LYRM2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)8.25575572
2ATP synthesis coupled proton transport (GO:0015986)8.01129673
3energy coupled proton transport, down electrochemical gradient (GO:0015985)8.01129673
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)7.61525584
5central nervous system myelination (GO:0022010)6.91048930
6axon ensheathment in central nervous system (GO:0032291)6.91048930
7respiratory electron transport chain (GO:0022904)6.45831613
8electron transport chain (GO:0022900)6.28959407
9protein neddylation (GO:0045116)5.81917961
10mitochondrial respiratory chain complex I assembly (GO:0032981)5.17527604
11NADH dehydrogenase complex assembly (GO:0010257)5.17527604
12mitochondrial respiratory chain complex I biogenesis (GO:0097031)5.17527604
13fatty acid elongation (GO:0030497)5.09429919
14chaperone-mediated protein transport (GO:0072321)4.92388115
15protein complex biogenesis (GO:0070271)4.85103390
16long-chain fatty acid biosynthetic process (GO:0042759)4.49111669
17mitochondrial respiratory chain complex assembly (GO:0033108)4.30385361
18GTP biosynthetic process (GO:0006183)4.15283665
19response to pheromone (GO:0019236)4.10343586
20behavioral response to nicotine (GO:0035095)4.04473949
21purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.98832002
22ATP biosynthetic process (GO:0006754)3.94131527
23hydrogen ion transmembrane transport (GO:1902600)3.93933010
24purine nucleoside triphosphate biosynthetic process (GO:0009145)3.90045462
25ribosomal small subunit biogenesis (GO:0042274)3.88086273
26establishment of protein localization to mitochondrial membrane (GO:0090151)3.87151726
27cholesterol biosynthetic process (GO:0006695)3.80932197
28substantia nigra development (GO:0021762)3.69530369
29water-soluble vitamin biosynthetic process (GO:0042364)3.69464056
30cotranslational protein targeting to membrane (GO:0006613)3.66311870
31proton transport (GO:0015992)3.62211600
32viral transcription (GO:0019083)3.57505002
33protein targeting to ER (GO:0045047)3.53550104
34hydrogen transport (GO:0006818)3.53268317
35GPI anchor biosynthetic process (GO:0006506)3.50364429
36SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.48343663
37intraciliary transport (GO:0042073)3.47839196
38translational termination (GO:0006415)3.44420892
39ribonucleoside triphosphate biosynthetic process (GO:0009201)3.42181221
40protein localization to endoplasmic reticulum (GO:0070972)3.41292856
41establishment of protein localization to endoplasmic reticulum (GO:0072599)3.41138685
42epithelial cilium movement (GO:0003351)3.40246382
43sterol biosynthetic process (GO:0016126)3.38747517
44inner mitochondrial membrane organization (GO:0007007)3.35696492
45neuron fate determination (GO:0048664)3.33825274
46mannosylation (GO:0097502)3.33709933
47respiratory chain complex IV assembly (GO:0008535)3.31669907
48UTP biosynthetic process (GO:0006228)3.29825622
49pyrimidine nucleobase catabolic process (GO:0006208)3.28859036
50epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.25508784
51proteasome assembly (GO:0043248)3.25258496
52myelination (GO:0042552)3.22252469
53isoprenoid biosynthetic process (GO:0008299)3.20482710
54GPI anchor metabolic process (GO:0006505)3.18379427
55axon ensheathment (GO:0008366)3.14863030
56ensheathment of neurons (GO:0007272)3.14863030
57nonmotile primary cilium assembly (GO:0035058)3.14051957
58DNA double-strand break processing (GO:0000729)3.11966920
59nucleotide transmembrane transport (GO:1901679)3.04919270
60presynaptic membrane organization (GO:0097090)3.03866661
61regulation of collateral sprouting (GO:0048670)3.02644833
62presynaptic membrane assembly (GO:0097105)3.01384329
63replication fork processing (GO:0031297)3.00069370
64neuron cell-cell adhesion (GO:0007158)2.98524703
65dopamine biosynthetic process (GO:0042416)2.96932102
66preassembly of GPI anchor in ER membrane (GO:0016254)2.96232523
67cellular ketone body metabolic process (GO:0046950)2.95333043
68regulation of glucokinase activity (GO:0033131)2.91358822
69regulation of hexokinase activity (GO:1903299)2.91358822
70detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.89757232
71regulation of catecholamine metabolic process (GO:0042069)2.89750000
72regulation of dopamine metabolic process (GO:0042053)2.89750000
73platelet dense granule organization (GO:0060155)2.89510828
74UTP metabolic process (GO:0046051)2.89282028
75nucleoside triphosphate biosynthetic process (GO:0009142)2.87105928
76negative regulation of neurotransmitter transport (GO:0051589)2.86758783
77ketone body metabolic process (GO:1902224)2.85998039
78cilium morphogenesis (GO:0060271)2.85897800
79cilium movement (GO:0003341)2.83057382
80retinal ganglion cell axon guidance (GO:0031290)2.82915029
81protein K6-linked ubiquitination (GO:0085020)2.81684682
82nucleobase catabolic process (GO:0046113)2.80887733
83cellular protein complex disassembly (GO:0043624)2.80835314
84guanosine-containing compound biosynthetic process (GO:1901070)2.79484988
85negative regulation of protein localization to cell surface (GO:2000009)2.78725452
86cullin deneddylation (GO:0010388)2.78701594
87protein-cofactor linkage (GO:0018065)2.78127012
88nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.77061223
89regulation of feeding behavior (GO:0060259)2.76340221
