MAATS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)7.60822871
2cilium movement (GO:0003341)7.55805111
3axonemal dynein complex assembly (GO:0070286)6.84749262
4axoneme assembly (GO:0035082)6.75634187
5epithelial cilium movement (GO:0003351)6.27554668
6epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.25129868
7motile cilium assembly (GO:0044458)5.09365364
8primary alcohol catabolic process (GO:0034310)5.07995313
9regulation of microtubule-based movement (GO:0060632)5.07956932
10GTP biosynthetic process (GO:0006183)4.93391821
11left/right axis specification (GO:0070986)4.62084394
12microtubule-based movement (GO:0007018)4.57602907
13vitamin transmembrane transport (GO:0035461)4.56471959
14negative regulation of keratinocyte proliferation (GO:0010839)4.53916146
15intraciliary transport (GO:0042073)4.46029624
16microtubule depolymerization (GO:0007019)4.40663425
17acrosome reaction (GO:0007340)4.38539227
18ethanol metabolic process (GO:0006067)4.17842768
19multicellular organism reproduction (GO:0032504)4.14232438
20lung epithelium development (GO:0060428)4.13264428
21nucleoside diphosphate phosphorylation (GO:0006165)4.12267770
22cilium organization (GO:0044782)4.05710594
23cilium assembly (GO:0042384)4.04846643
24diterpenoid biosynthetic process (GO:0016102)4.04280425
25ventricular system development (GO:0021591)4.00815856
26regulation of cilium movement (GO:0003352)3.95522729
27UTP biosynthetic process (GO:0006228)3.95382773
28lateral ventricle development (GO:0021670)3.84317042
29determination of left/right symmetry (GO:0007368)3.82288932
30piRNA metabolic process (GO:0034587)3.70767248
31sensory perception of smell (GO:0007608)3.68363729
32determination of bilateral symmetry (GO:0009855)3.67227635
33DNA strand renaturation (GO:0000733)3.61575235
34specification of symmetry (GO:0009799)3.58754785
35response to xenobiotic stimulus (GO:0009410)3.58428648
36lateral sprouting from an epithelium (GO:0060601)3.54780229
37female gonad development (GO:0008585)3.53066939
38guanosine-containing compound biosynthetic process (GO:1901070)3.49044380
39negative regulation of T cell differentiation in thymus (GO:0033085)3.48267441
40sperm motility (GO:0030317)3.44996290
41establishment of tissue polarity (GO:0007164)3.43848335
42establishment of planar polarity (GO:0001736)3.43848335
43pyrimidine-containing compound transmembrane transport (GO:0072531)3.39588716
44protein polyglutamylation (GO:0018095)3.36044155
45one-carbon compound transport (GO:0019755)3.34068523
46centriole assembly (GO:0098534)3.30599311
47retinoic acid metabolic process (GO:0042573)3.29769828
48CTP metabolic process (GO:0046036)3.28961458
49CTP biosynthetic process (GO:0006241)3.28961458
50cellular component assembly involved in morphogenesis (GO:0010927)3.25502689
51cilium morphogenesis (GO:0060271)3.24589095
52positive regulation of smoothened signaling pathway (GO:0045880)3.22244726
53terpenoid biosynthetic process (GO:0016114)3.21663325
54sperm capacitation (GO:0048240)3.21301765
55establishment of apical/basal cell polarity (GO:0035089)3.20666217
56establishment of monopolar cell polarity (GO:0061162)3.19148824
57establishment or maintenance of monopolar cell polarity (GO:0061339)3.19148824
58UTP metabolic process (GO:0046051)3.17924930
59DNA methylation involved in gamete generation (GO:0043046)3.17796901
60male meiosis I (GO:0007141)3.15922043
61photoreceptor cell maintenance (GO:0045494)3.14043388
62microtubule polymerization or depolymerization (GO:0031109)3.13354811
63regulation of interleukin-5 production (GO:0032674)3.12788089
64pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.12116777
65negative regulation of inclusion body assembly (GO:0090084)3.11548952
66glomerular epithelial cell development (GO:0072310)3.10919974
67protein localization to cilium (GO:0061512)3.09468485
68regulation of male gonad development (GO:2000018)3.09247477
69male meiosis (GO:0007140)3.08349016
70ethanol oxidation (GO:0006069)3.06483787
71limb bud formation (GO:0060174)3.04782574
72single fertilization (GO:0007338)3.04247906
73cytoplasmic microtubule organization (GO:0031122)3.03731463
74sperm-egg recognition (GO:0035036)2.99963848
75cellular response to gamma radiation (GO:0071480)2.98735416
76aldehyde catabolic process (GO:0046185)2.98109340
77regulation of timing of cell differentiation (GO:0048505)2.95379666
78negative regulation of immunoglobulin mediated immune response (GO:0002890)2.92768142
79negative regulation of B cell mediated immunity (GO:0002713)2.92768142
80nonmotile primary cilium assembly (GO:0035058)2.91613441
81cell wall macromolecule metabolic process (GO:0044036)2.89751025
82cell wall macromolecule catabolic process (GO:0016998)2.89751025
83acrosome assembly (GO:0001675)2.88458843
84microtubule bundle formation (GO:0001578)2.86138859
85superoxide anion generation (GO:0042554)2.85863884
86exogenous drug catabolic process (GO:0042738)2.85133686
87limb development (GO:0060173)2.81463270
88appendage development (GO:0048736)2.81463270
89fusion of sperm to egg plasma membrane (GO:0007342)2.81327125
90G-protein coupled receptor internalization (GO:0002031)2.81148535
91replicative senescence (GO:0090399)2.81094112
92reproduction (GO:0000003)2.80935398
93microtubule-based process (GO:0007017)2.80896741
94facial nerve structural organization (GO:0021612)2.79067842
95sulfate transport (GO:0008272)2.77318582
96organelle assembly (GO:0070925)2.75955605
