MALT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.07466614
2positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.96159317
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.94743119
4modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.83914844
5positive regulation by organism of defense response of other organism involved in symbiotic interact4.83914844
6modulation by symbiont of host immune response (GO:0052553)4.83914844
7positive regulation by symbiont of host defense response (GO:0052509)4.83914844
8modulation by symbiont of host defense response (GO:0052031)4.83914844
9modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.83914844
10NIK/NF-kappaB signaling (GO:0038061)4.72360885
11regulation of interleukin-12 biosynthetic process (GO:0045075)4.69286075
12regulation of gamma-delta T cell activation (GO:0046643)4.35007148
13neutrophil activation involved in immune response (GO:0002283)4.25779579
14regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)4.25079667
15antigen processing and presentation of endogenous antigen (GO:0019883)4.16609595
16response to peptidoglycan (GO:0032494)4.08782778
17myeloid dendritic cell differentiation (GO:0043011)4.08639871
18regulation of gamma-delta T cell differentiation (GO:0045586)4.03162667
19positive regulation of humoral immune response (GO:0002922)3.99869637
20response to muramyl dipeptide (GO:0032495)3.98876654
21antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.92575363
22antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.92575363
23interferon-gamma production (GO:0032609)3.85491210
24positive regulation of interferon-alpha production (GO:0032727)3.83388127
25myeloid dendritic cell activation (GO:0001773)3.82693428
26regulation of interleukin-2 biosynthetic process (GO:0045076)3.82198814
27leukocyte aggregation (GO:0070486)3.77736184
28regulation of interferon-alpha production (GO:0032647)3.75723373
29negative regulation of cell killing (GO:0031342)3.73965342
30negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.73965342
31T cell migration (GO:0072678)3.70613429
32macrophage activation involved in immune response (GO:0002281)3.63539378
33regulation of T-helper 1 cell differentiation (GO:0045625)3.63394446
34regulation of alpha-beta T cell proliferation (GO:0046640)3.63108522
35positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.59600545
36negative regulation of interleukin-12 production (GO:0032695)3.57865990
37negative thymic T cell selection (GO:0045060)3.55435760
38granulocyte activation (GO:0036230)3.54631699
39* positive regulation of interleukin-2 production (GO:0032743)3.52388902
40regulation of dendritic cell antigen processing and presentation (GO:0002604)3.52124974
41negative T cell selection (GO:0043383)3.49661431
42regulation of B cell receptor signaling pathway (GO:0050855)3.49051046
43regulation of interferon-beta biosynthetic process (GO:0045357)3.49022484
44neutrophil activation (GO:0042119)3.48899733
45defense response to protozoan (GO:0042832)3.47311992
46positive regulation of interleukin-12 production (GO:0032735)3.46249210
47B cell homeostasis (GO:0001782)3.45410294
48CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.44165371
49positive regulation of natural killer cell differentiation (GO:0032825)3.43494595
50interferon-gamma-mediated signaling pathway (GO:0060333)3.43291351
51JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.42477869
52positive thymic T cell selection (GO:0045059)3.41897893
53immunoglobulin mediated immune response (GO:0016064)3.39339991
54response to interleukin-15 (GO:0070672)3.38923794
55positive regulation of B cell differentiation (GO:0045579)3.38149900
56positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.37955208
57lipopolysaccharide-mediated signaling pathway (GO:0031663)3.35915095
58positive T cell selection (GO:0043368)3.35338620
59positive regulation of immunoglobulin mediated immune response (GO:0002891)3.32919153
60positive regulation of B cell mediated immunity (GO:0002714)3.32919153
61T cell selection (GO:0045058)3.32547528
62positive regulation of alpha-beta T cell proliferation (GO:0046641)3.32492365
63phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.30561890
64regulation of B cell differentiation (GO:0045577)3.30124915
65positive regulation of antigen processing and presentation (GO:0002579)3.28735709
66response to type I interferon (GO:0034340)3.28533584
67positive regulation of cytokine biosynthetic process (GO:0042108)3.26755909
68cellular response to type I interferon (GO:0071357)3.26539495
69type I interferon signaling pathway (GO:0060337)3.26539495
70cellular extravasation (GO:0045123)3.22693225
71thymic T cell selection (GO:0045061)3.22341449
72response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.20807211
