Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.19427964 |
2 | synaptic vesicle maturation (GO:0016188) | 6.12304096 |
3 | locomotory exploration behavior (GO:0035641) | 6.07677463 |
4 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.65994817 |
5 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.51252783 |
6 | vocalization behavior (GO:0071625) | 5.49309124 |
7 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.24701103 |
8 | layer formation in cerebral cortex (GO:0021819) | 5.24321387 |
9 | synaptic vesicle exocytosis (GO:0016079) | 5.09246612 |
10 | glutamate secretion (GO:0014047) | 5.06587991 |
11 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.96428698 |
12 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.95528737 |
13 | protein localization to synapse (GO:0035418) | 4.90205564 |
14 | exploration behavior (GO:0035640) | 4.88309087 |
15 | neuron cell-cell adhesion (GO:0007158) | 4.87094371 |
16 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.83912848 |
17 | dendritic spine morphogenesis (GO:0060997) | 4.73830835 |
18 | regulation of synapse structural plasticity (GO:0051823) | 4.66641613 |
19 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.45922761 |
20 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.42419771 |
21 | regulation of synaptic vesicle transport (GO:1902803) | 4.38109102 |
22 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.36417946 |
23 | neurotransmitter secretion (GO:0007269) | 4.33249915 |
24 | establishment of mitochondrion localization (GO:0051654) | 4.27108290 |
25 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.23120317 |
26 | proline transport (GO:0015824) | 4.18627579 |
27 | synaptic transmission, glutamatergic (GO:0035249) | 4.03621316 |
28 | gamma-aminobutyric acid transport (GO:0015812) | 4.02946719 |
29 | neuron recognition (GO:0008038) | 4.01716101 |
30 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.99032572 |
31 | glutamate receptor signaling pathway (GO:0007215) | 3.93485867 |
32 | axonal fasciculation (GO:0007413) | 3.85294628 |
33 | * dendrite morphogenesis (GO:0048813) | 3.81891452 |
34 | long-term memory (GO:0007616) | 3.76477689 |
35 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.76150661 |
36 | neuron-neuron synaptic transmission (GO:0007270) | 3.75350847 |
37 | positive regulation of membrane potential (GO:0045838) | 3.74490856 |
38 | positive regulation of synapse maturation (GO:0090129) | 3.74110403 |
39 | activation of protein kinase A activity (GO:0034199) | 3.73753719 |
40 | postsynaptic membrane organization (GO:0001941) | 3.73264452 |
41 | mechanosensory behavior (GO:0007638) | 3.69874510 |
42 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.66064740 |
43 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.64019506 |
44 | cell migration in hindbrain (GO:0021535) | 3.63013493 |
45 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.60902248 |
46 | neuronal action potential propagation (GO:0019227) | 3.60813142 |
47 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.59896529 |
48 | auditory behavior (GO:0031223) | 3.58312390 |
49 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.56897512 |
50 | neuromuscular process controlling balance (GO:0050885) | 3.54461644 |
51 | startle response (GO:0001964) | 3.52540025 |
52 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.50711001 |
53 | mitochondrion transport along microtubule (GO:0047497) | 3.50711001 |
54 | positive regulation of synapse assembly (GO:0051965) | 3.48389793 |
55 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.44748004 |
56 | neurotransmitter transport (GO:0006836) | 3.44395894 |
57 | cellular potassium ion homeostasis (GO:0030007) | 3.43753250 |
58 | response to auditory stimulus (GO:0010996) | 3.43439309 |
59 | regulation of postsynaptic membrane potential (GO:0060078) | 3.43226603 |
60 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.42340832 |
61 | sodium ion export (GO:0071436) | 3.36925569 |
62 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.36679802 |
63 | transmission of nerve impulse (GO:0019226) | 3.36031267 |
64 | regulation of synaptic plasticity (GO:0048167) | 3.34827479 |
65 | synaptic vesicle endocytosis (GO:0048488) | 3.33081989 |
66 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.28099844 |
67 | regulation of neurotransmitter secretion (GO:0046928) | 3.28009863 |
68 | vesicle transport along microtubule (GO:0047496) | 3.26468120 |
69 | central nervous system neuron axonogenesis (GO:0021955) | 3.26159463 |
70 | prepulse inhibition (GO:0060134) | 3.24170156 |
71 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.23086220 |
72 | innervation (GO:0060384) | 3.22737552 |
73 | organelle transport along microtubule (GO:0072384) | 3.22177158 |
74 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.21705445 |
75 | synapse assembly (GO:0007416) | 3.20506972 |
76 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.20046100 |
77 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.19474240 |
78 | presynaptic membrane assembly (GO:0097105) | 3.18333252 |
79 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.17356478 |
80 | dendritic spine organization (GO:0097061) | 3.17243882 |