97regulation of smoothened signaling pathway (GO:0008589)2.73687025
98regulation of collateral sprouting (GO:0048670)2.71369971
99startle response (GO:0001964)2.69670938
100sensory perception of chemical stimulus (GO:0007606)2.68310994
101pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.68050181
102apical protein localization (GO:0045176)2.68013722
103ganglion development (GO:0061548)2.67876168
104negative regulation of execution phase of apoptosis (GO:1900118)2.66549511
105regulation of meiosis I (GO:0060631)2.65590025
106retinal cone cell development (GO:0046549)2.64845417
107regulation of development, heterochronic (GO:0040034)2.64525205
108heart looping (GO:0001947)2.63971770
109cell-cell recognition (GO:0009988)2.63807716
110negative regulation of humoral immune response (GO:0002921)2.63000110
111male sex determination (GO:0030238)2.62188362
112microtubule severing (GO:0051013)2.60559522
113regulation of keratinocyte proliferation (GO:0010837)2.60450616
114negative regulation of DNA-dependent DNA replication (GO:2000104)2.60336270
115cornea development in camera-type eye (GO:0061303)2.59878425
116positive regulation of meiosis (GO:0045836)2.58676191
117regulation of interleukin-13 production (GO:0032656)2.58638647
118cell projection assembly (GO:0030031)2.58084832
119inner ear receptor stereocilium organization (GO:0060122)2.57762036
120tolerance induction (GO:0002507)2.56594133
121nucleotide phosphorylation (GO:0046939)2.55553789
122retinal rod cell development (GO:0046548)2.55039440
123spinal cord motor neuron differentiation (GO:0021522)2.54888122
124response to X-ray (GO:0010165)2.54809155
125meiotic cell cycle (GO:0051321)2.54765863
126centriole replication (GO:0007099)2.54419136
127glutathione derivative metabolic process (GO:1901685)2.54102720
128glutathione derivative biosynthetic process (GO:1901687)2.54102720
129protein K6-linked ubiquitination (GO:0085020)2.52917843
130negative regulation of homotypic cell-cell adhesion (GO:0034111)2.52584369
131adenosine metabolic process (GO:0046085)2.51574655
132spermatid development (GO:0007286)2.51224372
133cranial nerve structural organization (GO:0021604)2.50728377
134positive regulation of meiotic cell cycle (GO:0051446)2.50702827
135positive regulation of male gonad development (GO:2000020)2.50685665
136fertilization (GO:0009566)2.49964279
137left/right pattern formation (GO:0060972)2.47935052
138regulation of chromatin binding (GO:0035561)2.47647915
139smoothened signaling pathway (GO:0007224)2.47001856
140retinol metabolic process (GO:0042572)2.46636632
141meiotic chromosome segregation (GO:0045132)2.46229594
142presynaptic membrane assembly (GO:0097105)2.43917576
143retina layer formation (GO:0010842)2.43034593
144embryonic heart tube morphogenesis (GO:0003143)2.42927633
145keratinocyte development (GO:0003334)2.42835159
146mesenchymal cell differentiation involved in kidney development (GO:0072161)2.42464321
147mesenchymal cell differentiation involved in renal system development (GO:2001012)2.42464321
148pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.42210481
149dentate gyrus development (GO:0021542)2.41453026
150drug catabolic process (GO:0042737)2.40670609
151regulation of non-canonical Wnt signaling pathway (GO:2000050)2.40392081
152auditory receptor cell stereocilium organization (GO:0060088)2.39400018
153primary alcohol metabolic process (GO:0034308)2.37557875
154eye photoreceptor cell differentiation (GO:0001754)2.33243300
155photoreceptor cell differentiation (GO:0046530)2.33243300
156regulation of germinal center formation (GO:0002634)2.30681996
157brain morphogenesis (GO:0048854)2.24997162
158otic vesicle formation (GO:0030916)2.24637286
159embryonic camera-type eye development (GO:0031076)2.22351587
160excretion (GO:0007588)2.21582398
161establishment of nucleus localization (GO:0040023)2.20798473
162asymmetric protein localization (GO:0008105)2.18953103
163phosphatidylcholine biosynthetic process (GO:0006656)2.15096955
164intra-S DNA damage checkpoint (GO:0031573)2.15082098
165O-glycan processing (GO:0016266)2.14036768
166embryonic body morphogenesis (GO:0010172)2.13880567
167regulation of microtubule depolymerization (GO:0031114)2.13416667

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.22955153
2GBX2_23144817_ChIP-Seq_PC3_Human3.21330656
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.20549164
4PCGF2_27294783_Chip-Seq_ESCs_Mouse2.98880182
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.82352302
6FLI1_27457419_Chip-Seq_LIVER_Mouse2.79266797
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.71433359
8SUZ12_27294783_Chip-Seq_NPCs_Mouse2.54189593
9PCGF2_27294783_Chip-Seq_NPCs_Mouse2.53367671
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.46991727
11NFE2_27457419_Chip-Seq_LIVER_Mouse2.44737445
12GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.44236652
13FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human2.33717272
14BMI1_23680149_ChIP-Seq_NPCS_Mouse2.25028087
15VDR_22108803_ChIP-Seq_LS180_Human2.18195482
16ZNF274_21170338_ChIP-Seq_K562_Hela2.04132616
17EZH2_27294783_Chip-Seq_NPCs_Mouse2.01210204
18TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse2.00151535
19EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.99672596
20POU3F2_20337985_ChIP-ChIP_501MEL_Human1.96254315
21NANOG_18555785_Chip-Seq_ESCs_Mouse1.94963826
22RNF2_27304074_Chip-Seq_NSC_Mouse1.94722567
23TAF15_26573619_Chip-Seq_HEK293_Human1.93002600
24IGF1R_20145208_ChIP-Seq_DFB_Human1.92862630
25CBX2_27304074_Chip-Seq_ESCs_Mouse1.91731064
26P53_22387025_ChIP-Seq_ESCs_Mouse1.87789892
27SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.87415373
28STAT3_18555785_Chip-Seq_ESCs_Mouse1.86756377
29SUZ12_18555785_Chip-Seq_ESCs_Mouse1.85021105
30EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.80736418
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.79471343
32CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.78206213
33SMAD_19615063_ChIP-ChIP_OVARY_Human1.78034010
34E2F1_18555785_Chip-Seq_ESCs_Mouse1.77911068
35P300_19829295_ChIP-Seq_ESCs_Human1.75213280
36CMYC_18555785_Chip-Seq_ESCs_Mouse1.71289508
37OCT4_18555785_Chip-Seq_ESCs_Mouse1.70598225
38HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.70435526
39NMYC_18555785_Chip-Seq_ESCs_Mouse1.70229601
40CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.68394737
41P300_18555785_Chip-Seq_ESCs_Mouse1.68195107
42SOX2_18555785_Chip-Seq_ESCs_Mouse1.68019066
43RUNX1_27457419_Chip-Seq_LIVER_Mouse1.67443190
44ZFX_18555785_Chip-Seq_ESCs_Mouse1.66564372
45PU1_27457419_Chip-Seq_LIVER_Mouse1.55916443
46AHR_22903824_ChIP-Seq_MCF-7_Human1.55533647
47PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54953151
48KLF4_18555785_Chip-Seq_ESCs_Mouse1.53706867
49FOXM1_26456572_ChIP-Seq_MCF-7_Human1.52261988
50ESRRB_18555785_Chip-Seq_ESCs_Mouse1.51958803
51CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.51917804
52SMAD4_21799915_ChIP-Seq_A2780_Human1.51081941
53POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.50710256
54TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.50710256
55NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.50103627
56TAL1_26923725_Chip-Seq_HPCs_Mouse1.49006471
57CRX_20693478_ChIP-Seq_RETINA_Mouse1.48467017
58EED_16625203_ChIP-ChIP_MESCs_Mouse1.48072018
59FUS_26573619_Chip-Seq_HEK293_Human1.48003277
60OCT4_21477851_ChIP-Seq_ESCs_Mouse1.47411679
61CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.47197049
62PIAS1_25552417_ChIP-Seq_VCAP_Human1.46702628
63CTBP2_25329375_ChIP-Seq_LNCAP_Human1.45929706
64MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.45614233
65CTCF_18555785_Chip-Seq_ESCs_Mouse1.43528869
66SALL1_21062744_ChIP-ChIP_HESCs_Human1.41767868
67BCAT_22108803_ChIP-Seq_LS180_Human1.41580236
68TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.39347639
69SMAD1_18555785_Chip-Seq_ESCs_Mouse1.38860561
70TCF4_22108803_ChIP-Seq_LS180_Human1.37096424
71CTBP1_25329375_ChIP-Seq_LNCAP_Human1.33820202
72SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.32574942
73CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.31817068
74MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.31791880
75ER_23166858_ChIP-Seq_MCF-7_Human1.31502602
76AR_21572438_ChIP-Seq_LNCaP_Human1.31319003
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.30502534
78AR_25329375_ChIP-Seq_VCAP_Human1.29655631
79RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.29257927
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.27710701
81TCF4_23295773_ChIP-Seq_U87_Human1.27302579
82ETV1_20927104_ChIP-Seq_GIST48_Human1.26186781
83SMAD3_21741376_ChIP-Seq_EPCs_Human1.25790075
84STAT3_23295773_ChIP-Seq_U87_Human1.25644916
85KDM2B_26808549_Chip-Seq_REH_Human1.25619646
86LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.25369279
87SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.24296171
88ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.23693290
89KAP1_22055183_ChIP-Seq_ESCs_Mouse1.23472965
90ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23401941
91TP63_19390658_ChIP-ChIP_HaCaT_Human1.22849911
92SMAD4_21741376_ChIP-Seq_EPCs_Human1.21827481
93PHF8_20622853_ChIP-Seq_HELA_Human1.21778779
94EWS_26573619_Chip-Seq_HEK293_Human1.21462764
95CBP_20019798_ChIP-Seq_JUKART_Human1.20013265
96IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20013265
97EZH2_27304074_Chip-Seq_ESCs_Mouse1.19647187
98TOP2B_26459242_ChIP-Seq_MCF-7_Human1.19366670
99CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.18507288
100FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.18324557
101REST_21632747_ChIP-Seq_MESCs_Mouse1.18318533
102PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.17651046
103NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17080696
104DROSHA_22980978_ChIP-Seq_HELA_Human1.16632074
105TBL1_22424771_ChIP-Seq_293T_Human1.16508909
106JARID2_20064375_ChIP-Seq_MESCs_Mouse1.15973881
107KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15112375
108SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.13799307
109TP53_16413492_ChIP-PET_HCT116_Human1.13776161
110TP53_18474530_ChIP-ChIP_U2OS_Human1.13398037
111FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.11910351
112RUNX2_22187159_ChIP-Seq_PCA_Human1.11033430
113ESR1_20079471_ChIP-ChIP_T-47D_Human1.10241416
114SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.10111352
115NFYB_21822215_ChIP-Seq_K562_Human1.10032424
116ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09403034
117HNFA_21074721_ChIP-Seq_CACO-2_Human1.09039621
118MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09027218
119TP63_23658742_ChIP-Seq_EP156T_Human1.08971621
120SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08240239
121ARNT_22903824_ChIP-Seq_MCF-7_Human1.08140260
122OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07954248
123WDR5_24793694_ChIP-Seq_LNCAP_Human1.07761172
124TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07379340