73response to host immune response (GO:0052572)3.20807211
74regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.18786494
75regulation of chronic inflammatory response (GO:0002676)3.18652240
76positive regulation of cellular amide metabolic process (GO:0034250)3.18651916
77regulation of interleukin-12 production (GO:0032655)3.18472289
78positive regulation of chemokine biosynthetic process (GO:0045080)3.16905799
79hepatocyte apoptotic process (GO:0097284)3.16660547
80natural killer cell mediated cytotoxicity (GO:0042267)3.15035481
81natural killer cell mediated immunity (GO:0002228)3.15035481
82response to protozoan (GO:0001562)3.13984399
83positive regulation of isotype switching (GO:0045830)3.12194527
84respiratory burst (GO:0045730)3.12066844
85cellular response to ethanol (GO:0071361)3.10292430
86positive regulation of interferon-beta production (GO:0032728)3.07868678
87positive regulation of interleukin-10 production (GO:0032733)3.07648899
88tolerance induction (GO:0002507)3.06953231
89* regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.06243716
90monoubiquitinated protein deubiquitination (GO:0035520)3.01335460
91cellular response to interleukin-15 (GO:0071350)3.00063714
92positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.99487753
93regulation of fibroblast apoptotic process (GO:2000269)2.99435284
94dendritic cell differentiation (GO:0097028)2.99168910
95regulation of immunoglobulin secretion (GO:0051023)2.98956028
96B cell receptor signaling pathway (GO:0050853)2.97334517
97myeloid cell activation involved in immune response (GO:0002275)2.95896651
98germinal center formation (GO:0002467)2.94988375
99leukocyte cell-cell adhesion (GO:0007159)2.93492209
100response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.92281601
101response to host (GO:0075136)2.92281601
102response to host defenses (GO:0052200)2.92281601
103necroptotic process (GO:0070266)2.91635046
104positive regulation of heat generation (GO:0031652)2.90804574
105negative regulation of B cell proliferation (GO:0030889)2.89272069
106positive regulation of interleukin-17 production (GO:0032740)2.86803960
107regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.86592000
108I-kappaB phosphorylation (GO:0007252)2.86412026
109regulation of T cell tolerance induction (GO:0002664)2.86060104
110B cell proliferation (GO:0042100)2.85163885
111positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.84288218
112negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.84149152
113negative regulation of T-helper cell differentiation (GO:0045623)2.84149152
114positive regulation of type 2 immune response (GO:0002830)2.83557613
115negative regulation of T cell mediated immunity (GO:0002710)2.82812789
116regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.82277912
117regulation of antigen processing and presentation (GO:0002577)2.81721687
118cellular response to zinc ion (GO:0071294)2.81051079
119detection of other organism (GO:0098543)2.80124945
120activated T cell proliferation (GO:0050798)2.79972380
121positive regulation of granulocyte differentiation (GO:0030854)2.72084441
122nuclear pore complex assembly (GO:0051292)2.71850320
123T cell lineage commitment (GO:0002360)2.70402499
124cytoplasmic mRNA processing body assembly (GO:0033962)2.69591962
125* antigen receptor-mediated signaling pathway (GO:0050851)2.69565236
126regulation of B cell proliferation (GO:0030888)2.68442034
127histone H3-K36 demethylation (GO:0070544)2.67828886
128regulation of MHC class I biosynthetic process (GO:0045343)2.67601259
129negative regulation of DNA repair (GO:0045738)2.66171797
130T cell costimulation (GO:0031295)2.66145093
131regulation of regulatory T cell differentiation (GO:0045589)2.64820934
132detection of molecule of bacterial origin (GO:0032490)2.64793023
133antigen processing and presentation via MHC class Ib (GO:0002475)2.64789149
134lymphocyte costimulation (GO:0031294)2.63521688
135T cell homeostasis (GO:0043029)2.61336742
136CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.61191629
137T-helper cell differentiation (GO:0042093)2.61191629
138alpha-beta T cell differentiation (GO:0046632)2.59174661
139dendritic cell migration (GO:0036336)2.57489316
140regulation of histone H3-K27 methylation (GO:0061085)2.57249813
141necrotic cell death (GO:0070265)2.57074433
142negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.55649459
143regulation of necroptotic process (GO:0060544)2.54761661
144detection of bacterium (GO:0016045)2.54009601

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.48691340
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.96452357
3IRF8_21731497_ChIP-ChIP_J774_Mouse5.64878073
4BP1_19119308_ChIP-ChIP_Hs578T_Human5.24538715
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.80221596
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.44866627
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.99238011
8* IRF8_27001747_Chip-Seq_BMDM_Mouse3.84487779
9SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.60994633
10* STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.60646865
11EGR1_19374776_ChIP-ChIP_THP-1_Human3.56417428
12NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.32005113
13* MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.25621187
14STAT4_19710469_ChIP-ChIP_TH1__Mouse3.08293760
15RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.07089718
16* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.90161352
17* SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.85427106
18Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.79840022
19* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.74682524
20RUNX_20019798_ChIP-Seq_JUKART_Human2.61956238
21MYB_26560356_Chip-Seq_TH2_Human2.46824771
22* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.38335096
23STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.18978781
24MAF_26560356_Chip-Seq_TH1_Human2.13327159
25* MYB_26560356_Chip-Seq_TH1_Human2.10428734
26SPI1_23547873_ChIP-Seq_NB4_Human2.05566419
27BRD4_27068464_Chip-Seq_AML-cells_Mouse2.03347368
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.89609178
29VDR_24763502_ChIP-Seq_THP-1_Human1.88070602
30SMAD_19615063_ChIP-ChIP_OVARY_Human1.84109474
31MYC_22102868_ChIP-Seq_BL_Human1.82379070
32* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.80939319
33PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.80550876
34VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.77291026
35VDR_21846776_ChIP-Seq_THP-1_Human1.77104288
36PU_27001747_Chip-Seq_BMDM_Mouse1.73117958
37SCL_19346495_ChIP-Seq_HPC-7_Human1.72982222
38RUNX1_22412390_ChIP-Seq_EML_Mouse1.67121545
39E2F7_22180533_ChIP-Seq_HELA_Human1.65462544
40GATA3_27048872_Chip-Seq_THYMUS_Human1.62320651
41NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.62119153
42UTX_26944678_Chip-Seq_JUKART_Human1.60259751
43SPI1_23127762_ChIP-Seq_K562_Human1.60224908
44VDR_24787735_ChIP-Seq_THP-1_Human1.54135370
45RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.50021703
46E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.48206450
47TCF7_22412390_ChIP-Seq_EML_Mouse1.44609724
48PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.41988115
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.41645509
50STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.41371441
51CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.37584435
52TP53_16413492_ChIP-PET_HCT116_Human1.37545555
53CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.37175322
54* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.36821408
55GATA1_22025678_ChIP-Seq_K562_Human1.36608630
56GATA3_26560356_Chip-Seq_TH2_Human1.29907332
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.29250607
58FLI1_27457419_Chip-Seq_LIVER_Mouse1.28205078
59PCGF2_27294783_Chip-Seq_NPCs_Mouse1.27113384
60MAF_26560356_Chip-Seq_TH2_Human1.26123032
61MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.26001058
62KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.24430477
63GATA2_22383799_ChIP-Seq_G1ME_Mouse1.20580806
64NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.20527688
65* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.19642335
66FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.18406064
67PCGF2_27294783_Chip-Seq_ESCs_Mouse1.17538953
68CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.16902984
69* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13209479
70* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.09909590
71ZNF217_24962896_ChIP-Seq_MCF-7_Human1.09262204
72* BRD4_25478319_ChIP-Seq_HGPS_Human1.07953691
73KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.07467445
74RBPJ_22232070_ChIP-Seq_NCS_Mouse1.06799161
75FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.06097034
76KDM2B_26808549_Chip-Seq_SUP-B15_Human1.03843223
77CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03097448
78LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.02765102
79KDM2B_26808549_Chip-Seq_DND41_Human1.02359856
80KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.01867970
81FOXM1_23109430_ChIP-Seq_U2OS_Human0.99352532
82PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99345658
83AR_21572438_ChIP-Seq_LNCaP_Human0.98754309
84FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97743532
85THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.95948551
86CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.95792865
87GATA2_21666600_ChIP-Seq_HMVEC_Human0.95658797
88SALL4_18804426_ChIP-ChIP_XEN_Mouse0.95137474
89CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.94201539
90PPAR_26484153_Chip-Seq_NCI-H1993_Human0.92418428
91SUZ12_27294783_Chip-Seq_NPCs_Mouse0.91833775
92TP63_17297297_ChIP-ChIP_HaCaT_Human0.91548553
93CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.91480683
94* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91174614
95TP63_23658742_ChIP-Seq_EP156T_Human0.89833593
96ELK3_25401928_ChIP-Seq_HUVEC_Human0.87201300
97BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.86531616
98TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.86431268
99AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.86221457
100NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.86019314
101NRF2_20460467_ChIP-Seq_MEFs_Mouse0.86019314
102* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.85824689
103RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.85566023
104FOXA2_19822575_ChIP-Seq_HepG2_Human0.84697442
105WT1_19549856_ChIP-ChIP_CCG9911_Human0.84536993
106ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.81884213
107EZH2_27294783_Chip-Seq_NPCs_Mouse0.80771770
108* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.80732239
109SOX9_24532713_ChIP-Seq_HFSC_Mouse0.80550536
110NFE2_27457419_Chip-Seq_LIVER_Mouse0.80072231
111AHR_22903824_ChIP-Seq_MCF-7_Human0.78291862
112TFEB_21752829_ChIP-Seq_HELA_Human0.77180465
113CJUN_26792858_Chip-Seq_BT549_Human0.75974338
114OCT4_21477851_ChIP-Seq_ESCs_Mouse0.75569637
115RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.74498235
116* GATA3_26560356_Chip-Seq_TH1_Human0.74211729
117* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.73595815
118* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.73595815
119SMRT_27268052_Chip-Seq_Bcells_Human0.73303269
120GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.73259489
121CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.73065313
122GATA1_19941827_ChIP-Seq_MEL_Mouse0.71623783
123* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.70898447
124FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.69971456
125GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.69813523
126LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.68300455
127FOXO3_23340844_ChIP-Seq_DLD1_Human0.67066515
128* PU.1_20513432_ChIP-Seq_Bcells_Mouse0.66314093
129TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.65790345
130* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.64741950
131SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.63774163
132TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.63336704
133SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.62358873
134GATA2_19941826_ChIP-Seq_K562_Human0.61099702
135NCOR1_26117541_ChIP-Seq_K562_Human0.59219201
136JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.58838118
137GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.58424762
138JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.55194542

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.49100185
2MP0003436_decreased_susceptibility_to3.75151280
3MP0001790_abnormal_immune_system3.58451815
4MP0005387_immune_system_phenotype3.58451815
5MP0009785_altered_susceptibility_to3.54966914
6MP0003303_peritoneal_inflammation3.43699133
7MP0005000_abnormal_immune_tolerance3.39171351
8MP0002148_abnormal_hypersensitivity_rea3.22294930
9MP0005671_abnormal_response_to3.21603446
10* MP0001800_abnormal_humoral_immune3.20774744
11* MP0002452_abnormal_antigen_presenting2.97308827
12* MP0000685_abnormal_immune_system2.93467842
13MP0005025_abnormal_response_to2.91567150
14MP0002419_abnormal_innate_immunity2.88476135
15* MP0002723_abnormal_immune_serum2.84648547
16MP0004510_myositis2.74996835
17MP0006082_CNS_inflammation2.57687513
18* MP0001819_abnormal_immune_cell2.56715784
19* MP0002420_abnormal_adaptive_immunity2.56605126
20MP0003724_increased_susceptibility_to2.41809578
21MP0001853_heart_inflammation2.28482355
22MP0002405_respiratory_system_inflammati2.27150263
23MP0003763_abnormal_thymus_physiology2.20348710
24MP0004947_skin_inflammation2.15258107
25MP0002006_tumorigenesis2.13886874
26MP0010155_abnormal_intestine_physiology2.08019374
27* MP0002398_abnormal_bone_marrow2.06579261
28* MP0000716_abnormal_immune_system2.00776988
29MP0003300_gastrointestinal_ulcer1.98142310
30MP0001845_abnormal_inflammatory_respons1.94110113
31MP0002166_altered_tumor_susceptibility1.92537315
32MP0005464_abnormal_platelet_physiology1.82280750
33MP0001533_abnormal_skeleton_physiology1.74718084
34MP0009333_abnormal_splenocyte_physiolog1.73704816
35MP0003448_altered_tumor_morphology1.73699490
36* MP0000689_abnormal_spleen_morphology1.66654998
37MP0009764_decreased_sensitivity_to1.64903714
38MP0005310_abnormal_salivary_gland1.63947768
39MP0001873_stomach_inflammation1.61869374
40* MP0002429_abnormal_blood_cell1.60305237
41MP0000569_abnormal_digit_pigmentation1.59356924
42MP0002722_abnormal_immune_system1.58290910
43MP0002138_abnormal_hepatobiliary_system1.56693387
44MP0001348_abnormal_lacrimal_gland1.56319126
45MP0009278_abnormal_bone_marrow1.51416956
46MP0008469_abnormal_protein_level1.47488375
47MP0002933_joint_inflammation1.43600072
48MP0003866_abnormal_defecation1.37799698
49MP0003950_abnormal_plasma_membrane1.35557870
50MP0010234_abnormal_vibrissa_follicle1.34848177
51MP0000858_altered_metastatic_potential1.34683759
52MP0002254_reproductive_system_inflammat1.33966229
53MP0005397_hematopoietic_system_phenotyp1.32820170
54MP0001545_abnormal_hematopoietic_system1.32820170
55MP0002998_abnormal_bone_remodeling1.30679912
56MP0010352_gastrointestinal_tract_polyps1.28555010
57MP0005058_abnormal_lysosome_morphology1.27551950
58MP0002396_abnormal_hematopoietic_system1.26986981
59MP0003172_abnormal_lysosome_physiology1.25117603
60MP0003221_abnormal_cardiomyocyte_apopto1.23865438
61MP0005076_abnormal_cell_differentiation1.23850304
62MP0000703_abnormal_thymus_morphology1.23326393
63MP0008961_abnormal_basal_metabolism1.21336182
64MP0003252_abnormal_bile_duct1.20636322
65MP0004808_abnormal_hematopoietic_stem1.15616740
66MP0006054_spinal_hemorrhage1.08982235
67MP0000604_amyloidosis1.02314144
68MP0002277_abnormal_respiratory_mucosa1.00918706
69MP0003453_abnormal_keratinocyte_physiol1.00236784
70MP0003828_pulmonary_edema0.99947178
71MP0000343_altered_response_to0.97290772
72MP0005174_abnormal_tail_pigmentation0.97005006
73MP0008057_abnormal_DNA_replication0.96975196
74MP0005166_decreased_susceptibility_to0.96329739
75MP0003091_abnormal_cell_migration0.95945745
76MP0004883_abnormal_blood_vessel0.94560695
77MP0010307_abnormal_tumor_latency0.91252889
78MP0000371_diluted_coat_color0.89806565
79MP0001851_eye_inflammation0.89186339
80MP0003075_altered_response_to0.88706787
81MP0004264_abnormal_extraembryonic_tissu0.87349632
82MP0008260_abnormal_autophagy0.86923907
83MP0005167_abnormal_blood-brain_barrier0.82171161
84MP0009763_increased_sensitivity_to0.82001465
85MP0003183_abnormal_peptide_metabolism0.81846817
86MP0000465_gastrointestinal_hemorrhage0.80813008
87MP0000490_abnormal_crypts_of0.77416037
88MP0010678_abnormal_skin_adnexa0.76882433
89MP0005390_skeleton_phenotype0.75603643
90MP0002168_other_aberrant_phenotype0.73907576
91MP0001216_abnormal_epidermal_layer0.73530017
92MP0004782_abnormal_surfactant_physiolog0.72326138
93MP0003566_abnormal_cell_adhesion0.71421080
94MP0009115_abnormal_fat_cell0.71369995
95MP0005621_abnormal_cell_physiology0.69750028
96MP0000015_abnormal_ear_pigmentation0.68956297
97MP0000249_abnormal_blood_vessel0.68345501
98MP0002019_abnormal_tumor_incidence0.66039526
99MP0003705_abnormal_hypodermis_morpholog0.65969289
100MP0002136_abnormal_kidney_physiology0.65909469
101MP0003868_abnormal_feces_composition0.62992001
102MP0000767_abnormal_smooth_muscle0.62457014
103MP0004185_abnormal_adipocyte_glucose0.61709221
104MP0003795_abnormal_bone_structure0.61051664
105MP0002163_abnormal_gland_morphology0.60606290
106MP0002928_abnormal_bile_duct0.60581341
107MP0003191_abnormal_cellular_cholesterol0.60025898
108MP0005164_abnormal_response_to0.57495586
109MP0001663_abnormal_digestive_system0.57054586
110MP0005275_abnormal_skin_tensile0.56432143
111MP0003890_abnormal_embryonic-extraembry0.56327796
112MP0005023_abnormal_wound_healing0.55550326
113MP0001915_intracranial_hemorrhage0.55126236
114MP0002009_preneoplasia0.54776145
115MP0000627_abnormal_mammary_gland0.54200565
116MP0001881_abnormal_mammary_gland0.53992028
117MP0005451_abnormal_body_composition0.52033489
118MP0009765_abnormal_xenobiotic_induced0.51470208
119MP0002877_abnormal_melanocyte_morpholog0.51392248
120MP0004381_abnormal_hair_follicle0.51131759
121MP0003045_fibrosis0.50714768
122MP0001191_abnormal_skin_condition0.49007733

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.56508892
2Recurrent abscess formation (HP:0002722)6.09304392
3Recurrent bacterial skin infections (HP:0005406)5.58033539
4Recurrent fungal infections (HP:0002841)5.00373284
5Stomatitis (HP:0010280)4.94180098
6Recurrent gram-negative bacterial infections (HP:0005420)4.68125243
7Retrobulbar optic neuritis (HP:0100654)4.65282421
8Optic neuritis (HP:0100653)4.65282421
9* Mediastinal lymphadenopathy (HP:0100721)4.62362239
10Myositis (HP:0100614)4.51378784
11Elevated erythrocyte sedimentation rate (HP:0003565)4.35378321
12Abnormality of macrophages (HP:0004311)4.32878101
13Orchitis (HP:0100796)4.29591027
14Chronic mucocutaneous candidiasis (HP:0002728)4.19378139
15Recurrent cutaneous fungal infections (HP:0011370)4.19378139
16Vasculitis (HP:0002633)4.11415926
17Recurrent skin infections (HP:0001581)4.09701634
18* Recurrent viral infections (HP:0004429)3.99922101
19Gingivitis (HP:0000230)3.65190058
20Autoimmune thrombocytopenia (HP:0001973)3.63931135
21T lymphocytopenia (HP:0005403)3.62439937
22Abnormality of T cell number (HP:0011839)3.62145811
23Chronic obstructive pulmonary disease (HP:0006510)3.61355138
24Obstructive lung disease (HP:0006536)3.61355138
25Autoimmune hemolytic anemia (HP:0001890)3.35063480
26Meningitis (HP:0001287)3.34917310
27Arterial thrombosis (HP:0004420)3.29231902
28Gastrointestinal stroma tumor (HP:0100723)3.21099094
29Chronic otitis media (HP:0000389)3.18289158
30* Pulmonary infiltrates (HP:0002113)3.15037438
31Periodontitis (HP:0000704)3.13731438
32Abnormal delayed hypersensitivity skin test (HP:0002963)3.11275863
33Cellulitis (HP:0100658)3.09631421
34Hemoptysis (HP:0002105)3.07423534
35Chronic diarrhea (HP:0002028)3.05752158
36Recurrent bronchitis (HP:0002837)3.03307406
37Pustule (HP:0200039)3.02679348
38Inflammation of the large intestine (HP:0002037)3.00665262
39Increased IgM level (HP:0003496)2.99349723
40Panhypogammaglobulinemia (HP:0003139)2.95679988
41Abnormality of T cells (HP:0002843)2.94107870
42Gastrointestinal infarctions (HP:0005244)2.92985916
43IgA deficiency (HP:0002720)2.91589131
44Interstitial pulmonary disease (HP:0006530)2.87669091
45Agammaglobulinemia (HP:0004432)2.87534130
46Myocardial infarction (HP:0001658)2.85879942
47Gastrointestinal inflammation (HP:0004386)2.82918326
48Leukocytosis (HP:0001974)2.78312965
49Keratoconjunctivitis sicca (HP:0001097)2.77324539
50Viral hepatitis (HP:0006562)2.73531112
51Colitis (HP:0002583)2.73335035
52Subacute progressive viral hepatitis (HP:0006572)2.69428806
53Basal ganglia calcification (HP:0002135)2.66849096
54Gingival bleeding (HP:0000225)2.64119402
55Lymphopenia (HP:0001888)2.63610547
56Syringomyelia (HP:0003396)2.63044975
57Spinal cord lesions (HP:0100561)2.63044975
58Abnormality of the fingertips (HP:0001211)2.62734957
59Osteomyelitis (HP:0002754)2.60029005
60Abnormality of cells of the lymphoid lineage (HP:0012140)2.56192570
61Keratoconjunctivitis (HP:0001096)2.55941206
62Nasal polyposis (HP:0100582)2.55348345
63IgM deficiency (HP:0002850)2.54380613
64Prostate neoplasm (HP:0100787)2.49092717
65Emphysema (HP:0002097)2.48678492
66Cheilitis (HP:0100825)2.46656169
67Recurrent pneumonia (HP:0006532)2.46336269
68Abnormality of B cell number (HP:0010975)2.46036149
69Hypergammaglobulinemia (HP:0010702)2.45384868
70Thick nail (HP:0001805)2.45231668
71Chest pain (HP:0100749)2.44383821
72B lymphocytopenia (HP:0010976)2.44356118
73Increased IgE level (HP:0003212)2.44309619
74Joint swelling (HP:0001386)2.39755616
75Abnormality of T cell physiology (HP:0011840)2.37895521
76Eosinophilia (HP:0001880)2.36586763
77Encephalitis (HP:0002383)2.34233368
78Restrictive lung disease (HP:0002091)2.30912539
79Vacuolated lymphocytes (HP:0001922)2.30730990
80Recurrent sinusitis (HP:0011108)2.26994455
81Thrombocytosis (HP:0001894)2.26941305
82IgG deficiency (HP:0004315)2.24872788
83Papilloma (HP:0012740)2.24594512
84Verrucae (HP:0200043)2.24594512
85Hypoplasia of the thymus (HP:0000778)2.24576873
86Premature loss of primary teeth (HP:0006323)2.24420776
87Urticaria (HP:0001025)2.23781872
88Arthralgia (HP:0002829)2.23296759
89Hematochezia (HP:0002573)2.23219335
90Increased cerebral lipofuscin (HP:0011813)2.23010389
91Aortic dissection (HP:0002647)2.21526074
92Combined immunodeficiency (HP:0005387)2.20915714
93Severe combined immunodeficiency (HP:0004430)2.18946255
94Recurrent lower respiratory tract infections (HP:0002783)2.17040811
95Skin ulcer (HP:0200042)2.16995155
96Fatigue (HP:0012378)2.16409190
97Basal cell carcinoma (HP:0002671)2.15705625
98Abnormality of the prostate (HP:0008775)2.12841175
99Abnormality of the nasal mucosa (HP:0000433)2.11952894
100Increased neuronal autofluorescent lipopigment (HP:0002074)2.10508374
101Thyroiditis (HP:0100646)2.09359247
102Osteolytic defects of the hand bones (HP:0009699)2.07137313
103Osteolytic defects of the phalanges of the hand (HP:0009771)2.07137313
104Abnormality of eosinophils (HP:0001879)2.06725975
105Papilledema (HP:0001085)2.06274986
106Leukopenia (HP:0001882)2.05149638
107Porencephaly (HP:0002132)2.04355371
108Aortic aneurysm (HP:0004942)2.03948968
109Granulocytopenia (HP:0001913)2.02353861
110Neoplasm of the tracheobronchial system (HP:0100552)2.01410541
111Gangrene (HP:0100758)2.00952135
112Fair hair (HP:0002286)1.98503817
113Hepatitis (HP:0012115)1.98451246
114Spontaneous hematomas (HP:0007420)1.95825463
115Abnormality of the endocardium (HP:0004306)1.94046928
116Abnormal foot bone ossification (HP:0010675)1.94031294
117Epistaxis (HP:0000421)1.93090850
118Lymphoma (HP:0002665)1.92492480
119Volvulus (HP:0002580)1.91358479
120Peritonitis (HP:0002586)1.90244702
121Abnormality of the lumbar spine (HP:0100712)1.89681356
122Acute hepatic failure (HP:0006554)1.87035468
123Delayed closure of the anterior fontanelle (HP:0001476)1.86927461
124Arterial tortuosity (HP:0005116)1.85912796
125Thoracolumbar scoliosis (HP:0002944)1.81968686
126Acrocyanosis (HP:0001063)1.81106719
127Dislocated radial head (HP:0003083)1.79602436
128Low anterior hairline (HP:0000294)1.79307582
129Bicuspid aortic valve (HP:0001647)1.79277919
130Spondylolisthesis (HP:0003302)1.78210308
131Xerostomia (HP:0000217)1.75674721
132Abnormality of incisor morphology (HP:0011063)1.74833966
133Prominent nose (HP:0000448)1.73930506

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K144.78665388
2MAP4K14.22789043
3JAK33.69523466
4RIPK43.68023310
5TXK3.67132040
6TYK23.20979869
7TBK13.01912341
8PRPF4B2.85391359
9IKBKE2.78334898
10BLK2.72243553
11IKBKB2.68185410
12IRAK32.60794523
13MAP3K132.58096094
14IRAK42.48575750
15JAK12.41293592
16CHUK2.05042451
17ZAP701.93849251
18AKT31.87413478
19EIF2AK31.86104076
20CSK1.63732390
21FRK1.58159077
22KIT1.54818074
23SYK1.51661958
24PKN21.50505440
25ACVR1B1.49683986
26BTK1.48473915
27CDK121.44111682
28ITK1.42919909
29HCK1.42411807
30LCK1.41779942
31STK101.41473102
32FGFR31.34205802
33TEC1.30542392
34MAP3K101.29783980
35FGFR41.29574912
36EPHB11.27035013
37PIM11.24092711
38WNK11.22404454
39RPS6KA41.17406719
40JAK21.17367499
41PIM21.16252504
42CSF1R1.14128968
43MARK31.11125059
44STK38L1.08700211
45PIK3CG1.07968518
46SIK21.06273407
47LYN1.04221589
48PBK1.02399005
49LATS11.00464946
50ERN11.00138850
51TNIK0.97845695
52MST40.95193399
53CAMKK20.95107658
54CDC42BPA0.92089784
55GRK60.90783653
56EPHA30.90728935
57TAF10.89861308
58FES0.89035716
59SIK30.88847389
60SGK20.88712972
61BMPR20.86504890
62IRAK10.84580712
63PDGFRA0.83453444
64NLK0.81928407
65NEK90.81044471
66FGFR10.80251930
67PRKCQ0.79191258
68MAPK70.77500844
69MAPK110.76267625
70TAOK30.75298208
71LRRK20.71380327
72STK390.69455532
73PTK60.69365108
74TTN0.67926061
75PASK0.67483189
76SMG10.67182528
77STK40.66945092
78CLK10.66734621
79FGR0.65696228
80YES10.64477812
81MAP3K50.63325971
82BMX0.63153793
83ABL10.62995565
84NME20.62062498
85EGFR0.61742586
86TRPM70.60626877
87TRIB30.60037768
88EIF2AK20.57761574
89STK240.57578066
90PDGFRB0.57462341
91MAP2K30.54943945
92BRSK20.53588539
93STK30.50335753
94IRAK20.48888666
95ERBB30.48260400
96TGFBR20.47281125
97ALK0.46508156
98BRD40.45920071
99TGFBR10.45244517
100MAP3K20.45043544
101MKNK20.44817581
102GRK70.43583888
103MAP3K110.43282070
104CDK60.42952976
105CDK40.40346512
106PDK10.40144442
107PRKCD0.38604649
108MAP2K60.38305179
109DMPK0.37851828
110RIPK10.37795019
111MAPKAPK20.37256203
112TNK20.36529189
113FLT30.36332792
114MST1R0.36031761
115MELK0.35791355
116EEF2K0.35384566
117MAP3K70.34118812
118PKN10.33391803
119INSR0.33196656
120MATK0.32094680
121PRKCH0.30088133
122NUAK10.29710537
123IGF1R0.27047355
124FYN0.26726739
125SIK10.25688969
126RPS6KA50.24949091
127SGK30.23638729
128CAMK1D0.23122725
129CDK90.21957187
130MAP3K30.21869105
131GSK3A0.21740852

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053323.19798897
2* NF-kappa B signaling pathway_Homo sapiens_hsa040643.11905292
3Leishmaniasis_Homo sapiens_hsa051403.11815604
4Allograft rejection_Homo sapiens_hsa053302.93371596
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.72236702
6NOD-like receptor signaling pathway_Homo sapiens_hsa046212.51894471
7Measles_Homo sapiens_hsa051622.50118842
8Toll-like receptor signaling pathway_Homo sapiens_hsa046202.49150232
9Osteoclast differentiation_Homo sapiens_hsa043802.42378029
10Primary immunodeficiency_Homo sapiens_hsa053402.38731186
11RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.24956753
12Intestinal immune network for IgA production_Homo sapiens_hsa046722.18994394
13Type I diabetes mellitus_Homo sapiens_hsa049402.16603141
14Legionellosis_Homo sapiens_hsa051342.13440623
15Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.12405023
16TNF signaling pathway_Homo sapiens_hsa046682.07455963
17Asthma_Homo sapiens_hsa053102.05100964
18* B cell receptor signaling pathway_Homo sapiens_hsa046622.04822747
19Hematopoietic cell lineage_Homo sapiens_hsa046401.99547239
20Malaria_Homo sapiens_hsa051441.93690550
21Staphylococcus aureus infection_Homo sapiens_hsa051501.84310346
22Influenza A_Homo sapiens_hsa051641.81300393
23* Tuberculosis_Homo sapiens_hsa051521.80242941
24* T cell receptor signaling pathway_Homo sapiens_hsa046601.74725344
25Rheumatoid arthritis_Homo sapiens_hsa053231.73149762
26Herpes simplex infection_Homo sapiens_hsa051681.71635608
27Pertussis_Homo sapiens_hsa051331.70748574
28Autoimmune thyroid disease_Homo sapiens_hsa053201.70281187
29Jak-STAT signaling pathway_Homo sapiens_hsa046301.70092823
30Toxoplasmosis_Homo sapiens_hsa051451.69548658
31Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.67594411
32Antigen processing and presentation_Homo sapiens_hsa046121.51912480
33Chemokine signaling pathway_Homo sapiens_hsa040621.46351140
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.44713551