90cilium organization (GO:0044782)2.74995218
91viral life cycle (GO:0019058)2.74983262
92CTP metabolic process (GO:0046036)2.74229461
93CTP biosynthetic process (GO:0006241)2.74229461
94neurotransmitter uptake (GO:0001504)2.72735671
95response to redox state (GO:0051775)2.72341799
96protein targeting to mitochondrion (GO:0006626)2.72299956
97centriole replication (GO:0007099)2.72281455
98intracellular protein transmembrane import (GO:0044743)2.71651829
99neural nucleus development (GO:0048857)2.71159341
100establishment of integrated proviral latency (GO:0075713)2.70552641
101establishment of viral latency (GO:0019043)2.70389116
102cilium assembly (GO:0042384)2.69673324
103exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.69604421
104maturation of 5.8S rRNA (GO:0000460)2.68859555
105cytochrome complex assembly (GO:0017004)2.65203169
106ATP hydrolysis coupled proton transport (GO:0015991)2.65092629
107energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.65092629
108regulation of nuclear cell cycle DNA replication (GO:0033262)2.64929248
109positive regulation of oligodendrocyte differentiation (GO:0048714)2.64195841
110nucleoside diphosphate phosphorylation (GO:0006165)2.62853295
111transcription elongation from RNA polymerase III promoter (GO:0006385)2.61946084
112termination of RNA polymerase III transcription (GO:0006386)2.61946084
113sequestering of actin monomers (GO:0042989)2.61137584
114translational elongation (GO:0006414)2.59635903
115protein deneddylation (GO:0000338)2.59087827
116establishment of protein localization to mitochondrion (GO:0072655)2.58278021
117aerobic respiration (GO:0009060)2.58067349
118auditory behavior (GO:0031223)2.57858459
119oligodendrocyte differentiation (GO:0048709)2.55389039
120positive regulation of cellular amine metabolic process (GO:0033240)2.55339813
121limb bud formation (GO:0060174)2.54270665
122signal peptide processing (GO:0006465)2.53513804
123neuron remodeling (GO:0016322)2.52421315
124postsynaptic membrane organization (GO:0001941)2.52257163
125G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.49498580
126regulation of pigment cell differentiation (GO:0050932)2.49029762
127regulation of cellular amino acid metabolic process (GO:0006521)2.47788367
128dopamine transport (GO:0015872)2.47214149
129recombinational repair (GO:0000725)2.47084764
130C-terminal protein lipidation (GO:0006501)2.45218796
131negative regulation of transcription regulatory region DNA binding (GO:2000678)2.45111377
132protein localization to cilium (GO:0061512)2.44800908
133translation (GO:0006412)2.44657495
134positive regulation of protein homodimerization activity (GO:0090073)2.44347091
135protein polyglutamylation (GO:0018095)2.43722721
136mitochondrial transport (GO:0006839)2.43433782
137histone H2B ubiquitination (GO:0033523)2.43409862
138double-strand break repair via homologous recombination (GO:0000724)2.43068041
139oxidative phosphorylation (GO:0006119)2.43020796
140protein targeting to membrane (GO:0006612)2.42645193
141mechanosensory behavior (GO:0007638)2.40785779
142regulation of cilium movement (GO:0003352)2.39494558
143kidney morphogenesis (GO:0060993)2.39254105
144resolution of meiotic recombination intermediates (GO:0000712)2.39014591
145DNA deamination (GO:0045006)2.38001714
146anterograde synaptic vesicle transport (GO:0048490)2.37620867
147tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.35373641
148RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.35373641
149neural tube formation (GO:0001841)2.33751692
150ubiquinone metabolic process (GO:0006743)2.33248518
151smoothened signaling pathway (GO:0007224)2.32384528
152L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.32268777
153axoneme assembly (GO:0035082)2.31601833
154reflex (GO:0060004)2.30760844
155negative regulation of DNA-dependent DNA replication (GO:2000104)2.30471093
156chromatin remodeling at centromere (GO:0031055)2.30025755
157startle response (GO:0001964)2.25259123
158tRNA processing (GO:0008033)2.25100509
159ubiquinone biosynthetic process (GO:0006744)2.24566405
160determination of left/right symmetry (GO:0007368)2.23976316
161prenylation (GO:0097354)2.23572790
162protein prenylation (GO:0018342)2.23572790
163anterograde axon cargo transport (GO:0008089)2.21231409
164kynurenine metabolic process (GO:0070189)2.19878868
165DNA damage response, detection of DNA damage (GO:0042769)2.19812171
166reciprocal DNA recombination (GO:0035825)2.18826725

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.13313133
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.94712045
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.92370792
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.89081705
5TAF15_26573619_Chip-Seq_HEK293_Human2.87702983
6EZH2_22144423_ChIP-Seq_EOC_Human2.87064710
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.84200840
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.70062339
9GBX2_23144817_ChIP-Seq_PC3_Human2.67446912
10VDR_22108803_ChIP-Seq_LS180_Human2.51912180
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.37584457
12FUS_26573619_Chip-Seq_HEK293_Human2.28953791
13HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.27445692
14GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.27288364
15EST1_17652178_ChIP-ChIP_JURKAT_Human2.23206474
16BMI1_23680149_ChIP-Seq_NPCS_Mouse2.13070922
