Rank | Gene Set | Z-score |
---|---|---|
1 | angiotensin maturation (GO:0002003) | 5.45910131 |
2 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.81060023 |
3 | microglial cell activation (GO:0001774) | 4.56314638 |
4 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 4.55510198 |
5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.51645539 |
6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.51645539 |
7 | modulation by symbiont of host immune response (GO:0052553) | 4.51645539 |
8 | positive regulation by symbiont of host defense response (GO:0052509) | 4.51645539 |
9 | modulation by symbiont of host defense response (GO:0052031) | 4.51645539 |
10 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.51645539 |
11 | positive regulation of monocyte chemotaxis (GO:0090026) | 4.16213067 |
12 | virion attachment to host cell (GO:0019062) | 4.13178159 |
13 | adhesion of symbiont to host cell (GO:0044650) | 4.13178159 |
14 | macrophage activation involved in immune response (GO:0002281) | 4.07296177 |
15 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.05390586 |
16 | regulation of interferon-alpha production (GO:0032647) | 3.85132081 |
17 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.82442675 |
18 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.78837135 |
19 | neutrophil activation involved in immune response (GO:0002283) | 3.75598633 |
20 | macrophage activation (GO:0042116) | 3.70821463 |
21 | adhesion of symbiont to host (GO:0044406) | 3.67439935 |
22 | positive regulation of interferon-alpha production (GO:0032727) | 3.58284810 |
23 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 3.51585406 |
24 | epoxygenase P450 pathway (GO:0019373) | 3.41441078 |
25 | pinocytosis (GO:0006907) | 3.38995266 |
26 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.38142130 |
27 | regulation of monocyte chemotaxis (GO:0090025) | 3.35689257 |
28 | positive regulation of antigen processing and presentation (GO:0002579) | 3.32685689 |
29 | lipoprotein transport (GO:0042953) | 3.30331545 |
30 | regulation of guanylate cyclase activity (GO:0031282) | 3.30130501 |
31 | phospholipid efflux (GO:0033700) | 3.25859748 |
32 | fat-soluble vitamin biosynthetic process (GO:0042362) | 3.25313765 |
33 | negative regulation of granulocyte differentiation (GO:0030853) | 3.25145552 |
34 | regulation of mononuclear cell migration (GO:0071675) | 3.21639708 |
35 | positive regulation of macrophage differentiation (GO:0045651) | 3.19853321 |
36 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.18069857 |
37 | regulation of macrophage chemotaxis (GO:0010758) | 3.15647119 |
38 | peptide catabolic process (GO:0043171) | 3.14745201 |
39 | negative regulation of mast cell activation (GO:0033004) | 3.11267910 |
40 | phagocytosis, engulfment (GO:0006911) | 3.10403292 |
41 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.09595100 |
42 | positive regulation of chemokine secretion (GO:0090197) | 3.08712384 |
43 | detection of molecule of bacterial origin (GO:0032490) | 3.06534952 |
44 | fructose metabolic process (GO:0006000) | 3.04229470 |
45 | I-kappaB phosphorylation (GO:0007252) | 3.00488851 |
46 | eosinophil chemotaxis (GO:0048245) | 2.99296821 |
47 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.95586778 |
48 | response to host immune response (GO:0052572) | 2.95586778 |
49 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.92234582 |
50 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 2.92051625 |
51 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.91661789 |
52 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.90851200 |
53 | response to peptidoglycan (GO:0032494) | 2.90492692 |
54 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.88587810 |
55 | myeloid cell activation involved in immune response (GO:0002275) | 2.85595520 |
56 | developmental pigmentation (GO:0048066) | 2.85411525 |
57 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.85196828 |
58 | positive regulation of smooth muscle cell migration (GO:0014911) | 2.85149686 |
59 | regulation of triglyceride catabolic process (GO:0010896) | 2.83955419 |
60 | NADH metabolic process (GO:0006734) | 2.83071280 |
61 | negative regulation of B cell proliferation (GO:0030889) | 2.81789747 |
62 | regulation of antigen processing and presentation (GO:0002577) | 2.80244951 |
63 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 2.78313813 |
64 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 2.78313813 |
65 | endocrine process (GO:0050886) | 2.78313813 |
66 | activated T cell proliferation (GO:0050798) | 2.77547920 |
67 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 2.73769775 |
68 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.68677901 |
69 | response to host (GO:0075136) | 2.68677901 |
70 | response to host defenses (GO:0052200) | 2.68677901 |
71 | dendritic cell migration (GO:0036336) | 2.68286966 |
72 | dendritic cell chemotaxis (GO:0002407) | 2.66695704 |
73 | respiratory burst (GO:0045730) | 2.65646351 |
74 | monocyte chemotaxis (GO:0002548) | 2.64816792 |
75 | oligosaccharide catabolic process (GO:0009313) | 2.64611803 |
76 | cytidine metabolic process (GO:0046087) | 2.64529581 |
77 | cytidine catabolic process (GO:0006216) | 2.64529581 |
78 | cytidine deamination (GO:0009972) | 2.64529581 |
79 | intestinal epithelial cell development (GO:0060576) | 2.62336884 |
80 | regulation of regulatory T cell differentiation (GO:0045589) | 2.62215816 |
81 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 2.62040516 |
82 | positive regulation of lymphocyte migration (GO:2000403) | 2.62028044 |
83 | regulation of cellular extravasation (GO:0002691) | 2.61265422 |
84 | regulation of cholesterol esterification (GO:0010872) | 2.59398673 |
85 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.59280558 |
86 | cellular extravasation (GO:0045123) | 2.59264891 |
87 | hormone catabolic process (GO:0042447) | 2.58016347 |
88 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.56783512 |
89 | eosinophil migration (GO:0072677) | 2.56608462 |
90 | drug metabolic process (GO:0017144) | 2.56214261 |
91 | peptide hormone processing (GO:0016486) | 2.55914848 |
92 | regulation of systemic arterial blood pressure (GO:0003073) | 2.54135614 |
