MAD2L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)5.44148389
2protein localization to kinetochore (GO:0034501)5.36554523
3CENP-A containing nucleosome assembly (GO:0034080)5.31145193
4chromatin remodeling at centromere (GO:0031055)5.20235495
5kinetochore organization (GO:0051383)5.13775613
6DNA strand elongation involved in DNA replication (GO:0006271)4.86314635
7attachment of spindle microtubules to kinetochore (GO:0008608)4.85637725
8DNA replication checkpoint (GO:0000076)4.83477290
9protein localization to chromosome, centromeric region (GO:0071459)4.81896997
10telomere maintenance via semi-conservative replication (GO:0032201)4.79903579
11metaphase plate congression (GO:0051310)4.77737938
12DNA replication-independent nucleosome organization (GO:0034724)4.73009618
13DNA replication-independent nucleosome assembly (GO:0006336)4.73009618
14DNA replication initiation (GO:0006270)4.69169587
15kinetochore assembly (GO:0051382)4.68124508
16DNA strand elongation (GO:0022616)4.63677356
17mitotic chromosome condensation (GO:0007076)4.62232559
18DNA ligation (GO:0006266)4.58507850
19telomere maintenance via recombination (GO:0000722)4.49675994
20establishment of chromosome localization (GO:0051303)4.47988176
21mitotic recombination (GO:0006312)4.45690995
22establishment of integrated proviral latency (GO:0075713)4.40239003
23histone exchange (GO:0043486)4.37091234
24DNA unwinding involved in DNA replication (GO:0006268)4.35906131
25meiotic chromosome segregation (GO:0045132)4.35478257
26mitotic nuclear envelope disassembly (GO:0007077)4.20115128
27regulation of spindle organization (GO:0090224)4.16397055
28* mitotic sister chromatid segregation (GO:0000070)4.13409197
29DNA replication-dependent nucleosome assembly (GO:0006335)4.11455369
30DNA replication-dependent nucleosome organization (GO:0034723)4.11455369
31regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.01834762
32nuclear pore organization (GO:0006999)3.97377527
33telomere maintenance via telomere lengthening (GO:0010833)3.89849171
34regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.88410453
35nuclear envelope disassembly (GO:0051081)3.88207393
36membrane disassembly (GO:0030397)3.88207393
37proteasome assembly (GO:0043248)3.86545620
38nuclear pore complex assembly (GO:0051292)3.83615145
39* sister chromatid segregation (GO:0000819)3.83363422
40nucleotide-excision repair, DNA gap filling (GO:0006297)3.76384384
41protein K6-linked ubiquitination (GO:0085020)3.70940181
42* spindle checkpoint (GO:0031577)3.69192988
43protein localization to chromosome (GO:0034502)3.64839510
44regulation of double-strand break repair via homologous recombination (GO:0010569)3.62453655
45chromatin assembly or disassembly (GO:0006333)3.61101671
46positive regulation of chromosome segregation (GO:0051984)3.58093569
47regulation of mitotic spindle organization (GO:0060236)3.58086484
48* chromosome segregation (GO:0007059)3.55232279
49DNA double-strand break processing (GO:0000729)3.53679444
50* regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.51797381
51* regulation of chromosome segregation (GO:0051983)3.51188692
52nucleobase biosynthetic process (GO:0046112)3.45940580
53* negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.45905185
54negative regulation of DNA-dependent DNA replication (GO:2000104)3.44702702
55* spindle assembly checkpoint (GO:0071173)3.42658258
56* negative regulation of chromosome segregation (GO:0051985)3.41870836
57* negative regulation of mitotic sister chromatid segregation (GO:0033048)3.40707752
58* negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.40707752
59* negative regulation of sister chromatid segregation (GO:0033046)3.40707752
60* negative regulation of mitotic sister chromatid separation (GO:2000816)3.40707752
61* regulation of mitotic metaphase/anaphase transition (GO:0030071)3.40659527
62mitotic sister chromatid cohesion (GO:0007064)3.40502627
63* regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.38142345
64* negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.37426326
65ATP-dependent chromatin remodeling (GO:0043044)3.36132683
66IMP biosynthetic process (GO:0006188)3.33765079
67establishment of viral latency (GO:0019043)3.31117227
68* mitotic spindle checkpoint (GO:0071174)3.31019117
69* mitotic spindle assembly checkpoint (GO:0007094)3.30742683
70positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.30342362
71microtubule depolymerization (GO:0007019)3.28307980
72double-strand break repair via nonhomologous end joining (GO:0006303)3.27342911
73non-recombinational repair (GO:0000726)3.27342911
74regulation of centrosome cycle (GO:0046605)3.22774399
75replication fork processing (GO:0031297)3.22385305
76purine nucleobase biosynthetic process (GO:0009113)3.21472021
77ribosomal small subunit assembly (GO:0000028)3.20425012
