MAP9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.77790472
2vocalization behavior (GO:0071625)5.64671883
3neuron cell-cell adhesion (GO:0007158)5.52565856
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.36865321
5synaptic vesicle exocytosis (GO:0016079)5.21791679
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.21349118
7protein localization to synapse (GO:0035418)5.16924575
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.14406179
9locomotory exploration behavior (GO:0035641)4.92495833
10regulation of glutamate receptor signaling pathway (GO:1900449)4.91541184
11glutamate secretion (GO:0014047)4.89910203
12synaptic vesicle maturation (GO:0016188)4.88395515
13presynaptic membrane assembly (GO:0097105)4.78196290
14regulation of synaptic vesicle exocytosis (GO:2000300)4.70252105
15ionotropic glutamate receptor signaling pathway (GO:0035235)4.69455627
16presynaptic membrane organization (GO:0097090)4.64736657
17layer formation in cerebral cortex (GO:0021819)4.59062586
18exploration behavior (GO:0035640)4.42560231
19regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.40519747
20synaptic vesicle docking involved in exocytosis (GO:0016081)4.40465420
21neuron recognition (GO:0008038)4.39681900
22glutamate receptor signaling pathway (GO:0007215)4.29836187
23dendritic spine morphogenesis (GO:0060997)4.29060350
24postsynaptic membrane organization (GO:0001941)4.21176534
25synaptic transmission, glutamatergic (GO:0035249)4.18442260
26regulation of synaptic vesicle transport (GO:1902803)4.16965724
27epithelial cilium movement (GO:0003351)4.11995717
28regulation of long-term neuronal synaptic plasticity (GO:0048169)4.09338040
29neurotransmitter-gated ion channel clustering (GO:0072578)4.02782286
30neuron-neuron synaptic transmission (GO:0007270)4.02663148
31neurotransmitter secretion (GO:0007269)3.99193147
32axonal fasciculation (GO:0007413)3.93558697
33regulation of neuronal synaptic plasticity (GO:0048168)3.91008436
34cilium movement (GO:0003341)3.89669567
35axonemal dynein complex assembly (GO:0070286)3.88506892
36epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.82976912
37neuronal action potential propagation (GO:0019227)3.81482539
38regulation of synapse structural plasticity (GO:0051823)3.76147397
39regulation of excitatory postsynaptic membrane potential (GO:0060079)3.72558507
40proline transport (GO:0015824)3.69525647
41regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.69446508
42positive regulation of synapse maturation (GO:0090129)3.64763880
43positive regulation of membrane potential (GO:0045838)3.60640206
44regulation of postsynaptic membrane potential (GO:0060078)3.60093483
45gamma-aminobutyric acid signaling pathway (GO:0007214)3.59640513
46regulation of dendritic spine morphogenesis (GO:0061001)3.52352460
47long-term memory (GO:0007616)3.49298707
48transmission of nerve impulse (GO:0019226)3.46303408
49pyrimidine nucleobase catabolic process (GO:0006208)3.45890432
50synaptic vesicle endocytosis (GO:0048488)3.45689392
51dendrite morphogenesis (GO:0048813)3.44131833
52positive regulation of synapse assembly (GO:0051965)3.39777250
53negative regulation of synaptic transmission, GABAergic (GO:0032229)3.38718597
54cell migration in hindbrain (GO:0021535)3.38504184
55synapse assembly (GO:0007416)3.38124381
56regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.38060139
57long-term synaptic potentiation (GO:0060291)3.35268858
58central nervous system projection neuron axonogenesis (GO:0021952)3.33601690
59response to histamine (GO:0034776)3.33002609
60gamma-aminobutyric acid transport (GO:0015812)3.32708255
61regulation of vesicle fusion (GO:0031338)3.32611285
62regulation of synaptic plasticity (GO:0048167)3.31728304
63neurotransmitter transport (GO:0006836)3.31269771
64intraciliary transport (GO:0042073)3.29049765
65regulation of neurotransmitter secretion (GO:0046928)3.24517016
66positive regulation of synaptic transmission, GABAergic (GO:0032230)3.24500161
67regulation of synaptic transmission, glutamatergic (GO:0051966)3.22722346
68protein localization to cilium (GO:0061512)3.21743210
69activation of protein kinase A activity (GO:0034199)3.19866368
70positive regulation of neurotransmitter secretion (GO:0001956)3.19063899
71auditory behavior (GO:0031223)3.17835739
72membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.16409059
73behavioral defense response (GO:0002209)3.15979418
74behavioral fear response (GO:0001662)3.15979418
75negative regulation of cytosolic calcium ion concentration (GO:0051481)3.15313985
76regulation of dendritic spine development (GO:0060998)3.14114346
77positive regulation of dendritic spine morphogenesis (GO:0061003)3.13583679
78innervation (GO:0060384)3.12525221
79neuron fate determination (GO:0048664)3.12293088
80cerebellar granule cell differentiation (GO:0021707)3.11746702
81fear response (GO:0042596)3.09224787
82positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.08490046
83positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.06473946
