Rank | Gene Set | Z-score |
---|---|---|
1 | detection of molecule of bacterial origin (GO:0032490) | 5.61436537 |
2 | cellular extravasation (GO:0045123) | 4.60871692 |
3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.49872560 |
4 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.41962601 |
5 | detection of external biotic stimulus (GO:0098581) | 4.29329806 |
6 | microglial cell activation (GO:0001774) | 4.14692426 |
7 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.09970937 |
8 | detection of other organism (GO:0098543) | 4.03519883 |
9 | macrophage activation (GO:0042116) | 3.86670669 |
10 | neutrophil activation involved in immune response (GO:0002283) | 3.84623740 |
11 | neutrophil mediated immunity (GO:0002446) | 3.77810221 |
12 | detection of biotic stimulus (GO:0009595) | 3.74245463 |
13 | growth hormone receptor signaling pathway (GO:0060396) | 3.73734846 |
14 | response to peptidoglycan (GO:0032494) | 3.64872045 |
15 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.62783620 |
16 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.60763466 |
17 | response to host immune response (GO:0052572) | 3.53356263 |
18 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.53356263 |
19 | negative regulation of interleukin-12 production (GO:0032695) | 3.46301759 |
20 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.40635371 |
21 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.34854858 |
22 | response to host (GO:0075136) | 3.34854858 |
23 | response to host defenses (GO:0052200) | 3.34854858 |
24 | detection of bacterium (GO:0016045) | 3.34606846 |
25 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.25504315 |
26 | myeloid leukocyte mediated immunity (GO:0002444) | 3.23926265 |
27 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.22696979 |
28 | negative regulation of cell killing (GO:0031342) | 3.22696979 |
29 | cellular response to growth hormone stimulus (GO:0071378) | 3.16899239 |
30 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.16734698 |
31 | neutrophil activation (GO:0042119) | 3.15943838 |
32 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.05717786 |
33 | B cell receptor signaling pathway (GO:0050853) | 3.05349015 |
34 | hepatocyte apoptotic process (GO:0097284) | 3.00119842 |
35 | positive regulation of mast cell activation (GO:0033005) | 2.99054953 |
36 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.97385793 |
37 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.97385793 |
38 | negative regulation of T cell mediated immunity (GO:0002710) | 2.94543017 |
39 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.91849269 |
40 | response to interleukin-15 (GO:0070672) | 2.91700687 |
41 | T-helper 1 type immune response (GO:0042088) | 2.90827160 |
42 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.89231414 |
43 | myeloid cell activation involved in immune response (GO:0002275) | 2.87657379 |
44 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.84450197 |
45 | granulocyte activation (GO:0036230) | 2.82406392 |
46 | positive regulation of interferon-alpha production (GO:0032727) | 2.81277214 |
47 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.79968014 |
48 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.75676245 |
49 | regulation of mast cell activation (GO:0033003) | 2.73540794 |
50 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.71345379 |
51 | negative regulation of B cell mediated immunity (GO:0002713) | 2.71345379 |
52 | respiratory burst (GO:0045730) | 2.70309374 |
53 | dendritic cell migration (GO:0036336) | 2.67648068 |
54 | positive regulation of p38MAPK cascade (GO:1900745) | 2.67632172 |
55 | germinal center formation (GO:0002467) | 2.67039961 |
56 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.67002358 |
57 | activated T cell proliferation (GO:0050798) | 2.66843361 |
58 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.66770121 |
59 | positive regulation of granulocyte differentiation (GO:0030854) | 2.66525392 |
60 | positive regulation of leukocyte degranulation (GO:0043302) | 2.65298528 |
61 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.64714753 |
62 | leukocyte aggregation (GO:0070486) | 2.63187324 |
63 | positive regulation of histone deacetylation (GO:0031065) | 2.62302894 |
64 | regulation of tolerance induction (GO:0002643) | 2.61571413 |
65 | negative thymic T cell selection (GO:0045060) | 2.58240573 |
66 | negative T cell selection (GO:0043383) | 2.57900082 |
67 | regulation of interferon-alpha production (GO:0032647) | 2.57854186 |
68 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.57782902 |
69 | positive regulation of mast cell degranulation (GO:0043306) | 2.57782902 |
70 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.56728182 |
71 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.56649297 |
72 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.55310926 |
73 | regulation of mast cell degranulation (GO:0043304) | 2.54690349 |
74 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.54278152 |
75 | interleukin-6-mediated signaling pathway (GO:0070102) | 2.53894376 |
76 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.53567101 |
77 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.53500303 |
78 | protein localization to endosome (GO:0036010) | 2.53473619 |
79 | negative regulation of adaptive immune response (GO:0002820) | 2.51927700 |
80 | cellular response to interleukin-15 (GO:0071350) | 2.50951981 |
81 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.49724581 |
82 | negative regulation of complement activation (GO:0045916) | 2.49536150 |
83 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.48957368 |
84 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.48918381 |
85 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.48519221 |
86 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.47219622 |
87 | phospholipid efflux (GO:0033700) | 2.46945996 |
88 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.43859617 |
89 | establishment of protein localization to Golgi (GO:0072600) | 2.42172493 |
90 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.42087873 |
91 | protein targeting to Golgi (GO:0000042) | 2.41869447 |
92 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.40673403 |
93 | cell adhesion mediated by integrin (GO:0033627) | 2.40344758 |