81 | cell communication by electrical coupling (GO:0010644) | 3.16209555 |
82 | clathrin coat assembly (GO:0048268) | 3.15837039 |
83 | establishment of nucleus localization (GO:0040023) | 3.15716978 |
84 | adult walking behavior (GO:0007628) | 3.15383740 |
85 | regulation of neurotransmitter levels (GO:0001505) | 3.15032519 |
86 | nucleobase catabolic process (GO:0046113) | 3.15019665 |
87 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.13584533 |
88 | positive regulation of dendritic spine development (GO:0060999) | 3.13510824 |
89 | membrane depolarization during action potential (GO:0086010) | 3.11959259 |
90 | regulation of ARF protein signal transduction (GO:0032012) | 3.10910727 |
91 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.09857511 |
92 | cerebellar granule cell differentiation (GO:0021707) | 3.09158743 |
93 | retinal ganglion cell axon guidance (GO:0031290) | 3.08553539 |
94 | regulation of dendritic spine development (GO:0060998) | 3.07996841 |
95 | negative regulation of dendrite development (GO:2000171) | 3.07032478 |
96 | long-term synaptic potentiation (GO:0060291) | 3.06426314 |
97 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.05996425 |
98 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.03906319 |
99 | glycine transport (GO:0015816) | 3.03580698 |
100 | regulation of vesicle fusion (GO:0031338) | 3.02466272 |
101 | neuromuscular synaptic transmission (GO:0007274) | 3.02329720 |
102 | social behavior (GO:0035176) | 3.01087509 |
103 | intraspecies interaction between organisms (GO:0051703) | 3.01087509 |
104 | regulation of neurotransmitter transport (GO:0051588) | 2.99098304 |
105 | neuronal ion channel clustering (GO:0045161) | 2.98484979 |
106 | learning (GO:0007612) | 2.97524595 |
107 | synapse organization (GO:0050808) | 2.97400808 |
108 | presynaptic membrane organization (GO:0097090) | 2.96419949 |
109 | cerebellar Purkinje cell layer development (GO:0021680) | 2.96063425 |
110 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.94399907 |
111 | axon cargo transport (GO:0008088) | 2.93716487 |
112 | regulation of synapse assembly (GO:0051963) | 2.93630741 |
113 | membrane hyperpolarization (GO:0060081) | 2.92400842 |
114 | behavioral fear response (GO:0001662) | 2.92351283 |
115 | behavioral defense response (GO:0002209) | 2.92351283 |
116 | positive regulation of neurotransmitter transport (GO:0051590) | 2.91414268 |
117 | membrane depolarization (GO:0051899) | 2.90246457 |
118 | axon extension (GO:0048675) | 2.88425571 |
119 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.85623118 |
120 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.84101437 |
121 | negative regulation of axonogenesis (GO:0050771) | 2.82060715 |
122 | spinal cord development (GO:0021510) | 2.80025040 |
123 | behavioral response to nicotine (GO:0035095) | 2.79313317 |
124 | limb bud formation (GO:0060174) | 2.78896054 |
125 | glycosphingolipid biosynthetic process (GO:0006688) | 2.78648393 |
126 | hippocampus development (GO:0021766) | 2.75662719 |
127 | negative regulation of axon extension (GO:0030517) | 2.73695347 |
128 | axon ensheathment in central nervous system (GO:0032291) | 2.73190538 |
129 | central nervous system myelination (GO:0022010) | 2.73190538 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.02963324 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.37971804 |
3 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.00441466 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.97738012 |
5 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.88435873 |
6 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.76989406 |
7 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.59687014 |
8 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.59687014 |
9 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.57492353 |
10 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.55224173 |
11 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.53323977 |
12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.52133132 |
13 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.45583354 |
14 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.44707579 |
15 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.43515546 |
16 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.42499168 |
17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.36436396 |
18 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.30830079 |
19 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.26946269 |
20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.26605061 |
21 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.24993118 |
22 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.24710683 |
23 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.24118325 |
24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.19804757 |
25 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.18893081 |
26 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.15926894 |
27 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.12359829 |
28 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.06462489 |
29 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.04911853 |
