MAGI2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.36597695
2positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.27033552
3regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.18567424
4vocalization behavior (GO:0071625)5.08416962
5neuron cell-cell adhesion (GO:0007158)5.07015514
6ionotropic glutamate receptor signaling pathway (GO:0035235)4.89760839
7synaptic vesicle exocytosis (GO:0016079)4.88142346
8locomotory exploration behavior (GO:0035641)4.80875062
9protein localization to synapse (GO:0035418)4.74419603
10regulation of glutamate receptor signaling pathway (GO:1900449)4.63899940
11glutamate receptor signaling pathway (GO:0007215)4.62309360
12glutamate secretion (GO:0014047)4.50571273
13positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.39667147
14synaptic transmission, glutamatergic (GO:0035249)4.38107298
15synaptic vesicle maturation (GO:0016188)4.34772470
16regulation of synaptic vesicle exocytosis (GO:2000300)4.34163658
17synaptic vesicle docking involved in exocytosis (GO:0016081)4.28636088
18presynaptic membrane assembly (GO:0097105)4.25972136
19neuronal action potential propagation (GO:0019227)4.25255797
20regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.14885982
21neurotransmitter-gated ion channel clustering (GO:0072578)4.14780428
22neuron-neuron synaptic transmission (GO:0007270)4.12032383
23behavioral response to nicotine (GO:0035095)4.08829970
24neuron recognition (GO:0008038)3.98426070
25presynaptic membrane organization (GO:0097090)3.97756445
26G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.93379212
27regulation of long-term neuronal synaptic plasticity (GO:0048169)3.92851705
28regulation of neuronal synaptic plasticity (GO:0048168)3.92222426
29membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.90588642
30regulation of excitatory postsynaptic membrane potential (GO:0060079)3.89129832
31regulation of synaptic vesicle transport (GO:1902803)3.88903791
32postsynaptic membrane organization (GO:0001941)3.83158909
33exploration behavior (GO:0035640)3.81907651
34pyrimidine nucleobase catabolic process (GO:0006208)3.81734167
35axonal fasciculation (GO:0007413)3.77638961
36neurotransmitter secretion (GO:0007269)3.73837352
37dendritic spine morphogenesis (GO:0060997)3.72016938
38long-term memory (GO:0007616)3.70931383
39gamma-aminobutyric acid signaling pathway (GO:0007214)3.70710316
40regulation of postsynaptic membrane potential (GO:0060078)3.69274655
41regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.62855188
42transmission of nerve impulse (GO:0019226)3.62242150
43regulation of dendritic spine morphogenesis (GO:0061001)3.60704206
44positive regulation of membrane potential (GO:0045838)3.58893879
45gamma-aminobutyric acid transport (GO:0015812)3.56009292
46neuronal action potential (GO:0019228)3.54159273
47cerebellar granule cell differentiation (GO:0021707)3.47760795
48negative regulation of synaptic transmission, GABAergic (GO:0032229)3.47023216
49positive regulation of synapse maturation (GO:0090129)3.46485392
50regulation of synaptic transmission, glutamatergic (GO:0051966)3.45142928
51negative regulation of cytosolic calcium ion concentration (GO:0051481)3.44344239
52positive regulation of dendritic spine morphogenesis (GO:0061003)3.41602692
53regulation of synaptic plasticity (GO:0048167)3.41383940
54cellular potassium ion homeostasis (GO:0030007)3.41090065
55regulation of synapse structural plasticity (GO:0051823)3.38306539
56long-term synaptic potentiation (GO:0060291)3.32667468
57layer formation in cerebral cortex (GO:0021819)3.31337126
58positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.29912177
59cerebellar Purkinje cell differentiation (GO:0021702)3.29900044
60nucleobase catabolic process (GO:0046113)3.29468509
61regulation of vesicle fusion (GO:0031338)3.27347258
62auditory behavior (GO:0031223)3.25043498
63central nervous system myelination (GO:0022010)3.24946880
64axon ensheathment in central nervous system (GO:0032291)3.24946880
65positive regulation of synapse assembly (GO:0051965)3.23858222
66startle response (GO:0001964)3.22766622
67membrane depolarization (GO:0051899)3.21494096
68positive regulation of dendritic spine development (GO:0060999)3.19755377
69positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.19751470
70response to histamine (GO:0034776)3.19228050
71neurotransmitter transport (GO:0006836)3.18582667
72negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.17292836
73serotonin metabolic process (GO:0042428)3.16120867
74central nervous system projection neuron axonogenesis (GO:0021952)3.13894200
75membrane depolarization during action potential (GO:0086010)3.13803281
76regulation of dendritic spine development (GO:0060998)3.13335345
77behavioral defense response (GO:0002209)3.12530433
78behavioral fear response (GO:0001662)3.12530433
79regulation of neurotransmitter secretion (GO:0046928)3.11857073
80regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.11178930
81dendrite morphogenesis (GO:0048813)3.10636344
82response to auditory stimulus (GO:0010996)3.08700988
83L-amino acid import (GO:0043092)3.08257065
84learning (GO:0007612)3.08252892
85adult walking behavior (GO:0007628)3.06338258
86synaptic vesicle endocytosis (GO:0048488)3.05641340
87membrane hyperpolarization (GO:0060081)3.03863256
88regulation of synapse maturation (GO:0090128)3.03254992
89synapse assembly (GO:0007416)3.01323159
90positive regulation of synaptic transmission, GABAergic (GO:0032230)2.99716101
91mechanosensory behavior (GO:0007638)2.96687983
92regulation of glutamate secretion (GO:0014048)2.96129835
93retinal cone cell development (GO:0046549)2.95106513
94fear response (GO:0042596)2.94613097
95C4-dicarboxylate transport (GO:0015740)2.92828656
96primary amino compound metabolic process (GO:1901160)2.91669995
97regulation of synapse assembly (GO:0051963)2.91656597
98regulation of neurotransmitter levels (GO:0001505)2.91079484
99neuromuscular process controlling balance (GO:0050885)2.90204829
100innervation (GO:0060384)2.90121671
101regulation of neurotransmitter transport (GO:0051588)2.89682691
102regulation of synaptic transmission (GO:0050804)2.88892864
103positive regulation of neurotransmitter secretion (GO:0001956)2.88871511
104dendritic spine organization (GO:0097061)2.87884814
105synaptic transmission (GO:0007268)2.84059093
106proline transport (GO:0015824)2.83651045
107prepulse inhibition (GO:0060134)2.82532310
108regulation of voltage-gated calcium channel activity (GO:1901385)2.82448042
109neuromuscular synaptic transmission (GO:0007274)2.81762747
110reflex (GO:0060004)2.81360102
111protein localization to cilium (GO:0061512)2.81298043
112nonmotile primary cilium assembly (GO:0035058)2.80468057
113neuronal ion channel clustering (GO:0045161)2.80325865
114detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.80073309
115positive regulation of synaptic transmission (GO:0050806)2.78448939
116urinary tract smooth muscle contraction (GO:0014848)2.77976890
117behavioral response to ethanol (GO:0048149)2.77341940
118righting reflex (GO:0060013)2.77200012
119positive regulation of neurotransmitter transport (GO:0051590)2.77131015
120action potential (GO:0001508)2.72777405
121regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.65453014
122regulation of action potential (GO:0098900)2.65349287
123regulation of respiratory system process (GO:0044065)2.64575627
124atrial cardiac muscle cell action potential (GO:0086014)2.63689616
125central nervous system neuron axonogenesis (GO:0021955)2.62831520
126adult behavior (GO:0030534)2.62526297
127regulation of neurotransmitter uptake (GO:0051580)2.58804584
128glycosphingolipid biosynthetic process (GO:0006688)2.58358772
129detection of calcium ion (GO:0005513)2.58101438
130protein polyglutamylation (GO:0018095)2.57327142
131detection of light stimulus involved in visual perception (GO:0050908)2.57079607
132detection of light stimulus involved in sensory perception (GO:0050962)2.57079607
133retinal ganglion cell axon guidance (GO:0031290)2.56752000
134epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.51998894
135regulation of synaptic transmission, GABAergic (GO:0032228)2.50729371
136synapse organization (GO:0050808)2.48016466
137regulation of calcium ion-dependent exocytosis (GO:0017158)2.45615414
138cellular potassium ion transport (GO:0071804)2.45138790
139potassium ion transmembrane transport (GO:0071805)2.45138790

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.82811241
2* GBX2_23144817_ChIP-Seq_PC3_Human3.92374334
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.02204247
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.97691934
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.97421356
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.59653469
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.59653469
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.55473931
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.49251923
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.48770227
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.46439337
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40620052
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.39166964
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.37014617
15* REST_21632747_ChIP-Seq_MESCs_Mouse2.35482099
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.32399762
17DROSHA_22980978_ChIP-Seq_HELA_Human2.27054917
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.17971242
19* RARB_27405468_Chip-Seq_BRAIN_Mouse2.13828378
20* RNF2_27304074_Chip-Seq_ESCs_Mouse2.11075138
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.10437423
