MBOAT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hemidesmosome assembly (GO:0031581)3.87991667
2presynaptic membrane assembly (GO:0097105)3.85003510
3presynaptic membrane organization (GO:0097090)3.70574159
4postsynaptic membrane organization (GO:0001941)3.47958284
5COPI coating of Golgi vesicle (GO:0048205)3.47574226
6Golgi transport vesicle coating (GO:0048200)3.47574226
7negative regulation of neurotransmitter transport (GO:0051589)3.45632364
8iron ion import (GO:0097286)3.41255696
9negative regulation of neurotransmitter secretion (GO:0046929)3.32073768
10neuron recognition (GO:0008038)3.29073189
11axon ensheathment in central nervous system (GO:0032291)3.28466029
12central nervous system myelination (GO:0022010)3.28466029
13establishment of skin barrier (GO:0061436)3.24792608
14response to pheromone (GO:0019236)3.23439488
15pyrimidine nucleobase catabolic process (GO:0006208)3.20606027
16establishment of nucleus localization (GO:0040023)3.20533633
17protoporphyrinogen IX metabolic process (GO:0046501)3.19191474
18amino acid import (GO:0043090)3.18361049
19keratinization (GO:0031424)3.12517755
20glandular epithelial cell differentiation (GO:0002067)3.11391861
21peptide hormone processing (GO:0016486)3.08312994
22regulation of water loss via skin (GO:0033561)3.08034146
23cell communication by electrical coupling (GO:0010644)3.07499917
24calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.03268711
25type B pancreatic cell development (GO:0003323)3.00792623
26synaptic vesicle maturation (GO:0016188)2.98487434
27desmosome organization (GO:0002934)2.91462165
28L-amino acid import (GO:0043092)2.88936430
29ionotropic glutamate receptor signaling pathway (GO:0035235)2.88532251
30startle response (GO:0001964)2.88298849
31glandular epithelial cell development (GO:0002068)2.86340582
32regulation of synaptic vesicle exocytosis (GO:2000300)2.85560509
33nitric oxide mediated signal transduction (GO:0007263)2.85058892
34endocrine pancreas development (GO:0031018)2.82079510
35synapse assembly (GO:0007416)2.81140746
36C4-dicarboxylate transport (GO:0015740)2.75728522
37detection of calcium ion (GO:0005513)2.75294486
38long-chain fatty acid biosynthetic process (GO:0042759)2.74960265
39establishment of planar polarity (GO:0001736)2.72821015
40establishment of tissue polarity (GO:0007164)2.72821015
41astrocyte differentiation (GO:0048708)2.71004639
42positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.64844075
43nerve growth factor signaling pathway (GO:0038180)2.64033640
44regulation of short-term neuronal synaptic plasticity (GO:0048172)2.62599174
45gamma-aminobutyric acid transport (GO:0015812)2.62142547
46retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.61271658
47positive regulation of dendritic spine morphogenesis (GO:0061003)2.60255282
48regulation of synaptic vesicle transport (GO:1902803)2.60089312
49neuronal ion channel clustering (GO:0045161)2.59189944
50import into cell (GO:0098657)2.56920512
51mechanosensory behavior (GO:0007638)2.56313902
52dendritic spine morphogenesis (GO:0060997)2.52579543
53retinal ganglion cell axon guidance (GO:0031290)2.51823689
54multicellular organismal water homeostasis (GO:0050891)2.51766930
55auditory behavior (GO:0031223)2.51484494
56chemosensory behavior (GO:0007635)2.50559952
57protein localization to synapse (GO:0035418)2.49268408
58clathrin coat assembly (GO:0048268)2.49239804
59neuronal action potential propagation (GO:0019227)2.49215041
60regulation of axon guidance (GO:1902667)2.48121393
61photoreceptor cell differentiation (GO:0046530)2.47642487
62eye photoreceptor cell differentiation (GO:0001754)2.47642487
63nucleobase catabolic process (GO:0046113)2.47439107
64organelle transport along microtubule (GO:0072384)2.46500468
65response to methylmercury (GO:0051597)2.46091535
66oligodendrocyte differentiation (GO:0048709)2.45862910
67cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.45764936
68synaptic vesicle endocytosis (GO:0048488)2.45460005
69axon extension (GO:0048675)2.45403703
70positive regulation of meiosis (GO:0045836)2.45202864
71positive regulation of meiotic cell cycle (GO:0051446)2.45066949