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.12345610
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.12264034
19PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.07005078
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.04933808
21POU3F2_20337985_ChIP-ChIP_501MEL_Human1.96690432
22SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.92621266
23CBX2_27304074_Chip-Seq_ESCs_Mouse1.91483052
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.87269419
25SALL1_21062744_ChIP-ChIP_HESCs_Human1.84404081
26EZH2_27304074_Chip-Seq_ESCs_Mouse1.83115882
27JARID2_20064375_ChIP-Seq_MESCs_Mouse1.81742002
28* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.76693352
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.73591297
30SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.71624184
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69090564
32SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.66741056
33MYC_18940864_ChIP-ChIP_HL60_Human1.66392257
34FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.65870878
35ER_23166858_ChIP-Seq_MCF-7_Human1.61199168
36CREB1_15753290_ChIP-ChIP_HEK293T_Human1.60733022
37* P300_19829295_ChIP-Seq_ESCs_Human1.58775607
38OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.57392093
39EED_16625203_ChIP-ChIP_MESCs_Mouse1.55584607
40HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.53295129
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.52383055
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.50327053
43ETS1_20019798_ChIP-Seq_JURKAT_Human1.49255479
44SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.47929856
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.46113398
46SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.45986053
47AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.45252261
48SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.44394169
49MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.43362466
50ELK1_19687146_ChIP-ChIP_HELA_Human1.42280105
51JARID2_20075857_ChIP-Seq_MESCs_Mouse1.40078482
52IRF1_19129219_ChIP-ChIP_H3396_Human1.38662362
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.38560546
54RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.36751688
55SMAD4_21799915_ChIP-Seq_A2780_Human1.36176017
56RNF2_27304074_Chip-Seq_NSC_Mouse1.35294600
57EWS_26573619_Chip-Seq_HEK293_Human1.34911859
58FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.34567474
59TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31275766
60IGF1R_20145208_ChIP-Seq_DFB_Human1.29904078
61TP53_22573176_ChIP-Seq_HFKS_Human1.29844672
62* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29719545
63* AR_25329375_ChIP-Seq_VCAP_Human1.28647356
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.28076040
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.28017707
66IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.26840870
67CBP_20019798_ChIP-Seq_JUKART_Human1.26840870
68EZH2_27294783_Chip-Seq_NPCs_Mouse1.26732951
69POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.25550851
70TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25550851
71* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.25064242
72SUZ12_27294783_Chip-Seq_ESCs_Mouse1.24707468
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.22983420
74ELF1_17652178_ChIP-ChIP_JURKAT_Human1.22704002
75PCGF2_27294783_Chip-Seq_ESCs_Mouse1.21941571
76EZH2_27294783_Chip-Seq_ESCs_Mouse1.20917533
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.20309798
78STAT3_23295773_ChIP-Seq_U87_Human1.19325726
79MTF2_20144788_ChIP-Seq_MESCs_Mouse1.18994555
80NOTCH1_21737748_ChIP-Seq_TLL_Human1.18956755
81* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18836879
82EZH2_18974828_ChIP-Seq_MESCs_Mouse1.18491209
83RNF2_18974828_ChIP-Seq_MESCs_Mouse1.18491209
84BCAT_22108803_ChIP-Seq_LS180_Human1.18383157
85* TAL1_26923725_Chip-Seq_HPCs_Mouse1.18227565
86SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.17489084
87NR3C1_21868756_ChIP-Seq_MCF10A_Human1.16716462
88GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16552949
89ZNF274_21170338_ChIP-Seq_K562_Hela1.15932524
90E2F4_17652178_ChIP-ChIP_JURKAT_Human1.15884240
91FLI1_27457419_Chip-Seq_LIVER_Mouse1.14052622
92PIAS1_25552417_ChIP-Seq_VCAP_Human1.13921040
93SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.13688380
94ELK1_22589737_ChIP-Seq_MCF10A_Human1.13608428
95* TCF4_22108803_ChIP-Seq_LS180_Human1.13305079
96PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.12318778
97BP1_19119308_ChIP-ChIP_Hs578T_Human1.12187707
98HTT_18923047_ChIP-ChIP_STHdh_Human1.11951743
99PCGF2_27294783_Chip-Seq_NPCs_Mouse1.10776851
100EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09798621
101TCF4_23295773_ChIP-Seq_U87_Human1.08463323
102KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07950668
103NANOG_18555785_Chip-Seq_ESCs_Mouse1.07056646
104PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06999899
105* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.05930464
106CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.05435497
107RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05072259
108* SMAD3_21741376_ChIP-Seq_EPCs_Human1.04821315
109FOXA1_25329375_ChIP-Seq_VCAP_Human1.04060999
110FOXA1_27270436_Chip-Seq_PROSTATE_Human1.04060999
111CRX_20693478_ChIP-Seq_RETINA_Mouse1.04054887