78* regulation of mitotic sister chromatid segregation (GO:0033047)3.20215303
79* regulation of sister chromatid segregation (GO:0033045)3.20215303
80* regulation of mitotic sister chromatid separation (GO:0010965)3.20215303
81maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.19774702
82telomere maintenance (GO:0000723)3.18624459
83regulation of nuclear cell cycle DNA replication (GO:0033262)3.17634790
84telomere organization (GO:0032200)3.17240809
85DNA catabolic process, exonucleolytic (GO:0000738)3.17038316
86* negative regulation of mitosis (GO:0045839)3.15658683
87folic acid-containing compound biosynthetic process (GO:0009396)3.15212209
88* negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.14887802
89* negative regulation of ligase activity (GO:0051352)3.14887802
90mismatch repair (GO:0006298)3.14516642
91regulation of sister chromatid cohesion (GO:0007063)3.14508964
92positive regulation of mitotic sister chromatid separation (GO:1901970)3.13105869
93positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.13105869
94positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.13105869
95maturation of 5.8S rRNA (GO:0000460)3.11496455
96synapsis (GO:0007129)3.10524673
97* mitotic cell cycle (GO:0000278)3.09958427
98maturation of SSU-rRNA (GO:0030490)3.09882117
99regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.09223440
100transcription-coupled nucleotide-excision repair (GO:0006283)3.09107242
101regulation of DNA endoreduplication (GO:0032875)3.08418501
102DNA geometric change (GO:0032392)3.01273624
103DNA duplex unwinding (GO:0032508)3.00908554
104cullin deneddylation (GO:0010388)3.00729985
105IMP metabolic process (GO:0046040)3.00407080
106ribosome assembly (GO:0042255)2.98634999
107spliceosomal snRNP assembly (GO:0000387)2.98381782
108pore complex assembly (GO:0046931)2.96626222
109chromosome condensation (GO:0030261)2.96087316
110formation of translation preinitiation complex (GO:0001731)2.95168852
111DNA synthesis involved in DNA repair (GO:0000731)2.95107489
112nuclear envelope organization (GO:0006998)2.95012339
113regulation of centriole replication (GO:0046599)2.93836173
114DNA topological change (GO:0006265)2.93586619
115ribosome biogenesis (GO:0042254)2.92887803
116G1/S transition of mitotic cell cycle (GO:0000082)2.89895810
117cell cycle G1/S phase transition (GO:0044843)2.89895810
118somatic hypermutation of immunoglobulin genes (GO:0016446)2.89220939
119somatic diversification of immune receptors via somatic mutation (GO:0002566)2.89220939
120* anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.88894124
121mitotic G2/M transition checkpoint (GO:0044818)2.88027507

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human5.96865439
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.59964284
3* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human4.12006611
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.93690153
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.19981666
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.06499680
7AR_21909140_ChIP-Seq_LNCAP_Human2.73352724
8* EST1_17652178_ChIP-ChIP_JURKAT_Human2.69531323
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.68210976
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.64315443
11GABP_17652178_ChIP-ChIP_JURKAT_Human2.57939736
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.49592813
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.42790635
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.38296032
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.33712308
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.32666706
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.32274833
18* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.29268461
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.14770783
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.14598573
21MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.14034947
22XRN2_22483619_ChIP-Seq_HELA_Human2.11683438
23VDR_23849224_ChIP-Seq_CD4+_Human2.09168550
24EGR1_19374776_ChIP-ChIP_THP-1_Human2.07208103
25KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.05993687
26E2F7_22180533_ChIP-Seq_HELA_Human10.3870316
27* MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.97615128
28DCP1A_22483619_ChIP-Seq_HELA_Human1.86967792
29MYCN_18555785_ChIP-Seq_MESCs_Mouse1.86478440
30FOXP3_21729870_ChIP-Seq_TREG_Human1.85325243
31* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.82815966
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.81831122
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.78612397
34ELK1_19687146_ChIP-ChIP_HELA_Human1.71441645
35TTF2_22483619_ChIP-Seq_HELA_Human1.70478741
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.70114058
37* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.68780725
38E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.66256991
39* GABP_19822575_ChIP-Seq_HepG2_Human1.64667472
40HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.61625268
41* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58941686
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.57020135
43NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.54341009
44YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.52435944
45* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.51830607
46TP63_19390658_ChIP-ChIP_HaCaT_Human1.49562528
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.48072592
48CIITA_25753668_ChIP-Seq_RAJI_Human1.39339093
49* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38556301
50KDM5A_27292631_Chip-Seq_BREAST_Human1.35936481
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.33391490
52MYC_22102868_ChIP-Seq_BL_Human1.32628813
53ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.29063304
54E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.25553270
55PADI4_21655091_ChIP-ChIP_MCF-7_Human1.24257143
56* EWS_26573619_Chip-Seq_HEK293_Human1.22182540
57HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21754063
58SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.21540595
59* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20006926
60YY1_21170310_ChIP-Seq_MESCs_Mouse1.19335622
61ERG_20887958_ChIP-Seq_HPC-7_Mouse1.17965376
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.17171121
63ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.17101592
64MYC_18940864_ChIP-ChIP_HL60_Human1.16629316
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.15288843
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.14983177
67RBPJ_22232070_ChIP-Seq_NCS_Mouse1.12512015
68CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11637417
69KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10083169
70CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.09232556
71SOX2_16153702_ChIP-ChIP_HESCs_Human1.08739248
72* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.08441776
73SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.07608763
74SALL1_21062744_ChIP-ChIP_HESCs_Human1.05690749
75CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.02954488
76* SOX2_18555785_ChIP-Seq_MESCs_Mouse1.01526816
77FUS_26573619_Chip-Seq_HEK293_Human0.99660699
78SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.98292595
79TFEB_21752829_ChIP-Seq_HELA_Human0.97748825
80ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95937809
81STAT3_1855785_ChIP-Seq_MESCs_Mouse0.95172150
82CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95090031
83* SPI1_23547873_ChIP-Seq_NB4_Human0.94345585
84SOX17_20123909_ChIP-Seq_XEN_Mouse0.94044953
85DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91806018
86NOTCH1_21737748_ChIP-Seq_TLL_Human0.90391648
87CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90194880
88POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88664233
89HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.87216079
90GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86903317
91KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.86251348
92NANOG_21062744_ChIP-ChIP_HESCs_Human0.80488356
93IRF1_19129219_ChIP-ChIP_H3396_Human0.80102234
94IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.79939817
95SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.79754676
96* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.77619635
97BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.77505113
98PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.77151467
99PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.76297838
100CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.75029602
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.74089203
102VDR_21846776_ChIP-Seq_THP-1_Human0.72264719
103NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.71434357
104ESR1_15608294_ChIP-ChIP_MCF-7_Human0.70379569
105VDR_22108803_ChIP-Seq_LS180_Human0.70213054
106NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.69260001
107TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.67284688
108ELK1_22589737_ChIP-Seq_MCF10A_Human0.66645240
109HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.66578844
110KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.64229568
111KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.63701611
112KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.63701611
113KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.63701611
114DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.63587743
115TCF3_18692474_ChIP-Seq_MEFs_Mouse0.62768483
116ZNF274_21170338_ChIP-Seq_K562_Hela0.62216234
117NANOG_16153702_ChIP-ChIP_HESCs_Human0.62064723
118* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.60815476
119MYB_21317192_ChIP-Seq_ERMYB_Mouse0.59919246

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.89876388
