MAPKBP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.07365802
2locomotory exploration behavior (GO:0035641)4.35566333
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.15529162
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.09900101
5proline transport (GO:0015824)4.09616917
6layer formation in cerebral cortex (GO:0021819)3.94939871
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.80839436
8vocalization behavior (GO:0071625)3.63138273
9hemidesmosome assembly (GO:0031581)3.55830733
10establishment of nucleus localization (GO:0040023)3.50563064
11synaptic vesicle docking involved in exocytosis (GO:0016081)3.43640727
12glutamate secretion (GO:0014047)3.41973768
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.37601408
14regulation of glutamate receptor signaling pathway (GO:1900449)3.17699536
15dendritic spine morphogenesis (GO:0060997)3.13106073
16sodium ion export (GO:0071436)3.13078589
17exploration behavior (GO:0035640)3.11860367
18positive regulation of synapse maturation (GO:0090129)3.10670088
19regulation of synaptic vesicle exocytosis (GO:2000300)3.10395552
20regulation of synapse structural plasticity (GO:0051823)3.03083602
21polyketide metabolic process (GO:0030638)3.02402879
22doxorubicin metabolic process (GO:0044598)3.02402879
23daunorubicin metabolic process (GO:0044597)3.02402879
24synaptic vesicle exocytosis (GO:0016079)3.01120791
25regulation of NFAT protein import into nucleus (GO:0051532)2.98333979
26ventricular system development (GO:0021591)2.95399460
27protein localization to synapse (GO:0035418)2.94475030
28negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.85128413
29regulation of long-term neuronal synaptic plasticity (GO:0048169)2.85082668
30regulation of ARF GTPase activity (GO:0032312)2.84813044
31neurotransmitter secretion (GO:0007269)2.82583392
32cerebellar granule cell differentiation (GO:0021707)2.81184188
33regulation of cilium movement (GO:0003352)2.80365115
34semaphorin-plexin signaling pathway (GO:0071526)2.78745392
35protein targeting to Golgi (GO:0000042)2.78588287
36ionotropic glutamate receptor signaling pathway (GO:0035235)2.76873736
37cellular potassium ion homeostasis (GO:0030007)2.76536307
38regulation of neuronal synaptic plasticity (GO:0048168)2.75981682
39negative regulation of synaptic transmission, GABAergic (GO:0032229)2.75630058
40desmosome organization (GO:0002934)2.74714697
41establishment of protein localization to Golgi (GO:0072600)2.74118735
42neuronal ion channel clustering (GO:0045161)2.73928001
43regulation of clathrin-mediated endocytosis (GO:2000369)2.72790674
44regulation of synaptic vesicle transport (GO:1902803)2.71433883
45histone H4-K5 acetylation (GO:0043981)2.69843135
46histone H4-K8 acetylation (GO:0043982)2.69843135
47positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.68851402
48cytoskeletal anchoring at plasma membrane (GO:0007016)2.68176423
49axon extension (GO:0048675)2.65556986
50prepulse inhibition (GO:0060134)2.65480216
51L-amino acid import (GO:0043092)2.63509684
52activation of protein kinase A activity (GO:0034199)2.63007261
53positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.62958249
54dendrite morphogenesis (GO:0048813)2.61816572
55regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.60146065
56cell-substrate junction assembly (GO:0007044)2.59672755
57retrograde transport, vesicle recycling within Golgi (GO:0000301)2.59232050
58synaptic transmission, glutamatergic (GO:0035249)2.58182823
59amino acid import (GO:0043090)2.57330023
60response to auditory stimulus (GO:0010996)2.55765577
61G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.54922830
62postsynaptic membrane organization (GO:0001941)2.54552999
63auditory behavior (GO:0031223)2.54412122
64negative regulation of potassium ion transmembrane transport (GO:1901380)2.53715204
65innervation (GO:0060384)2.52936772
66cilium or flagellum-dependent cell motility (GO:0001539)2.52344205
67maintenance of protein location in nucleus (GO:0051457)2.51802116
68synaptic vesicle endocytosis (GO:0048488)2.51800996
69stress granule assembly (GO:0034063)2.51548720
70neuromuscular process controlling balance (GO:0050885)2.51364041
71piRNA metabolic process (GO:0034587)2.50343807
72microtubule severing (GO:0051013)2.48679286
73mitochondrion distribution (GO:0048311)2.48266689
74regulation of dendritic spine morphogenesis (GO:0061001)2.48154885
75myelination in peripheral nervous system (GO:0022011)2.44860142
76peripheral nervous system axon ensheathment (GO:0032292)2.44860142
77long-term memory (GO:0007616)2.44839347
78histone H4-K16 acetylation (GO:0043984)2.44667721
79glutamate receptor signaling pathway (GO:0007215)2.43866788
80neurotransmitter-gated ion channel clustering (GO:0072578)2.43773596
81cerebellar Purkinje cell differentiation (GO:0021702)2.43295028
82positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.43140596
83insulin-like growth factor receptor signaling pathway (GO:0048009)2.40386263
84cell differentiation in hindbrain (GO:0021533)2.39944147
85positive regulation of macrophage cytokine production (GO:0060907)2.39873651
86cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.38886759
87regulation of synaptic plasticity (GO:0048167)2.38184834
88neuron projection extension (GO:1990138)2.37837999
89pre-miRNA processing (GO:0031054)2.37173818
90cell migration in hindbrain (GO:0021535)2.36314940
91regulation of ARF protein signal transduction (GO:0032012)2.36089969
92cell communication by electrical coupling (GO:0010644)2.35425793
93ovulation cycle (GO:0042698)2.33596888
94regulation of microtubule-based movement (GO:0060632)2.32963183
95fusion of sperm to egg plasma membrane (GO:0007342)2.32764003
96regulation of mammary gland epithelial cell proliferation (GO:0033599)2.32664530
97axonal fasciculation (GO:0007413)2.32414432
98neuron-neuron synaptic transmission (GO:0007270)2.32358624
99mannose metabolic process (GO:0006013)2.31509691
100gamma-aminobutyric acid transport (GO:0015812)2.28767543
101regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.27863646
102membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.27735065
103vesicle transport along microtubule (GO:0047496)2.26882005
104negative regulation of inclusion body assembly (GO:0090084)2.26846387
105regulation of excitatory postsynaptic membrane potential (GO:0060079)2.26771796
106regulation of response to osmotic stress (GO:0047484)2.26752135
107nerve growth factor signaling pathway (GO:0038180)2.26204907
108central nervous system projection neuron axonogenesis (GO:0021952)2.26161882
109neuron remodeling (GO:0016322)2.26047096
110NLS-bearing protein import into nucleus (GO:0006607)2.25762768
111positive regulation of axon extension (GO:0045773)2.25520963
112dopamine receptor signaling pathway (GO:0007212)2.25114778
113clathrin coat assembly (GO:0048268)2.24816044
114regulation of synapse maturation (GO:0090128)2.24631274
115positive regulation of synaptic transmission, GABAergic (GO:0032230)2.23864046
116striatum development (GO:0021756)2.22650336
117negative regulation of Ras protein signal transduction (GO:0046580)2.22390109
118positive regulation of dendrite development (GO:1900006)2.21943241
119membrane depolarization during action potential (GO:0086010)2.21810242
120peptidyl-threonine phosphorylation (GO:0018107)2.20686171
121negative regulation of Rho protein signal transduction (GO:0035024)2.19144934
122regulation of postsynaptic membrane potential (GO:0060078)2.18979531
123dendritic spine organization (GO:0097061)2.18445028
124neuron cell-cell adhesion (GO:0007158)2.18235286
125neurotransmitter transport (GO:0006836)2.17120202
126focal adhesion assembly (GO:0048041)2.16939490
127cell-substrate adherens junction assembly (GO:0007045)2.16939490
128adherens junction assembly (GO:0034333)2.16516638
129negative regulation of fatty acid transport (GO:2000192)2.15627308
130regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.14772229
131gamma-aminobutyric acid signaling pathway (GO:0007214)2.14634289
132atrioventricular valve morphogenesis (GO:0003181)2.14011851
133positive regulation of dendritic spine development (GO:0060999)2.13478331
134cell-cell junction maintenance (GO:0045217)2.12703114
135cardiac muscle hypertrophy in response to stress (GO:0014898)2.12512131
136muscle hypertrophy in response to stress (GO:0003299)2.12512131
137cardiac muscle adaptation (GO:0014887)2.12512131
138negative regulation of small GTPase mediated signal transduction (GO:0051058)2.11973989
139endothelial cell chemotaxis (GO:0035767)2.11311055
140regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.10720636
141positive regulation of dendrite morphogenesis (GO:0050775)2.10135015
142regulation of axon extension involved in axon guidance (GO:0048841)2.09113435
143establishment of skin barrier (GO:0061436)2.08130792
144potassium ion import (GO:0010107)2.07448999
145protein localization to endosome (GO:0036010)2.07000863
146regulation of vesicle fusion (GO:0031338)2.06248338
147central nervous system myelination (GO:0022010)2.05922780
148axon ensheathment in central nervous system (GO:0032291)2.05922780
149negative regulation of catenin import into nucleus (GO:0035414)2.04457133
150regulation of neurotransmitter secretion (GO:0046928)2.03646101
151positive regulation of membrane potential (GO:0045838)2.03265050
152urinary tract smooth muscle contraction (GO:0014848)2.03205545
153negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.00588768

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.95489372
2EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.42839922
3ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.29849054
4STAT6_21828071_ChIP-Seq_BEAS2B_Human2.07567463
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.06619288
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.04931740
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.04931740
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.03002736
9RARB_27405468_Chip-Seq_BRAIN_Mouse2.02988018
10LXR_22292898_ChIP-Seq_THP-1_Human2.00932062
11SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.96241493
12IKZF1_21737484_ChIP-ChIP_HCT116_Human1.95275327
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.94761608
14RNF2_27304074_Chip-Seq_ESCs_Mouse1.94157872
15SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.93713964
16DROSHA_22980978_ChIP-Seq_HELA_Human1.88045965
17JARID2_20064375_ChIP-Seq_MESCs_Mouse1.86993464
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.82837031
19MTF2_20144788_ChIP-Seq_MESCs_Mouse1.81943468
20KDM2B_26808549_Chip-Seq_K562_Human1.81735700
21REST_21632747_ChIP-Seq_MESCs_Mouse1.77710123
22JARID2_20075857_ChIP-Seq_MESCs_Mouse1.74026149
23SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.70196974
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.67915238
25WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.64988851
26ZFP281_18757296_ChIP-ChIP_E14_Mouse1.63753854
27RARG_19884340_ChIP-ChIP_MEFs_Mouse1.62726264
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.61383837
29VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.60822625
30EZH2_27304074_Chip-Seq_ESCs_Mouse1.59906097
31EZH2_27294783_Chip-Seq_ESCs_Mouse1.59294579
32ZFP281_27345836_Chip-Seq_ESCs_Mouse1.54544828
33KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.52400775
34SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.49542695
35TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.48926900
36KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.48075954
37KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.48075954
38KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.48075954
39TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.47945573
40KDM2B_26808549_Chip-Seq_SUP-B15_Human1.45270450
41MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.44016163
42* CTCF_27219007_Chip-Seq_Bcells_Human1.42197516
43BP1_19119308_ChIP-ChIP_Hs578T_Human1.41165098
44WT1_25993318_ChIP-Seq_PODOCYTE_Human1.38992491
45ZNF217_24962896_ChIP-Seq_MCF-7_Human1.38976622
46ELK3_25401928_ChIP-Seq_HUVEC_Human1.37949033
47RING1B_27294783_Chip-Seq_NPCs_Mouse1.36137749
48UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.36112143
49TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.34580744
50REST_18959480_ChIP-ChIP_MESCs_Mouse1.34066001
51AHR_22903824_ChIP-Seq_MCF-7_Human1.31306520
52* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.30522313
53* TP53_23651856_ChIP-Seq_MEFs_Mouse1.28643025
54GBX2_23144817_ChIP-Seq_PC3_Human1.28034947
55CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.27079986
56TP63_17297297_ChIP-ChIP_HaCaT_Human1.26174874
57* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.22924033
58BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.22923399
59ERG_21242973_ChIP-ChIP_JURKAT_Human1.22842662
60ELK4_26923725_Chip-Seq_MESODERM_Mouse1.22655590
61RING1B_27294783_Chip-Seq_ESCs_Mouse1.21861340
62EED_16625203_ChIP-ChIP_MESCs_Mouse1.21475222
63SOX9_24532713_ChIP-Seq_HFSC_Mouse1.20473076
64ARNT_22903824_ChIP-Seq_MCF-7_Human1.19398124
65TP63_22573176_ChIP-Seq_HFKS_Human1.19184359
66CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.18454391
67AR_21572438_ChIP-Seq_LNCaP_Human1.18078693
68DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.17878722
69RACK7_27058665_Chip-Seq_MCF-7_Human1.17542463
70TP53_22127205_ChIP-Seq_IMR90_Human1.16915842
71AR_19668381_ChIP-Seq_PC3_Human1.16648050
72P68_20966046_ChIP-Seq_HELA_Human1.16627416
73SMAD3_21741376_ChIP-Seq_HESCs_Human1.13930706
74CREB1_26743006_Chip-Seq_LNCaP_Human1.13334285
75RNF2_27304074_Chip-Seq_NSC_Mouse1.12699123
76ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.11913173
77ESR2_21235772_ChIP-Seq_MCF-7_Human1.11881182
78SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.11228553
79RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.10952742
80EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.09928040
81KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.09139763
82SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.08233923
83CDX2_19796622_ChIP-Seq_MESCs_Mouse1.06329249
84FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.06110989
85P63_26484246_Chip-Seq_KERATINOCYTES_Human1.06104150
86GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04559430
87SMAD4_21799915_ChIP-Seq_A2780_Human1.03430931
88P300_27058665_Chip-Seq_ZR-75-30cells_Human1.02769995
89SMAD_19615063_ChIP-ChIP_OVARY_Human1.01753537
90* SOX2_21211035_ChIP-Seq_LN229_Gbm1.01692958
91SMC4_20622854_ChIP-Seq_HELA_Human1.01267777
92NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.01145497
93KDM2B_26808549_Chip-Seq_DND41_Human1.01057854
94NFIB_24661679_ChIP-Seq_LUNG_Mouse1.00845068
95* SA1_27219007_Chip-Seq_ERYTHROID_Human0.99223329
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.98737563
97CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.98087495
98YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97874466
99KDM2B_26808549_Chip-Seq_JURKAT_Human0.97191332
100CTCF_27219007_Chip-Seq_ERYTHROID_Human0.97093582
101ESR1_21235772_ChIP-Seq_MCF-7_Human0.96991705
102MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96890610
103RUNX1_27514584_Chip-Seq_MCF-7_Human0.96883707
104NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.96206918
105GATA2_21666600_ChIP-Seq_HMVEC_Human0.95742358
106RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.95632248
107TCF7_22412390_ChIP-Seq_EML_Mouse0.95424729
108NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.95324841
109TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.95318646
110ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.95178172
111FOXO3_23340844_ChIP-Seq_DLD1_Human0.95078210
112SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94686433
113DNAJC2_21179169_ChIP-ChIP_NT2_Human0.94653834
114PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.94357797
115STAT3_23295773_ChIP-Seq_U87_Human0.94262230
116TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94228706
117P53_22127205_ChIP-Seq_FIBROBLAST_Human0.94093050
118SMAD3_21741376_ChIP-Seq_ESCs_Human0.92633463
119SMAD4_21741376_ChIP-Seq_HESCs_Human0.92314464
120OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.91846392
121VDR_21846776_ChIP-Seq_THP-1_Human0.91546557
122TET1_21490601_ChIP-Seq_MESCs_Mouse0.90358996
123CTNNB1_20460455_ChIP-Seq_HCT116_Human0.90079619
124GATA1_26923725_Chip-Seq_HPCs_Mouse0.89611397
125ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.89328388
126POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.88980082
127TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88980082
128ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.88971752
129TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88559960
130ISL1_27105846_Chip-Seq_CPCs_Mouse0.88244573
131RXR_22108803_ChIP-Seq_LS180_Human0.87641797
132KLF5_25053715_ChIP-Seq_YYC3_Human0.86379897
133TP53_20018659_ChIP-ChIP_R1E_Mouse0.85630228
134* NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.84705726
135TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.83450419
136* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82983686
137OCT4_19829295_ChIP-Seq_ESCs_Human0.81898550

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.10163305
2MP0004858_abnormal_nervous_system3.66855782
3MP0005409_darkened_coat_color2.91604532
4MP0000569_abnormal_digit_pigmentation2.91513342
5MP0003635_abnormal_synaptic_transmissio2.90150395
6MP0002254_reproductive_system_inflammat2.89646870
7MP0004270_analgesia2.64760427
8MP0000579_abnormal_nail_morphology2.61242001
9MP0009046_muscle_twitch2.42365243
10MP0002063_abnormal_learning/memory/cond2.38420073
11MP0008961_abnormal_basal_metabolism2.36986325
12MP0005275_abnormal_skin_tensile2.31895098
13MP0003705_abnormal_hypodermis_morpholog2.27090149
14MP0005410_abnormal_fertilization2.09601939
15MP0005499_abnormal_olfactory_system1.96375680
16MP0005394_taste/olfaction_phenotype1.96375680
17MP0003122_maternal_imprinting1.93755249
18MP0002572_abnormal_emotion/affect_behav1.92704963
19MP0009745_abnormal_behavioral_response1.92587273
20MP0003880_abnormal_central_pattern1.92059930
21MP0005423_abnormal_somatic_nervous1.89974496
22MP0003283_abnormal_digestive_organ1.85227584
23MP0009780_abnormal_chondrocyte_physiolo1.83603537
24MP0008438_abnormal_cutaneous_collagen1.78952387
25MP0002064_seizures1.78777876
26MP0002653_abnormal_ependyma_morphology1.78092730
27MP0005623_abnormal_meninges_morphology1.76930336
28MP0001486_abnormal_startle_reflex1.74525727
29MP0010234_abnormal_vibrissa_follicle1.74428010
30MP0002909_abnormal_adrenal_gland1.70981201
31MP0003279_aneurysm1.69742317
32MP0001502_abnormal_circadian_rhythm1.68584718
33MP0003890_abnormal_embryonic-extraembry1.68056426
34MP0001501_abnormal_sleep_pattern1.67733871
35MP0002249_abnormal_larynx_morphology1.57770895
36MP0003566_abnormal_cell_adhesion1.56753360
37MP0003172_abnormal_lysosome_physiology1.56554261
38MP0003787_abnormal_imprinting1.56269993
39MP0004381_abnormal_hair_follicle1.55692284
40MP0002734_abnormal_mechanical_nocicepti1.55528162
41MP0002822_catalepsy1.54867346
42MP0000778_abnormal_nervous_system1.53338677
43MP0002184_abnormal_innervation1.50242026
44MP0003045_fibrosis1.49880845
45MP0001958_emphysema1.48609106
46MP0004264_abnormal_extraembryonic_tissu1.48028802
47MP0000955_abnormal_spinal_cord1.42840225
48MP0004811_abnormal_neuron_physiology1.38954626
49MP0002089_abnormal_postnatal_growth/wei1.36741533
50MP0002735_abnormal_chemical_nociception1.32897626
51MP0005503_abnormal_tendon_morphology1.31622548
52MP0003453_abnormal_keratinocyte_physiol1.28307361
53MP0001440_abnormal_grooming_behavior1.27390357
54MP0005171_absent_coat_pigmentation1.26948881
55MP0000013_abnormal_adipose_tissue1.24630803
56MP0010352_gastrointestinal_tract_polyps1.23846810
57MP0001849_ear_inflammation1.23406759
58MP0005670_abnormal_white_adipose1.21405229
59MP0002272_abnormal_nervous_system1.20743124
60MP0004885_abnormal_endolymph1.18748742
61MP0002557_abnormal_social/conspecific_i1.18740801
62MP0000733_abnormal_muscle_development1.16894783
63MP0004130_abnormal_muscle_cell1.16718698
64MP0001968_abnormal_touch/_nociception1.14447994
65MP0002733_abnormal_thermal_nociception1.14302627
66MP0001984_abnormal_olfaction1.12515953
67MP0003121_genomic_imprinting1.12175546
68MP0002060_abnormal_skin_morphology1.12059998
69MP0000604_amyloidosis1.11457252
70MP0000003_abnormal_adipose_tissue1.10294239
71MP0003879_abnormal_hair_cell1.09900818
72MP0008569_lethality_at_weaning1.09770386
73MP0005257_abnormal_intraocular_pressure1.09523452
74MP0004947_skin_inflammation1.09446684
75MP0002332_abnormal_exercise_endurance1.08154974
76MP0002882_abnormal_neuron_morphology1.07401912
77MP0000920_abnormal_myelination1.06554294
78MP0005248_abnormal_Harderian_gland1.04178140
79MP0000467_abnormal_esophagus_morphology1.03939876
80MP0001348_abnormal_lacrimal_gland1.03845302
81MP0003329_amyloid_beta_deposits1.02986498
82MP0003698_abnormal_male_reproductive0.99349747
83MP0005646_abnormal_pituitary_gland0.99132888
84MP0002067_abnormal_sensory_capabilities0.97817077
85MP0000762_abnormal_tongue_morphology0.96956721
86MP0005023_abnormal_wound_healing0.96929527
87MP0006292_abnormal_olfactory_placode0.96487159
88MP0001299_abnormal_eye_distance/0.95791772
89MP0005167_abnormal_blood-brain_barrier0.95232040
90MP0010678_abnormal_skin_adnexa0.93719883
91MP0005386_behavior/neurological_phenoty0.93366369
92MP0004924_abnormal_behavior0.93366369
93MP0009840_abnormal_foam_cell0.92709504
94MP0004272_abnormal_basement_membrane0.92509412
95MP0003011_delayed_dark_adaptation0.92267410
96MP0005076_abnormal_cell_differentiation0.92184113
97MP0002152_abnormal_brain_morphology0.91623145
98MP0009384_cardiac_valve_regurgitation0.90859460
99MP0000751_myopathy0.90605421
100MP0010368_abnormal_lymphatic_system0.90518139
101MP0003690_abnormal_glial_cell0.89760482
102MP0002234_abnormal_pharynx_morphology0.89229528
103MP0004134_abnormal_chest_morphology0.88366477
104MP0003632_abnormal_nervous_system0.88149747
105MP0001970_abnormal_pain_threshold0.87461794
106MP0000678_abnormal_parathyroid_gland0.87271049
107MP0003631_nervous_system_phenotype0.87191755
108MP0003861_abnormal_nervous_system0.86789123
109MP0002233_abnormal_nose_morphology0.85467670
110MP0003091_abnormal_cell_migration0.82273034
111MP0000428_abnormal_craniofacial_morphol0.81443213
112MP0000383_abnormal_hair_follicle0.80784082
113MP0000767_abnormal_smooth_muscle0.79919751
114MP0000015_abnormal_ear_pigmentation0.78993166
115MP0001216_abnormal_epidermal_layer0.78936962
116MP0002295_abnormal_pulmonary_circulatio0.78600663
117MP0000566_synostosis0.78595266
118MP0003935_abnormal_craniofacial_develop0.78503400
119MP0004085_abnormal_heartbeat0.76598377
120MP0003938_abnormal_ear_development0.76289964
121MP0003119_abnormal_digestive_system0.76138914
122MP0000631_abnormal_neuroendocrine_gland0.76058772
123MP0010771_integument_phenotype0.75945898
124MP0003633_abnormal_nervous_system0.75727665
125MP0002066_abnormal_motor_capabilities/c0.75642209
126MP0004145_abnormal_muscle_electrophysio0.75483354
127MP0005187_abnormal_penis_morphology0.74225834
128MP0001177_atelectasis0.73921132
129MP0003137_abnormal_impulse_conducting0.73362951
130MP0002090_abnormal_vision0.72402285
131MP0008872_abnormal_physiological_respon0.71135954
132MP0004510_myositis0.69895144
133MP0005595_abnormal_vascular_smooth0.69556908
134MP0002896_abnormal_bone_mineralization0.69132806
135MP0008770_decreased_survivor_rate0.68404543
136MP0002081_perinatal_lethality0.68070495
137MP0003755_abnormal_palate_morphology0.67261491
138MP0003123_paternal_imprinting0.64408368
139MP0003634_abnormal_glial_cell0.64248841
140MP0003075_altered_response_to0.63070205
141MP0000534_abnormal_ureter_morphology0.63053544
142MP0003183_abnormal_peptide_metabolism0.61860914
143MP0002116_abnormal_craniofacial_bone0.60317454
144MP0002127_abnormal_cardiovascular_syste0.58238150
145MP0002796_impaired_skin_barrier0.57951232
146MP0003942_abnormal_urinary_system0.57915789

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the lower motor neuron (HP:0002366)4.76179233
2Bilateral microphthalmos (HP:0007633)3.77933773
3Amyotrophic lateral sclerosis (HP:0007354)3.40314387
4Hepatoblastoma (HP:0002884)3.36376754
5Focal seizures (HP:0007359)3.33328464
6Diplopia (HP:0000651)3.29782796
7Abnormality of binocular vision (HP:0011514)3.29782796
8Neurofibrillary tangles (HP:0002185)3.00644866
9Atrophic scars (HP:0001075)3.00264820
10Difficulty running (HP:0009046)2.85329948
11Epileptic encephalopathy (HP:0200134)2.82065993
12Broad face (HP:0000283)2.72480376
13Focal motor seizures (HP:0011153)2.70839947
14Visual hallucinations (HP:0002367)2.70693890
15Febrile seizures (HP:0002373)2.69316428
16Abnormality of nail color (HP:0100643)2.65496542
17Thick nail (HP:0001805)2.65331086
18Neoplasm of the heart (HP:0100544)2.63878747
19Myokymia (HP:0002411)2.62083237
20Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.61037201
21Cerebral inclusion bodies (HP:0100314)2.53397183
22Hemiparesis (HP:0001269)2.50161225
23Macroorchidism (HP:0000053)2.47715360
24Hand muscle atrophy (HP:0009130)2.44093194
25Upper limb amyotrophy (HP:0009129)2.43186589
26Distal upper limb amyotrophy (HP:0007149)2.43186589
27Truncal ataxia (HP:0002078)2.39687153
28Hemiplegia (HP:0002301)2.36990167
29Astrocytoma (HP:0009592)2.35870352
30Abnormality of the astrocytes (HP:0100707)2.35870352
31Dynein arm defect of respiratory motile cilia (HP:0012255)2.34936031
32Absent/shortened dynein arms (HP:0200106)2.34936031
33Action tremor (HP:0002345)2.26148607
34Amblyopia (HP:0000646)2.25075751
35Renal duplication (HP:0000075)2.17295137
36Absent frontal sinuses (HP:0002688)2.16064812
37Stereotypic behavior (HP:0000733)2.15121714
38Turricephaly (HP:0000262)2.13503735
39Hyperventilation (HP:0002883)2.13011644
40Difficulty climbing stairs (HP:0003551)2.12553966
41Progressive cerebellar ataxia (HP:0002073)2.12231950
42Protrusio acetabuli (HP:0003179)2.11887438
43Ankyloglossia (HP:0010296)2.11094265
44Genetic anticipation (HP:0003743)2.11046834
45Fragile skin (HP:0001030)2.09880739
46Heterotopia (HP:0002282)2.08903231
47Lower limb amyotrophy (HP:0007210)2.05009439
48Bronchomalacia (HP:0002780)2.03436452
49Bladder diverticulum (HP:0000015)2.02668614
50Drooling (HP:0002307)2.02313652
51Excessive salivation (HP:0003781)2.02313652
52Atonic seizures (HP:0010819)2.02100303
53Supranuclear gaze palsy (HP:0000605)2.00841973
54Ankle clonus (HP:0011448)1.98492663
55Thin bony cortex (HP:0002753)1.97500809
56Abnormality of ocular smooth pursuit (HP:0000617)1.96462662
57Generalized hypotonia (HP:0001290)1.96034819
58Dialeptic seizures (HP:0011146)1.95887926
59Ependymoma (HP:0002888)1.95604938
60Hypoventilation (HP:0002791)1.93436111
61Natal tooth (HP:0000695)1.92510592
62Arterial tortuosity (HP:0005116)1.92187547
63Aplasia involving bones of the extremities (HP:0009825)1.91502455
64Aplasia involving bones of the upper limbs (HP:0009823)1.91502455
65Aplasia of the phalanges of the hand (HP:0009802)1.91502455
66Spastic gait (HP:0002064)1.91246697
67Ulnar bowing (HP:0003031)1.87661528
68Onion bulb formation (HP:0003383)1.87335147
69Aortic aneurysm (HP:0004942)1.86406210
70Resting tremor (HP:0002322)1.85965155
71Plantar hyperkeratosis (HP:0007556)1.85944635
72Open mouth (HP:0000194)1.84836550
73Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.83827904
74Short 4th metacarpal (HP:0010044)1.83827904
75Vascular tortuosity (HP:0004948)1.83816311
76Absence seizures (HP:0002121)1.83809750
77Urinary bladder sphincter dysfunction (HP:0002839)1.83566933
78Generalized tonic-clonic seizures (HP:0002069)1.83341620
79Dysmetria (HP:0001310)1.83109200
80Cervical subluxation (HP:0003308)1.82492008
81Horizontal nystagmus (HP:0000666)1.80885823
82Bifid tongue (HP:0010297)1.80639888
83Achilles tendon contracture (HP:0001771)1.80619434
84Apathy (HP:0000741)1.80508409
85Neuronal loss in central nervous system (HP:0002529)1.79977917
86Sleep apnea (HP:0010535)1.79607083
87Abnormality of the salivary glands (HP:0010286)1.78642165
88Spinal canal stenosis (HP:0003416)1.78619771
89Inappropriate behavior (HP:0000719)1.77818878
90Lip pit (HP:0100267)1.76911970
91Lymphangioma (HP:0100764)1.76437681
92Nasal polyposis (HP:0100582)1.76291380
93Advanced eruption of teeth (HP:0006288)1.75310864
94Laryngomalacia (HP:0001601)1.75237129
95Dysmetric saccades (HP:0000641)1.74883634
96Premature rupture of membranes (HP:0001788)1.74632444
97Absent speech (HP:0001344)1.73635500
98Status epilepticus (HP:0002133)1.73571589
99Insomnia (HP:0100785)1.73184143
100Shallow orbits (HP:0000586)1.72466477
101Tetraplegia (HP:0002445)1.72434466
102Pointed chin (HP:0000307)1.71988858
103Subacute progressive viral hepatitis (HP:0006572)1.71773685
104Hypochromic microcytic anemia (HP:0004840)1.70897159
105Fragile nails (HP:0001808)1.70481394
106Mildly elevated creatine phosphokinase (HP:0008180)1.70148127
107Spastic tetraparesis (HP:0001285)1.69995027
108Intellectual disability, profound (HP:0002187)1.69803690
109Dysdiadochokinesis (HP:0002075)1.69801210
110Hypopigmentation of the fundus (HP:0007894)1.69353563
111Vitreoretinal degeneration (HP:0000655)1.69220450
112Cerebral aneurysm (HP:0004944)1.67155088
113Impaired smooth pursuit (HP:0007772)1.66692705
114Increased connective tissue (HP:0009025)1.66483527
115Broad metatarsal (HP:0001783)1.66391834
116Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.66233548
117Aneurysm (HP:0002617)1.65858326
118Hyperacusis (HP:0010780)1.65556821
119Abnormal respiratory motile cilium physiology (HP:0012261)1.65177325
120Annular pancreas (HP:0001734)1.64589391
121Alopecia of scalp (HP:0002293)1.63871954
122Increased variability in muscle fiber diameter (HP:0003557)1.62727993
123Depression (HP:0000716)1.62529478
124Abnormality of chromosome segregation (HP:0002916)1.61608620
125Diminished motivation (HP:0000745)1.61121581
126Stridor (HP:0010307)1.61092165
127Overgrowth (HP:0001548)1.61047099
128Bowel incontinence (HP:0002607)1.60371575
129Neonatal short-limb short stature (HP:0008921)1.60098728
130Abnormality of the pubic bones (HP:0003172)1.59726040
131Abnormality of the musculature of the hand (HP:0001421)1.59465340
132Neoplasm of striated muscle (HP:0009728)1.59442368
133Hypoplasia of dental enamel (HP:0006297)1.59034947
134Impaired social interactions (HP:0000735)1.58751901
135Abnormal social behavior (HP:0012433)1.58751901
136Milia (HP:0001056)1.58437984
137Abnormality of the corticospinal tract (HP:0002492)1.58406914
138Akinesia (HP:0002304)1.57842846
139Gaze-evoked nystagmus (HP:0000640)1.57056157
140Leiomyosarcoma (HP:0100243)1.55929832
141Uterine leiomyosarcoma (HP:0002891)1.55929832
142Ocular albinism (HP:0001107)1.55824239
143Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.55765420
144Abnormality of the distal phalanx of the thumb (HP:0009617)1.55693603
145Spinal rigidity (HP:0003306)1.55433821
146Abnormality of oral frenula (HP:0000190)1.55311421
147Poor eye contact (HP:0000817)1.54693236
148Obstructive sleep apnea (HP:0002870)1.54339240
149Rapidly progressive (HP:0003678)1.54293211
150Oligodontia (HP:0000677)1.54214571
151Hamartoma of the eye (HP:0010568)1.52727051
152EMG: neuropathic changes (HP:0003445)1.52586490
153Papilledema (HP:0001085)1.52274192
154Large earlobe (HP:0009748)1.52219565
155Aqueductal stenosis (HP:0002410)1.52001257
156Supernumerary nipples (HP:0002558)1.51740029
157Lower limb muscle weakness (HP:0007340)1.51532704
158Mutism (HP:0002300)1.51016528
159Papillary thyroid carcinoma (HP:0002895)1.50681610
160Onycholysis (HP:0001806)1.50461201
161Glioma (HP:0009733)1.50317373
162Postural instability (HP:0002172)1.49827694
163Genu recurvatum (HP:0002816)1.49425183
164Narrow palate (HP:0000189)1.49059175
165Wormian bones (HP:0002645)1.48556876

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.06971066
2MAP3K93.46512507
3TYRO32.89546279
4MARK12.85148943
5GRK52.73784438
6NTRK32.52935734
7PRKD32.46946703
8EPHA42.16704710
9ERN12.14648183
10NTRK22.05304047
11DAPK21.94503363
12RIPK11.91315022
13PAK61.85451157
14MAP3K101.83462371
15PRKD21.77973358
16NTRK11.70937803
17TAOK11.67150696
18STK381.65847630
19WNK11.64908752
20EEF2K1.64588566
21MAP3K41.62587837
22LATS21.60935552
23SIK21.57765718
24KSR21.53747620
25MINK11.50380575
26MAP2K41.49756247
27KSR11.29825620
28CAMKK11.29492551
29TRIB31.28875802
30CAMK1G1.27323777
31PDK41.26578719
32PDK31.26578719
33MARK21.25885573
34SGK4941.25857113
35SGK2231.25857113
36PDGFRA1.20425470
37ICK1.14099004
38MOS1.13273481
39PKN21.12712048
40GRK61.07644808
41DDR21.06692330
42ALK1.04061152
43FGFR31.00726394
44ARAF1.00296499
45UHMK10.99927866
46MAPK70.96504740
47LATS10.95193272
48PINK10.94951759
49CDK50.94498169
50EPHB10.93957257
51CAMK40.93553653
52PDPK10.93424361
53PDK20.92711825
54PTK2B0.91772710
55MAP3K60.90197272
56CAMK1D0.89501649
57RIPK40.86800824
58TTN0.86325752
59SMG10.86100168
60RET0.85043770
61FGFR20.83693742
62MAP3K70.83043868
63CSF1R0.82268565
64MET0.82159495
65MAPK150.79883573
66MAP3K20.79527888
67PHKG10.78189845
68PHKG20.78189845
69MST1R0.77500274
70GRK10.76801217
71BRD40.75032857
72DMPK0.72783585
73STK110.71963635
74CDC42BPA0.70028628
75PDGFRB0.69665337
76NEK60.69328694
77PRKCH0.68997709
78PAK30.65971213
79LMTK20.63223976
80MATK0.62662089
81MTOR0.62217661
82TNK20.62124702
83MAP3K10.61935743
84HIPK20.61117564
85AKT30.59421054
86EPHA30.59294838
87TRPM70.56673147
88PRKCG0.56415534
89DAPK10.56286089
90TGFBR20.56268099
91EPHA20.55460681
92FGFR40.55445930
93PLK20.55425450
94RPS6KC10.54260210
95RPS6KL10.54260210
96PDK10.53878846
97MAP3K110.53752740
98ERBB30.53411108
99SGK30.53153581
100MAP2K70.52944516
101PAK20.52915261
102ADRBK20.52873949
103CASK0.52691944
104PKN10.51177099
105MAPK110.50955575
106CAMK2B0.50523191
107SIK10.49778524
108CAMK10.49708317
109PRPF4B0.49554762
110MAP3K130.49340755
111SGK10.48971056
112RPS6KA30.48581560
113GRK70.48542736
114PTK20.47996574
115JAK10.47967650
116BMX0.47695808
117PRKD10.47110808
118FER0.46911019
119RPS6KA60.46543855
120MAPK130.46428217
121MAPK100.46044288
122ERBB20.45404179
123DYRK1A0.45295946
124PRKAA10.45266776
125MAPK120.45195100
126PTK60.42564837
127CDK90.42440804
128ROCK10.40527584
129RPS6KA20.39984512
130CDK180.39214667
131CDK150.38453276
132MAPK80.38182454
133PRKCZ0.38145353
134SGK20.36854064
135ADRBK10.36099022
136DYRK1B0.35306431
137TAOK20.33401330

Predicted pathways (KEGG)

RankGene SetZ-score
1Long-term potentiation_Homo sapiens_hsa047201.91420536
2Nicotine addiction_Homo sapiens_hsa050331.87619380
3Synaptic vesicle cycle_Homo sapiens_hsa047211.86036135
4Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.84431562
5Glutamatergic synapse_Homo sapiens_hsa047241.83649273
6Olfactory transduction_Homo sapiens_hsa047401.82510627
7Circadian entrainment_Homo sapiens_hsa047131.79627034
8GABAergic synapse_Homo sapiens_hsa047271.73127347
9Dorso-ventral axis formation_Homo sapiens_hsa043201.72542634
10Salivary secretion_Homo sapiens_hsa049701.53543015
11Amphetamine addiction_Homo sapiens_hsa050311.52845290
12Morphine addiction_Homo sapiens_hsa050321.51639005
13Renin secretion_Homo sapiens_hsa049241.48258774
14Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.48222056
15Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.43885590
16GnRH signaling pathway_Homo sapiens_hsa049121.42566470
17Dopaminergic synapse_Homo sapiens_hsa047281.42244106
18Oxytocin signaling pathway_Homo sapiens_hsa049211.41803057
19Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.40557963
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.40553477
21Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.36569140
22Gastric acid secretion_Homo sapiens_hsa049711.35826529
23mTOR signaling pathway_Homo sapiens_hsa041501.34716610
24Phosphatidylinositol signaling system_Homo sapiens_hsa040701.33135128
25Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.30288125
26Type II diabetes mellitus_Homo sapiens_hsa049301.29806484
27Cholinergic synapse_Homo sapiens_hsa047251.29732022
28Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.24125670
29Insulin secretion_Homo sapiens_hsa049111.23661589
30Glioma_Homo sapiens_hsa052141.23344085
31Thyroid hormone signaling pathway_Homo sapiens_hsa049191.22712377
32ECM-receptor interaction_Homo sapiens_hsa045121.21750281
33Taste transduction_Homo sapiens_hsa047421.21656090
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.21114738
35cAMP signaling pathway_Homo sapiens_hsa040241.20959969
36Long-term depression_Homo sapiens_hsa047301.19145103
37Calcium signaling pathway_Homo sapiens_hsa040201.17780078
38Estrogen signaling pathway_Homo sapiens_hsa049151.17573372
39Phospholipase D signaling pathway_Homo sapiens_hsa040721.16993929
40Axon guidance_Homo sapiens_hsa043601.16799880
41ErbB signaling pathway_Homo sapiens_hsa040121.12823078
42Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.10410591
43Cocaine addiction_Homo sapiens_hsa050301.08166019
44VEGF signaling pathway_Homo sapiens_hsa043701.04218554
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01523307
46Dilated cardiomyopathy_Homo sapiens_hsa054141.00946937
47Serotonergic synapse_Homo sapiens_hsa047261.00418455
48Neurotrophin signaling pathway_Homo sapiens_hsa047220.97875544
49Ovarian steroidogenesis_Homo sapiens_hsa049130.96846690
50Melanogenesis_Homo sapiens_hsa049160.96194036
51Choline metabolism in cancer_Homo sapiens_hsa052310.95997863
52Gap junction_Homo sapiens_hsa045400.94403155
53Longevity regulating pathway - mammal_Homo sapiens_hsa042110.94027903
54Endometrial cancer_Homo sapiens_hsa052130.93274874
55Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.92672262
56Inositol phosphate metabolism_Homo sapiens_hsa005620.92433910
57Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.89644055
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.89225866
59Rap1 signaling pathway_Homo sapiens_hsa040150.84491043
60MAPK signaling pathway_Homo sapiens_hsa040100.84141514
61Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.81813366
62Non-small cell lung cancer_Homo sapiens_hsa052230.80983157
63Glycosaminoglycan degradation_Homo sapiens_hsa005310.79785131
64Proteoglycans in cancer_Homo sapiens_hsa052050.79661151
65Carbohydrate digestion and absorption_Homo sapiens_hsa049730.79365575
66Hedgehog signaling pathway_Homo sapiens_hsa043400.77924898
67Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.77866734
68Central carbon metabolism in cancer_Homo sapiens_hsa052300.75766595
69Basal cell carcinoma_Homo sapiens_hsa052170.74914118
70Acute myeloid leukemia_Homo sapiens_hsa052210.74743534
71Prion diseases_Homo sapiens_hsa050200.74532570
72Colorectal cancer_Homo sapiens_hsa052100.74394062
73Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73909178
74Prolactin signaling pathway_Homo sapiens_hsa049170.73333890
75Wnt signaling pathway_Homo sapiens_hsa043100.73079161
76Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73042277
77Focal adhesion_Homo sapiens_hsa045100.72891911
78Fatty acid biosynthesis_Homo sapiens_hsa000610.71409845
79Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.69840866
80Hippo signaling pathway_Homo sapiens_hsa043900.69788000
81Ras signaling pathway_Homo sapiens_hsa040140.68870300
82Alcoholism_Homo sapiens_hsa050340.68697268
83Other glycan degradation_Homo sapiens_hsa005110.68228741
84Oocyte meiosis_Homo sapiens_hsa041140.67525546
85Glucagon signaling pathway_Homo sapiens_hsa049220.67522365
86Circadian rhythm_Homo sapiens_hsa047100.67207798
87Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.66996395
88Protein digestion and absorption_Homo sapiens_hsa049740.65770378
89Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.65716235
90Vitamin B6 metabolism_Homo sapiens_hsa007500.65178692
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.64880123
92Pancreatic cancer_Homo sapiens_hsa052120.64684877
93B cell receptor signaling pathway_Homo sapiens_hsa046620.64603860
94Renal cell carcinoma_Homo sapiens_hsa052110.64566129
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.63936863
96AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.63554411
97Amoebiasis_Homo sapiens_hsa051460.62086190
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.61115076
99Chronic myeloid leukemia_Homo sapiens_hsa052200.60553474
100Sphingolipid signaling pathway_Homo sapiens_hsa040710.59951359
101AMPK signaling pathway_Homo sapiens_hsa041520.59789098
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59500020
103Endocytosis_Homo sapiens_hsa041440.59349186
104Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.58711931
105Insulin signaling pathway_Homo sapiens_hsa049100.58293591
106Thyroid hormone synthesis_Homo sapiens_hsa049180.57753764
107Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57501330
108Notch signaling pathway_Homo sapiens_hsa043300.57428366
109Phototransduction_Homo sapiens_hsa047440.57229687
110TNF signaling pathway_Homo sapiens_hsa046680.56264517
111Melanoma_Homo sapiens_hsa052180.56020077
112Bile secretion_Homo sapiens_hsa049760.55244932
113Insulin resistance_Homo sapiens_hsa049310.54795188
114T cell receptor signaling pathway_Homo sapiens_hsa046600.54686766
115Adherens junction_Homo sapiens_hsa045200.53863858
116MicroRNAs in cancer_Homo sapiens_hsa052060.53792964

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