72glutamate receptor signaling pathway (GO:0007215)2.44880829
73establishment of mitochondrion localization (GO:0051654)2.43334561
74glutamate secretion (GO:0014047)2.42248596
75response to misfolded protein (GO:0051788)2.40966194
76central nervous system neuron axonogenesis (GO:0021955)2.40867241
77central nervous system projection neuron axonogenesis (GO:0021952)2.40389078
78cell-cell junction maintenance (GO:0045217)2.38883285
79neurotransmitter uptake (GO:0001504)2.38827135
80insulin secretion (GO:0030073)2.38808190
81cellular potassium ion homeostasis (GO:0030007)2.38479208
82synapse organization (GO:0050808)2.37741814
83somite development (GO:0061053)2.37285849
84protoporphyrinogen IX biosynthetic process (GO:0006782)2.36381537
85locomotory exploration behavior (GO:0035641)2.36335884
86ear development (GO:0043583)2.35573510
87layer formation in cerebral cortex (GO:0021819)2.35522982
88behavioral response to cocaine (GO:0048148)2.34308287
89transmission of nerve impulse (GO:0019226)2.34172462
90negative regulation of potassium ion transmembrane transport (GO:1901380)2.34001063
91regulation of cAMP-dependent protein kinase activity (GO:2000479)2.33992178
92negative regulation of glial cell differentiation (GO:0045686)2.33052346
93positive regulation of synapse assembly (GO:0051965)2.32986967
94negative regulation of keratinocyte proliferation (GO:0010839)2.32965547
95regulation of axon extension involved in axon guidance (GO:0048841)2.32930991
96sodium ion export (GO:0071436)2.31969842
97response to auditory stimulus (GO:0010996)2.31545182
98axonogenesis (GO:0007409)2.31295352
99negative regulation of insulin secretion (GO:0046676)2.30574787
100potassium ion homeostasis (GO:0055075)2.30146270
101response to redox state (GO:0051775)2.29934824
102positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.29724587
103membrane assembly (GO:0071709)2.29377454
104positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.29307685
105cerebral cortex radially oriented cell migration (GO:0021799)2.29171328
106asymmetric protein localization (GO:0008105)2.28857431
107synaptic transmission, glutamatergic (GO:0035249)2.28678056
108regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.28612726
109cranial nerve development (GO:0021545)2.28403969
110columnar/cuboidal epithelial cell development (GO:0002066)2.28078002
111regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.27793607
112negative regulation of dendrite morphogenesis (GO:0050774)2.27783792
113regulation of dendritic spine morphogenesis (GO:0061001)2.27532203
114lens fiber cell development (GO:0070307)2.26842540
115negative regulation of astrocyte differentiation (GO:0048712)2.26541342
116limb bud formation (GO:0060174)2.26343342
117cerebellar Purkinje cell differentiation (GO:0021702)2.26243473
118regulation of neuron projection regeneration (GO:0070570)2.24749069
119regulation of axon regeneration (GO:0048679)2.24749069
120positive regulation of neurological system process (GO:0031646)2.24310514
121maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.23274177
122apical protein localization (GO:0045176)2.23094707
123cell differentiation in hindbrain (GO:0021533)2.22580303
124cochlea development (GO:0090102)2.22523167
125vocalization behavior (GO:0071625)2.22407416
126atrial cardiac muscle cell action potential (GO:0086014)2.22239353
127intraciliary transport (GO:0042073)2.21567503
128cardiac right ventricle morphogenesis (GO:0003215)2.21511304
129protein maturation by protein folding (GO:0022417)2.21243013
130dendritic spine organization (GO:0097061)2.21180884
131keratinocyte proliferation (GO:0043616)2.21138711
132positive regulation of insulin secretion (GO:0032024)2.21040278
133axonal fasciculation (GO:0007413)2.20039702
134regulation of type B pancreatic cell apoptotic process (GO:2000674)2.19985894
135homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.19959685
136membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.19781718
137nonmotile primary cilium assembly (GO:0035058)2.19520309
138calcium-mediated signaling using intracellular calcium source (GO:0035584)2.19466663
