MAGEB16

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synapsis (GO:0007129)8.77055010
2male meiosis (GO:0007140)8.33155842
3meiosis I (GO:0007127)8.07860438
4resolution of meiotic recombination intermediates (GO:0000712)7.68268402
5gene silencing by RNA (GO:0031047)7.26085424
6meiotic cell cycle process (GO:1903046)5.89505989
7DNA synthesis involved in DNA repair (GO:0000731)5.82010575
8regulation of histone H3-K9 methylation (GO:0051570)5.73618545
9positive regulation of meiosis (GO:0045836)5.71421331
10meiotic cell cycle (GO:0051321)5.54485007
11positive regulation of meiotic cell cycle (GO:0051446)5.39769519
12sex differentiation (GO:0007548)5.08761547
13sister chromatid cohesion (GO:0007062)4.86802345
14ribosome assembly (GO:0042255)4.86111159
15purine nucleobase biosynthetic process (GO:0009113)4.80438190
16mitotic metaphase plate congression (GO:0007080)4.76081137
17nucleobase biosynthetic process (GO:0046112)4.74862518
18DNA methylation (GO:0006306)4.72499358
19DNA alkylation (GO:0006305)4.72499358
20centriole assembly (GO:0098534)4.65031829
21DNA replication checkpoint (GO:0000076)4.53720671
22mitotic sister chromatid cohesion (GO:0007064)4.48913222
23nuclear pore organization (GO:0006999)4.41817637
24DNA replication initiation (GO:0006270)4.41500332
25DNA replication-dependent nucleosome assembly (GO:0006335)4.36601435
26DNA replication-dependent nucleosome organization (GO:0034723)4.36601435
27formation of translation preinitiation complex (GO:0001731)4.28025952
28regulation of gene silencing by RNA (GO:0060966)4.19156721
29regulation of posttranscriptional gene silencing (GO:0060147)4.19156721
30regulation of gene silencing by miRNA (GO:0060964)4.19156721
31mesenchyme development (GO:0060485)4.16471122
32ribosome biogenesis (GO:0042254)4.16018010
33gene silencing (GO:0016458)4.12206342
34nuclear pore complex assembly (GO:0051292)4.10710415
35ncRNA 3-end processing (GO:0043628)4.07821386
36maturation of SSU-rRNA (GO:0030490)4.02707733
37metaphase plate congression (GO:0051310)4.00607876
38DNA strand elongation involved in DNA replication (GO:0006271)4.00544740
39mitotic nuclear envelope disassembly (GO:0007077)4.00074361
40protein localization to kinetochore (GO:0034501)3.99307168
41piRNA metabolic process (GO:0034587)3.98078435
42oogenesis (GO:0048477)3.87753436
43positive regulation of translational initiation (GO:0045948)3.81041920
44regulation of helicase activity (GO:0051095)3.80206273
45synaptonemal complex assembly (GO:0007130)3.79122071
46DNA strand elongation (GO:0022616)3.78124713
47protein K6-linked ubiquitination (GO:0085020)3.77476271
48histone H3-K9 demethylation (GO:0033169)3.76313834
49mesoderm development (GO:0007498)3.75890546
50membrane disassembly (GO:0030397)3.73564089
51nuclear envelope disassembly (GO:0051081)3.73564089
52folic acid transport (GO:0015884)3.73376608
53chromatin remodeling at centromere (GO:0031055)3.72248287
54nucleotide transmembrane transport (GO:1901679)3.71544320
55somatic diversification of immune receptors via somatic mutation (GO:0002566)3.66074842
56somatic hypermutation of immunoglobulin genes (GO:0016446)3.66074842
57telomere maintenance via semi-conservative replication (GO:0032201)3.63322689
58proline biosynthetic process (GO:0006561)3.61349987
59rRNA modification (GO:0000154)3.58610956
60folic acid metabolic process (GO:0046655)3.58033082
61regulation of histone methylation (GO:0031060)3.55765460
62CENP-A containing nucleosome assembly (GO:0034080)3.54831982
63proteasome assembly (GO:0043248)3.54706123
64regulation of nuclear cell cycle DNA replication (GO:0033262)3.53805055
65attachment of spindle microtubules to kinetochore (GO:0008608)3.53190240
66female gamete generation (GO:0007292)3.52895482
67DNA methylation or demethylation (GO:0044728)3.52008585
68ribonucleoprotein complex biogenesis (GO:0022613)3.51559889
69IMP biosynthetic process (GO:0006188)3.50487891
70regulation of DNA endoreduplication (GO:0032875)3.45452298
71regulation of spindle organization (GO:0090224)3.45066569
72positive regulation of chromosome segregation (GO:0051984)3.43450144
73DNA replication-independent nucleosome organization (GO:0034724)3.42253251
74DNA replication-independent nucleosome assembly (GO:0006336)3.42253251
75establishment of chromosome localization (GO:0051303)3.40910703
76kinetochore organization (GO:0051383)3.40037657
77regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.39471348
78telomere maintenance via recombination (GO:0000722)3.36179849
79synaptonemal complex organization (GO:0070193)3.36179100
80negative regulation of chromosome segregation (GO:0051985)3.35295536
81anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.33078602
82histone exchange (GO:0043486)3.32005730
83DNA unwinding involved in DNA replication (GO:0006268)3.31406745
84folic acid-containing compound biosynthetic process (GO:0009396)3.31239153
85kinetochore assembly (GO:0051382)3.30817952
86DNA methylation involved in gamete generation (GO:0043046)3.30510212
87negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.30411407
88negative regulation of sister chromatid segregation (GO:0033046)3.30411407
89negative regulation of mitotic sister chromatid separation (GO:2000816)3.30411407
90negative regulation of mitotic sister chromatid segregation (GO:0033048)3.30411407
91spindle checkpoint (GO:0031577)3.29835841
92protein localization to chromosome, centromeric region (GO:0071459)3.29508587
93regulation of meiosis (GO:0040020)3.26799504
94regulation of centrosome cycle (GO:0046605)3.26324582
95mitotic spindle checkpoint (GO:0071174)3.25609255