93 | positive regulation of cAMP-mediated signaling (GO:0043950) | 2.53976896 |
94 | tolerance induction (GO:0002507) | 2.53852745 |
95 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 2.53764741 |
96 | granulocyte activation (GO:0036230) | 2.52482688 |
97 | regulation of T cell tolerance induction (GO:0002664) | 2.52023168 |
98 | macroautophagy (GO:0016236) | 2.51573261 |
99 | cellular response to ethanol (GO:0071361) | 2.50602482 |
100 | positive regulation of guanylate cyclase activity (GO:0031284) | 2.50342484 |
101 | renal system process involved in regulation of blood volume (GO:0001977) | 2.49972271 |
102 | negative regulation of interleukin-12 production (GO:0032695) | 2.49271638 |
103 | lymphocyte chemotaxis (GO:0048247) | 2.48235190 |
104 | regulation of cholesterol storage (GO:0010885) | 2.47612476 |
105 | T cell migration (GO:0072678) | 2.46874586 |
106 | negative T cell selection (GO:0043383) | 2.46725586 |
107 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.45639098 |
108 | T-helper cell differentiation (GO:0042093) | 2.45639098 |
109 | positive regulation of T cell migration (GO:2000406) | 2.45543004 |
110 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.44799317 |
111 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.43394135 |
112 | immunoglobulin mediated immune response (GO:0016064) | 2.41944121 |
113 | positive regulation of cholesterol efflux (GO:0010875) | 2.41654347 |
114 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.41055498 |
115 | regulation of chemokine secretion (GO:0090196) | 2.39926099 |
116 | intestinal absorption (GO:0050892) | 2.39695059 |
117 | neutrophil activation (GO:0042119) | 2.39263647 |
118 | complement activation, classical pathway (GO:0006958) | 2.38959211 |
119 | regulation of calcium-mediated signaling (GO:0050848) | 2.38840816 |
120 | phospholipid homeostasis (GO:0055091) | 2.38276055 |
121 | low-density lipoprotein particle remodeling (GO:0034374) | 2.37399227 |
122 | regulation of protein glycosylation (GO:0060049) | 2.35867442 |
123 | regulation of lymphocyte chemotaxis (GO:1901623) | 2.34898056 |
124 | myeloid leukocyte activation (GO:0002274) | 2.34718152 |
125 | phenylpropanoid metabolic process (GO:0009698) | 2.34544079 |
126 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.33837110 |
127 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.33375018 |
128 | regulation of bile acid biosynthetic process (GO:0070857) | 2.33284584 |
129 | negative thymic T cell selection (GO:0045060) | 2.32196090 |
130 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.31767040 |
131 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.31276796 |
132 | regulation of cGMP biosynthetic process (GO:0030826) | 2.31267924 |
133 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 2.30801051 |
134 | positive T cell selection (GO:0043368) | 2.29623506 |
135 | toxin transport (GO:1901998) | 2.29567240 |
136 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.29232530 |
137 | response to nitric oxide (GO:0071731) | 2.26732036 |
138 | positive regulation of heat generation (GO:0031652) | 2.26307636 |
139 | positive regulation of leukocyte chemotaxis (GO:0002690) | 2.25892204 |
140 | reverse cholesterol transport (GO:0043691) | 2.25493665 |
141 | negative regulation of lipid storage (GO:0010888) | 2.22738052 |
142 | protein-lipid complex assembly (GO:0065005) | 2.22539661 |
143 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.22340430 |
144 | negative regulation of cell killing (GO:0031342) | 2.22340430 |
145 | T cell differentiation involved in immune response (GO:0002292) | 2.22254909 |
146 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.22254909 |
147 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.22254909 |
148 | regulation of fever generation (GO:0031620) | 2.22167375 |
149 | plasma lipoprotein particle assembly (GO:0034377) | 2.21305752 |
150 | plasma lipoprotein particle remodeling (GO:0034369) | 2.20877958 |
151 | protein-lipid complex remodeling (GO:0034368) | 2.20877958 |
152 | macromolecular complex remodeling (GO:0034367) | 2.20877958 |
153 | positive regulation of cholesterol transport (GO:0032376) | 2.20456636 |
154 | positive regulation of sterol transport (GO:0032373) | 2.20456636 |
155 | high-density lipoprotein particle remodeling (GO:0034375) | 2.20409366 |
156 | negative regulation of bone resorption (GO:0045779) | 2.20057039 |
157 | glomerulus development (GO:0032835) | 2.20023202 |
158 | complement activation (GO:0006956) | 2.19764723 |
159 | keratan sulfate catabolic process (GO:0042340) | 2.19581795 |
160 | regulation of lymphocyte migration (GO:2000401) | 2.19475450 |
161 | lipoprotein metabolic process (GO:0042157) | 2.19331187 |
162 | regulation of macrophage differentiation (GO:0045649) | 2.18542080 |
163 | cholesterol efflux (GO:0033344) | 2.18540276 |
164 | regulation of pigment cell differentiation (GO:0050932) | 2.13127010 |
165 | cellular response to nitric oxide (GO:0071732) | 2.12894334 |
166 | T cell selection (GO:0045058) | 2.12707118 |
167 | cellular response to interleukin-15 (GO:0071350) | 2.12212150 |
168 | positive thymic T cell selection (GO:0045059) | 2.10666432 |
169 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.10489605 |
170 | T cell costimulation (GO:0031295) | 2.09769133 |
171 | cellular response to reactive nitrogen species (GO:1902170) | 2.09681824 |
172 | regulation of transforming growth factor beta1 production (GO:0032908) | 2.09548206 |
173 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.09191659 |
174 | lymphocyte costimulation (GO:0031294) | 2.07946149 |
175 | flavonoid metabolic process (GO:0009812) | 2.07912812 |
176 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.07124373 |
177 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.06508614 |
178 | protein-lipid complex subunit organization (GO:0071825) | 2.04840632 |
179 | regulation of cGMP metabolic process (GO:0030823) | 2.04480423 |
180 | cellular glucuronidation (GO:0052695) | 2.03943724 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.76362304 |
2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.03745382 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.80267556 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.33622048 |