22AR_21572438_ChIP-Seq_LNCaP_Human2.05056318
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.04981369
24TAF15_26573619_Chip-Seq_HEK293_Human1.95111932
25* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84797026
26REST_18959480_ChIP-ChIP_MESCs_Mouse1.84375565
27* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.83652747
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.83076633
29* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.81406909
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81021864
31* SMAD4_21799915_ChIP-Seq_A2780_Human1.73418877
32IKZF1_21737484_ChIP-ChIP_HCT116_Human1.71384670
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.69697391
34HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.65361594
35* GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.64200880
36* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.62018347
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.60982758
38EWS_26573619_Chip-Seq_HEK293_Human1.57614056
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.57143357
40P300_19829295_ChIP-Seq_ESCs_Human1.56032167
41PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.55434377
42MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.54702634
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.52864984
44* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.51492016
45IGF1R_20145208_ChIP-Seq_DFB_Human1.49774191
46* NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.49532929
47PIAS1_25552417_ChIP-Seq_VCAP_Human1.48281961
48SMAD3_21741376_ChIP-Seq_EPCs_Human1.48234348
49BMI1_23680149_ChIP-Seq_NPCS_Mouse1.47673840
50RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.47427211
51BCAT_22108803_ChIP-Seq_LS180_Human1.43508264
52SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43093932
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41376354
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40842867
55POU3F2_20337985_ChIP-ChIP_501MEL_Human1.38443356
56SALL1_21062744_ChIP-ChIP_HESCs_Human1.37305213
57PCGF2_27294783_Chip-Seq_ESCs_Mouse1.35243471
58CBP_20019798_ChIP-Seq_JUKART_Human1.33107020
59IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.33107020
60* STAT3_23295773_ChIP-Seq_U87_Human1.32024716
61* SOX2_21211035_ChIP-Seq_LN229_Gbm1.30199558
62AR_25329375_ChIP-Seq_VCAP_Human1.29736030
63ZNF274_21170338_ChIP-Seq_K562_Hela1.29676884
64SMAD_19615063_ChIP-ChIP_OVARY_Human1.27910580
65* RNF2_27304074_Chip-Seq_NSC_Mouse1.26441619
66TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25311502
67EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.24635237
68VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.22779238
69MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22712467
70NR3C1_23031785_ChIP-Seq_PC12_Mouse1.22604077
71RING1B_27294783_Chip-Seq_ESCs_Mouse1.22504206
72FUS_26573619_Chip-Seq_HEK293_Human1.21161868
73* TCF4_23295773_ChIP-Seq_U87_Human1.21096392
74CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.20759713
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19042046
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.18201818
77ERG_21242973_ChIP-ChIP_JURKAT_Human1.18115847
78* AR_19668381_ChIP-Seq_PC3_Human1.17111915
79TCF4_22108803_ChIP-Seq_LS180_Human1.16195690
80POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.14875649
81TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14875649
82BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.13916227
83SUZ12_27294783_Chip-Seq_NPCs_Mouse1.13826749
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.13428327
85KLF5_20875108_ChIP-Seq_MESCs_Mouse1.13371114
86CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13017149
87ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12660934
88TP53_16413492_ChIP-PET_HCT116_Human1.11966189
89* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.10873592
90P53_22387025_ChIP-Seq_ESCs_Mouse1.10428147
91KDM2B_26808549_Chip-Seq_REH_Human1.08867744
92NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08456689
93UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.07847285
94LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07182640
95TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07175287
96KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.06843919
97RING1B_27294783_Chip-Seq_NPCs_Mouse1.06505783
98SMAD4_21741376_ChIP-Seq_EPCs_Human1.06153685
99AHR_22903824_ChIP-Seq_MCF-7_Human1.05648520
100P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05245958
101FLI1_21867929_ChIP-Seq_TH2_Mouse1.04977470
102* ER_23166858_ChIP-Seq_MCF-7_Human1.04722980
103PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04710524
104RUNX2_22187159_ChIP-Seq_PCA_Human1.04553979
105TAL1_26923725_Chip-Seq_HPCs_Mouse1.03485433
106* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03088394
107NANOG_18555785_Chip-Seq_ESCs_Mouse1.02819716
108EZH2_27294783_Chip-Seq_NPCs_Mouse1.02019197
109FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.01845381
110TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00895889
111TP53_18474530_ChIP-ChIP_U2OS_Human1.00624194
112PRDM14_20953172_ChIP-Seq_ESCs_Human1.00219080
113RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00115664
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00069724
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98831778
116PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98668482
117TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97947249
118VDR_22108803_ChIP-Seq_LS180_Human0.97855534
119SMAD3_21741376_ChIP-Seq_HESCs_Human0.95463792
120SMAD4_21741376_ChIP-Seq_HESCs_Human0.94009789
121SMAD3_21741376_ChIP-Seq_ESCs_Human0.89818955
122JUN_21703547_ChIP-Seq_K562_Human0.89768512
123E2F1_18555785_Chip-Seq_ESCs_Mouse0.89688414
124EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.88003509

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.07984194
2MP0003880_abnormal_central_pattern5.40079496
3MP0003635_abnormal_synaptic_transmissio3.94846437
4MP0004270_analgesia3.43462022
5MP0009745_abnormal_behavioral_response3.34778984
6MP0002063_abnormal_learning/memory/cond3.22002165
7MP0002064_seizures3.11296865
8MP0009046_muscle_twitch2.97152085
9MP0001968_abnormal_touch/_nociception2.80761556
10MP0002572_abnormal_emotion/affect_behav2.78031834
11MP0001486_abnormal_startle_reflex2.67496899
12MP0005423_abnormal_somatic_nervous2.63634089
13MP0002272_abnormal_nervous_system2.63616133
14MP0002734_abnormal_mechanical_nocicepti2.40030468
15MP0002735_abnormal_chemical_nociception2.28207842
16MP0002822_catalepsy2.21225160
17MP0002736_abnormal_nociception_after2.20848767
18MP0001440_abnormal_grooming_behavior2.17446544
19MP0000778_abnormal_nervous_system2.14293925
20MP0001501_abnormal_sleep_pattern2.09949497
21MP0002067_abnormal_sensory_capabilities2.00623633
22MP0005646_abnormal_pituitary_gland1.91757526
23MP0008877_abnormal_DNA_methylation1.85810405
24MP0001984_abnormal_olfaction1.82772279
25MP0001970_abnormal_pain_threshold1.81043177
26MP0002733_abnormal_thermal_nociception1.77476707
27MP0008569_lethality_at_weaning1.74250403
28MP0002557_abnormal_social/conspecific_i1.74100868
29MP0002184_abnormal_innervation1.74093872
30MP0002102_abnormal_ear_morphology1.62454206
31MP0009780_abnormal_chondrocyte_physiolo1.59661501
32MP0005386_behavior/neurological_phenoty1.58828005
33MP0004924_abnormal_behavior1.58828005
34MP0005645_abnormal_hypothalamus_physiol1.55428292
35MP0006276_abnormal_autonomic_nervous1.54594908
36MP0004811_abnormal_neuron_physiology1.53637902
37MP0000955_abnormal_spinal_cord1.53352738
38MP0001529_abnormal_vocalization1.52000707
39MP0003329_amyloid_beta_deposits1.51313259
40MP0004885_abnormal_endolymph1.49790691
41MP0001502_abnormal_circadian_rhythm1.47976516
42* MP0002882_abnormal_neuron_morphology1.47748754
43MP0001188_hyperpigmentation1.44912280
44MP0001905_abnormal_dopamine_level1.42710882
45MP0002066_abnormal_motor_capabilities/c1.40773489
46MP0005551_abnormal_eye_electrophysiolog1.36607061
47MP0002909_abnormal_adrenal_gland1.33724950
48MP0003879_abnormal_hair_cell1.33004301
49MP0003787_abnormal_imprinting1.32852796
50MP0004142_abnormal_muscle_tone1.32072337
51MP0003195_calcinosis1.30304406
52MP0003633_abnormal_nervous_system1.28849185
53MP0003121_genomic_imprinting1.27548362
54MP0004858_abnormal_nervous_system1.25761459
55MP0003122_maternal_imprinting1.24576450
56MP0004742_abnormal_vestibular_system1.23866457
57MP0000566_synostosis1.22234028
58MP0000920_abnormal_myelination1.19222131
59MP0002152_abnormal_brain_morphology1.17211089
60MP0003631_nervous_system_phenotype1.15647631
61MP0004145_abnormal_muscle_electrophysio1.14496942
62MP0004133_heterotaxia1.14409943
63MP0001986_abnormal_taste_sensitivity1.12139680
64MP0005171_absent_coat_pigmentation1.10503558
65MP0002229_neurodegeneration1.10446263
66MP0003690_abnormal_glial_cell1.09967053
67MP0003283_abnormal_digestive_organ1.09012511
68MP0002653_abnormal_ependyma_morphology1.08952092
69MP0005409_darkened_coat_color1.05466423
70MP0004147_increased_porphyrin_level1.04602802
71MP0001963_abnormal_hearing_physiology1.01813947
72MP0002938_white_spotting1.01059166
73MP0002751_abnormal_autonomic_nervous0.99040957
74MP0003634_abnormal_glial_cell0.98687639
75MP0001485_abnormal_pinna_reflex0.96651015
76MP0002752_abnormal_somatic_nervous0.96133806
77MP0003632_abnormal_nervous_system0.94390760
78MP0000631_abnormal_neuroendocrine_gland0.92973697
79MP0000751_myopathy0.91952308
80MP0002876_abnormal_thyroid_physiology0.90035963
81MP0005187_abnormal_penis_morphology0.88893022
82MP0002234_abnormal_pharynx_morphology0.88638391
83MP0002069_abnormal_eating/drinking_beha0.87569454
84MP0004085_abnormal_heartbeat0.87379948
85MP0004043_abnormal_pH_regulation0.87192110
86MP0000427_abnormal_hair_cycle0.86909438
87MP0003137_abnormal_impulse_conducting0.85735403
88MP0003890_abnormal_embryonic-extraembry0.85368188
89MP0003119_abnormal_digestive_system0.82716477
90MP0001299_abnormal_eye_distance/0.82629600
91MP0001177_atelectasis0.82610570
92MP0008872_abnormal_physiological_respon0.82137594
93MP0005174_abnormal_tail_pigmentation0.77609999
94MP0004215_abnormal_myocardial_fiber0.77251151
95MP0006072_abnormal_retinal_apoptosis0.76884824
96MP0002090_abnormal_vision0.76737569
97MP0006292_abnormal_olfactory_placode0.75352143
98MP0010386_abnormal_urinary_bladder0.74482954
99MP0005499_abnormal_olfactory_system0.71965363
100MP0005394_taste/olfaction_phenotype0.71965363
101MP0000026_abnormal_inner_ear0.71717243
102MP0000569_abnormal_digit_pigmentation0.70983908
103MP0002837_dystrophic_cardiac_calcinosis0.70751544
104MP0008874_decreased_physiological_sensi0.70693907
105MP0005253_abnormal_eye_physiology0.68424567
106MP0005084_abnormal_gallbladder_morpholo0.67503153
107MP0003861_abnormal_nervous_system0.67070269
108MP0002928_abnormal_bile_duct0.66434762
109MP0003136_yellow_coat_color0.66009295
110MP0005623_abnormal_meninges_morphology0.63528332
111MP0001664_abnormal_digestion0.62849513
112MP0001943_abnormal_respiration0.60601345
113MP0002638_abnormal_pupillary_reflex0.60162898
114MP0003938_abnormal_ear_development0.59918985
115MP0004484_altered_response_of0.59283649
116MP0010769_abnormal_survival0.56332405
117MP0010770_preweaning_lethality0.56130061
118MP0002082_postnatal_lethality0.56130061
119MP0005535_abnormal_body_temperature0.55760013
120MP0005195_abnormal_posterior_eye0.53616403

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.94695700
2Myokymia (HP:0002411)6.07107276
3Focal seizures (HP:0007359)5.45107036
4Epileptic encephalopathy (HP:0200134)4.95561913
5Atonic seizures (HP:0010819)4.36608514
6Febrile seizures (HP:0002373)4.23690530
7Hyperventilation (HP:0002883)4.05113960
8Progressive cerebellar ataxia (HP:0002073)4.00074094
9Broad-based gait (HP:0002136)3.97087551
10Visual hallucinations (HP:0002367)3.83142028
11Absence seizures (HP:0002121)3.71253044
12Dialeptic seizures (HP:0011146)3.68631104
13Gaze-evoked nystagmus (HP:0000640)3.45203542
14Generalized tonic-clonic seizures (HP:0002069)3.43500311
15Dysdiadochokinesis (HP:0002075)3.38896157
16Pancreatic cysts (HP:0001737)3.37232959
17Pancreatic fibrosis (HP:0100732)3.35401465
18Dysmetria (HP:0001310)3.24698190
19True hermaphroditism (HP:0010459)3.15567242
20Supranuclear gaze palsy (HP:0000605)3.13503448
21Action tremor (HP:0002345)3.08571240
22Abnormality of midbrain morphology (HP:0002418)3.06089747
23Molar tooth sign on MRI (HP:0002419)3.06089747
24Nephronophthisis (HP:0000090)3.05597329
25Truncal ataxia (HP:0002078)2.94370343
26Congenital stationary night blindness (HP:0007642)2.88698291
27Impaired vibration sensation in the lower limbs (HP:0002166)2.86361677
28Abnormal eating behavior (HP:0100738)2.82405547
29Ankle clonus (HP:0011448)2.80598262
30Neurofibrillary tangles (HP:0002185)2.80192396
31Excessive salivation (HP:0003781)2.79975534
32Drooling (HP:0002307)2.79975534
33Poor eye contact (HP:0000817)2.77039574
34Amblyopia (HP:0000646)2.69067155
35Gait imbalance (HP:0002141)2.64805113
36Abnormality of the renal medulla (HP:0100957)2.62884400
37Scanning speech (HP:0002168)2.62370148
38Spastic gait (HP:0002064)2.61808371
39Postural instability (HP:0002172)2.61316560
40Genetic anticipation (HP:0003743)2.60188862
41Depression (HP:0000716)2.58506282
42Urinary bladder sphincter dysfunction (HP:0002839)2.57666353
43Absent speech (HP:0001344)2.55908256
44Hemiparesis (HP:0001269)2.55591722
45Cerebral inclusion bodies (HP:0100314)2.51946900
46Epileptiform EEG discharges (HP:0011182)2.49936150
47Abnormality of the corticospinal tract (HP:0002492)2.47702777
48Anxiety (HP:0000739)2.47030764
49Type II lissencephaly (HP:0007260)2.46026049
50Abnormal social behavior (HP:0012433)2.43890275
51Impaired social interactions (HP:0000735)2.43890275
52Diplopia (HP:0000651)2.40996433
53Abnormality of binocular vision (HP:0011514)2.40996433
54Chronic hepatic failure (HP:0100626)2.40935322
55Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.37334351
56Degeneration of the lateral corticospinal tracts (HP:0002314)2.37334351
57Insidious onset (HP:0003587)2.34710631
58Termporal pattern (HP:0011008)2.34710631
59Cystic liver disease (HP:0006706)2.32424163
60Progressive inability to walk (HP:0002505)2.29976040
61Limb dystonia (HP:0002451)2.29912555
62Lissencephaly (HP:0001339)2.28111938
63Protruding tongue (HP:0010808)2.27681899
64Intention tremor (HP:0002080)2.26766717
65Polyphagia (HP:0002591)2.25667743
66Exotropia (HP:0000577)2.25655917
67Hypothermia (HP:0002045)2.25246815
68Blue irides (HP:0000635)2.25197951
69Congenital primary aphakia (HP:0007707)2.24202439
70EEG with generalized epileptiform discharges (HP:0011198)2.23978116
71Megalencephaly (HP:0001355)2.23608422
72Optic nerve hypoplasia (HP:0000609)2.23516176
73Medial flaring of the eyebrow (HP:0010747)2.22711114
74Abnormality of the labia minora (HP:0012880)2.22238036
75Abnormality of the renal cortex (HP:0011035)2.20377314
76Absent/shortened dynein arms (HP:0200106)2.20197850
77Dynein arm defect of respiratory motile cilia (HP:0012255)2.20197850
78Intestinal atresia (HP:0011100)2.19944086
79Urinary urgency (HP:0000012)2.19857497
80Stereotypic behavior (HP:0000733)2.13483555
81Impaired smooth pursuit (HP:0007772)2.12208936
82Polydipsia (HP:0001959)2.10811092
83Abnormal drinking behavior (HP:0030082)2.10811092
84Genital tract atresia (HP:0001827)2.09758283
85Specific learning disability (HP:0001328)2.09061313
86Inability to walk (HP:0002540)2.07976502
87Hemiplegia (HP:0002301)2.07843092
88Vaginal atresia (HP:0000148)2.07374108
89Nephrogenic diabetes insipidus (HP:0009806)2.06072253
90Clumsiness (HP:0002312)2.04495503
91Attenuation of retinal blood vessels (HP:0007843)2.04096988
92Abnormal ciliary motility (HP:0012262)2.03362516
93Hypsarrhythmia (HP:0002521)2.02954263
94Aplasia/Hypoplasia of the tibia (HP:0005772)2.02607381
95Lower limb muscle weakness (HP:0007340)2.02558008
96Abolished electroretinogram (ERG) (HP:0000550)2.01651453
97Torticollis (HP:0000473)2.00850063
98Aplasia involving bones of the upper limbs (HP:0009823)1.99902931
99Aplasia of the phalanges of the hand (HP:0009802)1.99902931
100Aplasia involving bones of the extremities (HP:0009825)1.99902931
101Thickened helices (HP:0000391)1.99696474
102Mutism (HP:0002300)1.99136209
103Pheochromocytoma (HP:0002666)1.99070376
104Bradykinesia (HP:0002067)1.98145203
105Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.97891652
106Bony spicule pigmentary retinopathy (HP:0007737)1.93733512
107Abnormal respiratory motile cilium physiology (HP:0012261)1.93510847
108Widely spaced teeth (HP:0000687)1.92805519
109Large for gestational age (HP:0001520)1.92486986
110Poor coordination (HP:0002370)1.92287071
111Sclerocornea (HP:0000647)1.91200618
112Increased circulating renin level (HP:0000848)1.90720522
113Impaired vibratory sensation (HP:0002495)1.90602966
114Abnormality of salivation (HP:0100755)1.89975522
115Keratoconus (HP:0000563)1.89543388
116Increased corneal curvature (HP:0100692)1.89543388
117Pachygyria (HP:0001302)1.88591224
118Focal dystonia (HP:0004373)1.88578864
119Gait ataxia (HP:0002066)1.88452152
120Fetal akinesia sequence (HP:0001989)1.87234680
121Generalized myoclonic seizures (HP:0002123)1.87034193
122Postaxial hand polydactyly (HP:0001162)1.86610593
123Abnormality of the lower motor neuron (HP:0002366)1.86142757
124Dysmetric saccades (HP:0000641)1.82969359
125Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.82072411
126Decreased central vision (HP:0007663)1.80884566
127Status epilepticus (HP:0002133)1.80744531
128Spastic tetraplegia (HP:0002510)1.80593507
129Abnormality of ocular smooth pursuit (HP:0000617)1.79815746
130Incomplete penetrance (HP:0003829)1.79665777
131Sleep apnea (HP:0010535)1.77699645
132Abnormal rod and cone electroretinograms (HP:0008323)1.77633163
133Aplasia/Hypoplasia of the tongue (HP:0010295)1.77435783
134Fair hair (HP:0002286)1.77160734
135Agitation (HP:0000713)1.76856432
136Peripheral hypomyelination (HP:0007182)1.76093572
137Prolonged QT interval (HP:0001657)1.74849348
138Retinal dysplasia (HP:0007973)1.74277822
139Methylmalonic aciduria (HP:0012120)1.73575488
140Abnormal respiratory epithelium morphology (HP:0012253)1.72829846
141Abnormal respiratory motile cilium morphology (HP:0005938)1.72829846
142Decreased circulating renin level (HP:0003351)1.72181196
143Congenital hepatic fibrosis (HP:0002612)1.71883774
144Anencephaly (HP:0002323)1.69589059
145Polyuria (HP:0000103)1.69219965
146Short foot (HP:0001773)1.69043946
147Cerebellar dysplasia (HP:0007033)1.68149715
148Tubular atrophy (HP:0000092)1.67731890
149Oligodactyly (hands) (HP:0001180)1.65480567

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.90020274
2EPHA44.76587784
3NTRK34.39273309
4CASK3.52054673
5MARK13.11303944
6MAP3K42.72006066
7MAP2K72.47592151
8MAP3K92.45722809
9PRPF4B2.38736856
10TNIK2.30230467
11NTRK22.23613625
12PAK62.11324013
13BMPR1B2.06326213
14DAPK21.97530028
15MINK11.90171492
16OXSR11.76981836
17ADRBK21.74635673
18CDK191.73517512
19MAPK131.66900719
20PNCK1.59513678
21CAMKK21.58514782
22KSR11.53547910
23GRK11.50687498
24CDK51.49568767
25MAP4K21.49354165
26MAP2K41.46685957
27PLK21.44482052
28CAMK2B1.39237871
29ACVR1B1.37716615
30CAMKK11.37303776
31RIPK41.35858771
32NTRK11.34890421
33DYRK21.33842342
34DAPK11.27471889
35STK391.26573348
36CAMK2A1.26111375
37PRKCG1.23093680
38MAP3K121.22975183
39SGK4941.15314922
40SGK2231.15314922
41KSR21.15150516
42UHMK11.15094290
43MKNK21.13441136
