Rank | Gene Set | Z-score |
---|---|---|
1 | plasma membrane repair (GO:0001778) | 4.52867223 |
2 | synaptic vesicle maturation (GO:0016188) | 3.95975357 |
3 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.88040466 |
4 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.86564814 |
5 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.66109364 |
6 | axon ensheathment in central nervous system (GO:0032291) | 3.63058230 |
7 | central nervous system myelination (GO:0022010) | 3.63058230 |
8 | sarcomere organization (GO:0045214) | 3.58774228 |
9 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.49910526 |
10 | cardiac myofibril assembly (GO:0055003) | 3.46979591 |
11 | regulation of synapse structural plasticity (GO:0051823) | 3.45101852 |
12 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.43976013 |
13 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.42460839 |
14 | locomotory exploration behavior (GO:0035641) | 3.33623264 |
15 | cell communication by electrical coupling (GO:0010644) | 3.30962564 |
16 | barbed-end actin filament capping (GO:0051016) | 3.29115830 |
17 | regulation of early endosome to late endosome transport (GO:2000641) | 3.27424547 |
18 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 3.26902247 |
19 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 3.25556787 |
20 | layer formation in cerebral cortex (GO:0021819) | 3.22888784 |
21 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.21008580 |
22 | sodium ion export (GO:0071436) | 3.17303889 |
23 | myofibril assembly (GO:0030239) | 3.16090349 |
24 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.09261914 |
25 | protein localization to endosome (GO:0036010) | 3.07675091 |
26 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.07290275 |
27 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 3.07036956 |
28 | negative regulation of protein localization to cell surface (GO:2000009) | 3.06637557 |
29 | cell-substrate junction assembly (GO:0007044) | 3.00031405 |
30 | cell-substrate adherens junction assembly (GO:0007045) | 2.94806435 |
31 | focal adhesion assembly (GO:0048041) | 2.94806435 |
32 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 2.94389211 |
33 | actin-myosin filament sliding (GO:0033275) | 2.94179641 |
34 | muscle filament sliding (GO:0030049) | 2.94179641 |
35 | adherens junction assembly (GO:0034333) | 2.93948722 |
36 | cell communication involved in cardiac conduction (GO:0086065) | 2.92285171 |
37 | dendritic spine morphogenesis (GO:0060997) | 2.89461997 |
38 | cardiac muscle contraction (GO:0060048) | 2.89390336 |
39 | potassium ion import (GO:0010107) | 2.88871224 |
40 | regulation of membrane repolarization (GO:0060306) | 2.88797724 |
41 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.82937008 |
42 | activation of protein kinase A activity (GO:0034199) | 2.82532435 |
43 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.81849152 |
44 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.81573624 |
45 | positive regulation of myotube differentiation (GO:0010831) | 2.81369400 |
46 | vocalization behavior (GO:0071625) | 2.80515346 |
47 | synaptic vesicle exocytosis (GO:0016079) | 2.78874282 |
48 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.78132469 |
49 | stress fiber assembly (GO:0043149) | 2.77899124 |
50 | cell-cell junction maintenance (GO:0045217) | 2.77834962 |
51 | neuronal action potential propagation (GO:0019227) | 2.76567019 |
52 | cellular response to epinephrine stimulus (GO:0071872) | 2.76194217 |
53 | glutamate secretion (GO:0014047) | 2.76098764 |
54 | cellular response to monoamine stimulus (GO:0071868) | 2.76008803 |
55 | cellular response to catecholamine stimulus (GO:0071870) | 2.76008803 |
56 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.75327842 |
57 | regulation of calcium ion transmembrane transport (GO:1903169) | 2.74975801 |
58 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 2.74975801 |
59 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.74476264 |
60 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.74305389 |
61 | regulation of cell communication by electrical coupling (GO:0010649) | 2.72340730 |
62 | dendrite morphogenesis (GO:0048813) | 2.72071381 |
63 | hemidesmosome assembly (GO:0031581) | 2.71794306 |
64 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.71113104 |
65 | ensheathment of neurons (GO:0007272) | 2.70544642 |
66 | axon ensheathment (GO:0008366) | 2.70544642 |
67 | cellular potassium ion homeostasis (GO:0030007) | 2.70108276 |
68 | cortical actin cytoskeleton organization (GO:0030866) | 2.69843736 |
69 | membrane tubulation (GO:0097320) | 2.68199046 |
70 | positive regulation of protein dephosphorylation (GO:0035307) | 2.67819531 |
71 | activation of MAPKKK activity (GO:0000185) | 2.67609211 |
72 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.66958686 |
73 | myelination (GO:0042552) | 2.66931577 |
74 | establishment of nucleus localization (GO:0040023) | 2.66646788 |
75 | regulation of actin filament-based movement (GO:1903115) | 2.66123051 |
76 | actomyosin structure organization (GO:0031032) | 2.65910406 |
77 | creatine metabolic process (GO:0006600) | 2.65683843 |
78 | positive regulation of receptor recycling (GO:0001921) | 2.63099668 |
79 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 2.56957891 |
80 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.56516205 |
81 | neuromuscular process controlling balance (GO:0050885) | 2.53430927 |
82 | cerebellar Purkinje cell layer development (GO:0021680) | 2.53359464 |
83 | glycine transport (GO:0015816) | 2.53358342 |
84 | neuronal ion channel clustering (GO:0045161) | 2.50980314 |
85 | cell migration in hindbrain (GO:0021535) | 2.50885151 |
86 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.50437971 |
87 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.49849019 |
88 | neuron recognition (GO:0008038) | 2.49633049 |
89 | nerve growth factor signaling pathway (GO:0038180) | 2.49353710 |
90 | regulation of ARF GTPase activity (GO:0032312) | 2.48504805 |
91 | neuromuscular junction development (GO:0007528) | 2.48381934 |
92 | signal complex assembly (GO:0007172) | 2.46734513 |
93 | adenosine receptor signaling pathway (GO:0001973) | 2.46535694 |
94 | protein targeting to plasma membrane (GO:0072661) | 2.45723116 |
95 | axonal fasciculation (GO:0007413) | 2.44503054 |
96 | mannose metabolic process (GO:0006013) | 2.44130828 |
97 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.43688487 |
98 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.43453134 |
99 | regulation of ARF protein signal transduction (GO:0032012) | 2.43377202 |
100 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.41853405 |
101 | establishment of mitochondrion localization (GO:0051654) | 2.41680763 |
102 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.41037437 |
103 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.40640482 |
104 | striated muscle contraction (GO:0006941) | 2.39791781 |
105 | skin morphogenesis (GO:0043589) | 2.39142077 |
106 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 2.38049127 |
107 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.37348399 |
108 | peripheral nervous system axon ensheathment (GO:0032292) | 2.36977256 |
109 | myelination in peripheral nervous system (GO:0022011) | 2.36977256 |
110 | cell migration involved in heart development (GO:0060973) | 2.36781230 |
111 | L-amino acid import (GO:0043092) | 2.36718665 |
112 | actin-mediated cell contraction (GO:0070252) | 2.36611015 |
113 | negative regulation of cell killing (GO:0031342) | 2.35344195 |
114 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.35344195 |
115 | cortical cytoskeleton organization (GO:0030865) | 2.33304989 |
116 | positive regulation of potassium ion transport (GO:0043268) | 2.32858282 |
117 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.32805048 |
118 | negative regulation of cell size (GO:0045792) | 2.31032653 |
119 | response to muramyl dipeptide (GO:0032495) | 2.30417163 |
120 | dopamine receptor signaling pathway (GO:0007212) | 2.30108767 |
121 | regulation of striated muscle contraction (GO:0006942) | 2.30015025 |
122 | negative regulation of potassium ion transport (GO:0043267) | 2.29120447 |
123 | response to laminar fluid shear stress (GO:0034616) | 2.28707869 |
124 | positive regulation of axon extension (GO:0045773) | 2.28661692 |
125 | semaphorin-plexin signaling pathway (GO:0071526) | 2.28074533 |
126 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.27498804 |
127 | virion attachment to host cell (GO:0019062) | 2.26975566 |
128 | adhesion of symbiont to host cell (GO:0044650) | 2.26975566 |
129 | exploration behavior (GO:0035640) | 2.26795091 |
130 | actin filament-based movement (GO:0030048) | 2.26781460 |
131 | membrane depolarization during action potential (GO:0086010) | 2.26189735 |
132 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.25763952 |
133 | regulation of synaptic vesicle transport (GO:1902803) | 2.25703475 |
134 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.25700723 |
135 | cerebellar granule cell differentiation (GO:0021707) | 2.24979723 |
136 | regulation of skeletal muscle contraction (GO:0014819) | 2.24405894 |
137 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.24369506 |
138 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.23687597 |
139 | regulation of cation channel activity (GO:2001257) | 2.23113015 |
140 | modulation by symbiont of host cellular process (GO:0044068) | 2.22993527 |
141 | potassium ion homeostasis (GO:0055075) | 2.22813417 |
142 | positive regulation of synapse maturation (GO:0090129) | 2.21963275 |
143 | positive regulation of Rap GTPase activity (GO:0032854) | 2.18101089 |
144 | positive regulation of fibroblast migration (GO:0010763) | 2.17493699 |
145 | substrate-dependent cell migration (GO:0006929) | 2.17122156 |
146 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.16611052 |
147 | response to monoamine (GO:0071867) | 2.15658086 |
148 | response to catecholamine (GO:0071869) | 2.15658086 |
149 | endodermal cell differentiation (GO:0035987) | 2.14497131 |
150 | axon extension (GO:0048675) | 2.14004324 |
151 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.13131227 |
152 | negative regulation of Ras protein signal transduction (GO:0046580) | 2.12703799 |
153 | regulation of macrophage cytokine production (GO:0010935) | 2.12125223 |
154 | apoptotic process involved in morphogenesis (GO:0060561) | 2.10381470 |
155 | response to parathyroid hormone (GO:0071107) | 2.10022706 |
156 | venous blood vessel morphogenesis (GO:0048845) | 2.09298427 |
157 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.09257360 |
158 | cell junction maintenance (GO:0034331) | 2.08150372 |
159 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.07809507 |
160 | adhesion of symbiont to host (GO:0044406) | 2.06526160 |
161 | modulation by symbiont of host immune response (GO:0052553) | 2.05103078 |
162 | modulation by symbiont of host defense response (GO:0052031) | 2.05103078 |
163 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.05103078 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.50451430 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.12305823 |
3 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.51491346 |
4 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.44274356 |
5 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.44274356 |
6 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.38968515 |
7 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.32680941 |
8 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.25779806 |
9 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.22577527 |
10 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.19058328 |
11 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.15544979 |
12 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.14093845 |
13 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.13634763 |
14 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.07814991 |
15 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.07730722 |
16 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.03919796 |
17 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.00538926 |
18 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.99696617 |
19 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.98011035 |
20 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.97485416 |
21 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.95041229 |
22 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.93375377 |
23 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.91782969 |
24 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.87292404 |
25 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.85332479 |
26 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.81926409 |
27 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.81162703 |
28 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.78945823 |
29 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.77275658 |
30 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.77048347 |
31 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.76513816 |
32 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.76228772 |
33 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.73884787 |
34 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.71077938 |
35 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.68847228 |
36 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.68516920 |
37 | MYC_22102868_ChIP-Seq_BL_Human | 1.67121760 |
38 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.64773399 |
39 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.61382417 |
40 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.54945226 |
41 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.52130611 |
42 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.52071379 |
43 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.51874727 |
44 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.50817397 |
45 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.49079150 |
46 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.48866574 |
47 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.46454129 |
48 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.45041927 |
49 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.43679580 |
50 | * LXR_22292898_ChIP-Seq_THP-1_Human | 1.42339379 |
51 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.41658642 |
52 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.41372319 |
53 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.40944024 |
54 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.36406844 |
55 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.36065906 |
56 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.35039151 |
57 | P68_20966046_ChIP-Seq_HELA_Human | 1.34568246 |
58 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.33079260 |
59 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.31880170 |
60 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.31185472 |
61 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.31185472 |
62 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.29479807 |
63 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.28586688 |
64 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.25843003 |
65 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.25783904 |
66 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.25621669 |
67 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.24509384 |
68 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.23999287 |
69 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.22984332 |
70 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.22443834 |
71 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.21660671 |
72 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.21437149 |
73 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.19493663 |
74 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.19146087 |
75 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.17872106 |
76 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.17575173 |
77 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.16560935 |
78 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.15569674 |
79 | * MAF_26560356_Chip-Seq_TH1_Human | 1.15019323 |
80 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.14955986 |
81 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.12419754 |
82 | * CTCF_27219007_Chip-Seq_Bcells_Human | 1.12236754 |
83 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.12174432 |
84 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.12083765 |
85 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.11947341 |
86 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.11241667 |
87 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.09772885 |
88 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.09642105 |
89 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.09085381 |
90 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.07900864 |
91 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.07851546 |
92 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.07447483 |
93 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.07184778 |
94 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.07173811 |
95 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.07146102 |
96 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06240819 |
97 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.06194265 |
98 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.05989712 |
99 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.05711960 |
100 | * SPI1_23127762_ChIP-Seq_K562_Human | 1.05486264 |
101 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.05480950 |
102 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.05273106 |
103 | MAF_26560356_Chip-Seq_TH2_Human | 1.03738450 |
104 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.03003545 |
105 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.02066399 |
106 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.01622841 |
107 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.01238698 |
108 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.00977325 |
109 | * ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.00736879 |
110 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.00168157 |
111 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.99788706 |
112 | * TP63_22573176_ChIP-Seq_HFKS_Human | 0.98691749 |
113 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.98372465 |
114 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98194342 |
115 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.97693170 |
116 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.97397998 |
117 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.94857646 |
118 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.92935476 |
119 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.91047736 |
120 | AR_19668381_ChIP-Seq_PC3_Human | 0.90458785 |
121 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.90101869 |
122 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.89939876 |
123 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.89295567 |
124 | TP53_16413492_ChIP-PET_HCT116_Human | 0.89183397 |
125 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.88836251 |
126 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.88795212 |
127 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.88652401 |
128 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.87885690 |
129 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.86769471 |
130 | GATA1_19941826_ChIP-Seq_K562_Human | 0.86450875 |
131 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.86210552 |
132 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.85443346 |
133 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.84951403 |
134 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.84653513 |
135 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.84159581 |
136 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.83363350 |
137 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.83192319 |
138 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.82704797 |
139 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.82479585 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 4.27690494 |
2 | MP0000751_myopathy | 3.81367713 |
3 | MP0002837_dystrophic_cardiac_calcinosis | 3.39269884 |
4 | MP0004270_analgesia | 2.65821859 |
5 | MP0004084_abnormal_cardiac_muscle | 2.62121227 |
6 | MP0000749_muscle_degeneration | 2.57290294 |
7 | MP0003880_abnormal_central_pattern | 2.40546668 |
8 | MP0004145_abnormal_muscle_electrophysio | 2.39921137 |
9 | MP0003635_abnormal_synaptic_transmissio | 2.33356285 |
10 | MP0005623_abnormal_meninges_morphology | 2.32358254 |
11 | MP0004036_abnormal_muscle_relaxation | 2.25944819 |
12 | MP0005451_abnormal_body_composition | 2.25412369 |
13 | MP0003828_pulmonary_edema | 2.15795752 |
14 | MP0008438_abnormal_cutaneous_collagen | 2.13366547 |
15 | MP0003646_muscle_fatigue | 2.10028848 |
16 | MP0004087_abnormal_muscle_fiber | 2.09526196 |
17 | MP0000747_muscle_weakness | 2.07352177 |
18 | MP0009840_abnormal_foam_cell | 2.06985683 |
19 | MP0003329_amyloid_beta_deposits | 2.03687277 |
20 | MP0004215_abnormal_myocardial_fiber | 1.98949490 |
21 | MP0004858_abnormal_nervous_system | 1.98358553 |
22 | MP0005058_abnormal_lysosome_morphology | 1.96959178 |
23 | MP0003300_gastrointestinal_ulcer | 1.94461648 |
24 | MP0000920_abnormal_myelination | 1.94326265 |
25 | MP0003436_decreased_susceptibility_to | 1.91786460 |
26 | MP0005330_cardiomyopathy | 1.89636835 |
27 | MP0002064_seizures | 1.82950462 |
28 | MP0003137_abnormal_impulse_conducting | 1.78112224 |
29 | MP0004510_myositis | 1.76905444 |
30 | MP0000750_abnormal_muscle_regeneration | 1.74210706 |
31 | MP0001849_ear_inflammation | 1.72435312 |
32 | MP0002063_abnormal_learning/memory/cond | 1.68478544 |
33 | MP0000759_abnormal_skeletal_muscle | 1.67873981 |
34 | MP0002106_abnormal_muscle_physiology | 1.66078258 |
35 | MP0005409_darkened_coat_color | 1.64646555 |
36 | MP0009780_abnormal_chondrocyte_physiolo | 1.64506232 |
37 | MP0004130_abnormal_muscle_cell | 1.62868841 |
38 | MP0003705_abnormal_hypodermis_morpholog | 1.62824446 |
39 | MP0005620_abnormal_muscle_contractility | 1.61345722 |
40 | MP0002972_abnormal_cardiac_muscle | 1.61234062 |
41 | MP0009745_abnormal_behavioral_response | 1.59844204 |
42 | MP0002877_abnormal_melanocyte_morpholog | 1.59786793 |
43 | MP0009046_muscle_twitch | 1.59486409 |
44 | MP0008569_lethality_at_weaning | 1.57006823 |
45 | MP0003172_abnormal_lysosome_physiology | 1.53387942 |
46 | MP0009278_abnormal_bone_marrow | 1.52275400 |
47 | MP0008260_abnormal_autophagy | 1.50911986 |
48 | MP0005369_muscle_phenotype | 1.46335624 |
49 | MP0002272_abnormal_nervous_system | 1.46333750 |
50 | MP0003191_abnormal_cellular_cholesterol | 1.46202351 |
51 | MP0002269_muscular_atrophy | 1.46008120 |
52 | MP0005423_abnormal_somatic_nervous | 1.44688344 |
53 | MP0000343_altered_response_to | 1.43779636 |
54 | MP0004085_abnormal_heartbeat | 1.42708907 |
55 | MP0003690_abnormal_glial_cell | 1.40887647 |
56 | MP0004233_abnormal_muscle_weight | 1.40597085 |
57 | MP0000013_abnormal_adipose_tissue | 1.38485168 |
58 | MP0004484_altered_response_of | 1.37404168 |
59 | MP0001299_abnormal_eye_distance/ | 1.34606142 |
60 | MP0002909_abnormal_adrenal_gland | 1.33941799 |
61 | MP0006138_congestive_heart_failure | 1.32498444 |
62 | MP0000778_abnormal_nervous_system | 1.32248845 |
63 | MP0003634_abnormal_glial_cell | 1.31880764 |
64 | MP0003453_abnormal_keratinocyte_physiol | 1.30422983 |
65 | MP0008775_abnormal_heart_ventricle | 1.30156359 |
66 | MP0003279_aneurysm | 1.29627743 |
67 | MP0010630_abnormal_cardiac_muscle | 1.29467171 |
68 | MP0002734_abnormal_mechanical_nocicepti | 1.28718895 |
69 | MP0003879_abnormal_hair_cell | 1.28341516 |
70 | MP0000733_abnormal_muscle_development | 1.27777377 |
71 | MP0001486_abnormal_startle_reflex | 1.27541502 |
72 | MP0005275_abnormal_skin_tensile | 1.24602190 |
73 | MP0002998_abnormal_bone_remodeling | 1.22887378 |
74 | MP0002572_abnormal_emotion/affect_behav | 1.22098649 |
75 | MP0004947_skin_inflammation | 1.22092922 |
76 | MP0000955_abnormal_spinal_cord | 1.21683037 |
77 | MP0005385_cardiovascular_system_phenoty | 1.21674028 |
78 | MP0001544_abnormal_cardiovascular_syste | 1.21674028 |
79 | MP0002332_abnormal_exercise_endurance | 1.21616973 |
80 | MP0001440_abnormal_grooming_behavior | 1.20855605 |
81 | MP0005023_abnormal_wound_healing | 1.19542921 |
82 | MP0000767_abnormal_smooth_muscle | 1.19438996 |
83 | MP0005670_abnormal_white_adipose | 1.18388627 |
84 | MP0004885_abnormal_endolymph | 1.16562280 |
85 | MP0000003_abnormal_adipose_tissue | 1.16076435 |
86 | MP0001958_emphysema | 1.15421758 |
87 | MP0004811_abnormal_neuron_physiology | 1.13407055 |
88 | MP0005257_abnormal_intraocular_pressure | 1.13193524 |
89 | MP0003950_abnormal_plasma_membrane | 1.12377642 |
90 | MP0001533_abnormal_skeleton_physiology | 1.10496465 |
91 | MP0004185_abnormal_adipocyte_glucose | 1.05961939 |
92 | MP0003633_abnormal_nervous_system | 1.05481893 |
93 | MP0004272_abnormal_basement_membrane | 1.04778839 |
94 | MP0005076_abnormal_cell_differentiation | 1.02033977 |
95 | MP0001970_abnormal_pain_threshold | 1.02026835 |
96 | MP0002108_abnormal_muscle_morphology | 1.01943317 |
97 | MP0000858_altered_metastatic_potential | 1.01654394 |
98 | MP0005375_adipose_tissue_phenotype | 1.01493423 |
99 | MP0000604_amyloidosis | 1.01267817 |
100 | MP0002733_abnormal_thermal_nociception | 1.01024899 |
101 | MP0003075_altered_response_to | 1.00986439 |
102 | MP0002234_abnormal_pharynx_morphology | 1.00976729 |
103 | MP0001968_abnormal_touch/_nociception | 1.00661644 |
104 | MP0008961_abnormal_basal_metabolism | 1.00613051 |
105 | MP0003091_abnormal_cell_migration | 1.00179460 |
106 | MP0002066_abnormal_motor_capabilities/c | 0.97851980 |
107 | MP0005167_abnormal_blood-brain_barrier | 0.97523330 |
108 | MP0008874_decreased_physiological_sensi | 0.96751966 |
109 | MP0002184_abnormal_innervation | 0.95671266 |
110 | MP0002419_abnormal_innate_immunity | 0.94986296 |
111 | MP0002882_abnormal_neuron_morphology | 0.94336283 |
112 | MP0005166_decreased_susceptibility_to | 0.93288454 |
113 | MP0002822_catalepsy | 0.92988676 |
114 | MP0002067_abnormal_sensory_capabilities | 0.92438876 |
115 | MP0001542_abnormal_bone_strength | 0.92284866 |
116 | MP0004924_abnormal_behavior | 0.91290704 |
117 | MP0005386_behavior/neurological_phenoty | 0.91290704 |
118 | MP0000579_abnormal_nail_morphology | 0.91259989 |
119 | MP0001348_abnormal_lacrimal_gland | 0.91228524 |
120 | MP0005595_abnormal_vascular_smooth | 0.90784061 |
121 | MP0003631_nervous_system_phenotype | 0.88732063 |
122 | MP0002735_abnormal_chemical_nociception | 0.86902475 |
123 | MP0003566_abnormal_cell_adhesion | 0.86189130 |
124 | MP0010368_abnormal_lymphatic_system | 0.85822797 |
125 | MP0001501_abnormal_sleep_pattern | 0.85576912 |
126 | MP0005503_abnormal_tendon_morphology | 0.84505592 |
127 | MP0003283_abnormal_digestive_organ | 0.84490648 |
128 | MP0002896_abnormal_bone_mineralization | 0.83517209 |
129 | MP0003045_fibrosis | 0.82381691 |
130 | MP0006082_CNS_inflammation | 0.80418765 |
131 | MP0005666_abnormal_adipose_tissue | 0.79261310 |
132 | MP0005390_skeleton_phenotype | 0.78410705 |
133 | MP0003448_altered_tumor_morphology | 0.78267244 |
134 | MP0003303_peritoneal_inflammation | 0.76946957 |
135 | MP0003632_abnormal_nervous_system | 0.76321221 |
136 | MP0002060_abnormal_skin_morphology | 0.75904491 |
137 | MP0003221_abnormal_cardiomyocyte_apopto | 0.74863318 |
138 | MP0002736_abnormal_nociception_after | 0.74859311 |
139 | MP0005025_abnormal_response_to | 0.71749366 |
140 | MP0005000_abnormal_immune_tolerance | 0.71707747 |
141 | MP0000685_abnormal_immune_system | 0.71054177 |
142 | MP0002249_abnormal_larynx_morphology | 0.67627500 |
143 | MP0003724_increased_susceptibility_to | 0.67570590 |
144 | MP0000678_abnormal_parathyroid_gland | 0.67473557 |
145 | MP0005165_increased_susceptibility_to | 0.67341757 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sudden death (HP:0001699) | 4.27959118 |
2 | Muscle fiber splitting (HP:0003555) | 4.27776391 |
3 | Hyporeflexia of lower limbs (HP:0002600) | 3.97283025 |
4 | Difficulty running (HP:0009046) | 3.83060172 |
5 | Exercise-induced myalgia (HP:0003738) | 3.68194864 |
6 | Calf muscle hypertrophy (HP:0008981) | 3.57575733 |
7 | Muscle hypertrophy of the lower extremities (HP:0008968) | 3.51459029 |
8 | Abnormality of the calf musculature (HP:0001430) | 3.37036623 |
9 | Supranuclear gaze palsy (HP:0000605) | 3.36507957 |
10 | Obstructive sleep apnea (HP:0002870) | 3.31967935 |
11 | EMG: myopathic abnormalities (HP:0003458) | 3.29392859 |
12 | Exercise-induced muscle cramps (HP:0003710) | 3.28533797 |
13 | Myokymia (HP:0002411) | 3.28469803 |
14 | Increased variability in muscle fiber diameter (HP:0003557) | 3.10007302 |
15 | Bundle branch block (HP:0011710) | 3.09583493 |
16 | Neurofibrillary tangles (HP:0002185) | 3.02107124 |
17 | Atrial fibrillation (HP:0005110) | 2.98301561 |
18 | Distal lower limb muscle weakness (HP:0009053) | 2.93500518 |
19 | Ventricular tachycardia (HP:0004756) | 2.91238458 |
20 | Increased connective tissue (HP:0009025) | 2.88976600 |
21 | Primary atrial arrhythmia (HP:0001692) | 2.86781031 |
22 | Type 1 muscle fiber predominance (HP:0003803) | 2.85401350 |
23 | Difficulty climbing stairs (HP:0003551) | 2.84064676 |
24 | Broad metatarsal (HP:0001783) | 2.81157556 |
25 | Cerebral inclusion bodies (HP:0100314) | 2.80618148 |
26 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.76927151 |
27 | Myotonia (HP:0002486) | 2.72113689 |
28 | Shallow orbits (HP:0000586) | 2.69685461 |
29 | Premature rupture of membranes (HP:0001788) | 2.69267481 |
30 | Supraventricular arrhythmia (HP:0005115) | 2.69059190 |
31 | Supraventricular tachycardia (HP:0004755) | 2.68768275 |
32 | Lower limb amyotrophy (HP:0007210) | 2.62866071 |
33 | Atrophic scars (HP:0001075) | 2.55234692 |
34 | Ventricular fibrillation (HP:0001663) | 2.53379717 |
35 | Scapular winging (HP:0003691) | 2.52599781 |
36 | Rapidly progressive (HP:0003678) | 2.51775542 |
37 | Prolonged QT interval (HP:0001657) | 2.50342533 |
38 | Action tremor (HP:0002345) | 2.49855889 |
39 | Subaortic stenosis (HP:0001682) | 2.48497973 |
40 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.48497973 |
41 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.46810708 |
42 | Fragile skin (HP:0001030) | 2.42839848 |
43 | Muscle fiber inclusion bodies (HP:0100299) | 2.42111438 |
44 | Distal lower limb amyotrophy (HP:0008944) | 2.38410364 |
45 | Ankle clonus (HP:0011448) | 2.38324671 |
46 | Asymmetric septal hypertrophy (HP:0001670) | 2.37316534 |
47 | Upper limb amyotrophy (HP:0009129) | 2.37195956 |
48 | Distal upper limb amyotrophy (HP:0007149) | 2.37195956 |
49 | Syncope (HP:0001279) | 2.36805566 |
50 | Insidious onset (HP:0003587) | 2.36360010 |
51 | Termporal pattern (HP:0011008) | 2.36360010 |
52 | Achilles tendon contracture (HP:0001771) | 2.36336115 |
53 | Focal motor seizures (HP:0011153) | 2.34056584 |
54 | Protrusio acetabuli (HP:0003179) | 2.32172626 |
55 | Right ventricular cardiomyopathy (HP:0011663) | 2.32082251 |
56 | Round ear (HP:0100830) | 2.31273148 |
57 | Focal seizures (HP:0007359) | 2.30823240 |
58 | Foot dorsiflexor weakness (HP:0009027) | 2.30470154 |
59 | Cerebral aneurysm (HP:0004944) | 2.27042600 |
60 | Slender build (HP:0001533) | 2.24553809 |
61 | Abnormality of the foot musculature (HP:0001436) | 2.22592315 |
62 | Ventricular arrhythmia (HP:0004308) | 2.22275591 |
63 | Heart block (HP:0012722) | 2.20733965 |
64 | Abnormal atrioventricular conduction (HP:0005150) | 2.19956805 |
65 | Mitral regurgitation (HP:0001653) | 2.19547879 |
66 | Visual hallucinations (HP:0002367) | 2.18571116 |
67 | Dysmetria (HP:0001310) | 2.18486277 |
68 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.15875957 |
69 | Lipoatrophy (HP:0100578) | 2.15409518 |
70 | Myopathic facies (HP:0002058) | 2.14156677 |
71 | Genu recurvatum (HP:0002816) | 2.14088289 |
72 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.13879505 |
73 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.13879505 |
74 | Abnormality of glycolipid metabolism (HP:0010969) | 2.13879505 |
75 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.13566539 |
76 | Gowers sign (HP:0003391) | 2.11689538 |
77 | Vertebral compression fractures (HP:0002953) | 2.07007756 |
78 | Onion bulb formation (HP:0003383) | 2.06217782 |
79 | Pheochromocytoma (HP:0002666) | 2.05567324 |
80 | Vascular tortuosity (HP:0004948) | 2.04881920 |
81 | Abnormality of the Achilles tendon (HP:0005109) | 2.04100647 |
82 | Atrioventricular block (HP:0001678) | 2.03752794 |
83 | Aortic aneurysm (HP:0004942) | 2.02923311 |
84 | Arterial tortuosity (HP:0005116) | 2.00319919 |
85 | Limb-girdle muscle atrophy (HP:0003797) | 1.99911051 |
86 | Turricephaly (HP:0000262) | 1.99556084 |
87 | Abnormality of the corticospinal tract (HP:0002492) | 1.99428098 |
88 | Myoglobinuria (HP:0002913) | 1.98484429 |
89 | Urinary urgency (HP:0000012) | 1.98445586 |
90 | Ulnar deviation of the wrist (HP:0003049) | 1.96352866 |
91 | Disproportionate tall stature (HP:0001519) | 1.96337640 |
92 | Abnormal EKG (HP:0003115) | 1.95446269 |
93 | Bladder diverticulum (HP:0000015) | 1.94591469 |
94 | Aneurysm (HP:0002617) | 1.92460442 |
95 | Insomnia (HP:0100785) | 1.92107619 |
96 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.91091839 |
97 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.91091839 |
98 | Spinal rigidity (HP:0003306) | 1.91073688 |
99 | Nemaline bodies (HP:0003798) | 1.89934313 |
100 | Muscle stiffness (HP:0003552) | 1.88466123 |
101 | Dysmetric saccades (HP:0000641) | 1.87795986 |
102 | Depression (HP:0000716) | 1.87215135 |
103 | Dysdiadochokinesis (HP:0002075) | 1.87178030 |
104 | Intention tremor (HP:0002080) | 1.86965388 |
105 | Lower limb muscle weakness (HP:0007340) | 1.86697834 |
106 | Bulbar palsy (HP:0001283) | 1.86287216 |
107 | Megalencephaly (HP:0001355) | 1.85834007 |
108 | Neuronal loss in central nervous system (HP:0002529) | 1.85519809 |
109 | Axonal loss (HP:0003447) | 1.85199070 |
110 | Apathy (HP:0000741) | 1.84615019 |
111 | Ankle contracture (HP:0006466) | 1.84526855 |
112 | Dilatation of the ascending aorta (HP:0005111) | 1.84495831 |
113 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.84097933 |
114 | Aplasia of the phalanges of the hand (HP:0009802) | 1.84097933 |
115 | Aplasia involving bones of the extremities (HP:0009825) | 1.84097933 |
116 | Broad face (HP:0000283) | 1.83278679 |
117 | Eczematoid dermatitis (HP:0000976) | 1.82304483 |
118 | Nuclear cataract (HP:0100018) | 1.81481588 |
119 | Neck muscle weakness (HP:0000467) | 1.80842815 |
120 | Annular pancreas (HP:0001734) | 1.80563950 |
121 | Frequent falls (HP:0002359) | 1.78469904 |
122 | Dilated cardiomyopathy (HP:0001644) | 1.77109469 |
123 | Diplopia (HP:0000651) | 1.77058777 |
124 | Abnormality of binocular vision (HP:0011514) | 1.77058777 |
125 | Ulnar bowing (HP:0003031) | 1.76185809 |
126 | Hammertoe (HP:0001765) | 1.76064345 |
127 | Postural instability (HP:0002172) | 1.74932348 |
128 | Hyperacusis (HP:0010780) | 1.74013121 |
129 | Cellulitis (HP:0100658) | 1.74004728 |
130 | Spastic gait (HP:0002064) | 1.73447216 |
131 | Bronchomalacia (HP:0002780) | 1.73340298 |
132 | Urinary bladder sphincter dysfunction (HP:0002839) | 1.73124647 |
133 | Diminished motivation (HP:0000745) | 1.70610653 |
134 | Peritonitis (HP:0002586) | 1.69872119 |
135 | Mitral valve prolapse (HP:0001634) | 1.69775325 |
136 | Wormian bones (HP:0002645) | 1.68312480 |
137 | Easy fatigability (HP:0003388) | 1.68007471 |
138 | Dysostosis multiplex (HP:0000943) | 1.67492948 |
139 | Hypercortisolism (HP:0001578) | 1.66360850 |
140 | Blue sclerae (HP:0000592) | 1.65554767 |
141 | Aortic dissection (HP:0002647) | 1.65187833 |
142 | Hypoventilation (HP:0002791) | 1.64162222 |
143 | Generalized amyotrophy (HP:0003700) | 1.62324323 |
144 | Cervical subluxation (HP:0003308) | 1.60469876 |
145 | Thin bony cortex (HP:0002753) | 1.60042972 |
146 | Increased IgE level (HP:0003212) | 1.58740832 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 3.20640309 |
2 | TRIB3 | 2.93070440 |
3 | PHKG1 | 2.55408525 |
4 | PHKG2 | 2.55408525 |
5 | PAK6 | 2.34147633 |
6 | MAP3K9 | 2.26403063 |
7 | DMPK | 2.10811477 |
8 | ERN1 | 2.06826895 |
9 | PRKD3 | 2.01518600 |
10 | MAP2K3 | 1.93267596 |
11 | MAP3K11 | 1.92965340 |
12 | EPHB1 | 1.91495422 |
13 | RIPK1 | 1.89635937 |
14 | IRAK3 | 1.88587782 |
15 | MARK1 | 1.83615370 |
16 | KSR2 | 1.81967781 |
17 | NTRK1 | 1.81246883 |
18 | EPHA4 | 1.77479569 |
19 | NTRK3 | 1.72658942 |
20 | LMTK2 | 1.67242129 |
21 | PKN2 | 1.63026899 |
22 | ARAF | 1.60081419 |
23 | ICK | 1.56898549 |
24 | TYRO3 | 1.54620997 |
25 | STK39 | 1.51462219 |
26 | PRPF4B | 1.50050609 |
27 | SMG1 | 1.49626515 |
28 | PDGFRA | 1.45297097 |
29 | MAP3K13 | 1.45268065 |
30 | PAK3 | 1.45236828 |
31 | EEF2K | 1.42545614 |
32 | LATS2 | 1.38930434 |
33 | MINK1 | 1.37794247 |
34 | DAPK2 | 1.35934458 |
35 | UHMK1 | 1.35256777 |
36 | CAMKK1 | 1.33923117 |
37 | PKN1 | 1.28618653 |
38 | DDR2 | 1.28391131 |
39 | TAOK2 | 1.27095122 |
40 | WNK1 | 1.25150120 |
41 | ROCK2 | 1.24870340 |
42 | MAP3K3 | 1.21346105 |
43 | PRKCH | 1.19901902 |
44 | NTRK2 | 1.19183145 |
45 | MAP3K4 | 1.16850158 |
46 | LIMK1 | 1.15207678 |
47 | PRKD1 | 1.14021444 |
48 | BMX | 1.13352342 |
49 | RPS6KA2 | 1.12608366 |
50 | CDK5 | 1.11161178 |
51 | OBSCN | 1.10293589 |
52 | MARK2 | 1.09110664 |
53 | TAOK1 | 1.07708199 |
54 | TESK1 | 1.05354741 |
55 | RET | 1.02783904 |
56 | EPHB2 | 1.01333719 |
57 | MAP3K7 | 1.01182087 |
58 | TGFBR2 | 1.00444599 |
59 | CAMK1G | 0.99245001 |
60 | SIK2 | 0.98082267 |
61 | PTK2B | 0.97992023 |
62 | CDK19 | 0.96955979 |
63 | ALK | 0.95948302 |
64 | MAP3K6 | 0.93931652 |
65 | CAMK2D | 0.93448763 |
66 | MAP4K1 | 0.89800157 |
67 | ROCK1 | 0.89746451 |
68 | STK38 | 0.89461165 |
69 | STK11 | 0.88983275 |
70 | OXSR1 | 0.88648449 |
71 | DAPK3 | 0.85813102 |
72 | MAP2K4 | 0.85349926 |
73 | ZAP70 | 0.85179028 |
74 | PDPK1 | 0.84806639 |
75 | FGFR2 | 0.84805538 |
76 | PINK1 | 0.84708484 |
77 | CDK12 | 0.83155570 |
78 | CDK14 | 0.81744433 |
79 | ILK | 0.80840014 |
80 | CDK15 | 0.80663210 |
81 | KSR1 | 0.80562439 |
82 | PTK6 | 0.80237166 |
83 | MUSK | 0.77961547 |
84 | CDC42BPA | 0.76890966 |
85 | TBK1 | 0.76131542 |
86 | CDK18 | 0.75764638 |
87 | CAMK1D | 0.75747693 |
88 | SGK3 | 0.74942953 |
89 | PTK2 | 0.73847421 |
90 | CSK | 0.72824133 |
91 | CAMK2A | 0.72270645 |
92 | MTOR | 0.71981767 |
93 | BRAF | 0.70824903 |
94 | CDK11A | 0.69977116 |
95 | WNK4 | 0.69666798 |
96 | RPS6KC1 | 0.68498015 |
97 | RPS6KL1 | 0.68498015 |
98 | MAPKAPK5 | 0.68308314 |
99 | CAMK2B | 0.68122113 |
100 | PDGFRB | 0.67499874 |
101 | MAPK12 | 0.67428210 |
102 | MAPK4 | 0.64970701 |
103 | MAP3K1 | 0.64128197 |
104 | PRKG2 | 0.63736110 |
105 | MAP3K2 | 0.63523446 |
106 | FER | 0.63491554 |
107 | IRAK4 | 0.61422285 |
108 | MET | 0.59632658 |
109 | IRAK2 | 0.59373287 |
110 | FGFR4 | 0.59066004 |
111 | CAMK1 | 0.59031803 |
112 | SGK494 | 0.58959177 |
113 | SGK223 | 0.58959177 |
114 | CAMK2G | 0.57954334 |
115 | MAPK7 | 0.57121788 |
116 | FYN | 0.56149353 |
117 | FES | 0.56063354 |
118 | FGR | 0.54614903 |
119 | PDK1 | 0.54040106 |
120 | TNK2 | 0.53463296 |
121 | SIK3 | 0.53359290 |
122 | HIPK2 | 0.52686218 |
123 | TYK2 | 0.51919473 |
124 | MOS | 0.50699444 |
125 | ABL2 | 0.49914130 |
126 | PAK2 | 0.48192404 |
127 | MAP3K10 | 0.47874708 |
128 | RPS6KA6 | 0.47746527 |
129 | CAMK4 | 0.47568182 |
130 | PAK4 | 0.46810586 |
131 | SIK1 | 0.46421081 |
132 | CAMKK2 | 0.46174513 |
133 | DYRK1B | 0.45431118 |
134 | PRKD2 | 0.45014876 |
135 | PRKCE | 0.44506977 |
136 | TIE1 | 0.44150594 |
137 | MAP2K1 | 0.43189577 |
138 | SGK1 | 0.43042548 |
139 | JAK3 | 0.42425885 |
140 | RIPK4 | 0.41746527 |
141 | MYLK | 0.41725940 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.31366318 |
2 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.96216076 |
3 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.92318178 |
4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.74607303 |
5 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.72765546 |
6 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.72153658 |
7 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.71615016 |
8 | Circadian entrainment_Homo sapiens_hsa04713 | 1.69225983 |
9 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.69205800 |
10 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.57992579 |
11 | GABAergic synapse_Homo sapiens_hsa04727 | 1.56908003 |
12 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.53038768 |
13 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.49849024 |
14 | Long-term potentiation_Homo sapiens_hsa04720 | 1.49796898 |
15 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.49086313 |
16 | Olfactory transduction_Homo sapiens_hsa04740 | 1.48283721 |
17 | Axon guidance_Homo sapiens_hsa04360 | 1.47229436 |
18 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.45203166 |
19 | Salivary secretion_Homo sapiens_hsa04970 | 1.41052225 |
20 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.38327726 |
21 | Morphine addiction_Homo sapiens_hsa05032 | 1.37787175 |
22 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.37409992 |
23 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.37289415 |
24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.36393884 |
25 | Gap junction_Homo sapiens_hsa04540 | 1.33206706 |
26 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.33030903 |
27 | Other glycan degradation_Homo sapiens_hsa00511 | 1.30917743 |
28 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.29403194 |
29 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.28837255 |
30 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.27043495 |
31 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.26060664 |
32 | Renin secretion_Homo sapiens_hsa04924 | 1.24900170 |
33 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.24844788 |
34 | Nicotine addiction_Homo sapiens_hsa05033 | 1.22272072 |
35 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.21350250 |
36 | Insulin secretion_Homo sapiens_hsa04911 | 1.20843556 |
37 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.20748038 |
38 | Long-term depression_Homo sapiens_hsa04730 | 1.19098074 |
39 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.17136171 |
40 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.16641422 |
41 | Cocaine addiction_Homo sapiens_hsa05030 | 1.16278148 |
42 | Focal adhesion_Homo sapiens_hsa04510 | 1.15915837 |
43 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.15082190 |
44 | Bladder cancer_Homo sapiens_hsa05219 | 1.12389032 |
45 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.12028991 |
46 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.11160664 |
47 | Glioma_Homo sapiens_hsa05214 | 1.10687876 |
48 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.10379830 |
49 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.09561706 |
50 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.08603029 |
51 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.07168017 |
52 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.05852821 |
53 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.02872486 |
54 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.02598498 |
55 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.02454250 |
56 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.01662720 |
57 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.01088786 |
58 | Malaria_Homo sapiens_hsa05144 | 0.99670256 |
59 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.98482083 |
60 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.98402903 |
61 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.98256986 |
62 | Endocytosis_Homo sapiens_hsa04144 | 0.96235877 |
63 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.95822058 |
64 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.95221765 |
65 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.93720297 |
66 | Melanogenesis_Homo sapiens_hsa04916 | 0.92954026 |
67 | Leishmaniasis_Homo sapiens_hsa05140 | 0.92435447 |
68 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.91131053 |
69 | Tuberculosis_Homo sapiens_hsa05152 | 0.91031110 |
70 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.90650173 |
71 | Lysosome_Homo sapiens_hsa04142 | 0.90069877 |
72 | Tight junction_Homo sapiens_hsa04530 | 0.89316365 |
73 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.89169347 |
74 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.88208438 |
75 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.88175404 |
76 | Amoebiasis_Homo sapiens_hsa05146 | 0.87446042 |
77 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.86784112 |
78 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.86407235 |
79 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.86119631 |
80 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.83705003 |
81 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.80431210 |
82 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.78641576 |
83 | Viral myocarditis_Homo sapiens_hsa05416 | 0.78205093 |
84 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.77841314 |
85 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.77791060 |
86 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.77596137 |
87 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.75814845 |
88 | Taste transduction_Homo sapiens_hsa04742 | 0.74256888 |
89 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.72871720 |
90 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.72857331 |
91 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.72412202 |
92 | Shigellosis_Homo sapiens_hsa05131 | 0.71274902 |
93 | Phagosome_Homo sapiens_hsa04145 | 0.70755179 |
94 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.70451856 |
95 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.70423153 |
96 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.70226394 |
97 | Prion diseases_Homo sapiens_hsa05020 | 0.69991238 |
98 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.69573831 |
99 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.65635016 |
100 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.65294073 |
101 | Pertussis_Homo sapiens_hsa05133 | 0.65171541 |
102 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.64570341 |
103 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.64265487 |
104 | Apoptosis_Homo sapiens_hsa04210 | 0.64127817 |
105 | Platelet activation_Homo sapiens_hsa04611 | 0.64022015 |
106 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.63660101 |
107 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.63209329 |
108 | Salmonella infection_Homo sapiens_hsa05132 | 0.61909265 |
109 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.59147109 |
110 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.58187827 |
111 | Insulin resistance_Homo sapiens_hsa04931 | 0.57891743 |
112 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.57584960 |
113 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.55862141 |
114 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.52804973 |
115 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.52670583 |
116 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.51648922 |
117 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.51480312 |
118 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.51297897 |
119 | Adherens junction_Homo sapiens_hsa04520 | 0.51204593 |
120 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.51034602 |
121 | Endometrial cancer_Homo sapiens_hsa05213 | 0.50857677 |
122 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.50647554 |
123 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.49514962 |
124 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.49271808 |
125 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.48288245 |
126 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.46795751 |
127 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.46772884 |