96regulation of chromosome segregation (GO:0051983)3.25075056
97pore complex assembly (GO:0046931)3.24656249
98mitotic recombination (GO:0006312)3.24471764
99mitotic spindle assembly checkpoint (GO:0007094)3.23937243
100regulation of double-strand break repair via homologous recombination (GO:0010569)3.23636731
101telomere maintenance via telomere lengthening (GO:0010833)3.23262573
102mitotic sister chromatid segregation (GO:0000070)3.22128490
103regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.21853901
104spindle assembly checkpoint (GO:0071173)3.21659101
105negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.21501828
106positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.20298854
107meiotic chromosome segregation (GO:0045132)3.20244305
108pyrimidine dimer repair (GO:0006290)3.19922735
109rRNA processing (GO:0006364)3.19492483
110regulation of mitotic metaphase/anaphase transition (GO:0030071)3.19437547
111mitotic chromosome condensation (GO:0007076)3.19273957
112reciprocal DNA recombination (GO:0035825)3.17751710
113reciprocal meiotic recombination (GO:0007131)3.17751710
114regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.16518086
115regulation of meiotic cell cycle (GO:0051445)3.16282689
116histone H4-K12 acetylation (GO:0043983)3.15837197
117regulation of meiosis I (GO:0060631)3.14591750
118spliceosomal snRNP assembly (GO:0000387)3.13939288
119ribosomal large subunit biogenesis (GO:0042273)3.13914982
120negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.13375064
121regulation of centriole replication (GO:0046599)3.13362012
122regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.12802278
123meiotic nuclear division (GO:0007126)3.10805775
124transcription-coupled nucleotide-excision repair (GO:0006283)3.10067824
125regulation of telomere maintenance via telomerase (GO:0032210)3.09932344
126chaperone-mediated protein complex assembly (GO:0051131)3.09531149
127lymphangiogenesis (GO:0001946)3.09451382
128rRNA metabolic process (GO:0016072)3.09302090
129chromosome organization involved in meiosis (GO:0070192)3.08792042
130transcription from RNA polymerase I promoter (GO:0006360)3.08033565
131maturation of 5.8S rRNA (GO:0000460)3.07307949
132regulation of mitotic spindle organization (GO:0060236)3.06979144
133regulation of mitotic sister chromatid separation (GO:0010965)3.06375341
134regulation of mitotic sister chromatid segregation (GO:0033047)3.06375341
135regulation of sister chromatid segregation (GO:0033045)3.06375341
136centriole replication (GO:0007099)3.05873007
137nucleosome assembly (GO:0006334)3.01952288
138gonadal mesoderm development (GO:0007506)24.0615443
139oocyte maturation (GO:0001556)2.98064609
140motile cilium assembly (GO:0044458)2.96595623
141male gamete generation (GO:0048232)2.93066358
142spermatogenesis (GO:0007283)2.92014519
143DNA modification (GO:0006304)2.88709827
144embryonic body morphogenesis (GO:0010172)2.82620329
145gamete generation (GO:0007276)2.81120850
146positive regulation of histone methylation (GO:0031062)2.79147970
147nucleosome organization (GO:0034728)2.75592521
148cilium or flagellum-dependent cell motility (GO:0001539)2.75095386
149protein localization to chromosome (GO:0034502)2.74357712
150protein-DNA complex assembly (GO:0065004)2.71115181
151chromosome organization (GO:0051276)2.67373177
152nucleus organization (GO:0006997)2.62516863
153binding of sperm to zona pellucida (GO:0007339)2.62364118
154nuclear division (GO:0000280)2.59156259
155proline metabolic process (GO:0006560)2.58906788
156histone H2A acetylation (GO:0043968)2.58214774
157poly(A)+ mRNA export from nucleus (GO:0016973)2.58210494
158regulation of mitochondrial translation (GO:0070129)2.57180584
159nucleotide-excision repair, DNA gap filling (GO:0006297)2.56700081
160negative regulation of gene silencing (GO:0060969)2.56010158
161protein-DNA complex subunit organization (GO:0071824)2.53323670
162mismatch repair (GO:0006298)2.50764803
163DNA biosynthetic process (GO:0071897)2.47372128
164ribosomal small subunit assembly (GO:0000028)2.45891028
165DNA catabolic process, exonucleolytic (GO:0000738)2.44855332
166organelle fission (GO:0048285)2.44492550
167fertilization (GO:0009566)2.41981495
168regulation of histone H3-K4 methylation (GO:0051569)2.41741537
169germ cell development (GO:0007281)2.38740738
170regulation of protein polyubiquitination (GO:1902914)2.38073498
171embryonic foregut morphogenesis (GO:0048617)2.33738828
172snRNA transcription (GO:0009301)2.33315179
173male meiosis I (GO:0007141)10.1916706

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.93241821
2IGF1R_20145208_ChIP-Seq_DFB_Human4.34427609
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.21190264
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.79075119
5FOXM1_23109430_ChIP-Seq_U2OS_Human3.56770267
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.33789809
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.25464172
8EZH2_22144423_ChIP-Seq_EOC_Human3.17058326
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.95168773
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.91702685
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.88720379
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.87738237
13MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.78012126
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.75580938
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.73688799
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.71293054
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.70961899
18ZNF274_21170338_ChIP-Seq_K562_Hela2.70366369