44PRKD31.13037100
45PHKG21.10298060
46PHKG11.10298060
47FES1.07471800
48NUAK11.05990562
49GRK51.04074139
50CSNK1G11.01507280
51TYRO30.98069720
52SIK20.96577654
53ZAK0.96141372
54CSNK1G30.94572062
55PTK2B0.93364337
56MARK20.93157854
57CDK180.93055410
58CDK150.91081811
59PAK30.89566290
60SGK20.89295053
61CSNK1A1L0.89147674
62CAMK10.87707142
63CDK140.84073016
64CSNK1G20.84060360
65STK110.82872778
66STK38L0.79508942
67DYRK1A0.79420899
68AKT30.79184182
69STK380.79164601
70FGR0.78491726
71CDK11A0.77780023
72BMPR20.75772370
73BRD40.75479413
74PKN10.75466462
75CAMK2D0.73253728
76ERBB30.73194291
77SGK10.72524283
78PRKCE0.71133456
79ADRBK10.70478709
80WNK30.67481686
81BCR0.66568940
82CAMK2G0.66282199
83FGFR20.65882213
84MAP3K20.65765300
85CDK30.64303392
86MAP3K130.62696360
87EPHA30.61765227
88WNK40.61712582
89NEK60.61165861
90WNK10.59842460
91SGK30.59779798
92NME10.59444420
93CDC42BPA0.59307027
94PINK10.57655637
95ARAF0.56701205
96CAMK1G0.56539434
97TRIM280.56441430
98PDPK10.54811808
99PRKCH0.53939882
100PRKD20.52513471
101MUSK0.51245058
102CAMK1D0.51083432
103INSRR0.49840122
104ROCK20.48531238
105CSNK1D0.47905399
106RPS6KA30.47487768
107CSNK1A10.47314989
108PRKG10.46051981
109PRKCZ0.45515863
110TAOK10.44542465
111CAMK40.44452886
112FYN0.43112815
113TAOK20.43078353
114RET0.42499542
115MAPKAPK50.41300669
116PDK10.40965513
117MAPK100.40571524
118TAOK30.39504759
119LATS20.38627073
120RAF10.38142246
121CCNB10.37289037
122PRKACA0.37000594
123OBSCN0.36630455
124PRKACB0.36607869
125TIE10.35601014
126PRKCA0.35103331
127PRKAA10.33051660
128PRKCB0.32899266
129MKNK10.32459512
130ERBB20.31895357
131CSNK1E0.30650605
132TAF10.30503236
133VRK10.30118379
134TGFBR10.29124847

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.13588927
2Synaptic vesicle cycle_Homo sapiens_hsa047212.90517525
3Glutamatergic synapse_Homo sapiens_hsa047242.89998355
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.86334692
5Circadian entrainment_Homo sapiens_hsa047132.79347882
6GABAergic synapse_Homo sapiens_hsa047272.76261205
7Olfactory transduction_Homo sapiens_hsa047402.74448032
8Morphine addiction_Homo sapiens_hsa050322.70943906
9Long-term potentiation_Homo sapiens_hsa047202.69517226
10Amphetamine addiction_Homo sapiens_hsa050312.58667758
11Salivary secretion_Homo sapiens_hsa049702.15435357
12Dopaminergic synapse_Homo sapiens_hsa047282.13866645
13Insulin secretion_Homo sapiens_hsa049111.96125332
14Taste transduction_Homo sapiens_hsa047421.95240543
15Butanoate metabolism_Homo sapiens_hsa006501.92295375
16Serotonergic synapse_Homo sapiens_hsa047261.85025208
17Renin secretion_Homo sapiens_hsa049241.82635317
18Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.82552978
19Cholinergic synapse_Homo sapiens_hsa047251.82193878
20Gastric acid secretion_Homo sapiens_hsa049711.79926274
21Long-term depression_Homo sapiens_hsa047301.77808575
22Cocaine addiction_Homo sapiens_hsa050301.73157274
23Calcium signaling pathway_Homo sapiens_hsa040201.70883513
24Maturity onset diabetes of the young_Homo sapiens_hsa049501.70678010
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.69245777
26Oxytocin signaling pathway_Homo sapiens_hsa049211.64355503
27Axon guidance_Homo sapiens_hsa043601.56396473
28Collecting duct acid secretion_Homo sapiens_hsa049661.52453443
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.47663210
30Linoleic acid metabolism_Homo sapiens_hsa005911.41624601
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.36263247
32Propanoate metabolism_Homo sapiens_hsa006401.34359107
33cAMP signaling pathway_Homo sapiens_hsa040241.33304356
34GnRH signaling pathway_Homo sapiens_hsa049121.32650517
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.30820738
36Gap junction_Homo sapiens_hsa045401.27285640
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.22812904
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.22059845
39Phototransduction_Homo sapiens_hsa047441.20407980
40Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.19116669
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.13988666
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12208234
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.11034681
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06502003
45Protein export_Homo sapiens_hsa030601.04028778
46Tryptophan metabolism_Homo sapiens_hsa003801.03930605
47Type II diabetes mellitus_Homo sapiens_hsa049301.03635316
48ErbB signaling pathway_Homo sapiens_hsa040121.02873715
49Vascular smooth muscle contraction_Homo sapiens_hsa042701.02670356
50Melanogenesis_Homo sapiens_hsa049160.99479694
51Cardiac muscle contraction_Homo sapiens_hsa042600.97976591
52ABC transporters_Homo sapiens_hsa020100.96890010
53Vibrio cholerae infection_Homo sapiens_hsa051100.95500457
54beta-Alanine metabolism_Homo sapiens_hsa004100.94875725
55Estrogen signaling pathway_Homo sapiens_hsa049150.94865685
56Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.91839235
57Pancreatic secretion_Homo sapiens_hsa049720.91034798
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.89972960
59Parkinsons disease_Homo sapiens_hsa050120.88874800
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.87614141
61Glioma_Homo sapiens_hsa052140.86305112
62Phospholipase D signaling pathway_Homo sapiens_hsa040720.84603004
63Dilated cardiomyopathy_Homo sapiens_hsa054140.83091301
64Histidine metabolism_Homo sapiens_hsa003400.82151398
65Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80393942
66Regulation of autophagy_Homo sapiens_hsa041400.76926154
67Choline metabolism in cancer_Homo sapiens_hsa052310.76840426
68Selenocompound metabolism_Homo sapiens_hsa004500.76515366
69Basal transcription factors_Homo sapiens_hsa030220.75628017
70Circadian rhythm_Homo sapiens_hsa047100.74565934
71MAPK signaling pathway_Homo sapiens_hsa040100.74563618
72Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73356692
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72537055
74Ras signaling pathway_Homo sapiens_hsa040140.71286719
75Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70705694
76Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.70675968
77Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.70094442
78Dorso-ventral axis formation_Homo sapiens_hsa043200.68165412
79Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.64620364
80Primary bile acid biosynthesis_Homo sapiens_hsa001200.64520712
81Thyroid hormone synthesis_Homo sapiens_hsa049180.64104359
82Huntingtons disease_Homo sapiens_hsa050160.63932074
83Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63365573
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.61860391
85Wnt signaling pathway_Homo sapiens_hsa043100.60769665
86Oocyte meiosis_Homo sapiens_hsa041140.60329257
87Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.58676847
88Alzheimers disease_Homo sapiens_hsa050100.54946631
89Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.54625279
90VEGF signaling pathway_Homo sapiens_hsa043700.53268547
91Peroxisome_Homo sapiens_hsa041460.52315203
92* Rap1 signaling pathway_Homo sapiens_hsa040150.52262982
93Ovarian steroidogenesis_Homo sapiens_hsa049130.50974222
94Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.50801101
95Inositol phosphate metabolism_Homo sapiens_hsa005620.49501231
96Caffeine metabolism_Homo sapiens_hsa002320.49373246
97Chemical carcinogenesis_Homo sapiens_hsa052040.49079628
98Fatty acid biosynthesis_Homo sapiens_hsa000610.48541140
99Glycerolipid metabolism_Homo sapiens_hsa005610.48353145
100Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.48004799
101Nitrogen metabolism_Homo sapiens_hsa009100.47570934
102Glucagon signaling pathway_Homo sapiens_hsa049220.47391688
103Alcoholism_Homo sapiens_hsa050340.47169248
104Sphingolipid signaling pathway_Homo sapiens_hsa040710.46660544
105Mineral absorption_Homo sapiens_hsa049780.46294037
106Renal cell carcinoma_Homo sapiens_hsa052110.43235258
107Retinol metabolism_Homo sapiens_hsa008300.42146007
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41743113
109Hippo signaling pathway_Homo sapiens_hsa043900.41567125
110Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.40906922
111Carbohydrate digestion and absorption_Homo sapiens_hsa049730.40123227
112Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.39067084
113Endocytosis_Homo sapiens_hsa041440.38339249
114Ether lipid metabolism_Homo sapiens_hsa005650.38122393
115Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.38085440
116Thyroid hormone signaling pathway_Homo sapiens_hsa049190.37119050
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.36885846
118Fanconi anemia pathway_Homo sapiens_hsa034600.36022404
119Oxidative phosphorylation_Homo sapiens_hsa001900.34832653
120Basal cell carcinoma_Homo sapiens_hsa052170.34765440
121African trypanosomiasis_Homo sapiens_hsa051430.32967245
122Neurotrophin signaling pathway_Homo sapiens_hsa047220.32837207
123SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32511084
124Bile secretion_Homo sapiens_hsa049760.31767017
125Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.31477450
126Hedgehog signaling pathway_Homo sapiens_hsa043400.30531852
127Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30352341
128Longevity regulating pathway - mammal_Homo sapiens_hsa042110.28517817
129Prion diseases_Homo sapiens_hsa050200.28210049
130Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26592242
131Type I diabetes mellitus_Homo sapiens_hsa049400.26570583
132Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.25454334
133Chemokine signaling pathway_Homo sapiens_hsa040620.25366350
134Regulation of actin cytoskeleton_Homo sapiens_hsa048100.24878187

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