112FOXP3_21729870_ChIP-Seq_TREG_Human1.03781626
113MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.03208761
114NANOG_19829295_ChIP-Seq_ESCs_Human1.02998660
115SOX2_19829295_ChIP-Seq_ESCs_Human1.02998660
116SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02679502
117RUNX2_22187159_ChIP-Seq_PCA_Human1.01754685
118CDX2_19796622_ChIP-Seq_MESCs_Mouse1.00909266
119RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.00909087
120CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.00115481
121REST_21632747_ChIP-Seq_MESCs_Mouse1.00007872
122E2F1_18555785_Chip-Seq_ESCs_Mouse0.99821356
123FLI1_21867929_ChIP-Seq_TH2_Mouse0.99370834
124AR_21572438_ChIP-Seq_LNCaP_Human0.99027063
125JUN_21703547_ChIP-Seq_K562_Human0.98531616
126PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.97854317
127P53_22387025_ChIP-Seq_ESCs_Mouse0.96440331
128STAT3_18555785_Chip-Seq_ESCs_Mouse0.96104774
129* CMYC_18555785_Chip-Seq_ESCs_Mouse0.95867500
130WT1_19549856_ChIP-ChIP_CCG9911_Human0.95854779
131TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95213534
132EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.95125539
133VDR_23849224_ChIP-Seq_CD4+_Human0.94668779
134* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93686898
135PRDM14_20953172_ChIP-Seq_ESCs_Human0.93461549
136GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93303619
137ETV2_25802403_ChIP-Seq_MESCs_Mouse0.92640073
138RUNX1_27457419_Chip-Seq_LIVER_Mouse0.89102006
139P300_18555785_Chip-Seq_ESCs_Mouse0.89052838

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.30193695
2MP0001529_abnormal_vocalization4.14133896
3MP0009379_abnormal_foot_pigmentation3.43768788
4MP0001905_abnormal_dopamine_level3.20366862
5MP0000920_abnormal_myelination2.89437536
6MP0006276_abnormal_autonomic_nervous2.86310822
7MP0000569_abnormal_digit_pigmentation2.65516117
8MP0004270_analgesia2.47269778
9MP0005409_darkened_coat_color2.28306337
10MP0002736_abnormal_nociception_after2.26648470
11MP0002272_abnormal_nervous_system2.17888967
12MP0001968_abnormal_touch/_nociception2.13044698
13MP0004142_abnormal_muscle_tone2.10498320
14MP0005423_abnormal_somatic_nervous2.02042170
15MP0002734_abnormal_mechanical_nocicepti2.01438770
16MP0002837_dystrophic_cardiac_calcinosis1.97440668
17MP0003136_yellow_coat_color1.97384535
18MP0003011_delayed_dark_adaptation1.93503607
19MP0001486_abnormal_startle_reflex1.92357427
20MP0004742_abnormal_vestibular_system1.91056596
21MP0005171_absent_coat_pigmentation1.90975450
22MP0001485_abnormal_pinna_reflex1.89949590
23MP0008877_abnormal_DNA_methylation1.89943726
24MP0003787_abnormal_imprinting1.88039551
25MP0002064_seizures1.85842031
26MP0009745_abnormal_behavioral_response1.84750411
27MP0000778_abnormal_nervous_system1.82448765
28MP0001440_abnormal_grooming_behavior1.81395292
29MP0005379_endocrine/exocrine_gland_phen1.79502008
30MP0002638_abnormal_pupillary_reflex1.76897240
31MP0002163_abnormal_gland_morphology1.76544448
32MP0002938_white_spotting1.68394671
33MP0002572_abnormal_emotion/affect_behav1.65080410
34MP0002653_abnormal_ependyma_morphology1.62692403
35MP0003890_abnormal_embryonic-extraembry1.59895387
36MP0009046_muscle_twitch1.59779479
37MP0000372_irregular_coat_pigmentation1.59093768
38MP0002735_abnormal_chemical_nociception1.59059037
39MP0005645_abnormal_hypothalamus_physiol1.57239148
40MP0001970_abnormal_pain_threshold1.55229132
41MP0003283_abnormal_digestive_organ1.55139368
42MP0002822_catalepsy1.51485442
43MP0002067_abnormal_sensory_capabilities1.47535549
44MP0003635_abnormal_synaptic_transmissio1.44450466
45MP0001986_abnormal_taste_sensitivity1.43780626
46MP0003121_genomic_imprinting1.42889785
47MP0002095_abnormal_skin_pigmentation1.42140519
48MP0003690_abnormal_glial_cell1.40983534
49MP0005174_abnormal_tail_pigmentation1.37867593
50MP0003634_abnormal_glial_cell1.33121386
51MP0005551_abnormal_eye_electrophysiolog1.32931652
52MP0002733_abnormal_thermal_nociception1.32077031
53MP0001963_abnormal_hearing_physiology1.31999152
54MP0004924_abnormal_behavior1.31676557
55MP0005386_behavior/neurological_phenoty1.31676557
56MP0003950_abnormal_plasma_membrane1.31528032
57MP0004043_abnormal_pH_regulation1.30590922
58MP0004381_abnormal_hair_follicle1.27738733
59MP0005084_abnormal_gallbladder_morpholo1.27198876
60MP0002063_abnormal_learning/memory/cond1.26506471
61MP0001984_abnormal_olfaction1.26250579
62MP0008995_early_reproductive_senescence1.26123962
63MP0008058_abnormal_DNA_repair1.25977034
64MP0006072_abnormal_retinal_apoptosis1.25393014
65MP0003122_maternal_imprinting1.25324821
66MP0002234_abnormal_pharynx_morphology1.25103679
67MP0010386_abnormal_urinary_bladder1.25050567
68MP0001188_hyperpigmentation1.24397213
69MP0000427_abnormal_hair_cycle1.23599675
70MP0002184_abnormal_innervation1.21355104
71MP0002229_neurodegeneration1.18301926
72MP0005408_hypopigmentation1.17499196
73MP0001293_anophthalmia1.16938807
74MP0006036_abnormal_mitochondrial_physio1.15964775
75MP0005187_abnormal_penis_morphology1.14735313
76MP0004145_abnormal_muscle_electrophysio1.14499551
77MP0002928_abnormal_bile_duct1.13418163
78MP0000026_abnormal_inner_ear1.13065174
79MP0005646_abnormal_pituitary_gland1.12168564
80MP0000647_abnormal_sebaceous_gland1.10907496
81MP0005410_abnormal_fertilization1.10582889
82MP0005499_abnormal_olfactory_system1.09440550
83MP0005394_taste/olfaction_phenotype1.09440550
84MP0008875_abnormal_xenobiotic_pharmacok1.07954344
85MP0002876_abnormal_thyroid_physiology1.07034507
86MP0002751_abnormal_autonomic_nervous1.06033139
87MP0002557_abnormal_social/conspecific_i1.04427018
88MP0001501_abnormal_sleep_pattern1.04275889
89MP0002882_abnormal_neuron_morphology1.04230517
90MP0004215_abnormal_myocardial_fiber1.03711815
91MP0002752_abnormal_somatic_nervous1.02944443
92MP0000631_abnormal_neuroendocrine_gland1.01818345
93MP0000462_abnormal_digestive_system1.00368631
94MP0006292_abnormal_olfactory_placode0.99726651
95MP0008789_abnormal_olfactory_epithelium0.99525639
96MP0002160_abnormal_reproductive_system0.99436835
97MP0003937_abnormal_limbs/digits/tail_de0.99080247
98MP0001324_abnormal_eye_pigmentation0.97704303
99MP0002066_abnormal_motor_capabilities/c0.97625601
100MP0008872_abnormal_physiological_respon0.96756269
101MP0005451_abnormal_body_composition0.96313094
102MP0003329_amyloid_beta_deposits0.96033531
103MP0004147_increased_porphyrin_level0.95644897
104MP0003938_abnormal_ear_development0.95292322
105MP0002102_abnormal_ear_morphology0.94746811
106MP0005391_vision/eye_phenotype0.91463883
107MP0001727_abnormal_embryo_implantation0.90116291
108MP0003646_muscle_fatigue0.89875953
109MP0005253_abnormal_eye_physiology0.89518010
110MP0002909_abnormal_adrenal_gland0.88938229
111MP0004859_abnormal_synaptic_plasticity0.88937613
112MP0000049_abnormal_middle_ear0.87962179
113MP0001346_abnormal_lacrimal_gland0.87840693
114MP0001502_abnormal_circadian_rhythm0.86852197
115MP0004885_abnormal_endolymph0.86408941
116MP0004036_abnormal_muscle_relaxation0.85933674
117MP0005389_reproductive_system_phenotype0.85864923
118MP0004134_abnormal_chest_morphology0.85291780
119MP0002090_abnormal_vision0.84375491
120MP0006035_abnormal_mitochondrial_morpho0.84317436
121MP0004133_heterotaxia0.84282073
122MP0003119_abnormal_digestive_system0.84273791
123MP0003786_premature_aging0.83808886
124MP0003186_abnormal_redox_activity0.82842497
125MP0003718_maternal_effect0.81735113
126MP0000955_abnormal_spinal_cord0.80377807
127MP0002277_abnormal_respiratory_mucosa0.79079041
128MP0005075_abnormal_melanosome_morpholog0.77376347
129MP0003137_abnormal_impulse_conducting0.74630376
130MP0000749_muscle_degeneration0.73003346
131MP0003195_calcinosis0.72173033
132MP0005195_abnormal_posterior_eye0.71076564
133MP0003631_nervous_system_phenotype0.70736283
134MP0001664_abnormal_digestion0.70394225
135MP0003724_increased_susceptibility_to0.66248973
136MP0003806_abnormal_nucleotide_metabolis0.65360640
137MP0009697_abnormal_copulation0.64411078

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)7.12052067
2Abnormal mitochondria in muscle tissue (HP:0008316)6.23210930
3Mitochondrial inheritance (HP:0001427)5.99491611
4Progressive macrocephaly (HP:0004481)5.95638893
5Acute encephalopathy (HP:0006846)5.70209603
6Hepatocellular necrosis (HP:0001404)4.98737403
7Renal Fanconi syndrome (HP:0001994)4.87787733
8Increased hepatocellular lipid droplets (HP:0006565)4.87236501
9Increased CSF lactate (HP:0002490)4.78162689
10Lipid accumulation in hepatocytes (HP:0006561)4.25647081
11Leukodystrophy (HP:0002415)4.24635284
12Hepatic necrosis (HP:0002605)4.19258589
13True hermaphroditism (HP:0010459)4.10054471
14Pancreatic cysts (HP:0001737)4.08043715
15Pancreatic fibrosis (HP:0100732)4.02731167
16Congenital nonbullous ichthyosiform erythroderma (HP:0007479)4.00469194
173-Methylglutaconic aciduria (HP:0003535)3.82413926
18Parakeratosis (HP:0001036)3.82347042
19Cerebral edema (HP:0002181)3.76015186
20Optic disc pallor (HP:0000543)3.74942219
21Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.72699679
22Abnormality of glycolysis (HP:0004366)3.60076500
23Increased serum pyruvate (HP:0003542)3.60076500
24Respiratory failure (HP:0002878)3.51488799
25Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.39707463
26Nephronophthisis (HP:0000090)3.34671097
27Abnormality of renal resorption (HP:0011038)3.21627854
28Exercise intolerance (HP:0003546)3.20156667
29Increased intramyocellular lipid droplets (HP:0012240)3.16817057
30Exertional dyspnea (HP:0002875)3.09726381
31Congenital ichthyosiform erythroderma (HP:0007431)2.92411847
32Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.86861284
33Degeneration of the lateral corticospinal tracts (HP:0002314)2.86861284
34Lactic acidosis (HP:0003128)2.81471420
35Abnormality of the renal medulla (HP:0100957)2.81275384
36Neurofibrillary tangles (HP:0002185)2.76018824
37Type II lissencephaly (HP:0007260)2.74066730
38Hypothermia (HP:0002045)2.73290025
39Sclerocornea (HP:0000647)2.72554405
40Decreased activity of mitochondrial respiratory chain (HP:0008972)2.69412120
41Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.69412120
42Abnormality of the renal cortex (HP:0011035)2.66023837
43Congenital stationary night blindness (HP:0007642)2.58888190
44X-linked dominant inheritance (HP:0001423)2.56220659
45Increased muscle lipid content (HP:0009058)2.51978838
46Increased serum lactate (HP:0002151)2.50271636
47Medial flaring of the eyebrow (HP:0010747)2.49163619
48Septate vagina (HP:0001153)2.49092168
49Abolished electroretinogram (ERG) (HP:0000550)2.48550112
50Large for gestational age (HP:0001520)2.47682611
51Abnormality of cells of the erythroid lineage (HP:0012130)2.46975604
52Male pseudohermaphroditism (HP:0000037)2.45857266
53Aplasia/Hypoplasia of the tongue (HP:0010295)2.45638991
54Chronic hepatic failure (HP:0100626)2.44305663
55Respiratory difficulties (HP:0002880)2.43503600
56Renal cortical cysts (HP:0000803)2.39974051
57Intestinal atresia (HP:0011100)2.34495473
58Cystic liver disease (HP:0006706)2.34148900
59Neuroendocrine neoplasm (HP:0100634)2.33511453
60Retinal dysplasia (HP:0007973)2.33046607
61Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.29548212
62Abnormality of alanine metabolism (HP:0010916)2.29548212
63Hyperalaninemia (HP:0003348)2.29548212
64Hyperphosphaturia (HP:0003109)2.26387875
65Anencephaly (HP:0002323)2.24568605
66Abnormality of urine glucose concentration (HP:0011016)2.23583762
67Glycosuria (HP:0003076)2.23583762
68Gait imbalance (HP:0002141)2.20236913
69Pheochromocytoma (HP:0002666)2.19623670
70Sensory axonal neuropathy (HP:0003390)2.18023087
71Cerebral hemorrhage (HP:0001342)2.15901541
72Cerebellar dysplasia (HP:0007033)2.15653095
73Congenital, generalized hypertrichosis (HP:0004540)2.14171433
74Hyperglycinemia (HP:0002154)2.11071233
75Postaxial foot polydactyly (HP:0001830)2.09973957
76Congenital primary aphakia (HP:0007707)2.08083098
77Polydipsia (HP:0001959)2.06217847
78Abnormal drinking behavior (HP:0030082)2.06217847
79Occipital encephalocele (HP:0002085)2.05659569
80Vaginal atresia (HP:0000148)2.04688606
81Myokymia (HP:0002411)2.03853782
82Tubular atrophy (HP:0000092)2.03748533
83Macrocytic anemia (HP:0001972)2.02942200
84Furrowed tongue (HP:0000221)2.02619224
85Abnormal number of erythroid precursors (HP:0012131)2.02614528
86Congenital hepatic fibrosis (HP:0002612)2.02261016
87Patchy hypopigmentation of hair (HP:0011365)2.01329501
88Limb dystonia (HP:0002451)2.00534050
89Genital tract atresia (HP:0001827)2.00375998
90Hypomagnesemia (HP:0002917)2.00316809
91Pendular nystagmus (HP:0012043)1.99743982
92Hypoplastic left heart (HP:0004383)1.99569484
93Gastrointestinal atresia (HP:0002589)1.98538145
94Aplasia/Hypoplasia of the uvula (HP:0010293)1.97901681
95Postaxial hand polydactyly (HP:0001162)1.97066869
96Inability to walk (HP:0002540)1.96612532
97CNS demyelination (HP:0007305)1.96390625
98Abnormal ciliary motility (HP:0012262)1.94779369
99Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.94160220
100Nephrogenic diabetes insipidus (HP:0009806)1.93542020
101Methylmalonic aciduria (HP:0012120)1.93338825
102Abnormality of the axillary hair (HP:0100134)1.92572691
103Abnormality of secondary sexual hair (HP:0009888)1.92572691
104Optic nerve hypoplasia (HP:0000609)1.92103791
105Abnormality of the labia minora (HP:0012880)1.91385305
106Hemiparesis (HP:0001269)1.90638141
107Cerebral hypomyelination (HP:0006808)1.90337209
108Abnormality of the pons (HP:0007361)1.87949950
109Colon cancer (HP:0003003)1.87671756
110Abnormal urine phosphate concentration (HP:0012599)1.86557993
111Peripheral hypomyelination (HP:0007182)1.85986145
112Degeneration of anterior horn cells (HP:0002398)1.85658464
113Abnormality of the anterior horn cell (HP:0006802)1.85658464
114Progressive inability to walk (HP:0002505)1.85469765
115Abnormal hair whorl (HP:0010721)1.85131478
116Preaxial hand polydactyly (HP:0001177)1.84989739
117Abnormal pupillary function (HP:0007686)1.84540933
118Emotional lability (HP:0000712)1.84072048
119Lissencephaly (HP:0001339)1.83971151
120Volvulus (HP:0002580)1.83761711
121Anophthalmia (HP:0000528)1.82665406
122Ketoacidosis (HP:0001993)1.82236253
123Septo-optic dysplasia (HP:0100842)1.81043710
124Anomalous pulmonary venous return (HP:0010772)1.75453125
125Attenuation of retinal blood vessels (HP:0007843)1.74565002
126Hypoplasia of the pons (HP:0012110)1.74320598
127Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.74075442
128Abnormal respiratory motile cilium physiology (HP:0012261)1.73446537
129Poor coordination (HP:0002370)1.72471335
130Dandy-Walker malformation (HP:0001305)1.72065492
131Concave nail (HP:0001598)1.70924283
132Cerebral inclusion bodies (HP:0100314)1.70720058
133Rhinitis (HP:0012384)1.70601489
134Rib fusion (HP:0000902)1.69705996
135Renal tubular dysfunction (HP:0000124)1.69333385
136Abnormal respiratory motile cilium morphology (HP:0005938)1.68997503
137Abnormal respiratory epithelium morphology (HP:0012253)1.68997503
138Abnormality of the corticospinal tract (HP:0002492)1.68205702
139Amniotic constriction ring (HP:0009775)1.66145323
140Abnormality of placental membranes (HP:0011409)1.66145323
141Adrenal hypoplasia (HP:0000835)1.65750172
142Absent septum pellucidum (HP:0001331)1.65438421
143Short tibia (HP:0005736)1.65054247
144White forelock (HP:0002211)1.63656635
145Aplasia/Hypoplasia of the tibia (HP:0005772)1.62237941
146Blindness (HP:0000618)1.61890663
147Muscle hypertrophy of the lower extremities (HP:0008968)1.61857923
148Hypoplastic heart (HP:0001961)1.61614961
149Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.60500669
150Hepatosplenomegaly (HP:0001433)1.59934528
151Hyperventilation (HP:0002883)1.57038867
152Abnormality of midbrain morphology (HP:0002418)1.56924205
153Molar tooth sign on MRI (HP:0002419)1.56924205
154Dynein arm defect of respiratory motile cilia (HP:0012255)1.56712009
155Absent/shortened dynein arms (HP:0200106)1.56712009
156Abnormality of the septum pellucidum (HP:0007375)1.56167159
157Methylmalonic acidemia (HP:0002912)1.54662616
158Pallor (HP:0000980)1.54659131
159Hypoplastic pelvis (HP:0008839)1.53973994

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK393.79977649
2FRK3.79073068
3STK163.20554272
4OXSR12.61417256
5BCR2.60193263
6MST42.59759423
7TNIK2.55276497
8ARAF2.54347898
9PBK2.47493920
10CASK2.38012097
11NME12.34428770
12PINK12.24108464
13MAP4K22.20866122
14BMPR1B2.08870734
15MAP3K122.01447769
16LIMK11.98935747
17WNK41.92109902
18WEE11.89818603
19GRK71.87542865
20NME21.81687812
21ACVR1B1.79998757
22PNCK1.79749384
23TRIM281.78874631
24MKNK21.74802852
25MAPKAPK51.70353759
26ZAK1.69974293
27NUAK11.68926626
28PKN11.68623428
29DYRK21.68346902
30UHMK11.66741908
31INSRR1.65135831
32MUSK1.63986705
33GRK11.53245897
34VRK11.48651081
35MAPK131.40268964
36GRK51.40105862
37MARK11.36032946
38PAK31.34741454
39CSNK1G31.34671841
40CAMK2B1.32773382
41CDK191.31410613
42MAPK151.25309540
43BMPR21.24061183
44MYLK1.23319031
45STK38L1.22418057
46BRSK21.19492730
47PLK31.19058243
48PIM21.17804394
49PLK41.15641199
50EPHB11.13594293
51PRKCG1.13247234
52CAMKK21.12234808
53BUB11.11835996
54ADRBK21.10798030
55BCKDK1.08460463
56VRK21.03590969
57CAMK2D1.02571471
58EIF2AK31.00519068
59TAOK30.99471778
60BRAF0.98838697
61MAP2K70.98742779
62FGR0.97878566
63WNK30.95894440
64OBSCN0.94150809
65TSSK60.94044193
66ROCK20.92625633
67CAMK2A0.88705470
68RPS6KA50.88199413
69PASK0.87334883
70CSNK1G10.84482026
71CCNB10.83450511
72PLK10.81251228
73CDC70.81136742
74PRKCE0.79850784
75CSNK1A1L0.79635881
76CAMK2G0.79308465
77CSNK1G20.79139779
78TGFBR10.78877077
79PLK20.78197740
80DAPK20.76236897
81MKNK10.75601360
82SRPK10.75408677
83MST1R0.74502218
84NEK10.74132639
85ADRBK10.73678161
86EPHA30.73393428
87FES0.70789096
88DYRK30.70538661
89NTRK30.67200505
90TLK10.66601810
91STK30.65019738
92IRAK10.64676750
93PRKCQ0.62627860
94CDK80.62556348
95SIK30.60654916
96TESK20.60283572
97MET0.60018593
98FGFR20.59716884
99TEC0.58346173
100CDK140.58110750
101IRAK20.57258803
102CHEK20.57205118
103RIPK40.56857150
104CLK10.56251765
105TAF10.54888083
106NEK60.54134817
107MOS0.53517543
108ATR0.53467709
109MINK10.53466058
110NTRK20.51833592
111CDK50.51680861
112EPHB20.51635630
113PIK3CA0.51230309
114ABL20.49819967
115PRKG10.49520631
116IRAK40.49246979
117TTK0.49034961
118PRKACA0.48321306
119YES10.48277206
120CDK180.48081691
121CSNK1A10.46722846
122CDK30.46135835
123MAP3K40.45321760
124DYRK1A0.44091762
125CDK150.43691382
126ATM0.43515798
127EIF2AK20.43180680
128MAPK40.42458315
129CDK11A0.41663281
130PDK20.39881726
131TXK0.38943693
132TESK10.37587595
133CSNK1E0.37525323
134NTRK10.36615613
135EIF2AK10.35104657
136ILK0.34992806
137EPHA40.34721322
138PRKACB0.34541117
139TIE10.33881796
140ERBB30.33372397
141NLK0.32751099
142CSNK2A10.32160393
143PHKG10.31901405
144PHKG20.31901405

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.88661425
2Parkinsons disease_Homo sapiens_hsa050124.88785886
3Alzheimers disease_Homo sapiens_hsa050103.86747023
4Protein export_Homo sapiens_hsa030603.73234633
5Ribosome_Homo sapiens_hsa030103.51636945
6Huntingtons disease_Homo sapiens_hsa050163.39461829
7Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.37880634
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049323.06843454
9Proteasome_Homo sapiens_hsa030502.90959417
10Fatty acid elongation_Homo sapiens_hsa000622.63934192
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.59488262
12Steroid biosynthesis_Homo sapiens_hsa001002.29407684
13Cardiac muscle contraction_Homo sapiens_hsa042602.28150514
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.03613930
15RNA polymerase_Homo sapiens_hsa030202.03378502
16Fanconi anemia pathway_Homo sapiens_hsa034601.88474487
17Sulfur metabolism_Homo sapiens_hsa009201.86674949
18Ether lipid metabolism_Homo sapiens_hsa005651.80411902
19Collecting duct acid secretion_Homo sapiens_hsa049661.75183163
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.65700797
21Nitrogen metabolism_Homo sapiens_hsa009101.47340273
22SNARE interactions in vesicular transport_Homo sapiens_hsa041301.37728351
23Tryptophan metabolism_Homo sapiens_hsa003801.33562711
24Vibrio cholerae infection_Homo sapiens_hsa051101.33224705
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.27912218
26Selenocompound metabolism_Homo sapiens_hsa004501.23564083
27Primary bile acid biosynthesis_Homo sapiens_hsa001201.20699968
28Serotonergic synapse_Homo sapiens_hsa047261.16920693
29Linoleic acid metabolism_Homo sapiens_hsa005911.15054819
30Mismatch repair_Homo sapiens_hsa034301.12070846
31Nicotine addiction_Homo sapiens_hsa050331.10259724
32Sphingolipid metabolism_Homo sapiens_hsa006001.07308605
33Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.05708278
34Caffeine metabolism_Homo sapiens_hsa002321.04624532
35Arachidonic acid metabolism_Homo sapiens_hsa005901.04148255
36Rheumatoid arthritis_Homo sapiens_hsa053231.02212468
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.94920765
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.93245098
39One carbon pool by folate_Homo sapiens_hsa006700.92868416
40Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.92321116
41beta-Alanine metabolism_Homo sapiens_hsa004100.90881857
42Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.90397655
43alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.90159072
44Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87101292
45Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.86544231
46Basal transcription factors_Homo sapiens_hsa030220.86407010
47Chemical carcinogenesis_Homo sapiens_hsa052040.83528415
48Butanoate metabolism_Homo sapiens_hsa006500.81529525
49Insulin secretion_Homo sapiens_hsa049110.81216213
50Autoimmune thyroid disease_Homo sapiens_hsa053200.80372545
51Phototransduction_Homo sapiens_hsa047440.79363452
52Metabolic pathways_Homo sapiens_hsa011000.79249113
53GABAergic synapse_Homo sapiens_hsa047270.79210267
54RNA transport_Homo sapiens_hsa030130.78462556
55Pyrimidine metabolism_Homo sapiens_hsa002400.77153328
56Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.77125160
57Cysteine and methionine metabolism_Homo sapiens_hsa002700.76229668
58Vitamin B6 metabolism_Homo sapiens_hsa007500.75987303
59Histidine metabolism_Homo sapiens_hsa003400.70120156
60Retinol metabolism_Homo sapiens_hsa008300.69577322
61Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.69042961
62Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.67928388
63Glutathione metabolism_Homo sapiens_hsa004800.67609375
64Fatty acid metabolism_Homo sapiens_hsa012120.66981725
65Allograft rejection_Homo sapiens_hsa053300.66842620
66Phagosome_Homo sapiens_hsa041450.66786254
67Fatty acid degradation_Homo sapiens_hsa000710.65879806
68Pentose and glucuronate interconversions_Homo sapiens_hsa000400.64635390
69Graft-versus-host disease_Homo sapiens_hsa053320.63048956
70Taste transduction_Homo sapiens_hsa047420.62571983
71Glutamatergic synapse_Homo sapiens_hsa047240.61917742
72Olfactory transduction_Homo sapiens_hsa047400.61145214
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.60697758
74Purine metabolism_Homo sapiens_hsa002300.59467058
75Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.59446660
76Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58726267
77Axon guidance_Homo sapiens_hsa043600.58326291
78Morphine addiction_Homo sapiens_hsa050320.55988199
79Base excision repair_Homo sapiens_hsa034100.55871416
80Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.53950223
81Circadian rhythm_Homo sapiens_hsa047100.53629194
82Regulation of autophagy_Homo sapiens_hsa041400.50651855
83Long-term depression_Homo sapiens_hsa047300.50351945
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.49271508
85Synaptic vesicle cycle_Homo sapiens_hsa047210.49045790
86Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.47841861
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47458718
88Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45545864
89Propanoate metabolism_Homo sapiens_hsa006400.45215589
90Cocaine addiction_Homo sapiens_hsa050300.45170543
91Hedgehog signaling pathway_Homo sapiens_hsa043400.44944409
92Tyrosine metabolism_Homo sapiens_hsa003500.43891362
93DNA replication_Homo sapiens_hsa030300.43525451
94Asthma_Homo sapiens_hsa053100.42655917
95Basal cell carcinoma_Homo sapiens_hsa052170.42621588
96Circadian entrainment_Homo sapiens_hsa047130.42041757
97Oocyte meiosis_Homo sapiens_hsa041140.41928233
98Spliceosome_Homo sapiens_hsa030400.41023971
99Arginine and proline metabolism_Homo sapiens_hsa003300.40472065
100Dopaminergic synapse_Homo sapiens_hsa047280.39343490
101Sulfur relay system_Homo sapiens_hsa041220.38248975
102Nucleotide excision repair_Homo sapiens_hsa034200.37910536
103Homologous recombination_Homo sapiens_hsa034400.37455436
104Peroxisome_Homo sapiens_hsa041460.37434453
105African trypanosomiasis_Homo sapiens_hsa051430.36850841
106Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.34414830
107Fat digestion and absorption_Homo sapiens_hsa049750.32295391
108Alcoholism_Homo sapiens_hsa050340.32191150
109Type I diabetes mellitus_Homo sapiens_hsa049400.32027834
110Glycerolipid metabolism_Homo sapiens_hsa005610.31816284
111Maturity onset diabetes of the young_Homo sapiens_hsa049500.31074603
112Pyruvate metabolism_Homo sapiens_hsa006200.30205966
113Cholinergic synapse_Homo sapiens_hsa047250.29713593
114Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.28415292
115Renin secretion_Homo sapiens_hsa049240.28062882
116Amphetamine addiction_Homo sapiens_hsa050310.27090893
117Folate biosynthesis_Homo sapiens_hsa007900.26454243
118Vascular smooth muscle contraction_Homo sapiens_hsa042700.24401782
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.23576066
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.23255249
121Salivary secretion_Homo sapiens_hsa049700.22288208
122Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.22287265
123Pancreatic secretion_Homo sapiens_hsa049720.21549355
124Calcium signaling pathway_Homo sapiens_hsa040200.18367538
125Non-homologous end-joining_Homo sapiens_hsa034500.18006500
126RNA degradation_Homo sapiens_hsa030180.15561124
127Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.14113153
128N-Glycan biosynthesis_Homo sapiens_hsa005100.12145562
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.12088453
130Steroid hormone biosynthesis_Homo sapiens_hsa001400.09969030
131Malaria_Homo sapiens_hsa051440.09934245
132Other glycan degradation_Homo sapiens_hsa005110.09769224
133Mineral absorption_Homo sapiens_hsa049780.09690443
134Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.08960856
135Lysosome_Homo sapiens_hsa041420.08571504

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