30 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.04485222 |
31 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.89675512 |
32 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.86225179 |
33 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.78157065 |
34 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.72265413 |
35 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.65930977 |
36 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.59601449 |
37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.56538396 |
38 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.55591830 |
39 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.52158546 |
40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.48450181 |
41 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.45405464 |
42 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.40582064 |
43 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.37374635 |
44 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.37262011 |
45 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.33905498 |
46 | * SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.31725866 |
47 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.31502015 |
48 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.28688060 |
49 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.27739544 |
50 | AR_19668381_ChIP-Seq_PC3_Human | 1.27420676 |
51 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.26809132 |
52 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.25991761 |
53 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.25721493 |
54 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.25211536 |
55 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.25102490 |
56 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.24669556 |
57 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.24378136 |
58 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.24257932 |
59 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.22953460 |
60 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.21743768 |
61 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.21704859 |
62 | AR_25329375_ChIP-Seq_VCAP_Human | 1.21613988 |
63 | * P300_19829295_ChIP-Seq_ESCs_Human | 1.21441902 |
64 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.21163320 |
65 | KDM2B_26808549_Chip-Seq_K562_Human | 1.21056612 |
66 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.18077529 |
67 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.16784802 |
68 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.16393270 |
69 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.15579865 |
70 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.14508227 |
71 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.13693512 |
72 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12854691 |
73 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.12441632 |
74 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.11973278 |
75 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.11844729 |
76 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.11744222 |
77 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.11226933 |
78 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.09752717 |
79 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.09573722 |
80 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.09216537 |
81 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.08519060 |
82 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.07077346 |
83 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.06901473 |
84 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.06457121 |
85 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.06411434 |
86 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.05695247 |
87 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.05160945 |
88 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.04733713 |
89 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.04529282 |
90 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.04173346 |
91 | VDR_22108803_ChIP-Seq_LS180_Human | 1.03818783 |
92 | * EWS_26573619_Chip-Seq_HEK293_Human | 1.03311469 |
93 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.03160267 |
94 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.98337684 |
95 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98217591 |
96 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.98102761 |
97 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.97471704 |
98 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.97193752 |
99 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.97118429 |
100 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.97051985 |
101 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.97051985 |
102 | JUN_21703547_ChIP-Seq_K562_Human | 0.96633289 |
103 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.96361202 |
104 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.95773598 |
105 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.94348514 |
106 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.94139158 |
107 | KDM2B_26808549_Chip-Seq_REH_Human | 0.93435640 |
108 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 0.93159000 |
109 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.92822849 |
110 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92822849 |
111 | TP53_16413492_ChIP-PET_HCT116_Human | 0.92065422 |
112 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.91113980 |
113 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.90999097 |
114 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89531016 |
115 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.89409161 |
116 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.87804582 |
117 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.87728418 |
118 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.87433123 |
119 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.86823009 |
120 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86025350 |
121 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.85272829 |
122 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.84451730 |
123 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.84167099 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 6.73953239 |
2 | MP0003880_abnormal_central_pattern | 4.45974918 |
3 | MP0003635_abnormal_synaptic_transmissio | 4.16731742 |
4 | MP0004270_analgesia | 4.09027334 |
5 | MP0002063_abnormal_learning/memory/cond | 3.42623152 |
6 | MP0005423_abnormal_somatic_nervous | 3.41661234 |
7 | MP0009745_abnormal_behavioral_response | 3.23068544 |
8 | MP0002064_seizures | 2.94331592 |
9 | MP0009046_muscle_twitch | 2.78777778 |
10 | MP0002734_abnormal_mechanical_nocicepti | 2.75089292 |
11 | MP0001968_abnormal_touch/_nociception | 2.73843514 |
12 | MP0002572_abnormal_emotion/affect_behav | 2.71287148 |
13 | MP0001486_abnormal_startle_reflex | 2.52338767 |
14 | MP0000778_abnormal_nervous_system | 2.38775113 |
15 | MP0009780_abnormal_chondrocyte_physiolo | 2.30360314 |
16 | MP0002272_abnormal_nervous_system | 2.24283349 |
17 | MP0002822_catalepsy | 2.18502058 |
18 | MP0001440_abnormal_grooming_behavior | 2.06524536 |
19 | MP0002735_abnormal_chemical_nociception | 2.05953852 |
20 | MP0002733_abnormal_thermal_nociception | 2.05334536 |
21 | MP0004811_abnormal_neuron_physiology | 2.01250916 |
22 | MP0002184_abnormal_innervation | 1.97774856 |
23 | MP0000569_abnormal_digit_pigmentation | 1.97287997 |
24 | MP0004858_abnormal_nervous_system | 1.95890186 |
25 | MP0002736_abnormal_nociception_after | 1.91958942 |
26 | MP0002909_abnormal_adrenal_gland | 1.90526902 |
27 | MP0003329_amyloid_beta_deposits | 1.89255071 |
28 | MP0001501_abnormal_sleep_pattern | 1.89009090 |
29 | MP0001970_abnormal_pain_threshold | 1.87893426 |
30 | MP0002557_abnormal_social/conspecific_i | 1.87262774 |
31 | MP0002067_abnormal_sensory_capabilities | 1.85195247 |
32 | MP0008569_lethality_at_weaning | 1.80246976 |
33 | MP0004924_abnormal_behavior | 1.79223784 |
34 | MP0005386_behavior/neurological_phenoty | 1.79223784 |
35 | MP0000955_abnormal_spinal_cord | 1.78584614 |
36 | MP0004885_abnormal_endolymph | 1.77105509 |
37 | MP0003121_genomic_imprinting | 1.74751431 |
38 | MP0005645_abnormal_hypothalamus_physiol | 1.59682183 |
39 | MP0005646_abnormal_pituitary_gland | 1.58766082 |
40 | MP0003787_abnormal_imprinting | 1.55907200 |
41 | MP0002882_abnormal_neuron_morphology | 1.54905481 |
42 | MP0006276_abnormal_autonomic_nervous | 1.52929760 |
43 | MP0001984_abnormal_olfaction | 1.46318620 |
44 | MP0002066_abnormal_motor_capabilities/c | 1.43276697 |
45 | MP0003879_abnormal_hair_cell | 1.40655651 |
46 | MP0002152_abnormal_brain_morphology | 1.30434718 |
47 | MP0003633_abnormal_nervous_system | 1.29483819 |
48 | MP0001502_abnormal_circadian_rhythm | 1.19818923 |
49 | MP0003122_maternal_imprinting | 1.15206252 |
50 | MP0002751_abnormal_autonomic_nervous | 1.13437730 |
51 | MP0003631_nervous_system_phenotype | 1.10023336 |
52 | MP0001529_abnormal_vocalization | 1.07325205 |
53 | MP0003283_abnormal_digestive_organ | 1.07043460 |
54 | MP0004133_heterotaxia | 1.05973715 |
55 | MP0002653_abnormal_ependyma_morphology | 1.05169767 |
56 | MP0008877_abnormal_DNA_methylation | 1.04818921 |
57 | MP0000631_abnormal_neuroendocrine_gland | 1.03754986 |
58 | MP0000566_synostosis | 1.02545302 |
59 | MP0004142_abnormal_muscle_tone | 1.01728632 |
60 | MP0008961_abnormal_basal_metabolism | 1.01140653 |
61 | MP0002102_abnormal_ear_morphology | 0.99662693 |
62 | MP0003634_abnormal_glial_cell | 0.97965947 |
63 | MP0001905_abnormal_dopamine_level | 0.97204411 |
64 | MP0001177_atelectasis | 0.97176492 |
65 | MP0008789_abnormal_olfactory_epithelium | 0.96064220 |
66 | MP0002069_abnormal_eating/drinking_beha | 0.95952579 |
67 | MP0005187_abnormal_penis_morphology | 0.95603085 |
68 | MP0000026_abnormal_inner_ear | 0.94066992 |
69 | MP0005551_abnormal_eye_electrophysiolog | 0.94054449 |
70 | MP0002229_neurodegeneration | 0.93497266 |
71 | MP0005253_abnormal_eye_physiology | 0.91151643 |
72 | MP0003938_abnormal_ear_development | 0.90844876 |
73 | MP0005499_abnormal_olfactory_system | 0.89403608 |
74 | MP0005394_taste/olfaction_phenotype | 0.89403608 |
75 | MP0001188_hyperpigmentation | 0.88284223 |
76 | MP0003123_paternal_imprinting | 0.87003193 |
77 | MP0006292_abnormal_olfactory_placode | 0.86606552 |
78 | MP0004742_abnormal_vestibular_system | 0.85383325 |
79 | MP0003861_abnormal_nervous_system | 0.84667693 |
80 | MP0003690_abnormal_glial_cell | 0.84489237 |
81 | MP0003632_abnormal_nervous_system | 0.83235049 |
82 | MP0000751_myopathy | 0.81857254 |
83 | MP0003119_abnormal_digestive_system | 0.81775167 |
84 | MP0002752_abnormal_somatic_nervous | 0.80647286 |
85 | MP0004085_abnormal_heartbeat | 0.80543390 |
86 | MP0001299_abnormal_eye_distance/ | 0.80421624 |
87 | MP0000604_amyloidosis | 0.78615527 |
88 | MP0000013_abnormal_adipose_tissue | 0.77325335 |
89 | MP0005248_abnormal_Harderian_gland | 0.76854561 |
90 | MP0000049_abnormal_middle_ear | 0.76015395 |
91 | MP0003137_abnormal_impulse_conducting | 0.75381666 |
92 | MP0001963_abnormal_hearing_physiology | 0.72383937 |
93 | MP0008872_abnormal_physiological_respon | 0.72330351 |
94 | MP0002081_perinatal_lethality | 0.71975918 |
95 | MP0002090_abnormal_vision | 0.71888671 |
96 | MP0004145_abnormal_muscle_electrophysio | 0.70840754 |
97 | MP0010234_abnormal_vibrissa_follicle | 0.69931219 |
98 | MP0010386_abnormal_urinary_bladder | 0.69534813 |
99 | MP0002638_abnormal_pupillary_reflex | 0.68462997 |
100 | MP0003890_abnormal_embryonic-extraembry | 0.68128123 |
101 | MP0000920_abnormal_myelination | 0.68032159 |
102 | MP0005535_abnormal_body_temperature | 0.67864362 |
103 | MP0001348_abnormal_lacrimal_gland | 0.67680791 |
104 | MP0008874_decreased_physiological_sensi | 0.67416813 |
105 | MP0005195_abnormal_posterior_eye | 0.66154110 |
106 | MP0003075_altered_response_to | 0.65047023 |
107 | MP0003172_abnormal_lysosome_physiology | 0.64439399 |
108 | MP0001986_abnormal_taste_sensitivity | 0.64374370 |
109 | MP0004233_abnormal_muscle_weight | 0.62748518 |
110 | MP0003385_abnormal_body_wall | 0.62505012 |
111 | MP0006072_abnormal_retinal_apoptosis | 0.61990410 |
112 | MP0002233_abnormal_nose_morphology | 0.61594952 |
113 | MP0010769_abnormal_survival | 0.60904745 |
114 | MP0001943_abnormal_respiration | 0.59477943 |
115 | MP0010770_preweaning_lethality | 0.59367486 |
116 | MP0002082_postnatal_lethality | 0.59367486 |
117 | MP0002234_abnormal_pharynx_morphology | 0.58456185 |
118 | MP0005623_abnormal_meninges_morphology | 0.57955066 |
119 | MP0004215_abnormal_myocardial_fiber | 0.57050426 |
120 | MP0010768_mortality/aging | 0.56659654 |
121 | MP0001485_abnormal_pinna_reflex | 0.55416330 |
122 | MP0004130_abnormal_muscle_cell | 0.54665639 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Myokymia (HP:0002411) | 6.18285496 |
2 | Focal motor seizures (HP:0011153) | 6.14214601 |
3 | Focal seizures (HP:0007359) | 5.06849097 |
4 | Visual hallucinations (HP:0002367) | 4.85578483 |
5 | Epileptic encephalopathy (HP:0200134) | 4.21010901 |
6 | Supranuclear gaze palsy (HP:0000605) | 3.97394361 |
7 | Progressive cerebellar ataxia (HP:0002073) | 3.89995177 |
8 | Papilledema (HP:0001085) | 3.86311995 |
9 | Ankle clonus (HP:0011448) | 3.85217437 |
10 | Mutism (HP:0002300) | 3.83489079 |
11 | Action tremor (HP:0002345) | 3.59414119 |
12 | Broad-based gait (HP:0002136) | 3.55007854 |
13 | Absence seizures (HP:0002121) | 3.47078006 |
14 | Febrile seizures (HP:0002373) | 3.43974337 |
15 | Atonic seizures (HP:0010819) | 3.38989147 |
16 | Poor eye contact (HP:0000817) | 3.36176100 |
17 | Generalized tonic-clonic seizures (HP:0002069) | 3.28965660 |
18 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.23188551 |
19 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.21255712 |
20 | Excessive salivation (HP:0003781) | 3.14549316 |
21 | Drooling (HP:0002307) | 3.14549316 |
22 | Dialeptic seizures (HP:0011146) | 3.13062922 |
23 | Amyotrophic lateral sclerosis (HP:0007354) | 3.10797520 |
24 | Depression (HP:0000716) | 3.10274280 |
25 | Impaired social interactions (HP:0000735) | 3.03050393 |
26 | Abnormal social behavior (HP:0012433) | 3.03050393 |
27 | Urinary urgency (HP:0000012) | 2.95600037 |
28 | Genetic anticipation (HP:0003743) | 2.94229773 |
29 | Hyperventilation (HP:0002883) | 2.92563654 |
30 | Truncal ataxia (HP:0002078) | 2.90525936 |
31 | Megalencephaly (HP:0001355) | 2.88839694 |
32 | Abnormality of the lower motor neuron (HP:0002366) | 2.88100502 |
33 | Abnormal eating behavior (HP:0100738) | 2.86406287 |
34 | Abnormality of the corticospinal tract (HP:0002492) | 2.82888750 |
35 | Neurofibrillary tangles (HP:0002185) | 2.82653112 |
36 | Gait imbalance (HP:0002141) | 2.81228218 |
37 | Dysdiadochokinesis (HP:0002075) | 2.80491430 |
38 | Postural instability (HP:0002172) | 2.79259198 |
39 | Progressive inability to walk (HP:0002505) | 2.76748695 |
40 | Cerebral inclusion bodies (HP:0100314) | 2.73208658 |
41 | Gaze-evoked nystagmus (HP:0000640) | 2.72652686 |
42 | Spastic gait (HP:0002064) | 2.71467310 |
43 | Hemiparesis (HP:0001269) | 2.70433870 |
44 | Insidious onset (HP:0003587) | 2.65063461 |
45 | Termporal pattern (HP:0011008) | 2.65063461 |
46 | Anxiety (HP:0000739) | 2.63618954 |
47 | Torticollis (HP:0000473) | 2.61435106 |
48 | Dysmetria (HP:0001310) | 2.59650604 |
49 | Limb dystonia (HP:0002451) | 2.59552641 |
50 | Abnormality of binocular vision (HP:0011514) | 2.58529033 |
51 | Diplopia (HP:0000651) | 2.58529033 |
52 | Amblyopia (HP:0000646) | 2.57971262 |
53 | Inappropriate behavior (HP:0000719) | 2.57075224 |
54 | Agitation (HP:0000713) | 2.55736995 |
55 | Intention tremor (HP:0002080) | 2.50759961 |
56 | Impaired smooth pursuit (HP:0007772) | 2.50624561 |
57 | Epileptiform EEG discharges (HP:0011182) | 2.48751286 |
58 | Polyphagia (HP:0002591) | 2.47754124 |
59 | EEG with generalized epileptiform discharges (HP:0011198) | 2.47025610 |
60 | Cortical dysplasia (HP:0002539) | 2.43832781 |
61 | Fetal akinesia sequence (HP:0001989) | 2.43021999 |
62 | Hypsarrhythmia (HP:0002521) | 2.42251018 |
63 | Stereotypic behavior (HP:0000733) | 2.42194665 |
64 | Insomnia (HP:0100785) | 2.37658252 |
65 | Lower limb muscle weakness (HP:0007340) | 2.36786548 |
66 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.34800302 |
67 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.34800302 |
68 | Akinesia (HP:0002304) | 2.33586606 |
69 | Bradykinesia (HP:0002067) | 2.33159230 |
70 | Focal dystonia (HP:0004373) | 2.32732599 |
71 | Abnormality of the labia minora (HP:0012880) | 2.30289426 |
72 | Spastic tetraplegia (HP:0002510) | 2.29738967 |
73 | Apathy (HP:0000741) | 2.24340659 |
74 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.24084342 |
75 | Absent speech (HP:0001344) | 2.22207466 |
76 | Specific learning disability (HP:0001328) | 2.20083850 |
77 | Obstructive sleep apnea (HP:0002870) | 2.19566238 |
78 | Inability to walk (HP:0002540) | 2.18945321 |
79 | Hemiplegia (HP:0002301) | 2.17605497 |
80 | Status epilepticus (HP:0002133) | 2.17286065 |
81 | Scanning speech (HP:0002168) | 2.16754101 |
82 | Retinal dysplasia (HP:0007973) | 2.15668962 |
83 | Pheochromocytoma (HP:0002666) | 2.15157636 |
84 | Pointed chin (HP:0000307) | 2.12974135 |
85 | Exotropia (HP:0000577) | 2.12843133 |
86 | Aqueductal stenosis (HP:0002410) | 2.10549824 |
87 | Medial flaring of the eyebrow (HP:0010747) | 2.10309085 |
88 | Craniofacial dystonia (HP:0012179) | 2.10281152 |
89 | Congenital primary aphakia (HP:0007707) | 2.09929051 |
90 | Sleep apnea (HP:0010535) | 2.09277768 |
91 | Clonus (HP:0002169) | 2.06710713 |
92 | Impaired vibratory sensation (HP:0002495) | 2.06160346 |
93 | Hypoplasia of the corpus callosum (HP:0002079) | 2.04778901 |
94 | Abnormality of salivation (HP:0100755) | 2.02108276 |
95 | Nephrogenic diabetes insipidus (HP:0009806) | 2.01654101 |
96 | Split foot (HP:0001839) | 2.01600329 |
97 | Lower limb amyotrophy (HP:0007210) | 2.00170136 |
98 | Genital tract atresia (HP:0001827) | 1.99225132 |
99 | Macroorchidism (HP:0000053) | 1.98999430 |
100 | Oligodactyly (hands) (HP:0001180) | 1.97958728 |
101 | Vaginal atresia (HP:0000148) | 1.97752585 |
102 | Diminished motivation (HP:0000745) | 1.96978542 |
103 | Ventricular fibrillation (HP:0001663) | 1.96156723 |
104 | Ankyloglossia (HP:0010296) | 1.96099133 |
105 | Blue irides (HP:0000635) | 1.95502923 |
106 | Hepatoblastoma (HP:0002884) | 1.92543272 |
107 | Optic nerve hypoplasia (HP:0000609) | 1.91278044 |
108 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.90229427 |
109 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.90122072 |
110 | Hypoplasia of the brainstem (HP:0002365) | 1.90122072 |
111 | Generalized myoclonic seizures (HP:0002123) | 1.88902352 |
112 | Peripheral hypomyelination (HP:0007182) | 1.85460140 |
113 | True hermaphroditism (HP:0010459) | 1.84818418 |
114 | Neuronal loss in central nervous system (HP:0002529) | 1.84705435 |
115 | Esotropia (HP:0000565) | 1.84323115 |
116 | Intellectual disability, profound (HP:0002187) | 1.84305457 |
117 | Nephronophthisis (HP:0000090) | 1.83717201 |
118 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.82145516 |
119 | Lissencephaly (HP:0001339) | 1.80838074 |
120 | Pachygyria (HP:0001302) | 1.80591598 |
121 | Protruding tongue (HP:0010808) | 1.80558022 |
122 | Dysmetric saccades (HP:0000641) | 1.79589491 |
123 | Muscular hypotonia of the trunk (HP:0008936) | 1.78319766 |
124 | Failure to thrive in infancy (HP:0001531) | 1.77817652 |
125 | Cutaneous finger syndactyly (HP:0010554) | 1.76826890 |
126 | Intellectual disability, severe (HP:0010864) | 1.75423167 |
127 | Gait ataxia (HP:0002066) | 1.75058088 |
128 | Neuroendocrine neoplasm (HP:0100634) | 1.74973213 |
129 | Intestinal atresia (HP:0011100) | 1.72123889 |
130 | Renal hypoplasia (HP:0000089) | 1.67879559 |
131 | Pancreatic fibrosis (HP:0100732) | 1.64803945 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * MARK1 | 4.65986896 |
2 | MAP3K9 | 4.13989640 |
3 | NTRK3 | 4.00746490 |
4 | EPHA4 | 3.56790328 |
5 | MAP3K4 | 2.97360673 |
6 | MINK1 | 2.83385958 |
7 | NTRK2 | 2.76159552 |
8 | MAP2K7 | 2.40866333 |
9 | DAPK2 | 2.40622677 |
10 | PAK6 | 2.28653713 |
11 | PRKD3 | 1.93908557 |
12 | KSR1 | 1.90799403 |
13 | KSR2 | 1.89130401 |
14 | CAMKK1 | 1.89075942 |
15 | MAPK13 | 1.81608627 |
16 | NTRK1 | 1.79026998 |
17 | MAP2K4 | 1.72226182 |
18 | PHKG1 | 1.67126217 |
19 | PHKG2 | 1.67126217 |
20 | TNIK | 1.63426715 |
21 | CDK5 | 1.59438188 |
22 | SIK2 | 1.51665333 |
23 | CASK | 1.48476442 |
24 | TYRO3 | 1.39585665 |
25 | LATS2 | 1.39035789 |
26 | DAPK1 | 1.31323074 |
27 | MAP3K2 | 1.28317634 |
28 | MAP3K12 | 1.25312521 |
29 | TRIM28 | 1.23662413 |
30 | UHMK1 | 1.21375852 |
31 | ERBB3 | 1.18833616 |
32 | PLK2 | 1.15691751 |
33 | TAOK1 | 1.15001342 |
34 | EPHA3 | 1.11670753 |
35 | STK38 | 1.10954800 |
36 | PRKCG | 1.10541026 |
37 | EPHB2 | 1.09875403 |
38 | CSNK1G2 | 1.08050053 |
39 | PRPF4B | 1.06158027 |
40 | RET | 1.01594850 |
41 | DYRK2 | 1.00760500 |
42 | SCYL2 | 0.97544572 |
43 | PNCK | 0.97391317 |
44 | PAK3 | 0.96653764 |
45 | STK11 | 0.95876186 |
46 | GRK5 | 0.95730779 |
47 | CDK19 | 0.94127565 |
48 | CDK18 | 0.93987485 |
49 | CDK15 | 0.92414208 |
50 | CSNK1G1 | 0.90302155 |
51 | FES | 0.89623775 |
52 | MARK2 | 0.89576121 |
53 | RIPK4 | 0.89442118 |
54 | CDK14 | 0.89366384 |
55 | CAMKK2 | 0.88979854 |
56 | MAP4K2 | 0.87147002 |
57 | ALK | 0.87111061 |
58 | DYRK1A | 0.82700658 |
59 | SGK223 | 0.82616552 |
60 | SGK494 | 0.82616552 |
61 | FRK | 0.80607831 |
62 | CDK11A | 0.80005499 |
63 | CAMK2A | 0.79860348 |
64 | PRKCH | 0.79137485 |
65 | WNK3 | 0.73855829 |
66 | LMTK2 | 0.71394036 |
67 | CAMK1 | 0.71348151 |
68 | FGFR2 | 0.70230395 |
69 | PRKCZ | 0.69038385 |
70 | SGK2 | 0.66578174 |
71 | SGK1 | 0.66115314 |
72 | SGK3 | 0.63182066 |
73 | CAMK1G | 0.62658601 |
74 | DYRK3 | 0.57829612 |
75 | CAMK2B | 0.57228922 |
76 | RAF1 | 0.56794473 |
77 | PKN1 | 0.54759406 |
78 | RIPK1 | 0.54282310 |
79 | DYRK1B | 0.52645372 |
80 | MAP3K6 | 0.52413176 |
81 | BMPR1B | 0.52100214 |
82 | RPS6KA2 | 0.51979766 |
83 | CDC42BPA | 0.51684029 |
84 | * RPS6KA3 | 0.48711915 |
85 | CAMK2G | 0.46958301 |
86 | MKNK2 | 0.46869371 |
87 | CCNB1 | 0.46842668 |
88 | PDK1 | 0.46260354 |
89 | CSNK1G3 | 0.46105985 |
90 | CSNK1A1L | 0.44228492 |
91 | * FYN | 0.43872368 |
92 | MAPK10 | 0.43513039 |
93 | BRSK1 | 0.43413935 |
94 | ERBB2 | 0.43290337 |
95 | PRKCE | 0.42973154 |
96 | CSNK1E | 0.42824442 |
97 | LIMK1 | 0.42475825 |
98 | CDK3 | 0.42464864 |
99 | ARAF | 0.42227401 |
100 | PDPK1 | 0.42089157 |
101 | BRD4 | 0.41938576 |
102 | NEK1 | 0.41276301 |
103 | PRKG1 | 0.40028374 |
104 | INSRR | 0.39902705 |
105 | CAMK2D | 0.39754717 |
106 | PINK1 | 0.39538713 |
107 | AKT3 | 0.38604736 |
108 | ICK | 0.38106560 |
109 | ADRBK2 | 0.37574733 |
110 | CSNK1A1 | 0.36677722 |
111 | MAPK12 | 0.36425964 |
112 | ROCK2 | 0.35913027 |
113 | MAP3K13 | 0.35779761 |
114 | PDGFRA | 0.35670282 |
115 | BCR | 0.35017081 |
116 | STK39 | 0.34779767 |
117 | OXSR1 | 0.34722399 |
118 | RPS6KA4 | 0.34603951 |
119 | * PRKACA | 0.33891475 |
120 | PRKACB | 0.33688427 |
121 | MAP3K1 | 0.33194076 |
122 | CAMK4 | 0.33005719 |
123 | * CSNK1D | 0.33003688 |
124 | PRKCB | 0.32435941 |
125 | FER | 0.32334065 |
126 | WNK4 | 0.31634241 |
127 | MAPK9 | 0.31283253 |
128 | ROCK1 | 0.31124927 |
129 | DMPK | 0.31040612 |
130 | MAPK8 | 0.30731722 |
131 | PRKAA1 | 0.29958389 |
132 | * GSK3B | 0.29352609 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.38188974 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.99701344 |
3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.67298108 |
4 | Circadian entrainment_Homo sapiens_hsa04713 | 2.65173863 |
5 | Olfactory transduction_Homo sapiens_hsa04740 | 2.64397820 |
6 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.51933180 |
7 | Long-term potentiation_Homo sapiens_hsa04720 | 2.48405311 |
8 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.47600946 |
9 | Morphine addiction_Homo sapiens_hsa05032 | 2.39734192 |
10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.23782479 |
11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.23554514 |
12 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.18708139 |
13 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.98194836 |
14 | Salivary secretion_Homo sapiens_hsa04970 | 1.97583118 |
15 | Insulin secretion_Homo sapiens_hsa04911 | 1.97310799 |
16 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.84635511 |
17 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.79902154 |
18 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.78197649 |
19 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.69070773 |
20 | Cocaine addiction_Homo sapiens_hsa05030 | 1.67213476 |
21 | Renin secretion_Homo sapiens_hsa04924 | 1.64229599 |
22 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.61333175 |
23 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.60335981 |
24 | Long-term depression_Homo sapiens_hsa04730 | 1.58184144 |
25 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.53222354 |
26 | Taste transduction_Homo sapiens_hsa04742 | 1.51519995 |
27 | Axon guidance_Homo sapiens_hsa04360 | 1.50436444 |
28 | Gap junction_Homo sapiens_hsa04540 | 1.46760142 |
29 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.45605217 |
30 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.40978075 |
31 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.36866667 |
32 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.35206112 |
33 | Glioma_Homo sapiens_hsa05214 | 1.31250749 |
34 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.29285481 |
35 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.25961803 |
36 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.22741566 |
37 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.22412310 |
38 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.20157942 |
39 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.12419855 |
40 | Melanogenesis_Homo sapiens_hsa04916 | 1.08406456 |
41 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.06432827 |
42 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.01215288 |
43 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.99747451 |
44 | Phototransduction_Homo sapiens_hsa04744 | 0.99120126 |
45 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.98571254 |
46 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.95764874 |
47 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.94331062 |
48 | Endometrial cancer_Homo sapiens_hsa05213 | 0.92199579 |
49 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.91361488 |
50 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.88103788 |
51 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.84471003 |
52 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.83531277 |
53 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.80870613 |
54 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.80765562 |
55 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.80316593 |
56 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.80048028 |
57 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.79012358 |
58 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.78146012 |
59 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.77002778 |
60 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.74346809 |
61 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.74173153 |
62 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.73516234 |
63 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.73081438 |
64 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.71104960 |
65 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.70160775 |
66 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.69363937 |
67 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.68623768 |
68 | Colorectal cancer_Homo sapiens_hsa05210 | 0.67731706 |
69 | Alcoholism_Homo sapiens_hsa05034 | 0.66003446 |
70 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.65606934 |
71 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.64867266 |
72 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.64504957 |
73 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.64357491 |
74 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.64264024 |
75 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.62484406 |
76 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.62289264 |
77 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.61643663 |
78 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.61219455 |
79 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.60494512 |
80 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.59974229 |
81 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.59877699 |
82 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.59435633 |
83 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.58167687 |
84 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.57567385 |
85 | Endocytosis_Homo sapiens_hsa04144 | 0.57247488 |
86 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.57061202 |
87 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.55794775 |
88 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.55677931 |
89 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.53632156 |
90 | Prion diseases_Homo sapiens_hsa05020 | 0.53153560 |
91 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.51796987 |
92 | Alzheimers disease_Homo sapiens_hsa05010 | 0.51750068 |
93 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.49353395 |
94 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.49316955 |
95 | Bile secretion_Homo sapiens_hsa04976 | 0.48759570 |
96 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.47595128 |
97 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.47025923 |
98 | Circadian rhythm_Homo sapiens_hsa04710 | 0.45726278 |
99 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.43353902 |
100 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.41246289 |
101 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.40858981 |
102 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40852148 |
103 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.40838224 |
104 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.40280695 |
105 | Parkinsons disease_Homo sapiens_hsa05012 | 0.39680418 |
106 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.39556444 |
107 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.38877190 |
108 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.37742334 |
109 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.37042607 |
110 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.36709317 |
111 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.36701151 |
112 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.35791854 |
113 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.32419690 |
114 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.32235025 |
115 | Tight junction_Homo sapiens_hsa04530 | 0.32074374 |
116 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.30388371 |
117 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.29403368 |
118 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.28488905 |