MALRD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epoxygenase P450 pathway (GO:0019373)7.35319428
2regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)7.22812865
3regulation of guanylate cyclase activity (GO:0031282)7.17726449
4NADH metabolic process (GO:0006734)6.80518924
5actin filament depolymerization (GO:0030042)6.59555119
6fat-soluble vitamin biosynthetic process (GO:0042362)6.55748956
7adhesion of symbiont to host cell (GO:0044650)5.96507196
8virion attachment to host cell (GO:0019062)5.96507196
9positive regulation of guanylate cyclase activity (GO:0031284)5.92099096
10vitamin A metabolic process (GO:0006776)5.88219637
11UDP-N-acetylglucosamine metabolic process (GO:0006047)5.73540500
12digestive system process (GO:0022600)5.67092598
13drug catabolic process (GO:0042737)5.63257708
14cellular glucuronidation (GO:0052695)5.48245445
15uronic acid metabolic process (GO:0006063)5.37208246
16glucuronate metabolic process (GO:0019585)5.37208246
17bile acid and bile salt transport (GO:0015721)5.12206941
18modified amino acid transport (GO:0072337)5.02900998
19regulation of cellular extravasation (GO:0002691)5.00046332
20glucose 6-phosphate metabolic process (GO:0051156)4.98714300
21cellular response to hepatocyte growth factor stimulus (GO:0035729)4.98637789
22response to hepatocyte growth factor (GO:0035728)4.98637789
23flavonoid metabolic process (GO:0009812)4.92927021
24bundle of His cell to Purkinje myocyte communication (GO:0086069)4.91852940
25purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.84546404
263-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.84546404
27adhesion of symbiont to host (GO:0044406)4.81873758
28lipoprotein transport (GO:0042953)4.59984864
29lipoprotein metabolic process (GO:0042157)4.59363915
30regulation of cGMP biosynthetic process (GO:0030826)4.50005884
31sulfate transmembrane transport (GO:1902358)4.46965798
32glycolipid catabolic process (GO:0019377)4.37440234
33digestion (GO:0007586)4.36387836
34peptide hormone processing (GO:0016486)4.35805751
35plasma lipoprotein particle assembly (GO:0034377)4.34872209
36glycosphingolipid catabolic process (GO:0046479)4.34307713
37nitrogen cycle metabolic process (GO:0071941)4.32422428
38peptide catabolic process (GO:0043171)4.30649153
39transepithelial transport (GO:0070633)4.30159082
40phospholipid efflux (GO:0033700)4.29927495
41intestinal epithelial cell development (GO:0060576)4.27566307
42hormone catabolic process (GO:0042447)4.25726444
43protein-lipid complex assembly (GO:0065005)4.21029639
44drinking behavior (GO:0042756)4.17783424
45very-low-density lipoprotein particle assembly (GO:0034379)4.16931793
46triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.13378568
47maintenance of gastrointestinal epithelium (GO:0030277)4.09203107
48regulation of vitamin metabolic process (GO:0030656)4.02521186
49cholesterol efflux (GO:0033344)4.02228409
50fat-soluble vitamin metabolic process (GO:0006775)4.01553936
51renal system process involved in regulation of blood volume (GO:0001977)3.99142904
52regulation of triglyceride catabolic process (GO:0010896)3.96952736
53glutamine family amino acid biosynthetic process (GO:0009084)3.94960400
54sulfur compound transport (GO:0072348)3.94342825
55regulation of cholesterol esterification (GO:0010872)3.94169363
56antibacterial humoral response (GO:0019731)3.94080687
57positive regulation of triglyceride lipase activity (GO:0061365)3.93775793
58positive regulation of lipoprotein lipase activity (GO:0051006)3.93775793
59diacylglycerol metabolic process (GO:0046339)3.88571246
60cholesterol transport (GO:0030301)3.88347815
61sterol transport (GO:0015918)3.88347815
62antimicrobial humoral response (GO:0019730)3.85027879
63mRNA modification (GO:0016556)3.84753953
64bicarbonate transport (GO:0015701)3.84629095
65alkaloid metabolic process (GO:0009820)3.80676078
66cGMP biosynthetic process (GO:0006182)3.79465986
67vitamin transmembrane transport (GO:0035461)3.75786405
68killing of cells of other organism (GO:0031640)3.72066302
69disruption of cells of other organism (GO:0044364)3.72066302
70citrulline biosynthetic process (GO:0019240)3.70141116
71bile acid metabolic process (GO:0008206)3.69216318
72regulation of cGMP metabolic process (GO:0030823)3.69062126
73negative regulation of cholesterol transport (GO:0032375)3.66475802
74negative regulation of sterol transport (GO:0032372)3.66475802
75cellular response to nitric oxide (GO:0071732)3.65437195
76fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.62959636
77arginine metabolic process (GO:0006525)3.60598805
78sulfate transport (GO:0008272)3.60202656
79positive regulation of cGMP biosynthetic process (GO:0030828)3.58360248
80vitamin transport (GO:0051180)3.57175047
81midgut development (GO:0007494)3.55295612
82* regulation of bile acid biosynthetic process (GO:0070857)3.55161556
83ceramide catabolic process (GO:0046514)3.54750543
84transcytosis (GO:0045056)3.54244141
85O-glycan processing (GO:0016266)3.52955943