2* MP0010094_abnormal_chromosome_stability5.05672926
3* MP0003111_abnormal_nucleus_morphology4.74285588
4MP0004957_abnormal_blastocyst_morpholog4.35333621
5MP0008057_abnormal_DNA_replication4.30564120
6* MP0003077_abnormal_cell_cycle4.20156281
7MP0008058_abnormal_DNA_repair3.42407915
8MP0008007_abnormal_cellular_replicative3.08468970
9MP0008877_abnormal_DNA_methylation2.58595540
10* MP0008932_abnormal_embryonic_tissue2.58334754
11MP0003123_paternal_imprinting2.49825834
12MP0002396_abnormal_hematopoietic_system2.35706147
13MP0000350_abnormal_cell_proliferation2.28627027
14MP0001730_embryonic_growth_arrest2.17085042
15MP0003786_premature_aging2.10146046
16MP0003718_maternal_effect2.00253326
17MP0010307_abnormal_tumor_latency1.96163529
18MP0000490_abnormal_crypts_of1.83030540
19MP0010352_gastrointestinal_tract_polyps1.67675743
20MP0003806_abnormal_nucleotide_metabolis1.66807951
21* MP0001697_abnormal_embryo_size1.65963252
22MP0001672_abnormal_embryogenesis/_devel1.65287756
23MP0005380_embryogenesis_phenotype1.65287756
24MP0004808_abnormal_hematopoietic_stem1.61817413
25MP0003136_yellow_coat_color1.54759648
26MP0002210_abnormal_sex_determination1.48601890
27* MP0002085_abnormal_embryonic_tissue1.46339626
28* MP0002019_abnormal_tumor_incidence1.46118563
29MP0003984_embryonic_growth_retardation1.43335382
30MP0003121_genomic_imprinting1.42976462
31* MP0002080_prenatal_lethality1.41820184
32* MP0000313_abnormal_cell_death1.40356173
33MP0008789_abnormal_olfactory_epithelium1.39106014
34MP0002088_abnormal_embryonic_growth/wei1.38957584
35MP0003315_abnormal_perineum_morphology1.36950903
36MP0006035_abnormal_mitochondrial_morpho1.35186119
37MP0006292_abnormal_olfactory_placode1.31727436
38MP0002084_abnormal_developmental_patter1.29429438
39MP0002086_abnormal_extraembryonic_tissu1.28783340
40MP0000372_irregular_coat_pigmentation1.25677223
41MP0005076_abnormal_cell_differentiation1.25230066
42MP0001119_abnormal_female_reproductive1.24613741
43MP0001145_abnormal_male_reproductive1.23263968
44MP0001545_abnormal_hematopoietic_system1.22486980
45MP0005397_hematopoietic_system_phenotyp1.22486980
46MP0006072_abnormal_retinal_apoptosis1.22482670
47MP0001529_abnormal_vocalization1.22336982
48MP0006036_abnormal_mitochondrial_physio1.22045385
49MP0003890_abnormal_embryonic-extraembry1.21917425
50MP0009333_abnormal_splenocyte_physiolog1.20744417
51MP0001929_abnormal_gametogenesis1.18684716
52MP0002102_abnormal_ear_morphology1.18433635
53MP0004197_abnormal_fetal_growth/weight/1.17962672
54MP0000653_abnormal_sex_gland1.17918391
55MP0003763_abnormal_thymus_physiology1.13193752
56MP0002398_abnormal_bone_marrow1.12956235
57MP0002697_abnormal_eye_size1.12941335
58MP0003567_abnormal_fetal_cardiomyocyte1.12405040
59MP0010030_abnormal_orbit_morphology1.07116108
60MP0000703_abnormal_thymus_morphology1.05680682
61MP0002234_abnormal_pharynx_morphology1.01925149
62MP0002233_abnormal_nose_morphology1.01589563
63MP0003937_abnormal_limbs/digits/tail_de1.01027573
64MP0002722_abnormal_immune_system1.00879958
65MP0003119_abnormal_digestive_system1.00234042
66MP0005499_abnormal_olfactory_system0.99232150
67MP0005394_taste/olfaction_phenotype0.99232150
68MP0001293_anophthalmia0.98749941
69* MP0000689_abnormal_spleen_morphology0.96032799
70MP0006054_spinal_hemorrhage0.94778863
71MP0000049_abnormal_middle_ear0.90309578
72MP0000858_altered_metastatic_potential0.88590731
73MP0003941_abnormal_skin_development0.86944950
74MP0002429_abnormal_blood_cell0.84808674
75MP0000537_abnormal_urethra_morphology0.84490474
76MP0001346_abnormal_lacrimal_gland0.83308164
77MP0003698_abnormal_male_reproductive0.81423206
78MP0000647_abnormal_sebaceous_gland0.80699479
79MP0002160_abnormal_reproductive_system0.80518215
80MP0003699_abnormal_female_reproductive0.77507094
81MP0001915_intracranial_hemorrhage0.75043349
82MP0003186_abnormal_redox_activity0.74708740
83MP0005389_reproductive_system_phenotype0.74619178
84MP0000716_abnormal_immune_system0.74487364
85MP0002751_abnormal_autonomic_nervous0.73736795
86MP0009672_abnormal_birth_weight0.71793337
87* MP0005384_cellular_phenotype0.71754238
88* MP0005621_abnormal_cell_physiology0.71423305
89MP0001835_abnormal_antigen_presentation0.71053077
90MP0005391_vision/eye_phenotype0.70481309
91MP0003861_abnormal_nervous_system0.69797804
92MP0001188_hyperpigmentation0.69010834
93MP0003755_abnormal_palate_morphology0.68852190
94MP0000566_synostosis0.67484690
95MP0002111_abnormal_tail_morphology0.66488140
96MP0002095_abnormal_skin_pigmentation0.66292462
97MP0000579_abnormal_nail_morphology0.66036864
98MP0000631_abnormal_neuroendocrine_gland0.65499716
99MP0002132_abnormal_respiratory_system0.65335030
100MP0001800_abnormal_humoral_immune0.63171779
101MP0000428_abnormal_craniofacial_morphol0.61566128
102MP0009703_decreased_birth_body0.60645189
103MP0001919_abnormal_reproductive_system0.60502407
104MP0002452_abnormal_antigen_presenting0.60122551
