.28740478
19MP0003705_abnormal_hypodermis_morpholog2.28516276
20MP0010352_gastrointestinal_tract_polyps2.27244037
21MP0001849_ear_inflammation2.25482152
22MP0006054_spinal_hemorrhage2.25479762
23MP0005167_abnormal_blood-brain_barrier2.16054319
24MP0010678_abnormal_skin_adnexa2.05546987
25MP0005377_hearing/vestibular/ear_phenot1.91886441
26MP0003878_abnormal_ear_physiology1.91886441
27MP0003183_abnormal_peptide_metabolism1.90496684
28MP0008875_abnormal_xenobiotic_pharmacok1.89334699
29MP0003300_gastrointestinal_ulcer1.84254602
30MP0000538_abnormal_urinary_bladder1.77743975
31MP0001765_abnormal_ion_homeostasis1.70211231
32MP0002876_abnormal_thyroid_physiology1.67867201
33MP0002796_impaired_skin_barrier1.65417597
34MP0005409_darkened_coat_color1.54731411
35MP0002009_preneoplasia1.53791776
36MP0003453_abnormal_keratinocyte_physiol1.50973227
37MP0003724_increased_susceptibility_to1.50962138
38MP0008004_abnormal_stomach_pH1.50222537
39MP0005670_abnormal_white_adipose1.48514921
40MP0004947_skin_inflammation1.44073285
41MP0000678_abnormal_parathyroid_gland1.43062351
42MP0003315_abnormal_perineum_morphology1.42100204
43MP0003252_abnormal_bile_duct1.36706842
44MP0005365_abnormal_bile_salt1.34336837
45MP0003868_abnormal_feces_composition1.33714650
46MP0005451_abnormal_body_composition1.32447685
47MP0002139_abnormal_hepatobiliary_system1.31251805
48MP0005187_abnormal_penis_morphology1.30223864
49MP0002166_altered_tumor_susceptibility1.27925556
50MP0002060_abnormal_skin_morphology1.23600581
51MP0000230_abnormal_systemic_arterial1.23406452
52MP0009379_abnormal_foot_pigmentation1.22088963
53MP0003806_abnormal_nucleotide_metabolis1.21458426
54MP0005166_decreased_susceptibility_to1.21092408
55MP0001216_abnormal_epidermal_layer1.19466202
56MP0005310_abnormal_salivary_gland1.18581078
57MP0002234_abnormal_pharynx_morphology1.17743449
58MP0003879_abnormal_hair_cell1.15960318
59MP0000470_abnormal_stomach_morphology1.15060877
60MP0005501_abnormal_skin_physiology1.14927596
61MP0003303_peritoneal_inflammation1.14250466
62MP0003693_abnormal_embryo_hatching1.13658101
63MP0005636_abnormal_mineral_homeostasis1.13579022
64MP0002909_abnormal_adrenal_gland1.11567994
65MP0002098_abnormal_vibrissa_morphology1.11059085
66MP0008872_abnormal_physiological_respon1.10541519
67MP0001188_hyperpigmentation1.06128001
68MP0009053_abnormal_anal_canal1.06018822
69MP0009643_abnormal_urine_homeostasis1.05065685
70MP0004782_abnormal_surfactant_physiolog1.03577587
71MP0000467_abnormal_esophagus_morphology1.02964416
72MP0004043_abnormal_pH_regulation1.02663162
73MP0004019_abnormal_vitamin_homeostasis0.95959253
74MP0009840_abnormal_foam_cell0.93958212
75MP0010329_abnormal_lipoprotein_level0.93748870
76MP0004147_increased_porphyrin_level0.92839209
77MP0009384_cardiac_valve_regurgitation0.89939979
78MP0005257_abnormal_intraocular_pressure0.89781047
79MP0009785_altered_susceptibility_to0.87989070
80MP0002277_abnormal_respiratory_mucosa0.87628842
81MP0003566_abnormal_cell_adhesion0.86563380
82MP0006082_CNS_inflammation0.85840463
83MP0004484_altered_response_of0.85018405
84MP0010771_integument_phenotype0.83486783
85MP0003191_abnormal_cellular_cholesterol0.82628309
86MP0003045_fibrosis0.82193953
87MP0005367_renal/urinary_system_phenotyp0.82015011
