

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.42044311 |
| 2 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 6.08673471 |
| 3 | cytidine catabolic process (GO:0006216) | 6.08487519 |
| 4 | cytidine deamination (GO:0009972) | 6.08487519 |
| 5 | cytidine metabolic process (GO:0046087) | 6.08487519 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.29207281 |
| 7 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.14896868 |
| 8 | actin nucleation (GO:0045010) | 5.07507369 |
| 9 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.59322954 |
| 10 | monocyte chemotaxis (GO:0002548) | 4.39585115 |
| 11 | proteasome assembly (GO:0043248) | 4.29944412 |
| 12 | negative regulation of T cell apoptotic process (GO:0070233) | 4.28450555 |
| 13 | positive regulation of B cell differentiation (GO:0045579) | 4.26617339 |
| 14 | regulation of regulatory T cell differentiation (GO:0045589) | 4.06300718 |
| 15 | protein deneddylation (GO:0000338) | 3.82368908 |
| 16 | protein kinase C signaling (GO:0070528) | 3.80361449 |
| 17 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.79689344 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.79265682 |
| 19 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.77796436 |
| 20 | cullin deneddylation (GO:0010388) | 3.77193678 |
| 21 | positive thymic T cell selection (GO:0045059) | 3.73822249 |
| 22 | platelet dense granule organization (GO:0060155) | 3.67882935 |
| 23 | positive regulation of tolerance induction (GO:0002645) | 3.63744754 |
| 24 | regulation of activation of Janus kinase activity (GO:0010533) | 3.60102761 |
| 25 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.48017342 |
| 26 | positive T cell selection (GO:0043368) | 3.47595191 |
| 27 | B cell mediated immunity (GO:0019724) | 3.45789577 |
| 28 | regulation of T cell tolerance induction (GO:0002664) | 3.44574397 |
| 29 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.43815129 |
| 30 | macrophage chemotaxis (GO:0048246) | 3.42850663 |
| 31 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.42451886 |
| 32 | aggressive behavior (GO:0002118) | 3.41539494 |
| 33 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.38615485 |
| 34 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.35363376 |
| 35 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.35267610 |
| 36 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.34999926 |
| 37 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.32489817 |
| 38 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.32320381 |
| 39 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.32320381 |
| 40 | immunoglobulin mediated immune response (GO:0016064) | 3.29881651 |
| 41 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.27150989 |
| 42 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.20824745 |
| 43 | cytolysis (GO:0019835) | 3.20490361 |
| 44 | deoxyribose phosphate catabolic process (GO:0046386) | 3.15471786 |
| 45 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.14994117 |
| 46 | branched-chain amino acid catabolic process (GO:0009083) | 3.14016286 |
| 47 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.12108027 |
| 48 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.11928171 |
| 49 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.10944078 |
| 50 | regulation of tolerance induction (GO:0002643) | 3.09150304 |
| 51 | rRNA modification (GO:0000154) | 3.06499906 |
| 52 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.06438602 |
| 53 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.06438602 |
| 54 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.06438602 |
| 55 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.06314570 |
| 56 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.06314570 |
| 57 | deoxyribonucleotide catabolic process (GO:0009264) | 3.05618381 |
| 58 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.03415806 |
| 59 | negative regulation of ligase activity (GO:0051352) | 3.03415806 |
| 60 | response to interferon-beta (GO:0035456) | 3.02310848 |
| 61 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 3.01708768 |
| 62 | hyperosmotic salinity response (GO:0042538) | 3.01423487 |
| 63 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.99254638 |
| 64 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.99254638 |
| 65 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.96321397 |
| 66 | regulation of T cell apoptotic process (GO:0070232) | 2.95832728 |
| 67 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.95561451 |
| 68 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.95561451 |
| 69 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.93402941 |
| 70 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.92725243 |
| 71 | mitochondrial calcium ion transport (GO:0006851) | 2.92341802 |
| 72 | purine-containing compound salvage (GO:0043101) | 2.90537632 |
| 73 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.90391040 |
| 74 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 2.90190847 |
| 75 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.89844815 |
| 76 | eosinophil chemotaxis (GO:0048245) | 2.89463017 |
| 77 | regulation of B cell differentiation (GO:0045577) | 2.89348206 |
| 78 | regulation of mitochondrial translation (GO:0070129) | 2.87695396 |
| 79 | facial nerve structural organization (GO:0021612) | 2.87583039 |
| 80 | cellular response to interleukin-15 (GO:0071350) | 2.86720585 |
| 81 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.84224986 |
| 82 | deoxyribose phosphate metabolic process (GO:0019692) | 2.81468532 |
| 83 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.80356908 |
| 84 | cellular ketone body metabolic process (GO:0046950) | 2.80095801 |
| 85 | regulation of penile erection (GO:0060405) | 2.79633345 |
| 86 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.75897786 |
| 87 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.73334348 |
| 88 | sequestering of actin monomers (GO:0042989) | 2.72892164 |
| 89 | metallo-sulfur cluster assembly (GO:0031163) | 2.71362620 |
| 90 | iron-sulfur cluster assembly (GO:0016226) | 2.71362620 |
| 91 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.69787467 |
| 92 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.68021788 |
| 93 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 2.67659882 |
| 94 | artery smooth muscle contraction (GO:0014824) | 2.67417674 |
| 95 | negative T cell selection (GO:0043383) | 2.67160061 |
| 96 | ribosomal small subunit assembly (GO:0000028) | 2.66824429 |
| 97 | purine nucleotide salvage (GO:0032261) | 2.65500184 |
| 98 | mast cell degranulation (GO:0043303) | 2.64737706 |
| 99 | mast cell activation involved in immune response (GO:0002279) | 2.64737706 |
| 100 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.63437218 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.46368157 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.16955664 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.09952043 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.93331905 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.63195280 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.43493570 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.38625884 |
| 8 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.32788708 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.15942414 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.96521107 |
| 11 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.79961898 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.63275855 |
| 13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.53300965 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.51082284 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.44698097 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.39181628 |
| 17 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.38148097 |
| 18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.34219956 |
| 19 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.30438286 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.28983401 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.22351123 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.17774982 |
| 23 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.17210446 |
| 24 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.12249948 |
| 25 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.09076440 |
| 26 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.07151832 |
| 27 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.06744321 |
| 28 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.04267175 |
| 29 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.98202666 |
| 30 | MYB_26560356_Chip-Seq_TH2_Human | 1.89808019 |
| 31 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.89754832 |
| 32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.86738301 |
| 33 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83324701 |
| 34 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.78147734 |
| 35 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.76176151 |
| 36 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.72636102 |
| 37 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.68311276 |
| 38 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.67274762 |
| 39 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.61156730 |
| 40 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.60909764 |
| 41 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.60705523 |
| 42 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50875274 |
| 43 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.50807436 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.49542962 |
| 45 | GATA1_22025678_ChIP-Seq_K562_Human | 1.47768464 |
| 46 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.46279717 |
| 47 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.46084168 |
| 48 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.44201435 |
| 49 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.40285088 |
| 50 | UTX_26944678_Chip-Seq_JUKART_Human | 1.40091037 |
| 51 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.38281597 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.37180867 |
| 53 | VDR_22108803_ChIP-Seq_LS180_Human | 1.34690337 |
| 54 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33308707 |
| 55 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.32344804 |
| 56 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.31746335 |
| 57 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.31494326 |
| 58 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.29666807 |
| 59 | MYB_26560356_Chip-Seq_TH1_Human | 1.28665175 |
| 60 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.26432631 |
| 61 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.23900027 |
| 62 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.21649875 |
| 63 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.21121422 |
| 64 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.19652885 |
| 65 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.19312510 |
| 66 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.18278158 |
| 67 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.16342374 |
| 68 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.14796737 |
| 69 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.13694413 |
| 70 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.11857796 |
| 71 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.11277443 |
| 72 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.11163830 |
| 73 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.10851381 |
| 74 | GATA3_26560356_Chip-Seq_TH2_Human | 1.08653732 |
| 75 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.08035850 |
| 76 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.07383736 |
| 77 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.05775958 |
| 78 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04905663 |
| 79 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01847173 |
| 80 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.99277264 |
| 81 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.99237788 |
| 82 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.99003449 |
| 83 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.98864280 |
| 84 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.96014457 |
| 85 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.95404953 |
| 86 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.95290871 |
| 87 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.94493052 |
| 88 | P300_27268052_Chip-Seq_Bcells_Human | 0.94369633 |
| 89 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.93238166 |
| 90 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92547791 |
| 91 | MAF_26560356_Chip-Seq_TH1_Human | 0.90728227 |
| 92 | AR_20517297_ChIP-Seq_VCAP_Human | 0.90542277 |
| 93 | MAF_26560356_Chip-Seq_TH2_Human | 0.90412124 |
| 94 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.89940496 |
| 95 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.89439343 |
| 96 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.87253665 |
| 97 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.86618997 |
| 98 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.82553162 |
| 99 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.80462430 |
| 100 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.77693666 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.61619961 |
| 2 | MP0001873_stomach_inflammation | 3.56746507 |
| 3 | MP0005645_abnormal_hypothalamus_physiol | 3.43730590 |
| 4 | MP0002166_altered_tumor_susceptibility | 3.12473908 |
| 5 | MP0002009_preneoplasia | 2.77710615 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.77689905 |
| 7 | MP0002006_tumorigenesis | 2.60256970 |
| 8 | MP0009697_abnormal_copulation | 2.43920419 |
| 9 | MP0003763_abnormal_thymus_physiology | 2.33509186 |
| 10 | MP0009785_altered_susceptibility_to | 2.29331549 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 2.22345891 |
| 12 | MP0002138_abnormal_hepatobiliary_system | 2.15138587 |
| 13 | MP0001905_abnormal_dopamine_level | 2.03533818 |
| 14 | MP0005000_abnormal_immune_tolerance | 1.94351481 |
| 15 | MP0005025_abnormal_response_to | 1.91820769 |
| 16 | MP0002420_abnormal_adaptive_immunity | 1.89741320 |
| 17 | MP0005646_abnormal_pituitary_gland | 1.89315215 |
| 18 | MP0003866_abnormal_defecation | 1.88992182 |
| 19 | MP0009764_decreased_sensitivity_to | 1.88622494 |
| 20 | MP0006082_CNS_inflammation | 1.85829447 |
| 21 | MP0001800_abnormal_humoral_immune | 1.84777403 |
| 22 | MP0002933_joint_inflammation | 1.83639495 |
| 23 | MP0001819_abnormal_immune_cell | 1.83117646 |
| 24 | MP0002723_abnormal_immune_serum | 1.82734843 |
| 25 | MP0003011_delayed_dark_adaptation | 1.82265124 |
| 26 | MP0001790_abnormal_immune_system | 1.77856308 |
| 27 | MP0005387_immune_system_phenotype | 1.77856308 |
| 28 | MP0002638_abnormal_pupillary_reflex | 1.77684852 |
| 29 | MP0005075_abnormal_melanosome_morpholog | 1.76580359 |
| 30 | MP0005167_abnormal_blood-brain_barrier | 1.72689924 |
| 31 | MP0006035_abnormal_mitochondrial_morpho | 1.70950852 |
| 32 | MP0008058_abnormal_DNA_repair | 1.70119755 |
| 33 | MP0006036_abnormal_mitochondrial_physio | 1.61687622 |
| 34 | MP0010094_abnormal_chromosome_stability | 1.61104418 |
| 35 | MP0000372_irregular_coat_pigmentation | 1.61065270 |
| 36 | MP0002405_respiratory_system_inflammati | 1.58725540 |
| 37 | MP0000689_abnormal_spleen_morphology | 1.58689439 |
| 38 | MP0002452_abnormal_antigen_presenting | 1.53511788 |
| 39 | MP0002398_abnormal_bone_marrow | 1.53211350 |
| 40 | MP0002148_abnormal_hypersensitivity_rea | 1.52712098 |
| 41 | MP0003806_abnormal_nucleotide_metabolis | 1.51467503 |
| 42 | MP0003786_premature_aging | 1.50154680 |
| 43 | MP0004782_abnormal_surfactant_physiolog | 1.48436990 |
| 44 | MP0000716_abnormal_immune_system | 1.45201172 |
| 45 | MP0001853_heart_inflammation | 1.42050431 |
| 46 | MP0002722_abnormal_immune_system | 1.41091938 |
| 47 | MP0003567_abnormal_fetal_cardiomyocyte | 1.39649789 |
| 48 | MP0003724_increased_susceptibility_to | 1.38393196 |
| 49 | MP0000465_gastrointestinal_hemorrhage | 1.37398477 |
| 50 | MP0010155_abnormal_intestine_physiology | 1.36677460 |
| 51 | MP0005253_abnormal_eye_physiology | 1.35304533 |
| 52 | MP0000703_abnormal_thymus_morphology | 1.34700081 |
| 53 | MP0002429_abnormal_blood_cell | 1.28728833 |
| 54 | MP0008007_abnormal_cellular_replicative | 1.27029269 |
| 55 | MP0005464_abnormal_platelet_physiology | 1.24667714 |
| 56 | MP0002277_abnormal_respiratory_mucosa | 1.20705976 |
| 57 | MP0003693_abnormal_embryo_hatching | 1.18676495 |
| 58 | MP0002653_abnormal_ependyma_morphology | 1.12763991 |
| 59 | MP0000685_abnormal_immune_system | 1.11924072 |
| 60 | MP0001845_abnormal_inflammatory_respons | 1.11795025 |
| 61 | MP0003136_yellow_coat_color | 1.07299231 |
| 62 | MP0002419_abnormal_innate_immunity | 1.06316795 |
| 63 | MP0002019_abnormal_tumor_incidence | 1.05820915 |
| 64 | MP0002163_abnormal_gland_morphology | 1.01684693 |
| 65 | MP0002877_abnormal_melanocyte_morpholog | 1.00069941 |
| 66 | MP0008872_abnormal_physiological_respon | 0.99551498 |
| 67 | MP0009763_increased_sensitivity_to | 0.97531543 |
| 68 | MP0002102_abnormal_ear_morphology | 0.96152932 |
| 69 | MP0003436_decreased_susceptibility_to | 0.95570777 |
| 70 | MP0003075_altered_response_to | 0.93941107 |
| 71 | MP0001663_abnormal_digestive_system | 0.92670493 |
| 72 | MP0005379_endocrine/exocrine_gland_phen | 0.92561775 |
| 73 | MP0003448_altered_tumor_morphology | 0.89402309 |
| 74 | MP0008260_abnormal_autophagy | 0.89175394 |
| 75 | MP0001764_abnormal_homeostasis | 0.86607772 |
| 76 | MP0004957_abnormal_blastocyst_morpholog | 0.86415641 |
| 77 | MP0009333_abnormal_splenocyte_physiolog | 0.86341502 |
| 78 | MP0000490_abnormal_crypts_of | 0.84984420 |
| 79 | MP0008469_abnormal_protein_level | 0.82779660 |
| 80 | MP0000613_abnormal_salivary_gland | 0.82624787 |
| 81 | MP0003191_abnormal_cellular_cholesterol | 0.79621250 |
| 82 | MP0005319_abnormal_enzyme/_coenzyme | 0.79169632 |
| 83 | MP0002095_abnormal_skin_pigmentation | 0.76915856 |
| 84 | MP0005220_abnormal_exocrine_pancreas | 0.76126380 |
| 85 | MP0002139_abnormal_hepatobiliary_system | 0.74700962 |
| 86 | MP0003186_abnormal_redox_activity | 0.74139380 |
| 87 | MP0008875_abnormal_xenobiotic_pharmacok | 0.73422649 |
| 88 | MP0008873_increased_physiological_sensi | 0.73291176 |
| 89 | MP0005551_abnormal_eye_electrophysiolog | 0.72309968 |
| 90 | MP0002132_abnormal_respiratory_system | 0.66922776 |
| 91 | MP0010368_abnormal_lymphatic_system | 0.65098461 |
| 92 | MP0003718_maternal_effect | 0.63721441 |
| 93 | MP0005332_abnormal_amino_acid | 0.63333137 |
| 94 | MP0000358_abnormal_cell_content/ | 0.62621921 |
| 95 | MP0005647_abnormal_sex_gland | 0.61714149 |
| 96 | MP0005397_hematopoietic_system_phenotyp | 0.61031072 |
| 97 | MP0001545_abnormal_hematopoietic_system | 0.61031072 |
| 98 | MP0005410_abnormal_fertilization | 0.60462239 |
| 99 | MP0002693_abnormal_pancreas_physiology | 0.60441949 |
| 100 | MP0005535_abnormal_body_temperature | 0.58909601 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.76839988 |
| 2 | Aplastic anemia (HP:0001915) | 5.74787361 |
| 3 | Hepatocellular necrosis (HP:0001404) | 4.70637800 |
| 4 | Type I transferrin isoform profile (HP:0003642) | 4.37658496 |
| 5 | Microvesicular hepatic steatosis (HP:0001414) | 4.28929899 |
| 6 | Hepatic necrosis (HP:0002605) | 4.11502592 |
| 7 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.00067880 |
| 8 | Recurrent cutaneous fungal infections (HP:0011370) | 4.00067880 |
| 9 | T lymphocytopenia (HP:0005403) | 3.91017858 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.83887595 |
| 11 | Panhypogammaglobulinemia (HP:0003139) | 3.83455242 |
| 12 | Autoimmune hemolytic anemia (HP:0001890) | 3.79780170 |
| 13 | Severe combined immunodeficiency (HP:0004430) | 3.77278640 |
| 14 | Agammaglobulinemia (HP:0004432) | 3.74977552 |
| 15 | Mitochondrial inheritance (HP:0001427) | 3.65915458 |
| 16 | Abnormality of T cell number (HP:0011839) | 3.57838530 |
| 17 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.54892367 |
| 18 | Abnormal protein glycosylation (HP:0012346) | 3.52177256 |
| 19 | Abnormal glycosylation (HP:0012345) | 3.52177256 |
| 20 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 3.52177256 |
| 21 | Abnormal protein N-linked glycosylation (HP:0012347) | 3.52177256 |
| 22 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.50191012 |
| 23 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.50191012 |
| 24 | Encephalitis (HP:0002383) | 3.45428221 |
| 25 | Lipid accumulation in hepatocytes (HP:0006561) | 3.36533878 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 3.33221938 |
| 27 | Abnormality of T cells (HP:0002843) | 3.30506245 |
| 28 | Increased IgM level (HP:0003496) | 3.20551869 |
| 29 | Increased CSF lactate (HP:0002490) | 3.11026438 |
| 30 | Recurrent viral infections (HP:0004429) | 3.11000312 |
| 31 | Increased intramyocellular lipid droplets (HP:0012240) | 3.09249717 |
| 32 | Renal Fanconi syndrome (HP:0001994) | 3.02736712 |
| 33 | Prolonged neonatal jaundice (HP:0006579) | 3.01373369 |
| 34 | Combined immunodeficiency (HP:0005387) | 3.01106898 |
| 35 | Pancytopenia (HP:0001876) | 2.99031489 |
| 36 | Autoimmune thrombocytopenia (HP:0001973) | 2.87372634 |
| 37 | Abnormality of T cell physiology (HP:0011840) | 2.84854746 |
| 38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.83148370 |
| 39 | IgG deficiency (HP:0004315) | 2.81804020 |
| 40 | Acute hepatic failure (HP:0006554) | 2.81593187 |
| 41 | Acute necrotizing encephalopathy (HP:0006965) | 2.69865820 |
| 42 | Dicarboxylic aciduria (HP:0003215) | 2.69548746 |
| 43 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.69548746 |
| 44 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.69164536 |
| 45 | Stomach cancer (HP:0012126) | 2.65895493 |
| 46 | Thyroiditis (HP:0100646) | 2.65368413 |
| 47 | Increased serum lactate (HP:0002151) | 2.61323246 |
| 48 | Dyschromatopsia (HP:0007641) | 2.57074121 |
| 49 | Oral leukoplakia (HP:0002745) | 2.55787069 |
| 50 | Increased muscle lipid content (HP:0009058) | 2.52465812 |
| 51 | Abnormality of the prostate (HP:0008775) | 2.52437030 |
| 52 | Abnormality of B cell number (HP:0010975) | 2.51277068 |
| 53 | Amyotrophic lateral sclerosis (HP:0007354) | 2.48719689 |
| 54 | Progressive macrocephaly (HP:0004481) | 2.45359209 |
| 55 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.40202634 |
| 56 | Lactic acidosis (HP:0003128) | 2.39057777 |
| 57 | B lymphocytopenia (HP:0010976) | 2.34570104 |
| 58 | CNS demyelination (HP:0007305) | 2.32148366 |
| 59 | Abnormality of renal resorption (HP:0011038) | 2.31882107 |
| 60 | Exertional dyspnea (HP:0002875) | 2.31593357 |
| 61 | Hypoproteinemia (HP:0003075) | 2.31079207 |
| 62 | Recurrent fungal infections (HP:0002841) | 2.28318437 |
| 63 | Myositis (HP:0100614) | 2.27888954 |
| 64 | Hypergammaglobulinemia (HP:0010702) | 2.24682164 |
| 65 | Meningitis (HP:0001287) | 2.21040284 |
| 66 | Methylmalonic aciduria (HP:0012120) | 2.20734016 |
| 67 | Acute encephalopathy (HP:0006846) | 2.19332227 |
| 68 | Cerebral edema (HP:0002181) | 2.17182653 |
| 69 | Thrombocytosis (HP:0001894) | 2.15900633 |
| 70 | Cellular immunodeficiency (HP:0005374) | 2.14248435 |
| 71 | Reduced antithrombin III activity (HP:0001976) | 2.14231837 |
| 72 | Chronic diarrhea (HP:0002028) | 2.13238187 |
| 73 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.10629852 |
| 74 | Abnormality of midbrain morphology (HP:0002418) | 2.05805428 |
| 75 | Molar tooth sign on MRI (HP:0002419) | 2.05805428 |
| 76 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.04299838 |
| 77 | Abolished electroretinogram (ERG) (HP:0000550) | 2.04068787 |
| 78 | Hypoplasia of the thymus (HP:0000778) | 2.03752526 |
| 79 | Petechiae (HP:0000967) | 2.02929136 |
| 80 | Lymphoma (HP:0002665) | 2.01902101 |
| 81 | Recurrent skin infections (HP:0001581) | 2.00547594 |
| 82 | Emotional lability (HP:0000712) | 1.98568577 |
| 83 | Hemiplegia (HP:0002301) | 1.95346620 |
| 84 | Ketosis (HP:0001946) | 1.94104243 |
| 85 | Cutaneous melanoma (HP:0012056) | 1.92155220 |
| 86 | Short tibia (HP:0005736) | 1.88057810 |
| 87 | Respiratory failure (HP:0002878) | 1.86621509 |
| 88 | Large eyes (HP:0001090) | 1.83775715 |
| 89 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.82854914 |
| 90 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.80531522 |
| 91 | Colitis (HP:0002583) | 1.79673419 |
| 92 | Villous atrophy (HP:0011473) | 1.78045284 |
| 93 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.78045284 |
| 94 | Abnormality of fatty-acid metabolism (HP:0004359) | 1.74938050 |
| 95 | Abnormality of lateral ventricle (HP:0030047) | 1.74136046 |
| 96 | Alveolar cell carcinoma (HP:0006519) | 1.72830124 |
| 97 | Generalized aminoaciduria (HP:0002909) | 1.72321007 |
| 98 | Lymphopenia (HP:0001888) | 1.71321063 |
| 99 | Optic disc pallor (HP:0000543) | 1.71240432 |
| 100 | IgM deficiency (HP:0002850) | 1.69325959 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TIE1 | 5.44644211 |
| 2 | KDR | 4.83933475 |
| 3 | TXK | 4.43629449 |
| 4 | TESK2 | 3.16822378 |
| 5 | ZAK | 2.85573134 |
| 6 | SCYL2 | 2.77504359 |
| 7 | MST4 | 2.60124573 |
| 8 | VRK2 | 2.56212807 |
| 9 | BCKDK | 2.38282602 |
| 10 | FES | 2.31768291 |
| 11 | GRK1 | 1.89120226 |
| 12 | MAP4K2 | 1.88507244 |
| 13 | TESK1 | 1.87985002 |
| 14 | TLK1 | 1.87253620 |
| 15 | TEC | 1.86572410 |
| 16 | NME2 | 1.82713414 |
| 17 | VRK1 | 1.81061673 |
| 18 | TBK1 | 1.75633837 |
| 19 | MAPKAPK3 | 1.72134405 |
| 20 | DAPK1 | 1.64737727 |
| 21 | LIMK1 | 1.62478409 |
| 22 | BMPR1B | 1.60557224 |
| 23 | CDK8 | 1.48357770 |
| 24 | CDC7 | 1.27196505 |
| 25 | ERBB3 | 1.22747977 |
| 26 | MAP4K1 | 1.22477106 |
| 27 | MAP3K12 | 1.19806001 |
| 28 | MAP2K6 | 1.13859787 |
| 29 | TNK2 | 1.13721860 |
| 30 | CDK19 | 1.06361719 |
| 31 | BLK | 1.05051067 |
| 32 | PIK3CG | 1.02906232 |
| 33 | MAP2K7 | 0.99990322 |
| 34 | SYK | 0.99922549 |
| 35 | ADRBK2 | 0.97911679 |
| 36 | MAP3K4 | 0.96456266 |
| 37 | BUB1 | 0.96346930 |
| 38 | PRKCQ | 0.96273042 |
| 39 | FRK | 0.94071028 |
| 40 | BTK | 0.93927415 |
| 41 | BMPR2 | 0.93148892 |
| 42 | CDK9 | 0.93128872 |
| 43 | NUAK1 | 0.91538450 |
| 44 | TAOK3 | 0.88135314 |
| 45 | IKBKB | 0.87342807 |
| 46 | MAP2K3 | 0.85088415 |
| 47 | PBK | 0.83433146 |
| 48 | KIT | 0.82581088 |
| 49 | LCK | 0.82439406 |
| 50 | ZAP70 | 0.81129154 |
| 51 | ITK | 0.76988279 |
| 52 | LYN | 0.76724146 |
| 53 | GRK6 | 0.76526213 |
| 54 | MAP3K5 | 0.74291430 |
| 55 | IKBKE | 0.74120376 |
| 56 | PIM1 | 0.69201381 |
| 57 | CSNK1G3 | 0.65448459 |
| 58 | RIPK4 | 0.63674844 |
| 59 | PIM2 | 0.63607215 |
| 60 | SRPK1 | 0.61579932 |
| 61 | AURKA | 0.59815882 |
| 62 | CSK | 0.59663429 |
| 63 | TRIM28 | 0.54174123 |
| 64 | MYLK | 0.53917866 |
| 65 | EIF2AK1 | 0.53767115 |
| 66 | RPS6KA4 | 0.52305749 |
| 67 | RPS6KA5 | 0.52078430 |
| 68 | ATR | 0.51360629 |
| 69 | CSF1R | 0.50282410 |
| 70 | ACVR1B | 0.49599192 |
| 71 | MAP3K10 | 0.49521296 |
| 72 | MAP2K4 | 0.47816304 |
| 73 | TGFBR2 | 0.46479405 |
| 74 | EPHA4 | 0.46475636 |
| 75 | TGFBR1 | 0.45341881 |
| 76 | MAP3K11 | 0.44252996 |
| 77 | PTK2B | 0.43849231 |
| 78 | CSNK1G1 | 0.43074582 |
| 79 | INSRR | 0.43036709 |
| 80 | CSNK1A1L | 0.42211156 |
| 81 | DAPK3 | 0.40771334 |
| 82 | WNK3 | 0.40449577 |
| 83 | TAOK1 | 0.39184908 |
| 84 | HCK | 0.38054911 |
| 85 | FYN | 0.36416326 |
| 86 | ABL1 | 0.33297804 |
| 87 | CSNK1G2 | 0.32424149 |
| 88 | OXSR1 | 0.32095059 |
| 89 | DYRK1B | 0.31804370 |
| 90 | IRAK4 | 0.31277067 |
| 91 | CSNK2A1 | 0.29853122 |
| 92 | PINK1 | 0.29485443 |
| 93 | AURKB | 0.29392347 |
| 94 | ROCK1 | 0.29119908 |
| 95 | CDK4 | 0.29082605 |
| 96 | CDK7 | 0.28160259 |
| 97 | EIF2AK3 | 0.28114297 |
| 98 | ABL2 | 0.27776186 |
| 99 | CHEK2 | 0.27037386 |
| 100 | TAF1 | 0.26586360 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.66587980 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.52680576 |
| 3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.22908216 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.51773564 |
| 5 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.43727499 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.42674270 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.42665796 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.30256535 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.24336559 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.16663083 |
| 11 | Sulfur relay system_Homo sapiens_hsa04122 | 2.11508863 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.00135954 |
| 13 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.98088772 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.94387734 |
| 15 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.92603325 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 1.81589347 |
| 17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.63336224 |
| 18 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.57790494 |
| 19 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.49262450 |
| 20 | Peroxisome_Homo sapiens_hsa04146 | 1.39570474 |
| 21 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.38916795 |
| 22 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.38292858 |
| 23 | Ribosome_Homo sapiens_hsa03010 | 1.35977991 |
| 24 | DNA replication_Homo sapiens_hsa03030 | 1.35353993 |
| 25 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.31729750 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.29744075 |
| 27 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.25811131 |
| 28 | Asthma_Homo sapiens_hsa05310 | 1.24574260 |
| 29 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.22438599 |
| 30 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.20256055 |
| 31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.16384158 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.16231584 |
| 33 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.15729626 |
| 34 | Shigellosis_Homo sapiens_hsa05131 | 1.13894282 |
| 35 | Alzheimers disease_Homo sapiens_hsa05010 | 1.12571268 |
| 36 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.11261185 |
| 37 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.10979289 |
| 38 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.09109395 |
| 39 | Viral myocarditis_Homo sapiens_hsa05416 | 1.07221860 |
| 40 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.06532646 |
| 41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.02823388 |
| 42 | Homologous recombination_Homo sapiens_hsa03440 | 1.02615243 |
| 43 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.99146317 |
| 44 | Mismatch repair_Homo sapiens_hsa03430 | 0.97435672 |
| 45 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.96626241 |
| 46 | Base excision repair_Homo sapiens_hsa03410 | 0.95331245 |
| 47 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.93677603 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.91270061 |
| 49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.89110482 |
| 50 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.88278948 |
| 51 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.87215952 |
| 52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.83846334 |
| 53 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.83523987 |
| 54 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.82632489 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.81322513 |
| 56 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.79090049 |
| 57 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.78892472 |
| 58 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.78271509 |
| 59 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.77504340 |
| 60 | Phototransduction_Homo sapiens_hsa04744 | 0.77379130 |
| 61 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.76694938 |
| 62 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.76206616 |
| 63 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.76201149 |
| 64 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.75512855 |
| 65 | Measles_Homo sapiens_hsa05162 | 0.74421855 |
| 66 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.74339494 |
| 67 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.74189735 |
| 68 | Spliceosome_Homo sapiens_hsa03040 | 0.71207053 |
| 69 | Other glycan degradation_Homo sapiens_hsa00511 | 0.68396421 |
| 70 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.68339653 |
| 71 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.67933415 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.65329700 |
| 73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62363146 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.62049511 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61458302 |
| 76 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.59300790 |
| 77 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.59219912 |
| 78 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.59152586 |
| 79 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.57159179 |
| 80 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.55910797 |
| 81 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.55571855 |
| 82 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.54654919 |
| 83 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.54426243 |
| 84 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.52492286 |
| 85 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.50733038 |
| 86 | Leishmaniasis_Homo sapiens_hsa05140 | 0.50127348 |
| 87 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.47527045 |
| 88 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.44893744 |
| 89 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.44523272 |
| 90 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.44507841 |
| 91 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.43795284 |
| 92 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.43403614 |
| 93 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.40850807 |
| 94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38750320 |
| 95 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.38685799 |
| 96 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.35694182 |
| 97 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.32789898 |
| 98 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.32121176 |
| 99 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.31028307 |
| 100 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.30921024 |

