MARS

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1folic acid-containing compound biosynthetic process (GO:0009396)5.91309734
2DNA unwinding involved in DNA replication (GO:0006268)5.18982649
3formation of translation preinitiation complex (GO:0001731)4.86017439
4regulation of translational fidelity (GO:0006450)4.80657602
5nucleobase biosynthetic process (GO:0046112)4.62507317
6IMP biosynthetic process (GO:0006188)4.46826047
7establishment of integrated proviral latency (GO:0075713)4.38780293
8DNA strand elongation involved in DNA replication (GO:0006271)4.37291895
9nuclear pore organization (GO:0006999)4.36340076
10DNA replication initiation (GO:0006270)4.28890219
11mitotic nuclear envelope disassembly (GO:0007077)4.23109947
12protein localization to kinetochore (GO:0034501)4.22675023
13DNA replication-dependent nucleosome assembly (GO:0006335)4.15412007
14DNA replication-dependent nucleosome organization (GO:0034723)4.15412007
15DNA strand elongation (GO:0022616)4.09481232
16folic acid metabolic process (GO:0046655)4.02403309
17nuclear envelope disassembly (GO:0051081)3.97271307
18membrane disassembly (GO:0030397)3.97271307
19purine nucleobase biosynthetic process (GO:0009113)3.96950563
20tetrahydrofolate metabolic process (GO:0046653)3.95239402
21IMP metabolic process (GO:0046040)3.94301078
22nuclear pore complex assembly (GO:0051292)3.93673704
23maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.91688245
24establishment of viral latency (GO:0019043)3.91025921
25ribosome assembly (GO:0042255)3.88617874
26maturation of SSU-rRNA (GO:0030490)3.78495121
27regulation of translational termination (GO:0006449)3.77884572
28regulation of gene silencing by RNA (GO:0060966)3.73860906
29regulation of posttranscriptional gene silencing (GO:0060147)3.73860906
30regulation of gene silencing by miRNA (GO:0060964)3.73860906
31L-serine metabolic process (GO:0006563)3.67474182
32protein retention in ER lumen (GO:0006621)3.64786867
33pteridine-containing compound biosynthetic process (GO:0042559)3.61419616
34telomere maintenance via semi-conservative replication (GO:0032201)3.61139275
35ribosome biogenesis (GO:0042254)3.59227992
36DNA duplex unwinding (GO:0032508)3.58885102
37DNA geometric change (GO:0032392)3.56487574
38glycine metabolic process (GO:0006544)3.48552260
39* tRNA aminoacylation for protein translation (GO:0006418)3.47650096
40heterochromatin organization (GO:0070828)3.47552727
41mitotic metaphase plate congression (GO:0007080)3.46753571
42folic acid-containing compound metabolic process (GO:0006760)3.46659201
43peptidyl-arginine omega-N-methylation (GO:0035247)3.43447355
44DNA topological change (GO:0006265)3.37185311
45protein localization to chromosome, centromeric region (GO:0071459)3.36452953
46DNA replication checkpoint (GO:0000076)3.35758445
47* tRNA aminoacylation (GO:0043039)3.33805835
48* amino acid activation (GO:0043038)3.33805835
49pre-miRNA processing (GO:0031054)3.32966746
50serine family amino acid biosynthetic process (GO:0009070)3.28052147
51retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)3.27117888
52mitochondrial DNA metabolic process (GO:0032042)3.23430965
53chaperone-mediated protein complex assembly (GO:0051131)3.22544494
54nuclear envelope organization (GO:0006998)3.18053627
55protein export from nucleus (GO:0006611)3.17481158
56ribonucleoprotein complex biogenesis (GO:0022613)3.17143733
57translational initiation (GO:0006413)3.12988708
58ribosomal large subunit biogenesis (GO:0042273)3.12474246
59mitotic chromosome condensation (GO:0007076)3.11167099
60negative regulation of mRNA processing (GO:0050686)3.09848662
61regulation of translational elongation (GO:0006448)3.09737299
62mitotic sister chromatid segregation (GO:0000070)3.08832783
63histone arginine methylation (GO:0034969)3.08483943
64telomere maintenance via recombination (GO:0000722)3.07823267
65somatic hypermutation of immunoglobulin genes (GO:0016446)3.07093897
66somatic diversification of immune receptors via somatic mutation (GO:0002566)3.07093897
67negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.03914891
68regulation of spindle organization (GO:0090224)3.03561176
69non-recombinational repair (GO:0000726)3.02983994
70double-strand break repair via nonhomologous end joining (GO:0006303)3.02983994
71regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.02874614
72negative regulation of histone methylation (GO:0031061)3.01378654
73pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)3.00214331
74spliceosomal tri-snRNP complex assembly (GO:0000244)2.99363824
75mitotic recombination (GO:0006312)2.99087644
76regulation of histone H3-K9 methylation (GO:0051570)2.99050941
77telomere maintenance via telomere lengthening (GO:0010833)2.98236297
78translational elongation (GO:0006414)2.97576169
79one-carbon metabolic process (GO:0006730)2.97336986
80sister chromatid segregation (GO:0000819)2.95145962
81glutamine metabolic process (GO:0006541)2.95129552
82translational termination (GO:0006415)2.93798927
83pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.92511494
84UMP biosynthetic process (GO:0006222)2.92511494
85pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.92511494
86UMP metabolic process (GO:0046049)2.92511494
87viral transcription (GO:0019083)2.92162852
88metaphase plate congression (GO:0051310)2.90981742
89mitotic nuclear envelope reassembly (GO:0007084)2.90186958
90nuclear envelope reassembly (GO:0031468)2.90186958
91spliceosomal snRNP assembly (GO:0000387)2.88102767
92mitotic G1 DNA damage checkpoint (GO:0031571)2.87970590
93positive regulation of chromosome segregation (GO:0051984)2.87815681
94nucleosome disassembly (GO:0006337)2.87655948
95protein-DNA complex disassembly (GO:0032986)2.87655948
96negative regulation of mRNA metabolic process (GO:1903312)2.87587675
97pore complex assembly (GO:0046931)2.84583742
98proline biosynthetic process (GO:0006561)2.84009417
99nucleobase-containing small molecule interconversion (GO:0015949)2.83564617
100protein maturation by protein folding (GO:0022417)2.82929865
101pteridine-containing compound metabolic process (GO:0042558)2.82085717
102rRNA processing (GO:0006364)2.82044000
103cellular protein complex localization (GO:0034629)2.81183966
104regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.80575836
105mitotic sister chromatid cohesion (GO:0007064)2.80383198
106peptidyl-arginine N-methylation (GO:0035246)2.79613298
107peptidyl-arginine methylation (GO:0018216)2.79613298
108nucleotide-excision repair, DNA gap filling (GO:0006297)2.79036653
109ribosomal small subunit assembly (GO:0000028)2.77633400
110Golgi transport vesicle coating (GO:0048200)2.77068708
111COPI coating of Golgi vesicle (GO:0048205)2.77068708
112regulation of helicase activity (GO:0051095)2.75965456
113regulation of centrosome cycle (GO:0046605)2.75395641
114nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.73925575
115regulation of mitotic spindle organization (GO:0060236)2.72612678
116DNA conformation change (GO:0071103)2.72045730
117rRNA metabolic process (GO:0016072)2.71862585
118negative regulation of translational initiation (GO:0045947)2.71606282
119pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.70703213
120chromatin assembly (GO:0031497)2.70066173
121proline metabolic process (GO:0006560)2.69687605
122protein complex localization (GO:0031503)2.68067827
123positive regulation of nuclease activity (GO:0032075)2.66803034
124negative regulation of RNA splicing (GO:0033119)2.66735879
125activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.66228641
126mRNA transport (GO:0051028)2.63720100
127vesicle coating (GO:0006901)2.63646379
128tRNA methylation (GO:0030488)2.63400184
129intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)2.62111687
130regulation of RNA export from nucleus (GO:0046831)2.60649798
131COPII vesicle coating (GO:0048208)2.60031162
132pentose-phosphate shunt (GO:0006098)2.60008016
133NADPH regeneration (GO:0006740)2.59185984
134regulation of mitochondrial translation (GO:0070129)2.58128792
135chromosome segregation (GO:0007059)2.57631517
136regulation of mammary gland epithelial cell proliferation (GO:0033599)2.56910485
137de novo protein folding (GO:0006458)2.56560253

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.42201520
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.15745857
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.87006609
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.65152959
5MYC_19079543_ChIP-ChIP_MESCs_Mouse3.04262474
6E2F4_17652178_ChIP-ChIP_JURKAT_Human2.89954966
7* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.68775458
8* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.62722326
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.53097240
10* ETS1_20019798_ChIP-Seq_JURKAT_Human2.36000977
11NELFA_20434984_ChIP-Seq_ESCs_Mouse2.27971533
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.23643495
13XRN2_22483619_ChIP-Seq_HELA_Human2.23464415
14* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.21510507
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.16307418
16MYC_22102868_ChIP-Seq_BL_Human2.14998481
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.12967892
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.12766869
19GABP_17652178_ChIP-ChIP_JURKAT_Human1.98706568
20HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.97351928
21* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.92043455
22AR_21909140_ChIP-Seq_LNCAP_Human1.91434568
23* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.88618319
24* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85939420
25NANOG_18555785_ChIP-Seq_MESCs_Mouse1.84119095
26POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.80599016
27NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.78585801
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.75604597
29SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.74832123
30E2F1_21310950_ChIP-Seq_MCF-7_Human1.73536811
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.71896622
32DCP1A_22483619_ChIP-Seq_HELA_Human1.71015903
33VDR_23849224_ChIP-Seq_CD4+_Human1.70877037
34GABP_19822575_ChIP-Seq_HepG2_Human1.69484121
35STAT3_1855785_ChIP-Seq_MESCs_Mouse1.69259847
36ZFX_18555785_ChIP-Seq_MESCs_Mouse1.68905347
37CIITA_25753668_ChIP-Seq_RAJI_Human1.68880231
38* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.67122691
39* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.66771549
40* FOXP3_21729870_ChIP-Seq_TREG_Human1.60583723
41* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.58546396
42TTF2_22483619_ChIP-Seq_HELA_Human1.54039304
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50683130
44* KDM5A_27292631_Chip-Seq_BREAST_Human1.48754673
45* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.46572185
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.40534374
47* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.40127755
48TFEB_21752829_ChIP-Seq_HELA_Human1.38624663
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34100341
50DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.33438008
51PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.32238838
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.31655938
53NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.31467372
54TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29537007
55ESR1_15608294_ChIP-ChIP_MCF-7_Human1.29408496
56* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.28652821
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.27653108
58KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.27482377
59KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.27482377
60KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.27482377
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.26754712
62SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.21719296
63YY1_21170310_ChIP-Seq_MESCs_Mouse1.21586484
64ZNF263_19887448_ChIP-Seq_K562_Human1.21114382
65ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.20689315
66VDR_21846776_ChIP-Seq_THP-1_Human1.19471440
67FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.18673689
68SOX2_18555785_ChIP-Seq_MESCs_Mouse1.17933917
69POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.17914649
70SRF_21415370_ChIP-Seq_HL-1_Mouse1.17316572
71TCF3_18692474_ChIP-Seq_MEFs_Mouse1.16997438
72SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.15586700
73ELF1_17652178_ChIP-ChIP_JURKAT_Human1.14900994
74ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.12858838
75TP63_17297297_ChIP-ChIP_HaCaT_Human1.12494574
76NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.09295586
77TBX5_21415370_ChIP-Seq_HL-1_Mouse1.08386961
78KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.07921273
79CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.07788708
80DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.06868150
81E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06391652
82ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.05502276
83NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.05185774
84* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04589989
85SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.04208555
86* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.04053821
87* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.03060946
88HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.02259464
89* ATF3_27146783_Chip-Seq_COLON_Human1.02242980
90OCT4_18692474_ChIP-Seq_MEFs_Mouse1.01374301
91NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.00983611
92CLOCK_20551151_ChIP-Seq_293T_Human1.00774517
93PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.00398994
94ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.00312967
95NANOG_21062744_ChIP-ChIP_HESCs_Human1.00223043
96* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99740547
97* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98917466
98* ELK1_19687146_ChIP-ChIP_HELA_Human0.96890132
99ELK3_25401928_ChIP-Seq_HUVEC_Human0.94500509
100SOX2_18692474_ChIP-Seq_MEFs_Mouse0.94183575
101TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94127427
102PADI4_21655091_ChIP-ChIP_MCF-7_Human0.93572193
103E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.93451146
104ZFP281_18757296_ChIP-ChIP_E14_Mouse0.93057576
105ERG_20887958_ChIP-Seq_HPC-7_Mouse0.92514146
106CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.91726374
107* CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.91650003
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91413291
109* FOXP1_21924763_ChIP-Seq_HESCs_Human0.90859016
110* HOXB4_20404135_ChIP-ChIP_EML_Mouse0.90073928
111FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.89280681
112RACK7_27058665_Chip-Seq_MCF-7_Human0.88207377
113TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.88021152
114NCOR1_26117541_ChIP-Seq_K562_Human0.87697606
115PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.87575585
116HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.85540947
117CHD1_26751641_Chip-Seq_LNCaP_Human0.85471230

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.69991507
2MP0004957_abnormal_blastocyst_morpholog4.09979042
3MP0003111_abnormal_nucleus_morphology3.84352441
4MP0010094_abnormal_chromosome_stability3.61262758
5MP0003806_abnormal_nucleotide_metabolis3.37098231
6MP0003077_abnormal_cell_cycle3.36490857
7MP0010352_gastrointestinal_tract_polyps3.23151215
8MP0001730_embryonic_growth_arrest2.77483974
9MP0008057_abnormal_DNA_replication2.75126757
10MP0003705_abnormal_hypodermis_morpholog2.67416848
11MP0008058_abnormal_DNA_repair2.32676397
12MP0000350_abnormal_cell_proliferation2.23987076
13MP0008932_abnormal_embryonic_tissue2.21106513
14MP0010307_abnormal_tumor_latency2.12959325
15MP0003123_paternal_imprinting2.08471369
16MP0008007_abnormal_cellular_replicative2.06423515
17MP0005380_embryogenesis_phenotype1.98657677
18MP0001672_abnormal_embryogenesis/_devel1.98657677
19MP0001697_abnormal_embryo_size1.91817697
20MP0005076_abnormal_cell_differentiation1.90980464
21MP0008260_abnormal_autophagy1.89089877
22MP0005451_abnormal_body_composition1.84319081
23MP0002080_prenatal_lethality1.82634265
24MP0003984_embryonic_growth_retardation1.81728867
25MP0004197_abnormal_fetal_growth/weight/1.78859647
26MP0002088_abnormal_embryonic_growth/wei1.78698078
27MP0002084_abnormal_developmental_patter1.77688738
28MP0010030_abnormal_orbit_morphology1.73094261
29MP0002085_abnormal_embryonic_tissue1.72251290
30MP0004133_heterotaxia1.63930358
31MP0002086_abnormal_extraembryonic_tissu1.63024192
32MP0000537_abnormal_urethra_morphology1.56358545
33MP0003283_abnormal_digestive_organ1.51101176
34MP0003890_abnormal_embryonic-extraembry1.49127302
35MP0009840_abnormal_foam_cell1.48303953
36MP0002396_abnormal_hematopoietic_system1.42332812
37MP0003119_abnormal_digestive_system1.41144760
38MP0003941_abnormal_skin_development1.40328375
39MP0004233_abnormal_muscle_weight1.40054642
40MP0000490_abnormal_crypts_of1.37347123
41MP0004858_abnormal_nervous_system1.36972769
42MP0002254_reproductive_system_inflammat1.36086710
43MP0001529_abnormal_vocalization1.34109599
44MP0005023_abnormal_wound_healing1.33991543
45MP0001293_anophthalmia1.30251529
46MP0003786_premature_aging1.29199302
47MP0005394_taste/olfaction_phenotype1.29151794
48MP0005499_abnormal_olfactory_system1.29151794
49MP0000313_abnormal_cell_death1.28998393
50MP0005083_abnormal_biliary_tract1.27864000
51MP0002019_abnormal_tumor_incidence1.26650890
52MP0009672_abnormal_birth_weight1.25394288
53MP0002653_abnormal_ependyma_morphology1.24298433
54MP0003567_abnormal_fetal_cardiomyocyte1.24219817
55MP0003566_abnormal_cell_adhesion1.23261124
56MP0010234_abnormal_vibrissa_follicle1.19709020
57MP0000358_abnormal_cell_content/1.18368849
58MP0009053_abnormal_anal_canal1.18004731
59MP0002269_muscular_atrophy1.14726264
60MP0002796_impaired_skin_barrier1.11045484
61MP0001299_abnormal_eye_distance/1.03597917
62MP0004185_abnormal_adipocyte_glucose1.03596660
63MP0008877_abnormal_DNA_methylation1.02371604
64MP0005623_abnormal_meninges_morphology1.01646880
65MP0005220_abnormal_exocrine_pancreas1.01578680
66MP0000678_abnormal_parathyroid_gland1.01147851
67MP0005365_abnormal_bile_salt1.00915875
68MP0003385_abnormal_body_wall1.00178496
69MP0002111_abnormal_tail_morphology0.98254504
70MP0003718_maternal_effect0.97416577
71MP0003861_abnormal_nervous_system0.95413109
72MP0008789_abnormal_olfactory_epithelium0.95371475
73MP0004264_abnormal_extraembryonic_tissu0.94211132
74MP0001849_ear_inflammation0.92578396
75MP0001348_abnormal_lacrimal_gland0.92374829
76MP0003937_abnormal_limbs/digits/tail_de0.90472305
77MP0005384_cellular_phenotype0.90335514
78MP0000750_abnormal_muscle_regeneration0.89526156
79MP0005621_abnormal_cell_physiology0.88980484
80MP0001915_intracranial_hemorrhage0.88828478
81MP0003942_abnormal_urinary_system0.88476754
82MP0009703_decreased_birth_body0.87332641
83MP0000598_abnormal_liver_morphology0.87149859
84MP0002139_abnormal_hepatobiliary_system0.85637117
85MP0004782_abnormal_surfactant_physiolog0.85341860
86MP0000566_synostosis0.85183496
87MP0002092_abnormal_eye_morphology0.85130581
88MP0001661_extended_life_span0.84320018
89MP0006054_spinal_hemorrhage0.83900328
90MP0000579_abnormal_nail_morphology0.83774337
91MP0004808_abnormal_hematopoietic_stem0.83245872
92MP0000428_abnormal_craniofacial_morphol0.83232834
93MP0001727_abnormal_embryo_implantation0.82947651
94MP0002877_abnormal_melanocyte_morpholog0.82764345
95MP0005257_abnormal_intraocular_pressure0.82641968
96MP0004272_abnormal_basement_membrane0.82548955
97MP0000733_abnormal_muscle_development0.82322677
98MP0003315_abnormal_perineum_morphology0.81582306
99MP0002697_abnormal_eye_size0.81132872
100MP0003221_abnormal_cardiomyocyte_apopto0.81128163
101MP0005666_abnormal_adipose_tissue0.80560994
102MP0008438_abnormal_cutaneous_collagen0.80327289
103MP0000477_abnormal_intestine_morphology0.77896110
104MP0001145_abnormal_male_reproductive0.77240494
105MP0003656_abnormal_erythrocyte_physiolo0.77211176
106MP0005266_abnormal_metabolism0.77065783
107MP0000747_muscle_weakness0.76305418
108MP0000371_diluted_coat_color0.75568906
109MP0001666_abnormal_nutrient_absorption0.75262030
110MP0005085_abnormal_gallbladder_physiolo0.75029324
111MP0001346_abnormal_lacrimal_gland0.74389691
112MP0008770_decreased_survivor_rate0.74022313
113MP0001286_abnormal_eye_development0.73765888
114MP0003755_abnormal_palate_morphology0.72687859
115MP0000703_abnormal_thymus_morphology0.71942469
116MP0009333_abnormal_splenocyte_physiolog0.71153743
117MP0003186_abnormal_redox_activity0.71073982
118MP0000858_altered_metastatic_potential0.70431880
119MP0002210_abnormal_sex_determination0.70430208
120MP0002060_abnormal_skin_morphology0.70107491
121MP0000377_abnormal_hair_follicle0.68808960
122MP0001881_abnormal_mammary_gland0.67060526
123MP0000609_abnormal_liver_physiology0.66566521
124MP0000003_abnormal_adipose_tissue0.65816819
125MP0002089_abnormal_postnatal_growth/wei0.65753976
126MP0006035_abnormal_mitochondrial_morpho0.65039804
127MP0005360_urolithiasis0.62059588
128MP0003115_abnormal_respiratory_system0.62055013
129MP0003121_genomic_imprinting0.60898302
130MP0002722_abnormal_immune_system0.60627308
131MP0002970_abnormal_white_adipose0.59438712
132MP0005501_abnormal_skin_physiology0.58822849
133MP0001243_abnormal_dermal_layer0.58061764
134MP0002925_abnormal_cardiovascular_devel0.57485710
135MP0000266_abnormal_heart_morphology0.56847237

Predicted human phenotypes

RankGene SetZ-score
1Upper limb muscle weakness (HP:0003484)4.96256831
2Ependymoma (HP:0002888)4.80237413
3Cholecystitis (HP:0001082)4.01337257
4Abnormal gallbladder physiology (HP:0012438)4.01337257
5Microvesicular hepatic steatosis (HP:0001414)3.82761877
6Selective tooth agenesis (HP:0001592)3.44057477
7Birth length less than 3rd percentile (HP:0003561)3.42421265
8Abnormality of the astrocytes (HP:0100707)3.30763007
9Astrocytoma (HP:0009592)3.30763007
10Colon cancer (HP:0003003)3.24760289
11Breast hypoplasia (HP:0003187)3.21645913
12Chromosomal breakage induced by crosslinking agents (HP:0003221)3.17407990
13Chromsome breakage (HP:0040012)3.05065238
14Insomnia (HP:0100785)3.01954869
15Degeneration of anterior horn cells (HP:0002398)3.01910937
16Abnormality of the anterior horn cell (HP:0006802)3.01910937
17Trismus (HP:0000211)2.96109381
18Medulloblastoma (HP:0002885)2.94748877
19Oral leukoplakia (HP:0002745)2.94704550
20Spastic diplegia (HP:0001264)2.82838580
21Adenoma sebaceum (HP:0009720)2.74568513
22Angiofibromas (HP:0010615)2.74568513
23Multiple enchondromatosis (HP:0005701)2.70375984
24Glioma (HP:0009733)2.64908679
25Long palpebral fissure (HP:0000637)2.64809020
26Abnormality of pyrimidine metabolism (HP:0004353)2.64308638
27Basal cell carcinoma (HP:0002671)2.61592377
28Reticulocytopenia (HP:0001896)2.59918824
29Rhabdomyosarcoma (HP:0002859)2.55982976
30Long foot (HP:0001833)2.53706911
31Carpal bone hypoplasia (HP:0001498)2.47686308
32Proximal placement of thumb (HP:0009623)2.44852460
33Agnosia (HP:0010524)2.44391370
34Hand muscle atrophy (HP:0009130)2.43722905
35Deviation of the thumb (HP:0009603)2.41405463
36Missing ribs (HP:0000921)2.39867598
37Abnormality of the calcaneus (HP:0008364)2.39571093
38Cerebral hypomyelination (HP:0006808)2.37239976
39Neoplasm of the pancreas (HP:0002894)2.36857117
40Abnormality of cells of the erythroid lineage (HP:0012130)2.35961585
41Reticulocytosis (HP:0001923)2.33278878
42Atrophy/Degeneration involving motor neurons (HP:0007373)2.31684705
43Neoplasm of striated muscle (HP:0009728)2.31013961
44Biliary tract neoplasm (HP:0100574)2.27551123
45Progressive muscle weakness (HP:0003323)2.24533484
46Back pain (HP:0003418)2.23434582
47Abnormality of monocarboxylic acid metabolism (HP:0010996)2.21803075
48Cholelithiasis (HP:0001081)2.20344848
49Overriding aorta (HP:0002623)2.19955041
50Abnormality of the lower motor neuron (HP:0002366)2.15516518
51Patellar aplasia (HP:0006443)2.15492258
52Absent thumb (HP:0009777)2.15467934
53Postnatal microcephaly (HP:0005484)2.14357736
54Abnormal number of erythroid precursors (HP:0012131)2.12957643
55Pterygium (HP:0001059)2.12260562
56Shoulder girdle muscle weakness (HP:0003547)2.12012752
57Absent radius (HP:0003974)2.11077842
58Aplasia/hypoplasia of the humerus (HP:0006507)2.10856522
59Neoplasm of the oral cavity (HP:0100649)2.10654963
60Premature skin wrinkling (HP:0100678)2.09645903
61Rough bone trabeculation (HP:0100670)2.09374104
62Upper limb amyotrophy (HP:0009129)2.08167475
63Distal upper limb amyotrophy (HP:0007149)2.08167475
64Premature rupture of membranes (HP:0001788)2.07765401
65Protrusio acetabuli (HP:0003179)2.07565406
66Hammertoe (HP:0001765)2.06845760
67Microretrognathia (HP:0000308)2.06389538
68Hyperacusis (HP:0010780)2.05219913
69Horseshoe kidney (HP:0000085)2.04829327
70Large hands (HP:0001176)2.04492961
71Abnormality of the labia minora (HP:0012880)2.03438534
72Megaloblastic anemia (HP:0001889)2.03283352
73Increased nuchal translucency (HP:0010880)2.02048015
74Abnormality of the umbilical cord (HP:0010881)2.01261879
75Premature ovarian failure (HP:0008209)2.01005447
76Ragged-red muscle fibers (HP:0003200)2.00888769
77Aplasia/Hypoplasia of the patella (HP:0006498)1.99442617
78Calcaneovalgus deformity (HP:0001848)1.98231860
79Impulsivity (HP:0100710)1.97282684
80Rhabdomyolysis (HP:0003201)1.97015566
81Abnormality of abdominal situs (HP:0011620)1.96948943
82Abdominal situs inversus (HP:0003363)1.96948943
83Generalized hypotonia (HP:0001290)1.96693974
84Abnormal gallbladder morphology (HP:0012437)1.96623981
85Aplasia involving forearm bones (HP:0009822)1.94194720
86Absent forearm bone (HP:0003953)1.94194720
87Progressive external ophthalmoplegia (HP:0000590)1.94093733
88Metaphyseal cupping (HP:0003021)1.93803936
89Squamous cell carcinoma (HP:0002860)1.92959887
90Patent foramen ovale (HP:0001655)1.92814842
91Abnormality of reticulocytes (HP:0004312)1.91833305
92Poikiloderma (HP:0001029)1.91107971
93Hypobetalipoproteinemia (HP:0003563)1.90015844
94Truncus arteriosus (HP:0001660)1.89089338
95Short humerus (HP:0005792)1.88981767
96Posterior subcapsular cataract (HP:0007787)1.87618449
97Patellar dislocation (HP:0002999)1.87242935
98Elfin facies (HP:0004428)1.87018201
99Abnormality of the motor neurons (HP:0002450)1.85917144
100Abnormal neuron morphology (HP:0012757)1.85917144
101Preauricular skin tag (HP:0000384)1.85366101
102Neoplasm of the rectum (HP:0100743)1.85350088
103Pseudobulbar signs (HP:0002200)1.85092904
104Orthostatic hypotension (HP:0001278)1.84510579
105Pelvic girdle muscle weakness (HP:0003749)1.84035704
106Macrocytic anemia (HP:0001972)1.83493009
107Cafe-au-lait spot (HP:0000957)1.83142000
108Cortical dysplasia (HP:0002539)1.82860246
109Prominent metopic ridge (HP:0005487)1.82567563
110Increased density of long bones (HP:0006392)1.82346606
111Ovarian neoplasm (HP:0100615)1.82162911
112Entropion (HP:0000621)1.81929446
113Trigonocephaly (HP:0000243)1.80932064
114Ankle contracture (HP:0006466)1.80636403
115High anterior hairline (HP:0009890)1.80075945
116Pointed chin (HP:0000307)1.79775533
117Secondary amenorrhea (HP:0000869)1.79233773
118Increased serum pyruvate (HP:0003542)1.78276142
119Abnormality of glycolysis (HP:0004366)1.78276142
120Atresia of the external auditory canal (HP:0000413)1.77959083
121Overlapping toe (HP:0001845)1.77611145
12211 pairs of ribs (HP:0000878)1.77434202
123High pitched voice (HP:0001620)1.76811443
124Bowel diverticulosis (HP:0005222)1.76717266
125Abnormality of the gallbladder (HP:0005264)1.76660207
126Neoplasm of the colon (HP:0100273)1.76543837
127Deformed tarsal bones (HP:0008119)1.73927770
128Ulnar deviation of the wrist (HP:0003049)1.72762198
129Renal duplication (HP:0000075)1.72529070
130Abnormality of homocysteine metabolism (HP:0010919)1.72104718
131Homocystinuria (HP:0002156)1.72104718
132Abnormality of the musculature of the pelvis (HP:0001469)1.71577365
133Abnormality of the hip-girdle musculature (HP:0001445)1.71577365
134Glossoptosis (HP:0000162)1.70577794
135Slender long bone (HP:0003100)1.70118957
136Hyperthyroidism (HP:0000836)1.69778272
137Personality changes (HP:0000751)1.69589333
138Intestinal polyp (HP:0005266)1.69328948
139Hypoplasia of the pons (HP:0012110)1.69212749
140Rib fusion (HP:0000902)1.68488742
141Abnormal number of incisors (HP:0011064)1.68082994
142Spinal muscular atrophy (HP:0007269)1.67991462
143Achilles tendon contracture (HP:0001771)1.67944778
144Deep palmar crease (HP:0006191)1.67696224
145Prominent nose (HP:0000448)1.67504007
146Abnormality of sulfur amino acid metabolism (HP:0004339)1.67278529
147Vertebral clefting (HP:0008428)1.67137227
148Fibroma (HP:0010614)1.66133194
149Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.64264855
150Abnormal protein N-linked glycosylation (HP:0012347)1.64264855
151Abnormal protein glycosylation (HP:0012346)1.64264855
152Abnormal glycosylation (HP:0012345)1.64264855
153Breech presentation (HP:0001623)1.63735524
154Disproportionate tall stature (HP:0001519)1.63192316
155Abnormality of the pons (HP:0007361)1.62763220
156Abnormality of the preputium (HP:0100587)1.62353538
157Meckel diverticulum (HP:0002245)1.61872556
158Cerebellar hypoplasia (HP:0001321)1.61691840
159Self-mutilation (HP:0000742)1.61145592
160Hypokinesia (HP:0002375)1.59483138
161Ulnar bowing (HP:0003031)1.58107474
162Abnormality of oral frenula (HP:0000190)1.56019407
163Facial cleft (HP:0002006)1.55894961

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.63296754
2CDC73.39159901
3EEF2K3.37013460
4WEE13.28745483
5SMG13.21172353
6PKN22.64439719
7EPHA22.52824366
8TSSK62.49102817
9NEK22.46067788
10NEK12.45266664
11EIF2AK12.42769457
12TESK22.41719120
13CDK122.38967165
14PASK2.24542086
15TRIB32.23013355
16RPS6KB22.18570544
17MAP3K102.15183781
18TTK2.05415493
19BCKDK2.02869298
20PBK1.98062538
21SCYL21.96723922
22IRAK31.84584872
23VRK21.68497621
24NME21.60988156
25FLT31.59821048
26NME11.58516931
27MAP3K81.55319456
28MAP3K91.53683188
29SIK31.50121593
30RPS6KA41.48980385
31CDK71.45350975
32PLK11.44919597
33CDK41.36771814
34ATR1.36327804
35PAK41.35160111
36TLK11.34187673
37KDR1.33548128
38EIF2AK31.32504793
39TTN1.31156099
40STK101.28039737
41AURKB1.27787931
42MAPKAPK31.27025146
43ACVR1B1.24378710
44DYRK31.23620703
45NTRK11.21183503
46ERN11.19058978
47ALK1.16994931
48TESK11.14952245
49CHEK11.14408045
50AURKA1.13718439
51BCR1.13674753
52MTOR1.13113731
53CDK81.12285291
54TGFBR11.12252463
55SRPK11.11432207
56LRRK21.08177565
57TRIM281.07492086
58ARAF1.06839009
59BRSK20.99633770
60MAP2K30.97601311
61PRPF4B0.97461031
62LATS20.95659271
63PLK30.95211700
64CHEK20.94910333
65BRAF0.90259430
66ERBB40.89071139
67BRD40.87243450
68CDK20.81898949
69PDK40.80801818
70PDK30.80801818
71KSR20.80134456
72LMTK20.78848228
73SIK10.77695466
74PDGFRA0.76948245
75PIM20.76281345
76BRSK10.75808299
77PAK10.71597204
78ICK0.71382511
79ATM0.68154502
80CLK10.67408006
81PAK20.67316702
82MST1R0.67299455
83CDK140.67160201
84CDK180.65939727
85CDK60.65725272
86DAPK10.65306013
87STK40.64505204
88CDK11A0.64487617
89AKT20.63351503
90PTK60.63309058
91GRK60.62653221
92CDK150.62194399
93FGFR10.61663052
94PLK40.61378045
95PNCK0.61020451
96CSNK2A20.60720429
97MAP3K110.60466734
98PRKCI0.59530845
99DYRK20.57797957
100TAF10.56566785
101ZAP700.56361492
102LATS10.56022096
103RAF10.55892361
104KSR10.53946914
105CAMK1D0.53702582
106CSNK1G30.53485106
107CDK10.51599458
108MELK0.51583729
109STK160.51561001
110CSNK1E0.51474708
111PRKD30.51079189
112PIM10.50411708
113CSNK1A1L0.49125153
114MET0.46075119
115MAPK110.43131223
116EIF2AK20.41615263
117TAOK20.41550790
118CSNK2A10.40460928
119VRK10.40391956
120LIMK10.40162699
121CDK90.39490830
122ZAK0.38371454
123MAP3K30.38310825
124PDK20.37698564
125PRKDC0.36800425
126BMX0.36365101
127MAP2K20.35853433
128ILK0.34685900
129FGFR40.34518084
130PTK20.32087231
131MKNK10.31507241
132RPS6KA10.31133956
133MAP4K10.30938284
134CSNK1D0.27395741
135STK30.26054211
136RPS6KB10.25612264

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.25009426
2One carbon pool by folate_Homo sapiens_hsa006703.89876736
3Mismatch repair_Homo sapiens_hsa034303.73111972
4* Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.59438193
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.24927924
6RNA transport_Homo sapiens_hsa030133.04466584
7Spliceosome_Homo sapiens_hsa030402.76146191
8Base excision repair_Homo sapiens_hsa034102.59114118
9Proteasome_Homo sapiens_hsa030502.57507023
10Ribosome_Homo sapiens_hsa030102.23816348
11Nucleotide excision repair_Homo sapiens_hsa034202.22325181
12Biosynthesis of amino acids_Homo sapiens_hsa012302.09012896
13Cell cycle_Homo sapiens_hsa041102.06645017
142-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.98463050
15RNA polymerase_Homo sapiens_hsa030201.97104370
16Homologous recombination_Homo sapiens_hsa034401.87135828
17Cyanoamino acid metabolism_Homo sapiens_hsa004601.86780737
18Pyrimidine metabolism_Homo sapiens_hsa002401.72542699
19Cysteine and methionine metabolism_Homo sapiens_hsa002701.65808260
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.64433745
21Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.55860009
22Carbon metabolism_Homo sapiens_hsa012001.54288675
23mRNA surveillance pathway_Homo sapiens_hsa030151.52943974
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.50724070
25* Selenocompound metabolism_Homo sapiens_hsa004501.37093760
26Steroid biosynthesis_Homo sapiens_hsa001001.34197601
27Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.33277241
28Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.27186251
29p53 signaling pathway_Homo sapiens_hsa041151.26733919
30Folate biosynthesis_Homo sapiens_hsa007901.24857792
31RNA degradation_Homo sapiens_hsa030181.22255897
32Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.22169749
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.20025324
34Non-homologous end-joining_Homo sapiens_hsa034501.18590831
35Sulfur relay system_Homo sapiens_hsa041221.17724609
36Pentose phosphate pathway_Homo sapiens_hsa000301.17578300
37Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.09659072
38Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.07330694
39Fanconi anemia pathway_Homo sapiens_hsa034601.05888418
40Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.02199705
41Systemic lupus erythematosus_Homo sapiens_hsa053220.99951135
42Viral carcinogenesis_Homo sapiens_hsa052030.95611076
43Fatty acid elongation_Homo sapiens_hsa000620.95387429
44Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.94997748
45Pyruvate metabolism_Homo sapiens_hsa006200.89687659
46Epstein-Barr virus infection_Homo sapiens_hsa051690.89258689
47Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.89167678
48Vitamin B6 metabolism_Homo sapiens_hsa007500.88723366
49Vibrio cholerae infection_Homo sapiens_hsa051100.86810812
50Central carbon metabolism in cancer_Homo sapiens_hsa052300.83202255
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.81898972
52Basal transcription factors_Homo sapiens_hsa030220.79702379
53Nitrogen metabolism_Homo sapiens_hsa009100.78382588
54Fructose and mannose metabolism_Homo sapiens_hsa000510.76719571
55Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73129151
56Antigen processing and presentation_Homo sapiens_hsa046120.72848112
57Fat digestion and absorption_Homo sapiens_hsa049750.71760846
58Purine metabolism_Homo sapiens_hsa002300.67020873
59Arginine biosynthesis_Homo sapiens_hsa002200.65835957
60Shigellosis_Homo sapiens_hsa051310.64471850
61Thyroid cancer_Homo sapiens_hsa052160.63213353
62Galactose metabolism_Homo sapiens_hsa000520.62606492
63Lysine degradation_Homo sapiens_hsa003100.62522505
64Bladder cancer_Homo sapiens_hsa052190.62300160
65HTLV-I infection_Homo sapiens_hsa051660.61909304
66mTOR signaling pathway_Homo sapiens_hsa041500.61030778
67Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60850065
68Oocyte meiosis_Homo sapiens_hsa041140.59673450
69Arginine and proline metabolism_Homo sapiens_hsa003300.59569682
70Non-small cell lung cancer_Homo sapiens_hsa052230.59548199
71Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59254054
72Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.59005553
73Pancreatic cancer_Homo sapiens_hsa052120.57386043
74N-Glycan biosynthesis_Homo sapiens_hsa005100.57186729
75Glutathione metabolism_Homo sapiens_hsa004800.55598449
76Small cell lung cancer_Homo sapiens_hsa052220.53935799
77Prostate cancer_Homo sapiens_hsa052150.53919557
78MicroRNAs in cancer_Homo sapiens_hsa052060.53105869
79Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.50086489
80Endometrial cancer_Homo sapiens_hsa052130.48500403
81Hippo signaling pathway_Homo sapiens_hsa043900.46589765
82Legionellosis_Homo sapiens_hsa051340.45875613
83Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.45513481
84Longevity regulating pathway - mammal_Homo sapiens_hsa042110.44920977
85Fatty acid degradation_Homo sapiens_hsa000710.43744595
86Hepatitis B_Homo sapiens_hsa051610.43003341
87Glioma_Homo sapiens_hsa052140.42834791
88Propanoate metabolism_Homo sapiens_hsa006400.42237448
89Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42210375
90Protein export_Homo sapiens_hsa030600.40657711
91Notch signaling pathway_Homo sapiens_hsa043300.40619101
92Herpes simplex infection_Homo sapiens_hsa051680.37483055
93HIF-1 signaling pathway_Homo sapiens_hsa040660.36674601
94AMPK signaling pathway_Homo sapiens_hsa041520.36590171
95ErbB signaling pathway_Homo sapiens_hsa040120.36437865
96Basal cell carcinoma_Homo sapiens_hsa052170.36293224
97Chronic myeloid leukemia_Homo sapiens_hsa052200.34479677
98Insulin signaling pathway_Homo sapiens_hsa049100.34296696
99Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.33352480
100Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.31101760
101TGF-beta signaling pathway_Homo sapiens_hsa043500.31018422
102Melanoma_Homo sapiens_hsa052180.30625707
103Colorectal cancer_Homo sapiens_hsa052100.30121232
104Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28958856
105Apoptosis_Homo sapiens_hsa042100.28682602
106Tryptophan metabolism_Homo sapiens_hsa003800.28495497
107Primary bile acid biosynthesis_Homo sapiens_hsa001200.28392202
108Huntingtons disease_Homo sapiens_hsa050160.27102705
109Adherens junction_Homo sapiens_hsa045200.26640951
110Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.26465402
111Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.25870560
112Proteoglycans in cancer_Homo sapiens_hsa052050.25664195
113Inositol phosphate metabolism_Homo sapiens_hsa005620.25546789
114Neurotrophin signaling pathway_Homo sapiens_hsa047220.23265886
115Maturity onset diabetes of the young_Homo sapiens_hsa049500.23104096
116Renin-angiotensin system_Homo sapiens_hsa046140.22496011
117Metabolic pathways_Homo sapiens_hsa011000.21381613
118Acute myeloid leukemia_Homo sapiens_hsa052210.21271145
119Alcoholism_Homo sapiens_hsa050340.19075527
120Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.18315241
121Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.18115456
122Glucagon signaling pathway_Homo sapiens_hsa049220.17079040
123Tight junction_Homo sapiens_hsa045300.16023265
124beta-Alanine metabolism_Homo sapiens_hsa004100.15833308
125Fatty acid metabolism_Homo sapiens_hsa012120.15831320

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