125NFYA_21822215_ChIP-Seq_K562_Human1.07149526
126CDX2_19796622_ChIP-Seq_MESCs_Mouse1.07119690
127SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.06877028
128UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06365556
129EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.05869963
130CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.05838456
131FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05799533
132FOXA1_25329375_ChIP-Seq_VCAP_Human1.05799533
133SUZ12_27294783_Chip-Seq_ESCs_Mouse1.05613593
134RNF2_27304074_Chip-Seq_ESCs_Mouse1.04640104
135EZH2_27294783_Chip-Seq_ESCs_Mouse1.04071196
136AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.03889415
137JARID2_20075857_ChIP-Seq_MESCs_Mouse1.03824342
138PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03378059
139P53_22127205_ChIP-Seq_FIBROBLAST_Human1.02906347
140POU5F1_16153702_ChIP-ChIP_HESCs_Human1.02882552
141GATA1_26923725_Chip-Seq_HPCs_Mouse1.02412683
142E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.02333196
143SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.02125799
144STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.02076151
145TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.01534972
146NANOG_19829295_ChIP-Seq_ESCs_Human1.01259865
147SOX2_19829295_ChIP-Seq_ESCs_Human1.01259865
148SMRT_27268052_Chip-Seq_Bcells_Human1.01180525
149CBX2_22325352_ChIP-Seq_293T-Rex_Human0.99810488
150KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99761702
151SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.99166151

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction4.32503150
2MP0003136_yellow_coat_color4.16001345
3MP0001188_hyperpigmentation3.90391775
4MP0008875_abnormal_xenobiotic_pharmacok3.78472562
5MP0006292_abnormal_olfactory_placode3.15854661
6MP0005410_abnormal_fertilization3.10169441
7MP0005646_abnormal_pituitary_gland3.02534225
8MP0000566_synostosis2.92934951
9MP0002102_abnormal_ear_morphology2.79445185
10MP0005645_abnormal_hypothalamus_physiol2.66653045
11MP0004381_abnormal_hair_follicle2.64494317
12MP0004043_abnormal_pH_regulation2.47952525
13MP0009780_abnormal_chondrocyte_physiolo2.44828956
14MP0008058_abnormal_DNA_repair2.42551479
15MP0008789_abnormal_olfactory_epithelium2.30302996
16MP0002653_abnormal_ependyma_morphology2.25868932
17MP0003787_abnormal_imprinting2.13864882
18MP0002282_abnormal_trachea_morphology2.12393324
19MP0000015_abnormal_ear_pigmentation2.11801740
20MP0005394_taste/olfaction_phenotype2.05612299
21MP0005499_abnormal_olfactory_system2.05612299
22MP0010030_abnormal_orbit_morphology2.05388236
23MP0000383_abnormal_hair_follicle1.86637442
24MP0003941_abnormal_skin_development1.82255544
25MP0005551_abnormal_eye_electrophysiolog1.80321878
26MP0001485_abnormal_pinna_reflex1.66558635
27MP0003698_abnormal_male_reproductive1.64424065
28MP0003122_maternal_imprinting1.57389529
29MP0002132_abnormal_respiratory_system1.56234343
30MP0001986_abnormal_taste_sensitivity1.55579050
31MP0005171_absent_coat_pigmentation1.54172989
32MP0002277_abnormal_respiratory_mucosa1.52607364
33MP0002638_abnormal_pupillary_reflex1.52486816
34MP0003011_delayed_dark_adaptation1.51468795
35MP0008877_abnormal_DNA_methylation1.47051602
36MP0001929_abnormal_gametogenesis1.43715224
37MP0003283_abnormal_digestive_organ1.43696237
38MP0000026_abnormal_inner_ear1.41898084
39MP0005409_darkened_coat_color1.41270450
40MP0000372_irregular_coat_pigmentation1.39186892
41MP0005248_abnormal_Harderian_gland1.38909776
42MP0002009_preneoplasia1.37038810
43MP0000631_abnormal_neuroendocrine_gland1.36171569
44MP0005253_abnormal_eye_physiology1.35393894
45MP0001486_abnormal_startle_reflex1.35006927
46MP0004782_abnormal_surfactant_physiolog1.34151810
47MP0005075_abnormal_melanosome_morpholog1.30390609
48MP0009697_abnormal_copulation1.30264293
49MP0002210_abnormal_sex_determination1.27650788
50MP0000427_abnormal_hair_cycle1.27298430
51MP0000678_abnormal_parathyroid_gland1.24480295
52MP0005379_endocrine/exocrine_gland_phen1.23488491
53MP0000049_abnormal_middle_ear1.22611267
54MP0002249_abnormal_larynx_morphology1.21323807
55MP0002938_white_spotting1.21098565
56MP0003880_abnormal_central_pattern1.20998194
57MP0005174_abnormal_tail_pigmentation1.20940487
58MP0001346_abnormal_lacrimal_gland1.20797023
59MP0000569_abnormal_digit_pigmentation1.20760002
60MP0003786_premature_aging1.16328329
61MP0002928_abnormal_bile_duct1.15574981
62MP0002909_abnormal_adrenal_gland1.14390523
63MP0004742_abnormal_vestibular_system1.13766531
64MP0008995_early_reproductive_senescence1.12274739
65MP0002233_abnormal_nose_morphology1.12120269
66MP0000579_abnormal_nail_morphology1.10947316
67MP0006072_abnormal_retinal_apoptosis1.10587909
68MP0002168_other_aberrant_phenotype1.05820044
69MP0001299_abnormal_eye_distance/1.05753963
70MP0009379_abnormal_foot_pigmentation1.03588309
71MP0002752_abnormal_somatic_nervous1.02675894
72MP0002095_abnormal_skin_pigmentation1.02447056
73MP0002557_abnormal_social/conspecific_i1.00756258
74MP0005377_hearing/vestibular/ear_phenot1.00576108
75MP0003878_abnormal_ear_physiology1.00576108
76MP0010386_abnormal_urinary_bladder1.00549326
77MP0000955_abnormal_spinal_cord1.00311036
78MP0009745_abnormal_behavioral_response1.00066744
79MP0008260_abnormal_autophagy0.99721863
80MP0001963_abnormal_hearing_physiology0.99611566
81MP0004133_heterotaxia0.97706032
82MP0005195_abnormal_posterior_eye0.96845957
83MP0002572_abnormal_emotion/affect_behav0.96665653
84MP0004885_abnormal_endolymph0.96325537
85MP0001529_abnormal_vocalization0.96237859
86MP0001324_abnormal_eye_pigmentation0.94996650
87MP0002876_abnormal_thyroid_physiology0.94816352
88MP0001502_abnormal_circadian_rhythm0.94673933
89MP0001765_abnormal_ion_homeostasis0.94421109
90MP0002160_abnormal_reproductive_system0.94073983
91MP0006276_abnormal_autonomic_nervous0.93047879
92MP0002098_abnormal_vibrissa_morphology0.92980056
93MP0003718_maternal_effect0.92672180
94MP0002735_abnormal_chemical_nociception0.90428956
95MP0009250_abnormal_appendicular_skeleto0.90271289
96MP0002822_catalepsy0.89849255
97MP0005391_vision/eye_phenotype0.89631184
98MP0002177_abnormal_outer_ear0.89019579
99MP0000653_abnormal_sex_gland0.87824742
100MP0003195_calcinosis0.87247946
101MP0000778_abnormal_nervous_system0.86984708
102MP0003938_abnormal_ear_development0.86946589
103MP0004019_abnormal_vitamin_homeostasis0.86491171
104MP0001970_abnormal_pain_threshold0.86339723
105MP0003861_abnormal_nervous_system0.85782610
106MP0002163_abnormal_gland_morphology0.85439409
107MP0003119_abnormal_digestive_system0.85405818
108MP0001119_abnormal_female_reproductive0.85246299
109MP0001293_anophthalmia0.84638338
110MP0001145_abnormal_male_reproductive0.83535897
111MP0001968_abnormal_touch/_nociception0.83440513
112MP0002116_abnormal_craniofacial_bone0.83375381
113MP0002272_abnormal_nervous_system0.82980783
114MP0003937_abnormal_limbs/digits/tail_de0.81288593
115MP0008057_abnormal_DNA_replication0.80064998
116MP0004142_abnormal_muscle_tone0.79983717
117MP0001270_distended_abdomen0.79225428
118MP0005451_abnormal_body_composition0.79153091
119MP0005389_reproductive_system_phenotype0.78479540
120MP0002067_abnormal_sensory_capabilities0.77851751
121MP0002184_abnormal_innervation0.77450247
122MP0005083_abnormal_biliary_tract0.76794804
123MP0002161_abnormal_fertility/fecundity0.76580002
124MP0005636_abnormal_mineral_homeostasis0.76479072
125MP0009046_muscle_twitch0.75931957
126MP0002152_abnormal_brain_morphology0.75010665
127MP0002882_abnormal_neuron_morphology0.73993799
128MP0000470_abnormal_stomach_morphology0.73790658
129MP0003890_abnormal_embryonic-extraembry0.73455767
130MP0005623_abnormal_meninges_morphology0.73175211
131MP0001286_abnormal_eye_development0.72852526
132MP0000538_abnormal_urinary_bladder0.72617341
133MP0001944_abnormal_pancreas_morphology0.72492501
134MP0002064_seizures0.72103532
135MP0005395_other_phenotype0.71984302
136MP0000762_abnormal_tongue_morphology0.71564431
137MP0010678_abnormal_skin_adnexa0.70927147
138MP0002734_abnormal_mechanical_nocicepti0.70722286
139MP0003755_abnormal_palate_morphology0.70611993
140MP0002751_abnormal_autonomic_nervous0.70293437
141MP0002229_neurodegeneration0.68417233
142MP0002736_abnormal_nociception_after0.68226939
143MP0002063_abnormal_learning/memory/cond0.67608989
144MP0004859_abnormal_synaptic_plasticity0.66640108
145MP0005187_abnormal_penis_morphology0.65895101

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)7.84560587
2Abnormal ciliary motility (HP:0012262)7.45690496
3Abnormal respiratory motile cilium physiology (HP:0012261)7.26210699
4Dynein arm defect of respiratory motile cilia (HP:0012255)6.27004609
5Absent/shortened dynein arms (HP:0200106)6.27004609
6Abnormal respiratory motile cilium morphology (HP:0005938)6.13046083
7Abnormal respiratory epithelium morphology (HP:0012253)6.13046083
8Nasal polyposis (HP:0100582)5.33167561
9Rhinitis (HP:0012384)5.26472171
10Chromosomal breakage induced by crosslinking agents (HP:0003221)4.41552354
11Abnormality of the nasal mucosa (HP:0000433)4.27882821
12Chromsome breakage (HP:0040012)3.86906466
13Chronic hepatic failure (HP:0100626)3.72846877
14Bronchitis (HP:0012387)3.59339925
15True hermaphroditism (HP:0010459)3.58338047
16Nephronophthisis (HP:0000090)3.51193623
17Pancreatic fibrosis (HP:0100732)3.32615901
18Tubulointerstitial nephritis (HP:0001970)3.26387483
19Bronchiectasis (HP:0002110)3.14330905
20Recurrent otitis media (HP:0000403)3.13038559
21Febrile seizures (HP:0002373)3.08293256
22Chronic bronchitis (HP:0004469)3.06580785
23Abnormality of the renal medulla (HP:0100957)2.99675806
24Male infertility (HP:0003251)2.98497567
25Medial flaring of the eyebrow (HP:0010747)2.98128358
26Molar tooth sign on MRI (HP:0002419)2.97264702
27Abnormality of midbrain morphology (HP:0002418)2.97264702
28Congenital stationary night blindness (HP:0007642)2.95841412
29Chronic otitis media (HP:0000389)2.73229040
30Recurrent sinusitis (HP:0011108)2.66970889
31Median cleft lip (HP:0000161)2.65533472
32Congenital hepatic fibrosis (HP:0002612)2.62183894
33Prostate neoplasm (HP:0100787)2.60652759
34Congenital primary aphakia (HP:0007707)2.57839477
35Pancreatic cysts (HP:0001737)2.55546669
36Upper limb muscle weakness (HP:0003484)2.54570985
37Gait imbalance (HP:0002141)2.51477218
38Nephrogenic diabetes insipidus (HP:0009806)2.50595642
39Postaxial foot polydactyly (HP:0001830)2.50450800
40Anencephaly (HP:0002323)2.49839304
41Septo-optic dysplasia (HP:0100842)2.43694939
42Hyperactive renin-angiotensin system (HP:0000841)2.40617014
43Sclerocornea (HP:0000647)2.30040580
44Renal cortical cysts (HP:0000803)2.27163162
45Poor coordination (HP:0002370)2.26677889
46Preaxial hand polydactyly (HP:0001177)2.26577395
47Abnormality of the renal cortex (HP:0011035)2.26483281
48Tubular atrophy (HP:0000092)2.24674851
49Decreased central vision (HP:0007663)2.23723715
50Bifid tongue (HP:0010297)2.19453701
51Abnormality of molar (HP:0011077)2.17349587
52Abnormality of molar morphology (HP:0011070)2.17349587
53Male pseudohermaphroditism (HP:0000037)2.17016328
54Aplasia/Hypoplasia of the uvula (HP:0010293)2.13847402
55Aplasia/Hypoplasia of the lens (HP:0008063)2.11613012
56Abnormal hair whorl (HP:0010721)2.09159184
57Genital tract atresia (HP:0001827)2.06918548
58Abnormality of permanent molar morphology (HP:0011071)2.05959082
59Abnormality of the dental root (HP:0006486)2.05959082
60Taurodontia (HP:0000679)2.05959082
61Congenital sensorineural hearing impairment (HP:0008527)2.05434696
62Postaxial hand polydactyly (HP:0001162)2.03890530
63Vaginal atresia (HP:0000148)1.99462954
64Optic nerve hypoplasia (HP:0000609)1.99039478
65Facial cleft (HP:0002006)1.98734034
66Ectopic kidney (HP:0000086)1.98452330
67Abnormality of the preputium (HP:0100587)1.95760306
68Furrowed tongue (HP:0000221)1.95429237
69Nephroblastoma (Wilms tumor) (HP:0002667)1.94565441
70Duplicated collecting system (HP:0000081)1.94016493
71Cystic liver disease (HP:0006706)1.93755779
72Abnormality of the dental pulp (HP:0006479)1.93725495
73Hypothermia (HP:0002045)1.92831979
74Abnormality of the fovea (HP:0000493)1.92709674
75Abnormality of the renal collecting system (HP:0004742)1.91798589
76White forelock (HP:0002211)1.90836603
77Abnormal sex determination (HP:0012244)1.90083840
78Sex reversal (HP:0012245)1.90083840
79Meckel diverticulum (HP:0002245)1.90052974
80Aplasia/Hypoplasia of the tongue (HP:0010295)1.88890394
81Aganglionic megacolon (HP:0002251)1.87417685
82Aplasia/Hypoplasia of the fovea (HP:0008060)1.86041353
83Hypoplasia of the fovea (HP:0007750)1.86041353
84Abnormality of incisor morphology (HP:0011063)1.85193134
85Bell-shaped thorax (HP:0001591)1.85065433
86Oculomotor apraxia (HP:0000657)1.84839313
87Embryonal renal neoplasm (HP:0011794)1.84475347
88Aplasia/Hypoplasia of the spleen (HP:0010451)1.82620423
89Abnormality of the ileum (HP:0001549)1.82529343
90Tubulointerstitial abnormality (HP:0001969)1.82196785
91Stage 5 chronic kidney disease (HP:0003774)1.82076194
92Atelectasis (HP:0100750)1.80443839
93Asplenia (HP:0001746)1.80224468
94Decreased circulating renin level (HP:0003351)1.80065869
95Abnormal drinking behavior (HP:0030082)1.79840478
96Polydipsia (HP:0001959)1.79840478
97Bony spicule pigmentary retinopathy (HP:0007737)1.79678114
98Occipital encephalocele (HP:0002085)1.79666111
99Retinal dysplasia (HP:0007973)1.79209417
100Abnormality of DNA repair (HP:0003254)1.78493696
101Abnormal rod and cone electroretinograms (HP:0008323)1.77715995
102Patchy hypopigmentation of hair (HP:0011365)1.76515683
103Onycholysis (HP:0001806)1.73617602
104Clubbing of toes (HP:0100760)1.73114305
105Astigmatism (HP:0000483)1.72151485
106Absent rod-and cone-mediated responses on ERG (HP:0007688)1.71992860
107Absent eyebrow (HP:0002223)1.70383877
108Chronic sinusitis (HP:0011109)1.69332062
109Nephropathy (HP:0000112)1.69297643
110Attenuation of retinal blood vessels (HP:0007843)1.69235639
111Infertility (HP:0000789)1.69070342
112Oligohydramnios (HP:0001562)1.68791173
113Abnormality of chromosome stability (HP:0003220)1.66054993
114Abnormal biliary tract physiology (HP:0012439)1.64279473
115Bile duct proliferation (HP:0001408)1.64279473
116Alveolar cell carcinoma (HP:0006519)1.62831767
117Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.62327555
118Impulsivity (HP:0100710)1.56794801
119Renal dysplasia (HP:0000110)1.54828586
120Renal salt wasting (HP:0000127)1.54051994
121Recurrent bronchitis (HP:0002837)1.53609678
122Aplasia cutis congenita (HP:0001057)1.53407954
123Supernumerary spleens (HP:0009799)1.50711545
124Hyperaldosteronism (HP:0000859)1.43248958
125Tubulointerstitial fibrosis (HP:0005576)1.39973025
126Hyperkalemia (HP:0002153)1.37307431
127Retinitis pigmentosa (HP:0000510)1.36119044
128Narrow forehead (HP:0000341)1.35007405
129Bifid scrotum (HP:0000048)1.34248314
130Absent frontal sinuses (HP:0002688)1.33522589
131Abnormality of renin-angiotensin system (HP:0000847)1.31345106
132Anophthalmia (HP:0000528)1.31294649
133Broad foot (HP:0001769)1.30685769
134Multicystic kidney dysplasia (HP:0000003)1.27338321
135Specific learning disability (HP:0001328)1.27136019
136Prominent nasal bridge (HP:0000426)1.24745996
137Cone-rod dystrophy (HP:0000548)1.24713673
138Polyuria (HP:0000103)1.23978593
139Short thorax (HP:0010306)1.20983302
140Holoprosencephaly (HP:0001360)1.18348270
141Abnormality of renal excretion (HP:0011036)1.14876164
142Abnormality of chloride homeostasis (HP:0011422)1.14378524
143Abnormality of abdominal situs (HP:0011620)1.13991085
144Abdominal situs inversus (HP:0003363)1.13991085
145Highly arched eyebrow (HP:0002553)1.13607731

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.25997429
2PNCK3.65520382
3MST43.51579734
4ZAK2.56210660
5IRAK32.53335573
6GRK12.46885292
7WNK32.27072801
8MAPK152.25972193
9MKNK22.23458563
10AKT32.21690990
11PRPF4B2.19987846
12INSRR2.10836231
13EIF2AK22.04097321
14IRAK42.01581725
15MAP3K41.95556340
16STK161.82513516
17STK38L1.82308046
18IRAK11.82121359
19TNIK1.79850987
20SIK31.74398066
21TXK1.74036200
22PTK2B1.70756866
23SGK21.70047875
24CDK31.66498699
25MAP2K71.65806565
26NEK61.59480974
27MAPKAPK31.53835472
28MUSK1.53152956
29YES11.52477877
30EPHA41.51551635
31SRPK11.50194886
32NME11.46349897
33BRSK21.40966656
34MAP3K141.39216450
35MKNK11.38221979
36NLK1.34203059
37MAP4K21.33315172
38MAPK131.32128949
39IRAK21.31673123
40FGFR21.28816924
41ERBB31.28467605
42BMPR21.26914325
43MAP3K21.25650803
44NUAK11.23158032
45WEE11.20428848
46SGK4941.18945612
47SGK2231.18945612
48BMPR1B1.18452943
49NTRK21.12720318
50TNK21.09805759
51WNK41.03204009
52TSSK61.02203391
53CHEK21.02075925
54TTK0.99049794
55ADRBK20.97331482
56PLK40.94875275
57VRK10.94719018
58PKN10.91623512
59BLK0.88119817
60EPHB20.87447520
61FRK0.86999471
62TRPM70.85001941
63ERBB20.83086300
64SGK30.82858749
65CCNB10.81049243
66TEC0.80510356
67STK390.79227958
68PINK10.78150821
69MARK10.77381166
70ACVR1B0.77162720
71OXSR10.76957197
72CDK190.73222957
73EEF2K0.73015874
74GRK70.72301335
75MAP2K40.72241509
76STK240.72096389
77TIE10.68370946
78DYRK30.67102571
79MAP3K70.66606062
80PRKCE0.66010394
81CDK120.63317787
82CAMKK10.63221887
83CAMK1G0.62756947
84PRKAA20.62511501
85EPHA30.62328231
86PRKCI0.62050323
87LATS10.60669686
88ATR0.60620694
89PASK0.60508813
90DYRK1A0.60122239
91DYRK20.59787723
92PRKD30.59717955
93PIK3CG0.59462651
94EPHA20.57019685
95PRKCG0.56350239
96TRIM280.56281310
97ERBB40.53864514
98CAMKK20.53471301
99LRRK20.52529679
100UHMK10.51936769
101CAMK1D0.50423594
102BRAF0.50387479
103ADRBK10.49996277
104CDK80.49754260
105CHUK0.49530972
106CLK10.49410841
107PLK30.49100613
108TGFBR10.48220894
109RPS6KA50.48092330
110MAP3K120.47709386
111BRD40.47687083
112NTRK30.47177873
113CAMK2A0.45247969
114ATM0.44889732
115PDK30.44044422
116PDK40.44044422
117CDK90.43443144
118PRKCQ0.43012759
119PAK30.42902309
120PLK10.42230162
121EPHB10.41971148
122STK110.41431058
123PRKACA0.40936059
124PRKG10.40201189
125MAPK70.40124142
126STK30.39738520
127CAMK2B0.39303619
128BCR0.39125232
129MELK0.38989940
130SGK10.38745348
131PDK20.38647031
132PLK20.37983910
133IKBKE0.37896324
134CSNK1G20.37473945
135SIK20.37254242
136MARK20.35370805
137CAMK2D0.35114414
138PRKCZ0.34825644
139DYRK1B0.34587482
140TLK10.34295198
141IKBKB0.34098791
142STK380.34091315
143CAMK40.33829867
144MAPKAPK50.33602814
145FER0.32170069
146ROCK20.28447238
147MET0.28374242
148CSK0.27930500
149CSNK1G10.27089562
150MINK10.26809895

Predicted pathways (KEGG)

RankGene SetZ-score
1Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009803.98675555
2Chemical carcinogenesis_Homo sapiens_hsa052043.41864181
3Phototransduction_Homo sapiens_hsa047443.32464188
4Histidine metabolism_Homo sapiens_hsa003403.31114351
5Fanconi anemia pathway_Homo sapiens_hsa034603.24031671
6Phenylalanine metabolism_Homo sapiens_hsa003603.14853202
7Olfactory transduction_Homo sapiens_hsa047403.04221973
8Huntingtons disease_Homo sapiens_hsa050163.01044692
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.76119943
10beta-Alanine metabolism_Homo sapiens_hsa004102.71293648
11Tyrosine metabolism_Homo sapiens_hsa003502.50047723
12Sphingolipid metabolism_Homo sapiens_hsa006002.32400819
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.96663601
14Caffeine metabolism_Homo sapiens_hsa002321.93521188
15Homologous recombination_Homo sapiens_hsa034401.89894347
16Non-homologous end-joining_Homo sapiens_hsa034501.89533361
17Basal transcription factors_Homo sapiens_hsa030221.88063944
18Nicotine addiction_Homo sapiens_hsa050331.87488239
19Taste transduction_Homo sapiens_hsa047421.86120860
20Glutathione metabolism_Homo sapiens_hsa004801.80164953
21Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.78700588
22Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.77742941
23Butanoate metabolism_Homo sapiens_hsa006501.74645751
24Arachidonic acid metabolism_Homo sapiens_hsa005901.64704197
25Morphine addiction_Homo sapiens_hsa050321.60021972
26Other glycan degradation_Homo sapiens_hsa005111.49320725
27Vitamin B6 metabolism_Homo sapiens_hsa007501.44644637
28Linoleic acid metabolism_Homo sapiens_hsa005911.38606004
29Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.37198664
30Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.37041561
31Vitamin digestion and absorption_Homo sapiens_hsa049771.36802171
32Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.34189942
33Ether lipid metabolism_Homo sapiens_hsa005651.33474480
34Ovarian steroidogenesis_Homo sapiens_hsa049131.32597433
35Peroxisome_Homo sapiens_hsa041461.29381706
36Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.29055291
37alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.27867545
38Nitrogen metabolism_Homo sapiens_hsa009101.27462353
39Serotonergic synapse_Homo sapiens_hsa047261.24427331
40Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.23896377
41NF-kappa B signaling pathway_Homo sapiens_hsa040641.23578670
42Insulin secretion_Homo sapiens_hsa049111.23001285
43Maturity onset diabetes of the young_Homo sapiens_hsa049501.17522175
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.16284111
45Tight junction_Homo sapiens_hsa045301.14996212
46Basal cell carcinoma_Homo sapiens_hsa052171.13443089
47Glycosaminoglycan degradation_Homo sapiens_hsa005311.12696973
48Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.12183042
49Fatty acid degradation_Homo sapiens_hsa000711.11978791
50Purine metabolism_Homo sapiens_hsa002301.10641368
51Oxidative phosphorylation_Homo sapiens_hsa001901.07942122
52ABC transporters_Homo sapiens_hsa020101.06608420
53Primary bile acid biosynthesis_Homo sapiens_hsa001201.06333911
54Retinol metabolism_Homo sapiens_hsa008301.05794027
55SNARE interactions in vesicular transport_Homo sapiens_hsa041301.05612036
56Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.04840100
57Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.04788120
58Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.02746158
59Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.01458570
60Circadian rhythm_Homo sapiens_hsa047101.01421596
61Intestinal immune network for IgA production_Homo sapiens_hsa046720.97099988
62Protein export_Homo sapiens_hsa030600.97043673
63Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.96723435
64Salivary secretion_Homo sapiens_hsa049700.96449219
65Propanoate metabolism_Homo sapiens_hsa006400.96019430
66Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.94749853
67Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.94385575
68Autoimmune thyroid disease_Homo sapiens_hsa053200.93956557
69Rheumatoid arthritis_Homo sapiens_hsa053230.93797095
70Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.93167486
71Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.92868954
72Circadian entrainment_Homo sapiens_hsa047130.92342067
73Hematopoietic cell lineage_Homo sapiens_hsa046400.91497043
74Cardiac muscle contraction_Homo sapiens_hsa042600.91010924
75Glutamatergic synapse_Homo sapiens_hsa047240.90668493
76Tryptophan metabolism_Homo sapiens_hsa003800.87132822
77Base excision repair_Homo sapiens_hsa034100.85566622
78Calcium signaling pathway_Homo sapiens_hsa040200.85510860
79Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.83366103
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.83157015
81Nucleotide excision repair_Homo sapiens_hsa034200.82932346
82Collecting duct acid secretion_Homo sapiens_hsa049660.80666818
83Inositol phosphate metabolism_Homo sapiens_hsa005620.79473416
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.78648810
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.77812191
86Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.76869136
87Hippo signaling pathway_Homo sapiens_hsa043900.76132847
88Notch signaling pathway_Homo sapiens_hsa043300.75704539
89Starch and sucrose metabolism_Homo sapiens_hsa005000.75090216
90Mismatch repair_Homo sapiens_hsa034300.74214575
91cAMP signaling pathway_Homo sapiens_hsa040240.70965418
92Graft-versus-host disease_Homo sapiens_hsa053320.70157064
93Wnt signaling pathway_Homo sapiens_hsa043100.69272585
94RNA degradation_Homo sapiens_hsa030180.69242997
95Transcriptional misregulation in cancer_Homo sapiens_hsa052020.69199040
96Amphetamine addiction_Homo sapiens_hsa050310.69157439
97Cell cycle_Homo sapiens_hsa041100.68425296
98Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65786341
99Measles_Homo sapiens_hsa051620.64334988
100Parkinsons disease_Homo sapiens_hsa050120.63997962
101Axon guidance_Homo sapiens_hsa043600.63705725
102Melanoma_Homo sapiens_hsa052180.63656710
103Hedgehog signaling pathway_Homo sapiens_hsa043400.62905918
104GABAergic synapse_Homo sapiens_hsa047270.61728079
105Mineral absorption_Homo sapiens_hsa049780.60752249
106Jak-STAT signaling pathway_Homo sapiens_hsa046300.59742357
107Dorso-ventral axis formation_Homo sapiens_hsa043200.59647386
108Cholinergic synapse_Homo sapiens_hsa047250.57991250
109Metabolic pathways_Homo sapiens_hsa011000.57138270
110Prostate cancer_Homo sapiens_hsa052150.56466269
111Ras signaling pathway_Homo sapiens_hsa040140.56417170
112Primary immunodeficiency_Homo sapiens_hsa053400.55138211
113Alzheimers disease_Homo sapiens_hsa050100.52678708
114Herpes simplex infection_Homo sapiens_hsa051680.52431579
115Glycerolipid metabolism_Homo sapiens_hsa005610.52169242
116Melanogenesis_Homo sapiens_hsa049160.52128621
117Aldosterone synthesis and secretion_Homo sapiens_hsa049250.51891955
118mRNA surveillance pathway_Homo sapiens_hsa030150.51674566
119Allograft rejection_Homo sapiens_hsa053300.51298889
120Steroid biosynthesis_Homo sapiens_hsa001000.50452457
121Regulation of autophagy_Homo sapiens_hsa041400.50191064
122Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.49440332
123Pyrimidine metabolism_Homo sapiens_hsa002400.48790670
124Pancreatic secretion_Homo sapiens_hsa049720.47861517
125Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47552314
126Fatty acid elongation_Homo sapiens_hsa000620.46973762
127Alcoholism_Homo sapiens_hsa050340.45864092
128Malaria_Homo sapiens_hsa051440.44442044
129Arginine and proline metabolism_Homo sapiens_hsa003300.44160392
130Vascular smooth muscle contraction_Homo sapiens_hsa042700.42781178
131cGMP-PKG signaling pathway_Homo sapiens_hsa040220.41982621
132Synaptic vesicle cycle_Homo sapiens_hsa047210.41326037
133Cocaine addiction_Homo sapiens_hsa050300.39054710
134NOD-like receptor signaling pathway_Homo sapiens_hsa046210.37628157
135Bile secretion_Homo sapiens_hsa049760.37436932
136Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.37186639
137HTLV-I infection_Homo sapiens_hsa051660.36534510
138Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.36489359
139Asthma_Homo sapiens_hsa053100.35944041
140Influenza A_Homo sapiens_hsa051640.35167713
141Pathways in cancer_Homo sapiens_hsa052000.34355384
142Adherens junction_Homo sapiens_hsa045200.34278762
143TNF signaling pathway_Homo sapiens_hsa046680.34157808
144Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34089224
145Glycerophospholipid metabolism_Homo sapiens_hsa005640.33587058
146Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33459702
147Dopaminergic synapse_Homo sapiens_hsa047280.33345188
148Fatty acid biosynthesis_Homo sapiens_hsa000610.33195560
149Drug metabolism - other enzymes_Homo sapiens_hsa009830.31149354
150Gastric acid secretion_Homo sapiens_hsa049710.29813287

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