35Apoptosis_Homo sapiens_hsa042101.41831131
36Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.39456179
37African trypanosomiasis_Homo sapiens_hsa051431.37412552
38Viral myocarditis_Homo sapiens_hsa054161.34384771
39Hepatitis B_Homo sapiens_hsa051611.28808008
40Salmonella infection_Homo sapiens_hsa051321.26726807
41Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.26238325
42Shigellosis_Homo sapiens_hsa051311.23520365
43Acute myeloid leukemia_Homo sapiens_hsa052211.16543135
44AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.14567533
45Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.14325739
46Hepatitis C_Homo sapiens_hsa051601.11388311
47Chronic myeloid leukemia_Homo sapiens_hsa052200.97484946
48Epstein-Barr virus infection_Homo sapiens_hsa051690.96666665
49Leukocyte transendothelial migration_Homo sapiens_hsa046700.92813044
50Prolactin signaling pathway_Homo sapiens_hsa049170.90118746
51Endometrial cancer_Homo sapiens_hsa052130.89297630
52Phagosome_Homo sapiens_hsa041450.89186806
53Small cell lung cancer_Homo sapiens_hsa052220.79501326
54Pancreatic cancer_Homo sapiens_hsa052120.77601331
55Adipocytokine signaling pathway_Homo sapiens_hsa049200.76628692
56Lysosome_Homo sapiens_hsa041420.75952299
57Neurotrophin signaling pathway_Homo sapiens_hsa047220.75262280
58Viral carcinogenesis_Homo sapiens_hsa052030.73631384
59Adherens junction_Homo sapiens_hsa045200.72289542
60HTLV-I infection_Homo sapiens_hsa051660.70567671
61Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70207681
62Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.68845471
63Amoebiasis_Homo sapiens_hsa051460.67053158
64ErbB signaling pathway_Homo sapiens_hsa040120.61038307
65Type II diabetes mellitus_Homo sapiens_hsa049300.59673516
66Choline metabolism in cancer_Homo sapiens_hsa052310.58513436
67Platelet activation_Homo sapiens_hsa046110.57929179
68Glioma_Homo sapiens_hsa052140.54742823
69Focal adhesion_Homo sapiens_hsa045100.54613497
70Non-homologous end-joining_Homo sapiens_hsa034500.54238781
71HIF-1 signaling pathway_Homo sapiens_hsa040660.53163056
72Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52960239
73Thyroid cancer_Homo sapiens_hsa052160.52633162
74Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51207756
75Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.48395478
76Insulin resistance_Homo sapiens_hsa049310.48279562
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.45342447
78Dorso-ventral axis formation_Homo sapiens_hsa043200.44747996
79Circadian rhythm_Homo sapiens_hsa047100.44650446
80VEGF signaling pathway_Homo sapiens_hsa043700.44147663
81MicroRNAs in cancer_Homo sapiens_hsa052060.43983695
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.42695227
83Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.42474653
84Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42457458
85Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.42406989
86GnRH signaling pathway_Homo sapiens_hsa049120.41584311
87Other glycan degradation_Homo sapiens_hsa005110.40118133
88TGF-beta signaling pathway_Homo sapiens_hsa043500.39341310
89Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.38642748
90Notch signaling pathway_Homo sapiens_hsa043300.38010852
91MAPK signaling pathway_Homo sapiens_hsa040100.37412686
92Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.35636267
93Melanoma_Homo sapiens_hsa052180.35506397
94FoxO signaling pathway_Homo sapiens_hsa040680.35258288
95mTOR signaling pathway_Homo sapiens_hsa041500.34730677
96Glycosaminoglycan degradation_Homo sapiens_hsa005310.34001612
97Renal cell carcinoma_Homo sapiens_hsa052110.33091723
98Prostate cancer_Homo sapiens_hsa052150.31752559
99Proteoglycans in cancer_Homo sapiens_hsa052050.31399286
100Regulation of actin cytoskeleton_Homo sapiens_hsa048100.30153162
101Carbohydrate digestion and absorption_Homo sapiens_hsa049730.28988558
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27301310
103Non-small cell lung cancer_Homo sapiens_hsa052230.26995994
104p53 signaling pathway_Homo sapiens_hsa041150.26704935
105Colorectal cancer_Homo sapiens_hsa052100.23030493
106Phosphatidylinositol signaling system_Homo sapiens_hsa040700.23006981
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.21674505
108Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.20563911
109Endocytosis_Homo sapiens_hsa041440.19447395
110Inositol phosphate metabolism_Homo sapiens_hsa005620.18804661
111Prion diseases_Homo sapiens_hsa050200.17323202
112Thyroid hormone signaling pathway_Homo sapiens_hsa049190.14155889
113Pathways in cancer_Homo sapiens_hsa052000.12128954
114Systemic lupus erythematosus_Homo sapiens_hsa053220.11555286
115Phospholipase D signaling pathway_Homo sapiens_hsa040720.10313711

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