84startle response (GO:0001964)3.06366126
85cilium or flagellum-dependent cell motility (GO:0001539)3.06225345
86G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.05817473
87positive regulation of dendritic spine development (GO:0060999)3.05503459
88social behavior (GO:0035176)3.02481834
89intraspecies interaction between organisms (GO:0051703)3.02481834
90G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.02309511
91nucleobase catabolic process (GO:0046113)3.00926305
92learning (GO:0007612)2.99775712
93dendritic spine organization (GO:0097061)2.99762942
94synapse organization (GO:0050808)2.99235869
95retinal ganglion cell axon guidance (GO:0031290)2.99109424
96dendrite development (GO:0016358)2.98934452
97regulation of neurotransmitter levels (GO:0001505)2.98722116
98negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.98144822
99membrane depolarization (GO:0051899)2.97794209
100organelle transport along microtubule (GO:0072384)2.97523556
101cerebellar Purkinje cell differentiation (GO:0021702)2.96983671
102detection of calcium ion (GO:0005513)2.96336960
103cellular potassium ion homeostasis (GO:0030007)2.96064246
104positive regulation of neurotransmitter transport (GO:0051590)2.95869047
105regulation of synapse assembly (GO:0051963)2.93694461
106regulation of neurotransmitter transport (GO:0051588)2.92911897
107vesicle transport along microtubule (GO:0047496)2.92555258
108regulation of respiratory system process (GO:0044065)2.91650638
109response to auditory stimulus (GO:0010996)2.91035979
110nonmotile primary cilium assembly (GO:0035058)2.90761508
111regulation of synapse maturation (GO:0090128)2.89723379
112central nervous system myelination (GO:0022010)2.88207435
113axon ensheathment in central nervous system (GO:0032291)2.88207435
114membrane hyperpolarization (GO:0060081)2.88005857
115retinal cone cell development (GO:0046549)2.84911297
116cochlea development (GO:0090102)2.80280021
117neurofilament cytoskeleton organization (GO:0060052)2.79901833
118axoneme assembly (GO:0035082)2.76804986
119cilium organization (GO:0044782)2.74244374
120mechanosensory behavior (GO:0007638)2.72769837
121behavioral response to nicotine (GO:0035095)2.72678859
122cilium assembly (GO:0042384)2.69351354
123cilium morphogenesis (GO:0060271)2.60145640
124behavioral response to cocaine (GO:0048148)2.59643074
125regulation of calcium ion-dependent exocytosis (GO:0017158)2.57050187
126short-term memory (GO:0007614)2.55854852
127regulation of cilium movement (GO:0003352)2.55235808
128primary amino compound metabolic process (GO:1901160)2.55131816
129substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.53511207
130substrate-independent telencephalic tangential migration (GO:0021826)2.53511207
131membrane depolarization during action potential (GO:0086010)2.50685672
132positive regulation of meiosis (GO:0045836)2.47228416
133regulation of meiosis I (GO:0060631)2.46162293
134serotonin metabolic process (GO:0042428)2.46127237
135neuronal action potential (GO:0019228)2.38379328
136cerebral cortex radially oriented cell migration (GO:0021799)2.37355119
137motile cilium assembly (GO:0044458)2.36737819
138C4-dicarboxylate transport (GO:0015740)2.36056012
139urinary tract smooth muscle contraction (GO:0014848)2.34603374
140adult walking behavior (GO:0007628)2.33211922
141mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.33150319
142regulation of microtubule-based movement (GO:0060632)2.33091239
143neuronal ion channel clustering (GO:0045161)2.30368578
144regulation of feeding behavior (GO:0060259)2.29776668
145relaxation of smooth muscle (GO:0044557)2.29311781
146positive regulation of meiotic cell cycle (GO:0051446)2.26967624
147potassium ion import (GO:0010107)2.25483666

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.91552832
2GBX2_23144817_ChIP-Seq_PC3_Human3.99263150
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.03920949
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.02176719
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.87277955
6REST_21632747_ChIP-Seq_MESCs_Mouse2.63080567
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.59593531
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.52322326
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.52306379
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.52306379
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.51810126
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.43059129
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.38213420
14SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.34335645
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.31505820
16GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.29224055
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.23915213
18CTBP2_25329375_ChIP-Seq_LNCAP_Human2.22018295
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.20600101
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.16308502
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.14329284
22RARB_27405468_Chip-Seq_BRAIN_Mouse2.12972369
23SUZ12_27294783_Chip-Seq_ESCs_Mouse2.12392957
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.09893020
25TAF15_26573619_Chip-Seq_HEK293_Human2.08931308
26DROSHA_22980978_ChIP-Seq_HELA_Human2.07280210
27REST_18959480_ChIP-ChIP_MESCs_Mouse2.06575307
28AR_21572438_ChIP-Seq_LNCaP_Human2.01084078
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.99168486
30ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.95068461
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.85354164
32SMAD4_21799915_ChIP-Seq_A2780_Human1.78058085
33FLI1_27457419_Chip-Seq_LIVER_Mouse1.70892809
34SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.70546618
35EWS_26573619_Chip-Seq_HEK293_Human1.70258023
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.69053403
37P300_19829295_ChIP-Seq_ESCs_Human1.67056719
38BMI1_23680149_ChIP-Seq_NPCS_Mouse1.61232226
39FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.58841567
40ZNF274_21170338_ChIP-Seq_K562_Hela1.57862330
41IKZF1_21737484_ChIP-ChIP_HCT116_Human1.55624557
42IGF1R_20145208_ChIP-Seq_DFB_Human1.54748409
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.54267470
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.53324740
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.49450222
46SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.46670467
47TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45066197
48FUS_26573619_Chip-Seq_HEK293_Human1.43367789
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.42673493
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.41965070
51PCGF2_27294783_Chip-Seq_ESCs_Mouse1.40914503
52RNF2_27304074_Chip-Seq_NSC_Mouse1.40053461
53OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39907945
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.39695581
55PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.39372773
56NR3C1_23031785_ChIP-Seq_PC12_Mouse1.37637875
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.37575872
58* SOX2_21211035_ChIP-Seq_LN229_Gbm1.36097332
59RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.35649955
60AR_25329375_ChIP-Seq_VCAP_Human1.35165015
61SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31992704
62EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30614787
63STAT3_23295773_ChIP-Seq_U87_Human1.29730604
64GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27428210
65MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.25651871
66RING1B_27294783_Chip-Seq_ESCs_Mouse1.24552832
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.24471952
68CBP_20019798_ChIP-Seq_JUKART_Human1.24471952
69SALL1_21062744_ChIP-ChIP_HESCs_Human1.24051048
70VDR_22108803_ChIP-Seq_LS180_Human1.22507766
71ARNT_22903824_ChIP-Seq_MCF-7_Human1.22059142
72TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21078945
73MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.19924616
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.19388492
75ERG_21242973_ChIP-ChIP_JURKAT_Human1.18717347
76BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.18271014
77* TCF4_23295773_ChIP-Seq_U87_Human1.15803438
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15313677
79CDX2_19796622_ChIP-Seq_MESCs_Mouse1.15035878
80AR_19668381_ChIP-Seq_PC3_Human1.15028506
81P53_22127205_ChIP-Seq_FIBROBLAST_Human1.14969623
82RING1B_27294783_Chip-Seq_NPCs_Mouse1.13763030
83EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13534136
84AHR_22903824_ChIP-Seq_MCF-7_Human1.13301158
85KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12886591
86ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12843223
87KLF5_20875108_ChIP-Seq_MESCs_Mouse1.12281899
88RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.10775936
89CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10689950
90P53_22387025_ChIP-Seq_ESCs_Mouse1.10363768
91YAP1_20516196_ChIP-Seq_MESCs_Mouse1.10112330
92TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09826975
93POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09826975
94* RUNX2_22187159_ChIP-Seq_PCA_Human1.09675507
95SUZ12_27294783_Chip-Seq_NPCs_Mouse1.08967419
96RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.07804798
97LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07627960
98ER_23166858_ChIP-Seq_MCF-7_Human1.07269676
99PRDM14_20953172_ChIP-Seq_ESCs_Human1.06748903
100POU5F1_16153702_ChIP-ChIP_HESCs_Human1.05640561
101JUN_21703547_ChIP-Seq_K562_Human1.05057548
102CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05000079
103TAL1_26923725_Chip-Seq_HPCs_Mouse1.04731192
104TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03172585
105TCF4_22108803_ChIP-Seq_LS180_Human1.03063570
106MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02561433
107NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02451772
108HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.02246318
109TP53_18474530_ChIP-ChIP_U2OS_Human1.00688042
110TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99227914
111FLI1_21867929_ChIP-Seq_TH2_Mouse0.99040121
112E2F1_18555785_Chip-Seq_ESCs_Mouse0.98880154
113WT1_25993318_ChIP-Seq_PODOCYTE_Human0.98702989
114RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.98524282
115NANOG_18555785_Chip-Seq_ESCs_Mouse0.98185080
116SMAD3_21741376_ChIP-Seq_ESCs_Human0.97391511
117RBPJ_22232070_ChIP-Seq_NCS_Mouse0.95920967
118TP53_16413492_ChIP-PET_HCT116_Human0.91894776
119TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.90754277
120BCAT_22108803_ChIP-Seq_LS180_Human0.90551015
121TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.88761916
122KDM2B_26808549_Chip-Seq_REH_Human0.87916808
123MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.86605956

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.71227615
2MP0003880_abnormal_central_pattern4.92271180
3MP0003635_abnormal_synaptic_transmissio3.95677262
4MP0004270_analgesia3.93605569
5MP0002063_abnormal_learning/memory/cond3.25517079
6MP0009745_abnormal_behavioral_response3.22384606
7MP0001968_abnormal_touch/_nociception3.04910318
8MP0002064_seizures2.85658055
9MP0002572_abnormal_emotion/affect_behav2.81489288
10MP0002734_abnormal_mechanical_nocicepti2.75119504
11MP0005423_abnormal_somatic_nervous2.72650515
12MP0009046_muscle_twitch2.67146677
13MP0001486_abnormal_startle_reflex2.46815944
14MP0002736_abnormal_nociception_after2.39519615
15MP0002735_abnormal_chemical_nociception2.36137511
16MP0002272_abnormal_nervous_system2.33005743
17MP0001440_abnormal_grooming_behavior2.29495193
18MP0000778_abnormal_nervous_system2.29457103
19MP0006276_abnormal_autonomic_nervous2.20500571
20MP0002733_abnormal_thermal_nociception2.16097696
21MP0009780_abnormal_chondrocyte_physiolo2.07948825
22MP0001501_abnormal_sleep_pattern2.03682030
23MP0002184_abnormal_innervation2.01279819
24MP0002067_abnormal_sensory_capabilities1.99317769
25MP0001970_abnormal_pain_threshold1.94191719
26MP0008877_abnormal_DNA_methylation1.93931929
27MP0001188_hyperpigmentation1.89364564
28MP0002557_abnormal_social/conspecific_i1.87163891
29MP0004924_abnormal_behavior1.84074968
30MP0005386_behavior/neurological_phenoty1.84074968
31MP0002822_catalepsy1.83567741
32MP0002653_abnormal_ependyma_morphology1.79119727
33MP0004811_abnormal_neuron_physiology1.70025375
34MP0001984_abnormal_olfaction1.67769633
35MP0003329_amyloid_beta_deposits1.66523973
36MP0003787_abnormal_imprinting1.65505395
37MP0002909_abnormal_adrenal_gland1.62274704
38MP0003136_yellow_coat_color1.59013530
39MP0000955_abnormal_spinal_cord1.58442048
40MP0001529_abnormal_vocalization1.58035533
41MP0005645_abnormal_hypothalamus_physiol1.57015930
42MP0005646_abnormal_pituitary_gland1.54637605
43MP0003879_abnormal_hair_cell1.50500416
44MP0008789_abnormal_olfactory_epithelium1.49703097
45MP0008569_lethality_at_weaning1.48292627
46MP0003122_maternal_imprinting1.47010942
47MP0002882_abnormal_neuron_morphology1.46814968
48MP0004858_abnormal_nervous_system1.45099064
49MP0004043_abnormal_pH_regulation1.38427835
50MP0002066_abnormal_motor_capabilities/c1.38168210
51MP0002938_white_spotting1.37302748
52MP0004133_heterotaxia1.35451830
53MP0004885_abnormal_endolymph1.33667814
54MP0001905_abnormal_dopamine_level1.32228203
55MP0005253_abnormal_eye_physiology1.29953709
56MP0003123_paternal_imprinting1.29374285
57MP0001502_abnormal_circadian_rhythm1.24525694
58MP0002152_abnormal_brain_morphology1.21101723
59MP0003283_abnormal_digestive_organ1.20475622
60MP0002160_abnormal_reproductive_system1.14499711
61MP0004142_abnormal_muscle_tone1.13618367
62MP0002837_dystrophic_cardiac_calcinosis1.12446046
63MP0003011_delayed_dark_adaptation1.11855414
64MP0010386_abnormal_urinary_bladder1.10846433
65MP0004742_abnormal_vestibular_system1.08804297
66MP0005551_abnormal_eye_electrophysiolog1.07971502
67MP0003890_abnormal_embryonic-extraembry1.07830622
68MP0000631_abnormal_neuroendocrine_gland1.07805577
69MP0003633_abnormal_nervous_system1.06233005
70MP0005248_abnormal_Harderian_gland1.05542034
71MP0002163_abnormal_gland_morphology1.01265909
72MP0000566_synostosis1.00566344
73MP0002233_abnormal_nose_morphology0.99960564
74MP0001293_anophthalmia0.97568398
75MP0000013_abnormal_adipose_tissue0.95252881
76MP0000569_abnormal_digit_pigmentation0.95145389
77MP0002928_abnormal_bile_duct0.94584142
78MP0005195_abnormal_posterior_eye0.94508680
79MP0002069_abnormal_eating/drinking_beha0.94296801
80MP0003631_nervous_system_phenotype0.93147492
81MP0003937_abnormal_limbs/digits/tail_de0.92941738
82MP0002229_neurodegeneration0.92725006
83MP0005394_taste/olfaction_phenotype0.92413724
84MP0005499_abnormal_olfactory_system0.92413724
85MP0002638_abnormal_pupillary_reflex0.92291113
86MP0000427_abnormal_hair_cycle0.92266806
87MP0001963_abnormal_hearing_physiology0.92053979
88MP0002752_abnormal_somatic_nervous0.89930620
89MP0004145_abnormal_muscle_electrophysio0.89435095
90MP0005379_endocrine/exocrine_gland_phen0.88895329
91MP0005409_darkened_coat_color0.88895230
92MP0003938_abnormal_ear_development0.88182304
93MP0003119_abnormal_digestive_system0.88100036
94MP0006072_abnormal_retinal_apoptosis0.85011064
95MP0006292_abnormal_olfactory_placode0.83899886
96MP0004085_abnormal_heartbeat0.82673375
97MP0002102_abnormal_ear_morphology0.82577353
98MP0000751_myopathy0.81374137
99MP0005187_abnormal_penis_morphology0.80307813
100MP0003861_abnormal_nervous_system0.77824499
101MP0001177_atelectasis0.76894900
102MP0003634_abnormal_glial_cell0.76870003
103MP0009379_abnormal_foot_pigmentation0.75464863
104MP0001485_abnormal_pinna_reflex0.74362744
105MP0005535_abnormal_body_temperature0.73822484
106MP0002876_abnormal_thyroid_physiology0.73117304
107MP0008872_abnormal_physiological_respon0.71543340
108MP0000026_abnormal_inner_ear0.69738846
109MP0002751_abnormal_autonomic_nervous0.67928107
110MP0003121_genomic_imprinting0.67368574
111MP0002234_abnormal_pharynx_morphology0.67308322
112MP0001664_abnormal_digestion0.65969034
113MP0003632_abnormal_nervous_system0.64318142
114MP0008874_decreased_physiological_sensi0.63231761
115MP0004233_abnormal_muscle_weight0.61888433
116MP0001943_abnormal_respiration0.60747076
117MP0000015_abnormal_ear_pigmentation0.60722358
118MP0004484_altered_response_of0.60405754
119MP0003137_abnormal_impulse_conducting0.59986808
120MP0001299_abnormal_eye_distance/0.58746466
121MP0004215_abnormal_myocardial_fiber0.58571635
122MP0002090_abnormal_vision0.56645691
123MP0010770_preweaning_lethality0.56469247
124MP0002082_postnatal_lethality0.56469247
125MP0005171_absent_coat_pigmentation0.56417739

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.83842533
2Myokymia (HP:0002411)5.53312392
3Focal seizures (HP:0007359)5.25078690
4Epileptic encephalopathy (HP:0200134)4.97878442
5Visual hallucinations (HP:0002367)4.79491926
6Atonic seizures (HP:0010819)4.57320590
7Febrile seizures (HP:0002373)4.12865428
8Hyperventilation (HP:0002883)4.02536446
9Progressive cerebellar ataxia (HP:0002073)4.01260487
10Absence seizures (HP:0002121)3.96631735
11Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.91559236
12Broad-based gait (HP:0002136)3.82905932
13Dialeptic seizures (HP:0011146)3.64022957
14Nephronophthisis (HP:0000090)3.58267913
15Generalized tonic-clonic seizures (HP:0002069)3.47863699
16Abnormal respiratory motile cilium morphology (HP:0005938)3.46820130
17Abnormal respiratory epithelium morphology (HP:0012253)3.46820130
18Excessive salivation (HP:0003781)3.42052410
19Drooling (HP:0002307)3.42052410
20Pancreatic fibrosis (HP:0100732)3.40030490
21True hermaphroditism (HP:0010459)3.31991191
22Poor eye contact (HP:0000817)3.23468310
23Supranuclear gaze palsy (HP:0000605)3.22511729
24Molar tooth sign on MRI (HP:0002419)3.19851043
25Abnormality of midbrain morphology (HP:0002418)3.19851043
26Mutism (HP:0002300)3.18680169
27Amblyopia (HP:0000646)3.16298979
28Pancreatic cysts (HP:0001737)3.15188142
29Rhinitis (HP:0012384)3.13418936
30Limb dystonia (HP:0002451)3.04267131
31Ankle clonus (HP:0011448)3.03276845
32Action tremor (HP:0002345)2.88759359
33Epileptiform EEG discharges (HP:0011182)2.88334810
34Abnormality of the labia minora (HP:0012880)2.85920365
35Abnormality of the renal medulla (HP:0100957)2.83173783
36Absent speech (HP:0001344)2.83105467
37Impaired vibration sensation in the lower limbs (HP:0002166)2.80734619
38Abnormal social behavior (HP:0012433)2.80387479
39Impaired social interactions (HP:0000735)2.80387479
40Nephrogenic diabetes insipidus (HP:0009806)2.80024059
41Inability to walk (HP:0002540)2.79893524
42Truncal ataxia (HP:0002078)2.79118461
43Gaze-evoked nystagmus (HP:0000640)2.78915609
44Cerebral inclusion bodies (HP:0100314)2.76844909
45Papilledema (HP:0001085)2.75975340
46Abnormal eating behavior (HP:0100738)2.75508664
47EEG with generalized epileptiform discharges (HP:0011198)2.75230432
48Urinary bladder sphincter dysfunction (HP:0002839)2.74177706
49Progressive inability to walk (HP:0002505)2.69034417
50Polyphagia (HP:0002591)2.68058297
51Abnormality of the corticospinal tract (HP:0002492)2.66738431
52Genetic anticipation (HP:0003743)2.64304682
53Anxiety (HP:0000739)2.64246835
54Gait imbalance (HP:0002141)2.63872678
55Genital tract atresia (HP:0001827)2.62371963
56Termporal pattern (HP:0011008)2.61491527
57Insidious onset (HP:0003587)2.61491527
58Hypsarrhythmia (HP:0002521)2.60620629
59Amyotrophic lateral sclerosis (HP:0007354)2.59082250
60Dysdiadochokinesis (HP:0002075)2.58713978
61Depression (HP:0000716)2.58528425
62Neurofibrillary tangles (HP:0002185)2.56582754
63Vaginal atresia (HP:0000148)2.54963819
64Agitation (HP:0000713)2.46498132
65Hemiparesis (HP:0001269)2.44635789
66Dysmetria (HP:0001310)2.39561221
67Protruding tongue (HP:0010808)2.38634745
68Fetal akinesia sequence (HP:0001989)2.38026837
69Diplopia (HP:0000651)2.36553019
70Abnormality of binocular vision (HP:0011514)2.36553019
71Stereotypic behavior (HP:0000733)2.33255145
72Occipital encephalocele (HP:0002085)2.32065434
73Urinary urgency (HP:0000012)2.31267091
74Abnormality of salivation (HP:0100755)2.31147088
75Impaired smooth pursuit (HP:0007772)2.30151659
76Spastic gait (HP:0002064)2.29469880
77Retinal dysplasia (HP:0007973)2.28562564
78Aplasia/Hypoplasia of the brainstem (HP:0007362)2.26097305
79Hypoplasia of the brainstem (HP:0002365)2.26097305
80Scanning speech (HP:0002168)2.26059350
81Akinesia (HP:0002304)2.24374144
82Poor coordination (HP:0002370)2.24110603
83Inappropriate behavior (HP:0000719)2.23258154
84Postural instability (HP:0002172)2.21686543
85Chronic bronchitis (HP:0004469)2.20039033
86Torticollis (HP:0000473)2.19979167
87Cystic liver disease (HP:0006706)2.15753380
88Postaxial hand polydactyly (HP:0001162)2.15440308
89Blue irides (HP:0000635)2.12875978
90Bradykinesia (HP:0002067)2.11240938
91Pheochromocytoma (HP:0002666)2.10450150
92Abnormal ciliary motility (HP:0012262)2.08425313
93Megalencephaly (HP:0001355)2.06721482
94Septo-optic dysplasia (HP:0100842)2.05735496
95Hyperthyroidism (HP:0000836)2.02657081
96Aplasia/Hypoplasia of the tongue (HP:0010295)2.01909767
97Generalized myoclonic seizures (HP:0002123)2.01670587
98Sclerocornea (HP:0000647)2.01555982
99Optic nerve hypoplasia (HP:0000609)2.00097048
100Focal dystonia (HP:0004373)1.98919709
101Lower limb muscle weakness (HP:0007340)1.98694760
102Postaxial foot polydactyly (HP:0001830)1.97868879
103Oligodactyly (hands) (HP:0001180)1.96251213
104Specific learning disability (HP:0001328)1.95809603
105Lissencephaly (HP:0001339)1.95605894
106Exotropia (HP:0000577)1.95227655
107Tubular atrophy (HP:0000092)1.93779372
108Abnormality of the lower motor neuron (HP:0002366)1.91518530
109Abnormality of ocular smooth pursuit (HP:0000617)1.90351107
110Acute necrotizing encephalopathy (HP:0006965)1.89709734
111Obstructive sleep apnea (HP:0002870)1.89529075
112Congenital primary aphakia (HP:0007707)1.89078095
113Hepatoblastoma (HP:0002884)1.88256123
114Medial flaring of the eyebrow (HP:0010747)1.87037175
115Chronic hepatic failure (HP:0100626)1.86225618
116Hypoventilation (HP:0002791)1.85914032
117Abnormality of the renal cortex (HP:0011035)1.85858542
118Type II lissencephaly (HP:0007260)1.83874327
119Impaired vibratory sensation (HP:0002495)1.81238479
120Abnormal respiratory motile cilium physiology (HP:0012261)1.80916891
121Progressive macrocephaly (HP:0004481)1.80876671
122Failure to thrive in infancy (HP:0001531)1.80774712
123Dynein arm defect of respiratory motile cilia (HP:0012255)1.80271489
124Absent/shortened dynein arms (HP:0200106)1.80271489
125Neuroendocrine neoplasm (HP:0100634)1.79959723
126Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.78536214
127Degeneration of the lateral corticospinal tracts (HP:0002314)1.78536214
128Craniofacial dystonia (HP:0012179)1.78130842
129Bronchiectasis (HP:0002110)1.77068115
130Congenital hepatic fibrosis (HP:0002612)1.76861648
131Anencephaly (HP:0002323)1.75688469
132Status epilepticus (HP:0002133)1.74762355
133Generalized hypopigmentation of hair (HP:0011358)1.73257113
134Sporadic (HP:0003745)1.73076227
135Aplasia/Hypoplasia of the lens (HP:0008063)1.72883797
136Narrow forehead (HP:0000341)1.72828034
137Sleep apnea (HP:0010535)1.72290708
138Male pseudohermaphroditism (HP:0000037)1.71298013
139Abnormal rod and cone electroretinograms (HP:0008323)1.70820580
140Colon cancer (HP:0003003)1.70672577
141Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.68593309
142Supernumerary spleens (HP:0009799)1.67363658
143Acute encephalopathy (HP:0006846)1.64829498
144Poor suck (HP:0002033)1.63812138
145Abnormal drinking behavior (HP:0030082)1.63792184
146Polydipsia (HP:0001959)1.63792184
147Cerebral hypomyelination (HP:0006808)1.62041202
148Intestinal atresia (HP:0011100)1.58699613
149Methylmalonic acidemia (HP:0002912)1.57883487
150Increased hepatocellular lipid droplets (HP:0006565)1.56765350
151Aplasia/Hypoplasia of the tibia (HP:0005772)1.56222580
152Median cleft lip (HP:0000161)1.54826439
153Intention tremor (HP:0002080)1.54449387
154Gastrointestinal atresia (HP:0002589)1.54307042
155Broad foot (HP:0001769)1.54179486
156Bony spicule pigmentary retinopathy (HP:0007737)1.53859387
157Preaxial hand polydactyly (HP:0001177)1.52856318

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.02824000
2NTRK33.92498232
3EPHA43.63377417
4MAP3K93.40551470
5CASK3.20061908
6MAP3K43.18983522
7FRK2.83530237
8MAP2K72.78046482
9MINK12.64746311
10PINK12.30453663
11PNCK2.28675060
12NTRK22.28185037
13DAPK22.20154786
14MAPK131.98882125
15MAP3K121.96362301
16STK161.93142620
17PAK61.84990915
18PLK21.80324243
19BMPR1B1.80001705
20MAP2K41.77707348
21KSR11.73174694
22TRIM281.70143813
23MAP4K21.69993836
24SIK21.69768935
25MAPK151.56183242
26TNIK1.55764422
27NTRK11.54822299
28STK391.48604807
29KSR21.48144562
30WNK41.47952815
31CDK51.45955322
32DAPK11.43243366
33RIPK41.43176855
34STK38L1.39887315
35GRK51.33037511
36PHKG11.31002518
37PHKG21.31002518
38GRK11.29070330
39CDK191.28752930
40LATS21.21317176
41CAMKK11.20797692
42PRKCG1.20596400
43PRKD31.20257287
44UHMK11.15295739
45CSNK1G21.13042394
46PRPF4B1.12637265
47ARAF1.11165112
48CAMK2A1.04759565
49DYRK21.02023877
50FES0.99790249
51DYRK1A0.96284865
52ADRBK20.93858208
53MKNK20.92527608
54CAMKK20.91204690
55TYRO30.90094906
56PAK30.89164706
57NME10.87008533
58MAP3K20.86988751
59CDK180.86961721
60CDK140.86047427
61CAMK2B0.85597791
62CDK150.82417420
63ERBB30.81632037
64WNK30.81416058
65BMPR20.80716871
66LIMK10.78982654
67MARK20.78793590
68OXSR10.78182523
69INSRR0.77015474
70SIK30.74005966
71CCNB10.72588433
72EPHB20.72377287
73CDK11A0.71816663
74MST40.71812285
75CSNK1G30.70324237
76SGK2230.70236321
77SGK4940.70236321
78RET0.69835157
79STK110.69129611
80NUAK10.66388003
81PLK30.66273877
82BCR0.65699994
83PRKCE0.65079686
84RAF10.64270326
85CSNK1A1L0.63168193
86AKT30.63126685
87MAP3K60.62292473
88CAMK10.62132091
89TSSK60.61184898
90STK30.61157525
91CSNK1E0.61009364
92SGK20.60762915
93SGK10.60593398
94CDK30.60410002
95TLK10.60346759
96CAMK1G0.58859723
97STK380.57613365
98PRKCZ0.57565003
99WEE10.56568762
100PTK2B0.55701484
101FGR0.55446828
102TAOK10.55190013
103PRKACA0.54641601
104CSNK1A10.54576250
105PKN10.52041118
106MAPK120.48140042
107DMPK0.48032956
108GRK70.47022567
109FGFR20.46998219
110PIK3CA0.46493360
111PRKCH0.46034329
112FER0.44697897
113BRAF0.43998668
114CAMK2D0.43889262
115LMTK20.42203792
116RPS6KA20.42097479
117PRKCI0.41869533
118BCKDK0.40988349
119CSNK1D0.40491932
120CSNK1G10.39986766
121ERBB20.38510413
122FYN0.38477857
123RPS6KA30.37257786
124CAMK2G0.35950410
125ADRBK10.35824224
126ZAK0.35657646
127PRKACB0.34995809
128MAPK100.33502821
129SGK30.33279572
130MAP2K10.31815106
131MAP3K130.31624786
132PRKG10.31509228
133PDK10.30647636
134PRKCB0.29933869
135CDC42BPA0.29196756
136PDPK10.28764628

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.93372661
2Synaptic vesicle cycle_Homo sapiens_hsa047213.17335090
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.79013737
4Circadian entrainment_Homo sapiens_hsa047132.70248148
5Long-term potentiation_Homo sapiens_hsa047202.67606018
6GABAergic synapse_Homo sapiens_hsa047272.65714403
7Glutamatergic synapse_Homo sapiens_hsa047242.58665889
8Olfactory transduction_Homo sapiens_hsa047402.56481960
9Protein export_Homo sapiens_hsa030602.53761658
10Morphine addiction_Homo sapiens_hsa050322.51458960
11Amphetamine addiction_Homo sapiens_hsa050312.50740472
12Dopaminergic synapse_Homo sapiens_hsa047282.34406701
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.05341796
14Salivary secretion_Homo sapiens_hsa049702.04701515
15Insulin secretion_Homo sapiens_hsa049112.03084769
16Taste transduction_Homo sapiens_hsa047421.96942056
17Serotonergic synapse_Homo sapiens_hsa047261.96917889
18Cholinergic synapse_Homo sapiens_hsa047251.91833178
19Long-term depression_Homo sapiens_hsa047301.86602121
20Renin secretion_Homo sapiens_hsa049241.85425800
21Cocaine addiction_Homo sapiens_hsa050301.79114225
22Aldosterone synthesis and secretion_Homo sapiens_hsa049251.70209469
23Gastric acid secretion_Homo sapiens_hsa049711.69588806
24Collecting duct acid secretion_Homo sapiens_hsa049661.65786914
25Oxytocin signaling pathway_Homo sapiens_hsa049211.63078976
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.61845039
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.60353559
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.55773640
29Axon guidance_Homo sapiens_hsa043601.49393560
30Calcium signaling pathway_Homo sapiens_hsa040201.47604406
31Gap junction_Homo sapiens_hsa045401.46247466
32Butanoate metabolism_Homo sapiens_hsa006501.44851214
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.44352856
34GnRH signaling pathway_Homo sapiens_hsa049121.38957737
35Phototransduction_Homo sapiens_hsa047441.38661749
36Propanoate metabolism_Homo sapiens_hsa006401.36206785
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.24881216
38cAMP signaling pathway_Homo sapiens_hsa040241.21490678
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.20455230
40Estrogen signaling pathway_Homo sapiens_hsa049151.20370050
41Vibrio cholerae infection_Homo sapiens_hsa051101.16578413
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.16305331
43ErbB signaling pathway_Homo sapiens_hsa040121.12123180
44Melanogenesis_Homo sapiens_hsa049161.10375299
45Glioma_Homo sapiens_hsa052141.09966577
46Type II diabetes mellitus_Homo sapiens_hsa049301.09835227
47Cardiac muscle contraction_Homo sapiens_hsa042601.07331044
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.06825548
49cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04222813
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02887395
51Folate biosynthesis_Homo sapiens_hsa007901.01090987
52Phosphatidylinositol signaling system_Homo sapiens_hsa040700.97514923
53Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.93272868
54Hippo signaling pathway_Homo sapiens_hsa043900.92010414
55Hedgehog signaling pathway_Homo sapiens_hsa043400.91211926
56Vascular smooth muscle contraction_Homo sapiens_hsa042700.91147971
57Oocyte meiosis_Homo sapiens_hsa041140.88442963
58Basal cell carcinoma_Homo sapiens_hsa052170.87028136
59Linoleic acid metabolism_Homo sapiens_hsa005910.86953468
60beta-Alanine metabolism_Homo sapiens_hsa004100.86058655
61Alzheimers disease_Homo sapiens_hsa050100.84328364
62Nitrogen metabolism_Homo sapiens_hsa009100.83429572
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.79796655
64Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.78584566
65Regulation of autophagy_Homo sapiens_hsa041400.78497754
66Dorso-ventral axis formation_Homo sapiens_hsa043200.77318557
67Basal transcription factors_Homo sapiens_hsa030220.76417967
68Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73156513
69Oxidative phosphorylation_Homo sapiens_hsa001900.72678391
70Pancreatic secretion_Homo sapiens_hsa049720.71851257
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71386676
72MAPK signaling pathway_Homo sapiens_hsa040100.71162264
73Steroid biosynthesis_Homo sapiens_hsa001000.70818442
74Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70680562
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.70332372
76Choline metabolism in cancer_Homo sapiens_hsa052310.69809659
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.69092781
78Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68838360
79Thyroid hormone synthesis_Homo sapiens_hsa049180.68688934
80Ras signaling pathway_Homo sapiens_hsa040140.68232977
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.67737437
82Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67500526
83Peroxisome_Homo sapiens_hsa041460.65108115
84Alcoholism_Homo sapiens_hsa050340.64225928
85Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.63951574
86Dilated cardiomyopathy_Homo sapiens_hsa054140.63668885
87RNA degradation_Homo sapiens_hsa030180.63636163
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.63361134
89Ether lipid metabolism_Homo sapiens_hsa005650.63272431
90Neurotrophin signaling pathway_Homo sapiens_hsa047220.62413013
91Fatty acid elongation_Homo sapiens_hsa000620.61970439
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61645730
93Endometrial cancer_Homo sapiens_hsa052130.61558712
94Glucagon signaling pathway_Homo sapiens_hsa049220.60932918
95Primary bile acid biosynthesis_Homo sapiens_hsa001200.59914390
96Wnt signaling pathway_Homo sapiens_hsa043100.59586903
97VEGF signaling pathway_Homo sapiens_hsa043700.57043069
98Renal cell carcinoma_Homo sapiens_hsa052110.56980513
99Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.56525896
100Tryptophan metabolism_Homo sapiens_hsa003800.56097947
101Vitamin B6 metabolism_Homo sapiens_hsa007500.55748255
102Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.55267453
103Sphingolipid signaling pathway_Homo sapiens_hsa040710.53733192
104Parkinsons disease_Homo sapiens_hsa050120.53141535
105Ribosome_Homo sapiens_hsa030100.52587413
106Tight junction_Homo sapiens_hsa045300.52399264
107Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52296950
108Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.51698298
109Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51693679
110Rap1 signaling pathway_Homo sapiens_hsa040150.50752515
111Circadian rhythm_Homo sapiens_hsa047100.48626688
112Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48009430
113Colorectal cancer_Homo sapiens_hsa052100.47449570
114Arginine and proline metabolism_Homo sapiens_hsa003300.47245206
115Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.46469521
116Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.45917688
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.45615319
118Huntingtons disease_Homo sapiens_hsa050160.44837194
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43167340
120Insulin signaling pathway_Homo sapiens_hsa049100.42891365
121Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42292959
122Retinol metabolism_Homo sapiens_hsa008300.42145014
123RNA polymerase_Homo sapiens_hsa030200.41970003
124Mineral absorption_Homo sapiens_hsa049780.41788557
125Prion diseases_Homo sapiens_hsa050200.41603623
126Selenocompound metabolism_Homo sapiens_hsa004500.41094003
127Chemical carcinogenesis_Homo sapiens_hsa052040.41058129
128Type I diabetes mellitus_Homo sapiens_hsa049400.40855498
129Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40826544
130Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.39200599
131Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38558321
132mTOR signaling pathway_Homo sapiens_hsa041500.38440666
133Ovarian steroidogenesis_Homo sapiens_hsa049130.38404493
134SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37025669
135Inositol phosphate metabolism_Homo sapiens_hsa005620.35803057
136Longevity regulating pathway - mammal_Homo sapiens_hsa042110.34661231
137African trypanosomiasis_Homo sapiens_hsa051430.33576136
138Non-small cell lung cancer_Homo sapiens_hsa052230.33501879
139Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.32649483
140Endocytosis_Homo sapiens_hsa041440.31095947
141Melanoma_Homo sapiens_hsa052180.27962647
142Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.26357141

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