139neuron projection extension (GO:1990138)2.19409663
140neuron cell-cell adhesion (GO:0007158)2.18926828
141relaxation of smooth muscle (GO:0044557)2.18920857
142cerebellar granule cell differentiation (GO:0021707)2.18194576
143epithelial cell fate commitment (GO:0072148)2.16864431
144growth hormone secretion (GO:0030252)2.16588020
145negative regulation of smoothened signaling pathway (GO:0045879)2.16298396
146sympathetic nervous system development (GO:0048485)2.15860079
147male sex determination (GO:0030238)2.15483983
148regulation of clathrin-mediated endocytosis (GO:2000369)2.15318552
149negative regulation of dendrite development (GO:2000171)2.15292175
150nucleus localization (GO:0051647)2.15260472
151regulation of insulin secretion (GO:0050796)2.15258014
152neuroblast proliferation (GO:0007405)2.15215451
153convergent extension (GO:0060026)2.15064315
154regulation of branching involved in ureteric bud morphogenesis (GO:0090189)2.14941157
155dendrite morphogenesis (GO:0048813)2.14555937
156magnesium ion transport (GO:0015693)2.14488949
157response to lead ion (GO:0010288)2.14134243
158astrocyte development (GO:0014002)2.13918047
159Sertoli cell development (GO:0060009)2.13541683
160ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.13350988
161L-serine transport (GO:0015825)2.13206767
162dendrite development (GO:0016358)2.12896588
163establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.12143241
164negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.12090818
165ephrin receptor signaling pathway (GO:0048013)2.11919895
166lateral sprouting from an epithelium (GO:0060601)2.11553711
167regulation of development, heterochronic (GO:0040034)2.11501286
168innervation (GO:0060384)2.10697455
169sphingosine metabolic process (GO:0006670)2.10657809
170synaptic vesicle exocytosis (GO:0016079)2.09932946
171regulation of neuronal synaptic plasticity (GO:0048168)2.09894206
172cell communication involved in cardiac conduction (GO:0086065)2.09682003
173peripheral nervous system axon ensheathment (GO:0032292)2.09389167
174myelination in peripheral nervous system (GO:0022011)2.09389167
175regulation of cardioblast differentiation (GO:0051890)2.08629840

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human2.84061381
2RBPJ_22232070_ChIP-Seq_NCS_Mouse2.80830915
3CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.58912139
4GBX2_23144817_ChIP-Seq_PC3_Human2.52121459
5SALL1_21062744_ChIP-ChIP_HESCs_Human2.51077705
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.38138647
7EZH2_27304074_Chip-Seq_ESCs_Mouse2.35841758
8IGF1R_20145208_ChIP-Seq_DFB_Human2.23784091
9TAF15_26573619_Chip-Seq_HEK293_Human2.21708784
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.18124790
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.16898053
12SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.14384421
13JARID2_20064375_ChIP-Seq_MESCs_Mouse2.14374166
14GATA1_22025678_ChIP-Seq_K562_Human2.04581607
15RNF2_27304074_Chip-Seq_ESCs_Mouse2.00205180
16EZH2_27294783_Chip-Seq_ESCs_Mouse1.97870660
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.96077083
18JARID2_20075857_ChIP-Seq_MESCs_Mouse1.92491350
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.88644705
20SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.87227419
21REST_21632747_ChIP-Seq_MESCs_Mouse1.86740216
22ZNF274_21170338_ChIP-Seq_K562_Hela1.86375660
23EZH2_18974828_ChIP-Seq_MESCs_Mouse1.85281669
24RNF2_18974828_ChIP-Seq_MESCs_Mouse1.85281669
25TP63_17297297_ChIP-ChIP_HaCaT_Human1.83729008
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.83532673
27SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.77785616
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.76596709
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.73462925
30WT1_19549856_ChIP-ChIP_CCG9911_Human1.73141661
31EWS_26573619_Chip-Seq_HEK293_Human1.66231545
32NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.65624118
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.59741078
34HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.57831861
35DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.55880242
36BMI1_23680149_ChIP-Seq_NPCS_Mouse1.55004851
37TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.52708718
38OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.51161452
39BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.50279679
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.49111545
41FOXM1_26456572_ChIP-Seq_MCF-7_Human1.48972836
42TP53_16413492_ChIP-PET_HCT116_Human1.48066016
43RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.44764042
44NRF2_20460467_ChIP-Seq_MEFs_Mouse1.42719132
45NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.42719132
46ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.41558891
47REST_18959480_ChIP-ChIP_MESCs_Mouse1.41173362
48CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.39779202
49OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37241237
50RNF2_27304074_Chip-Seq_NSC_Mouse1.33994250
51AR_21572438_ChIP-Seq_LNCaP_Human1.33677629
52ARNT_22903824_ChIP-Seq_MCF-7_Human1.32734714
53POU5F1_16153702_ChIP-ChIP_HESCs_Human1.32240421
54CTBP1_25329375_ChIP-Seq_LNCAP_Human1.32217867
55ER_23166858_ChIP-Seq_MCF-7_Human1.31995838
56PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.31853665
57AHR_22903824_ChIP-Seq_MCF-7_Human1.31513505
58SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.30935306
59ZNF263_19887448_ChIP-Seq_K562_Human1.29649642
60TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.27159065
61PIAS1_25552417_ChIP-Seq_VCAP_Human1.26902113
62PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.25297742
63TCF4_23295773_ChIP-Seq_U87_Human1.25180180
64PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.24790681
65STAT6_21828071_ChIP-Seq_BEAS2B_Human1.24764253
66KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.23655991
67VDR_22108803_ChIP-Seq_LS180_Human1.23277320
68* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21940762
69TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21002641
70RARB_27405468_Chip-Seq_BRAIN_Mouse1.19418500
71CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.19221569
72SOX9_26525672_Chip-Seq_HEART_Mouse1.19066682
73RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.18468222
74TP53_18474530_ChIP-ChIP_U2OS_Human1.17477927
75ZNF217_24962896_ChIP-Seq_MCF-7_Human1.16681374
76RING1B_27294783_Chip-Seq_ESCs_Mouse1.16432697
77DROSHA_22980978_ChIP-Seq_HELA_Human1.16186824
78* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15585938
79TAL1_26923725_Chip-Seq_HPCs_Mouse1.15454065
80JUN_21703547_ChIP-Seq_K562_Human1.14846182
81CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14570479
82EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14314125
83E2F1_18555785_Chip-Seq_ESCs_Mouse1.12809599
84RING1B_27294783_Chip-Seq_NPCs_Mouse1.12318520
85* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.12212570
86SMAD3_21741376_ChIP-Seq_EPCs_Human1.11296088
87SMAD3_21741376_ChIP-Seq_ESCs_Human1.10930979
88SMAD_19615063_ChIP-ChIP_OVARY_Human1.10249850
89SMAD4_21799915_ChIP-Seq_A2780_Human1.09394448
90CTNNB1_20460455_ChIP-Seq_HCT116_Human1.09107433
91* STAT3_23295773_ChIP-Seq_U87_Human1.08827379
92CMYC_18555785_Chip-Seq_ESCs_Mouse1.08394058
93* AR_21909140_ChIP-Seq_LNCAP_Human1.07932833
94P53_22387025_ChIP-Seq_ESCs_Mouse1.06140769
95EP300_21415370_ChIP-Seq_HL-1_Mouse1.05719634
96ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.05329516
97AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.05072959
98ZFP57_27257070_Chip-Seq_ESCs_Mouse1.04921452
99HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.04751953
100UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04582446
101* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03419803
102TBX3_20139965_ChIP-Seq_MESCs_Mouse1.02525110
103TBX3_20139965_ChIP-Seq_ESCs_Mouse1.02494213
104YAP1_20516196_ChIP-Seq_MESCs_Mouse1.02213904
105RUNX2_22187159_ChIP-Seq_PCA_Human1.01686549
106P300_19829295_ChIP-Seq_ESCs_Human1.01448840
107* TP63_23658742_ChIP-Seq_EP156T_Human1.00571907
108* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99433849
109SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.99065954
110POU3F2_20337985_ChIP-ChIP_501MEL_Human0.97808768
111SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97210122
112TP53_20018659_ChIP-ChIP_R1E_Mouse0.96790495
113* SOX2_21211035_ChIP-Seq_LN229_Gbm0.96248852
114WT1_25993318_ChIP-Seq_PODOCYTE_Human0.96169664
115TET1_21490601_ChIP-Seq_MESCs_Mouse0.93552151
116AR_25329375_ChIP-Seq_VCAP_Human0.91792893
117ISL1_27105846_Chip-Seq_CPCs_Mouse0.91400190
118* AR_19668381_ChIP-Seq_PC3_Human0.90969801
119TOP2B_26459242_ChIP-Seq_MCF-7_Human0.90324575
120FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.89432964
121CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.89197801
122P53_22127205_ChIP-Seq_FIBROBLAST_Human0.88793571
123LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88344538
124LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.87620803
125GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.87149121
126* TCF4_18268006_ChIP-ChIP_LS174T_Human0.86735227
127GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85625994
128TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.85353966
129FUS_26573619_Chip-Seq_HEK293_Human0.84293951
130NANOG_18555785_Chip-Seq_ESCs_Mouse0.83668940
131REST_19997604_ChIP-ChIP_NEURONS_Mouse0.83633207
132* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83077989
133* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.82749773
134TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.82628029
135SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.82528832
136POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.82498473
137CDX2_19796622_ChIP-Seq_MESCs_Mouse0.82287940
138RXR_22108803_ChIP-Seq_LS180_Human0.82187283
139STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.81697219
140ESR1_21235772_ChIP-Seq_MCF-7_Human0.81325935

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004147_increased_porphyrin_level2.69166590
2MP0009780_abnormal_chondrocyte_physiolo2.59836931
3MP0000569_abnormal_digit_pigmentation2.54986618
4MP0001984_abnormal_olfaction2.31402345
5MP0003283_abnormal_digestive_organ2.25449844
6MP0003941_abnormal_skin_development2.20632049
7MP0004885_abnormal_endolymph2.19366371
8MP0003122_maternal_imprinting2.16727176
9MP0004270_analgesia2.14660604
10MP0005646_abnormal_pituitary_gland2.00774224
11MP0002796_impaired_skin_barrier1.98706736
12MP0002735_abnormal_chemical_nociception1.96471122
13MP0002909_abnormal_adrenal_gland1.96060008
14MP0003656_abnormal_erythrocyte_physiolo1.95371062
15MP0010386_abnormal_urinary_bladder1.95357985
16MP0006072_abnormal_retinal_apoptosis1.92537768
17MP0005645_abnormal_hypothalamus_physiol1.88299901
18MP0004043_abnormal_pH_regulation1.87157529
19MP0001299_abnormal_eye_distance/1.82783361
20MP0002234_abnormal_pharynx_morphology1.82453720
21MP0002638_abnormal_pupillary_reflex1.79889825
22MP0000566_synostosis1.76061640
23MP0000427_abnormal_hair_cycle1.71634194
24MP0004859_abnormal_synaptic_plasticity1.68675892
25MP0001502_abnormal_circadian_rhythm1.63653853
26MP0001188_hyperpigmentation1.63372765
27MP0002877_abnormal_melanocyte_morpholog1.63284189
28MP0003880_abnormal_central_pattern1.57863977
29MP0002009_preneoplasia1.54087840
30MP0000013_abnormal_adipose_tissue1.52672983
31MP0000631_abnormal_neuroendocrine_gland1.51755131
32MP0005248_abnormal_Harderian_gland1.51352619
33MP0003329_amyloid_beta_deposits1.47816045
34MP0000678_abnormal_parathyroid_gland1.47747089
35MP0010234_abnormal_vibrissa_follicle1.47098380
36MP0003787_abnormal_imprinting1.45536269
37MP0005275_abnormal_skin_tensile1.45216924
38MP0000778_abnormal_nervous_system1.44288392
39MP0005409_darkened_coat_color1.42922455
40MP0005379_endocrine/exocrine_gland_phen1.42774537
41MP0005171_absent_coat_pigmentation1.41155620
42MP0003136_yellow_coat_color1.38469245
43MP0003635_abnormal_synaptic_transmissio1.36890879
44MP0002734_abnormal_mechanical_nocicepti1.34541330
45MP0002653_abnormal_ependyma_morphology1.33900313
46MP0010030_abnormal_orbit_morphology1.31129388
47MP0002736_abnormal_nociception_after1.30451766
48MP0001486_abnormal_startle_reflex1.30202415
49MP0000462_abnormal_digestive_system1.29016566
50MP0008789_abnormal_olfactory_epithelium1.28114982
51MP0001485_abnormal_pinna_reflex1.28102369
52MP0004811_abnormal_neuron_physiology1.27508763
53MP0005394_taste/olfaction_phenotype1.27413828
54MP0005499_abnormal_olfactory_system1.27413828
55MP0001968_abnormal_touch/_nociception1.26237672
56MP0003183_abnormal_peptide_metabolism1.21290030
57MP0003121_genomic_imprinting1.20627370
58MP0006292_abnormal_olfactory_placode1.18926572
59MP0003634_abnormal_glial_cell1.17833305
60MP0002557_abnormal_social/conspecific_i1.17448883
61MP0003890_abnormal_embryonic-extraembry1.17319023
62MP0002063_abnormal_learning/memory/cond1.16646539
63MP0001944_abnormal_pancreas_morphology1.14456718
64MP0002098_abnormal_vibrissa_morphology1.14380031
65MP0000049_abnormal_middle_ear1.12866612
66MP0000955_abnormal_spinal_cord1.12743225
67MP0000762_abnormal_tongue_morphology1.09612709
68MP0003705_abnormal_hypodermis_morpholog1.07790472
69MP0000377_abnormal_hair_follicle1.07628615
70MP0002184_abnormal_innervation1.07451575
71MP0009745_abnormal_behavioral_response1.06974815
72MP0003315_abnormal_perineum_morphology1.06727032
73MP0003119_abnormal_digestive_system1.06675188
74MP0003861_abnormal_nervous_system1.06665918
75MP0005253_abnormal_eye_physiology1.06493361
76MP0001970_abnormal_pain_threshold1.06106749
77MP0003632_abnormal_nervous_system1.05641679
78MP0010771_integument_phenotype1.05362361
79MP0004858_abnormal_nervous_system1.04702042
80MP0009384_cardiac_valve_regurgitation1.02936261
81MP0002272_abnormal_nervous_system1.02195682
82MP0000579_abnormal_nail_morphology1.01689494
83MP0002938_white_spotting1.01004474
84MP0001177_atelectasis1.00914969
85MP0005423_abnormal_somatic_nervous1.00850693
86MP0002572_abnormal_emotion/affect_behav1.00846990
87MP0001529_abnormal_vocalization1.00810644
88MP0006276_abnormal_autonomic_nervous1.00359273
89MP0002733_abnormal_thermal_nociception0.97675951
90MP0000537_abnormal_urethra_morphology0.95702474
91MP0002822_catalepsy0.95632839
92MP0005501_abnormal_skin_physiology0.95177584
93MP0005386_behavior/neurological_phenoty0.94588350
94MP0004924_abnormal_behavior0.94588350
95MP0000467_abnormal_esophagus_morphology0.94520569
96MP0002882_abnormal_neuron_morphology0.92751514
97MP0002177_abnormal_outer_ear0.92130570
98MP0000026_abnormal_inner_ear0.91934159
99MP0008995_early_reproductive_senescence0.91497190
100MP0000647_abnormal_sebaceous_gland0.91448291
101MP0002693_abnormal_pancreas_physiology0.89970484
102MP0002064_seizures0.89932376
103MP0010678_abnormal_skin_adnexa0.89201753
104MP0002697_abnormal_eye_size0.88994612
105MP0009046_muscle_twitch0.87745233
106MP0002233_abnormal_nose_morphology0.87190273
107MP0002751_abnormal_autonomic_nervous0.87128622
108MP0008877_abnormal_DNA_methylation0.86633603
109MP0003937_abnormal_limbs/digits/tail_de0.85270988
110MP0002067_abnormal_sensory_capabilities0.85074379
111MP0000534_abnormal_ureter_morphology0.84781445
112MP0002116_abnormal_craniofacial_bone0.84766673
113MP0003935_abnormal_craniofacial_develop0.84023171
114MP0002060_abnormal_skin_morphology0.83843147
115MP0002095_abnormal_skin_pigmentation0.82500692
116MP0005187_abnormal_penis_morphology0.82478864
117MP0003755_abnormal_palate_morphology0.82431495
118MP0002152_abnormal_brain_morphology0.82164202
119MP0001963_abnormal_hearing_physiology0.82101468
120MP0010352_gastrointestinal_tract_polyps0.81192022
121MP0005451_abnormal_body_composition0.81138865
122MP0004145_abnormal_muscle_electrophysio0.80340515
123MP0003878_abnormal_ear_physiology0.80144880
124MP0005377_hearing/vestibular/ear_phenot0.80144880
125MP0000383_abnormal_hair_follicle0.79699190
126MP0002752_abnormal_somatic_nervous0.79627411
127MP0000428_abnormal_craniofacial_morphol0.78120533
128MP0004742_abnormal_vestibular_system0.77537021
129MP0001270_distended_abdomen0.76948877
130MP0003631_nervous_system_phenotype0.76415314
131MP0000372_irregular_coat_pigmentation0.76013895
132MP0008569_lethality_at_weaning0.75495552
133MP0005551_abnormal_eye_electrophysiolog0.74759306
134MP0003385_abnormal_body_wall0.73951036
135MP0001216_abnormal_epidermal_layer0.73808092
136MP0002081_perinatal_lethality0.73544712
137MP0009053_abnormal_anal_canal0.73284224
138MP0003942_abnormal_urinary_system0.72875713

Predicted human phenotypes

RankGene SetZ-score
1Onycholysis (HP:0001806)3.77951722
2Papillary thyroid carcinoma (HP:0002895)3.40224480