5 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.25061533 |
6 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.04042194 |
7 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.70301353 |
8 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.44432365 |
9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.43562987 |
10 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.40488899 |
11 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.39921882 |
12 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.31330370 |
13 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.87906278 |
14 | * VDR_24787735_ChIP-Seq_THP-1_Human | 1.80685427 |
15 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.76695118 |
16 | * RUNX_20019798_ChIP-Seq_JUKART_Human | 1.68408226 |
17 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.62787374 |
18 | * PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.55791523 |
19 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.53080461 |
20 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.52920679 |
21 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.49571891 |
22 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.47601749 |
23 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.46861892 |
24 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.46434850 |
25 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.40011415 |
26 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.38345324 |
27 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.34059666 |
28 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.34051032 |
29 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.28371609 |
30 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.27589362 |
31 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.26142720 |
32 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.25748240 |
33 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.25371255 |
34 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.24851481 |
35 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.24770645 |
36 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.21985350 |
37 | CJUN_26792858_Chip-Seq_BT549_Human | 1.21604072 |
38 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.21042278 |
39 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.20391416 |
40 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.18676757 |
41 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.18655275 |
42 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.14303815 |
43 | * CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.13921364 |
44 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.13399059 |
45 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.11031224 |
46 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.10536868 |
47 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.09064358 |
48 | * NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.07981896 |
49 | * NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.07981896 |
50 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.07312333 |
51 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.06238149 |
52 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.05567768 |
53 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.05349416 |
54 | * TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.04684710 |
55 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.04131029 |
56 | * SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.03881557 |
57 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.03631258 |
58 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.03607277 |
59 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.03507388 |
60 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.02865882 |
61 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.02588412 |
62 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.02372742 |
63 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.02023992 |
64 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.01521915 |
65 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.00179015 |
66 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.99970694 |
67 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.99900410 |
68 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.99782184 |
69 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.99533614 |
70 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98583791 |
71 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.97419038 |
72 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.97161579 |
73 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.97143881 |
74 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.96796628 |
75 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.96072459 |
76 | * CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.96017175 |
77 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.95986465 |
78 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.95415416 |
79 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.95319125 |
80 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.94384100 |
81 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.93540946 |
82 | TP53_16413492_ChIP-PET_HCT116_Human | 0.93435194 |
83 | SPI1_23127762_ChIP-Seq_K562_Human | 0.93117071 |
84 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.92037444 |
85 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.91789931 |
86 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.91702503 |
87 | GATA1_22025678_ChIP-Seq_K562_Human | 0.91032680 |
88 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.90588148 |
89 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.90078965 |
90 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90059344 |
91 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.89956918 |
92 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.89745036 |
93 | * PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.89704117 |
94 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.88723642 |
95 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.88718909 |
96 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88197150 |
97 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.87397075 |
98 | RXR_22108803_ChIP-Seq_LS180_Human | 0.87295386 |
99 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.87087731 |
100 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.86749944 |
101 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.86716656 |
102 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.86708731 |
103 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.85700154 |
104 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.85428545 |
105 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85322140 |
106 | * BCAT_22108803_ChIP-Seq_LS180_Human | 0.84840523 |
107 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.84826430 |
108 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.84826367 |
109 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.84700949 |
110 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.83920844 |
111 | * GATA2_19941826_ChIP-Seq_K562_Human | 0.83530740 |
112 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.83363093 |
113 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.82543656 |
114 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.82543656 |
115 | * PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.82449687 |
116 | P300_19829295_ChIP-Seq_ESCs_Human | 0.81829307 |
117 | * TP63_23658742_ChIP-Seq_EP156T_Human | 0.81827512 |
118 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.81660201 |
119 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.80949425 |
120 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.80697448 |
121 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.80413494 |
122 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.80308722 |
123 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.79861839 |
124 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.79671840 |
125 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.79615635 |
126 | * TCF4_22108803_ChIP-Seq_LS180_Human | 0.79504565 |
127 | * PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.79333120 |
128 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.79311042 |
129 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.79020193 |
130 | * SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.78765749 |
131 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.78656404 |
132 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.78548605 |
133 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.78051997 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005058_abnormal_lysosome_morphology | 3.25218638 |
2 | MP0003191_abnormal_cellular_cholesterol | 3.24458051 |
3 | MP0001835_abnormal_antigen_presentation | 3.23765699 |
4 | MP0006082_CNS_inflammation | 3.18578051 |
5 | MP0002148_abnormal_hypersensitivity_rea | 3.08471420 |
6 | MP0003303_peritoneal_inflammation | 3.08265896 |
7 | MP0010234_abnormal_vibrissa_follicle | 3.06492332 |
8 | MP0009840_abnormal_foam_cell | 2.99935436 |
9 | MP0009379_abnormal_foot_pigmentation | 2.72712984 |
10 | MP0003436_decreased_susceptibility_to | 2.62405576 |
11 | MP0005360_urolithiasis | 2.60765382 |
12 | MP0003300_gastrointestinal_ulcer | 2.56211129 |
13 | MP0002419_abnormal_innate_immunity | 2.46912869 |
14 | MP0003724_increased_susceptibility_to | 2.45112550 |
15 | MP0005671_abnormal_response_to | 2.34407004 |
16 | MP0005000_abnormal_immune_tolerance | 2.24354651 |
17 | MP0002009_preneoplasia | 2.23305825 |
18 | MP0005387_immune_system_phenotype | 2.17968014 |
19 | MP0001790_abnormal_immune_system | 2.17968014 |
20 | MP0000343_altered_response_to | 2.17623926 |
21 | MP0008438_abnormal_cutaneous_collagen | 2.11075391 |
22 | MP0002254_reproductive_system_inflammat | 2.10331663 |
23 | MP0001666_abnormal_nutrient_absorption | 2.08687652 |
24 | MP0005365_abnormal_bile_salt | 2.03376967 |
25 | MP0009785_altered_susceptibility_to | 2.02782635 |
26 | MP0001533_abnormal_skeleton_physiology | 2.01078101 |
27 | MP0002998_abnormal_bone_remodeling | 1.97528381 |
28 | MP0002277_abnormal_respiratory_mucosa | 1.97082415 |
29 | MP0005025_abnormal_response_to | 1.93078322 |
30 | MP0005409_darkened_coat_color | 1.92271600 |
31 | MP0002452_abnormal_antigen_presenting | 1.89675129 |
32 | MP0001800_abnormal_humoral_immune | 1.85418731 |
33 | MP0003172_abnormal_lysosome_physiology | 1.84899939 |
34 | MP0000604_amyloidosis | 1.79990772 |
35 | MP0005464_abnormal_platelet_physiology | 1.74912027 |
36 | * MP0002723_abnormal_immune_serum | 1.70756296 |
37 | MP0001501_abnormal_sleep_pattern | 1.69424130 |
38 | MP0003690_abnormal_glial_cell | 1.69074858 |
39 | MP0001188_hyperpigmentation | 1.67837552 |
40 | MP0003252_abnormal_bile_duct | 1.66500563 |
41 | MP0009764_decreased_sensitivity_to | 1.61633471 |
42 | MP0004019_abnormal_vitamin_homeostasis | 1.61348653 |
43 | MP0004510_myositis | 1.60278148 |
44 | MP0004264_abnormal_extraembryonic_tissu | 1.57526414 |
45 | MP0005275_abnormal_skin_tensile | 1.55870998 |
46 | MP0002138_abnormal_hepatobiliary_system | 1.49584450 |
47 | MP0001958_emphysema | 1.48846075 |
48 | MP0002971_abnormal_brown_adipose | 1.47581249 |
49 | MP0002405_respiratory_system_inflammati | 1.46502507 |
50 | MP0001819_abnormal_immune_cell | 1.45853422 |
51 | MP0002796_impaired_skin_barrier | 1.45158912 |
52 | MP0008469_abnormal_protein_level | 1.44916045 |
53 | MP0002420_abnormal_adaptive_immunity | 1.44004386 |
54 | * MP0001845_abnormal_inflammatory_respons | 1.42089225 |
55 | MP0001853_heart_inflammation | 1.41456591 |
56 | MP0003075_altered_response_to | 1.41247449 |
57 | MP0005174_abnormal_tail_pigmentation | 1.40833510 |
58 | MP0002876_abnormal_thyroid_physiology | 1.39064064 |
59 | MP0003866_abnormal_defecation | 1.38268225 |
60 | MP0005310_abnormal_salivary_gland | 1.34376988 |
61 | MP0005166_decreased_susceptibility_to | 1.33477802 |
62 | MP0000538_abnormal_urinary_bladder | 1.30291378 |
63 | MP0000569_abnormal_digit_pigmentation | 1.29548305 |
64 | MP0010155_abnormal_intestine_physiology | 1.26387211 |
65 | MP0004947_skin_inflammation | 1.25370613 |
66 | MP0003448_altered_tumor_morphology | 1.23373998 |
67 | MP0000685_abnormal_immune_system | 1.22806678 |
68 | MP0004782_abnormal_surfactant_physiolog | 1.21202194 |
69 | MP0004270_analgesia | 1.20907052 |