105MP0005023_abnormal_wound_healing0.60100529
106MP0001727_abnormal_embryo_implantation0.60041523
107MP0002420_abnormal_adaptive_immunity0.60033201
108MP0009053_abnormal_anal_canal0.60018702
109MP0001286_abnormal_eye_development0.59925218
110MP0008995_early_reproductive_senescence0.59560129
111MP0001819_abnormal_immune_cell0.59331838
112MP0001853_heart_inflammation0.58735677
113MP0005408_hypopigmentation0.58250926
114MP0005187_abnormal_penis_morphology0.57963162
115MP0005253_abnormal_eye_physiology0.57953389
116MP0004133_heterotaxia0.57698608
117MP0003448_altered_tumor_morphology0.57657598
118MP0005671_abnormal_response_to0.57327735
119MP0003221_abnormal_cardiomyocyte_apopto0.57307307
120MP0002090_abnormal_vision0.57133034
121MP0002405_respiratory_system_inflammati0.56432680
122MP0009697_abnormal_copulation0.56197076
123MP0000358_abnormal_cell_content/0.55784167
124MP0003566_abnormal_cell_adhesion0.55323234
125MP0001177_atelectasis0.55253566
126MP0000477_abnormal_intestine_morphology0.54845188
127MP0002161_abnormal_fertility/fecundity0.54844046
128MP0000516_abnormal_urinary_system0.53632081
129MP0005367_renal/urinary_system_phenotyp0.53632081
130MP0005395_other_phenotype0.53521309
131MP0005501_abnormal_skin_physiology0.53354380
132MP0002092_abnormal_eye_morphology0.52164820
133MP0001764_abnormal_homeostasis0.51865696
134MP0002938_white_spotting0.51661715
135MP0002653_abnormal_ependyma_morphology0.51550204
136MP0000432_abnormal_head_morphology0.51180970
137MP0003935_abnormal_craniofacial_develop0.50836174
138MP0002075_abnormal_coat/hair_pigmentati0.50725272

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)5.46223991
2Birth length less than 3rd percentile (HP:0003561)5.42623036
3Chromosomal breakage induced by crosslinking agents (HP:0003221)5.21893081
4Breast hypoplasia (HP:0003187)4.07411077
5Abnormality of chromosome stability (HP:0003220)3.99054361
6Reticulocytopenia (HP:0001896)3.87579218
7Patellar aplasia (HP:0006443)3.78757301
8Meckel diverticulum (HP:0002245)3.74999198
9Abnormality of the preputium (HP:0100587)3.63370811
10Aplasia/Hypoplasia of the patella (HP:0006498)3.56434553
11Abnormality of the ileum (HP:0001549)3.52917505
12Aplasia/Hypoplasia of the uvula (HP:0010293)3.43938458
13Duodenal stenosis (HP:0100867)3.22849077
14Small intestinal stenosis (HP:0012848)3.22849077
15Aplastic anemia (HP:0001915)3.20347520
16Ectopic kidney (HP:0000086)3.19167468
17Myelodysplasia (HP:0002863)3.08409770
18Carpal bone hypoplasia (HP:0001498)3.07807644
19Oral leukoplakia (HP:0002745)3.06897478
20Absent radius (HP:0003974)3.04586090
21Medulloblastoma (HP:0002885)2.99609150
22Impulsivity (HP:0100710)2.88405740
23Abnormal lung lobation (HP:0002101)2.88144458
24Absent forearm bone (HP:0003953)2.83701220
25Aplasia involving forearm bones (HP:0009822)2.83701220
26Abnormality of the labia minora (HP:0012880)2.83105349
27Selective tooth agenesis (HP:0001592)2.82077948
28Absent thumb (HP:0009777)2.81216199
29Abnormality of cells of the erythroid lineage (HP:0012130)2.79946760
30Abnormal number of erythroid precursors (HP:0012131)2.77594148
31Duplicated collecting system (HP:0000081)2.74024655
32Bone marrow hypocellularity (HP:0005528)2.71925171
33Abnormality of the anterior horn cell (HP:0006802)2.71467351
34Degeneration of anterior horn cells (HP:0002398)2.71467351
35Acute necrotizing encephalopathy (HP:0006965)2.69584713
36Colon cancer (HP:0003003)2.66843673
37Sloping forehead (HP:0000340)2.60533449
38Abnormality of the duodenum (HP:0002246)2.58785908
39Acute encephalopathy (HP:0006846)2.55102821
40Supernumerary spleens (HP:0009799)2.49434619
41Agnosia (HP:0010524)2.49377753
42Cortical dysplasia (HP:0002539)2.48978124
43Abnormality of the renal collecting system (HP:0004742)2.48615184
44Horseshoe kidney (HP:0000085)2.48048520
45Clubbing of toes (HP:0100760)2.47774226
46Abnormality of the carotid arteries (HP:0005344)2.44940153
47Abnormal mitochondria in muscle tissue (HP:0008316)2.43673403
48Nephroblastoma (Wilms tumor) (HP:0002667)2.43099710
49Rough bone trabeculation (HP:0100670)2.39217064
50Increased nuchal translucency (HP:0010880)2.38490981
51Short thumb (HP:0009778)2.37982781
52Rhabdomyosarcoma (HP:0002859)2.35683674
53Triphalangeal thumb (HP:0001199)2.32168124
54Tracheoesophageal fistula (HP:0002575)2.31718892
55Premature graying of hair (HP:0002216)2.30172780
5611 pairs of ribs (HP:0000878)2.29887346
57Increased hepatocellular lipid droplets (HP:0006565)2.27442734
58Embryonal renal neoplasm (HP:0011794)2.25533168
59Increased CSF lactate (HP:0002490)2.22662537
60Increased serum pyruvate (HP:0003542)2.20384563
61Abnormality of glycolysis (HP:0004366)2.19512539
62Facial hemangioma (HP:0000329)2.18999392
63Cafe-au-lait spot (HP:0000957)2.18908254
64Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.17467208
65Ependymoma (HP:0002888)2.15933707
66Multiple enchondromatosis (HP:0005701)2.15130177
67Volvulus (HP:0002580)2.14673962
68Pallor (HP:0000980)2.14042260
69Mitochondrial inheritance (HP:0001427)2.12748725
70Neoplasm of the pancreas (HP:0002894)2.11044944
71Microvesicular hepatic steatosis (HP:0001414)2.10697058
72Abnormality of DNA repair (HP:0003254)2.09821619
73Progressive macrocephaly (HP:0004481)2.09791147
74Cleft eyelid (HP:0000625)2.08289752
75Abnormality of methionine metabolism (HP:0010901)2.08278252
76Atresia of the external auditory canal (HP:0000413)2.08022307
77Microretrognathia (HP:0000308)2.07340838
78Cellular immunodeficiency (HP:0005374)2.04401986
79Short 4th metacarpal (HP:0010044)2.04094392
80Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.04094392
81Abnormal number of incisors (HP:0011064)2.03896415
82Septo-optic dysplasia (HP:0100842)2.02864142
83Aplasia/Hypoplasia of the sternum (HP:0006714)2.01436328
84Lipid accumulation in hepatocytes (HP:0006561)2.00758235
85Abnormal spermatogenesis (HP:0008669)1.99852982
86Slender long bone (HP:0003100)1.99599055
87Hypoplastic pelvis (HP:0008839)1.99562858
88Hypoplasia of the capital femoral epiphysis (HP:0003090)1.94866111
89Deviation of the thumb (HP:0009603)1.93565698
90Cerebral edema (HP:0002181)1.93360502
91Choanal atresia (HP:0000453)1.92139622
92Absent septum pellucidum (HP:0001331)1.92139423
93Abnormality of the fetal cardiovascular system (HP:0010948)1.92014518
94Abnormal umbilical cord blood vessels (HP:0011403)1.92014518
95Single umbilical artery (HP:0001195)1.92014518
96Megaloblastic anemia (HP:0001889)1.91763846
97Squamous cell carcinoma (HP:0002860)1.91584395
98Proximal placement of thumb (HP:0009623)1.91558907
99Abnormality of the septum pellucidum (HP:0007375)1.91330615
100Macrocytic anemia (HP:0001972)1.91274920
101Lymphoma (HP:0002665)1.90290163
102Embryonal neoplasm (HP:0002898)1.89749790
103Glioma (HP:0009733)1.88555219
104Increased serum lactate (HP:0002151)1.86924600
105Basal cell carcinoma (HP:0002671)1.86439494
106Type I transferrin isoform profile (HP:0003642)1.84922772
107Pancreatic islet-cell hyperplasia (HP:0004510)1.84517387
108Abnormality of chromosome segregation (HP:0002916)1.84211392
109Acute myeloid leukemia (HP:0004808)1.83967314
110Hepatocellular necrosis (HP:0001404)1.83544194
111High pitched voice (HP:0001620)1.82588093
112Hypoplasia of the pons (HP:0012110)1.82060441
113Abnormality of the pons (HP:0007361)1.81010944
114Secondary amenorrhea (HP:0000869)1.79453350
115Breast aplasia (HP:0100783)1.79219903
116Ovarian neoplasm (HP:0100615)1.79078458
117Prominent nose (HP:0000448)1.78095097
118Pancytopenia (HP:0001876)1.77833108
119Abdominal situs inversus (HP:0003363)1.77509984
120Abnormality of abdominal situs (HP:0011620)1.77509984
121Neoplasm of the colon (HP:0100273)1.76914222
122Abnormality of serum amino acid levels (HP:0003112)1.76749037
123Optic nerve coloboma (HP:0000588)1.76267487
124Facial cleft (HP:0002006)1.76251558
125Abnormal trabecular bone morphology (HP:0100671)1.75759430
126Premature ovarian failure (HP:0008209)1.75548179
127Oligodactyly (hands) (HP:0001180)1.75257099
128Aplasia/Hypoplasia of the breasts (HP:0010311)1.74667624
129Arteriovenous malformation (HP:0100026)1.74666388
130Aplasia/Hypoplasia of the sacrum (HP:0008517)1.74633264
131Abnormality of pyrimidine metabolism (HP:0004353)1.73054219
132Hyperglycinemia (HP:0002154)1.71111593
133Short middle phalanx of the 5th finger (HP:0004220)1.70510068
134Capillary hemangiomas (HP:0005306)1.69028975
135Pulmonary fibrosis (HP:0002206)1.68666523
136Abnormality of cochlea (HP:0000375)1.68533089
137Hepatic necrosis (HP:0002605)1.68387473
138Overlapping toe (HP:0001845)1.68032243
139Reduced antithrombin III activity (HP:0001976)1.67806331
140Abnormality of aspartate family amino acid metabolism (HP:0010899)1.67207452
141Stenosis of the external auditory canal (HP:0000402)1.66700210
142Oligodactyly (HP:0012165)1.66683005
143Duplication of thumb phalanx (HP:0009942)1.64048135
144Hyperalaninemia (HP:0003348)1.61212295

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.86984442
2BUB14.70275672
3WEE14.33760170
4EIF2AK13.22307344
5NEK23.12576187
6PLK42.85806228
7TTK2.83816323
8SRPK12.60644460
9ACVR1B2.55535145
10BRSK22.51313708
11VRK22.49673585
12PLK12.34658878
13NEK12.26098952
14MKNK12.03919408
15AURKB1.92995447
16MST41.92857818
17EIF2AK31.87523710
18VRK11.79809369
19ATR1.74121086
20MKNK21.72916990
21NME21.70893796
22PLK31.69193517
23TRIM281.68124698
24CHEK21.66094225
25BRSK11.64771859
26CDK71.63915464
27RPS6KA41.59590901
28CCNB11.54080690
29STK41.51788014
30PBK1.50477292
31TLK11.44357033
32CDK121.41777175
33TAF11.40894449
34MAP3K81.39526794
35STK161.33327030
36AURKA1.32754400
37STK101.31466121
38RPS6KB21.30966921
39CDK41.30334573
40NME11.28394325
41TSSK61.23214922
42CHEK11.22989017
43EIF2AK21.19069280
44DYRK31.18456166
45TESK21.15409735
46EEF2K1.12946372