86thyroid hormone metabolic process (GO:0042403)3.51651318
87drug transmembrane transport (GO:0006855)3.50807260
88vitamin D metabolic process (GO:0042359)3.50313041
89regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.49899370
90endocrine process (GO:0050886)3.49899370
91regulation of systemic arterial blood pressure by hormone (GO:0001990)3.49899370
92regulation of cholesterol homeostasis (GO:2000188)3.49242932
93sperm capacitation (GO:0048240)3.46954433
94oligosaccharide catabolic process (GO:0009313)3.46016600
95drug transport (GO:0015893)3.45989505
96glycosylceramide metabolic process (GO:0006677)3.45236501
97defense response to fungus (GO:0050832)3.44589627
98sphingomyelin metabolic process (GO:0006684)3.43784891
99heme transport (GO:0015886)3.41403586
100phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.39598706
101omega-hydroxylase P450 pathway (GO:0097267)3.38751212
102receptor guanylyl cyclase signaling pathway (GO:0007168)3.34866353
103negative regulation of digestive system process (GO:0060457)3.32859136
104* cholesterol homeostasis (GO:0042632)3.32778298
105* sterol homeostasis (GO:0055092)3.31968573
106embryonic process involved in female pregnancy (GO:0060136)3.29829270
107vitamin biosynthetic process (GO:0009110)3.29738443
108cytidine metabolic process (GO:0046087)3.28942732
109cytidine catabolic process (GO:0006216)3.28942732
110cytidine deamination (GO:0009972)3.28942732
111positive regulation of lipid catabolic process (GO:0050996)3.28180045
112urate metabolic process (GO:0046415)3.25977284
113striated muscle atrophy (GO:0014891)3.24917467
114glycerol metabolic process (GO:0006071)3.24174677
115positive regulation of glycoprotein biosynthetic process (GO:0010560)3.24015603
116glomerulus development (GO:0032835)3.22111725
117proline biosynthetic process (GO:0006561)3.19456950
118polyol transport (GO:0015791)3.19304191
119regulation of digestive system process (GO:0044058)3.17668064
120homocysteine metabolic process (GO:0050667)3.17571826
121epithelial structure maintenance (GO:0010669)3.15824337
122cellular carbohydrate catabolic process (GO:0044275)3.15690482
123membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.15640924
124nucleobase catabolic process (GO:0046113)3.15074647
125sphingolipid catabolic process (GO:0030149)3.14733229
126phenol-containing compound catabolic process (GO:0019336)3.14268910
127glycoside metabolic process (GO:0016137)3.14258667
128exogenous drug catabolic process (GO:0042738)3.12202094
129regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.11188818
130cellular response to reactive nitrogen species (GO:1902170)3.08738908
131nucleoside diphosphate biosynthetic process (GO:0009133)3.07644833
132regulation of actin nucleation (GO:0051125)3.04855903
133sulfation (GO:0051923)3.04179347
134regulation of systemic arterial blood pressure (GO:0003073)3.03732446
135thrombin receptor signaling pathway (GO:0070493)2.99182209
136fructose metabolic process (GO:0006000)2.92112353
137reverse cholesterol transport (GO:0043691)2.86603846
138positive regulation of fatty acid biosynthetic process (GO:0045723)2.85813199
139positive regulation of T cell differentiation in thymus (GO:0033089)2.84589368
140negative regulation of keratinocyte proliferation (GO:0010839)2.84107985
141purine nucleotide salvage (GO:0032261)2.83071188
142response to hydroperoxide (GO:0033194)2.80450396
143negative regulation of sodium ion transport (GO:0010766)2.79569943
144renal absorption (GO:0070293)2.79405629
145innate immune response in mucosa (GO:0002227)2.79226893
146urea metabolic process (GO:0019627)2.79012661
147urea cycle (GO:0000050)2.79012661
148skeletal muscle adaptation (GO:0043501)2.78796693
149drug metabolic process (GO:0017144)2.78785224
150positive regulation of p38MAPK cascade (GO:1900745)2.77312841
151intestinal absorption (GO:0050892)12.5662829
152intestinal cholesterol absorption (GO:0030299)12.0657969
153angiotensin maturation (GO:0002003)10.9959528

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human7.29490292
2CDX2_20551321_ChIP-Seq_CACO-2_Human5.63093508
3SOX2_27498859_Chip-Seq_STOMACH_Mouse3.74949110
4GATA4_25053715_ChIP-Seq_YYC3_Human3.02218943
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.02077274
6HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.99424680
7GATA6_25053715_ChIP-Seq_YYC3_Human2.74473533
8CDX2_19796622_ChIP-Seq_MESCs_Mouse2.74276519
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.70580968
10SOX2_20726797_ChIP-Seq_SW620_Human2.64612107
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.64512611
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.52294690
13LXR_22158963_ChIP-Seq_LIVER_Mouse2.49558807
14PPARA_22158963_ChIP-Seq_LIVER_Mouse2.44386458
15IRF8_22096565_ChIP-ChIP_GC-B_Human2.21413574
16RXR_22158963_ChIP-Seq_LIVER_Mouse2.16688971
17PPAR_26484153_Chip-Seq_NCI-H1993_Human2.16266337
18CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.06616918
19SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.92810700
20TCF4_18268006_ChIP-ChIP_LS174T_Human1.88136804
21STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.82623718
22IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.81873603
23FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.81319406
24KLF5_25053715_ChIP-Seq_YYC3_Human1.75059317
25GATA1_22025678_ChIP-Seq_K562_Human1.71323282
26ZNF217_24962896_ChIP-Seq_MCF-7_Human1.65542118
27ESR1_15608294_ChIP-ChIP_MCF-7_Human1.63669307
28FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.61623995
29FOXO3_23340844_ChIP-Seq_DLD1_Human1.58547778
30ESR2_21235772_ChIP-Seq_MCF-7_Human1.56899578
31ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.56684415
32CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.56674355
33NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.56447949
34EGR1_23403033_ChIP-Seq_LIVER_Mouse1.53851637
35RUNX1_27514584_Chip-Seq_MCF-7_Human1.50977548
36TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.48861067
37PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.48654957
38BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.44927337
39HNF4A_19822575_ChIP-Seq_HepG2_Human1.41859458
40CTNNB1_20460455_ChIP-Seq_HCT116_Human1.41736246
41RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37353973
42PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.35720642
43FOXA2_19822575_ChIP-Seq_HepG2_Human1.34201331
44AR_21909140_ChIP-Seq_LNCAP_Human1.33686772
45KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.32770588
46KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.32160299
47GATA2_19941826_ChIP-Seq_K562_Human1.31213034
48IRF8_21731497_ChIP-ChIP_J774_Mouse1.31077601
49SRY_22984422_ChIP-ChIP_TESTIS_Rat1.29085070
50GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26985830
51NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.26005789
52VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.23230253
53TP53_16413492_ChIP-PET_HCT116_Human1.23075998
54AHR_22903824_ChIP-Seq_MCF-7_Human1.22880058
55RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.22403325
56FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.17943891
57AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.16870997
58NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.16862923
59SMAD3_21741376_ChIP-Seq_HESCs_Human1.15977460
60VDR_22108803_ChIP-Seq_LS180_Human1.15693505
61RACK7_27058665_Chip-Seq_MCF-7_Human1.15380591
62ZNF263_19887448_ChIP-Seq_K562_Human1.14949482
63ATF3_27146783_Chip-Seq_COLON_Human1.14758736
64ESR1_21235772_ChIP-Seq_MCF-7_Human1.13813702
65STAT6_21828071_ChIP-Seq_BEAS2B_Human1.12749151
66NANOG_20526341_ChIP-Seq_ESCs_Human1.12668604
67SMAD_19615063_ChIP-ChIP_OVARY_Human1.11495998
68FOXM1_26456572_ChIP-Seq_MCF-7_Human1.11270044
69EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.11131130
70PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.07646181
71PIAS1_25552417_ChIP-Seq_VCAP_Human1.05772697
72ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.05054303
73CEBPB_22108803_ChIP-Seq_LS180_Human1.04475805
74ER_23166858_ChIP-Seq_MCF-7_Human1.03655223
75GATA1_19941826_ChIP-Seq_K562_Human1.02081988
76DROSHA_22980978_ChIP-Seq_HELA_Human1.01464950
77EGR1_19032775_ChIP-ChIP_M12_Human1.01249853
78CLOCK_20551151_ChIP-Seq_293T_Human1.00891488
79SOX9_24532713_ChIP-Seq_HFSC_Mouse1.00885725
80MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.98747147
81SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.98186145
82GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.98090351
83PCGF2_27294783_Chip-Seq_NPCs_Mouse0.96734281
84GATA2_22383799_ChIP-Seq_G1ME_Mouse0.96286654
85JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96092633
86NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95794438
87CDX2_22108803_ChIP-Seq_LS180_Human0.94972786
88EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94401387
89SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.94122208
90TP63_23658742_ChIP-Seq_EP156T_Human0.94095190
91FOXA1_25552417_ChIP-Seq_VCAP_Human0.94046149
92SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.93192335
93SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.93192335
94FOXA1_21572438_ChIP-Seq_LNCaP_Human0.93106560
95LXR_22292898_ChIP-Seq_THP-1_Human0.92945457
96ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92823248
97VDR_24787735_ChIP-Seq_THP-1_Human0.91947069
98BCOR_27268052_Chip-Seq_Bcells_Human0.90845039
99ESR1_20079471_ChIP-ChIP_T-47D_Human0.90328189
100BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.90054366
101STAT1_17558387_ChIP-Seq_HELA_Human0.89436236
102CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.89110609
103STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.88677790
104Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.87703580
105JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.87197306
106SALL4_18804426_ChIP-ChIP_XEN_Mouse0.87009401
107ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.86312029
108CJUN_26792858_Chip-Seq_BT549_Human0.85417350
109GATA3_24758297_ChIP-Seq_MCF-7_Human0.85399969
110FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.85390096
111HIF1A_21447827_ChIP-Seq_MCF-7_Human0.85306720
112BCL6_27268052_Chip-Seq_Bcells_Human0.85012410
113BCAT_22108803_ChIP-Seq_LS180_Human0.83361444
114CREB1_26743006_Chip-Seq_LNCaP_Human0.82826797
115TDRD3_21172665_ChIP-Seq_MCF-7_Human0.82634291
116GATA1_26923725_Chip-Seq_HPCs_Mouse0.82355814
117AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.82157653
118P63_26484246_Chip-Seq_KERATINOCYTES_Human0.82036709
119JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.81878252
120FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.81248431
121ARNT_22903824_ChIP-Seq_MCF-7_Human0.81199727
122AR_20517297_ChIP-Seq_VCAP_Human0.79106891
123KAP1_22055183_ChIP-Seq_ESCs_Mouse0.78597749
124GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.77807367
125STAT1_20625510_ChIP-Seq_HELA_Human0.77546471
126TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.77495379
127GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.77424855
128TCF3_18692474_ChIP-Seq_MEFs_Mouse0.76893811
129ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.75725609
130CBP_21632823_ChIP-Seq_H3396_Human0.74784842
131PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.74701589
132SOX2_22085726_ChIP-Seq_NPCs_Mouse0.74341028
133PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.73435501
134GATA2_21666600_ChIP-Seq_HMVEC_Human0.73187270
135SMAD4_21741376_ChIP-Seq_HESCs_Human0.72615448
136CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.72019335
137RXR_22108803_ChIP-Seq_LS180_Human0.68639069

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis9.59934052
2MP0001666_abnormal_nutrient_absorption5.78097999
3MP0004264_abnormal_extraembryonic_tissu4.17000313
4MP0005085_abnormal_gallbladder_physiolo4.09242187
5MP0000462_abnormal_digestive_system3.50000928
6MP0002139_abnormal_hepatobiliary_system3.39428872
7MP0003252_abnormal_bile_duct3.36540343
8MP0010234_abnormal_vibrissa_follicle3.22950424
9MP0003183_abnormal_peptide_metabolism3.16705503
10MP0005365_abnormal_bile_salt2.97698758
11MP0003866_abnormal_defecation2.61231354
12MP0009840_abnormal_foam_cell2.59551610
13MP0008875_abnormal_xenobiotic_pharmacok2.55056367
14MP0003300_gastrointestinal_ulcer2.39579978
15MP0000537_abnormal_urethra_morphology2.27394993
16MP0010329_abnormal_lipoprotein_level2.26577428
17MP0003283_abnormal_digestive_organ2.23008367
18MP0002822_catalepsy2.20349681
19MP0005084_abnormal_gallbladder_morpholo2.16357526
20MP0004147_increased_porphyrin_level2.13583845
21MP0000538_abnormal_urinary_bladder2.10897845
22MP0003878_abnormal_ear_physiology2.06557605
23MP0005377_hearing/vestibular/ear_phenot2.06557605
24MP0005409_darkened_coat_color2.03233338
25MP0004019_abnormal_vitamin_homeostasis2.01467674
26MP0001873_stomach_inflammation1.85521230
27MP0005381_digestive/alimentary_phenotyp1.82860507
28MP0009379_abnormal_foot_pigmentation1.81551703
29MP0001664_abnormal_digestion1.81251620
30MP0004043_abnormal_pH_regulation1.79685818
31MP0001663_abnormal_digestive_system1.74577583
32MP0010155_abnormal_intestine_physiology1.70392353
33MP0010352_gastrointestinal_tract_polyps1.60671279
34MP0000477_abnormal_intestine_morphology1.55917694
35MP0005670_abnormal_white_adipose1.51998798
36MP0000490_abnormal_crypts_of1.42997336
37MP0003705_abnormal_hypodermis_morpholog1.42267043
38MP0009643_abnormal_urine_homeostasis1.37884707
39MP0002089_abnormal_postnatal_growth/wei1.35415903
40MP0005448_abnormal_energy_balance1.33955117
41MP0004782_abnormal_surfactant_physiolog1.33757392
42MP0005332_abnormal_amino_acid1.23980445
43MP0002396_abnormal_hematopoietic_system1.22559623
44MP0002796_impaired_skin_barrier1.20610165
45MP0001501_abnormal_sleep_pattern1.16424800
46MP0006054_spinal_hemorrhage1.08410356
47MP0003191_abnormal_cellular_cholesterol1.07967499
48MP0003806_abnormal_nucleotide_metabolis1.07535896
49MP0002876_abnormal_thyroid_physiology1.06999522
50MP0000465_gastrointestinal_hemorrhage1.02257038
51MP0005167_abnormal_blood-brain_barrier1.00120417
52MP0003868_abnormal_feces_composition0.98663377
53MP0002254_reproductive_system_inflammat0.97110454
54MP0009384_cardiac_valve_regurgitation0.96716249
55MP0009697_abnormal_copulation0.96506665
56MP0005535_abnormal_body_temperature0.96134882
57MP0004270_analgesia0.93835211
58MP0001765_abnormal_ion_homeostasis0.93590165
59MP0002118_abnormal_lipid_homeostasis0.93160045
60MP0000516_abnormal_urinary_system0.91454749
61MP0005367_renal/urinary_system_phenotyp0.91454749
62MP0009780_abnormal_chondrocyte_physiolo0.87804383
63MP0009115_abnormal_fat_cell0.86948120
64MP0000609_abnormal_liver_physiology0.83944951
65MP0009053_abnormal_anal_canal0.82783824
66MP0000230_abnormal_systemic_arterial0.82664355
67MP0004947_skin_inflammation0.81000433
68MP0010678_abnormal_skin_adnexa0.80727612
69MP0004858_abnormal_nervous_system0.80102039
70MP0002971_abnormal_brown_adipose0.78891357
71MP0002098_abnormal_vibrissa_morphology0.78456709
72MP0005501_abnormal_skin_physiology0.77566244
73MP0002136_abnormal_kidney_physiology0.75989264
74MP0001764_abnormal_homeostasis0.73516493
75MP0001849_ear_inflammation0.71771729
76MP0005310_abnormal_salivary_gland0.71486231
77MP0005636_abnormal_mineral_homeostasis0.70981638
78MP0003315_abnormal_perineum_morphology0.69940009
79MP0008004_abnormal_stomach_pH0.69660621
80MP0000467_abnormal_esophagus_morphology0.68553746
81MP0003453_abnormal_keratinocyte_physiol0.68392910
82MP0008872_abnormal_physiological_respon0.66986907
83MP0002277_abnormal_respiratory_mucosa0.65964949
84MP0008469_abnormal_protein_level0.64595414
85MP0001845_abnormal_inflammatory_respons0.64236107
86MP0000470_abnormal_stomach_morphology0.62618285
87MP0005166_decreased_susceptibility_to0.61252549
88MP0006138_congestive_heart_failure0.58121551
89MP0000678_abnormal_parathyroid_gland0.56304129
90MP0005410_abnormal_fertilization0.56100867
91MP0000613_abnormal_salivary_gland0.55235492
92MP0001216_abnormal_epidermal_layer0.55072264
93MP0005334_abnormal_fat_pad0.53876967
94MP0003950_abnormal_plasma_membrane0.53743717
95MP0005395_other_phenotype0.53144057
96MP0003953_abnormal_hormone_level0.52127512
97MP0005319_abnormal_enzyme/_coenzyme0.51989891
98MP0005666_abnormal_adipose_tissue0.51316679
99MP0002138_abnormal_hepatobiliary_system0.51008136
100MP0005266_abnormal_metabolism0.50563642
101MP0001756_abnormal_urination0.50402550
102MP0009764_decreased_sensitivity_to0.49336718
103MP0005584_abnormal_enzyme/coenzyme_acti0.49202323
104MP0003638_abnormal_response/metabolism_0.48371155
105MP0000249_abnormal_blood_vessel0.47862418
106MP0002078_abnormal_glucose_homeostasis0.47426342
107MP0003879_abnormal_hair_cell0.47085510
108MP0009642_abnormal_blood_homeostasis0.47030326
109MP0003941_abnormal_skin_development0.46682282
110MP0002166_altered_tumor_susceptibility0.46145864
111MP0001485_abnormal_pinna_reflex0.45571698
112MP0000566_synostosis0.45420173
113MP0003119_abnormal_digestive_system0.45152356
114MP0003718_maternal_effect0.44963532
115MP0005451_abnormal_body_composition0.44922205
116MP0000604_amyloidosis0.43260757
117MP0002163_abnormal_gland_morphology0.43018321
118MP0005058_abnormal_lysosome_morphology0.41900509
119MP0005376_homeostasis/metabolism_phenot0.41629400
120MP0000681_abnormal_thyroid_gland0.41177653
121MP0001191_abnormal_skin_condition0.40305207
122MP0003329_amyloid_beta_deposits0.39295662
123MP0002896_abnormal_bone_mineralization0.38927056
124MP0008260_abnormal_autophagy0.37654515
125MP0005174_abnormal_tail_pigmentation0.36952037
126MP0000598_abnormal_liver_morphology0.36598115
127MP0001188_hyperpigmentation0.36501140
128MP0002135_abnormal_kidney_morphology0.35657919
129MP0000627_abnormal_mammary_gland0.35309932
130MP0000427_abnormal_hair_cycle0.35129502
131MP0001881_abnormal_mammary_gland0.33940500
132MP0000377_abnormal_hair_follicle0.33717001
133MP0009765_abnormal_xenobiotic_induced0.33539524

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glutamine family amino acid metabolism (HP:0010902)7.38932217
2Acanthocytosis (HP:0001927)6.19382049
3Hypobetalipoproteinemia (HP:0003563)5.95648449
4Conjugated hyperbilirubinemia (HP:0002908)5.82273516
5Malnutrition (HP:0004395)5.40411621
6Hydroxyprolinuria (HP:0003080)5.15822323
7Abnormality of proline metabolism (HP:0010907)5.15822323
8Right ventricular cardiomyopathy (HP:0011663)4.97292686
9Chronic diarrhea (HP:0002028)4.81090427
10Fat malabsorption (HP:0002630)4.54574606
11Autoimmune thrombocytopenia (HP:0001973)4.33280053
12Hyperglycinuria (HP:0003108)3.81661227
13Widely patent fontanelles and sutures (HP:0004492)3.80131854
14Autoimmune hemolytic anemia (HP:0001890)3.76415659
15Poikilocytosis (HP:0004447)3.74348920
16Abnormality of the vitamin B12 metabolism (HP:0004341)3.69946822
17Pigmentary retinal degeneration (HP:0001146)3.63448773
18Cupped ribs (HP:0000887)3.62550668
19Nausea (HP:0002018)3.61973380
20Gastrointestinal dysmotility (HP:0002579)3.49992470
21Abdominal distention (HP:0003270)3.45373568
22Abnormality of vitamin B metabolism (HP:0004340)3.45327229
23Abnormality of urine glucose concentration (HP:0011016)3.28890662
24Glycosuria (HP:0003076)3.28890662
25Facial shape deformation (HP:0011334)3.28095564
26Potter facies (HP:0002009)3.28095564
27Hypolipoproteinemia (HP:0010981)3.27735924
28Rectal prolapse (HP:0002035)3.27678998
29Dehydration (HP:0001944)3.21213817
30Steatorrhea (HP:0002570)3.18303762
31Confusion (HP:0001289)3.03707489
32Decreased circulating renin level (HP:0003351)2.98581176
33Intrahepatic cholestasis (HP:0001406)2.98356952
34Pustule (HP:0200039)2.95446941
35Abnormal biliary tract morphology (HP:0012440)2.93880045
36Systemic lupus erythematosus (HP:0002725)2.90128456
37Progressive sensorineural hearing impairment (HP:0000408)2.88391006
38Congenital sensorineural hearing impairment (HP:0008527)2.85256534
39Abnormality of vitamin metabolism (HP:0100508)2.84213560
40Mildly elevated creatine phosphokinase (HP:0008180)2.83005563
41Alkalosis (HP:0001948)2.81945789
42Hyperuricemia (HP:0002149)2.81937094
43Increased purine levels (HP:0004368)2.81937094
44Nephrolithiasis (HP:0000787)2.79272992
45Posterior subcapsular cataract (HP:0007787)2.77814709
46Abnormality of small intestinal villus morphology (HP:0011472)2.77736421
47Villous atrophy (HP:0011473)2.77736421
48Increased mean platelet volume (HP:0011877)2.75557283
49Abnormality of chloride homeostasis (HP:0011422)2.75020161
50Abnormality of monocarboxylic acid metabolism (HP:0010996)2.74937529
51Abnormality of the gastric mucosa (HP:0004295)2.62836739
52Abnormality of aspartate family amino acid metabolism (HP:0010899)2.61880110
53Delayed epiphyseal ossification (HP:0002663)2.61111402
54Abnormality of serine family amino acid metabolism (HP:0010894)2.60241214
55Abnormality of glycine metabolism (HP:0010895)2.60241214
56Woolly hair (HP:0002224)2.58531844
57Abnormality of the 1st metacarpal (HP:0010009)2.56452843
58Progressive hearing impairment (HP:0001730)2.51842860
59Fragile skin (HP:0001030)2.51272166
60Abnormality of purine metabolism (HP:0004352)2.46902221
61Abnormality of the costochondral junction (HP:0000919)2.44547746
62Hyperphosphaturia (HP:0003109)2.42865913
63Mesangial abnormality (HP:0001966)2.42515053
64Wide cranial sutures (HP:0010537)2.41976680
65Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.40875459
66Flat acetabular roof (HP:0003180)2.37542221
67Abnormal platelet volume (HP:0011876)2.37342618
68Xanthomatosis (HP:0000991)2.36636796
69Abnormal glucose tolerance (HP:0001952)2.36462993
70Thin bony cortex (HP:0002753)2.36293061
71Hypercholesterolemia (HP:0003124)2.36243993
72Hyperactive renin-angiotensin system (HP:0000841)2.35440684
73Abnormality of sulfur amino acid metabolism (HP:0004339)2.30248283
74Subcapsular cataract (HP:0000523)2.28790146
75Epidermoid cyst (HP:0200040)2.27686923
76Reticulocytosis (HP:0001923)2.27625743
77Syncope (HP:0001279)2.27562705
78Male infertility (HP:0003251)2.22638548
79Abnormality of renin-angiotensin system (HP:0000847)2.22034027
80Milia (HP:0001056)2.19549876
81Hypotension (HP:0002615)2.18449931
82Symptomatic seizures (HP:0011145)2.18396482
83Cheilitis (HP:0100825)2.15401408
84Focal segmental glomerulosclerosis (HP:0000097)2.12099654
85Abnormality of dicarboxylic acid metabolism (HP:0010995)2.11584150
86Dicarboxylic aciduria (HP:0003215)2.11584150
87Abnormal urine phosphate concentration (HP:0012599)2.10743213
88Protuberant abdomen (HP:0001538)2.09668799
89Hyperammonemia (HP:0001987)2.06343446
90Ventricular fibrillation (HP:0001663)2.05949348
91Alopecia of scalp (HP:0002293)2.05731710
92Hyperphosphatemia (HP:0002905)2.04930963
93Renal tubular dysfunction (HP:0000124)2.04725483
94Cerebral palsy (HP:0100021)2.03682240
95Hypophosphatemic rickets (HP:0004912)2.03647781
96Metabolic acidosis (HP:0001942)2.02407417
97Increased IgE level (HP:0003212)2.02389331
98Urethral obstruction (HP:0000796)2.02267766
99Renal tubular acidosis (HP:0001947)2.01769412
100Ileus (HP:0002595)10.1170168
101Osteomalacia (HP:0002749)1.99336164
102Gout (HP:0001997)1.99046835
103Cone-rod dystrophy (HP:0000548)1.98945883
104Glomerulosclerosis (HP:0000096)1.97928285
105Proximal tubulopathy (HP:0000114)1.96697883
106Generalized aminoaciduria (HP:0002909)1.95915997
107Abnormality of nucleobase metabolism (HP:0010932)1.95545565
108Hemorrhage of the eye (HP:0011885)1.95317442
109Hypophosphatemia (HP:0002148)1.93429283
110Megaloblastic anemia (HP:0001889)1.92877101
111Irritability (HP:0000737)1.92070318
112Ureteral stenosis (HP:0000071)1.91893020
113Abnormal tarsal ossification (HP:0008369)1.90559406
114Goiter (HP:0000853)1.89570640
115Abnormal pancreas size (HP:0012094)1.89095676
116Biliary tract neoplasm (HP:0100574)1.86514673
117Hyperparathyroidism (HP:0000843)1.85427827
118Metabolic alkalosis (HP:0200114)1.85128662
119Eczematoid dermatitis (HP:0000976)1.84616078
120Pancreatitis (HP:0001733)1.84510187
121Hypocalcemia (HP:0002901)1.82888194
122Abnormality of pyrimidine metabolism (HP:0004353)1.81258708
123Ureteral obstruction (HP:0006000)1.79984691
124Exocrine pancreatic insufficiency (HP:0001738)1.79829112
125Metaphyseal irregularity (HP:0003025)1.77638078
126Palpitations (HP:0001962)1.76763971
127Lethargy (HP:0001254)1.75372004
128Enlarged epiphyses (HP:0010580)1.74998010
129Abnormal enzyme/coenzyme activity (HP:0012379)1.74020114
130Abnormality of the distal phalanx of the thumb (HP:0009617)1.72128035
131Myopathic facies (HP:0002058)1.71774211
132Abnormality of alkaline phosphatase activity (HP:0004379)1.71177095
133Multiple lipomas (HP:0001012)1.70823648
134Petechiae (HP:0000967)1.69257051
135Plantar hyperkeratosis (HP:0007556)1.69178518
136Prolonged QT interval (HP:0001657)1.67672179
137Growth hormone excess (HP:0000845)1.67152295
138Hyperbilirubinemia (HP:0002904)1.67038330
139Gingivitis (HP:0000230)1.63343942
140Pili torti (HP:0003777)1.63290138

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B8.81746636
2LMTK26.86768493
3FRK6.85675172
4MST44.96181937
5NME14.44566279
6MST1R3.59111574
7PRKG23.30003924
8RIPK12.82044961
9AKT32.74001405
10GRK62.56559768
11EPHA22.46458885
12NUAK12.22823605
13MAP3K102.15474780
14PTK61.96747851
15TAOK31.92144178
16MAP2K21.86585323
17EPHB21.68670553
18FGFR41.67911616
19MAP3K121.66216126
20NEK61.56126912
21MAP3K21.50721328
22TNIK1.41785893
23PIK3CA1.21591808
24MET1.19007061
25ERN11.18826226
26LATS11.17990047
27STK391.14261491
28STK101.13792764
29TTK1.10581357
30TRIB31.07229448
31DMPK1.07137768
32DDR21.02581518
33PIK3CG1.01774338
34ERBB21.00028706
35PIM11.00023791
36CASK0.99574820
37TESK10.97594512
38EPHB10.97131059
39MYLK0.95614554
40FGFR30.95381052
41WNK40.93936178
42PTK20.91605438
43TYK20.91355861
44PRKCI0.89825452
45MAPKAPK30.87587797
46PASK0.86050768
47EPHA40.83105069
48PRKAA20.81893784
49EPHA30.81203695
50MAP2K60.79512454
51CSF1R0.78782919
52OXSR10.77105329
53RET0.75694337
54FER0.74855801
55MAP3K70.72682910
56BMX0.71374314
57MATK0.70451754
58RIPK40.69146285
59PBK0.68945655
60PINK10.67816169
61RPS6KB20.66875631
62TAOK10.65182969
63BTK0.62406887
64MUSK0.61456530
65PKN20.61084832
66MAP3K80.60890501
67MAP3K110.60316525
68STK240.59467169
69TEC0.59442339
70GRK10.58009559
71BMPR20.57057464
72MELK0.53485114
73NLK0.53143756
74MAP2K10.51923970
75INSRR0.50454546
76MAP4K10.50317311
77STK30.48393521
78PRKAA10.45842927
79PDK20.45334442
80MAPK110.44711776
81PAK40.44223494
82ROCK10.42885187
83RPS6KB10.42551118
84PAK30.42355834
85AURKB0.41463175
86PDPK10.40774183
87SCYL20.38008142
88MAPKAPK20.37456754
89CDK120.37226105
90LRRK20.37220460
91SIK10.36905708
92TESK20.36504956
93IRAK10.35500005
94DYRK1B0.35472627
95IKBKE0.35100721
96CSK0.33473364
97KSR20.32676894
98NEK10.32608979
99STK110.32077722
100TBK10.31540172
101BCR0.31299350
102KIT0.30858916
103JAK20.30627972
104MAP3K30.29872444
105PRKCA0.29855023
106SYK0.29569401
107MAP3K10.29016417
108PAK20.27873290
109CAMK2D0.27669068
110JAK10.27605919
111MAP3K90.27505427
112ICK0.27216280
113RPS6KA20.26976599
114SRC0.26608536
115ERBB40.25109541
116EEF2K0.25059342
117CHUK0.23606578
118PRKCQ0.22977274
119PDK10.22773320
120PRKACA0.22754875
121CAMK1D0.22383102
122PDGFRA0.21395921
123CAMKK10.20769084
124STK38L0.20414821
125CSNK1A10.20380019
126FYN0.20267262
127PRKACG0.19684523
128IRAK30.19491003
129BMPR1B0.17406927
130PRKCZ0.17316734
131PRKCD0.16523254
132GSK3A0.16464845
133AKT20.15565758
134CDC42BPA0.15186532
135FGR0.13902544
136ITK0.11651311
137PAK10.11186245
138PDK40.10705838
139PDK30.10705838
140CAMK2B0.10451442
141CAMK2G0.09815166

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049755.41575063
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005245.21776624
3Renin-angiotensin system_Homo sapiens_hsa046144.42608386
4Mineral absorption_Homo sapiens_hsa049784.10769047
5Vitamin digestion and absorption_Homo sapiens_hsa049773.73713121
6Galactose metabolism_Homo sapiens_hsa000522.90635202
7Carbohydrate digestion and absorption_Homo sapiens_hsa049732.80226938
8Caffeine metabolism_Homo sapiens_hsa002322.79537033
9Sulfur metabolism_Homo sapiens_hsa009202.75188623
10Bile secretion_Homo sapiens_hsa049762.60657539
11Starch and sucrose metabolism_Homo sapiens_hsa005002.50753529
12Protein digestion and absorption_Homo sapiens_hsa049742.45866615
13Maturity onset diabetes of the young_Homo sapiens_hsa049502.44812165
14Fructose and mannose metabolism_Homo sapiens_hsa000511.97753010
15Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.96528117
16Folate biosynthesis_Homo sapiens_hsa007901.86756489
17Histidine metabolism_Homo sapiens_hsa003401.76129542
18Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.75876592
19Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.68140487
20Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.66952537
21PPAR signaling pathway_Homo sapiens_hsa033201.43463145
22Nitrogen metabolism_Homo sapiens_hsa009101.41505642
23Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.40393203
24Glycerolipid metabolism_Homo sapiens_hsa005611.28949652
25Tryptophan metabolism_Homo sapiens_hsa003801.27287647
26ABC transporters_Homo sapiens_hsa020101.25463545
27Arginine biosynthesis_Homo sapiens_hsa002201.21610277
28Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.20300234
29Glutathione metabolism_Homo sapiens_hsa004801.19094643
30Cyanoamino acid metabolism_Homo sapiens_hsa004601.18692770
31Pentose and glucuronate interconversions_Homo sapiens_hsa000401.11723793
32Sphingolipid metabolism_Homo sapiens_hsa006001.09275636
33Fatty acid degradation_Homo sapiens_hsa000711.08155248
34Arginine and proline metabolism_Homo sapiens_hsa003300.99683150
35Phenylalanine metabolism_Homo sapiens_hsa003600.96623766
36Thyroid hormone synthesis_Homo sapiens_hsa049180.93105247
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88452486
38Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.87291505
39Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86743528
40Tight junction_Homo sapiens_hsa045300.81185963
41Asthma_Homo sapiens_hsa053100.72266346
42Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72109715
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.70832466
44beta-Alanine metabolism_Homo sapiens_hsa004100.65960872
45Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.64425528
46Pancreatic secretion_Homo sapiens_hsa049720.63617820
47Gastric acid secretion_Homo sapiens_hsa049710.61648853
48Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61509178
49Type II diabetes mellitus_Homo sapiens_hsa049300.61251557
502-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.60167945
51Glycerophospholipid metabolism_Homo sapiens_hsa005640.56257494
52Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.55122779
53Carbon metabolism_Homo sapiens_hsa012000.53653715
54Pyruvate metabolism_Homo sapiens_hsa006200.53101745
55alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.51587303
56Drug metabolism - other enzymes_Homo sapiens_hsa009830.44005358
57Selenocompound metabolism_Homo sapiens_hsa004500.43741111
58Butanoate metabolism_Homo sapiens_hsa006500.43301445
59Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42993269
60Salmonella infection_Homo sapiens_hsa051320.41553101
61Pentose phosphate pathway_Homo sapiens_hsa000300.41051407
62Tyrosine metabolism_Homo sapiens_hsa003500.40651857
63Allograft rejection_Homo sapiens_hsa053300.40047627
64Fatty acid metabolism_Homo sapiens_hsa012120.38822112
65Insulin secretion_Homo sapiens_hsa049110.38316720
66Leukocyte transendothelial migration_Homo sapiens_hsa046700.38075887
67Adherens junction_Homo sapiens_hsa045200.37979309
68Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.36824083
69Phosphatidylinositol signaling system_Homo sapiens_hsa040700.36821193
70Autoimmune thyroid disease_Homo sapiens_hsa053200.35807965
71Lysine degradation_Homo sapiens_hsa003100.35739246
72Salivary secretion_Homo sapiens_hsa049700.35649169
73Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.35259122
74Graft-versus-host disease_Homo sapiens_hsa053320.32647697
75Chemical carcinogenesis_Homo sapiens_hsa052040.31726826
76Retinol metabolism_Homo sapiens_hsa008300.30752615
77Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30657495
78Adipocytokine signaling pathway_Homo sapiens_hsa049200.30599812
79Intestinal immune network for IgA production_Homo sapiens_hsa046720.30372642
80Bladder cancer_Homo sapiens_hsa052190.29810896
81Inositol phosphate metabolism_Homo sapiens_hsa005620.29545200
82Arachidonic acid metabolism_Homo sapiens_hsa005900.26213700
83Peroxisome_Homo sapiens_hsa041460.25972564
84Metabolic pathways_Homo sapiens_hsa011000.25119060
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.24944474
86Hepatitis C_Homo sapiens_hsa051600.24178814
87African trypanosomiasis_Homo sapiens_hsa051430.23173190
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.22344557
89Staphylococcus aureus infection_Homo sapiens_hsa051500.22139367
90Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.20789416
91Linoleic acid metabolism_Homo sapiens_hsa005910.20163427
92Vibrio cholerae infection_Homo sapiens_hsa051100.19531006
93Propanoate metabolism_Homo sapiens_hsa006400.18433012
94GnRH signaling pathway_Homo sapiens_hsa049120.18163782
95Type I diabetes mellitus_Homo sapiens_hsa049400.16738989
96Serotonergic synapse_Homo sapiens_hsa047260.16676362
97Ovarian steroidogenesis_Homo sapiens_hsa049130.15551738
98Steroid hormone biosynthesis_Homo sapiens_hsa001400.14607603
99Other glycan degradation_Homo sapiens_hsa005110.14129900
100Thyroid cancer_Homo sapiens_hsa052160.14127398
101Renin secretion_Homo sapiens_hsa049240.14002875
102Steroid biosynthesis_Homo sapiens_hsa001000.13766750
103Glucagon signaling pathway_Homo sapiens_hsa049220.13565988
104Cocaine addiction_Homo sapiens_hsa050300.12164622
105Fatty acid biosynthesis_Homo sapiens_hsa000610.12077265
106Hematopoietic cell lineage_Homo sapiens_hsa046400.11391925
107Insulin resistance_Homo sapiens_hsa049310.10765964
108Ether lipid metabolism_Homo sapiens_hsa005650.10737600
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.10552991
110Choline metabolism in cancer_Homo sapiens_hsa052310.09862168
111Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.09025764
112Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.08854465
113Gap junction_Homo sapiens_hsa045400.07467510
114Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.06797531
115AMPK signaling pathway_Homo sapiens_hsa041520.06522982
116Antigen processing and presentation_Homo sapiens_hsa046120.05383183
117Aldosterone synthesis and secretion_Homo sapiens_hsa049250.04308806
118Biosynthesis of amino acids_Homo sapiens_hsa012300.03422076
119Sulfur relay system_Homo sapiens_hsa041220.02970308
120Amoebiasis_Homo sapiens_hsa051460.02738279
121Systemic lupus erythematosus_Homo sapiens_hsa053220.01587236
122Alzheimers disease_Homo sapiens_hsa050100.01365985
123Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.00188434
124Vascular smooth muscle contraction_Homo sapiens_hsa04270-0.0405479
125Fatty acid elongation_Homo sapiens_hsa00062-0.0134383
126Amphetamine addiction_Homo sapiens_hsa05031-0.0081961

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