88MP0000516_abnormal_urinary_system0.82015011
89MP0004858_abnormal_nervous_system0.81339325
90MP0003075_altered_response_to0.79741707
91MP0005058_abnormal_lysosome_morphology0.79135264
92MP0002118_abnormal_lipid_homeostasis0.77784472
93MP0000383_abnormal_hair_follicle0.74578625
94MP0000377_abnormal_hair_follicle0.74213095
95MP0005275_abnormal_skin_tensile0.73441466
96MP0000762_abnormal_tongue_morphology0.73209016
97MP0005666_abnormal_adipose_tissue0.72924457
98MP0000465_gastrointestinal_hemorrhage0.72448072
99MP0002136_abnormal_kidney_physiology0.72002288
100MP0005332_abnormal_amino_acid0.70014325
101MP0000604_amyloidosis0.68209808
102MP0005584_abnormal_enzyme/coenzyme_acti0.67726075
103MP0004272_abnormal_basement_membrane0.66917953
104MP0001764_abnormal_homeostasis0.66128267
105MP0002132_abnormal_respiratory_system0.63289473
106MP0001845_abnormal_inflammatory_respons0.63040118
107MP0003329_amyloid_beta_deposits0.62268804
108MP0005319_abnormal_enzyme/_coenzyme0.60833234
109MP0002896_abnormal_bone_mineralization0.60298645
110MP0005023_abnormal_wound_healing0.59356385
111MP0001727_abnormal_embryo_implantation0.59220759
112MP0000566_synostosis0.58404596
113MP0009333_abnormal_splenocyte_physiolog0.57174222
114MP0001485_abnormal_pinna_reflex0.57112050
115MP0008873_increased_physiological_sensi0.56715787
116MP0002971_abnormal_brown_adipose0.56587869
117MP0005025_abnormal_response_to0.56478413
118MP0004185_abnormal_adipocyte_glucose0.55363255
119MP0000609_abnormal_liver_physiology0.55041793
120MP0002006_tumorigenesis0.54764874
121MP0003941_abnormal_skin_development0.54346918
122MP0000613_abnormal_salivary_gland0.54111549
123MP0005248_abnormal_Harderian_gland0.53256984
124MP0005165_increased_susceptibility_to0.53192768
125MP0002148_abnormal_hypersensitivity_rea0.52848241
126MP0001756_abnormal_urination0.52633481
127MP0001501_abnormal_sleep_pattern0.51845264
128MP0001790_abnormal_immune_system0.51252601
129MP0005387_immune_system_phenotype0.51252601

Predicted human phenotypes

RankGene SetZ-score
1Right ventricular cardiomyopathy (HP:0011663)7.59651402
2Ileus (HP:0002595)6.62971841
3Onycholysis (HP:0001806)6.30125401
4Milia (HP:0001056)5.51657606
5Hyperactive renin-angiotensin system (HP:0000841)5.30174977
6Fragile nails (HP:0001808)5.27648349
7Atrophic scars (HP:0001075)5.07168742
8Abnormality of the 1st metacarpal (HP:0010009)4.80710624
9Flat acetabular roof (HP:0003180)4.60964431
10Hyponatremia (HP:0002902)4.58435553
11Pustule (HP:0200039)4.33933153
12Abdominal distention (HP:0003270)4.16190587
13Hypokalemia (HP:0002900)4.08663758
14Abnormal tarsal ossification (HP:0008369)4.08420548
15Abnormality of the distal phalanx of the thumb (HP:0009617)4.07348209
16Metabolic alkalosis (HP:0200114)3.98756685
17Ureteral stenosis (HP:0000071)3.88805153
18Abnormality of potassium homeostasis (HP:0011042)3.74497281
19Flat capital femoral epiphysis (HP:0003370)3.62443201
20Plantar hyperkeratosis (HP:0007556)3.59219773
21Ureteral obstruction (HP:0006000)3.58075553
22Micronodular cirrhosis (HP:0001413)3.56472843
23Abnormality of chloride homeostasis (HP:0011422)3.53811015
24Abnormality of sodium homeostasis (HP:0010931)3.44589770
25Pili torti (HP:0003777)3.42877605
26Abnormality of carpal bone ossification (HP:0006257)3.38873515
27Villous atrophy (HP:0011473)3.37699966
28Abnormality of small intestinal villus morphology (HP:0011472)3.37699966
29Hemorrhage of the eye (HP:0011885)3.36838386
30Short phalanx of the thumb (HP:0009660)3.35297741
31Woolly hair (HP:0002224)3.34198639
32Malnutrition (HP:0004395)3.27944514
33Symphalangism affecting the phalanges of the hand (HP:0009773)3.26946553
34Hyperkalemia (HP:0002153)3.25247669
35Palpitations (HP:0001962)3.25131547
36Abnormality of renin-angiotensin system (HP:0000847)3.16365699
37Biliary tract neoplasm (HP:0100574)3.12370278
38Visceral angiomatosis (HP:0100761)3.08672373
39Ventricular fibrillation (HP:0001663)3.08128322
40Mildly elevated creatine phosphokinase (HP:0008180)3.07436870
41Abnormal foot bone ossification (HP:0010675)3.03195492
42Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.99480646
43Short 1st metacarpal (HP:0010034)2.99480646
44Abnormality of the 2nd finger (HP:0004100)2.96450918
45Adrenal overactivity (HP:0002717)2.93466656
46Goiter (HP:0000853)2.90413163
47Dehydration (HP:0001944)2.87151217
48Decreased circulating renin level (HP:0003351)2.80853840
49Gastrointestinal dysmotility (HP:0002579)2.80055971
50Abnormality of the phalanges of the hallux (HP:0010057)2.78866546
51Hemangiomatosis (HP:0007461)2.76288924
52Conjugated hyperbilirubinemia (HP:0002908)2.75957550
53Hypoplasia of dental enamel (HP:0006297)2.69548051
54Breech presentation (HP:0001623)2.69425058
55Ventricular tachycardia (HP:0004756)2.68260639
56Flattened epiphyses (HP:0003071)2.63493524
57Esophageal atresia (HP:0002032)2.62687857
58Abnormal ossification of hand bones (HP:0005921)2.59294786
59Cupped ribs (HP:0000887)2.58856163
60Hoarse voice (HP:0001609)2.58482072
61Syncope (HP:0001279)2.58418435
62Fragile skin (HP:0001030)2.58313500
63Abnormal biliary tract morphology (HP:0012440)2.57853670
64Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.56748436
65Abnormal hand bone ossification (HP:0010660)2.56436213
66Abnormality of the vitamin B12 metabolism (HP:0004341)2.56427512
67Curly hair (HP:0002212)2.50831156
68Rectal prolapse (HP:0002035)2.44725013
69Short middle phalanx of finger (HP:0005819)2.42927821
70Abnormality of the gastric mucosa (HP:0004295)2.42296777
71Fat malabsorption (HP:0002630)2.40051458
72Intrahepatic cholestasis (HP:0001406)2.39245030
73Hyperaldosteronism (HP:0000859)2.38447386
74Congenital sensorineural hearing impairment (HP:0008527)2.37679021
75Short hallux (HP:0010109)2.36982151
76Abnormality of dicarboxylic acid metabolism (HP:0010995)2.36496965
77Dicarboxylic aciduria (HP:0003215)2.36496965
78Progressive sensorineural hearing impairment (HP:0000408)2.35133292
79Chronic diarrhea (HP:0002028)2.34249328
80Abnormality of vitamin B metabolism (HP:0004340)2.34083693
81Hyperparathyroidism (HP:0000843)2.31933792
82Large earlobe (HP:0009748)2.30988141
83Abnormality of the middle phalanges of the toes (HP:0010183)2.30501991
84Esophageal varix (HP:0002040)2.28195689
85Petechiae (HP:0000967)2.28131283
86Neonatal short-limb short stature (HP:0008921)2.27685619
87Hyperammonemia (HP:0001987)2.25497266
88Eczematoid dermatitis (HP:0000976)2.23590036
89Abnormal cartilage morphology (HP:0002763)2.23195585
90Nail dystrophy (HP:0008404)2.22879382