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.69379598
20KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.67608693
21KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.67608693
22KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.67608693
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.56397518
24GABP_17652178_ChIP-ChIP_JURKAT_Human2.51572220
25NANOG_18555785_ChIP-Seq_MESCs_Mouse2.50559121
26POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.44204718
27CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.43396106
28SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.42266219
29NELFA_20434984_ChIP-Seq_ESCs_Mouse2.42172091
30KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.28438297
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.21325541
32MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.20041017
33NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.13151148
34NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.11773967
35HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.11669097
36AR_21909140_ChIP-Seq_LNCAP_Human2.09687336
37E2F1_18555785_ChIP-Seq_MESCs_Mouse2.06337116
38XRN2_22483619_ChIP-Seq_HELA_Human2.04185015
39SALL1_21062744_ChIP-ChIP_HESCs_Human2.03086973
40PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.02547029
41MYCN_18555785_ChIP-Seq_MESCs_Mouse2.01165550
42STAT3_1855785_ChIP-Seq_MESCs_Mouse1.94935445
43NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.93230849
44VDR_23849224_ChIP-Seq_CD4+_Human1.92716126
45POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.87708475
46TAF15_26573619_Chip-Seq_HEK293_Human1.83106637
47TCF3_18692474_ChIP-Seq_MEFs_Mouse1.78190135
48THAP11_20581084_ChIP-Seq_MESCs_Mouse1.73865270
49YY1_21170310_ChIP-Seq_MESCs_Mouse1.73111555
50E2F1_21310950_ChIP-Seq_MCF-7_Human1.72254159
51DCP1A_22483619_ChIP-Seq_HELA_Human1.70401713
52SOX2_18555785_ChIP-Seq_MESCs_Mouse1.65775313
53YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.60194180
54GABP_19822575_ChIP-Seq_HepG2_Human1.59317371
55ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.57682167
56NOTCH1_21737748_ChIP-Seq_TLL_Human1.57513071
57FOXP3_21729870_ChIP-Seq_TREG_Human1.56946146
58GATA1_26923725_Chip-Seq_HPCs_Mouse1.56273132
59HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.55988451
60TTF2_22483619_ChIP-Seq_HELA_Human1.52896814
61PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52789006
62NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.51153075
63TCF3_18692474_ChIP-Seq_MESCs_Mouse1.50685279
64TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.48273103
65GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45231254
66SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.44555646
67PKCTHETA_26484144_Chip-Seq_BREAST_Human1.43582697
68HOXB4_20404135_ChIP-ChIP_EML_Mouse1.43180856
69CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41069387
70MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.39958054
71RNF2_27304074_Chip-Seq_NSC_Mouse1.39604483
72ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.37817439
73EGR1_19374776_ChIP-ChIP_THP-1_Human1.37606373
74KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.37442110
75RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.37190654
76KLF4_18555785_ChIP-Seq_MESCs_Mouse1.35609659
77ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35146230
78KDM5A_27292631_Chip-Seq_BREAST_Human1.35137842
79NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.30209137
80ELK1_19687146_ChIP-ChIP_HELA_Human1.29990068
81SOX2_18692474_ChIP-Seq_MEFs_Mouse1.29952303
82VDR_22108803_ChIP-Seq_LS180_Human1.27935451
83ESR1_15608294_ChIP-ChIP_MCF-7_Human1.23291192
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.22712757
85SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.22454304
86SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.22172698
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20328644
88NANOG_18692474_ChIP-Seq_MEFs_Mouse1.20116544
89NANOG_21062744_ChIP-ChIP_HESCs_Human1.19855514
90POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19763911
91ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.16140032
92OCT4_18692474_ChIP-Seq_MEFs_Mouse1.15886217
93PADI4_21655091_ChIP-ChIP_MCF-7_Human1.14704990
94SOX2_18692474_ChIP-Seq_MESCs_Mouse1.14285557
95FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.11313815
96MYC_18940864_ChIP-ChIP_HL60_Human1.10423417
97SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.09893752
98CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.09816429
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.08736575
100ER_23166858_ChIP-Seq_MCF-7_Human1.08143985
101RBPJ_22232070_ChIP-Seq_NCS_Mouse1.07949892
102SRF_21415370_ChIP-Seq_HL-1_Mouse1.07036208
103POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.05401579
104NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.05165261
105TBX5_21415370_ChIP-Seq_HL-1_Mouse1.04833357
106CIITA_25753668_ChIP-Seq_RAJI_Human1.04154079
107TFEB_21752829_ChIP-Seq_HELA_Human1.04137663
108NANOG_18692474_ChIP-Seq_MESCs_Mouse1.03393037
109ELF1_17652178_ChIP-ChIP_JURKAT_Human1.03325383
110POU5F1_16518401_ChIP-PET_MESCs_Mouse1.03066335
111EWS_26573619_Chip-Seq_HEK293_Human1.01005101
112CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.00857815
113ERG_20887958_ChIP-Seq_HPC-7_Mouse0.98888449
114CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.98401734
115SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.98255265
116TP63_19390658_ChIP-ChIP_HaCaT_Human0.97684618
117FOXA1_21572438_ChIP-Seq_LNCaP_Human0.97479575
118GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.96995460
119RUNX1_26923725_Chip-Seq_HPCs_Mouse0.94581412
120KAP1_27257070_Chip-Seq_ESCs_Mouse0.94341405
121FOXA1_27270436_Chip-Seq_PROSTATE_Human0.93688569
122FOXA1_25329375_ChIP-Seq_VCAP_Human0.93688569
123CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93372795
124FUS_26573619_Chip-Seq_HEK293_Human0.93154204
125SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.92807524
126* RUNX2_22187159_ChIP-Seq_PCA_Human0.92547977
127PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92450310
128DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.90493951
129BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.90386387
130E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.90160386
131TP53_22573176_ChIP-Seq_HFKS_Human0.89391610
132KAP1_22055183_ChIP-Seq_ESCs_Mouse0.87806618
133SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.86215853
134FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.86112410
135SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.86030359
136HTT_18923047_ChIP-ChIP_STHdh_Human0.82929347
137STAT3_23295773_ChIP-Seq_U87_Human0.80957061
138SOX2_16153702_ChIP-ChIP_HESCs_Human0.79564434
139TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.78231927
140E2F1_17053090_ChIP-ChIP_MCF-7_Human0.76665260
141SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.75535329
142TOP2B_26459242_ChIP-Seq_MCF-7_Human0.74599319
143IRF1_19129219_ChIP-ChIP_H3396_Human0.74448908

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.54804213
2MP0010368_abnormal_lymphatic_system5.01233350
3MP0003111_abnormal_nucleus_morphology4.70034883
4MP0004957_abnormal_blastocyst_morpholog4.65884328
5MP0010094_abnormal_chromosome_stability4.53798289
6MP0008057_abnormal_DNA_replication4.09126256
7MP0003077_abnormal_cell_cycle3.83974286
8MP0008877_abnormal_DNA_methylation3.66761520
9MP0008058_abnormal_DNA_repair3.64937467
10MP0003806_abnormal_nucleotide_metabolis3.19170512
11MP0003123_paternal_imprinting3.08043290
12MP0003718_maternal_effect2.74285448
13MP0008932_abnormal_embryonic_tissue2.71648333
14MP0003786_premature_aging2.70102048
15MP0001730_embryonic_growth_arrest2.57673101
16MP0000350_abnormal_cell_proliferation2.24809614
17MP0008007_abnormal_cellular_replicative2.24578230
18MP0010352_gastrointestinal_tract_polyps2.23371309
19MP0002210_abnormal_sex_determination2.08496627
20MP0003941_abnormal_skin_development2.05240157
21MP0005174_abnormal_tail_pigmentation1.93485892
22MP0001672_abnormal_embryogenesis/_devel1.91404443
23MP0005380_embryogenesis_phenotype1.91404443
24MP0010307_abnormal_tumor_latency1.82708502
25MP0001145_abnormal_male_reproductive1.82351583
26MP0002653_abnormal_ependyma_morphology1.78428945
27MP0004133_heterotaxia1.76913591
28MP0001697_abnormal_embryo_size1.74153661
29MP0002085_abnormal_embryonic_tissue1.72574890
30MP0001929_abnormal_gametogenesis1.71525202
31MP0001879_abnormal_lymphatic_vessel1.70290318
32MP0002084_abnormal_developmental_patter1.68870568
33MP0003984_embryonic_growth_retardation1.62631405
34MP0004233_abnormal_muscle_weight1.61694470
35MP0002080_prenatal_lethality1.59736430
36MP0002088_abnormal_embryonic_growth/wei1.58909565
37MP0003315_abnormal_perineum_morphology1.56815769
38MP0000015_abnormal_ear_pigmentation1.56812492
39MP0002086_abnormal_extraembryonic_tissu1.55624751
40MP0000653_abnormal_sex_gland1.53979014
41MP0003890_abnormal_embryonic-extraembry1.51984294
42MP0004197_abnormal_fetal_growth/weight/1.51616120
43MP0003121_genomic_imprinting1.47804013
44MP0004145_abnormal_muscle_electrophysio1.47780802
45MP0008995_early_reproductive_senescence1.44478219
46MP0005379_endocrine/exocrine_gland_phen1.44420646
47MP0003136_yellow_coat_color1.41423749
48MP0003567_abnormal_fetal_cardiomyocyte1.41234198
49MP0006292_abnormal_olfactory_placode1.36203673
50MP0001293_anophthalmia1.31151794
51MP0003878_abnormal_ear_physiology1.29163845
52MP0005377_hearing/vestibular/ear_phenot1.29163845
53MP0010030_abnormal_orbit_morphology1.28690344
54MP0003119_abnormal_digestive_system1.28133320
55MP0002160_abnormal_reproductive_system1.24010506
56MP0001177_atelectasis1.23649739
57MP0000313_abnormal_cell_death1.22659606
58MP0003698_abnormal_male_reproductive1.21245473
59MP0003183_abnormal_peptide_metabolism1.17005012
60MP0005389_reproductive_system_phenotype1.12902353
61MP0003959_abnormal_lean_body1.10879308
62MP0005395_other_phenotype1.06350154
63MP0005076_abnormal_cell_differentiation1.06049888
64MP0005409_darkened_coat_color1.05826570
65MP0003186_abnormal_redox_activity1.05481483
66MP0002019_abnormal_tumor_incidence1.02467352
67MP0008260_abnormal_autophagy1.01708428
68MP0004264_abnormal_extraembryonic_tissu1.00581221
69MP0009379_abnormal_foot_pigmentation0.97647326
70MP0001188_hyperpigmentation0.95403755
71MP0005266_abnormal_metabolism0.94980607
72MP0000358_abnormal_cell_content/0.94783545
73MP0009697_abnormal_copulation0.94139860
74MP0002161_abnormal_fertility/fecundity0.94044650
75MP0001119_abnormal_female_reproductive0.93726837
76MP0003943_abnormal_hepatobiliary_system0.92569131
77MP0005083_abnormal_biliary_tract0.92061202
78MP0000383_abnormal_hair_follicle0.91859888
79MP0005384_cellular_phenotype0.89558223
80MP0000516_abnormal_urinary_system0.89094308
81MP0005367_renal/urinary_system_phenotyp0.89094308
82MP0003936_abnormal_reproductive_system0.88942927
83MP0002163_abnormal_gland_morphology0.88650659
84MP0003566_abnormal_cell_adhesion0.88589589
85MP0006035_abnormal_mitochondrial_morpho0.87923183
86MP0002095_abnormal_skin_pigmentation0.87490307
87MP0003283_abnormal_digestive_organ0.87164208
88MP0000537_abnormal_urethra_morphology0.85819367
89MP0001919_abnormal_reproductive_system0.84311377
90MP0000490_abnormal_crypts_of0.84297104
91MP0005621_abnormal_cell_physiology0.83643755
92MP0000647_abnormal_sebaceous_gland0.82842919
93MP0000678_abnormal_parathyroid_gland0.81795547
94MP0004019_abnormal_vitamin_homeostasis0.80414165
95MP0001849_ear_inflammation0.80357927
96MP0003937_abnormal_limbs/digits/tail_de0.80166914
97MP0002111_abnormal_tail_morphology0.79399433
98MP0003699_abnormal_female_reproductive0.79296296
99MP0003221_abnormal_cardiomyocyte_apopto0.77693917
100MP0009672_abnormal_birth_weight0.77122343
101MP0005410_abnormal_fertilization0.76627325
102MP0009703_decreased_birth_body0.76240084
103MP0001764_abnormal_homeostasis0.74156613
104MP0001727_abnormal_embryo_implantation0.72317089
105MP0002269_muscular_atrophy0.71983980
106MP0004270_analgesia0.70671060
107MP0003646_muscle_fatigue0.69283874
108MP0010678_abnormal_skin_adnexa0.67050317
109MP0001286_abnormal_eye_development0.66837681
110MP0002132_abnormal_respiratory_system0.65816268
111MP0004215_abnormal_myocardial_fiber0.65285136
112MP0005023_abnormal_wound_healing0.64877202
113MP0004084_abnormal_cardiac_muscle0.64750353
114MP0003787_abnormal_imprinting0.64526111
115MP0001661_extended_life_span0.63694589
116MP0003861_abnormal_nervous_system0.62604281
117MP0003453_abnormal_keratinocyte_physiol0.61786624
118MP0003705_abnormal_hypodermis_morpholog0.61215153
119MP0000372_irregular_coat_pigmentation0.60499477
120MP0002396_abnormal_hematopoietic_system0.60114492
121MP0000631_abnormal_neuroendocrine_gland0.58317129
122MP0009053_abnormal_anal_canal0.57720013
123MP0005501_abnormal_skin_physiology0.57433459
124MP0002092_abnormal_eye_morphology0.56320260
125MP0000627_abnormal_mammary_gland0.56132422
126MP0004147_increased_porphyrin_level0.55813886
127MP0003935_abnormal_craniofacial_develop0.55813410
128MP0000750_abnormal_muscle_regeneration0.55627522
129MP0005084_abnormal_gallbladder_morpholo0.55563081
130MP0005075_abnormal_melanosome_morpholog0.55134787
131MP0000428_abnormal_craniofacial_morphol0.54969846
132MP0005058_abnormal_lysosome_morphology0.54496351
133MP0003950_abnormal_plasma_membrane0.54240325
134MP0004885_abnormal_endolymph0.53358962
135MP0005187_abnormal_penis_morphology0.53318625
136MP0008789_abnormal_olfactory_epithelium0.52844934
137MP0002233_abnormal_nose_morphology0.52481430
138MP0002127_abnormal_cardiovascular_syste0.51544771
139MP0001542_abnormal_bone_strength0.50568089
140MP0002796_impaired_skin_barrier0.50543798
141MP0006036_abnormal_mitochondrial_physio0.49235436
142MP0001915_intracranial_hemorrhage0.49207918

Predicted human phenotypes

RankGene SetZ-score
1Shoulder girdle muscle weakness (HP:0003547)6.81889451
2Birth length less than 3rd percentile (HP:0003561)5.56121663
3Rimmed vacuoles (HP:0003805)5.49588017
4Breast hypoplasia (HP:0003187)5.32608061
5Amyotrophic lateral sclerosis (HP:0007354)5.17490403
6Scotoma (HP:0000575)4.55833442
7Abnormality of the labia minora (HP:0012880)4.54050664
8Horizontal nystagmus (HP:0000666)4.51250473
9Ependymoma (HP:0002888)4.41789347
10Gonadotropin excess (HP:0000837)4.40884876
11Carpal bone hypoplasia (HP:0001498)4.39783774
12Upper motor neuron abnormality (HP:0002127)4.37633891
13Volvulus (HP:0002580)4.26012814
14Osteomalacia (HP:0002749)4.06590221
15Absent radius (HP:0003974)3.94037958
16Impulsivity (HP:0100710)3.81513011
17Chromosomal breakage induced by crosslinking agents (HP:0003221)3.75342071
18Chromsome breakage (HP:0040012)3.72910445
19Aplasia involving forearm bones (HP:0009822)3.70122460
20Absent forearm bone (HP:0003953)3.70122460
21Cerebral hypomyelination (HP:0006808)3.65930817
22Agnosia (HP:0010524)3.53155968
23Supernumerary spleens (HP:0009799)3.52273096
24Microvesicular hepatic steatosis (HP:0001414)3.48879421
25Medulloblastoma (HP:0002885)3.48732773
26Patellar aplasia (HP:0006443)3.48580886
27Degeneration of the lateral corticospinal tracts (HP:0002314)3.45020437
28Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.45020437
29Abnormality of the vocal cords (HP:0008777)3.35443935
30Aplasia/Hypoplasia involving the carpal bones (HP:0006502)3.33047262
31Abnormality of DNA repair (HP:0003254)3.30861600
32Aplasia/Hypoplasia of the patella (HP:0006498)3.29813051
33Selective tooth agenesis (HP:0001592)3.21614015
34Meckel diverticulum (HP:0002245)3.20045394
35Abnormality of the anterior horn cell (HP:0006802)3.19049612
36Degeneration of anterior horn cells (HP:0002398)3.19049612
37Rough bone trabeculation (HP:0100670)3.17658076
38Urethral obstruction (HP:0000796)3.16658769
39Colon cancer (HP:0003003)3.13505994
40Rhabdomyosarcoma (HP:0002859)3.05703853
41Abnormality of the ileum (HP:0001549)3.01445019
42Absent thumb (HP:0009777)2.99354235
43Oral leukoplakia (HP:0002745)2.96540124
44Astrocytoma (HP:0009592)2.92853482
45Abnormality of the astrocytes (HP:0100707)2.92853482
46Aplasia/hypoplasia of the humerus (HP:0006507)2.91984179
47Abnormality of chromosome stability (HP:0003220)2.91907165
48Central scotoma (HP:0000603)2.90379900
49Premature ovarian failure (HP:0008209)2.89726133
50Abnormality of the preputium (HP:0100587)2.86762610
51Glioma (HP:0009733)2.82400242
52Aplasia/Hypoplasia of the uvula (HP:0010293)2.82296199
53Papillary thyroid carcinoma (HP:0002895)2.81544666
54Lip pit (HP:0100267)2.78173132
55Neoplasm of the oral cavity (HP:0100649)2.66803008
56Poikiloderma (HP:0001029)2.66026593
57Shawl scrotum (HP:0000049)2.62226288
58Horseshoe kidney (HP:0000085)2.61467503
59Reticulocytopenia (HP:0001896)2.60403922
60Ureteral duplication (HP:0000073)2.56123435
61Abnormality of the corticospinal tract (HP:0002492)2.55983720
62Abnormal spermatogenesis (HP:0008669)2.54357692
63Stenosis of the external auditory canal (HP:0000402)2.53924988
64Duplicated collecting system (HP:0000081)2.52919627
65Small intestinal stenosis (HP:0012848)2.43639682
66Duodenal stenosis (HP:0100867)2.43639682
67Short humerus (HP:0005792)2.42920835
68Short tibia (HP:0005736)2.42495464
69Neoplasm of the pancreas (HP:0002894)2.42395494
70Secondary amenorrhea (HP:0000869)2.42274916
71Aplasia/Hypoplasia involving the musculature (HP:0001460)2.39058337
72Limb-girdle muscle weakness (HP:0003325)2.38446520
73Abnormality of the phalanges of the hallux (HP:0010057)2.38292386
74Spinal muscular atrophy (HP:0007269)2.37993322
75Premature skin wrinkling (HP:0100678)2.36824213
76Biliary tract neoplasm (HP:0100574)2.36527622
77Hyperglycinuria (HP:0003108)2.33254135
78Abnormal trabecular bone morphology (HP:0100671)2.30949423
79Delayed myelination (HP:0012448)2.28884597
80Bone marrow hypocellularity (HP:0005528)2.27879456
81Breast aplasia (HP:0100783)2.24279297
82CNS hypomyelination (HP:0003429)2.24170931
83Trismus (HP:0000211)2.22074318
84Duplication of thumb phalanx (HP:0009942)2.22061260
85Azoospermia (HP:0000027)2.21649670
86Neoplasm of striated muscle (HP:0009728)2.21168257
87Bowel incontinence (HP:0002607)2.18644670
88Rectal fistula (HP:0100590)2.18397657
89Rectovaginal fistula (HP:0000143)2.18397657
90Atrophy/Degeneration involving motor neurons (HP:0007373)2.16492636
91Abnormality of the salivary glands (HP:0010286)2.13865357
92Abnormality of the lower motor neuron (HP:0002366)2.13284149
93Abnormality of cochlea (HP:0000375)2.13234296
94Autoamputation (HP:0001218)2.13222269
95Aplasia/Hypoplasia of the tibia (HP:0005772)2.12397685
96Premature graying of hair (HP:0002216)2.10758319
97Aplasia/Hypoplasia of the breasts (HP:0010311)2.10714489
98Abnormal auditory evoked potentials (HP:0006958)2.09674225
99Abnormality of reticulocytes (HP:0004312)2.08871102
100Tracheoesophageal fistula (HP:0002575)2.08586878
101Ectopic kidney (HP:0000086)2.07572703
102Sloping forehead (HP:0000340)2.07147042
103Multiple enchondromatosis (HP:0005701)2.06243411
104Abnormality of the duodenum (HP:0002246)2.06176863
105Impaired vibration sensation in the lower limbs (HP:0002166)2.05866524
106Pallor (HP:0000980)2.05595673
107Tongue fasciculations (HP:0001308)2.05048444
108Fused cervical vertebrae (HP:0002949)2.04199178
109Megaloblastic anemia (HP:0001889)2.02845320
110Myelodysplasia (HP:0002863)2.02149426
111Abnormality of the renal collecting system (HP:0004742)2.01605882
112Aplasia/Hypoplasia of the sternum (HP:0006714)2.00780816
113Pelvic girdle muscle weakness (HP:0003749)2.00454917
114Abnormality of pyrimidine metabolism (HP:0004353)1.99670147
115Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.99305298
116Decreased subcutaneous fat (HP:0001002)1.99107201
117Abnormal large intestine physiology (HP:0012700)1.98987261
118Abnormality of abdominal situs (HP:0011620)1.98941225
119Abdominal situs inversus (HP:0003363)1.98941225
120Missing ribs (HP:0000921)1.98559914
121Triphalangeal thumb (HP:0001199)1.98386222
122Personality changes (HP:0000751)1.97990010
123Entropion (HP:0000621)1.97025588
124Abnormal biliary tract morphology (HP:0012440)1.96334716
125Basal cell carcinoma (HP:0002671)1.96087612
126Increased nuchal translucency (HP:0010880)1.95791791
127Abnormality of the shoulder girdle musculature (HP:0001435)1.95351607
128Abnormal protein glycosylation (HP:0012346)1.95117163
129Abnormal glycosylation (HP:0012345)1.95117163
130Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.95117163
131Abnormal protein N-linked glycosylation (HP:0012347)1.95117163
132Short thumb (HP:0009778)1.94947103
133Decreased activity of mitochondrial respiratory chain (HP:0008972)1.94355037
134Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.94355037
135Metaphyseal cupping (HP:0003021)1.93373747
136Esophageal atresia (HP:0002032)1.92352590
137Hoarse voice (HP:0001609)1.91941937
138Short middle phalanx of the 5th finger (HP:0004220)1.90456797
139Broad distal phalanx of finger (HP:0009836)1.89969263
140Facial cleft (HP:0002006)1.87537314
141Muscle fibrillation (HP:0010546)1.86398735
142Aplasia/Hypoplasia of the spleen (HP:0010451)1.86322840
143Atresia of the external auditory canal (HP:0000413)1.85604007
144Hypoplasia of the radius (HP:0002984)1.85528721
145Abnormality of glycine metabolism (HP:0010895)1.84745598
146Abnormality of serine family amino acid metabolism (HP:0010894)1.84745598
147Decreased lacrimation (HP:0000633)1.83973380
148Intellectual disability, profound (HP:0002187)1.83300276
149Hyperglycinemia (HP:0002154)1.82058793
150Cleft eyelid (HP:0000625)1.81639599
151Methylmalonic acidemia (HP:0002912)1.81488650
15211 pairs of ribs (HP:0000878)1.81355429
153Progressive external ophthalmoplegia (HP:0000590)1.80868064
154Breech presentation (HP:0001623)1.80650614
155Anal stenosis (HP:0002025)1.79639199
156Neoplasm of the colon (HP:0100273)1.79554882
157Retinal dysplasia (HP:0007973)1.79399189
158Abnormal lung lobation (HP:0002101)1.79022679
159Oligodactyly (HP:0012165)1.78780247
160Cutaneous melanoma (HP:0012056)1.77584291
161Progressive inability to walk (HP:0002505)1.74149736
162Tubulointerstitial nephritis (HP:0001970)1.72721547
163Blepharitis (HP:0000498)1.72483717
164Thyroid carcinoma (HP:0002890)1.70626330
165Reticulocytosis (HP:0001923)1.70605060
166Morphological abnormality of the inner ear (HP:0011390)1.69798020
167Upper limb muscle weakness (HP:0003484)1.69424403
168Capillary hemangiomas (HP:0005306)1.69177938
169Hydroureter (HP:0000072)1.66184875

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MUSK5.40206917
2WEE15.16427997
3BUB14.56709153
4EPHA23.37392731
5CDC73.28784106
6CDK193.21545521
7EIF2AK13.07029705
8NEK13.05931381
9TTK2.91478410
10PLK42.86808360
11TSSK62.81353496
12PNCK2.78855370
13KSR22.71691969
14TAF12.44253470
15SRPK12.42656784
16NEK22.39470183
17CDK122.29645972
18ACVR1B2.29527778
19AKT32.27442315
20PLK12.26628343
21EIF2AK32.01995841
22PRPF4B1.95358881
23STK161.88711597
24PLK31.88378152
25PDK31.79385670
26PDK41.79385670
27RAF11.78930944
28RPS6KB21.77688671
29BRSK21.57583774
30PDK21.52298967
31CHEK21.50121071
32CDK71.48233020
33MAP3K41.45841377
34KSR11.45682928
35ATR1.45302583
36STK38L1.38347647
37AURKB1.37320721
38TESK21.35988959
39AURKA1.34579372
40DYRK31.34474599
41NTRK31.33854935
42CHEK11.28166188
43ZAK1.26228637
44NEK91.25461572
45VRK11.24706043
46OXSR11.21202846
47MAP3K131.18219447
48MKNK21.16174785
49MAP3K81.16125920
50PTK2B1.15631318
51PASK1.15278691
52ALK1.14217794
53MAP3K21.10372286
54CDK81.07044383
55MKNK11.06153057
56YES11.00987972
57EPHA41.00903530
58PRKCI1.00571609
59CDK40.99647032
60BRAF0.97618232
61BRSK10.96722260
62BMPR1B0.94985566
63TIE10.94511869
64CLK10.94373407
65PIK3CG0.93540487
66LATS20.93516521
67NME20.93274691
68CDK20.92542768
69PBK0.91466110
70PAK40.90477820
71TLK10.89151900
72ATM0.89145435
73RPS6KB10.88063636
74BRD40.84401298
75STK40.81790465
76CDK90.78201927
77BMX0.77632258
78SCYL20.77455632
79CSF1R0.75030702
80MAPKAPK30.74441361
81CSNK2A20.74123629
82SGK10.69407029
83PAK10.68774795
84CDK10.67885409
85STK100.67876708
86CSNK1E0.67854570
87EIF2AK20.64602982
88CAMK1G0.62257387
89MELK0.62181040
90CCNB10.61683544
91CSNK2A10.61665738
92DMPK0.59486676
93CDK11A0.56921893
94DYRK20.56584699
95WNK10.55930409
96MST40.55633222
97IRAK40.55515938
98STK30.55011056
99PIM10.53166964
100MET0.51555596
101DYRK1A0.49411777
102CDK30.49368546
103MTOR0.48648547
104WNK40.48090776
105RPS6KA40.47529688
106NME10.47432399
107STK390.45563241
108BCKDK0.45377886
109MAP3K100.45119514
110PDGFRB0.44310198
111CDK140.44170700
112RPS6KL10.43664341
113RPS6KC10.43664341
114RPS6KA60.43246412
115TESK10.42935092
116CSNK1D0.42020487
117ARAF0.41474542
118MAP3K70.41473377
119WNK30.41291353
120PINK10.41083224
121RPS6KA10.40012880
122PRKDC0.38367116
123ICK0.38203172
124CDK150.32312419
125RPS6KA50.31610666
126MAP3K10.31272757
127RET0.31076497
128TAOK20.31059455
129MOS0.28754199
130CDK60.28296276
131GSK3B0.27458050
132IRAK30.26869553
133MAPK140.25020268
134CDK180.24981759
135AKT20.24960946
136BCR0.24590817
137TGFBR10.23882363
138MARK20.23789264
139PLK20.21771066
140MAPK100.18417927
141LATS10.18145969
142MAP3K90.17845477
143STK380.17700104
144TYRO30.17076372
145MAPK10.13584274
146NEK60.11938850
147AKT10.11799019
148MAP3K110.11614622
149STK240.11346374
150DAPK10.09669371

Predicted pathways (KEGG)

RankGene SetZ-score
1Dorso-ventral axis formation_Homo sapiens_hsa043206.45884589
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.59993420
3DNA replication_Homo sapiens_hsa030304.34718228
4Mismatch repair_Homo sapiens_hsa034304.30467068
5Proteasome_Homo sapiens_hsa030503.98843720
6RNA polymerase_Homo sapiens_hsa030203.64751016
7RNA transport_Homo sapiens_hsa030133.62573967
8Spliceosome_Homo sapiens_hsa030403.17098089
9Homologous recombination_Homo sapiens_hsa034402.96831454
10Nucleotide excision repair_Homo sapiens_hsa034202.91483059
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.79946131
12One carbon pool by folate_Homo sapiens_hsa006702.75426060
13Cell cycle_Homo sapiens_hsa041102.58338985
14Ribosome_Homo sapiens_hsa030102.58079246
15Base excision repair_Homo sapiens_hsa034102.52351987
16Fanconi anemia pathway_Homo sapiens_hsa034602.49759570
17Basal transcription factors_Homo sapiens_hsa030222.42280130
18Pyrimidine metabolism_Homo sapiens_hsa002402.36574747
19Non-homologous end-joining_Homo sapiens_hsa034502.01213149
20mRNA surveillance pathway_Homo sapiens_hsa030151.81986303
21RNA degradation_Homo sapiens_hsa030181.77185752
22Vitamin B6 metabolism_Homo sapiens_hsa007501.74807601
23Propanoate metabolism_Homo sapiens_hsa006401.66505329
24N-Glycan biosynthesis_Homo sapiens_hsa005101.59394948
25Glycosaminoglycan degradation_Homo sapiens_hsa005311.54788751
26p53 signaling pathway_Homo sapiens_hsa041151.50886973
27Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.42408301
28ABC transporters_Homo sapiens_hsa020101.40198412
29Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.39115099
30Purine metabolism_Homo sapiens_hsa002301.37257049
31Protein export_Homo sapiens_hsa030601.34095818
32Oocyte meiosis_Homo sapiens_hsa041141.29534829
33Epstein-Barr virus infection_Homo sapiens_hsa051691.21611770
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.20162444
35Fatty acid elongation_Homo sapiens_hsa000621.17591031
36Folate biosynthesis_Homo sapiens_hsa007901.17380358
37Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.16437423
38Biosynthesis of amino acids_Homo sapiens_hsa012301.15578563
392-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.10632856
40Cyanoamino acid metabolism_Homo sapiens_hsa004601.07453564
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.03343874
42Pentose phosphate pathway_Homo sapiens_hsa000301.00374011
43Fructose and mannose metabolism_Homo sapiens_hsa000510.96223593
44Selenocompound metabolism_Homo sapiens_hsa004500.95410810
45Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.94999636
46beta-Alanine metabolism_Homo sapiens_hsa004100.90402517
47Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.88364141
48SNARE interactions in vesicular transport_Homo sapiens_hsa041300.82404715
49Drug metabolism - other enzymes_Homo sapiens_hsa009830.81638847
50Regulation of autophagy_Homo sapiens_hsa041400.78852374
51Glutathione metabolism_Homo sapiens_hsa004800.77708343
52ErbB signaling pathway_Homo sapiens_hsa040120.77021922
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.76202416
54Carbon metabolism_Homo sapiens_hsa012000.74995022
55Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71913065
56Maturity onset diabetes of the young_Homo sapiens_hsa049500.68929715
57Systemic lupus erythematosus_Homo sapiens_hsa053220.68272764
58Viral carcinogenesis_Homo sapiens_hsa052030.66191552
59Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.65387895
60Huntingtons disease_Homo sapiens_hsa050160.64533900
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62901280
62Fatty acid metabolism_Homo sapiens_hsa012120.61284001
63Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59750572
64Fatty acid biosynthesis_Homo sapiens_hsa000610.57624072
65Acute myeloid leukemia_Homo sapiens_hsa052210.56381479
66Long-term depression_Homo sapiens_hsa047300.53422339
67Hippo signaling pathway_Homo sapiens_hsa043900.52838732
68Nicotine addiction_Homo sapiens_hsa050330.52214952
69Antigen processing and presentation_Homo sapiens_hsa046120.52092026
70Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50338357
71Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.49366827
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47422563
73Tyrosine metabolism_Homo sapiens_hsa003500.46004980
74Herpes simplex infection_Homo sapiens_hsa051680.44636825
75Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.43493344
76Chronic myeloid leukemia_Homo sapiens_hsa052200.43330754
77Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.42856207
78TGF-beta signaling pathway_Homo sapiens_hsa043500.40234976
79HTLV-I infection_Homo sapiens_hsa051660.39881031
80Steroid biosynthesis_Homo sapiens_hsa001000.39252120
81Linoleic acid metabolism_Homo sapiens_hsa005910.38980218
82Choline metabolism in cancer_Homo sapiens_hsa052310.38739180
83Arginine and proline metabolism_Homo sapiens_hsa003300.37562587
84Tight junction_Homo sapiens_hsa045300.35858719
85Glycerophospholipid metabolism_Homo sapiens_hsa005640.35555088
86MicroRNAs in cancer_Homo sapiens_hsa052060.34410526
87Thyroid cancer_Homo sapiens_hsa052160.34303995
88Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.33542869
89Metabolic pathways_Homo sapiens_hsa011000.32218449
90Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.31923308
91Arachidonic acid metabolism_Homo sapiens_hsa005900.30998986
92Type II diabetes mellitus_Homo sapiens_hsa049300.30634860
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.30520605
94Galactose metabolism_Homo sapiens_hsa000520.29694780
95Vitamin digestion and absorption_Homo sapiens_hsa049770.27416469
96Sulfur relay system_Homo sapiens_hsa041220.27151601
97Prolactin signaling pathway_Homo sapiens_hsa049170.27109151
98Olfactory transduction_Homo sapiens_hsa047400.26777994
99Collecting duct acid secretion_Homo sapiens_hsa049660.25955720
100Hedgehog signaling pathway_Homo sapiens_hsa043400.24401929
101mTOR signaling pathway_Homo sapiens_hsa041500.24326997
102Renal cell carcinoma_Homo sapiens_hsa052110.23059447
103alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.22740911
104Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.22193734
105Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.22141930
106Endometrial cancer_Homo sapiens_hsa052130.21340597
107Basal cell carcinoma_Homo sapiens_hsa052170.19913794
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.19831842
109Lysine degradation_Homo sapiens_hsa003100.19521782
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.17188018
111Adherens junction_Homo sapiens_hsa045200.16248056
112Small cell lung cancer_Homo sapiens_hsa052220.15500473
113Melanoma_Homo sapiens_hsa052180.14934768
114HIF-1 signaling pathway_Homo sapiens_hsa040660.14636651
115Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.14469532
116Renin-angiotensin system_Homo sapiens_hsa046140.14393821
117Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.13713584
118Parkinsons disease_Homo sapiens_hsa050120.11553718
119Alcoholism_Homo sapiens_hsa050340.11516859
120AMPK signaling pathway_Homo sapiens_hsa041520.10524934
121Insulin signaling pathway_Homo sapiens_hsa049100.09758411
122Retinol metabolism_Homo sapiens_hsa008300.09729236
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.09112556
124Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.08906937
125Notch signaling pathway_Homo sapiens_hsa043300.07833610
126Pyruvate metabolism_Homo sapiens_hsa006200.07431151
127Sphingolipid metabolism_Homo sapiens_hsa006000.06263427
128Legionellosis_Homo sapiens_hsa051340.06153721
129Pathways in cancer_Homo sapiens_hsa052000.05971663
130Colorectal cancer_Homo sapiens_hsa052100.05779110
131VEGF signaling pathway_Homo sapiens_hsa043700.02652788
132Fatty acid degradation_Homo sapiens_hsa000710.02347937
133Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.0556080
134Glycerolipid metabolism_Homo sapiens_hsa00561-0.0510183
135Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980-0.0474629
136FoxO signaling pathway_Homo sapiens_hsa04068-0.0372995
137Transcriptional misregulation in cancer_Homo sapiens_hsa05202-0.0361406
138Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603-0.0271522
139Prostate cancer_Homo sapiens_hsa05215-0.0225106
140Oxidative phosphorylation_Homo sapiens_hsa00190-0.0224456
141Thyroid hormone signaling pathway_Homo sapiens_hsa04919-0.0220463
142Apoptosis_Homo sapiens_hsa04210-0.0076985
143Wnt signaling pathway_Homo sapiens_hsa04310-0.0036738

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