3Aplasia/hypoplasia of the uterus (HP:0008684)3.30290144
4Megalencephaly (HP:0001355)3.25085893
5Abnormality of the heme biosynthetic pathway (HP:0010472)3.20900150
6Split foot (HP:0001839)3.16640864
7Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.16166178
8Hypoplastic pelvis (HP:0008839)3.09818921
9Hypoplastic labia majora (HP:0000059)2.95717363
10Aplasia involving bones of the upper limbs (HP:0009823)2.78360302
11Aplasia of the phalanges of the hand (HP:0009802)2.78360302
12Aplasia involving bones of the extremities (HP:0009825)2.78360302
13Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.77029699
14Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.76637375
15Degeneration of the lateral corticospinal tracts (HP:0002314)2.76637375
16Atrophic scars (HP:0001075)2.71194610
17Plantar hyperkeratosis (HP:0007556)2.68860395
18Abnormality of the labia majora (HP:0012881)2.67957959
19Thyroid carcinoma (HP:0002890)2.67341586
20Abnormality of the corticospinal tract (HP:0002492)2.64043025
21Insidious onset (HP:0003587)2.63179262
22Termporal pattern (HP:0011008)2.63179262
23Hypoplasia of the uterus (HP:0000013)2.63032654
24Labial hypoplasia (HP:0000066)2.58168632
25Fragile nails (HP:0001808)2.57814219
26Abnormal pancreas size (HP:0012094)2.57731148
27Abnormal sex determination (HP:0012244)2.57548259
28Sex reversal (HP:0012245)2.57548259
29Poikilocytosis (HP:0004447)2.57325818
30Symptomatic seizures (HP:0011145)2.55380288
31Volvulus (HP:0002580)2.50737519
32Neurofibrillary tangles (HP:0002185)2.50412639
33Drooling (HP:0002307)2.50189435
34Anteriorly placed anus (HP:0001545)2.48950733
35Milia (HP:0001056)2.47727333
36Hypoglycemic seizures (HP:0002173)2.47480425
37Hyperinsulinemic hypoglycemia (HP:0000825)2.46914985
38Abnormality of calcium-phosphate metabolism (HP:0100530)2.43386102
39Hypoplastic female external genitalia (HP:0012815)2.39703859
40Palmar hyperkeratosis (HP:0010765)2.36247269
41Congenital ichthyosiform erythroderma (HP:0007431)2.33224975
42Vertebral arch anomaly (HP:0008438)2.29841529
43Hyperventilation (HP:0002883)2.28153076
44Palmoplantar hyperkeratosis (HP:0000972)2.27578804
45Hemiparesis (HP:0001269)2.24727496
46Ankyloglossia (HP:0010296)2.23934612
47Excessive salivation (HP:0003781)2.19226807
48Insomnia (HP:0100785)2.18165416
49Germ cell neoplasia (HP:0100728)2.14946956
50Ankle clonus (HP:0011448)2.14620725
51Large for gestational age (HP:0001520)2.10987602
52Humeroradial synostosis (HP:0003041)2.09705859
53Synostosis involving the elbow (HP:0003938)2.09705859
54Oligodactyly (hands) (HP:0001180)2.09609674
55Popliteal pterygium (HP:0009756)2.09288205
56Cutaneous syndactyly (HP:0012725)2.08818540
57Curly hair (HP:0002212)2.08588593
58Pheochromocytoma (HP:0002666)2.07058014
59Autoamputation (HP:0001218)2.03383133
60Cutaneous finger syndactyly (HP:0010554)1.99514601
61Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.96544413
62Febrile seizures (HP:0002373)1.90516206
63Osteomalacia (HP:0002749)1.90300182
64Polyphagia (HP:0002591)1.89822833
65Fibular aplasia (HP:0002990)1.89773159
66Abnormality of the axillary hair (HP:0100134)1.89294670
67Abnormality of secondary sexual hair (HP:0009888)1.89294670
68Hypotrichosis (HP:0001006)1.88136605
69Insulin-resistant diabetes mellitus (HP:0000831)1.86829490
70Hypochromic microcytic anemia (HP:0004840)1.86597594
71Bifid tongue (HP:0010297)1.86496118
72Delayed epiphyseal ossification (HP:0002663)1.86114762
73Pili torti (HP:0003777)1.85825306
74Exotropia (HP:0000577)1.83794976
75Focal seizures (HP:0007359)1.82809122
76Thick nail (HP:0001805)1.82679490
77Ventricular fibrillation (HP:0001663)1.82515224
78Acanthocytosis (HP:0001927)1.81987433
79Right ventricular cardiomyopathy (HP:0011663)1.80672519
80Supranuclear gaze palsy (HP:0000605)1.80106652
81Hyperglycemia (HP:0003074)1.79464413
82Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.79166663
83Flat capital femoral epiphysis (HP:0003370)1.78507234
84Woolly hair (HP:0002224)1.78426982
85Pterygium (HP:0001059)1.77595213
86Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.77130010
87EEG with generalized epileptiform discharges (HP:0011198)1.76263669