70 | MP0005503_abnormal_tendon_morphology | 1.20848389 |
71 | MP0004043_abnormal_pH_regulation | 1.20634121 |
72 | MP0003279_aneurysm | 1.19329576 |
73 | MP0002933_joint_inflammation | 1.15753846 |
74 | MP0003705_abnormal_hypodermis_morpholog | 1.12864768 |
75 | MP0010678_abnormal_skin_adnexa | 1.11705153 |
76 | MP0005167_abnormal_blood-brain_barrier | 1.11073875 |
77 | MP0003868_abnormal_feces_composition | 1.08110517 |
78 | MP0004147_increased_porphyrin_level | 1.07059930 |
79 | MP0005390_skeleton_phenotype | 1.06041016 |
80 | MP0001542_abnormal_bone_strength | 1.06031155 |
81 | MP0000465_gastrointestinal_hemorrhage | 1.03053567 |
82 | MP0010329_abnormal_lipoprotein_level | 1.00489360 |
83 | MP0003045_fibrosis | 1.00017740 |
84 | MP0001873_stomach_inflammation | 0.95983950 |
85 | MP0003795_abnormal_bone_structure | 0.95916616 |
86 | MP0003828_pulmonary_edema | 0.93903322 |
87 | MP0003195_calcinosis | 0.93883593 |
88 | MP0002139_abnormal_hepatobiliary_system | 0.91509998 |
89 | MP0001756_abnormal_urination | 0.91407539 |
90 | MP0008875_abnormal_xenobiotic_pharmacok | 0.90445647 |
91 | MP0005164_abnormal_response_to | 0.90021816 |
92 | MP0002166_altered_tumor_susceptibility | 0.87953307 |
93 | MP0001765_abnormal_ion_homeostasis | 0.87886862 |
94 | MP0004381_abnormal_hair_follicle | 0.87631757 |
95 | MP0000716_abnormal_immune_system | 0.87617882 |
96 | MP0002136_abnormal_kidney_physiology | 0.87355635 |
97 | MP0001851_eye_inflammation | 0.86957112 |
98 | MP0002332_abnormal_exercise_endurance | 0.86749613 |
99 | MP0002909_abnormal_adrenal_gland | 0.86667594 |
100 | MP0000249_abnormal_blood_vessel | 0.82316935 |
101 | MP0005332_abnormal_amino_acid | 0.81788981 |
102 | MP0005670_abnormal_white_adipose | 0.81363584 |
103 | MP0000230_abnormal_systemic_arterial | 0.79028193 |
104 | MP0004883_abnormal_blood_vessel | 0.78834110 |
105 | MP0004484_altered_response_of | 0.78515244 |
106 | MP0009333_abnormal_splenocyte_physiolog | 0.78458723 |
107 | MP0009763_increased_sensitivity_to | 0.77469616 |
108 | MP0003763_abnormal_thymus_physiology | 0.77337387 |
109 | MP0002896_abnormal_bone_mineralization | 0.77112702 |
110 | MP0003183_abnormal_peptide_metabolism | 0.76957691 |
111 | MP0005085_abnormal_gallbladder_physiolo | 0.76956014 |
112 | MP0000767_abnormal_smooth_muscle | 0.76589465 |
113 | MP0004885_abnormal_endolymph | 0.74760762 |
114 | MP0000609_abnormal_liver_physiology | 0.74236838 |
115 | MP0002060_abnormal_skin_morphology | 0.74038668 |
116 | MP0001664_abnormal_digestion | 0.73337290 |
117 | MP0005535_abnormal_body_temperature | 0.72811741 |
118 | MP0000015_abnormal_ear_pigmentation | 0.72042194 |
119 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.71935243 |
120 | MP0005595_abnormal_vascular_smooth | 0.71636999 |
121 | MP0000462_abnormal_digestive_system | 0.71531052 |
122 | MP0002168_other_aberrant_phenotype | 0.70607074 |
123 | MP0002118_abnormal_lipid_homeostasis | 0.70224946 |
124 | MP0009115_abnormal_fat_cell | 0.70207324 |
125 | * MP0002697_abnormal_eye_size | 0.70161350 |
126 | MP0005451_abnormal_body_composition | 0.69978463 |
127 | MP0000689_abnormal_spleen_morphology | 0.69635434 |
128 | MP0002006_tumorigenesis | 0.69326989 |
129 | MP0002396_abnormal_hematopoietic_system | 0.68890498 |
130 | MP0001663_abnormal_digestive_system | 0.68697854 |
131 | * MP0005193_abnormal_anterior_eye | 0.67337685 |
132 | * MP0005197_abnormal_uvea_morphology | 0.66476397 |
133 | MP0005023_abnormal_wound_healing | 0.65453596 |
134 | * MP0009643_abnormal_urine_homeostasis | 0.65187913 |
135 | MP0005165_increased_susceptibility_to | 0.64941752 |
136 | MP0004130_abnormal_muscle_cell | 0.64912046 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Systemic lupus erythematosus (HP:0002725) | 7.43202660 |
2 | Glomerulonephritis (HP:0000099) | 5.94184079 |
3 | Complement deficiency (HP:0004431) | 5.17802356 |
4 | Nuclear cataract (HP:0100018) | 4.68406128 |
5 | Recurrent abscess formation (HP:0002722) | 4.49379392 |
6 | Eczematoid dermatitis (HP:0000976) | 4.42660197 |
7 | Recurrent bacterial skin infections (HP:0005406) | 4.39394025 |
8 | Malnutrition (HP:0004395) | 4.34628744 |
9 | Abnormality of complement system (HP:0005339) | 4.17061001 |
10 | * Zonular cataract (HP:0010920) | 4.15329991 |
11 | Vacuolated lymphocytes (HP:0001922) | 4.01260166 |
12 | Thick nail (HP:0001805) | 3.83345201 |
13 | Orchitis (HP:0100796) | 3.79312391 |
14 | Decreased circulating renin level (HP:0003351) | 3.72404172 |
15 | Optic neuritis (HP:0100653) | 3.69456957 |
16 | Retrobulbar optic neuritis (HP:0100654) | 3.69456957 |
17 | Axonal loss (HP:0003447) | 3.62372999 |
18 | Nephritis (HP:0000123) | 3.59245444 |
19 | Amelogenesis imperfecta (HP:0000705) | 3.44327984 |
20 | Myositis (HP:0100614) | 3.44298402 |
21 | Spontaneous hematomas (HP:0007420) | 3.35097015 |
22 | Autoimmune thrombocytopenia (HP:0001973) | 3.29773772 |
23 | Facial shape deformation (HP:0011334) | 3.24114216 |
24 | Potter facies (HP:0002009) | 3.24114216 |
25 | Increased cerebral lipofuscin (HP:0011813) | 3.17557268 |
26 | Prostate neoplasm (HP:0100787) | 3.17155084 |
27 | Joint hemorrhage (HP:0005261) | 3.11451644 |
28 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.11043573 |
29 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.05156202 |
30 | Disinhibition (HP:0000734) | 3.00671952 |
31 | Abnormality of T cell number (HP:0011839) | 2.95043259 |
32 | Gingivitis (HP:0000230) | 2.90160168 |
33 | Pustule (HP:0200039) | 2.84539462 |
34 | T lymphocytopenia (HP:0005403) | 2.83181522 |
35 | Abnormality of macrophages (HP:0004311) | 2.81074039 |
36 | Hematochezia (HP:0002573) | 2.80177903 |
37 | Hyperactive renin-angiotensin system (HP:0000841) | 2.78944922 |
38 | Pulmonary infiltrates (HP:0002113) | 2.75784589 |
39 | Myocardial infarction (HP:0001658) | 2.75614078 |
40 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.74896165 |
41 | Abnormality of glycolipid metabolism (HP:0010969) | 2.74896165 |
42 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.74896165 |
43 | Widely patent fontanelles and sutures (HP:0004492) | 2.70910703 |
44 | Abnormality of the prostate (HP:0008775) | 2.68514310 |
45 | Dysostosis multiplex (HP:0000943) | 2.66653242 |
46 | Recurrent skin infections (HP:0001581) | 2.64563237 |
47 | Abnormality of vitamin B metabolism (HP:0004340) | 2.64202743 |
48 | Congenital sensorineural hearing impairment (HP:0008527) | 2.60333927 |
49 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.59420920 |
50 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.56540287 |
51 | Obstructive lung disease (HP:0006536) | 2.55390628 |
52 | Chronic obstructive pulmonary disease (HP:0006510) | 2.55390628 |
53 | Chronic diarrhea (HP:0002028) | 2.54293512 |
54 | Keratoconjunctivitis sicca (HP:0001097) | 2.48770176 |
55 | Hydroxyprolinuria (HP:0003080) | 2.47848934 |
56 | Abnormality of proline metabolism (HP:0010907) | 2.47848934 |
57 | Thickened helices (HP:0000391) | 2.47406859 |
58 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.47142978 |
59 | Aplasia cutis congenita (HP:0001057) | 2.41023174 |
60 | Pathologic fracture (HP:0002756) | 2.39601340 |
61 | Arterial tortuosity (HP:0005116) | 2.33576230 |
62 | Abnormality of incisor morphology (HP:0011063) | 2.31666664 |
63 | Increased IgE level (HP:0003212) | 2.26861261 |
64 | Mediastinal lymphadenopathy (HP:0100721) | 2.26257646 |
65 | Keratoconjunctivitis (HP:0001096) | 2.25407965 |
66 | Arterial thrombosis (HP:0004420) | 2.25068633 |
67 | Palmoplantar hyperkeratosis (HP:0000972) | 2.24953037 |
68 | Recurrent fungal infections (HP:0002841) | 2.24643300 |
69 | Bone pain (HP:0002653) | 2.22929138 |
70 | Hemoptysis (HP:0002105) | 2.22521401 |
71 | Eosinophilia (HP:0001880) | 2.20576774 |
72 | Osteolytic defects of the hand bones (HP:0009699) | 2.19154022 |
73 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.19154022 |
74 | Protuberant abdomen (HP:0001538) | 2.18507760 |
75 | Hyperkalemia (HP:0002153) | 2.17956558 |
76 | Pulmonary embolism (HP:0002204) | 2.16033172 |
77 | Upper motor neuron abnormality (HP:0002127) | 2.15186098 |
78 | Abnormality of renin-angiotensin system (HP:0000847) | 2.15119366 |
79 | Fat malabsorption (HP:0002630) | 2.14328939 |
80 | Stomatitis (HP:0010280) | 2.13469343 |
81 | Periodontitis (HP:0000704) | 2.12701801 |
82 | Vasculitis (HP:0002633) | 2.11052228 |
83 | Thyroiditis (HP:0100646) | 2.10342254 |
84 | Increased CSF protein (HP:0002922) | 2.10264613 |
85 | Palmar hyperkeratosis (HP:0010765) | 2.09607392 |
86 | Vascular tortuosity (HP:0004948) | 2.07398056 |
87 | Joint swelling (HP:0001386) | 2.05577574 |
88 | Basal ganglia calcification (HP:0002135) | 2.04585189 |
89 | Frequent falls (HP:0002359) | 2.04117391 |
90 | Exercise-induced myalgia (HP:0003738) | 2.02772923 |
91 | Alopecia of scalp (HP:0002293) | 2.00279168 |
92 | Hypobetalipoproteinemia (HP:0003563) | 1.99932033 |
93 | Urethral obstruction (HP:0000796) | 1.99238090 |
94 | Premature loss of primary teeth (HP:0006323) | 1.97704237 |
95 | Retinal atrophy (HP:0001105) | 1.97372007 |
96 | Aortic dissection (HP:0002647) | 1.95542958 |
97 | Xanthomatosis (HP:0000991) | 1.95235973 |
98 | Peripheral demyelination (HP:0011096) | 1.94244536 |
99 | Mucopolysacchariduria (HP:0008155) | 1.94043628 |
100 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.94043628 |
101 | Gangrene (HP:0100758) | 1.92929433 |
102 | Neonatal short-limb short stature (HP:0008921) | 1.92656806 |
103 | * Corneal dystrophy (HP:0001131) | 1.92077694 |
104 | Progressive visual loss (HP:0000529) | 1.92019611 |
105 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.88756699 |
106 | Metabolic alkalosis (HP:0200114) | 1.88130288 |
107 | Abnormality of vitamin metabolism (HP:0100508) | 1.87243605 |
108 | Plantar hyperkeratosis (HP:0007556) | 1.86158343 |
109 | Atrophic scars (HP:0001075) | 1.85996613 |
110 | Patchy hypopigmentation of hair (HP:0011365) | 1.85960276 |
111 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.85916443 |
112 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.85916443 |
113 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.85916443 |
114 | Stomach cancer (HP:0012126) | 1.80802026 |
115 | Abnormality of the lumbar spine (HP:0100712) | 1.80619241 |
116 | Arthropathy (HP:0003040) | 1.80520353 |
117 | Conjunctival hamartoma (HP:0100780) | 1.80284304 |
118 | Hypokalemia (HP:0002900) | 1.79830209 |
119 | Abnormality of T cells (HP:0002843) | 1.79046366 |
120 | Inflammation of the large intestine (HP:0002037) | 1.78868285 |
121 | Bone cyst (HP:0012062) | 1.78856649 |
122 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.78727253 |
123 | Conical tooth (HP:0000698) | 1.78543298 |
124 | Agnosia (HP:0010524) | 1.78451038 |
125 | Meningitis (HP:0001287) | 1.78180030 |
126 | Hypotension (HP:0002615) | 1.77297484 |
127 | Epistaxis (HP:0000421) | 1.77249648 |
128 | Leukocytosis (HP:0001974) | 1.76564108 |
129 | Hyperventilation (HP:0002883) | 1.76120430 |
130 | Osteomyelitis (HP:0002754) | 1.75386803 |
131 | Abdominal distention (HP:0003270) | 1.74649005 |
132 | Gingival bleeding (HP:0000225) | 1.74645438 |
133 | Epidermoid cyst (HP:0200040) | 1.74362120 |
134 | Glomerulopathy (HP:0100820) | 1.73953383 |
135 | Thrombophlebitis (HP:0004418) | 1.73615576 |
136 | Confusion (HP:0001289) | 1.73584120 |
137 | Abnormality of the axillary hair (HP:0100134) | 1.73008540 |
138 | Abnormality of secondary sexual hair (HP:0009888) | 1.73008540 |
139 | Milia (HP:0001056) | 1.72902390 |
140 | Chest pain (HP:0100749) | 1.72767993 |
141 | Abnormality of the pericardium (HP:0001697) | 1.72615934 |
142 | Acanthocytosis (HP:0001927) | 1.71849306 |
143 | Alkalosis (HP:0001948) | 1.71629132 |
144 | Steatorrhea (HP:0002570) | 1.70432547 |
145 | Abnormality of potassium homeostasis (HP:0011042) | 1.70407590 |
146 | Spondylolisthesis (HP:0003302) | 1.70302290 |
147 | Asymmetric septal hypertrophy (HP:0001670) | 1.70120533 |
148 | White forelock (HP:0002211) | 1.69701836 |
149 | Mutism (HP:0002300) | 1.68703752 |
150 | Proximal tubulopathy (HP:0000114) | 1.68582493 |
151 | Hypotrichosis (HP:0001006) | 1.68537681 |
152 | Abnormality of the costochondral junction (HP:0000919) | 1.66520917 |
153 | Autoimmune hemolytic anemia (HP:0001890) | 1.65132294 |
154 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.63362433 |
155 | Recurrent bronchitis (HP:0002837) | 1.61474519 |
156 | Recurrent cutaneous fungal infections (HP:0011370) | 1.60632046 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TXK | 4.91657357 |
2 | ACVR1B | 4.46924603 |
3 | TGFBR2 | 4.30747675 |
4 | BLK | 3.74937040 |
5 | MAP3K14 | 3.71186342 |
6 | TYK2 | 3.09111188 |
7 | GRK7 | 2.66872325 |
8 | MST4 | 2.61753369 |
9 | NEK9 | 2.43577556 |
10 | IRAK3 | 2.32924605 |
11 | EPHA3 | 2.04995398 |
12 | TNIK | 1.99866252 |
13 | JAK1 | 1.97504509 |
14 | IRAK4 | 1.89417878 |
15 | STK24 | 1.84407867 |
16 | RIPK1 | 1.82509697 |
17 | FGFR2 | 1.76022822 |
18 | TBK1 | 1.69749969 |
19 | IKBKE | 1.60814259 |
20 | OBSCN | 1.57893763 |
21 | NLK | 1.57782936 |
22 | MAP3K13 | 1.41431483 |
23 | PIK3CG | 1.37781340 |
24 | KIT | 1.34063453 |
25 | CSF1R | 1.33256268 |
26 | MAP4K1 | 1.32722937 |
27 | JAK3 | 1.32651641 |
28 | IKBKB | 1.26788861 |
29 | STK10 | 1.26568652 |
30 | ZAP70 | 1.25900198 |
31 | HCK | 1.24849797 |
32 | NUAK1 | 1.21894100 |
33 | JAK2 | 1.21608974 |
34 | FGFR4 | 1.17724745 |
35 | MAPKAPK3 | 1.10724757 |
36 | FGFR3 | 1.09297770 |
37 | MAP3K10 | 1.09238073 |
38 | RIPK4 | 1.08691417 |
39 | CLK1 | 1.07062538 |
40 | ITK | 1.05344370 |
41 | LCK | 1.05286385 |
42 | EPHB1 | 1.04120413 |
43 | AKT3 | 1.03519542 |
44 | YES1 | 0.98928886 |
45 | GRK6 | 0.97492824 |
46 | CSK | 0.97197708 |
47 | MAP2K6 | 0.96854166 |
48 | PIM2 | 0.96756192 |
49 | PINK1 | 0.95431357 |
50 | CAMK1G | 0.93953905 |
51 | BMPR2 | 0.92902412 |
52 | DMPK | 0.92873683 |
53 | ERN1 | 0.92583330 |
54 | LYN | 0.91314216 |
55 | CDK6 | 0.91107577 |
56 | PRPF4B | 0.90719587 |
57 | STK39 | 0.89859046 |
58 | SGK494 | 0.88553825 |
59 | SGK223 | 0.88553825 |
60 | CHUK | 0.88042586 |
61 | CAMKK2 | 0.87476931 |
62 | TNK2 | 0.84910491 |
63 | OXSR1 | 0.84766447 |
64 | MAP3K2 | 0.82442493 |
65 | FES | 0.81801300 |
66 | EIF2AK2 | 0.81678149 |
67 | MST1R | 0.80392943 |
68 | MAPK12 | 0.79652880 |
69 | MAPK11 | 0.79035330 |
70 | SYK | 0.78992796 |
71 | CAMK1D | 0.78603084 |
72 | MARK1 | 0.77870711 |
73 | IGF1R | 0.76536083 |
74 | TAOK3 | 0.74888697 |
75 | TTN | 0.72563897 |
76 | BTK | 0.72023324 |
77 | PHKG2 | 0.69116799 |
78 | PHKG1 | 0.69116799 |
79 | TEC | 0.68074886 |
80 | CASK | 0.67036645 |
81 | ERBB2 | 0.66972558 |
82 | TYRO3 | 0.65914774 |
83 | MAP3K7 | 0.65485691 |
84 | NTRK1 | 0.65340637 |
85 | TGFBR1 | 0.64611330 |
86 | TRPM7 | 0.64022074 |
87 | SIK3 | 0.62945010 |
88 | ADRBK2 | 0.62484487 |
89 | SGK3 | 0.61915313 |
90 | PKN1 | 0.60910540 |
91 | SGK2 | 0.59238478 |
92 | PRKCQ | 0.58975203 |
93 | MAP3K1 | 0.57241330 |
94 | MATK | 0.57100709 |
95 | MAPK7 | 0.56157364 |
96 | MOS | 0.55840924 |
97 | RPS6KA2 | 0.55211570 |
98 | PDK2 | 0.54944453 |
99 | PDK1 | 0.54759420 |
100 | FGR | 0.54029917 |
101 | LATS1 | 0.53502257 |
102 | PDGFRB | 0.53327258 |
103 | PRKG1 | 0.53278189 |
104 | WNK3 | 0.52642997 |
105 | MAPK13 | 0.52167781 |
106 | GRK5 | 0.51670986 |
107 | PBK | 0.51618920 |
108 | IRAK1 | 0.51277966 |
109 | NTRK2 | 0.51260117 |
110 | MAP3K3 | 0.50808231 |
111 | BMPR1B | 0.50493913 |
112 | RPS6KL1 | 0.50223852 |
113 | RPS6KC1 | 0.50223852 |
114 | BMX | 0.50085501 |
115 | PRKG2 | 0.49348007 |
116 | BCR | 0.48930880 |
117 | RPS6KA6 | 0.48763466 |
118 | ERBB3 | 0.48583152 |
119 | CDK3 | 0.48156382 |
120 | PRKCE | 0.47821867 |
121 | PTK6 | 0.47277926 |
122 | PRKCD | 0.46837512 |
123 | EPHA4 | 0.46718908 |
124 | FGFR1 | 0.46606420 |
125 | INSR | 0.46522340 |
126 | STK3 | 0.46070460 |
127 | FYN | 0.46052485 |
128 | PIM1 | 0.45483667 |
129 | PRKAA2 | 0.44893425 |
130 | MAPKAPK2 | 0.44468317 |
131 | PIK3CA | 0.43403503 |
132 | GSK3A | 0.43263769 |
133 | FER | 0.43073335 |
134 | RPS6KB1 | 0.42951875 |
135 | PRKACG | 0.42391607 |
136 | RET | 0.42114407 |
137 | WNK1 | 0.41094363 |
138 | FRK | 0.40604483 |
139 | SGK1 | 0.40466003 |
140 | ROCK1 | 0.40421521 |
141 | EGFR | 0.40163244 |
142 | STK11 | 0.39909813 |
143 | MARK3 | 0.39881894 |
144 | EPHB2 | 0.39221442 |
145 | CDK8 | 0.39137299 |
146 | ABL1 | 0.38313685 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 5.01214833 |
2 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.35693009 |
3 | Other glycan degradation_Homo sapiens_hsa00511 | 2.23481189 |
4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.22592427 |
5 | Lysosome_Homo sapiens_hsa04142 | 2.20344453 |
6 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.10780892 |
7 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.99602918 |
8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.99157727 |
9 | * Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.98967311 |
10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.97287538 |
11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.86388485 |
12 | Pertussis_Homo sapiens_hsa05133 | 1.84611870 |
13 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.82909453 |
14 | Allograft rejection_Homo sapiens_hsa05330 | 1.76449082 |
15 | Asthma_Homo sapiens_hsa05310 | 1.75792802 |
16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.64157047 |
17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.64039252 |
18 | Tuberculosis_Homo sapiens_hsa05152 | 1.63891606 |
19 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.57814464 |
20 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.55534929 |
21 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.53991722 |
22 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.51127632 |
23 | Measles_Homo sapiens_hsa05162 | 1.50194686 |
24 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.48087417 |
25 | Mineral absorption_Homo sapiens_hsa04978 | 1.45491375 |
26 | Phagosome_Homo sapiens_hsa04145 | 1.42254844 |
27 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.41618356 |
28 | Malaria_Homo sapiens_hsa05144 | 1.36814095 |
29 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.35300651 |
30 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.33074707 |
31 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.32985018 |
32 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.17507217 |
33 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.16851011 |
34 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.14426476 |
35 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.13903849 |
36 | Salmonella infection_Homo sapiens_hsa05132 | 1.12961274 |
37 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.12947362 |
38 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.12509511 |
39 | Legionellosis_Homo sapiens_hsa05134 | 1.12357450 |
40 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.09449090 |
41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.07227467 |
42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.97647152 |
43 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.96734803 |
44 | Prion diseases_Homo sapiens_hsa05020 | 0.96260236 |
45 | Circadian rhythm_Homo sapiens_hsa04710 | 0.95833253 |
46 | Influenza A_Homo sapiens_hsa05164 | 0.94694763 |
47 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.94048605 |
48 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.93884574 |
49 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.90905801 |
50 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.89493661 |
51 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.89206205 |
52 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.89161462 |
53 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.87455968 |
54 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.86333299 |
55 | Amoebiasis_Homo sapiens_hsa05146 | 0.84978270 |
56 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.84762339 |
57 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.82576476 |
58 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.82339765 |
59 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.81056718 |
60 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.79941062 |
61 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.78972920 |
62 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.78223532 |
63 | ABC transporters_Homo sapiens_hsa02010 | 0.74842960 |
64 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.73435983 |
65 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.72553056 |
66 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.72463219 |
67 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.71706260 |
68 | Galactose metabolism_Homo sapiens_hsa00052 | 0.69901265 |
69 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.68934082 |
70 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.67929617 |
71 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.66991078 |
72 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.66285777 |
73 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.65626338 |
74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.65371881 |
75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65244047 |
76 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.64892734 |
77 | Hepatitis C_Homo sapiens_hsa05160 | 0.64654975 |
78 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.64448968 |
79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.64360202 |
80 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.64219091 |
81 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.64189039 |
82 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.64135168 |
83 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.64033085 |
84 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.63893927 |
85 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.63243522 |
86 | Viral myocarditis_Homo sapiens_hsa05416 | 0.60322820 |
87 | Insulin resistance_Homo sapiens_hsa04931 | 0.59249567 |
88 | Histidine metabolism_Homo sapiens_hsa00340 | 0.58682604 |
89 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.58461605 |
90 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.57727760 |
91 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.57512238 |
92 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.57030672 |
93 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.56424091 |
94 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.55769936 |
95 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.55458827 |
96 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.55259332 |
97 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.54550573 |
98 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.53020719 |
99 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.52452191 |
100 | Platelet activation_Homo sapiens_hsa04611 | 0.52242217 |
101 | Apoptosis_Homo sapiens_hsa04210 | 0.52190994 |
102 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51944375 |
103 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.51263236 |
104 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.50631157 |
105 | Peroxisome_Homo sapiens_hsa04146 | 0.50426453 |
106 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.50335228 |
107 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50158663 |
108 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.50066737 |
109 | Endocytosis_Homo sapiens_hsa04144 | 0.49197556 |
110 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.47306862 |
111 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.47232690 |
112 | Long-term potentiation_Homo sapiens_hsa04720 | 0.47146948 |
113 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.46880692 |
114 | Insulin secretion_Homo sapiens_hsa04911 | 0.44950329 |
115 | Adherens junction_Homo sapiens_hsa04520 | 0.44845193 |
116 | Hepatitis B_Homo sapiens_hsa05161 | 0.44248221 |
117 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.42668211 |
118 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.41481811 |
119 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.38271044 |
120 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.37998312 |
121 | Focal adhesion_Homo sapiens_hsa04510 | 0.37142807 |
122 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.36884085 |
123 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.36468557 |
124 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.36104722 |
125 | Long-term depression_Homo sapiens_hsa04730 | 0.35692350 |
126 | Shigellosis_Homo sapiens_hsa05131 | 0.34534897 |
127 | Bile secretion_Homo sapiens_hsa04976 | 0.34490668 |
128 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.33525011 |
129 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.33246942 |
130 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.33203928 |
131 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.33114748 |
132 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.32769539 |
133 | Renin secretion_Homo sapiens_hsa04924 | 0.32270051 |
134 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.31684472 |