MAMSTR

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1muscle filament sliding (GO:0030049)8.56164514
2actin-myosin filament sliding (GO:0033275)8.56164514
3regulation of skeletal muscle contraction (GO:0014819)7.74011389
4actin-mediated cell contraction (GO:0070252)7.19759500
5skeletal muscle contraction (GO:0003009)7.08356801
6creatine metabolic process (GO:0006600)6.54262011
7sarcoplasmic reticulum calcium ion transport (GO:0070296)6.35598265
8sarcomere organization (GO:0045214)5.92757698
9plasma membrane repair (GO:0001778)5.83597996
10actin filament-based movement (GO:0030048)5.46162651
11myofibril assembly (GO:0030239)5.37517201
12positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.35153731
13regulation of relaxation of muscle (GO:1901077)5.12360331
14skeletal muscle adaptation (GO:0043501)5.08968732
15regulation of cell communication by electrical coupling (GO:0010649)5.06484742
16skeletal muscle fiber development (GO:0048741)5.05527067
17response to stimulus involved in regulation of muscle adaptation (GO:0014874)5.05127424
18striated muscle contraction (GO:0006941)4.93863204
19regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.80257552
20negative regulation of potassium ion transmembrane transporter activity (GO:1901017)4.57955384
21glucan biosynthetic process (GO:0009250)4.57382639
22glycogen biosynthetic process (GO:0005978)4.57382639
23cardiac myofibril assembly (GO:0055003)4.54035655
24glucan catabolic process (GO:0009251)4.53937696
25myotube cell development (GO:0014904)4.52773495
26striated muscle atrophy (GO:0014891)4.46305780
27striated muscle adaptation (GO:0014888)4.44895089
28regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.37977248
29NADH metabolic process (GO:0006734)4.32467898
30response to inactivity (GO:0014854)4.30538821
31muscle organ morphogenesis (GO:0048644)4.29754869
32cellular polysaccharide catabolic process (GO:0044247)4.22790124
33muscle atrophy (GO:0014889)4.17434927
34muscle adaptation (GO:0043500)4.13807973
35actomyosin structure organization (GO:0031032)4.07092954
36neuronal action potential propagation (GO:0019227)4.04106709
37regulation of actin filament-based movement (GO:1903115)3.95511391
38muscle cell fate commitment (GO:0042693)3.94820037
39regulation of podosome assembly (GO:0071801)3.90978418
40cardiac muscle hypertrophy (GO:0003300)3.90795611
41striated muscle hypertrophy (GO:0014897)3.90537366
42gluconeogenesis (GO:0006094)3.86290737
43muscle contraction (GO:0006936)3.85636542
44positive regulation of myoblast differentiation (GO:0045663)3.85471078
45positive regulation of mitochondrial calcium ion concentration (GO:0051561)3.75560496
46polysaccharide catabolic process (GO:0000272)3.75388355
47ubiquinone biosynthetic process (GO:0006744)3.74749040
48muscle hypertrophy (GO:0014896)3.72677634
49negative regulation of potassium ion transmembrane transport (GO:1901380)3.71505915
50muscle system process (GO:0003012)3.67709822
51negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.65877540
52regulation of membrane repolarization (GO:0060306)3.63671036
53cardiac muscle adaptation (GO:0014887)3.63257053
54cardiac muscle hypertrophy in response to stress (GO:0014898)3.63257053
55muscle hypertrophy in response to stress (GO:0003299)3.63257053
56negative regulation of calcium ion transmembrane transport (GO:1903170)3.62863564
57negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.62863564
58cardiac muscle contraction (GO:0060048)3.59462853
59fructose metabolic process (GO:0006000)3.58483820
60negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.57837225
61regulation of sarcomere organization (GO:0060297)3.56550725
62tricarboxylic acid cycle (GO:0006099)3.56113070
63response to activity (GO:0014823)3.52997214
64negative regulation of peptidyl-lysine acetylation (GO:2000757)3.51509236
65muscle fiber development (GO:0048747)3.50333810
662-oxoglutarate metabolic process (GO:0006103)3.47348097
67muscle cell cellular homeostasis (GO:0046716)3.46829203
68regulation of striated muscle contraction (GO:0006942)3.45884104
69negative regulation of protein localization to cell surface (GO:2000009)3.45250388
70ubiquinone metabolic process (GO:0006743)3.43267211
71hexose biosynthetic process (GO:0019319)3.43112835
72regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.38735629
73muscle organ development (GO:0007517)3.35707835
74glycogen metabolic process (GO:0005977)3.32090971
75muscle structure development (GO:0061061)3.30969720
76cardiac muscle cell development (GO:0055013)3.30953708
77negative regulation of B cell apoptotic process (GO:0002903)3.28564343
78skeletal muscle tissue development (GO:0007519)3.27521835
79regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.25216821
80heart process (GO:0003015)3.24793358
81heart contraction (GO:0060047)3.24793358
82regulation of myoblast differentiation (GO:0045661)3.24262562
83glucan metabolic process (GO:0044042)3.22962506
84cellular glucan metabolic process (GO:0006073)3.22962506
85positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.22724253
86cardiac muscle tissue morphogenesis (GO:0055008)3.22411378
87skeletal muscle tissue regeneration (GO:0043403)3.20993210
88myoblast fusion (GO:0007520)3.17753663
89otic vesicle formation (GO:0030916)3.17217919
90regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.16993328
91oxidative phosphorylation (GO:0006119)3.16566214
92cardiac cell development (GO:0055006)3.16067454
93response to muscle activity (GO:0014850)3.13606018
94negative regulation of protein acetylation (GO:1901984)3.12642027
95striated muscle cell development (GO:0055002)3.12593033
96negative regulation of muscle contraction (GO:0045932)3.12038674
97negative regulation of muscle hypertrophy (GO:0014741)3.11698306
98relaxation of muscle (GO:0090075)3.09275815
99* positive regulation of myotube differentiation (GO:0010831)3.06654742
100regulation of skeletal muscle cell differentiation (GO:2001014)2.94713043
101cardiac muscle cell action potential (GO:0086001)2.94707760
102regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.94486120
103negative regulation of histone acetylation (GO:0035067)2.92016115
104cardiac muscle cell action potential involved in contraction (GO:0086002)2.91456423
105syncytium formation by plasma membrane fusion (GO:0000768)2.91300899
106negative regulation of cytosolic calcium ion concentration (GO:0051481)2.90965255
107negative regulation of potassium ion transport (GO:0043267)2.89911586
108regulation of calcium ion transmembrane transport (GO:1903169)2.88208419
109regulation of calcium ion transmembrane transporter activity (GO:1901019)2.88208419
110oxygen transport (GO:0015671)2.84789164
111neuromuscular synaptic transmission (GO:0007274)2.84354298
112myotube differentiation (GO:0014902)2.78322968
113membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.76899939
114cardiac conduction (GO:0061337)2.76453071
115striated muscle tissue development (GO:0014706)2.74237308
116regulation of muscle system process (GO:0090257)2.72509195
117regulation of cardiac muscle cell differentiation (GO:2000725)2.70715176
118pyrimidine ribonucleoside catabolic process (GO:0046133)2.70544493
119syncytium formation (GO:0006949)2.68318926
120regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.68232181
121adult heart development (GO:0007512)2.66975520
122muscle tissue morphogenesis (GO:0060415)2.66228883
123dendritic cell chemotaxis (GO:0002407)2.65762066
124regulation of cardioblast proliferation (GO:0003264)2.64618388
125regulation of secondary heart field cardioblast proliferation (GO:0003266)2.64618388
126regulation of skeletal muscle fiber development (GO:0048742)2.63904555
127polyketide metabolic process (GO:0030638)2.63697339
128doxorubicin metabolic process (GO:0044598)2.63697339
129daunorubicin metabolic process (GO:0044597)2.63697339
130glycogen catabolic process (GO:0005980)2.63167308
131regulation of muscle contraction (GO:0006937)2.62924576
132regulation of heart rate by cardiac conduction (GO:0086091)2.62219826
133ventricular cardiac muscle cell action potential (GO:0086005)2.62047583
134muscle cell development (GO:0055001)2.61487613

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human4.30352897
2RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.31572403
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.27049077
4ESRRB_18555785_ChIP-Seq_MESCs_Mouse3.12208606
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.01877875
6EZH2_22144423_ChIP-Seq_EOC_Human2.95088324
7TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.78609178
8TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.69776874
9GBX2_23144817_ChIP-Seq_PC3_Human2.69250683
10BCL3_23251550_ChIP-Seq_MUSCLE_Mouse2.61541146
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.61436193
12SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.48267739
13* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse2.41473700
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.28647552
15MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.22695049
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.19687376
17RARG_19884340_ChIP-ChIP_MEFs_Mouse2.15299329
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.10810031
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.09656120
20SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.09620123
21SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.07378976
22JARID2_20075857_ChIP-Seq_MESCs_Mouse2.05135809
23RNF2_18974828_ChIP-Seq_MESCs_Mouse2.04723641
24EZH2_18974828_ChIP-Seq_MESCs_Mouse2.04723641
25EP300_21415370_ChIP-Seq_HL-1_Mouse2.03637546
26JARID2_20064375_ChIP-Seq_MESCs_Mouse2.02979102
27CTCF_27219007_Chip-Seq_Bcells_Human1.97752774
28ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.95742722
29SMAD_19615063_ChIP-ChIP_OVARY_Human1.88935629
30RNF2_27304074_Chip-Seq_ESCs_Mouse1.83812930
31CDX2_19796622_ChIP-Seq_MESCs_Mouse1.83329042
32SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.82495538
33EZH2_27294783_Chip-Seq_ESCs_Mouse1.81028967
34RBPJ_22232070_ChIP-Seq_NCS_Mouse1.80466279
35MTF2_20144788_ChIP-Seq_MESCs_Mouse1.80318432
36ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.79127242
37SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.78906816
38DROSHA_22980978_ChIP-Seq_HELA_Human1.78216378
39CBX2_27304074_Chip-Seq_ESCs_Mouse1.77328330
40THAP11_20581084_ChIP-Seq_MESCs_Mouse1.74697857
41TRIM28_21343339_ChIP-Seq_HEK293_Human1.73109166
42AR_21572438_ChIP-Seq_LNCaP_Human1.71858086
43ZFP57_27257070_Chip-Seq_ESCs_Mouse1.69484986
44NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.69387951
45ZNF263_19887448_ChIP-Seq_K562_Human1.67571880
46SUZ12_27294783_Chip-Seq_ESCs_Mouse1.66937546
47TP53_18474530_ChIP-ChIP_U2OS_Human1.66918021
48SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.63895629
49GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.61875729
50NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.59724452
51GATA4_21415370_ChIP-Seq_HL-1_Mouse1.55018195
52PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.54285370
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.51694778
54PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49503217
55TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.48185198
56SMC3_22415368_ChIP-Seq_MEFs_Mouse1.47888814
57BMI1_23680149_ChIP-Seq_NPCS_Mouse1.47364125
58VDR_22108803_ChIP-Seq_LS180_Human1.44517188
59ESR1_20079471_ChIP-ChIP_T-47D_Human1.44137407
60ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.43950141
61NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.43486885
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41808231
63SRF_21415370_ChIP-Seq_HL-1_Mouse1.38180340
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.32039503
65SMAD4_21799915_ChIP-Seq_A2780_Human1.31829548
66P300_19829295_ChIP-Seq_ESCs_Human1.31237485
67PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.30080082
68ZFP281_18757296_ChIP-ChIP_E14_Mouse1.29669214
69CTCF_21964334_ChIP-Seq_BJAB-B_Human1.29627245
70* TBX20_22328084_ChIP-Seq_HEART_Mouse1.29573620
71* TBX20_22080862_ChIP-Seq_HEART_Mouse1.29573620
72ERG_21242973_ChIP-ChIP_JURKAT_Human1.26407132
73POU3F2_20337985_ChIP-ChIP_501MEL_Human1.26297979
74ZNF217_24962896_ChIP-Seq_MCF-7_Human1.26080837
75TP53_16413492_ChIP-PET_HCT116_Human1.25961639
76PCGF2_27294783_Chip-Seq_ESCs_Mouse1.25917969
77TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25622551
78* LXR_22292898_ChIP-Seq_THP-1_Human1.24817819
79TP53_20018659_ChIP-ChIP_R1E_Mouse1.23189795
80SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.21597846
81CTCF_21964334_Chip-Seq_Bcells_Human1.21040444
82PIAS1_25552417_ChIP-Seq_VCAP_Human1.20848016
83ESR1_21235772_ChIP-Seq_MCF-7_Human1.20528536
84EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.20282555
85CJUN_26792858_Chip-Seq_BT549_Human1.17795507
86SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.17259156
87MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.17200136
88SMAD3_21741376_ChIP-Seq_EPCs_Human1.16941951
89AR_25329375_ChIP-Seq_VCAP_Human1.15595049
90THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.15344670
91CTCF_26484167_Chip-Seq_Bcells_Mouse1.14470445
92SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.14227203
93CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.14053687
94YY1_22570637_ChIP-Seq_MALME-3M_Human1.13687326
95NFIB_24661679_ChIP-Seq_LUNG_Mouse1.11908511
96TET1_21451524_ChIP-Seq_MESCs_Mouse1.11786824
97SA1_27219007_Chip-Seq_Bcells_Human1.11312698
98DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.10831882
99RAD21_21589869_ChIP-Seq_MESCs_Mouse1.09782206
100FUS_26573619_Chip-Seq_HEK293_Human1.09524300
101OCT4_20526341_ChIP-Seq_ESCs_Human1.09070961
102SOX2_21211035_ChIP-Seq_LN229_Gbm1.08579626
103DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08549354
104CTBP2_25329375_ChIP-Seq_LNCAP_Human1.07247189
105SUZ12_27294783_Chip-Seq_NPCs_Mouse1.07037421
106CTBP1_25329375_ChIP-Seq_LNCAP_Human1.06654040
107* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.06328777
108UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06088421
109FLI1_27457419_Chip-Seq_LIVER_Mouse1.05781028
110NRF2_20460467_ChIP-Seq_MEFs_Mouse1.05291602
111NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.05291602
112SMAD4_21741376_ChIP-Seq_HESCs_Human1.04372449
113VDR_24787735_ChIP-Seq_THP-1_Human1.03311472
114STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.03113305
115TCF4_18268006_ChIP-ChIP_LS174T_Human1.02061219
116ER_23166858_ChIP-Seq_MCF-7_Human1.01796098
117IGF1R_20145208_ChIP-Seq_DFB_Human1.01337371
118TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00852728
119POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00852728
120MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.00793856
121TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00284142
122RXR_22108803_ChIP-Seq_LS180_Human1.00190905
123CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.99927100
124YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99741308
125PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99550643
126CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.99337920
127RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.99013210
128SMAD3_21741376_ChIP-Seq_HESCs_Human0.98424372
129TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.98081423
130WT1_19549856_ChIP-ChIP_CCG9911_Human0.97948785
131SRY_22984422_ChIP-ChIP_TESTIS_Rat0.97894729
132NR3C1_23031785_ChIP-Seq_PC12_Mouse0.97788522
133PPARA_22158963_ChIP-Seq_LIVER_Mouse0.97531745
134NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97371923
135P68_20966046_ChIP-Seq_HELA_Human0.97246323
136BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.97149452
137CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.97005344
138EZH2_27294783_Chip-Seq_NPCs_Mouse0.96415948
139E2F1_18555785_Chip-Seq_ESCs_Mouse0.96393546
140SA1_27219007_Chip-Seq_ERYTHROID_Human0.96378004
141TAF15_26573619_Chip-Seq_HEK293_Human0.96216386
142NANOG_18555785_Chip-Seq_ESCs_Mouse0.95956110
143TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.95910716
144SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95540281
145E2F1_20622854_ChIP-Seq_HELA_Human0.95377572
146P53_22387025_ChIP-Seq_ESCs_Mouse0.95300581
147* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.93685343
148PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92878211
149RING1B_27294783_Chip-Seq_ESCs_Mouse0.92560434
150FOXP1_21924763_ChIP-Seq_HESCs_Human0.92471119
151SPI1_20517297_ChIP-Seq_HL60_Human0.92016632
152ARNT_22903824_ChIP-Seq_MCF-7_Human0.91361041
153EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.91264265
154TCF4_23295773_ChIP-Seq_U87_Human0.91212069
155CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90834413
156GATA3_21867929_ChIP-Seq_CD8_Mouse0.90170248
157STAT1_20625510_ChIP-Seq_HELA_Human0.89602186
158EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.89319079
159ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88709954
160SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.88506321
161RXR_22158963_ChIP-Seq_LIVER_Mouse0.86950160
162SMC1_22415368_ChIP-Seq_MEFs_Mouse0.86345024
163MYC_27129775_Chip-Seq_CORNEA_Mouse0.85863286
164NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.85414296
165CTCF_27219007_Chip-Seq_ERYTHROID_Human0.84492857
166SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.84278882
167MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.83002665
168CLOCK_20551151_ChIP-Seq_293T_Human0.82686043
169PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.82180609
170SA1_22415368_ChIP-Seq_MEFs_Mouse0.81156061
171SOX11_22085726_ChIP-Seq_ESNs_Mouse0.80766563
172FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.79301888

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000751_myopathy5.51356582
2MP0003646_muscle_fatigue5.30627920
3MP0000749_muscle_degeneration4.74216009
4MP0004145_abnormal_muscle_electrophysio4.38199637
5MP0002837_dystrophic_cardiac_calcinosis4.23398940
6MP0004270_analgesia3.68843734
7MP0005451_abnormal_body_composition3.55603518
8MP0004036_abnormal_muscle_relaxation3.25538300
9MP0002106_abnormal_muscle_physiology3.16758228
10MP0000750_abnormal_muscle_regeneration2.91006558
11MP0004084_abnormal_cardiac_muscle2.86272155
12MP0005369_muscle_phenotype2.83733672
13MP0004215_abnormal_myocardial_fiber2.76846554
14MP0005503_abnormal_tendon_morphology2.75920958
15MP0000759_abnormal_skeletal_muscle2.71629742
16MP0005620_abnormal_muscle_contractility2.66732227
17MP0004087_abnormal_muscle_fiber2.64137921
18MP0002254_reproductive_system_inflammat2.41296969
19MP0000747_muscle_weakness2.39848306
20MP0002108_abnormal_muscle_morphology2.28216553
21MP0005330_cardiomyopathy2.20530438
22MP0002269_muscular_atrophy2.08813620
23MP0002972_abnormal_cardiac_muscle2.00287845
24MP0000733_abnormal_muscle_development1.95086943
25MP0001346_abnormal_lacrimal_gland1.85363503
26MP0005171_absent_coat_pigmentation1.79543176
27MP0004233_abnormal_muscle_weight1.74114019
28MP0002332_abnormal_exercise_endurance1.72895213
29MP0005275_abnormal_skin_tensile1.62556198
30MP0004130_abnormal_muscle_cell1.61784214
31MP0004484_altered_response_of1.56219241
32MP0004510_myositis1.52120657
33MP0003828_pulmonary_edema1.45826981
34MP0006138_congestive_heart_failure1.44047529
35MP0010030_abnormal_orbit_morphology1.37668245
36MP0003941_abnormal_skin_development1.35514840
37MP0001544_abnormal_cardiovascular_syste1.33878220
38MP0005385_cardiovascular_system_phenoty1.33878220
39MP0002876_abnormal_thyroid_physiology1.32070469
40MP0001661_extended_life_span1.29447314
41MP0003137_abnormal_impulse_conducting1.29127850
42MP0000372_irregular_coat_pigmentation1.29008693
43MP0008775_abnormal_heart_ventricle1.27093945
44MP0005266_abnormal_metabolism1.24461036
45MP0009250_abnormal_appendicular_skeleto1.22269990
46MP0010630_abnormal_cardiac_muscle1.21744953
47MP0010368_abnormal_lymphatic_system1.21113843
48MP0004085_abnormal_heartbeat1.15583102
49MP0004272_abnormal_basement_membrane1.15314099
50MP0001879_abnormal_lymphatic_vessel1.11049061
51MP0002249_abnormal_larynx_morphology0.99218440
52MP0005645_abnormal_hypothalamus_physiol0.98588622
53MP0002638_abnormal_pupillary_reflex0.97069911
54MP0000003_abnormal_adipose_tissue0.95949262
55MP0002735_abnormal_chemical_nociception0.90620295
56MP0000762_abnormal_tongue_morphology0.89943283
57MP0005623_abnormal_meninges_morphology0.89920394
58MP0005248_abnormal_Harderian_gland0.88477538
59MP0003385_abnormal_body_wall0.88418788
60MP0002277_abnormal_respiratory_mucosa0.88252777
61MP0002127_abnormal_cardiovascular_syste0.87490182
62MP0002163_abnormal_gland_morphology0.84859450
63MP0000566_synostosis0.84500416
64MP0000678_abnormal_parathyroid_gland0.82731272
65MP0003279_aneurysm0.81596377
66MP0002234_abnormal_pharynx_morphology0.81582714
67MP0008438_abnormal_cutaneous_collagen0.80912158
68MP0001188_hyperpigmentation0.78196118
69MP0005508_abnormal_skeleton_morphology0.77165691
70MP0002734_abnormal_mechanical_nocicepti0.76636393
71MP0009697_abnormal_copulation0.75666293
72MP0005646_abnormal_pituitary_gland0.73061580
73MP0004185_abnormal_adipocyte_glucose0.72221050
74MP0000266_abnormal_heart_morphology0.70779808
75MP0002822_catalepsy0.69985409
76MP0005375_adipose_tissue_phenotype0.68544462
77MP0001529_abnormal_vocalization0.66802555
78MP0009780_abnormal_chondrocyte_physiolo0.65132944
79MP0002971_abnormal_brown_adipose0.65096957
80MP0000049_abnormal_middle_ear0.63481136
81MP0002114_abnormal_axial_skeleton0.62132091
82MP0003950_abnormal_plasma_membrane0.62075558
83MP0003879_abnormal_hair_cell0.59531543
84MP0010386_abnormal_urinary_bladder0.58772100
85MP0002877_abnormal_melanocyte_morpholog0.58546450
86MP0001270_distended_abdomen0.57236663
87MP0003122_maternal_imprinting0.56458664
88MP0000013_abnormal_adipose_tissue0.56425973
89MP0002938_white_spotting0.56231947
90MP0001501_abnormal_sleep_pattern0.53232147
91MP0003221_abnormal_cardiomyocyte_apopto0.52202774
92MP0003755_abnormal_palate_morphology0.52100892
93MP0000767_abnormal_smooth_muscle0.51383392
94MP0000343_altered_response_to0.51165278
95MP0001348_abnormal_lacrimal_gland0.50722179
96MP0005666_abnormal_adipose_tissue0.50686536
97MP0008007_abnormal_cellular_replicative0.50562927
98MP0005670_abnormal_white_adipose0.50075161
99MP0004142_abnormal_muscle_tone0.48120627
100MP0002109_abnormal_limb_morphology0.48020113
101MP0006276_abnormal_autonomic_nervous0.47963520
102MP0003567_abnormal_fetal_cardiomyocyte0.47847882
103MP0002128_abnormal_blood_circulation0.47839594
104MP0004134_abnormal_chest_morphology0.47791329
105MP0001299_abnormal_eye_distance/0.46868018
106MP0005423_abnormal_somatic_nervous0.45542967
107MP0000681_abnormal_thyroid_gland0.45475289
108MP0001542_abnormal_bone_strength0.43293900
109MP0002184_abnormal_innervation0.43225464
110MP0000579_abnormal_nail_morphology0.43074743
111MP0006036_abnormal_mitochondrial_physio0.42512041
112MP0006035_abnormal_mitochondrial_morpho0.42037753
113MP0004147_increased_porphyrin_level0.40703876
114MP0000163_abnormal_cartilage_morphology0.40153151
115MP0001440_abnormal_grooming_behavior0.39565187
116MP0001984_abnormal_olfaction0.39183052
117MP0002896_abnormal_bone_mineralization0.38625142
118MP0008569_lethality_at_weaning0.38488436
119MP0003948_abnormal_gas_homeostasis0.38076518
120MP0005083_abnormal_biliary_tract0.37883136
121MP0003045_fibrosis0.34944621
122MP0002078_abnormal_glucose_homeostasis0.32698803
123MP0001943_abnormal_respiration0.32677029
124MP0002932_abnormal_joint_morphology0.32398469
125MP0004858_abnormal_nervous_system0.32108875
126MP0005376_homeostasis/metabolism_phenot0.31635165
127MP0000534_abnormal_ureter_morphology0.31042376
128MP0002066_abnormal_motor_capabilities/c0.28857369
129MP0004043_abnormal_pH_regulation0.28280456
130MP0008789_abnormal_olfactory_epithelium0.27741036
131MP0005452_abnormal_adipose_tissue0.27251619
132MP0009672_abnormal_birth_weight0.26905208
133MP0005332_abnormal_amino_acid0.26002786

Predicted human phenotypes

RankGene SetZ-score
1Muscle fiber inclusion bodies (HP:0100299)7.12726383
2Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)7.04301458
3Nemaline bodies (HP:0003798)6.57226308
4Type 1 muscle fiber predominance (HP:0003803)6.31684600
5Muscle fiber splitting (HP:0003555)5.82069883
6Muscle hypertrophy of the lower extremities (HP:0008968)5.63486064
7Exercise-induced myalgia (HP:0003738)5.54417397
8Distal arthrogryposis (HP:0005684)5.51616329
9Calf muscle hypertrophy (HP:0008981)5.50486315
10Exercise-induced muscle cramps (HP:0003710)5.25251455
11Hepatoblastoma (HP:0002884)5.00091145
12Neonatal hypoglycemia (HP:0001998)4.91275211
13Abnormality of the calf musculature (HP:0001430)4.87578290
14Round ear (HP:0100830)4.63121030
15Fetal akinesia sequence (HP:0001989)4.40867138
16Neoplasm of the adrenal cortex (HP:0100641)4.39810296
17Ulnar deviation of the wrist (HP:0003049)4.34242572
18EMG: myopathic abnormalities (HP:0003458)4.31460571
19Distal lower limb muscle weakness (HP:0009053)4.11847793
20Hyporeflexia of lower limbs (HP:0002600)4.01147665
21Myopathic facies (HP:0002058)4.00277878
22Abnormal pancreas size (HP:0012094)3.95950925
23Increased connective tissue (HP:0009025)3.91841707
24Long foot (HP:0001833)3.80288988
25Difficulty running (HP:0009046)3.78675277
26Malignant hyperthermia (HP:0002047)3.69433058
27Sudden death (HP:0001699)3.66194840
28Fatigable weakness (HP:0003473)3.59685179
29Abnormality of the neuromuscular junction (HP:0003398)3.59685179
30Diastasis recti (HP:0001540)3.51940133
31Aplasia of the musculature (HP:0100854)3.32616718
32Calcaneovalgus deformity (HP:0001848)3.29261642
33Overgrowth (HP:0001548)3.28556751
34Subaortic stenosis (HP:0001682)3.25727524
35Abnormality of the left ventricular outflow tract (HP:0011103)3.25727524
36Absent phalangeal crease (HP:0006109)3.24115702
37Weak cry (HP:0001612)3.18024220
38Deformed tarsal bones (HP:0008119)3.13343884
39Myotonia (HP:0002486)3.10662423
40Mildly elevated creatine phosphokinase (HP:0008180)3.02681131
41Abnormality of skeletal muscle fiber size (HP:0012084)3.00996845
42Popliteal pterygium (HP:0009756)3.00531720
43Type 2 muscle fiber atrophy (HP:0003554)3.00309210
44Neck muscle weakness (HP:0000467)2.84773683
45Hip contracture (HP:0003273)2.82561775
46Bulbar palsy (HP:0001283)2.79830227
47Advanced eruption of teeth (HP:0006288)2.78452680
48Distal lower limb amyotrophy (HP:0008944)2.78259604
49Difficulty climbing stairs (HP:0003551)2.73880173
50Abnormal finger flexion creases (HP:0006143)2.73740051
51Ventricular tachycardia (HP:0004756)2.67153028
52Neoplasm of the adrenal gland (HP:0100631)2.66750755
53Gowers sign (HP:0003391)2.64695756
54Increased variability in muscle fiber diameter (HP:0003557)2.57593724
55Myoglobinuria (HP:0002913)2.56619680
56Facial diplegia (HP:0001349)2.56394244
57Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.56087769
58Atrial fibrillation (HP:0005110)2.52349796
59Enlarged kidneys (HP:0000105)2.49527174
60Hypoplastic ischia (HP:0003175)2.47096038
61Nonprogressive disorder (HP:0003680)2.46477554
62Amniotic constriction ring (HP:0009775)2.45958206
63Abnormality of placental membranes (HP:0011409)2.45958206
64Muscle fiber atrophy (HP:0100295)2.43668486
65Muscle stiffness (HP:0003552)2.42430092
66Generalized muscle weakness (HP:0003324)2.42414135
67Slender build (HP:0001533)2.33251374
68Areflexia of lower limbs (HP:0002522)2.32030062
69Prolonged QT interval (HP:0001657)2.31312188
70Limb-girdle muscle atrophy (HP:0003797)2.28992584
71Primary atrial arrhythmia (HP:0001692)2.28649396
72Scapular winging (HP:0003691)2.25869097
73Abnormal glucose tolerance (HP:0001952)2.25275338
74Lower limb amyotrophy (HP:0007210)2.24382308
75Progressive muscle weakness (HP:0003323)2.23629382
76Proximal amyotrophy (HP:0007126)2.23122106
77Lipoatrophy (HP:0100578)2.22051978
78Limited hip movement (HP:0008800)2.20675676
79Bundle branch block (HP:0011710)2.19764637
80Supraventricular tachycardia (HP:0004755)2.14730821
81Spinal rigidity (HP:0003306)2.14036362
82Supraventricular arrhythmia (HP:0005115)2.13195430
83Right ventricular cardiomyopathy (HP:0011663)2.12131750
84Easy fatigability (HP:0003388)2.10500816
85Germ cell neoplasia (HP:0100728)2.10424860
86Long clavicles (HP:0000890)2.09172473
87Abnormality of the ischium (HP:0003174)2.08478642
88Asymmetric septal hypertrophy (HP:0001670)2.07225712
89Rimmed vacuoles (HP:0003805)2.06988128
90Metatarsus adductus (HP:0001840)2.06563550
91Ragged-red muscle fibers (HP:0003200)2.02986220
92Rhabdomyolysis (HP:0003201)2.01561988
93High anterior hairline (HP:0009890)1.99554486
94Breech presentation (HP:0001623)1.96729969
95Frequent falls (HP:0002359)1.95464035
96Exercise intolerance (HP:0003546)1.91989445
97Waddling gait (HP:0002515)1.89077640
98Deep philtrum (HP:0002002)1.86982527
99Hyperkalemia (HP:0002153)1.84840060
100Abnormality of the calcaneus (HP:0008364)1.83101377
101Dilated cardiomyopathy (HP:0001644)1.82521143
102Respiratory insufficiency due to muscle weakness (HP:0002747)1.81477240
103Hypoplastic heart (HP:0001961)1.80822821
104Ulnar deviation of finger (HP:0009465)1.80452268
105Shoulder girdle muscle weakness (HP:0003547)1.79796558
106Muscular dystrophy (HP:0003560)1.77311747
107Abnormality of the shoulder girdle musculature (HP:0001435)1.77310798
108Abnormality of the foot musculature (HP:0001436)1.77245415
109EMG: neuropathic changes (HP:0003445)1.76139103
110Abnormality of the musculature of the pelvis (HP:0001469)1.75494215
111Abnormality of the hip-girdle musculature (HP:0001445)1.75494215
112Limb-girdle muscle weakness (HP:0003325)1.75243482
113Thin ribs (HP:0000883)1.74573139
114Centrally nucleated skeletal muscle fibers (HP:0003687)1.73750934
115Palpitations (HP:0001962)1.72863722
116Adducted thumb (HP:0001181)1.69473746
117Increased intramyocellular lipid droplets (HP:0012240)1.67148358
118Pelvic girdle muscle weakness (HP:0003749)1.64712705
119Foot dorsiflexor weakness (HP:0009027)1.63529682
120Heart block (HP:0012722)1.52415163
121Trismus (HP:0000211)1.51771786
122Rocker bottom foot (HP:0001838)1.51148677
123Paralysis (HP:0003470)1.50865996
124Ulnar deviation of the hand or of fingers of the hand (HP:0001193)1.50705741
125Increased muscle lipid content (HP:0009058)1.50287451
126Infantile muscular hypotonia (HP:0008947)1.49202020
127Abnormal atrioventricular conduction (HP:0005150)1.47935998

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN6.01208699
2TTN4.02182979
3PRKG23.39949845
4MUSK3.35765718
5PHKG23.33362050
6PHKG13.33362050
7STK163.22690750
8SIK32.74117678
9CASK2.55517505
10AKT32.49848158
11NME12.48928853
12PIK3CG2.37534064
13MKNK22.15098062
14RIPK12.03472962
15MYLK1.99955826
16TIE11.84790348
17MAP3K121.73550590
18PINK11.73080087
19PIK3CA1.72638358
20ZAK1.68450740
21VRK21.48967711
22BCKDK1.46941306
23CAMK2G1.43295343
24CAMK2D1.41114542
25EPHA31.39038277
26LIMK11.37081688
27SIK11.34078731
28CAMK2B1.24512399
29TAOK21.24035177
30MARK11.23391434
31MAPK121.23076623
32DMPK1.22222037
33GRK71.20234536
34DYRK1B1.18604952
35LMTK21.17624549
36CDK81.10566230
37MARK31.09808146
38ERBB31.09404006
39MAP3K141.06278508
40SGK20.98274419
41TRIB30.98063890
42SIK20.93906774
43PDK20.88438773
44MOS0.88317362
45EEF2K0.87245192
46INSRR0.86972355
47CAMK2A0.83841456
48EPHB20.81551577
49MKNK10.78114485
50PRPF4B0.77780769
51MAP3K70.77729111
52TGFBR20.74600096
53MAP2K10.74376356
54PTK2B0.72359255
55ROCK10.70588392
56NEK90.67988086
57SGK30.67598660
58CAMK40.65820297
59PDK30.65210134
60PDK40.65210134
61PRKG10.62858900
62PLK20.62648668
63MAPK130.60586831
64NLK0.60380814
65MAP2K60.59907262
66SGK10.58844825
67NEK10.58617995
68DYRK30.58140418
69PRKAA20.56969802
70MAPK70.56375387
71TNIK0.55907217
72EPHB10.55342967
73PRKCE0.54672374
74TRPM70.54336344
75NTRK30.54059203
76ICK0.53576828
77FER0.53110684
78MAPK110.52879815
79EPHA40.51890021
80STK38L0.51391420
81BMPR20.51068231
82DDR20.50076240
83STK240.47713533
84MAP4K20.47119414
85MAP2K30.46566321
86CAMK10.46323836
87MAP3K30.42784926
88LATS20.42765655
89MAPK40.40175411
90PRKACA0.40155992
91AKT20.39297705
92SGK2230.36096751
93SGK4940.36096751
94DYRK1A0.34613572
95ROCK20.34219682
96VRK10.34067481
97PKN10.33256519
98YES10.33138195
99PRKCI0.32960172
100PRKAA10.32837074
101BCR0.31471099
102NEK20.31105026
103ADRBK10.31004687
104WNK10.30891580
105BMPR1B0.30817340
106PRKACB0.29960673
107TBK10.29519520
108CHUK0.29432135
109FLT30.29388767
110MAPKAPK30.28824331
111MAP2K40.27478877
112MAP3K100.25813192
113FGFR40.25222193
114FGFR30.25067659
115CCNB10.24811564
116DAPK30.23622640
117PRKACG0.23373172
118CDC42BPA0.23164098
119ARAF0.22982560
120MARK20.22959755
121JAK30.22867559
122HIPK20.22688815
123LATS10.22488093
124TESK10.22198847
125RPS6KA30.21623295
126PAK60.20381579
127MAPK150.19433201
128RPS6KB10.19368409
129PRKD10.17935164
130RPS6KL10.17469826
131RPS6KC10.17469826
132RPS6KA10.17466085
133RPS6KB20.17261237
134CDK190.14467917
135MAPK100.13971502
136ABL20.13195733
137KSR20.12650774
138RPS6KA60.12231088
139MTOR0.10512292
140CSNK1D0.09442125
141MAPK80.08909288
142MAPKAPK50.08628380
143PAK10.07990723
144CSNK1A10.07772759
145ILK0.07438480
146MAPKAPK20.06865278
147PDPK10.06617243
148MAPK90.06518635
149PDGFRA0.06206359
150MAP3K60.05666601

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.83080863
2Dilated cardiomyopathy_Homo sapiens_hsa054143.49931101
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.27378426
4Cardiac muscle contraction_Homo sapiens_hsa042602.90683548
5African trypanosomiasis_Homo sapiens_hsa051432.45842154
6Carbon metabolism_Homo sapiens_hsa012002.44391783
7Arginine and proline metabolism_Homo sapiens_hsa003302.21991239
8Pentose phosphate pathway_Homo sapiens_hsa000302.12670362
9Pyruvate metabolism_Homo sapiens_hsa006202.10250827
10Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.00277916
11Renin secretion_Homo sapiens_hsa049241.95738448
12Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.91782969
13Calcium signaling pathway_Homo sapiens_hsa040201.91131718
14Oxytocin signaling pathway_Homo sapiens_hsa049211.88839212
15Biosynthesis of amino acids_Homo sapiens_hsa012301.82977259
16Gastric acid secretion_Homo sapiens_hsa049711.77617658
17Fructose and mannose metabolism_Homo sapiens_hsa000511.73775931
18Insulin secretion_Homo sapiens_hsa049111.71536123
19Propanoate metabolism_Homo sapiens_hsa006401.69024742
20Circadian entrainment_Homo sapiens_hsa047131.63464998
21Circadian rhythm_Homo sapiens_hsa047101.62850668
22Fatty acid degradation_Homo sapiens_hsa000711.56978516
23Glucagon signaling pathway_Homo sapiens_hsa049221.56648725
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.52346148
25Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.49820482
26Arginine biosynthesis_Homo sapiens_hsa002201.49031254
27Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.48536139
28cGMP-PKG signaling pathway_Homo sapiens_hsa040221.44649973
29Serotonergic synapse_Homo sapiens_hsa047261.42937808
30Salivary secretion_Homo sapiens_hsa049701.40958899
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.40232748
32Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.38218989
33Viral myocarditis_Homo sapiens_hsa054161.37455302
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.36599987
35Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.36196688
36Vascular smooth muscle contraction_Homo sapiens_hsa042701.34356657
37Alzheimers disease_Homo sapiens_hsa050101.33675347
38Long-term potentiation_Homo sapiens_hsa047201.32675635
39Long-term depression_Homo sapiens_hsa047301.30722145
40Aldosterone synthesis and secretion_Homo sapiens_hsa049251.29665446
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.29344746
42GnRH signaling pathway_Homo sapiens_hsa049121.28181337
43Oxidative phosphorylation_Homo sapiens_hsa001901.26597383
44Fatty acid metabolism_Homo sapiens_hsa012121.26173561
45Nitrogen metabolism_Homo sapiens_hsa009101.24981311
46Cholinergic synapse_Homo sapiens_hsa047251.24177294
47Collecting duct acid secretion_Homo sapiens_hsa049661.22710064
48Nicotine addiction_Homo sapiens_hsa050331.21955279
49Amoebiasis_Homo sapiens_hsa051461.21227675
50Focal adhesion_Homo sapiens_hsa045101.19012012
51ECM-receptor interaction_Homo sapiens_hsa045121.18764170
52Fatty acid elongation_Homo sapiens_hsa000621.15547300
53Autoimmune thyroid disease_Homo sapiens_hsa053201.12447535
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.12024752
55Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.11963987
56AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.05892120
57Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.02427344
58Taste transduction_Homo sapiens_hsa047421.01422392
59Melanogenesis_Homo sapiens_hsa049160.95637705
60Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.94979355
61Parkinsons disease_Homo sapiens_hsa050120.94798209
62Sulfur relay system_Homo sapiens_hsa041220.94190674
63Morphine addiction_Homo sapiens_hsa050320.93561296
64Olfactory transduction_Homo sapiens_hsa047400.91310975
65AMPK signaling pathway_Homo sapiens_hsa041520.90072126
66Peroxisome_Homo sapiens_hsa041460.89572222
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88256808
68Tight junction_Homo sapiens_hsa045300.88026219
69Glutamatergic synapse_Homo sapiens_hsa047240.86514511
70Lysine degradation_Homo sapiens_hsa003100.86146397
71Rheumatoid arthritis_Homo sapiens_hsa053230.86015577
72Insulin resistance_Homo sapiens_hsa049310.85778738
73Insulin signaling pathway_Homo sapiens_hsa049100.82631685
74Inositol phosphate metabolism_Homo sapiens_hsa005620.81808054
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81155974
76Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79908665
77Thyroid hormone signaling pathway_Homo sapiens_hsa049190.79587887
78Adherens junction_Homo sapiens_hsa045200.77857758
79Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77271816
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.77018189
81Gap junction_Homo sapiens_hsa045400.75270488
82cAMP signaling pathway_Homo sapiens_hsa040240.74081504
83Thyroid hormone synthesis_Homo sapiens_hsa049180.73807435
84SNARE interactions in vesicular transport_Homo sapiens_hsa041300.73075998
85Huntingtons disease_Homo sapiens_hsa050160.72552069
86Dopaminergic synapse_Homo sapiens_hsa047280.71455590
87Butanoate metabolism_Homo sapiens_hsa006500.69775437
88Synaptic vesicle cycle_Homo sapiens_hsa047210.68351128
89MAPK signaling pathway_Homo sapiens_hsa040100.68018900
90Galactose metabolism_Homo sapiens_hsa000520.68014276
91Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66604165
92Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.66007199
93Starch and sucrose metabolism_Homo sapiens_hsa005000.65307071
94Protein digestion and absorption_Homo sapiens_hsa049740.64689441
95Allograft rejection_Homo sapiens_hsa053300.64684593
96Pancreatic secretion_Homo sapiens_hsa049720.64499184
97beta-Alanine metabolism_Homo sapiens_hsa004100.62232069
98Purine metabolism_Homo sapiens_hsa002300.61900077
99Phenylalanine metabolism_Homo sapiens_hsa003600.61893752
100Wnt signaling pathway_Homo sapiens_hsa043100.61240809
101GABAergic synapse_Homo sapiens_hsa047270.58408858
102Intestinal immune network for IgA production_Homo sapiens_hsa046720.58349325
103Amphetamine addiction_Homo sapiens_hsa050310.57853657
104Platelet activation_Homo sapiens_hsa046110.57739259
105Melanoma_Homo sapiens_hsa052180.57332718
106FoxO signaling pathway_Homo sapiens_hsa040680.57093782
107Proteoglycans in cancer_Homo sapiens_hsa052050.57069540
108Osteoclast differentiation_Homo sapiens_hsa043800.56551571
109Adipocytokine signaling pathway_Homo sapiens_hsa049200.56404573
110Axon guidance_Homo sapiens_hsa043600.55352359
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55067523
112Rap1 signaling pathway_Homo sapiens_hsa040150.54514173
113Malaria_Homo sapiens_hsa051440.54440764
114Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54307520
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.53260806
116HIF-1 signaling pathway_Homo sapiens_hsa040660.51145661
1172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.50760469
118Estrogen signaling pathway_Homo sapiens_hsa049150.49023076
119Type II diabetes mellitus_Homo sapiens_hsa049300.49001866
120Vibrio cholerae infection_Homo sapiens_hsa051100.47769035
121Phagosome_Homo sapiens_hsa041450.46485672
122Chemokine signaling pathway_Homo sapiens_hsa040620.45841912
123TNF signaling pathway_Homo sapiens_hsa046680.44798211
124Toll-like receptor signaling pathway_Homo sapiens_hsa046200.44488542
125Cysteine and methionine metabolism_Homo sapiens_hsa002700.44143557
126Legionellosis_Homo sapiens_hsa051340.43455912
127PPAR signaling pathway_Homo sapiens_hsa033200.41671277
128Basal cell carcinoma_Homo sapiens_hsa052170.40242262
129Tryptophan metabolism_Homo sapiens_hsa003800.40203609
130Folate biosynthesis_Homo sapiens_hsa007900.39974972
131Asthma_Homo sapiens_hsa053100.39483363
132Ribosome_Homo sapiens_hsa030100.38277404
133Leukocyte transendothelial migration_Homo sapiens_hsa046700.37604155
134Type I diabetes mellitus_Homo sapiens_hsa049400.37231987
135Base excision repair_Homo sapiens_hsa034100.36524289
136Nucleotide excision repair_Homo sapiens_hsa034200.36232255
137Metabolic pathways_Homo sapiens_hsa011000.36187836
138Glutathione metabolism_Homo sapiens_hsa004800.35079411
139Histidine metabolism_Homo sapiens_hsa003400.34548996
140Oocyte meiosis_Homo sapiens_hsa041140.32107573
141Phototransduction_Homo sapiens_hsa047440.31898975
142Longevity regulating pathway - mammal_Homo sapiens_hsa042110.29912694
143Regulation of autophagy_Homo sapiens_hsa041400.25618283
144Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.23586899
145RNA polymerase_Homo sapiens_hsa030200.23294655
146Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.23226122
147Tyrosine metabolism_Homo sapiens_hsa003500.21524183
148Ovarian steroidogenesis_Homo sapiens_hsa049130.19919089
149ABC transporters_Homo sapiens_hsa020100.17923105
150Central carbon metabolism in cancer_Homo sapiens_hsa052300.15660888
151Bile secretion_Homo sapiens_hsa049760.14671943
152Cyanoamino acid metabolism_Homo sapiens_hsa004600.14251950
153Hedgehog signaling pathway_Homo sapiens_hsa043400.09037866

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