94 | regulation of gamma-delta T cell activation (GO:0046643) | 2.39365213 |
95 | regulation of cholesterol homeostasis (GO:2000188) | 2.38028143 |
96 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.33718301 |
97 | positive regulation by symbiont of host defense response (GO:0052509) | 2.31541091 |
98 | modulation by symbiont of host defense response (GO:0052031) | 2.31541091 |
99 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.31541091 |
100 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.31541091 |
101 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.31541091 |
102 | modulation by symbiont of host immune response (GO:0052553) | 2.31541091 |
103 | macroautophagy (GO:0016236) | 2.30508912 |
104 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.29412542 |
105 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.25494980 |
106 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.25494980 |
107 | positive regulation of glycolytic process (GO:0045821) | 2.25404528 |
108 | histone H3-K36 demethylation (GO:0070544) | 2.25247835 |
109 | positive thymic T cell selection (GO:0045059) | 2.24332342 |
110 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.21169126 |
111 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.20722371 |
112 | cellular response to ethanol (GO:0071361) | 2.20458020 |
113 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.20330248 |
114 | macrophage activation involved in immune response (GO:0002281) | 2.17911251 |
115 | protein-lipid complex assembly (GO:0065005) | 2.17365561 |
116 | I-kappaB phosphorylation (GO:0007252) | 2.16459571 |
117 | plasma lipoprotein particle assembly (GO:0034377) | 2.15061016 |
118 | phospholipid homeostasis (GO:0055091) | 2.13468788 |
119 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.12688776 |
120 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.12688776 |
121 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.12688776 |
122 | positive T cell selection (GO:0043368) | 2.11519621 |
123 | negative regulation of fatty acid transport (GO:2000192) | 2.08721343 |
124 | phospholipid translocation (GO:0045332) | 2.06810388 |
125 | lipid translocation (GO:0034204) | 2.06810388 |
126 | regulation of ARF protein signal transduction (GO:0032012) | 2.06008900 |
127 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.05881649 |
128 | lipoprotein transport (GO:0042953) | 2.04882783 |
129 | regulation of beta-amyloid formation (GO:1902003) | 2.02875233 |
130 | cholesterol efflux (GO:0033344) | 2.01944932 |
131 | apoptotic cell clearance (GO:0043277) | 2.01843184 |
132 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.00319371 |
133 | T-helper cell differentiation (GO:0042093) | 2.00319371 |
134 | positive regulation of glycogen metabolic process (GO:0070875) | 1.99514033 |
135 | positive regulation of cholesterol efflux (GO:0010875) | 1.98326409 |
136 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 1.97484059 |
137 | regulation of T cell tolerance induction (GO:0002664) | 1.96656048 |
138 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 1.96290143 |
139 | regulation of p38MAPK cascade (GO:1900744) | 1.95724794 |
140 | protein carboxylation (GO:0018214) | 1.95311071 |
141 | peptidyl-glutamic acid carboxylation (GO:0017187) | 1.95311071 |
142 | heterotypic cell-cell adhesion (GO:0034113) | 1.94117145 |
143 | response to growth hormone (GO:0060416) | 1.94087607 |
144 | substrate-dependent cell migration (GO:0006929) | 1.93324097 |
145 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 1.92863919 |
146 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 1.92138093 |
147 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 1.91192984 |
148 | positive regulation of cholesterol transport (GO:0032376) | 1.90982291 |
149 | positive regulation of sterol transport (GO:0032373) | 1.90982291 |
150 | negative regulation of B cell proliferation (GO:0030889) | 1.90778327 |
151 | reverse cholesterol transport (GO:0043691) | 1.90412152 |
152 | response to lipoprotein particle (GO:0055094) | 1.90183058 |
153 | positive regulation of fatty acid oxidation (GO:0046321) | 1.89482681 |
154 | endoplasmic reticulum organization (GO:0007029) | 1.87585031 |
155 | response to laminar fluid shear stress (GO:0034616) | 1.87573977 |
156 | nerve growth factor signaling pathway (GO:0038180) | 1.86776301 |
157 | response to fluid shear stress (GO:0034405) | 1.86718419 |
158 | negative regulation of bone resorption (GO:0045779) | 1.85104132 |
159 | gland morphogenesis (GO:0022612) | 1.84329179 |
160 | iron ion import (GO:0097286) | 1.83908661 |
161 | positive regulation of astrocyte differentiation (GO:0048711) | 1.81863737 |
162 | regulation of extracellular matrix disassembly (GO:0010715) | 1.81131782 |
163 | regulation of fatty acid beta-oxidation (GO:0031998) | 1.81118065 |
164 | COPII vesicle coating (GO:0048208) | 1.80889755 |
165 | germ cell migration (GO:0008354) | 1.80655059 |
166 | lipoprotein metabolic process (GO:0042157) | 1.78197231 |
167 | low-density lipoprotein particle clearance (GO:0034383) | 1.77783434 |
168 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 1.77338061 |
169 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 1.76915333 |
170 | regulation of bile acid biosynthetic process (GO:0070857) | 1.76456321 |
171 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 1.76429668 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.74035234 |
2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.02668065 |
3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.62389237 |
4 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.40838478 |
5 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.38991137 |
6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.29163653 |
7 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.00718602 |
8 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.99885748 |
9 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.96791891 |
10 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.93847915 |
11 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.86590979 |
12 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.85346736 |
13 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.84618040 |
14 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.80795688 |
15 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.77384994 |
16 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.76880426 |
17 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.70036715 |
18 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.69419066 |
19 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.67349392 |
20 | MYB_26560356_Chip-Seq_TH2_Human | 1.64278456 |
21 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.63926391 |
22 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.63650138 |
23 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.63637254 |
24 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.63043231 |
25 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.62031396 |
26 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.59397587 |
27 | TP53_16413492_ChIP-PET_HCT116_Human | 1.57126154 |
28 | GATA1_22025678_ChIP-Seq_K562_Human | 1.55992704 |
29 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.54383968 |
30 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.54339350 |
31 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.51632759 |
32 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.50097251 |
33 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.45127155 |
34 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.44044242 |
35 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.41368278 |
36 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.41131786 |
37 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.40205883 |
38 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.40205883 |
39 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.39176666 |
40 | SPI1_23127762_ChIP-Seq_K562_Human | 1.37918326 |
41 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.37645013 |
42 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.37276177 |
43 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.35548592 |
44 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.35083874 |
45 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.33450737 |
46 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.31721995 |
47 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.31130569 |
48 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.30828224 |
49 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.30269951 |
50 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.30170953 |
51 | MYB_26560356_Chip-Seq_TH1_Human | 1.30039235 |
52 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.29785433 |
53 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.29454575 |
54 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.28854202 |
55 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.28828704 |
56 | CJUN_26792858_Chip-Seq_BT549_Human | 1.28448051 |
57 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.27558693 |
58 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.27264174 |
59 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.24065407 |
60 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.23454896 |
61 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.22586752 |
62 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.21316783 |
63 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.21169174 |
64 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.20806046 |
65 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.20791041 |
66 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.20136713 |
67 | GATA3_26560356_Chip-Seq_TH2_Human | 1.20035890 |
68 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.18036850 |
69 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.15744251 |
70 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.15475085 |
71 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.13308647 |
72 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.11709508 |
73 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.10574562 |
74 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.10149294 |
75 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.09546435 |
76 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.08425072 |
77 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.06985419 |
78 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.06978310 |
79 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.06208249 |
80 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.05866129 |
81 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.05315329 |
82 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.04985218 |
83 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.03810971 |
84 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.03248004 |
85 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.03143746 |
86 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.01246765 |
87 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.00920996 |
88 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.00349917 |
89 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.99702238 |
90 | RXR_22108803_ChIP-Seq_LS180_Human | 0.99552023 |
91 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.99393220 |
92 | * SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.99169170 |
93 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.98760437 |
94 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98640691 |
95 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.98320119 |
96 | * TP63_23658742_ChIP-Seq_EP156T_Human | 0.98320076 |
97 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.97963712 |
98 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.97109342 |
99 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.96931794 |
100 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.96487584 |
101 | STAT3_23295773_ChIP-Seq_U87_Human | 0.96198650 |
102 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.96168103 |
103 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.95999977 |
104 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.95372337 |
105 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.95179447 |
106 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.95069483 |
107 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.94796980 |
108 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.94781043 |
109 | GATA1_19941826_ChIP-Seq_K562_Human | 0.94625419 |
110 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.94569586 |
111 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.94013014 |
112 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.93853849 |
113 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.93575616 |
114 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.93414825 |
115 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.93363872 |
116 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.93254249 |
117 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.93249350 |
118 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.93249350 |
119 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.92991862 |
120 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.92873012 |
121 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.92420203 |
122 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.92358834 |
123 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.91898818 |
124 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.91774584 |
125 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.91107260 |
126 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.90916710 |
127 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.90454154 |
128 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.90262185 |
129 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.90211652 |
130 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.88918992 |
131 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.88889156 |
132 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.88587786 |
133 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.88513848 |
134 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.87378544 |
135 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.87182913 |
136 | * GATA2_19941826_ChIP-Seq_K562_Human | 0.86816806 |
137 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.86814487 |
138 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.86614530 |
139 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.85227598 |
140 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.84855355 |
141 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.84331181 |
142 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.83952158 |
143 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.83085345 |
144 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82449626 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003300_gastrointestinal_ulcer | 3.51308363 |
2 | MP0000569_abnormal_digit_pigmentation | 3.32940095 |
3 | MP0008057_abnormal_DNA_replication | 2.56669626 |
4 | MP0002877_abnormal_melanocyte_morpholog | 2.51258186 |
5 | MP0003252_abnormal_bile_duct | 2.49167618 |
6 | MP0003183_abnormal_peptide_metabolism | 2.46710964 |
7 | MP0003303_peritoneal_inflammation | 2.46101153 |
8 | MP0010234_abnormal_vibrissa_follicle | 2.43847147 |
9 | MP0005360_urolithiasis | 2.38451829 |
10 | MP0002166_altered_tumor_susceptibility | 2.36839807 |
11 | MP0002139_abnormal_hepatobiliary_system | 2.26026461 |
12 | MP0009780_abnormal_chondrocyte_physiolo | 2.24277954 |
13 | MP0008438_abnormal_cutaneous_collagen | 2.22391086 |
14 | MP0002254_reproductive_system_inflammat | 2.10323419 |
15 | MP0002009_preneoplasia | 2.03243576 |
16 | MP0003705_abnormal_hypodermis_morpholog | 1.99817723 |
17 | MP0009785_altered_susceptibility_to | 1.98106476 |
18 | MP0003045_fibrosis | 1.97200640 |
19 | MP0005365_abnormal_bile_salt | 1.91024532 |
20 | MP0008260_abnormal_autophagy | 1.90255029 |
21 | MP0002138_abnormal_hepatobiliary_system | 1.89862601 |
22 | MP0003828_pulmonary_edema | 1.81270557 |
23 | MP0003787_abnormal_imprinting | 1.80055042 |
24 | MP0004883_abnormal_blood_vessel | 1.78238379 |
25 | MP0001835_abnormal_antigen_presentation | 1.77761445 |
26 | MP0004381_abnormal_hair_follicle | 1.72774962 |
27 | MP0003656_abnormal_erythrocyte_physiolo | 1.70944992 |
28 | MP0005076_abnormal_cell_differentiation | 1.66260293 |
29 | MP0005387_immune_system_phenotype | 1.64108409 |
30 | MP0001790_abnormal_immune_system | 1.64108409 |
31 | MP0002928_abnormal_bile_duct | 1.59531523 |
32 | MP0004947_skin_inflammation | 1.58731498 |
33 | MP0010352_gastrointestinal_tract_polyps | 1.57622604 |
34 | MP0002006_tumorigenesis | 1.57499162 |
35 | MP0003436_decreased_susceptibility_to | 1.57104026 |
36 | MP0002396_abnormal_hematopoietic_system | 1.56087934 |
37 | MP0005085_abnormal_gallbladder_physiolo | 1.52831860 |
38 | MP0002998_abnormal_bone_remodeling | 1.52569069 |
39 | MP0002148_abnormal_hypersensitivity_rea | 1.50743171 |
40 | MP0008961_abnormal_basal_metabolism | 1.49967089 |
41 | MP0003172_abnormal_lysosome_physiology | 1.49711673 |
42 | MP0005451_abnormal_body_composition | 1.49453552 |
43 | MP0005275_abnormal_skin_tensile | 1.48775494 |
44 | MP0005164_abnormal_response_to | 1.46802943 |
45 | MP0001666_abnormal_nutrient_absorption | 1.46523034 |
46 | MP0003091_abnormal_cell_migration | 1.45118528 |
47 | MP0010329_abnormal_lipoprotein_level | 1.43137626 |
48 | MP0003690_abnormal_glial_cell | 1.39755586 |
49 | MP0003868_abnormal_feces_composition | 1.39075379 |
50 | * MP0000716_abnormal_immune_system | 1.34528668 |
51 | MP0004130_abnormal_muscle_cell | 1.34194924 |
52 | MP0000015_abnormal_ear_pigmentation | 1.32574770 |
53 | * MP0002398_abnormal_bone_marrow | 1.31602596 |
54 | MP0009384_cardiac_valve_regurgitation | 1.30229821 |
55 | MP0000604_amyloidosis | 1.25714260 |
56 | MP0002419_abnormal_innate_immunity | 1.25698294 |
57 | MP0005000_abnormal_immune_tolerance | 1.25591144 |
58 | MP0002896_abnormal_bone_mineralization | 1.24643548 |
59 | MP0003279_aneurysm | 1.23676105 |
60 | MP0000689_abnormal_spleen_morphology | 1.22787778 |
61 | MP0008875_abnormal_xenobiotic_pharmacok | 1.22625010 |
62 | MP0005075_abnormal_melanosome_morpholog | 1.22475179 |
63 | MP0003724_increased_susceptibility_to | 1.22415862 |
64 | MP0001851_eye_inflammation | 1.22356377 |
65 | MP0001800_abnormal_humoral_immune | 1.21987720 |
66 | MP0003191_abnormal_cellular_cholesterol | 1.20870379 |
67 | MP0005310_abnormal_salivary_gland | 1.19580160 |
68 | MP0000685_abnormal_immune_system | 1.16896331 |
69 | MP0001533_abnormal_skeleton_physiology | 1.16000308 |
70 | MP0002452_abnormal_antigen_presenting | 1.15896329 |
71 | MP0000609_abnormal_liver_physiology | 1.14436286 |
72 | MP0006054_spinal_hemorrhage | 1.13501335 |
73 | MP0004510_myositis | 1.13360422 |
74 | MP0002722_abnormal_immune_system | 1.12196723 |
75 | MP0000371_diluted_coat_color | 1.12073420 |
76 | MP0004808_abnormal_hematopoietic_stem | 1.10658497 |
77 | MP0005397_hematopoietic_system_phenotyp | 1.09834876 |
78 | MP0001545_abnormal_hematopoietic_system | 1.09834876 |
79 | MP0002168_other_aberrant_phenotype | 1.09508812 |
80 | MP0006082_CNS_inflammation | 1.08555838 |
81 | MP0003566_abnormal_cell_adhesion | 1.07508778 |
82 | MP0010155_abnormal_intestine_physiology | 1.07124278 |
83 | MP0008469_abnormal_protein_level | 1.07078449 |
84 | MP0009764_decreased_sensitivity_to | 1.06305744 |
85 | * MP0002723_abnormal_immune_serum | 1.05002963 |
86 | MP0005174_abnormal_tail_pigmentation | 1.04919096 |
87 | MP0002277_abnormal_respiratory_mucosa | 1.04842501 |
88 | MP0000703_abnormal_thymus_morphology | 1.04791254 |
89 | MP0005220_abnormal_exocrine_pancreas | 1.03436770 |
90 | MP0002060_abnormal_skin_morphology | 1.02616546 |
91 | MP0000427_abnormal_hair_cycle | 1.02518197 |
92 | MP0002909_abnormal_adrenal_gland | 1.01957079 |
93 | MP0010678_abnormal_skin_adnexa | 1.01182135 |
94 | MP0001853_heart_inflammation | 0.99416125 |
95 | MP0001299_abnormal_eye_distance/ | 0.99125605 |
96 | MP0009278_abnormal_bone_marrow | 0.98749377 |
97 | MP0005671_abnormal_response_to | 0.98524781 |
98 | MP0000013_abnormal_adipose_tissue | 0.97181132 |
99 | MP0003453_abnormal_keratinocyte_physiol | 0.96380003 |
100 | MP0005464_abnormal_platelet_physiology | 0.95797381 |
101 | * MP0002429_abnormal_blood_cell | 0.93802745 |
102 | MP0004185_abnormal_adipocyte_glucose | 0.93756572 |
103 | MP0000465_gastrointestinal_hemorrhage | 0.93403933 |
104 | MP0001845_abnormal_inflammatory_respons | 0.91996233 |
105 | MP0005058_abnormal_lysosome_morphology | 0.91497523 |
106 | * MP0001819_abnormal_immune_cell | 0.91198560 |
107 | * MP0002420_abnormal_adaptive_immunity | 0.91100845 |
108 | MP0001944_abnormal_pancreas_morphology | 0.90706638 |
109 | MP0004484_altered_response_of | 0.90132663 |
110 | MP0001958_emphysema | 0.89706406 |
111 | MP0003221_abnormal_cardiomyocyte_apopto | 0.89510468 |
112 | MP0009115_abnormal_fat_cell | 0.89302575 |
113 | MP0005409_darkened_coat_color | 0.89211763 |
114 | MP0002090_abnormal_vision | 0.89187583 |
115 | MP0000383_abnormal_hair_follicle | 0.88791621 |
116 | MP0008877_abnormal_DNA_methylation | 0.88767865 |
117 | MP0005334_abnormal_fat_pad | 0.88574387 |
118 | MP0002132_abnormal_respiratory_system | 0.87650149 |
119 | MP0002693_abnormal_pancreas_physiology | 0.87405818 |
120 | MP0002933_joint_inflammation | 0.86870787 |
121 | MP0002971_abnormal_brown_adipose | 0.86412188 |
122 | MP0003195_calcinosis | 0.85515498 |
123 | MP0003795_abnormal_bone_structure | 0.84736572 |
124 | MP0005666_abnormal_adipose_tissue | 0.83162258 |
125 | MP0005166_decreased_susceptibility_to | 0.82726486 |
126 | MP0002118_abnormal_lipid_homeostasis | 0.81976884 |
127 | MP0001879_abnormal_lymphatic_vessel | 0.79880986 |
128 | MP0003448_altered_tumor_morphology | 0.79794991 |
129 | MP0005375_adipose_tissue_phenotype | 0.78850049 |
130 | MP0002405_respiratory_system_inflammati | 0.78844500 |
131 | MP0001873_stomach_inflammation | 0.78476926 |
132 | MP0003866_abnormal_defecation | 0.76816380 |
133 | MP0009840_abnormal_foam_cell | 0.76488357 |
134 | MP0000249_abnormal_blood_vessel | 0.75462304 |
135 | MP0005257_abnormal_intraocular_pressure | 0.74525793 |
136 | MP0003075_altered_response_to | 0.74021443 |
137 | MP0005025_abnormal_response_to | 0.73499520 |
138 | MP0000858_altered_metastatic_potential | 0.72989062 |
139 | MP0003763_abnormal_thymus_physiology | 0.72449179 |
140 | MP0004019_abnormal_vitamin_homeostasis | 0.71985067 |
141 | MP0010368_abnormal_lymphatic_system | 0.71679635 |
142 | MP0005670_abnormal_white_adipose | 0.71677173 |
143 | MP0005376_homeostasis/metabolism_phenot | 0.67917333 |
144 | MP0002332_abnormal_exercise_endurance | 0.67075166 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 4.54678950 |
2 | Papillary thyroid carcinoma (HP:0002895) | 3.60198989 |
3 | Abnormality of macrophages (HP:0004311) | 3.52178065 |
4 | Stomatitis (HP:0010280) | 3.38700660 |
5 | Myocardial infarction (HP:0001658) | 3.30613289 |
6 | Recurrent skin infections (HP:0001581) | 3.25689790 |
7 | Keratoconjunctivitis sicca (HP:0001097) | 2.92641660 |
8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.90354638 |
9 | Mediastinal lymphadenopathy (HP:0100721) | 2.81204029 |
10 | Recurrent cutaneous fungal infections (HP:0011370) | 2.73054219 |
11 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.73054219 |
12 | Hematochezia (HP:0002573) | 2.69308221 |
13 | Keratoconjunctivitis (HP:0001096) | 2.68146966 |
14 | Cerebral aneurysm (HP:0004944) | 2.65752323 |
15 | Xanthomatosis (HP:0000991) | 2.62207653 |
16 | Macroorchidism (HP:0000053) | 2.62179269 |
17 | Mitral valve prolapse (HP:0001634) | 2.61832199 |
18 | Aortic aneurysm (HP:0004942) | 2.58197065 |
19 | Subacute progressive viral hepatitis (HP:0006572) | 2.54541037 |
20 | Pulmonary infiltrates (HP:0002113) | 2.51035419 |
21 | Chest pain (HP:0100749) | 2.50573886 |
22 | Hemoptysis (HP:0002105) | 2.48888434 |
23 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.47510534 |
24 | Thyroid carcinoma (HP:0002890) | 2.45657269 |
25 | Eczematoid dermatitis (HP:0000976) | 2.44740912 |
26 | Abnormality of the common coagulation pathway (HP:0010990) | 2.40458397 |
27 | Meningitis (HP:0001287) | 2.40418835 |
28 | Arterial tortuosity (HP:0005116) | 2.39596022 |
29 | Complement deficiency (HP:0004431) | 2.35522883 |
30 | Curly hair (HP:0002212) | 2.34215301 |
31 | Mitral stenosis (HP:0001718) | 2.31624547 |
32 | Pulmonary embolism (HP:0002204) | 2.28184080 |
33 | Dilatation of the ascending aorta (HP:0005111) | 2.28032755 |
34 | Spondylolisthesis (HP:0003302) | 2.27918930 |
35 | Dysostosis multiplex (HP:0000943) | 2.26591952 |
36 | Absent frontal sinuses (HP:0002688) | 2.24757864 |
37 | Epidermoid cyst (HP:0200040) | 2.24341806 |
38 | Osteolytic defects of the hand bones (HP:0009699) | 2.23860470 |
39 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.23860470 |
40 | Leukocytosis (HP:0001974) | 2.22873431 |
41 | Thick nail (HP:0001805) | 2.22635296 |
42 | Aortic dissection (HP:0002647) | 2.20185343 |
43 | Vascular tortuosity (HP:0004948) | 2.17849223 |
44 | Encephalitis (HP:0002383) | 2.17151439 |
45 | Fair hair (HP:0002286) | 2.15874751 |
46 | Persistence of primary teeth (HP:0006335) | 2.15698723 |
47 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.15650118 |
48 | Abnormality of the fingertips (HP:0001211) | 2.15240528 |
49 | Mucopolysacchariduria (HP:0008155) | 2.14216444 |
50 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.14216444 |
51 | Viral hepatitis (HP:0006562) | 2.13614257 |
52 | Prolonged bleeding time (HP:0003010) | 2.11244888 |
53 | Deep venous thrombosis (HP:0002625) | 2.11208373 |
54 | Episodic fever (HP:0001954) | 2.10607381 |
55 | Osteomyelitis (HP:0002754) | 2.10557066 |
56 | Amyloidosis (HP:0011034) | 2.09830202 |
57 | Hypoglycemic seizures (HP:0002173) | 2.08932018 |
58 | Systemic lupus erythematosus (HP:0002725) | 2.07693609 |
59 | Urticaria (HP:0001025) | 2.06466473 |
60 | Abnormality of T cells (HP:0002843) | 2.06364194 |
61 | Recurrent bronchitis (HP:0002837) | 2.05290781 |
62 | Generalized hypopigmentation of hair (HP:0011358) | 2.05254197 |
63 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.03970456 |
64 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.03970456 |
65 | Abnormality of glycolipid metabolism (HP:0010969) | 2.03970456 |
66 | Increased CSF protein (HP:0002922) | 2.02549992 |
67 | Conjugated hyperbilirubinemia (HP:0002908) | 2.02172900 |
68 | Thickened calvaria (HP:0002684) | 2.01661152 |
69 | Menstrual irregularities (HP:0000858) | 2.01497893 |
70 | Coarse hair (HP:0002208) | 2.01446009 |
71 | Periodontitis (HP:0000704) | 2.00978566 |
72 | Gangrene (HP:0100758) | 2.00950677 |
73 | Abnormality of complement system (HP:0005339) | 2.00451880 |
74 | Acute myeloid leukemia (HP:0004808) | 2.00341759 |
75 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.99505022 |
76 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.99505022 |
77 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.99505022 |
78 | Autoimmune hemolytic anemia (HP:0001890) | 1.96076909 |
79 | Arterial thrombosis (HP:0004420) | 1.94505670 |
80 | Epistaxis (HP:0000421) | 1.94450963 |
81 | Abnormality of proline metabolism (HP:0010907) | 1.94412922 |
82 | Hydroxyprolinuria (HP:0003080) | 1.94412922 |
83 | Intrahepatic cholestasis (HP:0001406) | 1.94391628 |
84 | T lymphocytopenia (HP:0005403) | 1.94332937 |
85 | Widely spaced teeth (HP:0000687) | 1.93546496 |
86 | Chronic diarrhea (HP:0002028) | 1.90299000 |
87 | Abnormality of T cell number (HP:0011839) | 1.89848183 |
88 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.89201341 |
89 | Spinal cord lesions (HP:0100561) | 1.86321604 |
90 | Syringomyelia (HP:0003396) | 1.86321604 |
91 | Obstructive lung disease (HP:0006536) | 1.86260170 |
92 | Chronic obstructive pulmonary disease (HP:0006510) | 1.86260170 |
93 | Neonatal hypoglycemia (HP:0001998) | 1.85459174 |
94 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.85023713 |
95 | Slow saccadic eye movements (HP:0000514) | 1.84090871 |
96 | Striae distensae (HP:0001065) | 1.83527048 |
97 | Hypoalphalipoproteinemia (HP:0003233) | 1.83438506 |
98 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.82857284 |
99 | Pustule (HP:0200039) | 1.82374116 |
100 | Inflammation of the large intestine (HP:0002037) | 1.80823282 |
101 | Aneurysm (HP:0002617) | 1.80568908 |
102 | Eosinophilia (HP:0001880) | 1.78935726 |
103 | Anorexia (HP:0002039) | 1.78377022 |
104 | Inappropriate behavior (HP:0000719) | 1.78258927 |
105 | Thyroiditis (HP:0100646) | 1.77674689 |
106 | Gastrointestinal infarctions (HP:0005244) | 1.77332994 |
107 | Increased IgE level (HP:0003212) | 1.77174734 |
108 | Acute hepatic failure (HP:0006554) | 1.77127854 |
109 | Testicular neoplasm (HP:0010788) | 1.77105752 |
110 | Skin nodule (HP:0200036) | 1.76784295 |
111 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.76441914 |
112 | Cellulitis (HP:0100658) | 1.76270270 |
113 | Hypochromic microcytic anemia (HP:0004840) | 1.75705623 |
114 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.75456732 |
115 | Bladder carcinoma (HP:0002862) | 1.74711410 |
116 | Bladder neoplasm (HP:0009725) | 1.74711410 |
117 | Gingival bleeding (HP:0000225) | 1.74567649 |
118 | Narrow palate (HP:0000189) | 1.73899203 |
119 | Nephritis (HP:0000123) | 1.73822637 |
120 | Truncal obesity (HP:0001956) | 1.73542843 |
121 | Hyperglycemia (HP:0003074) | 1.72201370 |
122 | Hypercholesterolemia (HP:0003124) | 1.72142879 |
123 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.72033797 |
124 | Cubitus valgus (HP:0002967) | 1.71902693 |
125 | Rectal prolapse (HP:0002035) | 1.71718022 |
126 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.70882563 |
127 | Symptomatic seizures (HP:0011145) | 1.70007178 |
128 | Abnormality of the endocardium (HP:0004306) | 1.67794524 |
129 | Recurrent fungal infections (HP:0002841) | 1.66658322 |
130 | Alveolar cell carcinoma (HP:0006519) | 1.66425838 |
131 | Hepatocellular carcinoma (HP:0001402) | 1.65920246 |
132 | Esophageal varix (HP:0002040) | 1.65155315 |
133 | Abnormality of the axillary hair (HP:0100134) | 1.64858330 |
134 | Abnormality of the frontal sinuses (HP:0002687) | 1.64381451 |
135 | Disinhibition (HP:0000734) | 1.63957577 |
136 | Increased density of long bones (HP:0006392) | 1.63769456 |
137 | Myositis (HP:0100614) | 1.61574444 |
138 | Papilledema (HP:0001085) | 1.61149618 |
139 | Glomerulonephritis (HP:0000099) | 1.59609463 |
140 | Recurrent bacterial skin infections (HP:0005406) | 1.59236824 |
141 | Orchitis (HP:0100796) | 1.58900561 |
142 | Retinal atrophy (HP:0001105) | 1.58712588 |
143 | Optic neuritis (HP:0100653) | 1.57823504 |
144 | Retrobulbar optic neuritis (HP:0100654) | 1.57823504 |
145 | Spontaneous hematomas (HP:0007420) | 1.56955525 |
146 | Abnormality of the intrinsic pathway (HP:0010989) | 1.56177695 |
147 | Increased mean platelet volume (HP:0011877) | 1.55651909 |
148 | Atrophic scars (HP:0001075) | 1.53715191 |
149 | Tibial bowing (HP:0002982) | 1.53517683 |
150 | Autoimmune thrombocytopenia (HP:0001973) | 1.52780944 |
151 | Abdominal distention (HP:0003270) | 1.52393344 |
152 | Joint hemorrhage (HP:0005261) | 1.51900681 |
153 | Broad ribs (HP:0000885) | 1.51511388 |
154 | Abnormal platelet volume (HP:0011876) | 1.51277583 |
155 | Peritonitis (HP:0002586) | 1.51243126 |
156 | Shallow orbits (HP:0000586) | 1.51164632 |
157 | Gingivitis (HP:0000230) | 1.50782883 |
158 | Disproportionate tall stature (HP:0001519) | 1.50728006 |
159 | Vasculitis (HP:0002633) | 1.49869814 |
160 | Submucous cleft hard palate (HP:0000176) | 1.49393403 |
161 | Recurrent viral infections (HP:0004429) | 1.48853766 |
162 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.48821348 |
163 | Abnormality of the nasal septum (HP:0000419) | 1.48302226 |
164 | Hemorrhage of the eye (HP:0011885) | 1.48085305 |
165 | Abnormal foot bone ossification (HP:0010675) | 1.47958097 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 3.56002894 |
2 | BLK | 2.55285569 |
3 | TAOK3 | 2.16325116 |
4 | JAK1 | 2.03574128 |
5 | BMPR2 | 1.99560533 |
6 | NUAK1 | 1.97068090 |
7 | MAP3K14 | 1.92204063 |
8 | FGFR3 | 1.91837675 |
9 | SIK1 | 1.85364982 |
10 | EPHB1 | 1.84444560 |
11 | RIPK1 | 1.79959888 |
12 | ACVR1B | 1.78477654 |
13 | CAMK1D | 1.78449500 |
14 | MAP2K3 | 1.77825835 |
15 | INSRR | 1.76358910 |
16 | MAP3K10 | 1.75814168 |
17 | TGFBR2 | 1.74442820 |
18 | JAK3 | 1.68548514 |
19 | YES1 | 1.68138391 |
20 | AKT3 | 1.63434660 |
21 | FGFR4 | 1.61130259 |
22 | LATS1 | 1.57601776 |
23 | EPHA3 | 1.57123818 |
24 | CAMK1G | 1.56314619 |
25 | PTK6 | 1.54030355 |
26 | TYK2 | 1.50664517 |
27 | GRK6 | 1.46780658 |
28 | FGFR2 | 1.44076483 |
29 | PDGFRB | 1.43507005 |
30 | SCYL2 | 1.40325459 |
31 | IRAK2 | 1.37528532 |
32 | ITK | 1.33768901 |
33 | TRIB3 | 1.33077256 |
34 | MAPK15 | 1.30763583 |
35 | BTK | 1.28249974 |
36 | PRPF4B | 1.24747666 |
37 | MAP3K1 | 1.24481539 |
38 | ZAP70 | 1.24107631 |
39 | ERN1 | 1.21676682 |
40 | SGK3 | 1.21473920 |
41 | TEC | 1.21217821 |
42 | SYK | 1.20423666 |
43 | CAMKK2 | 1.20054242 |
44 | MAP3K13 | 1.19305422 |
45 | CSK | 1.16210215 |
46 | HIPK2 | 1.15321343 |
47 | CSF1R | 1.14952035 |
48 | STK24 | 1.11860871 |
49 | PDGFRA | 1.07986010 |
50 | MAP4K1 | 1.07640647 |
51 | RET | 1.07536306 |
52 | JAK2 | 1.06455504 |
53 | TXK | 1.06439832 |
54 | TTN | 1.06266487 |
55 | KSR1 | 1.04454879 |
56 | TBK1 | 1.02607290 |
57 | MAP3K6 | 1.01642832 |
58 | PRKCH | 1.01282976 |
59 | CDK6 | 0.98541335 |
60 | PIK3CA | 0.98473730 |
61 | IKBKE | 0.97898917 |
62 | BRD4 | 0.97605281 |
63 | MAPK7 | 0.96072998 |
64 | SGK2 | 0.95474815 |
65 | LYN | 0.95266695 |
66 | KSR2 | 0.92139978 |
67 | PTK2 | 0.91957286 |
68 | HCK | 0.88556136 |
69 | IRAK3 | 0.88483758 |
70 | MARK3 | 0.84530552 |
71 | STK10 | 0.83667630 |
72 | IKBKB | 0.82635513 |
73 | CHUK | 0.79446810 |
74 | CDK12 | 0.79251421 |
75 | MAP3K7 | 0.78597150 |
76 | FES | 0.78478439 |
77 | SIK3 | 0.78346599 |
78 | PTK2B | 0.77787155 |
79 | PRKCQ | 0.74921287 |
80 | TAOK1 | 0.72097257 |
81 | FLT3 | 0.71692196 |
82 | KIT | 0.70617112 |
83 | DDR2 | 0.70365634 |
84 | MAP2K4 | 0.70213951 |
85 | MARK2 | 0.69984996 |
86 | STK3 | 0.69117245 |
87 | DMPK | 0.68915982 |
88 | PAK3 | 0.68842085 |
89 | LCK | 0.68641324 |
90 | ERBB3 | 0.68566041 |
91 | MELK | 0.68085142 |
92 | TRPM7 | 0.68018718 |
93 | IRAK4 | 0.67764415 |
94 | PDK1 | 0.67032881 |
95 | PRKAA2 | 0.65691658 |
96 | LRRK2 | 0.65491198 |
97 | NEK6 | 0.65345816 |
98 | IRAK1 | 0.65096284 |
99 | MST1R | 0.64539380 |
100 | INSR | 0.63229879 |
101 | DYRK1B | 0.63224013 |
102 | NLK | 0.63116264 |
103 | GSK3A | 0.62924119 |
104 | STK11 | 0.62719172 |
105 | FGR | 0.62473406 |
106 | FER | 0.61959972 |
107 | PIK3CG | 0.60442806 |
108 | EIF2AK3 | 0.60289860 |
109 | TNK2 | 0.60119915 |
110 | PDPK1 | 0.59701992 |
111 | MAP3K3 | 0.59272771 |
112 | MAP3K4 | 0.58921340 |
113 | IGF1R | 0.57688566 |
114 | * MAP3K2 | 0.57285853 |
115 | CDK9 | 0.56972033 |
116 | BMX | 0.56155153 |
117 | SGK223 | 0.54952474 |
118 | SGK494 | 0.54952474 |
119 | CAMKK1 | 0.54760625 |
120 | MAP3K5 | 0.54187173 |
121 | MST4 | 0.53601054 |
122 | RAF1 | 0.53574780 |
123 | OXSR1 | 0.53427014 |
124 | NEK9 | 0.53208594 |
125 | STK38L | 0.52899126 |
126 | WNK1 | 0.52605142 |
127 | SIK2 | 0.52286399 |
128 | PKN2 | 0.52037688 |
129 | FYN | 0.51600882 |
130 | RPS6KA2 | 0.51345941 |
131 | RIPK4 | 0.48961366 |
132 | MATK | 0.48090380 |
133 | MAP3K9 | 0.47531074 |
134 | SGK1 | 0.47143120 |
135 | RPS6KB1 | 0.47129805 |
136 | EGFR | 0.47124517 |
137 | PIM1 | 0.46259347 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.72630177 |
2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.60472054 |
3 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.51457642 |
4 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.50881064 |
5 | Legionellosis_Homo sapiens_hsa05134 | 1.47085598 |
6 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.36514301 |
7 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.35623109 |
8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.35432737 |
9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.31094095 |
10 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.30599773 |
11 | Influenza A_Homo sapiens_hsa05164 | 1.25021309 |
12 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.24384416 |
13 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.22818335 |
14 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.22037756 |
15 | Allograft rejection_Homo sapiens_hsa05330 | 1.19800207 |
16 | Leishmaniasis_Homo sapiens_hsa05140 | 1.17297242 |
17 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.15528783 |
18 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.15482542 |
19 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.14432602 |
20 | Insulin resistance_Homo sapiens_hsa04931 | 1.13703128 |
21 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.13308428 |
22 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.12755023 |
23 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.10840238 |
24 | ABC transporters_Homo sapiens_hsa02010 | 1.10094681 |
25 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.06287452 |
26 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.06231514 |
27 | Lysine degradation_Homo sapiens_hsa00310 | 1.01651249 |
28 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.01536955 |
29 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.01415131 |
30 | Phagosome_Homo sapiens_hsa04145 | 1.00867998 |
31 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.99537909 |
32 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.98711891 |
33 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.98064672 |
34 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.97832363 |
35 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.97432450 |
36 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.96138759 |
37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.93809185 |
38 | Focal adhesion_Homo sapiens_hsa04510 | 0.93743793 |
39 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.93216121 |
40 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.92693805 |
41 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.92422859 |
42 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.91766081 |
43 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.90068020 |
44 | Other glycan degradation_Homo sapiens_hsa00511 | 0.89578292 |
45 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.89349858 |
46 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.88888716 |
47 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.86767975 |
48 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.86607807 |
49 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.85535402 |
50 | Amoebiasis_Homo sapiens_hsa05146 | 0.84982037 |
51 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.84310409 |
52 | Platelet activation_Homo sapiens_hsa04611 | 0.83784312 |
53 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.82029681 |
54 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.81510567 |
55 | Lysosome_Homo sapiens_hsa04142 | 0.81165018 |
56 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.80422502 |
57 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.79051192 |
58 | Bile secretion_Homo sapiens_hsa04976 | 0.78358311 |
59 | Malaria_Homo sapiens_hsa05144 | 0.77360578 |
60 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.77236722 |
61 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.76659548 |
62 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.76387373 |
63 | Asthma_Homo sapiens_hsa05310 | 0.76048588 |
64 | Tuberculosis_Homo sapiens_hsa05152 | 0.75947211 |
65 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.75441719 |
66 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.74643445 |
67 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.74263856 |
68 | Measles_Homo sapiens_hsa05162 | 0.73731414 |
69 | Pertussis_Homo sapiens_hsa05133 | 0.73574418 |
70 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.73550559 |
71 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.73134998 |
72 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.73108336 |
73 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.72868123 |
74 | Endometrial cancer_Homo sapiens_hsa05213 | 0.72808021 |
75 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.72610070 |
76 | Prostate cancer_Homo sapiens_hsa05215 | 0.72436360 |
77 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.71419620 |
78 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.71295955 |
79 | Adherens junction_Homo sapiens_hsa04520 | 0.70520120 |
80 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.69833990 |
81 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.68765148 |
82 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.68362418 |
83 | Renin secretion_Homo sapiens_hsa04924 | 0.67675408 |
84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.66513934 |
85 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.66507258 |
86 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.66481767 |
87 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.66433365 |
88 | Prion diseases_Homo sapiens_hsa05020 | 0.66280192 |
89 | Hepatitis C_Homo sapiens_hsa05160 | 0.66070366 |
90 | Glioma_Homo sapiens_hsa05214 | 0.65922800 |
91 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.64847948 |
92 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.64726870 |
93 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.63694684 |
94 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.62824626 |
95 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.62338082 |
96 | Circadian rhythm_Homo sapiens_hsa04710 | 0.61795347 |
97 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.61329333 |
98 | Salmonella infection_Homo sapiens_hsa05132 | 0.61009075 |
99 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.59906278 |
100 | Apoptosis_Homo sapiens_hsa04210 | 0.59473469 |
101 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.59296455 |
102 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.58581895 |
103 | Hepatitis B_Homo sapiens_hsa05161 | 0.57905964 |
104 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.57025492 |
105 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.56804632 |
106 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.56636971 |
107 | * GnRH signaling pathway_Homo sapiens_hsa04912 | 0.56278891 |
108 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.55717314 |
109 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.55432072 |
110 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55407912 |
111 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.54730457 |
112 | Colorectal cancer_Homo sapiens_hsa05210 | 0.54182130 |
113 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.54085943 |
114 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.53608180 |
115 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.53539526 |
116 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.53241747 |
117 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.51906587 |
118 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.51503829 |
119 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.51329148 |
120 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.51002395 |
121 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.50326322 |
122 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.50101603 |
123 | Thyroid cancer_Homo sapiens_hsa05216 | 0.49948260 |
124 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.49469471 |
125 | Viral myocarditis_Homo sapiens_hsa05416 | 0.49264631 |
126 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.49225157 |
127 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.49132197 |
128 | Endocytosis_Homo sapiens_hsa04144 | 0.48918913 |
129 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.48579811 |
130 | Long-term potentiation_Homo sapiens_hsa04720 | 0.48118088 |
131 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.48086089 |
132 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.47686853 |