47CDK81.11777275
48ZAK1.10120023
49PASK1.06675698
50BRAF1.04554783
51MELK1.03918905
52PNCK1.03313898
53CLK11.00470261
54ATM0.99879755
55STK30.97521811
56TNIK0.97366048
57BMPR1B0.96739717
58WNK30.96667191
59PIM10.86645889
60SCYL20.81560357
61PDK20.80506897
62CDK20.80389620
63LATS10.79910858
64STK38L0.79063666
65NEK90.78049736
66TGFBR10.76594256
67CDK60.74836780
68ERBB30.70289927
69CDK10.69465571
70BCR0.68899749
71PAK40.67280134
72EPHA20.67009754
73CSNK2A10.60446872
74BRD40.59647022
75FLT30.58044155
76MAP4K10.57560162
77PLK20.55837594
78PAK10.50524371
79CSNK1G10.50090065
80CSNK2A20.48969315
81MAP3K60.46505022
82ERBB40.45214005
83LATS20.43981316
84CSNK1G30.43180156
85TEC0.42156207
86CDK30.40690412
87RPS6KA50.40557869
88JAK30.40045602
89CDK180.39648369
90PRKCI0.38393558
91CSNK1E0.36904959
92ALK0.36667668
93FGFR10.36572681
94CDK150.35870123
95NUAK10.35790412
96CDK11A0.34690806
97CDK90.34652190
98MAP3K100.33203237
99LRRK20.32767035
100CDK140.32274241
101KIT0.31108175
102MARK30.30495753
103BTK0.30052005
104IRAK40.29901255
105CSNK1G20.29587920
106MAP4K20.29505129
107ABL20.29163037
108CSNK1A1L0.29122536
109PRKDC0.28548921
110CDK190.28350180
111BCKDK0.28045849
112TESK10.27720347
113PKN20.27077639
114MAPKAPK30.26466635
115RAF10.25670665
116MINK10.25244707
117UHMK10.25172841
118CHUK0.24758015
119KDR0.24572606
120DYRK20.23917221
121STK240.23752881
122YES10.23728275
123MAPK140.22516969
124CSF1R0.22493805
125AKT20.21575788
126AKT10.21097883
127PIM20.20875504
128MET0.20103250
129LYN0.19731325
130TRPM70.18292436
131STK390.18110746
132MOS0.17069360

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.28025007
2Mismatch repair_Homo sapiens_hsa034304.47302468
3Homologous recombination_Homo sapiens_hsa034403.62178516
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.35865538
5* Cell cycle_Homo sapiens_hsa041103.31145037
6Base excision repair_Homo sapiens_hsa034103.24539765
7Nucleotide excision repair_Homo sapiens_hsa034203.08159997
8Spliceosome_Homo sapiens_hsa030403.04071884
9RNA polymerase_Homo sapiens_hsa030203.01567847
10RNA transport_Homo sapiens_hsa030132.97595559
11Fanconi anemia pathway_Homo sapiens_hsa034602.77500728
12Proteasome_Homo sapiens_hsa030502.61444047
13Ribosome_Homo sapiens_hsa030102.60648937
14One carbon pool by folate_Homo sapiens_hsa006702.42340590
15Pyrimidine metabolism_Homo sapiens_hsa002402.39285556
16Non-homologous end-joining_Homo sapiens_hsa034502.32458897
17Basal transcription factors_Homo sapiens_hsa030222.24130214
18RNA degradation_Homo sapiens_hsa030182.15260755
19p53 signaling pathway_Homo sapiens_hsa041151.92228606
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.86292955
21Parkinsons disease_Homo sapiens_hsa050121.74268432
22Oxidative phosphorylation_Homo sapiens_hsa001901.72820389
23mRNA surveillance pathway_Homo sapiens_hsa030151.72480696
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.52246943
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.39776447
26Pyruvate metabolism_Homo sapiens_hsa006201.38887632
27Systemic lupus erythematosus_Homo sapiens_hsa053221.31773821
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.28476947
29Purine metabolism_Homo sapiens_hsa002301.27115012
30Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.24776806
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.23061394
32Herpes simplex infection_Homo sapiens_hsa051681.22503749
33Propanoate metabolism_Homo sapiens_hsa006401.19362139
34* Oocyte meiosis_Homo sapiens_hsa041141.18734688
35Epstein-Barr virus infection_Homo sapiens_hsa051691.17138109
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.13998226
37Steroid biosynthesis_Homo sapiens_hsa001001.10801042
38* Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.07181073
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.05731305
40Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.02836376
41Viral carcinogenesis_Homo sapiens_hsa052030.98512523
42Fatty acid elongation_Homo sapiens_hsa000620.97208629
43Carbon metabolism_Homo sapiens_hsa012000.95567350
44Alzheimers disease_Homo sapiens_hsa050100.93635198
45Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.89132991
46Antigen processing and presentation_Homo sapiens_hsa046120.87101869
47* HTLV-I infection_Homo sapiens_hsa051660.81873843
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.80354720
49MicroRNAs in cancer_Homo sapiens_hsa052060.79131601
50Small cell lung cancer_Homo sapiens_hsa052220.75543963
51Vitamin B6 metabolism_Homo sapiens_hsa007500.74119918
52Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70534982
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.65952592
54Thyroid cancer_Homo sapiens_hsa052160.65144820
55Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.64707652
56Primary immunodeficiency_Homo sapiens_hsa053400.63852886
57NF-kappa B signaling pathway_Homo sapiens_hsa040640.60234237
58Transcriptional misregulation in cancer_Homo sapiens_hsa052020.57501816
59Legionellosis_Homo sapiens_hsa051340.56794553
60Pentose phosphate pathway_Homo sapiens_hsa000300.56332583
61Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.56207677
62TGF-beta signaling pathway_Homo sapiens_hsa043500.55636509
63Cysteine and methionine metabolism_Homo sapiens_hsa002700.55209022
64Metabolic pathways_Homo sapiens_hsa011000.54841202
65Measles_Homo sapiens_hsa051620.54405916
66Apoptosis_Homo sapiens_hsa042100.53218067
67Selenocompound metabolism_Homo sapiens_hsa004500.52041718
68Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51337086
69Hepatitis B_Homo sapiens_hsa051610.51089193
70Protein export_Homo sapiens_hsa030600.49642710
71Drug metabolism - other enzymes_Homo sapiens_hsa009830.49475812
72Folate biosynthesis_Homo sapiens_hsa007900.48937302
73Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.46186530
74Hematopoietic cell lineage_Homo sapiens_hsa046400.45549300
75Colorectal cancer_Homo sapiens_hsa052100.45024888
76Intestinal immune network for IgA production_Homo sapiens_hsa046720.42997331
77Shigellosis_Homo sapiens_hsa051310.42891946
78Alcoholism_Homo sapiens_hsa050340.41879466
79NOD-like receptor signaling pathway_Homo sapiens_hsa046210.41090305
80Influenza A_Homo sapiens_hsa051640.41073919
81Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.38839443
82Biosynthesis of amino acids_Homo sapiens_hsa012300.36891875
83Pancreatic cancer_Homo sapiens_hsa052120.36564715
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.35292750
85Chronic myeloid leukemia_Homo sapiens_hsa052200.35110426
86Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.34841857
87RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34669437
88Hippo signaling pathway_Homo sapiens_hsa043900.34145563
89Arginine and proline metabolism_Homo sapiens_hsa003300.32659967
90Asthma_Homo sapiens_hsa053100.32518397
91Fatty acid metabolism_Homo sapiens_hsa012120.31735665
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31667460
93Lysine degradation_Homo sapiens_hsa003100.31198295
94Glutathione metabolism_Homo sapiens_hsa004800.31069280
95Cardiac muscle contraction_Homo sapiens_hsa042600.31037941
96N-Glycan biosynthesis_Homo sapiens_hsa005100.28499183
97Hedgehog signaling pathway_Homo sapiens_hsa043400.28195422
98Huntingtons disease_Homo sapiens_hsa050160.27637129
99Allograft rejection_Homo sapiens_hsa053300.27073046
100Pathways in cancer_Homo sapiens_hsa052000.26603623
101Wnt signaling pathway_Homo sapiens_hsa043100.26542014
102Viral myocarditis_Homo sapiens_hsa054160.26161863
103Leishmaniasis_Homo sapiens_hsa051400.25748421
104Notch signaling pathway_Homo sapiens_hsa043300.24116616
105Bladder cancer_Homo sapiens_hsa052190.22871479
106Peroxisome_Homo sapiens_hsa041460.22648977
107Basal cell carcinoma_Homo sapiens_hsa052170.22412507
108Sulfur metabolism_Homo sapiens_hsa009200.22403115
109Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.22240341
110Adherens junction_Homo sapiens_hsa045200.22080751
111Vitamin digestion and absorption_Homo sapiens_hsa049770.21903393
112Prostate cancer_Homo sapiens_hsa052150.21757694
113Graft-versus-host disease_Homo sapiens_hsa053320.20842528
114FoxO signaling pathway_Homo sapiens_hsa040680.19795692
115Cyanoamino acid metabolism_Homo sapiens_hsa004600.18762234
116Jak-STAT signaling pathway_Homo sapiens_hsa046300.18711022
117HIF-1 signaling pathway_Homo sapiens_hsa040660.18357141
118Butanoate metabolism_Homo sapiens_hsa006500.18178700
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.17498366
120Fatty acid degradation_Homo sapiens_hsa000710.16720543
121Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.16305650
122Autoimmune thyroid disease_Homo sapiens_hsa053200.14633211
123Non-small cell lung cancer_Homo sapiens_hsa052230.14374394
124Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.14006147
125Acute myeloid leukemia_Homo sapiens_hsa052210.13932084
126Melanoma_Homo sapiens_hsa052180.13629896
127beta-Alanine metabolism_Homo sapiens_hsa004100.13125938
128Arachidonic acid metabolism_Homo sapiens_hsa005900.12083038
129Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.12013192
130Caffeine metabolism_Homo sapiens_hsa002320.12010430
131Phototransduction_Homo sapiens_hsa047440.11979701
132Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.11126630
133Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.10367422
134Sulfur relay system_Homo sapiens_hsa041220.10029148
135Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.09894743
136Renin-angiotensin system_Homo sapiens_hsa046140.09333455
137mTOR signaling pathway_Homo sapiens_hsa041500.09122685
138Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.09058402
139Tyrosine metabolism_Homo sapiens_hsa003500.04831930
140Olfactory transduction_Homo sapiens_hsa047400.03201756

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »