MARK4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1layer formation in cerebral cortex (GO:0021819)4.92772861
2regulation of short-term neuronal synaptic plasticity (GO:0048172)4.81665334
3synaptic vesicle maturation (GO:0016188)4.80412131
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.65917192
5locomotory exploration behavior (GO:0035641)4.60593771
6vocalization behavior (GO:0071625)4.50257410
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.27242129
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.25484945
9synaptic vesicle exocytosis (GO:0016079)4.20624423
10sodium ion export (GO:0071436)4.03553530
11dendritic spine morphogenesis (GO:0060997)3.99698102
12glutamate secretion (GO:0014047)3.88456217
13protein localization to synapse (GO:0035418)3.87337404
14cell migration in hindbrain (GO:0021535)3.86445747
15regulation of glutamate receptor signaling pathway (GO:1900449)3.83162107
16exploration behavior (GO:0035640)3.72518416
17positive regulation of synapse maturation (GO:0090129)3.67190803
18regulation of synaptic vesicle exocytosis (GO:2000300)3.58735881
19planar cell polarity pathway involved in neural tube closure (GO:0090179)3.57510932
20regulation of synapse structural plasticity (GO:0051823)3.54479391
21regulation of long-term neuronal synaptic plasticity (GO:0048169)3.51990127
22ionotropic glutamate receptor signaling pathway (GO:0035235)3.48213561
23neuron cell-cell adhesion (GO:0007158)3.42695755
24synaptic vesicle docking involved in exocytosis (GO:0016081)3.42488245
25regulation of neuronal synaptic plasticity (GO:0048168)3.42129076
26cellular potassium ion homeostasis (GO:0030007)3.41805178
27dendrite morphogenesis (GO:0048813)3.41795692
28cytoskeletal anchoring at plasma membrane (GO:0007016)3.38175747
29neurotransmitter secretion (GO:0007269)3.31379387
30neuron recognition (GO:0008038)3.25338489
31cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.20563816
32neuromuscular process controlling balance (GO:0050885)3.19412685
33regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.18149602
34G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.17583727
35gamma-aminobutyric acid transport (GO:0015812)3.15580423
36cell communication by electrical coupling (GO:0010644)3.14048395
37proline transport (GO:0015824)3.13146957
38synaptic vesicle endocytosis (GO:0048488)3.11012813
39regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.10314568
40glutamate receptor signaling pathway (GO:0007215)3.09205499
41regulation of synaptic vesicle transport (GO:1902803)3.07913695
42regulation of dendritic spine morphogenesis (GO:0061001)3.07434957
43dopamine receptor signaling pathway (GO:0007212)3.04562439
44axonal fasciculation (GO:0007413)3.04067209
45cell-cell junction maintenance (GO:0045217)3.01328776
46regulation of clathrin-mediated endocytosis (GO:2000369)2.96494256
47regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.95096084
48negative regulation of microtubule polymerization (GO:0031115)2.92200099
49lymph vessel development (GO:0001945)2.89635170
50positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.89526405
51mating behavior (GO:0007617)2.87689531
52synaptic transmission, glutamatergic (GO:0035249)2.87554523
53regulation of ARF GTPase activity (GO:0032312)2.84676352
54activation of protein kinase A activity (GO:0034199)2.84589944
55cerebellar Purkinje cell differentiation (GO:0021702)2.82103831
56central nervous system projection neuron axonogenesis (GO:0021952)2.80368081
57positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.79528625
58axon extension (GO:0048675)2.79512229
59plasma membrane repair (GO:0001778)2.75731814
60cell communication involved in cardiac conduction (GO:0086065)2.75532654
61regulation of ARF protein signal transduction (GO:0032012)2.75459955
62cochlea morphogenesis (GO:0090103)2.74013879
63neuronal action potential propagation (GO:0019227)2.73746203
64establishment of nucleus localization (GO:0040023)2.69217997
65regulation of excitatory postsynaptic membrane potential (GO:0060079)2.69202444
66cerebellar granule cell differentiation (GO:0021707)2.68003076
67cerebellar Purkinje cell layer development (GO:0021680)2.67871588
68innervation (GO:0060384)2.67451991
69tooth mineralization (GO:0034505)2.66118024
70regulation of postsynaptic membrane potential (GO:0060078)2.65813808
71membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.65229168
72neuron-neuron synaptic transmission (GO:0007270)2.65218347
73adherens junction assembly (GO:0034333)2.65089057
74mitochondrion transport along microtubule (GO:0047497)2.64965825
75establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.64965825
76positive regulation of dendritic spine development (GO:0060999)2.64910171
77positive regulation of fibroblast migration (GO:0010763)2.64871223
78regulation of synaptic plasticity (GO:0048167)2.64142704
79convergent extension (GO:0060026)2.64096419
80regulation of dendritic spine development (GO:0060998)2.63848708
81neuronal ion channel clustering (GO:0045161)2.63700534
82negative regulation of catenin import into nucleus (GO:0035414)2.62756224
83response to parathyroid hormone (GO:0071107)2.62014415
84long-term memory (GO:0007616)2.61648483
85dendritic spine organization (GO:0097061)2.61505464
86regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.61495504
87positive regulation of membrane potential (GO:0045838)2.61416443
88semaphorin-plexin signaling pathway (GO:0071526)2.60791880
89cell junction maintenance (GO:0034331)2.59985324
90regulation of synapse maturation (GO:0090128)2.59366309
91cranial nerve morphogenesis (GO:0021602)2.58445191
92neuromuscular process controlling posture (GO:0050884)2.58277992
93positive regulation of dendritic spine morphogenesis (GO:0061003)2.57771244
94adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.56897758
95neurotransmitter transport (GO:0006836)2.55301800
96Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.55241033
97postsynaptic membrane organization (GO:0001941)2.54092943
98regulation of glycogen (starch) synthase activity (GO:2000465)2.53968046
99regulation of vesicle fusion (GO:0031338)2.53959229
100social behavior (GO:0035176)2.53680101
101intraspecies interaction between organisms (GO:0051703)2.53680101
102protein localization to endosome (GO:0036010)2.53647706
103synapse organization (GO:0050808)2.53057648
104axon cargo transport (GO:0008088)2.52329918
105regulation of NFAT protein import into nucleus (GO:0051532)2.51433905
106neurotransmitter-gated ion channel clustering (GO:0072578)2.51358486
107organelle transport along microtubule (GO:0072384)2.51002020
108potassium ion homeostasis (GO:0055075)2.50810940
109focal adhesion assembly (GO:0048041)2.50620588
110cell-substrate adherens junction assembly (GO:0007045)2.50620588
111negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.50018685
112axon extension involved in axon guidance (GO:0048846)2.49892720
113neuron projection extension involved in neuron projection guidance (GO:1902284)2.49892720
114regulation of early endosome to late endosome transport (GO:2000641)2.49501148
115positive regulation of synaptic transmission, GABAergic (GO:0032230)2.48811264
116camera-type eye morphogenesis (GO:0048593)2.48309339
117synapse assembly (GO:0007416)2.47921292
118neuron projection extension (GO:1990138)2.47396114
119neuromuscular process (GO:0050905)2.46827026
120cellular response to monoamine stimulus (GO:0071868)2.44600162
121cellular response to catecholamine stimulus (GO:0071870)2.44600162
122positive regulation of axon extension (GO:0045773)2.43574638
123establishment of mitochondrion localization (GO:0051654)2.42864122
124positive regulation of dendrite development (GO:1900006)2.42768328
125clathrin coat assembly (GO:0048268)2.42582032
126peripheral nervous system axon ensheathment (GO:0032292)2.41787279
127myelination in peripheral nervous system (GO:0022011)2.41787279
128regulation of voltage-gated calcium channel activity (GO:1901385)2.41073399
129signal complex assembly (GO:0007172)2.40532339
130outflow tract septum morphogenesis (GO:0003148)2.39752445
131protein targeting to plasma membrane (GO:0072661)2.38699900
132regulation of establishment of planar polarity (GO:0090175)2.35728480
133respiratory system process (GO:0003016)2.35647853
134negative regulation of fatty acid transport (GO:2000192)2.34799033
135sarcoplasmic reticulum calcium ion transport (GO:0070296)2.33115871
136regulation of respiratory system process (GO:0044065)2.32852396
137cardiac myofibril assembly (GO:0055003)2.30133831
138regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.27533124
139vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.26429788
140atrioventricular valve morphogenesis (GO:0003181)2.25753783
141regulation of axon extension involved in axon guidance (GO:0048841)2.25173770
142bone trabecula formation (GO:0060346)2.23995604
143developmental cell growth (GO:0048588)2.20679786
144positive regulation of neurotransmitter transport (GO:0051590)2.20323147
145endothelial cell chemotaxis (GO:0035767)2.18406385
146auditory behavior (GO:0031223)2.18320825

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.30566167
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.78782624
3JARID2_20064375_ChIP-Seq_MESCs_Mouse2.77140490
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.69122200
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.61545156
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.58353079
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.58353079
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.54477121
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.43436758
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.37104093
11IKZF1_21737484_ChIP-ChIP_HCT116_Human2.35235599
12MTF2_20144788_ChIP-Seq_MESCs_Mouse2.31098964
13EZH2_27304074_Chip-Seq_ESCs_Mouse2.29705253
14DROSHA_22980978_ChIP-Seq_HELA_Human2.28639300
15SUZ12_27294783_Chip-Seq_ESCs_Mouse2.24036777
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.22184500
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21352968
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.18918789
19RARB_27405468_Chip-Seq_BRAIN_Mouse2.18753324
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.18556457
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.16992854
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.15465876
23KDM2B_26808549_Chip-Seq_K562_Human2.11129485
24* ZFP281_18757296_ChIP-ChIP_E14_Mouse2.08204202
25ERG_21242973_ChIP-ChIP_JURKAT_Human2.06069972
26RARG_19884340_ChIP-ChIP_MEFs_Mouse2.03798494
27KDM2B_26808549_Chip-Seq_SUP-B15_Human1.99265010
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.95791664
29REST_21632747_ChIP-Seq_MESCs_Mouse1.93335251
30* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.87804596
31EED_16625203_ChIP-ChIP_MESCs_Mouse1.87033457
32TP63_17297297_ChIP-ChIP_HaCaT_Human1.86890970
33TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.70472913
34ZFP281_27345836_Chip-Seq_ESCs_Mouse1.69888602
35REST_18959480_ChIP-ChIP_MESCs_Mouse1.64671218
36KDM2B_26808549_Chip-Seq_DND41_Human1.63961184
37DNAJC2_21179169_ChIP-ChIP_NT2_Human1.61731507
38SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.60695983
39LXR_22292898_ChIP-Seq_THP-1_Human1.59318816
40RING1B_27294783_Chip-Seq_ESCs_Mouse1.58761669
41AR_21572438_ChIP-Seq_LNCaP_Human1.56566756
42* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.56075737
43TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.52611365
44RING1B_27294783_Chip-Seq_NPCs_Mouse1.52538497
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.51877037
46ZNF263_19887448_ChIP-Seq_K562_Human1.48022540
47P68_20966046_ChIP-Seq_HELA_Human1.44024487
48ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.43531314
49EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.43441876
50KDM2B_26808549_Chip-Seq_JURKAT_Human1.41993716
51TP53_20018659_ChIP-ChIP_R1E_Mouse1.39672486
52TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36368460
53SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.36151001
54VDR_21846776_ChIP-Seq_THP-1_Human1.35456216
55WT1_25993318_ChIP-Seq_PODOCYTE_Human1.34594401
56TET1_21451524_ChIP-Seq_MESCs_Mouse1.34533013
57CTCF_27219007_Chip-Seq_Bcells_Human1.33190572
58THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.32836919
59CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.32438361
60CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.30757916
61SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.30113220
62PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.28131444
63GBX2_23144817_ChIP-Seq_PC3_Human1.24353735
64ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.24193056
65* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20379236
66TP53_22127205_ChIP-Seq_IMR90_Human1.19905119
67SRY_22984422_ChIP-ChIP_TESTIS_Rat1.18317956
68RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.18012151
69DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.17907091
70STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.17425087
71MYC_22102868_ChIP-Seq_BL_Human1.16690944
72TRIM28_21343339_ChIP-Seq_HEK293_Human1.15726259
73RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.14673531
74CREB1_26743006_Chip-Seq_LNCaP_Human1.12874590
75P300_27058665_Chip-Seq_ZR-75-30cells_Human1.12835031
76ESR2_21235772_ChIP-Seq_MCF-7_Human1.12333357
77KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.11626404
78NFIB_24661679_ChIP-Seq_LUNG_Mouse1.08841221
79TET1_21490601_ChIP-Seq_MESCs_Mouse1.07645944
80OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.07512416
81ZNF217_24962896_ChIP-Seq_MCF-7_Human1.07260541
82* TP53_23651856_ChIP-Seq_MEFs_Mouse1.06508682
83AHR_22903824_ChIP-Seq_MCF-7_Human1.05521502
84RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.04882056
85UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.02444585
86* RACK7_27058665_Chip-Seq_MCF-7_Human1.02197082
87NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.01666391
88KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.01130372
89CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.00937293
90* AR_19668381_ChIP-Seq_PC3_Human0.98643309
91ZNF274_21170338_ChIP-Seq_K562_Hela0.98598466
92* MYC_27129775_Chip-Seq_CORNEA_Mouse0.98141356
93TCF7_22412390_ChIP-Seq_EML_Mouse0.98074378
94VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.97919298
95PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.97102564
96SMC3_22415368_ChIP-Seq_MEFs_Mouse0.97052159
97SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.96625515
98KLF4_19829295_ChIP-Seq_ESCs_Human0.94070325
99SMC4_20622854_ChIP-Seq_HELA_Human0.93003697
100SMAD3_21741376_ChIP-Seq_HESCs_Human0.92093492
101NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91964864
102ARNT_22903824_ChIP-Seq_MCF-7_Human0.91631365
103ELK3_25401928_ChIP-Seq_HUVEC_Human0.90767538
104ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.90469192
105RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.90464964
106ISL1_27105846_Chip-Seq_CPCs_Mouse0.90309210
107CDX2_19796622_ChIP-Seq_MESCs_Mouse0.90176147
108* SOX9_24532713_ChIP-Seq_HFSC_Mouse0.88007316
109SOX2_21211035_ChIP-Seq_LN229_Gbm0.87925614
110RUNX1_27514584_Chip-Seq_MCF-7_Human0.87441183
111SMAD4_21741376_ChIP-Seq_HESCs_Human0.86615335
112OCT4_19829295_ChIP-Seq_ESCs_Human0.86470344
113CBX2_27304074_Chip-Seq_ESCs_Mouse0.86262389
114MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.86086128
115SA1_27219007_Chip-Seq_ERYTHROID_Human0.86023913
116TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.85432946
117CTCF_27219007_Chip-Seq_ERYTHROID_Human0.82236657
118CTBP1_25329375_ChIP-Seq_LNCAP_Human0.81175275
119* TP63_22573176_ChIP-Seq_HFKS_Human0.80881521
120ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.80491359

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.89406372
2MP0003635_abnormal_synaptic_transmissio3.49241435
3MP0003880_abnormal_central_pattern3.26750691
4MP0004270_analgesia3.23167132
5MP0004858_abnormal_nervous_system2.82987859
6MP0005409_darkened_coat_color2.81372405
7MP0002063_abnormal_learning/memory/cond2.80310225
8MP0002064_seizures2.44584915
9MP0009745_abnormal_behavioral_response2.42457650
10MP0009046_muscle_twitch2.30929734
11MP0002249_abnormal_larynx_morphology2.29756195
12MP0005423_abnormal_somatic_nervous2.28977766
13MP0002572_abnormal_emotion/affect_behav2.20087321
14MP0005623_abnormal_meninges_morphology2.14383441
15MP0000751_myopathy2.11098146
16MP0010030_abnormal_orbit_morphology2.10821780
17MP0000778_abnormal_nervous_system2.07528600
18MP0003329_amyloid_beta_deposits2.04860296
19MP0001968_abnormal_touch/_nociception2.02487266
20MP0001440_abnormal_grooming_behavior1.97460438
21MP0009780_abnormal_chondrocyte_physiolo1.93289229
22MP0002734_abnormal_mechanical_nocicepti1.91298472
23MP0004130_abnormal_muscle_cell1.80362075
24MP0001486_abnormal_startle_reflex1.79769092
25MP0002733_abnormal_thermal_nociception1.79298533
26MP0002184_abnormal_innervation1.78235825
27MP0004885_abnormal_endolymph1.77199857
28MP0002272_abnormal_nervous_system1.70438308
29MP0004811_abnormal_neuron_physiology1.68816441
30MP0003942_abnormal_urinary_system1.66117146
31MP0003705_abnormal_hypodermis_morpholog1.64999195
32MP0003279_aneurysm1.63686467
33MP0009053_abnormal_anal_canal1.58516818
34MP0000955_abnormal_spinal_cord1.57624816
35MP0001970_abnormal_pain_threshold1.57205159
36MP0003123_paternal_imprinting1.55191381
37MP0002796_impaired_skin_barrier1.55052982
38MP0008569_lethality_at_weaning1.51568195
39MP0005257_abnormal_intraocular_pressure1.51220280
40MP0008961_abnormal_basal_metabolism1.50145939
41MP0000678_abnormal_parathyroid_gland1.48933576
42MP0001501_abnormal_sleep_pattern1.48751625
43MP0000049_abnormal_middle_ear1.46467928
44MP0002909_abnormal_adrenal_gland1.44701316
45MP0005670_abnormal_white_adipose1.42902400
46MP0002735_abnormal_chemical_nociception1.41662271
47MP0010368_abnormal_lymphatic_system1.41350026
48MP0003879_abnormal_hair_cell1.40165483
49MP0000733_abnormal_muscle_development1.39473221
50MP0002067_abnormal_sensory_capabilities1.38982187
51MP0000566_synostosis1.38896143
52MP0002882_abnormal_neuron_morphology1.34973207
53MP0002736_abnormal_nociception_after1.32974612
54MP0000750_abnormal_muscle_regeneration1.31470563
55MP0002557_abnormal_social/conspecific_i1.31011108
56MP0000579_abnormal_nail_morphology1.26164656
57MP0000537_abnormal_urethra_morphology1.24992644
58MP0010234_abnormal_vibrissa_follicle1.24774699
59MP0000003_abnormal_adipose_tissue1.22568714
60MP0005386_behavior/neurological_phenoty1.21813598
61MP0004924_abnormal_behavior1.21813598
62MP0009379_abnormal_foot_pigmentation1.21069249
63MP0008438_abnormal_cutaneous_collagen1.20017623
64MP0004145_abnormal_muscle_electrophysio1.19817889
65MP0004233_abnormal_muscle_weight1.19364254
66MP0002152_abnormal_brain_morphology1.17226244
67MP0002066_abnormal_motor_capabilities/c1.17135481
68MP0006276_abnormal_autonomic_nervous1.16935390
69MP0003303_peritoneal_inflammation1.15500898
70MP0001849_ear_inflammation1.10765042
71MP0003283_abnormal_digestive_organ1.09635099
72MP0009250_abnormal_appendicular_skeleto1.07973759
73MP0000767_abnormal_smooth_muscle1.05460699
74MP0003122_maternal_imprinting1.05157527
75MP0005187_abnormal_penis_morphology1.05081036
76MP0005375_adipose_tissue_phenotype1.04720970
77MP0004510_myositis1.04707092
78MP0002234_abnormal_pharynx_morphology1.03902136
79MP0002106_abnormal_muscle_physiology1.02304547
80MP0002932_abnormal_joint_morphology1.02044725
81MP0002090_abnormal_vision1.01007284
82MP0001346_abnormal_lacrimal_gland1.00489692
83MP0003634_abnormal_glial_cell0.99225390
84MP0002116_abnormal_craniofacial_bone0.98734162
85MP0003633_abnormal_nervous_system0.98367755
86MP0009384_cardiac_valve_regurgitation0.98333589
87MP0001879_abnormal_lymphatic_vessel0.96792004
88MP0005508_abnormal_skeleton_morphology0.96310533
89MP0004085_abnormal_heartbeat0.95343942
90MP0010630_abnormal_cardiac_muscle0.93650531
91MP0003861_abnormal_nervous_system0.93526163
92MP0003137_abnormal_impulse_conducting0.93447843
93MP0001299_abnormal_eye_distance/0.93354900
94MP0005369_muscle_phenotype0.93317924
95MP0001348_abnormal_lacrimal_gland0.92596086
96MP0005394_taste/olfaction_phenotype0.92101152
97MP0005499_abnormal_olfactory_system0.92101152
98MP0005248_abnormal_Harderian_gland0.90375952
99MP0004185_abnormal_adipocyte_glucose0.89957023
100MP0000747_muscle_weakness0.89064810
101MP0003045_fibrosis0.88647005
102MP0003119_abnormal_digestive_system0.87954901
103MP0002837_dystrophic_cardiac_calcinosis0.87805807
104MP0001188_hyperpigmentation0.87607826
105MP0005076_abnormal_cell_differentiation0.87561237
106MP0002108_abnormal_muscle_morphology0.86549812
107MP0003385_abnormal_body_wall0.86104369
108MP0001958_emphysema0.85412426
109MP0005167_abnormal_blood-brain_barrier0.84181063
110MP0003631_nervous_system_phenotype0.83434976
111MP0008874_decreased_physiological_sensi0.80554457
112MP0005646_abnormal_pituitary_gland0.79648745
113MP0005503_abnormal_tendon_morphology0.79225662
114MP0005275_abnormal_skin_tensile0.78577459
115MP0004036_abnormal_muscle_relaxation0.77990938
116MP0004087_abnormal_muscle_fiber0.77393600
117MP0009278_abnormal_bone_marrow0.76825130
118MP0003566_abnormal_cell_adhesion0.76694670
119MP0001502_abnormal_circadian_rhythm0.76101066
120MP0004742_abnormal_vestibular_system0.75701507
121MP0000604_amyloidosis0.74807030
122MP0002822_catalepsy0.73098872
123MP0000569_abnormal_digit_pigmentation0.69156308
124MP0000467_abnormal_esophagus_morphology0.68996800
125MP0002653_abnormal_ependyma_morphology0.68170593
126MP0000534_abnormal_ureter_morphology0.68110685
127MP0000759_abnormal_skeletal_muscle0.67732402
128MP0002089_abnormal_postnatal_growth/wei0.67493988
129MP0004084_abnormal_cardiac_muscle0.67420278
130MP0005501_abnormal_skin_physiology0.65555921
131MP0004272_abnormal_basement_membrane0.65412920
132MP0002752_abnormal_somatic_nervous0.65050330
133MP0002081_perinatal_lethality0.65040323
134MP0001340_abnormal_eyelid_morphology0.65013100
135MP0003632_abnormal_nervous_system0.64476967
136MP0008770_decreased_survivor_rate0.64404578
137MP0002069_abnormal_eating/drinking_beha0.63983852
138MP0000762_abnormal_tongue_morphology0.63913558
139MP0004215_abnormal_myocardial_fiber0.62147973
140MP0006138_congestive_heart_failure0.61443311
141MP0004484_altered_response_of0.61178528

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)4.47107785
2Visual hallucinations (HP:0002367)4.30544989
3Focal motor seizures (HP:0011153)4.04220359
4Focal seizures (HP:0007359)3.88210389
5Supranuclear gaze palsy (HP:0000605)3.60385857
6Type 1 muscle fiber predominance (HP:0003803)3.25862932
7Progressive cerebellar ataxia (HP:0002073)3.22619626
8Protrusio acetabuli (HP:0003179)3.21363762
9Abnormality of the lower motor neuron (HP:0002366)3.07466701
10Cerebral inclusion bodies (HP:0100314)3.01223917
11Abnormality of the aortic arch (HP:0012303)2.98561915
12Ankle clonus (HP:0011448)2.93742116
13Genetic anticipation (HP:0003743)2.77917841
14Absence seizures (HP:0002121)2.74062147
15Obstructive sleep apnea (HP:0002870)2.69682751
16Epileptic encephalopathy (HP:0200134)2.69449884
17Mutism (HP:0002300)2.68806827
18Action tremor (HP:0002345)2.65103234
19Broad metatarsal (HP:0001783)2.64595737
20Generalized tonic-clonic seizures (HP:0002069)2.63924095
21Termporal pattern (HP:0011008)2.62632334
22Insidious onset (HP:0003587)2.62632334
23Neurofibrillary tangles (HP:0002185)2.59001359
24Amblyopia (HP:0000646)2.55836432
25Rapidly progressive (HP:0003678)2.52983750
26Round ear (HP:0100830)2.52099208
27Urinary bladder sphincter dysfunction (HP:0002839)2.51878307
28Upper limb amyotrophy (HP:0009129)2.48710804
29Distal upper limb amyotrophy (HP:0007149)2.48710804
30Insomnia (HP:0100785)2.46102631
31Shallow orbits (HP:0000586)2.45605863
32Atonic seizures (HP:0010819)2.44664494
33Achilles tendon contracture (HP:0001771)2.42600274
34Sudden death (HP:0001699)2.41968373
35Dialeptic seizures (HP:0011146)2.39855142
36Depression (HP:0000716)2.35134579
37Lymphangioma (HP:0100764)2.32803196
38Myopathic facies (HP:0002058)2.32772270
39Hemiparesis (HP:0001269)2.32554249
40Annular pancreas (HP:0001734)2.31258906
41Bladder diverticulum (HP:0000015)2.29823158
42Megalencephaly (HP:0001355)2.29426497
43Muscle fiber splitting (HP:0003555)2.29007969
44Neoplasm of the heart (HP:0100544)2.28536267
45Hyperthyroidism (HP:0000836)2.28094081
46Lower limb amyotrophy (HP:0007210)2.27462230
47Ventricular fibrillation (HP:0001663)2.26132318
48Diplopia (HP:0000651)2.25859847
49Abnormality of binocular vision (HP:0011514)2.25859847
50Hand muscle atrophy (HP:0009130)2.25080790
51Distal lower limb amyotrophy (HP:0008944)2.24979890
52Hemiplegia (HP:0002301)2.24533675
53Amyotrophic lateral sclerosis (HP:0007354)2.23624306
54Spinal rigidity (HP:0003306)2.23297258
55Increased variability in muscle fiber diameter (HP:0003557)2.22328188
56Bronchomalacia (HP:0002780)2.20773177
57Thin ribs (HP:0000883)2.19125507
58Hyporeflexia of lower limbs (HP:0002600)2.18953612
59Difficulty running (HP:0009046)2.17428850
60Premature rupture of membranes (HP:0001788)2.16140549
61Pointed chin (HP:0000307)2.12274933
62Apathy (HP:0000741)2.11582191
63Peritonitis (HP:0002586)2.11215693
64Disproportionate tall stature (HP:0001519)2.10549450
65Dysmetric saccades (HP:0000641)2.10244297
66Coronal craniosynostosis (HP:0004440)2.09692038
67Abnormality of the Achilles tendon (HP:0005109)2.09333745
68Hyperacusis (HP:0010780)2.09091897
69Dysdiadochokinesis (HP:0002075)2.06687322
70Ulnar bowing (HP:0003031)2.05326923
71Cerebral aneurysm (HP:0004944)2.04363118
72Urinary urgency (HP:0000012)2.04262683
73Renal duplication (HP:0000075)2.03907052
74Truncus arteriosus (HP:0001660)2.03857210
75Abnormal social behavior (HP:0012433)2.03281715
76Impaired social interactions (HP:0000735)2.03281715
77Impaired vibration sensation in the lower limbs (HP:0002166)2.03233523
78Broad-based gait (HP:0002136)2.03070158
79Mitral regurgitation (HP:0001653)2.02543584
80Febrile seizures (HP:0002373)2.02414775
81Fragile nails (HP:0001808)2.01195393
82Mildly elevated creatine phosphokinase (HP:0008180)2.01080120
83Neuronal loss in central nervous system (HP:0002529)1.99519092
84Abnormality of the corticospinal tract (HP:0002492)1.98829521
85Poor eye contact (HP:0000817)1.96001678
86Distal lower limb muscle weakness (HP:0009053)1.93773158
87Sleep apnea (HP:0010535)1.93513586
88Fragile skin (HP:0001030)1.92452679
89Postural instability (HP:0002172)1.92260179
90Hypoventilation (HP:0002791)1.92080250
91Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.92046303
92Exercise-induced myalgia (HP:0003738)1.91895259
93Drooling (HP:0002307)1.91869023
94Excessive salivation (HP:0003781)1.91869023
95Concave nail (HP:0001598)1.90527341
96Muscle fiber inclusion bodies (HP:0100299)1.90341769
97Dysmetria (HP:0001310)1.90037592
98Hypercortisolism (HP:0001578)1.87905274
99Ankyloglossia (HP:0010296)1.87559484
100Stridor (HP:0010307)1.86358925
101Long palpebral fissure (HP:0000637)1.86062759
102Arnold-Chiari malformation (HP:0002308)1.85175188
103Shawl scrotum (HP:0000049)1.84969426
104Aplasia involving bones of the extremities (HP:0009825)1.84780511
105Aplasia involving bones of the upper limbs (HP:0009823)1.84780511
106Aplasia of the phalanges of the hand (HP:0009802)1.84780511
107Segmental peripheral demyelination/remyelination (HP:0003481)1.84752776
108Elfin facies (HP:0004428)1.84734679
109Lower limb muscle weakness (HP:0007340)1.83785764
110Ulnar deviation of the wrist (HP:0003049)1.83562820
111Hypotrichosis (HP:0001006)1.83002474
112Abnormal eating behavior (HP:0100738)1.82937248
113Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)1.82176051
114Spastic gait (HP:0002064)1.81395779
115Difficulty climbing stairs (HP:0003551)1.81229304
116Truncal ataxia (HP:0002078)1.79631918
117Abnormality of skeletal muscle fiber size (HP:0012084)1.79291250
118Diminished motivation (HP:0000745)1.78746279
119Neonatal short-limb short stature (HP:0008921)1.78283495
120Spinal canal stenosis (HP:0003416)1.78181532
121Atelectasis (HP:0100750)1.77404324
122Buphthalmos (HP:0000557)1.77233844
123Overriding aorta (HP:0002623)1.77045432
124Milia (HP:0001056)1.76059594
125Increased connective tissue (HP:0009025)1.75163245
126Hyperextensible skin (HP:0000974)1.75159891
127Ulnar claw (HP:0001178)1.73774973
128Slender build (HP:0001533)1.73232340
129Torticollis (HP:0000473)1.71051921
130Aqueductal stenosis (HP:0002410)1.70941540
131Waddling gait (HP:0002515)1.70603125
132Onion bulb formation (HP:0003383)1.69834238
133Limb dystonia (HP:0002451)1.69612380
134Abnormality of the phalanges of the hallux (HP:0010057)1.69312134
135Turricephaly (HP:0000262)1.69251127
136Stereotypic behavior (HP:0000733)1.69042179
137Atrophic scars (HP:0001075)1.68818352
138Congenital malformation of the right heart (HP:0011723)1.68290863
139Double outlet right ventricle (HP:0001719)1.68290863
140Hamartoma of the eye (HP:0010568)1.68061254
141Gaze-evoked nystagmus (HP:0000640)1.67180026
142Centrally nucleated skeletal muscle fibers (HP:0003687)1.66300001
143Renovascular hypertension (HP:0100817)1.66161163
144Partial duplication of the phalanx of hand (HP:0009999)1.65346323
145Impaired smooth pursuit (HP:0007772)1.65219889
146Bowel incontinence (HP:0002607)1.63107004
147Flat cornea (HP:0007720)1.62717727
148Overgrowth (HP:0001548)1.62615015
149Deep palmar crease (HP:0006191)1.61475773
150Fetal akinesia sequence (HP:0001989)1.61076673
151Deviation of the hallux (HP:0010051)1.60555241
152Transposition of the great arteries (HP:0001669)1.59895879
153Abnormal connection of the cardiac segments (HP:0011545)1.59895879
154Abnormal ventriculo-arterial connection (HP:0011563)1.59895879
155Exotropia (HP:0000577)1.58527836
156Genu recurvatum (HP:0002816)1.58380617
157Intention tremor (HP:0002080)1.56511864
158Abnormality of the musculature of the hand (HP:0001421)1.56506749

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K93.69867548
2MARK13.45864471
3NTRK32.70850837
4TYRO32.56749481
5EPHA42.50408869
6LATS22.40784076
7PAK62.33706644
8SIK12.29357096
9TRIB32.25905210
10MINK12.23429982
11MAP3K42.11763282
12KSR22.00074878
13SIK21.93307295
14NTRK21.90741040
15PRKD31.90334278
16NTRK11.88440040
17ICK1.86238033
18DAPK21.77055154
19RIPK11.74043652
20PHKG21.65751717
21PHKG11.65751717
22TAOK11.62260278
23ARAF1.56180040
24DMPK1.46905214
25TAOK21.42965091
26MAP2K41.40753257
27PNCK1.39566717
28EPHB21.33329677
29MAP2K31.33118522
30UHMK11.31260902
31STK381.30688169
32CAMKK11.28616138
33RIPK41.28073085
34CDK51.25465418
35GRK51.25198236
36PKN21.24626416
37ERN11.24372614
38DDR21.21234885
39FGR1.19872244
40SMG11.14895749
41KSR11.14115481
42MAP3K101.13887346
43PDGFRA1.11231680
44ALK1.11094356
45SGK4941.10963083
46SGK2231.10963083
47CAMK1D1.09342246
48BMX1.08610799
49PTK2B1.07726686
50RET1.07012763
51MARK21.06953952
52CAMK1G1.06266404
53FER1.05528608
54MAP3K111.05095534
55PRKD21.04521882
56PAK31.03788115
57SGK31.01009277
58TIE10.99316545
59FES0.98151569
60BRAF0.94725750
61MAP3K60.93015192
62MAP2K70.92065643
63EEF2K0.90973203
64CDK140.90735884
65PDPK10.89544465
66RPS6KL10.89400425
67RPS6KC10.89400425
68MAP3K20.89078928
69DAPK10.88700983
70CDK150.85965481
71MAPK130.84116147
72MAP3K70.83530109
73DYRK1B0.81602615
74CDK180.80781051
75RPS6KA60.79489438
76CDK11A0.77855434
77CASK0.77609818
78PRKCH0.76494021
79* STK110.75510119
80CDC42BPA0.74563669
81SGK20.73365481
82PTK20.72220605
83IRAK30.72006802
84MAP3K10.71808810
85FGFR40.71307640
86RPS6KA20.70950254
87MOS0.69010541
88DYRK20.68623332
89PLK20.67006246
90CAMK2A0.66605966
91PRPF4B0.66501882
92PRKCG0.66367688
93LMTK20.65065725
94MAPK70.64748643
95OBSCN0.62595026
96HIPK20.61904718
97PDK10.60897920
98CAMK10.58465818
99PRKD10.57442757
100PKN10.56890162
101PTK60.55225623
102MAP2K20.54938234
103PRKG20.54351821
104CDK120.53975993
105PRKAA10.52800112
106DYRK1A0.51225750
107PRKCZ0.49939129
108MAPK120.49764877
109MAP3K120.49189466
110FYN0.48593686
111TTN0.48121712
112MAP2K10.47655216
113MAPK80.47271562
114RPS6KA10.46708514
115MAPK40.46699817
116EPHB10.46679501
117ROCK20.46388306
118PDGFRB0.45946458
119WNK10.45826621
120CAMK40.45352906
121SGK10.45248293
122LIMK10.45173672
123MAPK150.45102545
124MTOR0.45027260
125FGFR20.44756624
126MAPK100.44184561
127ROCK10.43608986
128CSNK1G20.42854893
129DAPK30.42551624
130TNK20.42237212
131MAP3K130.41514327
132PAK20.41107633
133RPS6KA30.40798579
134RAF10.36714794
135CDK190.36342976

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.35521821
2Synaptic vesicle cycle_Homo sapiens_hsa047212.27306319
3Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.26641951
4Long-term potentiation_Homo sapiens_hsa047202.06886455
5Circadian entrainment_Homo sapiens_hsa047131.95307574
6Glutamatergic synapse_Homo sapiens_hsa047241.91999316
7GABAergic synapse_Homo sapiens_hsa047271.91887972
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.83495884
9Olfactory transduction_Homo sapiens_hsa047401.81112855
10Salivary secretion_Homo sapiens_hsa049701.75554129
11Dopaminergic synapse_Homo sapiens_hsa047281.74992917
12Morphine addiction_Homo sapiens_hsa050321.69159604
13Amphetamine addiction_Homo sapiens_hsa050311.68268414
14Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.67931212
15Axon guidance_Homo sapiens_hsa043601.65015401
16Gastric acid secretion_Homo sapiens_hsa049711.64962700
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.60640077
18Cholinergic synapse_Homo sapiens_hsa047251.58575057
19Renin secretion_Homo sapiens_hsa049241.56942406
20Oxytocin signaling pathway_Homo sapiens_hsa049211.54543194
21GnRH signaling pathway_Homo sapiens_hsa049121.53982667
22Long-term depression_Homo sapiens_hsa047301.49910274
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.48883301
24Glioma_Homo sapiens_hsa052141.47675837
25Gap junction_Homo sapiens_hsa045401.46403155
26Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.45828458
27Dorso-ventral axis formation_Homo sapiens_hsa043201.45537226
28Insulin secretion_Homo sapiens_hsa049111.39817078
29Estrogen signaling pathway_Homo sapiens_hsa049151.38771255
30Prion diseases_Homo sapiens_hsa050201.35724017
31VEGF signaling pathway_Homo sapiens_hsa043701.33442066
32ErbB signaling pathway_Homo sapiens_hsa040121.29773061
33Melanogenesis_Homo sapiens_hsa049161.27006041
34Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26635968
35Cocaine addiction_Homo sapiens_hsa050301.26597547
36Serotonergic synapse_Homo sapiens_hsa047261.24083981
37Calcium signaling pathway_Homo sapiens_hsa040201.20520007
38Dilated cardiomyopathy_Homo sapiens_hsa054141.19603313
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.16453544
40cAMP signaling pathway_Homo sapiens_hsa040241.13242785
41Type II diabetes mellitus_Homo sapiens_hsa049301.11043185
42Phospholipase D signaling pathway_Homo sapiens_hsa040721.10105267
43Taste transduction_Homo sapiens_hsa047421.07199473
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.06791968
45Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.06022367
46Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.04535154
47Cardiac muscle contraction_Homo sapiens_hsa042601.03963283
48Renal cell carcinoma_Homo sapiens_hsa052111.03505262
49AMPK signaling pathway_Homo sapiens_hsa041521.01933276
50mTOR signaling pathway_Homo sapiens_hsa041501.01411582
51Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.00921015
52Neurotrophin signaling pathway_Homo sapiens_hsa047220.99827510
53Phosphatidylinositol signaling system_Homo sapiens_hsa040700.99217176
54Endometrial cancer_Homo sapiens_hsa052130.95883512
55Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.95560322
56Hedgehog signaling pathway_Homo sapiens_hsa043400.94678232
57Choline metabolism in cancer_Homo sapiens_hsa052310.94480742
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.91887965
59Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.90692118
60Thyroid hormone signaling pathway_Homo sapiens_hsa049190.90469324
61Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.87896442
62MAPK signaling pathway_Homo sapiens_hsa040100.87257628
63Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.86863932
64Rap1 signaling pathway_Homo sapiens_hsa040150.85814801
65Endocytosis_Homo sapiens_hsa041440.85061171
66Sulfur relay system_Homo sapiens_hsa041220.84174059
67Hippo signaling pathway_Homo sapiens_hsa043900.83033817
68Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.81972102
69Wnt signaling pathway_Homo sapiens_hsa043100.80503879
70Sphingolipid signaling pathway_Homo sapiens_hsa040710.77838613
71Tight junction_Homo sapiens_hsa045300.76889399
72Acute myeloid leukemia_Homo sapiens_hsa052210.76866334
73Ras signaling pathway_Homo sapiens_hsa040140.76397632
74Non-small cell lung cancer_Homo sapiens_hsa052230.76116006
75Circadian rhythm_Homo sapiens_hsa047100.75987932
76Oocyte meiosis_Homo sapiens_hsa041140.75748853
77Focal adhesion_Homo sapiens_hsa045100.75732626
78Basal cell carcinoma_Homo sapiens_hsa052170.75675053
79Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.75358612
80Insulin resistance_Homo sapiens_hsa049310.74421034
81Proteoglycans in cancer_Homo sapiens_hsa052050.74091269
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73188320
83Inositol phosphate metabolism_Homo sapiens_hsa005620.72855170
84Regulation of actin cytoskeleton_Homo sapiens_hsa048100.72584060
85Amoebiasis_Homo sapiens_hsa051460.72417845
86Insulin signaling pathway_Homo sapiens_hsa049100.71209717
87Colorectal cancer_Homo sapiens_hsa052100.71112649
88Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.69929622
89Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69802735
90Pancreatic secretion_Homo sapiens_hsa049720.69175895
91Adipocytokine signaling pathway_Homo sapiens_hsa049200.68171812
92AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.67689942
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67554871
94Bile secretion_Homo sapiens_hsa049760.67309290
95Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.66363472
96Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.65564402
97Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64158624
98Central carbon metabolism in cancer_Homo sapiens_hsa052300.61937424
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.59636777
100MicroRNAs in cancer_Homo sapiens_hsa052060.59497076
101B cell receptor signaling pathway_Homo sapiens_hsa046620.58732678
102FoxO signaling pathway_Homo sapiens_hsa040680.58729720
103Chronic myeloid leukemia_Homo sapiens_hsa052200.57980530
104Adherens junction_Homo sapiens_hsa045200.57425271
105Bladder cancer_Homo sapiens_hsa052190.56759936
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55304962
107Collecting duct acid secretion_Homo sapiens_hsa049660.54553802
108Notch signaling pathway_Homo sapiens_hsa043300.52446770
109Glucagon signaling pathway_Homo sapiens_hsa049220.52207920
110Chemokine signaling pathway_Homo sapiens_hsa040620.51723217
111Platelet activation_Homo sapiens_hsa046110.51424833
112ECM-receptor interaction_Homo sapiens_hsa045120.50094069
113Thyroid hormone synthesis_Homo sapiens_hsa049180.50004791
114Prolactin signaling pathway_Homo sapiens_hsa049170.49487762
115Fatty acid biosynthesis_Homo sapiens_hsa000610.49182491
116Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.48744782

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »