MAP7D1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane repair (GO:0001778)4.52867223
2synaptic vesicle maturation (GO:0016188)3.95975357
3negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.88040466
4negative regulation of erythrocyte differentiation (GO:0045647)3.86564814
5negative regulation of potassium ion transmembrane transport (GO:1901380)3.66109364
6axon ensheathment in central nervous system (GO:0032291)3.63058230
7central nervous system myelination (GO:0022010)3.63058230
8sarcomere organization (GO:0045214)3.58774228
9cytoskeletal anchoring at plasma membrane (GO:0007016)3.49910526
10cardiac myofibril assembly (GO:0055003)3.46979591
11regulation of synapse structural plasticity (GO:0051823)3.45101852
12cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.43976013
13regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.42460839
14locomotory exploration behavior (GO:0035641)3.33623264
15cell communication by electrical coupling (GO:0010644)3.30962564
16barbed-end actin filament capping (GO:0051016)3.29115830
17regulation of early endosome to late endosome transport (GO:2000641)3.27424547
18positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.26902247
19regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.25556787
20layer formation in cerebral cortex (GO:0021819)3.22888784
21membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.21008580
22sodium ion export (GO:0071436)3.17303889
23myofibril assembly (GO:0030239)3.16090349
24regulation of short-term neuronal synaptic plasticity (GO:0048172)3.09261914
25protein localization to endosome (GO:0036010)3.07675091
26positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.07290275
27regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.07036956
28negative regulation of protein localization to cell surface (GO:2000009)3.06637557
29cell-substrate junction assembly (GO:0007044)3.00031405
30cell-substrate adherens junction assembly (GO:0007045)2.94806435
31focal adhesion assembly (GO:0048041)2.94806435
32regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.94389211
33actin-myosin filament sliding (GO:0033275)2.94179641
34muscle filament sliding (GO:0030049)2.94179641
35adherens junction assembly (GO:0034333)2.93948722
36cell communication involved in cardiac conduction (GO:0086065)2.92285171
37dendritic spine morphogenesis (GO:0060997)2.89461997
38cardiac muscle contraction (GO:0060048)2.89390336
39potassium ion import (GO:0010107)2.88871224
40regulation of membrane repolarization (GO:0060306)2.88797724
41sarcoplasmic reticulum calcium ion transport (GO:0070296)2.82937008
42activation of protein kinase A activity (GO:0034199)2.82532435
43regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.81849152
44regulation of NFAT protein import into nucleus (GO:0051532)2.81573624
45positive regulation of myotube differentiation (GO:0010831)2.81369400
46vocalization behavior (GO:0071625)2.80515346
47synaptic vesicle exocytosis (GO:0016079)2.78874282
48regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.78132469
49stress fiber assembly (GO:0043149)2.77899124
50cell-cell junction maintenance (GO:0045217)2.77834962
51neuronal action potential propagation (GO:0019227)2.76567019
52cellular response to epinephrine stimulus (GO:0071872)2.76194217
53glutamate secretion (GO:0014047)2.76098764
54cellular response to monoamine stimulus (GO:0071868)2.76008803
55cellular response to catecholamine stimulus (GO:0071870)2.76008803
56positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.75327842
57regulation of calcium ion transmembrane transport (GO:1903169)2.74975801
58regulation of calcium ion transmembrane transporter activity (GO:1901019)2.74975801
59G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.74476264
60vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.74305389
61regulation of cell communication by electrical coupling (GO:0010649)2.72340730
62dendrite morphogenesis (GO:0048813)2.72071381
63hemidesmosome assembly (GO:0031581)2.71794306
64regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.71113104
65ensheathment of neurons (GO:0007272)2.70544642
66axon ensheathment (GO:0008366)2.70544642
67cellular potassium ion homeostasis (GO:0030007)2.70108276
68cortical actin cytoskeleton organization (GO:0030866)2.69843736
69membrane tubulation (GO:0097320)2.68199046
70positive regulation of protein dephosphorylation (GO:0035307)2.67819531
71activation of MAPKKK activity (GO:0000185)2.67609211
72positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.66958686
73myelination (GO:0042552)2.66931577
74establishment of nucleus localization (GO:0040023)2.66646788
75regulation of actin filament-based movement (GO:1903115)2.66123051
76actomyosin structure organization (GO:0031032)2.65910406
77creatine metabolic process (GO:0006600)2.65683843
78positive regulation of receptor recycling (GO:0001921)2.63099668
79positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.56957891
80regulation of synaptic vesicle exocytosis (GO:2000300)2.56516205
81neuromuscular process controlling balance (GO:0050885)2.53430927
82cerebellar Purkinje cell layer development (GO:0021680)2.53359464
83glycine transport (GO:0015816)2.53358342
84neuronal ion channel clustering (GO:0045161)2.50980314
85cell migration in hindbrain (GO:0021535)2.50885151
86positive regulation of potassium ion transmembrane transport (GO:1901381)2.50437971
87negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.49849019
88neuron recognition (GO:0008038)2.49633049
89nerve growth factor signaling pathway (GO:0038180)2.49353710
90regulation of ARF GTPase activity (GO:0032312)2.48504805
91neuromuscular junction development (GO:0007528)2.48381934
92signal complex assembly (GO:0007172)2.46734513
93adenosine receptor signaling pathway (GO:0001973)2.46535694
94protein targeting to plasma membrane (GO:0072661)2.45723116
95axonal fasciculation (GO:0007413)2.44503054
96mannose metabolic process (GO:0006013)2.44130828
97positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.43688487
98peptidyl-tyrosine autophosphorylation (GO:0038083)2.43453134
99regulation of ARF protein signal transduction (GO:0032012)2.43377202
100regulation of glutamate receptor signaling pathway (GO:1900449)2.41853405
101establishment of mitochondrion localization (GO:0051654)2.41680763
102regulation of neuronal synaptic plasticity (GO:0048168)2.41037437
103synaptic vesicle docking involved in exocytosis (GO:0016081)2.40640482
104striated muscle contraction (GO:0006941)2.39791781
105skin morphogenesis (GO:0043589)2.39142077
106positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.38049127
107ventricular cardiac muscle cell action potential (GO:0086005)2.37348399
108peripheral nervous system axon ensheathment (GO:0032292)2.36977256
109myelination in peripheral nervous system (GO:0022011)2.36977256
110cell migration involved in heart development (GO:0060973)2.36781230
111L-amino acid import (GO:0043092)2.36718665
112actin-mediated cell contraction (GO:0070252)2.36611015
113negative regulation of cell killing (GO:0031342)2.35344195
114negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.35344195
115cortical cytoskeleton organization (GO:0030865)2.33304989
116positive regulation of potassium ion transport (GO:0043268)2.32858282
117regulation of voltage-gated calcium channel activity (GO:1901385)2.32805048
118negative regulation of cell size (GO:0045792)2.31032653
119response to muramyl dipeptide (GO:0032495)2.30417163
120dopamine receptor signaling pathway (GO:0007212)2.30108767
121regulation of striated muscle contraction (GO:0006942)2.30015025
122negative regulation of potassium ion transport (GO:0043267)2.29120447
123response to laminar fluid shear stress (GO:0034616)2.28707869
124positive regulation of axon extension (GO:0045773)2.28661692
125semaphorin-plexin signaling pathway (GO:0071526)2.28074533
126regulation of long-term neuronal synaptic plasticity (GO:0048169)2.27498804
127virion attachment to host cell (GO:0019062)2.26975566
128adhesion of symbiont to host cell (GO:0044650)2.26975566
129exploration behavior (GO:0035640)2.26795091
130actin filament-based movement (GO:0030048)2.26781460
131membrane depolarization during action potential (GO:0086010)2.26189735
132ionotropic glutamate receptor signaling pathway (GO:0035235)2.25763952
133regulation of synaptic vesicle transport (GO:1902803)2.25703475
134regulation of dendritic spine morphogenesis (GO:0061001)2.25700723
135cerebellar granule cell differentiation (GO:0021707)2.24979723
136regulation of skeletal muscle contraction (GO:0014819)2.24405894
137positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.24369506
138positive regulation of blood vessel endothelial cell migration (GO:0043536)2.23687597
139regulation of cation channel activity (GO:2001257)2.23113015
140modulation by symbiont of host cellular process (GO:0044068)2.22993527
141potassium ion homeostasis (GO:0055075)2.22813417
142positive regulation of synapse maturation (GO:0090129)2.21963275
143positive regulation of Rap GTPase activity (GO:0032854)2.18101089
144positive regulation of fibroblast migration (GO:0010763)2.17493699
145substrate-dependent cell migration (GO:0006929)2.17122156
146positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.16611052
147response to monoamine (GO:0071867)2.15658086
148response to catecholamine (GO:0071869)2.15658086
149endodermal cell differentiation (GO:0035987)2.14497131
150axon extension (GO:0048675)2.14004324
151negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.13131227
152negative regulation of Ras protein signal transduction (GO:0046580)2.12703799
153regulation of macrophage cytokine production (GO:0010935)2.12125223
154apoptotic process involved in morphogenesis (GO:0060561)2.10381470
155response to parathyroid hormone (GO:0071107)2.10022706
156venous blood vessel morphogenesis (GO:0048845)2.09298427
157negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.09257360
158cell junction maintenance (GO:0034331)2.08150372
159planar cell polarity pathway involved in neural tube closure (GO:0090179)2.07809507
160adhesion of symbiont to host (GO:0044406)2.06526160
161modulation by symbiont of host immune response (GO:0052553)2.05103078
162modulation by symbiont of host defense response (GO:0052031)2.05103078
163modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.05103078

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.50451430
2TP63_17297297_ChIP-ChIP_HaCaT_Human3.12305823
3SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.51491346
4RNF2_18974828_ChIP-Seq_MESCs_Mouse2.44274356
5EZH2_18974828_ChIP-Seq_MESCs_Mouse2.44274356
6DROSHA_22980978_ChIP-Seq_HELA_Human2.38968515
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.32680941
8VDR_21846776_ChIP-Seq_THP-1_Human2.25779806
9MTF2_20144788_ChIP-Seq_MESCs_Mouse2.22577527
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.19058328
11EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.15544979
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.14093845
13MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.13634763
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.07814991
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.07730722
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.03919796
17EZH2_27294783_Chip-Seq_ESCs_Mouse2.00538926
18NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.99696617
19TCF7_22412390_ChIP-Seq_EML_Mouse1.98011035
20EZH2_27304074_Chip-Seq_ESCs_Mouse1.97485416
21SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.95041229
22SUZ12_27294783_Chip-Seq_ESCs_Mouse1.93375377
23SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.91782969
24RNF2_27304074_Chip-Seq_ESCs_Mouse1.87292404
25WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.85332479
26* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.81926409
27* KDM2B_26808549_Chip-Seq_K562_Human1.81162703
28EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.78945823
29TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.77275658
30EP300_21415370_ChIP-Seq_HL-1_Mouse1.77048347
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.76513816
32EED_16625203_ChIP-ChIP_MESCs_Mouse1.76228772
33ZFP281_18757296_ChIP-ChIP_E14_Mouse1.73884787
34TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.71077938
35THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.68847228
36TRIM28_21343339_ChIP-Seq_HEK293_Human1.68516920
37MYC_22102868_ChIP-Seq_BL_Human1.67121760
38BP1_19119308_ChIP-ChIP_Hs578T_Human1.64773399
39ESR2_21235772_ChIP-Seq_MCF-7_Human1.61382417
40RARG_19884340_ChIP-ChIP_MEFs_Mouse1.54945226
41VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.52130611
42DNAJC2_21179169_ChIP-ChIP_NT2_Human1.52071379
43ERG_21242973_ChIP-ChIP_JURKAT_Human1.51874727
44* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.50817397
45ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.49079150
46* KDM2B_26808549_Chip-Seq_DND41_Human1.48866574
47CDX2_19796622_ChIP-Seq_MESCs_Mouse1.46454129
48EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.45041927
49VDR_24763502_ChIP-Seq_THP-1_Human1.43679580
50* LXR_22292898_ChIP-Seq_THP-1_Human1.42339379
51* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.41658642
52SA1_27219007_Chip-Seq_ERYTHROID_Human1.41372319
53CTCF_27219007_Chip-Seq_ERYTHROID_Human1.40944024
54AR_21572438_ChIP-Seq_LNCaP_Human1.36406844
55IKZF1_21737484_ChIP-ChIP_HCT116_Human1.36065906
56ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.35039151
57P68_20966046_ChIP-Seq_HELA_Human1.34568246
58REST_21632747_ChIP-Seq_MESCs_Mouse1.33079260
59ESR1_20079471_ChIP-ChIP_T-47D_Human1.31880170
60TBX20_22080862_ChIP-Seq_HEART_Mouse1.31185472
61TBX20_22328084_ChIP-Seq_HEART_Mouse1.31185472
62TET1_21451524_ChIP-Seq_MESCs_Mouse1.29479807
63REST_18959480_ChIP-ChIP_MESCs_Mouse1.28586688
64RING1B_27294783_Chip-Seq_ESCs_Mouse1.25843003
65GBX2_23144817_ChIP-Seq_PC3_Human1.25783904
66SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.25621669
67STAT6_21828071_ChIP-Seq_BEAS2B_Human1.24509384
68ZFP281_27345836_Chip-Seq_ESCs_Mouse1.23999287
69CLOCK_20551151_ChIP-Seq_293T_Human1.22984332
70SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.22443834
71SRY_22984422_ChIP-ChIP_TESTIS_Rat1.21660671
72KDM2B_26808549_Chip-Seq_JURKAT_Human1.21437149
73EGR1_19374776_ChIP-ChIP_THP-1_Human1.19493663
74GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.19146087
75NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.17872106
76TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.17575173
77* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16560935
78PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.15569674
79* MAF_26560356_Chip-Seq_TH1_Human1.15019323
80GATA1_19941827_ChIP-Seq_MEL_Mouse1.14955986
81E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.12419754
82* CTCF_27219007_Chip-Seq_Bcells_Human1.12236754
83SMC1_22415368_ChIP-Seq_MEFs_Mouse1.12174432
84TP53_22127205_ChIP-Seq_IMR90_Human1.12083765
85* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.11947341
86SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.11241667
87* ELK3_25401928_ChIP-Seq_HUVEC_Human1.09772885
88ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.09642105
89NR3C1_23031785_ChIP-Seq_PC12_Mouse1.09085381
90OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.07900864
91* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.07851546
92DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.07447483
93RING1B_27294783_Chip-Seq_NPCs_Mouse1.07184778
94BRD4_27068464_Chip-Seq_AML-cells_Mouse1.07173811
95TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.07146102
96RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.06240819
97TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.06194265
98RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.05989712
99RUNX1_22412390_ChIP-Seq_EML_Mouse1.05711960
100* SPI1_23127762_ChIP-Seq_K562_Human1.05486264
101TP53_20018659_ChIP-ChIP_R1E_Mouse1.05480950
102SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05273106
103MAF_26560356_Chip-Seq_TH2_Human1.03738450
104ZNF217_24962896_ChIP-Seq_MCF-7_Human1.03003545
105PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02066399
106* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.01622841
107TET1_21490601_ChIP-Seq_MESCs_Mouse1.01238698
108KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.00977325
109* ELF1_20517297_ChIP-Seq_JURKAT_Human1.00736879
110SMC3_22415368_ChIP-Seq_MEFs_Mouse1.00168157
111NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.99788706
112* TP63_22573176_ChIP-Seq_HFKS_Human0.98691749
113RACK7_27058665_Chip-Seq_MCF-7_Human0.98372465
114NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.98194342
115AHR_22903824_ChIP-Seq_MCF-7_Human0.97693170
116CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.97397998
117TP53_23651856_ChIP-Seq_MEFs_Mouse0.94857646
118PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.92935476
119UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.91047736
120AR_19668381_ChIP-Seq_PC3_Human0.90458785
121CREB1_26743006_Chip-Seq_LNCaP_Human0.90101869
122SOX2_21211035_ChIP-Seq_LN229_Gbm0.89939876
123RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89295567
124TP53_16413492_ChIP-PET_HCT116_Human0.89183397
125SMAD4_21741376_ChIP-Seq_HESCs_Human0.88836251
126KLF4_19829295_ChIP-Seq_ESCs_Human0.88795212
127RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.88652401
128CTNNB1_20460455_ChIP-Seq_HCT116_Human0.87885690
129PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.86769471
130GATA1_19941826_ChIP-Seq_K562_Human0.86450875
131SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86210552
132GATA2_21666600_ChIP-Seq_HMVEC_Human0.85443346
133BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.84951403
134SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84653513
135NFIB_24661679_ChIP-Seq_LUNG_Mouse0.84159581
136SMC4_20622854_ChIP-Seq_HELA_Human0.83363350
137ARNT_22903824_ChIP-Seq_MCF-7_Human0.83192319
138NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.82704797
139ISL1_27105846_Chip-Seq_CPCs_Mouse0.82479585

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.27690494
2MP0000751_myopathy3.81367713
3MP0002837_dystrophic_cardiac_calcinosis3.39269884
4MP0004270_analgesia2.65821859
5MP0004084_abnormal_cardiac_muscle2.62121227
6MP0000749_muscle_degeneration2.57290294
7MP0003880_abnormal_central_pattern2.40546668
8MP0004145_abnormal_muscle_electrophysio2.39921137
9MP0003635_abnormal_synaptic_transmissio2.33356285
10MP0005623_abnormal_meninges_morphology2.32358254
11MP0004036_abnormal_muscle_relaxation2.25944819
12MP0005451_abnormal_body_composition2.25412369
13MP0003828_pulmonary_edema2.15795752
14MP0008438_abnormal_cutaneous_collagen2.13366547
15MP0003646_muscle_fatigue2.10028848
16MP0004087_abnormal_muscle_fiber2.09526196
17MP0000747_muscle_weakness2.07352177
18MP0009840_abnormal_foam_cell2.06985683
19MP0003329_amyloid_beta_deposits2.03687277
20MP0004215_abnormal_myocardial_fiber1.98949490
21MP0004858_abnormal_nervous_system1.98358553
22MP0005058_abnormal_lysosome_morphology1.96959178
23MP0003300_gastrointestinal_ulcer1.94461648
24MP0000920_abnormal_myelination1.94326265
25MP0003436_decreased_susceptibility_to1.91786460
26MP0005330_cardiomyopathy1.89636835
27MP0002064_seizures1.82950462
28MP0003137_abnormal_impulse_conducting1.78112224
29MP0004510_myositis1.76905444
30MP0000750_abnormal_muscle_regeneration1.74210706
31MP0001849_ear_inflammation1.72435312
32MP0002063_abnormal_learning/memory/cond1.68478544
33MP0000759_abnormal_skeletal_muscle1.67873981
34MP0002106_abnormal_muscle_physiology1.66078258
35MP0005409_darkened_coat_color1.64646555
36MP0009780_abnormal_chondrocyte_physiolo1.64506232
37MP0004130_abnormal_muscle_cell1.62868841
38MP0003705_abnormal_hypodermis_morpholog1.62824446
39MP0005620_abnormal_muscle_contractility1.61345722
40MP0002972_abnormal_cardiac_muscle1.61234062
41MP0009745_abnormal_behavioral_response1.59844204
42MP0002877_abnormal_melanocyte_morpholog1.59786793
43MP0009046_muscle_twitch1.59486409
44MP0008569_lethality_at_weaning1.57006823
45MP0003172_abnormal_lysosome_physiology1.53387942
46MP0009278_abnormal_bone_marrow1.52275400
47MP0008260_abnormal_autophagy1.50911986
48MP0005369_muscle_phenotype1.46335624
49MP0002272_abnormal_nervous_system1.46333750
50MP0003191_abnormal_cellular_cholesterol1.46202351
51MP0002269_muscular_atrophy1.46008120
52MP0005423_abnormal_somatic_nervous1.44688344
53MP0000343_altered_response_to1.43779636
54MP0004085_abnormal_heartbeat1.42708907
55MP0003690_abnormal_glial_cell1.40887647
56MP0004233_abnormal_muscle_weight1.40597085
57MP0000013_abnormal_adipose_tissue1.38485168
58MP0004484_altered_response_of1.37404168
59MP0001299_abnormal_eye_distance/1.34606142
60MP0002909_abnormal_adrenal_gland1.33941799
61MP0006138_congestive_heart_failure1.32498444
62MP0000778_abnormal_nervous_system1.32248845
63MP0003634_abnormal_glial_cell1.31880764
64MP0003453_abnormal_keratinocyte_physiol1.30422983
65MP0008775_abnormal_heart_ventricle1.30156359
66MP0003279_aneurysm1.29627743
67MP0010630_abnormal_cardiac_muscle1.29467171
68MP0002734_abnormal_mechanical_nocicepti1.28718895
69MP0003879_abnormal_hair_cell1.28341516
70MP0000733_abnormal_muscle_development1.27777377
71MP0001486_abnormal_startle_reflex1.27541502
72MP0005275_abnormal_skin_tensile1.24602190
73MP0002998_abnormal_bone_remodeling1.22887378
74MP0002572_abnormal_emotion/affect_behav1.22098649
75MP0004947_skin_inflammation1.22092922
76MP0000955_abnormal_spinal_cord1.21683037
77MP0005385_cardiovascular_system_phenoty1.21674028
78MP0001544_abnormal_cardiovascular_syste1.21674028
79MP0002332_abnormal_exercise_endurance1.21616973
80MP0001440_abnormal_grooming_behavior1.20855605
81MP0005023_abnormal_wound_healing1.19542921
82MP0000767_abnormal_smooth_muscle1.19438996
83MP0005670_abnormal_white_adipose1.18388627
84MP0004885_abnormal_endolymph1.16562280
85MP0000003_abnormal_adipose_tissue1.16076435
86MP0001958_emphysema1.15421758
87MP0004811_abnormal_neuron_physiology1.13407055
88MP0005257_abnormal_intraocular_pressure1.13193524
89MP0003950_abnormal_plasma_membrane1.12377642
90MP0001533_abnormal_skeleton_physiology1.10496465
91MP0004185_abnormal_adipocyte_glucose1.05961939
92MP0003633_abnormal_nervous_system1.05481893
93MP0004272_abnormal_basement_membrane1.04778839
94MP0005076_abnormal_cell_differentiation1.02033977
95MP0001970_abnormal_pain_threshold1.02026835
96MP0002108_abnormal_muscle_morphology1.01943317
97MP0000858_altered_metastatic_potential1.01654394
98MP0005375_adipose_tissue_phenotype1.01493423
99MP0000604_amyloidosis1.01267817
100MP0002733_abnormal_thermal_nociception1.01024899
101MP0003075_altered_response_to1.00986439
102MP0002234_abnormal_pharynx_morphology1.00976729
103MP0001968_abnormal_touch/_nociception1.00661644
104MP0008961_abnormal_basal_metabolism1.00613051
105MP0003091_abnormal_cell_migration1.00179460
106MP0002066_abnormal_motor_capabilities/c0.97851980
107MP0005167_abnormal_blood-brain_barrier0.97523330
108MP0008874_decreased_physiological_sensi0.96751966
109MP0002184_abnormal_innervation0.95671266
110MP0002419_abnormal_innate_immunity0.94986296
111MP0002882_abnormal_neuron_morphology0.94336283
112MP0005166_decreased_susceptibility_to0.93288454
113MP0002822_catalepsy0.92988676
114MP0002067_abnormal_sensory_capabilities0.92438876
115MP0001542_abnormal_bone_strength0.92284866
116MP0004924_abnormal_behavior0.91290704
117MP0005386_behavior/neurological_phenoty0.91290704
118MP0000579_abnormal_nail_morphology0.91259989
119MP0001348_abnormal_lacrimal_gland0.91228524
120MP0005595_abnormal_vascular_smooth0.90784061
121MP0003631_nervous_system_phenotype0.88732063
122MP0002735_abnormal_chemical_nociception0.86902475
123MP0003566_abnormal_cell_adhesion0.86189130
124MP0010368_abnormal_lymphatic_system0.85822797
125MP0001501_abnormal_sleep_pattern0.85576912
126MP0005503_abnormal_tendon_morphology0.84505592
127MP0003283_abnormal_digestive_organ0.84490648
128MP0002896_abnormal_bone_mineralization0.83517209
129MP0003045_fibrosis0.82381691
130MP0006082_CNS_inflammation0.80418765
131MP0005666_abnormal_adipose_tissue0.79261310
132MP0005390_skeleton_phenotype0.78410705
133MP0003448_altered_tumor_morphology0.78267244
134MP0003303_peritoneal_inflammation0.76946957
135MP0003632_abnormal_nervous_system0.76321221
136MP0002060_abnormal_skin_morphology0.75904491
137MP0003221_abnormal_cardiomyocyte_apopto0.74863318
138MP0002736_abnormal_nociception_after0.74859311
139MP0005025_abnormal_response_to0.71749366
140MP0005000_abnormal_immune_tolerance0.71707747
141MP0000685_abnormal_immune_system0.71054177
142MP0002249_abnormal_larynx_morphology0.67627500
143MP0003724_increased_susceptibility_to0.67570590
144MP0000678_abnormal_parathyroid_gland0.67473557
145MP0005165_increased_susceptibility_to0.67341757

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)4.27959118
2Muscle fiber splitting (HP:0003555)4.27776391
3Hyporeflexia of lower limbs (HP:0002600)3.97283025
4Difficulty running (HP:0009046)3.83060172
5Exercise-induced myalgia (HP:0003738)3.68194864
6Calf muscle hypertrophy (HP:0008981)3.57575733
7Muscle hypertrophy of the lower extremities (HP:0008968)3.51459029
8Abnormality of the calf musculature (HP:0001430)3.37036623
9Supranuclear gaze palsy (HP:0000605)3.36507957
10Obstructive sleep apnea (HP:0002870)3.31967935
11EMG: myopathic abnormalities (HP:0003458)3.29392859
12Exercise-induced muscle cramps (HP:0003710)3.28533797
13Myokymia (HP:0002411)3.28469803
14Increased variability in muscle fiber diameter (HP:0003557)3.10007302
15Bundle branch block (HP:0011710)3.09583493
16Neurofibrillary tangles (HP:0002185)3.02107124
17Atrial fibrillation (HP:0005110)2.98301561
18Distal lower limb muscle weakness (HP:0009053)2.93500518
19Ventricular tachycardia (HP:0004756)2.91238458
20Increased connective tissue (HP:0009025)2.88976600
21Primary atrial arrhythmia (HP:0001692)2.86781031
22Type 1 muscle fiber predominance (HP:0003803)2.85401350
23Difficulty climbing stairs (HP:0003551)2.84064676
24Broad metatarsal (HP:0001783)2.81157556
25Cerebral inclusion bodies (HP:0100314)2.80618148
26Abnormality of skeletal muscle fiber size (HP:0012084)2.76927151
27Myotonia (HP:0002486)2.72113689
28Shallow orbits (HP:0000586)2.69685461
29Premature rupture of membranes (HP:0001788)2.69267481
30Supraventricular arrhythmia (HP:0005115)2.69059190
31Supraventricular tachycardia (HP:0004755)2.68768275
32Lower limb amyotrophy (HP:0007210)2.62866071
33Atrophic scars (HP:0001075)2.55234692
34Ventricular fibrillation (HP:0001663)2.53379717
35Scapular winging (HP:0003691)2.52599781
36Rapidly progressive (HP:0003678)2.51775542
37Prolonged QT interval (HP:0001657)2.50342533
38Action tremor (HP:0002345)2.49855889
39Subaortic stenosis (HP:0001682)2.48497973
40Abnormality of the left ventricular outflow tract (HP:0011103)2.48497973
41Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.46810708
42Fragile skin (HP:0001030)2.42839848
43Muscle fiber inclusion bodies (HP:0100299)2.42111438
44Distal lower limb amyotrophy (HP:0008944)2.38410364
45Ankle clonus (HP:0011448)2.38324671
46Asymmetric septal hypertrophy (HP:0001670)2.37316534
47Upper limb amyotrophy (HP:0009129)2.37195956
48Distal upper limb amyotrophy (HP:0007149)2.37195956
49Syncope (HP:0001279)2.36805566
50Insidious onset (HP:0003587)2.36360010
51Termporal pattern (HP:0011008)2.36360010
52Achilles tendon contracture (HP:0001771)2.36336115
53Focal motor seizures (HP:0011153)2.34056584
54Protrusio acetabuli (HP:0003179)2.32172626
55Right ventricular cardiomyopathy (HP:0011663)2.32082251
56Round ear (HP:0100830)2.31273148
57Focal seizures (HP:0007359)2.30823240
58Foot dorsiflexor weakness (HP:0009027)2.30470154
59Cerebral aneurysm (HP:0004944)2.27042600
60Slender build (HP:0001533)2.24553809
61Abnormality of the foot musculature (HP:0001436)2.22592315
62Ventricular arrhythmia (HP:0004308)2.22275591
63Heart block (HP:0012722)2.20733965
64Abnormal atrioventricular conduction (HP:0005150)2.19956805
65Mitral regurgitation (HP:0001653)2.19547879
66Visual hallucinations (HP:0002367)2.18571116
67Dysmetria (HP:0001310)2.18486277
68Centrally nucleated skeletal muscle fibers (HP:0003687)2.15875957
69Lipoatrophy (HP:0100578)2.15409518
70Myopathic facies (HP:0002058)2.14156677
71Genu recurvatum (HP:0002816)2.14088289
72Abnormality of liposaccharide metabolism (HP:0010968)2.13879505
73Abnormality of glycosphingolipid metabolism (HP:0004343)2.13879505
74Abnormality of glycolipid metabolism (HP:0010969)2.13879505
75Mildly elevated creatine phosphokinase (HP:0008180)2.13566539
76Gowers sign (HP:0003391)2.11689538
77Vertebral compression fractures (HP:0002953)2.07007756
78Onion bulb formation (HP:0003383)2.06217782
79Pheochromocytoma (HP:0002666)2.05567324
80Vascular tortuosity (HP:0004948)2.04881920
81Abnormality of the Achilles tendon (HP:0005109)2.04100647
82Atrioventricular block (HP:0001678)2.03752794
83Aortic aneurysm (HP:0004942)2.02923311
84Arterial tortuosity (HP:0005116)2.00319919
85Limb-girdle muscle atrophy (HP:0003797)1.99911051
86Turricephaly (HP:0000262)1.99556084
87Abnormality of the corticospinal tract (HP:0002492)1.99428098
88Myoglobinuria (HP:0002913)1.98484429
89Urinary urgency (HP:0000012)1.98445586
90Ulnar deviation of the wrist (HP:0003049)1.96352866
91Disproportionate tall stature (HP:0001519)1.96337640
92Abnormal EKG (HP:0003115)1.95446269
93Bladder diverticulum (HP:0000015)1.94591469
94Aneurysm (HP:0002617)1.92460442
95Insomnia (HP:0100785)1.92107619
96Degeneration of the lateral corticospinal tracts (HP:0002314)1.91091839
97Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.91091839
98Spinal rigidity (HP:0003306)1.91073688
99Nemaline bodies (HP:0003798)1.89934313
100Muscle stiffness (HP:0003552)1.88466123
101Dysmetric saccades (HP:0000641)1.87795986
102Depression (HP:0000716)1.87215135
103Dysdiadochokinesis (HP:0002075)1.87178030
104Intention tremor (HP:0002080)1.86965388
105Lower limb muscle weakness (HP:0007340)1.86697834
106Bulbar palsy (HP:0001283)1.86287216
107Megalencephaly (HP:0001355)1.85834007
108Neuronal loss in central nervous system (HP:0002529)1.85519809
109Axonal loss (HP:0003447)1.85199070
110Apathy (HP:0000741)1.84615019
111Ankle contracture (HP:0006466)1.84526855
112Dilatation of the ascending aorta (HP:0005111)1.84495831
113Aplasia involving bones of the upper limbs (HP:0009823)1.84097933
114Aplasia of the phalanges of the hand (HP:0009802)1.84097933
115Aplasia involving bones of the extremities (HP:0009825)1.84097933
116Broad face (HP:0000283)1.83278679
117Eczematoid dermatitis (HP:0000976)1.82304483
118Nuclear cataract (HP:0100018)1.81481588
119Neck muscle weakness (HP:0000467)1.80842815
120Annular pancreas (HP:0001734)1.80563950
121Frequent falls (HP:0002359)1.78469904
122Dilated cardiomyopathy (HP:0001644)1.77109469
123Diplopia (HP:0000651)1.77058777
124Abnormality of binocular vision (HP:0011514)1.77058777
125Ulnar bowing (HP:0003031)1.76185809
126Hammertoe (HP:0001765)1.76064345
127Postural instability (HP:0002172)1.74932348
128Hyperacusis (HP:0010780)1.74013121
129Cellulitis (HP:0100658)1.74004728
130Spastic gait (HP:0002064)1.73447216
131Bronchomalacia (HP:0002780)1.73340298
132Urinary bladder sphincter dysfunction (HP:0002839)1.73124647
133Diminished motivation (HP:0000745)1.70610653
134Peritonitis (HP:0002586)1.69872119
135Mitral valve prolapse (HP:0001634)1.69775325
136Wormian bones (HP:0002645)1.68312480
137Easy fatigability (HP:0003388)1.68007471
138Dysostosis multiplex (HP:0000943)1.67492948
139Hypercortisolism (HP:0001578)1.66360850
140Blue sclerae (HP:0000592)1.65554767
141Aortic dissection (HP:0002647)1.65187833
142Hypoventilation (HP:0002791)1.64162222
143Generalized amyotrophy (HP:0003700)1.62324323
144Cervical subluxation (HP:0003308)1.60469876
145Thin bony cortex (HP:0002753)1.60042972
146Increased IgE level (HP:0003212)1.58740832

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN3.20640309
2TRIB32.93070440
3PHKG12.55408525
4PHKG22.55408525
5PAK62.34147633
6MAP3K92.26403063
7DMPK2.10811477
8ERN12.06826895
9PRKD32.01518600
10MAP2K31.93267596
11MAP3K111.92965340
12EPHB11.91495422
13RIPK11.89635937
14IRAK31.88587782
15MARK11.83615370
16KSR21.81967781
17NTRK11.81246883
18EPHA41.77479569
19NTRK31.72658942
20LMTK21.67242129
21PKN21.63026899
22ARAF1.60081419
23ICK1.56898549
24TYRO31.54620997
25STK391.51462219
26PRPF4B1.50050609
27SMG11.49626515
28PDGFRA1.45297097
29MAP3K131.45268065
30PAK31.45236828
31EEF2K1.42545614
32LATS21.38930434
33MINK11.37794247
34DAPK21.35934458
35UHMK11.35256777
36CAMKK11.33923117
37PKN11.28618653
38DDR21.28391131
39TAOK21.27095122
40WNK11.25150120
41ROCK21.24870340
42MAP3K31.21346105
43PRKCH1.19901902
44NTRK21.19183145
45MAP3K41.16850158
46LIMK11.15207678
47PRKD11.14021444
48BMX1.13352342
49RPS6KA21.12608366
50CDK51.11161178
51OBSCN1.10293589
52MARK21.09110664
53TAOK11.07708199
54TESK11.05354741
55RET1.02783904
56EPHB21.01333719
57MAP3K71.01182087
58TGFBR21.00444599
59CAMK1G0.99245001
60SIK20.98082267
61PTK2B0.97992023
62CDK190.96955979
63ALK0.95948302
64MAP3K60.93931652
65CAMK2D0.93448763
66MAP4K10.89800157
67ROCK10.89746451
68STK380.89461165
69STK110.88983275
70OXSR10.88648449
71DAPK30.85813102
72MAP2K40.85349926
73ZAP700.85179028
74PDPK10.84806639
75FGFR20.84805538
76PINK10.84708484
77CDK120.83155570
78CDK140.81744433
79ILK0.80840014
80CDK150.80663210
81KSR10.80562439
82PTK60.80237166
83MUSK0.77961547
84CDC42BPA0.76890966
85TBK10.76131542
86CDK180.75764638
87CAMK1D0.75747693
88SGK30.74942953
89PTK20.73847421
90CSK0.72824133
91CAMK2A0.72270645
92MTOR0.71981767
93BRAF0.70824903
94CDK11A0.69977116
95WNK40.69666798
96RPS6KC10.68498015
97RPS6KL10.68498015
98MAPKAPK50.68308314
99CAMK2B0.68122113
100PDGFRB0.67499874
101MAPK120.67428210
102MAPK40.64970701
103MAP3K10.64128197
104PRKG20.63736110
105MAP3K20.63523446
106FER0.63491554
107IRAK40.61422285
108MET0.59632658
109IRAK20.59373287
110FGFR40.59066004
111CAMK10.59031803
112SGK4940.58959177
113SGK2230.58959177
114CAMK2G0.57954334
115MAPK70.57121788
116FYN0.56149353
117FES0.56063354
118FGR0.54614903
119PDK10.54040106
120TNK20.53463296
121SIK30.53359290
122HIPK20.52686218
123TYK20.51919473
124MOS0.50699444
125ABL20.49914130
126PAK20.48192404
127MAP3K100.47874708
128RPS6KA60.47746527
129CAMK40.47568182
130PAK40.46810586
131SIK10.46421081
132CAMKK20.46174513
133DYRK1B0.45431118
134PRKD20.45014876
135PRKCE0.44506977
136TIE10.44150594
137MAP2K10.43189577
138SGK10.43042548
139JAK30.42425885
140RIPK40.41746527
141MYLK0.41725940

Predicted pathways (KEGG)

RankGene SetZ-score
1Dilated cardiomyopathy_Homo sapiens_hsa054142.31366318
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.96216076
3Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.92318178
4Cardiac muscle contraction_Homo sapiens_hsa042601.74607303
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.72765546
6Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.72153658
7Synaptic vesicle cycle_Homo sapiens_hsa047211.71615016
8Circadian entrainment_Homo sapiens_hsa047131.69225983
9Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.69205800
10Glutamatergic synapse_Homo sapiens_hsa047241.57992579
11GABAergic synapse_Homo sapiens_hsa047271.56908003
12Gastric acid secretion_Homo sapiens_hsa049711.53038768
13Osteoclast differentiation_Homo sapiens_hsa043801.49849024
14Long-term potentiation_Homo sapiens_hsa047201.49796898
15Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.49086313
16Olfactory transduction_Homo sapiens_hsa047401.48283721
17Axon guidance_Homo sapiens_hsa043601.47229436
18Oxytocin signaling pathway_Homo sapiens_hsa049211.45203166
19Salivary secretion_Homo sapiens_hsa049701.41052225
20Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.38327726
21Morphine addiction_Homo sapiens_hsa050321.37787175
22Cholinergic synapse_Homo sapiens_hsa047251.37409992
23Acute myeloid leukemia_Homo sapiens_hsa052211.37289415
24Nitrogen metabolism_Homo sapiens_hsa009101.36393884
25Gap junction_Homo sapiens_hsa045401.33206706
26Notch signaling pathway_Homo sapiens_hsa043301.33030903
27Other glycan degradation_Homo sapiens_hsa005111.30917743
28Dopaminergic synapse_Homo sapiens_hsa047281.29403194
29Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.28837255
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.27043495
31GnRH signaling pathway_Homo sapiens_hsa049121.26060664
32Renin secretion_Homo sapiens_hsa049241.24900170
33Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.24844788
34Nicotine addiction_Homo sapiens_hsa050331.22272072
35B cell receptor signaling pathway_Homo sapiens_hsa046621.21350250
36Insulin secretion_Homo sapiens_hsa049111.20843556
37Dorso-ventral axis formation_Homo sapiens_hsa043201.20748038
38Long-term depression_Homo sapiens_hsa047301.19098074
39Renal cell carcinoma_Homo sapiens_hsa052111.17136171
40Amphetamine addiction_Homo sapiens_hsa050311.16641422
41Cocaine addiction_Homo sapiens_hsa050301.16278148
42Focal adhesion_Homo sapiens_hsa045101.15915837
43Type II diabetes mellitus_Homo sapiens_hsa049301.15082190
44Bladder cancer_Homo sapiens_hsa052191.12389032
45Toll-like receptor signaling pathway_Homo sapiens_hsa046201.12028991
46Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.11160664
47Glioma_Homo sapiens_hsa052141.10687876
48cGMP-PKG signaling pathway_Homo sapiens_hsa040221.10379830
49Estrogen signaling pathway_Homo sapiens_hsa049151.09561706
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.08603029
51Phospholipase D signaling pathway_Homo sapiens_hsa040721.07168017
52Calcium signaling pathway_Homo sapiens_hsa040201.05852821
53cAMP signaling pathway_Homo sapiens_hsa040241.02872486
54Vascular smooth muscle contraction_Homo sapiens_hsa042701.02598498
55VEGF signaling pathway_Homo sapiens_hsa043701.02454250
56Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.01662720
57Pancreatic cancer_Homo sapiens_hsa052121.01088786
58Malaria_Homo sapiens_hsa051440.99670256
59Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.98482083
60Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.98402903
61Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.98256986
62Endocytosis_Homo sapiens_hsa041440.96235877
63ErbB signaling pathway_Homo sapiens_hsa040120.95822058
64ECM-receptor interaction_Homo sapiens_hsa045120.95221765
65TNF signaling pathway_Homo sapiens_hsa046680.93720297
66Melanogenesis_Homo sapiens_hsa049160.92954026
67Leishmaniasis_Homo sapiens_hsa051400.92435447
68Glycosaminoglycan degradation_Homo sapiens_hsa005310.91131053
69Tuberculosis_Homo sapiens_hsa051520.91031110
70Proteoglycans in cancer_Homo sapiens_hsa052050.90650173
71Lysosome_Homo sapiens_hsa041420.90069877
72Tight junction_Homo sapiens_hsa045300.89316365
73Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.89169347
74Regulation of actin cytoskeleton_Homo sapiens_hsa048100.88208438
75Toxoplasmosis_Homo sapiens_hsa051450.88175404
76Amoebiasis_Homo sapiens_hsa051460.87446042
77Neurotrophin signaling pathway_Homo sapiens_hsa047220.86784112
78Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.86407235
79Serotonergic synapse_Homo sapiens_hsa047260.86119631
80MAPK signaling pathway_Homo sapiens_hsa040100.83705003
81Rap1 signaling pathway_Homo sapiens_hsa040150.80431210
82Phosphatidylinositol signaling system_Homo sapiens_hsa040700.78641576
83Viral myocarditis_Homo sapiens_hsa054160.78205093
84Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.77841314
85Prolactin signaling pathway_Homo sapiens_hsa049170.77791060
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.77596137
87T cell receptor signaling pathway_Homo sapiens_hsa046600.75814845
88Taste transduction_Homo sapiens_hsa047420.74256888
892-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.72871720
90Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.72857331
91Insulin signaling pathway_Homo sapiens_hsa049100.72412202
92Shigellosis_Homo sapiens_hsa051310.71274902
93Phagosome_Homo sapiens_hsa041450.70755179
94Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70451856
95Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70423153
96Ras signaling pathway_Homo sapiens_hsa040140.70226394
97Prion diseases_Homo sapiens_hsa050200.69991238
98Adipocytokine signaling pathway_Homo sapiens_hsa049200.69573831
99AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65635016
100Inositol phosphate metabolism_Homo sapiens_hsa005620.65294073
101Pertussis_Homo sapiens_hsa051330.65171541
102Choline metabolism in cancer_Homo sapiens_hsa052310.64570341
103Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.64265487
104Apoptosis_Homo sapiens_hsa042100.64127817
105Platelet activation_Homo sapiens_hsa046110.64022015
106mTOR signaling pathway_Homo sapiens_hsa041500.63660101
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63209329
108Salmonella infection_Homo sapiens_hsa051320.61909265
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59147109
110Longevity regulating pathway - mammal_Homo sapiens_hsa042110.58187827
111Insulin resistance_Homo sapiens_hsa049310.57891743
112Chronic myeloid leukemia_Homo sapiens_hsa052200.57584960
113Pancreatic secretion_Homo sapiens_hsa049720.55862141
114Glucagon signaling pathway_Homo sapiens_hsa049220.52804973
115Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.52670583
116AMPK signaling pathway_Homo sapiens_hsa041520.51648922
117Vibrio cholerae infection_Homo sapiens_hsa051100.51480312
118Hippo signaling pathway_Homo sapiens_hsa043900.51297897
119Adherens junction_Homo sapiens_hsa045200.51204593
120Leukocyte transendothelial migration_Homo sapiens_hsa046700.51034602
121Endometrial cancer_Homo sapiens_hsa052130.50857677
122Central carbon metabolism in cancer_Homo sapiens_hsa052300.50647554
123Non-small cell lung cancer_Homo sapiens_hsa052230.49514962
124Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49271808
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.48288245
126Chemokine signaling pathway_Homo sapiens_hsa040620.46795751
127Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.46772884

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