91Abnormality of glutamine family amino acid metabolism (HP:0010902)2.21242662
92Vertebral hypoplasia (HP:0008417)2.18409541
93Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.18409541
94Systemic lupus erythematosus (HP:0002725)2.16824962
95Neoplasm of the small intestine (HP:0100833)2.16444262
96Neoplasm of the rectum (HP:0100743)2.15805848
97Ventricular arrhythmia (HP:0004308)2.15709995
98Spinal cord compression (HP:0002176)2.15261651
99Aplasia/Hypoplasia of the hallux (HP:0008362)2.14088091
100Absent phalangeal crease (HP:0006109)2.12411154
101Vascular calcification (HP:0004934)2.10874570
102Uterine neoplasm (HP:0010784)2.09083209
103Irregular epiphyses (HP:0010582)2.08903999
104Septate vagina (HP:0001153)2.07972905
105Abnormality of the distal phalanges of the toes (HP:0010182)2.07197146
106Abnormality of the proximal phalanges of the hand (HP:0009834)2.05775770
107Vertebral clefting (HP:0008428)2.04824985
108Abnormal hair laboratory examination (HP:0003328)2.04533515
109Progressive hearing impairment (HP:0001730)2.02758894
110Hypotension (HP:0002615)2.00420405
111Abnormality of vitamin metabolism (HP:0100508)1.98078213
112Alkalosis (HP:0001948)1.96222985
113Amelogenesis imperfecta (HP:0000705)1.94446159
114Myopathic facies (HP:0002058)1.93560402
115Late onset (HP:0003584)1.93374278
116Microretrognathia (HP:0000308)1.90856312
117Renal tubular acidosis (HP:0001947)1.90597428
118Alopecia of scalp (HP:0002293)1.90131427
119Abnormality of monocarboxylic acid metabolism (HP:0010996)1.89679672
120Chronic bronchitis (HP:0004469)1.89203131
121Hydroxyprolinuria (HP:0003080)1.88756401
122Abnormality of proline metabolism (HP:0010907)1.88756401
123Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.88712825
124Cardiovascular calcification (HP:0011915)1.88538283
125Cerebral hemorrhage (HP:0001342)1.87576217
126Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.87116062
127Aplasia/hypoplasia of the femur (HP:0005613)1.86438891
128Focal segmental glomerulosclerosis (HP:0000097)1.83346796
129Thin bony cortex (HP:0002753)1.83294111
130Cerebral palsy (HP:0100021)1.81866042
131Abnormal vertebral ossification (HP:0100569)1.81186309
132Severe short stature (HP:0003510)1.79710719
133Symptomatic seizures (HP:0011145)1.74761792
134Renal salt wasting (HP:0000127)1.73988692
135Abnormality of magnesium homeostasis (HP:0004921)1.71845410
136Growth hormone excess (HP:0000845)1.67234460
137Segmental peripheral demyelination/remyelination (HP:0003481)1.64661192
138Protuberant abdomen (HP:0001538)1.64084383
139Cone-rod dystrophy (HP:0000548)1.63247977
140Hyperphosphatemia (HP:0002905)1.61943068
141Widely patent fontanelles and sutures (HP:0004492)1.60360902
142Ankle clonus (HP:0011448)1.58764262
143Bone pain (HP:0002653)1.58695529
144Bundle branch block (HP:0011710)1.56672234
145Confusion (HP:0001289)1.53797033

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R6.84938522
2ACVR1B5.78376726
3MST44.39161037
4FRK4.27410219
5PIK3CA4.08840504
6LMTK23.86326298
7MAP2K23.74027671
8NME12.93431340
9EPHA22.91307592
10RIPK12.81080879
11TESK12.78607588
12MET2.47715721
13PRKG22.44552089
14EPHB22.31394722
15MYLK2.03273754
16MAP3K22.00437013
17KSR21.92246744
18PTK61.92077036
19MAP2K11.67289397
20TAOK31.65532634
21MAP3K121.51960485
22LIMK11.45097517
23STK241.36670132
24TAOK11.30906104
25FER1.24160063
26PTK21.22216407
27PAK41.22054378
28GRK61.17572794
29MAP3K91.15803657
30MAP2K61.11803276
31PDK21.07944255
32CAMK2D1.06041188
33PKN21.04693262
34RIPK40.98727868
35PRKCI0.98247054
36MAP3K10.95186783
37MAP3K100.94320354
38ERN10.94097218
39EPHA40.92987575
40STK100.92593469
41DDR20.91355442
42EEF2K0.90982602
43ABL20.90830195
44EPHB10.89609866
45ERBB20.85543529
46MAP3K80.82132489
47MATK0.81427686
48DMPK0.75414884
49PRPF4B0.74297293
50MAP3K110.71798902
51MAP3K70.67573360
52ERBB40.66551614
53PAK30.63624905
54LRRK20.61875678
55CAMK2B0.61623792
56PRKAA20.60005115
57EPHA30.59853331
58NUAK10.59326809
59BMX0.58216491
60RPS6KB20.58134101
61MAP3K130.55753335
62CAMK2G0.54369678
63ICK0.54332946
64AURKB0.52581347
65MAPK110.52111820
66ARAF0.48163047
67CDK190.46946303
68TESK20.44662452
69MAP4K10.43816278
70PAK10.43808753
71FGFR30.42721833
72SRC0.41248473
73TNIK0.40622115
74STK390.38098499
75LATS10.36471758
76SMG10.34454094
77YES10.34134745
78TTK0.33925448
79TBK10.33416110
80MAP3K30.33220725
81RET0.33171806
82CSK0.33123777
83ZAP700.32510665
84PDPK10.32504946
85TRIB30.32175775
86PRKCA0.31399300
87FGFR40.30973637
88NEK10.30451413
89MELK0.30080601
90MAP3K140.29803444
91NME20.29223341
92PRKAA10.28718154
93BMPR20.28671125
94BCR0.28178245
95KSR10.28127860
96SIK30.27945747
97TRPM70.27943666
98ROCK10.27066476
99WNK40.26991959
100MAPKAPK30.26677111
101JAK20.25895263
102CDC42BPA0.24496662
103PRKCQ0.24381581
104TYK20.23823428
105PIK3CG0.23344855
106PIM20.22837571
107FYN0.22067800
108OXSR10.21888299
109PDK10.21748559
110DAPK30.21736767
111PAK20.21701052
112IRAK10.21268290
113CASK0.19750558
114SCYL20.19579013
115ALK0.18629825
116LYN0.17734725
117CSNK1A10.16940157
118PRKCZ0.16754384
119PDGFRA0.16719871
120RPS6KA20.16320074
121MAPKAPK20.15543978
122GRK10.15259084
123PRKCD0.14766857
124ROCK20.14714310
125NLK0.14624096
126PRKACG0.14115908
127CDK60.13913166
128PBK0.13769893
129FGFR10.13575892
130DAPK10.12507200
131MINK10.09162721
132IGF1R0.08996957
133PRKCB0.08264874
134NEK60.07242661
135PINK10.06322270
136MAP3K50.06150726

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009205.61379607
2Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006014.89576081
3Mineral absorption_Homo sapiens_hsa049783.66583972
4Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.85565742
5Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.76885941
6Fat digestion and absorption_Homo sapiens_hsa049752.63922611
7Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.61840531
8Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.55276982
9Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005202.40612441
10Bile secretion_Homo sapiens_hsa049762.08556038
11Fructose and mannose metabolism_Homo sapiens_hsa000511.82078197
12Drug metabolism - other enzymes_Homo sapiens_hsa009831.79326676
13Histidine metabolism_Homo sapiens_hsa003401.72839052
14Retinol metabolism_Homo sapiens_hsa008301.68920754
15Caffeine metabolism_Homo sapiens_hsa002321.68670700
16Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.57861028
17Galactose metabolism_Homo sapiens_hsa000521.57168695
18Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.56895227
19Thyroid hormone synthesis_Homo sapiens_hsa049181.56074324
20Maturity onset diabetes of the young_Homo sapiens_hsa049501.51731843
21Tight junction_Homo sapiens_hsa045301.49957547
22Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.48399885
23Pancreatic secretion_Homo sapiens_hsa049721.41307533
24Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.40908071
25Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.39610029
26Tryptophan metabolism_Homo sapiens_hsa003801.35433972
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.35028704
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.32143932
29Salivary secretion_Homo sapiens_hsa049701.25250507
30Glutathione metabolism_Homo sapiens_hsa004801.23371250
31Salmonella infection_Homo sapiens_hsa051321.18982822
32Other glycan degradation_Homo sapiens_hsa005111.17128748
33Renin-angiotensin system_Homo sapiens_hsa046141.16098615
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.11654349
35Linoleic acid metabolism_Homo sapiens_hsa005911.07380413
36Thyroid cancer_Homo sapiens_hsa052161.03597882
37Pentose and glucuronate interconversions_Homo sapiens_hsa000401.03590370
38African trypanosomiasis_Homo sapiens_hsa051431.01476281
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.95075510
40Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.91976325
41Adherens junction_Homo sapiens_hsa045200.91816995
42Butanoate metabolism_Homo sapiens_hsa006500.91675459
43Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.90633811
44Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.89958904
45Protein digestion and absorption_Homo sapiens_hsa049740.87971273
46Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86931615
47Glycerolipid metabolism_Homo sapiens_hsa005610.83785458
48Starch and sucrose metabolism_Homo sapiens_hsa005000.82136951
49Hepatitis C_Homo sapiens_hsa051600.82062524
50Gastric acid secretion_Homo sapiens_hsa049710.81871663
51Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.81273215
52Bladder cancer_Homo sapiens_hsa052190.80772660
53Fatty acid degradation_Homo sapiens_hsa000710.79231537
54Carbohydrate digestion and absorption_Homo sapiens_hsa049730.77721034
55Vitamin digestion and absorption_Homo sapiens_hsa049770.77680767
56Folate biosynthesis_Homo sapiens_hsa007900.75460244
57Toxoplasmosis_Homo sapiens_hsa051450.74453355
58Fatty acid metabolism_Homo sapiens_hsa012120.74139076
59Pertussis_Homo sapiens_hsa051330.70822301
60Amoebiasis_Homo sapiens_hsa051460.70326334
61Arginine biosynthesis_Homo sapiens_hsa002200.68948986
62Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.68263207
63Arachidonic acid metabolism_Homo sapiens_hsa005900.67910929
64Pentose phosphate pathway_Homo sapiens_hsa000300.66735612
65Asthma_Homo sapiens_hsa053100.66376799
66Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.65903625
67Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.64851099
68Propanoate metabolism_Homo sapiens_hsa006400.62867314
69Oxidative phosphorylation_Homo sapiens_hsa001900.61776181
70PPAR signaling pathway_Homo sapiens_hsa033200.61425726
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60081691
72Arginine and proline metabolism_Homo sapiens_hsa003300.58700812
73Nitrogen metabolism_Homo sapiens_hsa009100.57018958
74Chemical carcinogenesis_Homo sapiens_hsa052040.55292628
75Renin secretion_Homo sapiens_hsa049240.53523964
76Alzheimers disease_Homo sapiens_hsa050100.51366134
77N-Glycan biosynthesis_Homo sapiens_hsa005100.51314389
78Sphingolipid metabolism_Homo sapiens_hsa006000.51272202
79Glycerophospholipid metabolism_Homo sapiens_hsa005640.50406181
80ECM-receptor interaction_Homo sapiens_hsa045120.50106852
81Tyrosine metabolism_Homo sapiens_hsa003500.49382971
82Ether lipid metabolism_Homo sapiens_hsa005650.49324803
83Peroxisome_Homo sapiens_hsa041460.48757182
84Carbon metabolism_Homo sapiens_hsa012000.47478139
85Sulfur relay system_Homo sapiens_hsa041220.46634091
86Intestinal immune network for IgA production_Homo sapiens_hsa046720.45781008
87Allograft rejection_Homo sapiens_hsa053300.44764788
88Influenza A_Homo sapiens_hsa051640.44741037
89Small cell lung cancer_Homo sapiens_hsa052220.43815746
90Vibrio cholerae infection_Homo sapiens_hsa051100.43442841
91Autoimmune thyroid disease_Homo sapiens_hsa053200.41224575
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40303429
93Cyanoamino acid metabolism_Homo sapiens_hsa004600.39056134
94Graft-versus-host disease_Homo sapiens_hsa053320.37295100
95Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.37065437
96Leishmaniasis_Homo sapiens_hsa051400.36488070
97GnRH signaling pathway_Homo sapiens_hsa049120.35222527
98Pyruvate metabolism_Homo sapiens_hsa006200.35133241
99Steroid hormone biosynthesis_Homo sapiens_hsa001400.34948243
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.33725854
101Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.33689470
102Parkinsons disease_Homo sapiens_hsa050120.32557288
103Shigellosis_Homo sapiens_hsa051310.32357426
104Endometrial cancer_Homo sapiens_hsa052130.30022073
105Phenylalanine metabolism_Homo sapiens_hsa003600.29800198
106Metabolic pathways_Homo sapiens_hsa011000.27408571
107Dorso-ventral axis formation_Homo sapiens_hsa043200.26887803
108ABC transporters_Homo sapiens_hsa020100.26063513
109TNF signaling pathway_Homo sapiens_hsa046680.26005719
110beta-Alanine metabolism_Homo sapiens_hsa004100.25234837
111VEGF signaling pathway_Homo sapiens_hsa043700.24995810
112Fatty acid elongation_Homo sapiens_hsa000620.23254868
113Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.22833154
1142-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.22338227
115Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.22247053
116Staphylococcus aureus infection_Homo sapiens_hsa051500.22019050
117Primary bile acid biosynthesis_Homo sapiens_hsa001200.21799081
118Type I diabetes mellitus_Homo sapiens_hsa049400.21761857
119Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.12864427
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.12235417
121Antigen processing and presentation_Homo sapiens_hsa046120.11183264
122Insulin resistance_Homo sapiens_hsa049310.09546007
123Cysteine and methionine metabolism_Homo sapiens_hsa002700.04740657
124Insulin secretion_Homo sapiens_hsa049110.02043395
125Choline metabolism in cancer_Homo sapiens_hsa052310.01313862
126Biosynthesis of amino acids_Homo sapiens_hsa012300.01055888
127Phosphatidylinositol signaling system_Homo sapiens_hsa040700.00200409

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