88Abnormality of the astrocytes (HP:0100707)1.76226358
89Astrocytoma (HP:0009592)1.76226358
90Hyperparathyroidism (HP:0000843)1.75612962
91Abnormality of the fovea (HP:0000493)1.74677773
92Absent speech (HP:0001344)1.74618879
93Failure to thrive in infancy (HP:0001531)1.74101446
94Abnormality of the salivary glands (HP:0010286)1.73941454
95Cubitus valgus (HP:0002967)1.73104584
96Medial flaring of the eyebrow (HP:0010747)1.72420461
97Decreased circulating renin level (HP:0003351)1.71824739
98Oligodactyly (HP:0012165)1.70685533
99Epileptiform EEG discharges (HP:0011182)1.70457111
100Arterial tortuosity (HP:0005116)1.70390738
101Lip pit (HP:0100267)1.70327724
102Cerebral inclusion bodies (HP:0100314)1.70046801
103Alopecia of scalp (HP:0002293)1.69912015
104Mixed hearing impairment (HP:0000410)1.69879553
105Natal tooth (HP:0000695)1.68998383
106Postural instability (HP:0002172)1.68991886
107Large earlobe (HP:0009748)1.68723956
108Myokymia (HP:0002411)1.68475066
109Epiphyseal dysplasia (HP:0002656)1.68171121
110Spastic gait (HP:0002064)1.67608368
111Impaired vibration sensation in the lower limbs (HP:0002166)1.67442296
112Maternal diabetes (HP:0009800)1.67358420
113Absent eyebrow (HP:0002223)1.65118632
114Broad-based gait (HP:0002136)1.64439582
115Abnormality of the labia (HP:0000058)1.64238528
116Hypoplasia of the fovea (HP:0007750)1.64210471
117Aplasia/Hypoplasia of the fovea (HP:0008060)1.64210471
118Neoplasm of the thyroid gland (HP:0100031)1.63622813
119Hypsarrhythmia (HP:0002521)1.63247381
120Reticulocytosis (HP:0001923)1.62843665
121Gait imbalance (HP:0002141)1.62493298
122Epileptic encephalopathy (HP:0200134)1.62425861
123Visual hallucinations (HP:0002367)1.62048471
124Increased circulating renin level (HP:0000848)1.61920204
125Cupped ear (HP:0000378)1.61914012
126Morphological abnormality of the pyramidal tract (HP:0002062)1.61343755
127Septo-optic dysplasia (HP:0100842)1.60161855
128Anterior segment dysgenesis (HP:0007700)1.60151173
129Ectopic anus (HP:0004397)1.59736907
130Widely patent fontanelles and sutures (HP:0004492)1.59549692
131Sparse scalp hair (HP:0002209)1.59494366
132Overgrowth (HP:0001548)1.59101105
133Genital tract atresia (HP:0001827)1.59048683
134Urinary urgency (HP:0000012)1.58851551
135Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.58832475
136Hypokalemia (HP:0002900)1.57590153
137Lower limb muscle weakness (HP:0007340)1.57279683
138Glioma (HP:0009733)1.56418722
139Median cleft lip (HP:0000161)1.56234833
140Vaginal atresia (HP:0000148)1.55790698
141Cerebral hypomyelination (HP:0006808)1.55436239
142Abnormality of nail color (HP:0100643)1.54925018
143Pancreatic fibrosis (HP:0100732)1.54869828
144Specific learning disability (HP:0001328)1.54532418
145Chronic bronchitis (HP:0004469)1.54315466
146Genetic anticipation (HP:0003743)1.53770223
147Abnormality of the phalanges of the 5th finger (HP:0004213)1.53340515
148Bladder neoplasm (HP:0009725)1.52566184
149Bladder carcinoma (HP:0002862)1.52566184
150Adrenal hypoplasia (HP:0000835)1.52160415
151Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.52149972
152Dysdiadochokinesis (HP:0002075)1.52120900
153Laryngomalacia (HP:0001601)1.51766050
154Bronchomalacia (HP:0002780)1.51722689
155Limb dystonia (HP:0002451)1.51473830
156Abnormality of chromosome segregation (HP:0002916)1.50592676
157Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.49672759
158Progressive cerebellar ataxia (HP:0002073)1.49583688
159Poor coordination (HP:0002370)1.48961834
160Symphalangism affecting the phalanges of the hand (HP:0009773)1.48361353
161Parakeratosis (HP:0001036)1.48318094
162Focal motor seizures (HP:0011153)1.47845883
163Clonus (HP:0002169)1.47807973
164Neuroendocrine neoplasm (HP:0100634)1.46937108
165Urinary bladder sphincter dysfunction (HP:0002839)1.46922974
166Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.46904844
167Absent eyelashes (HP:0000561)1.46538110
168Long clavicles (HP:0000890)1.46523809
169Long nose (HP:0003189)1.45809640
170Nephrogenic diabetes insipidus (HP:0009806)1.45400570
171Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.45167527
172Progressive neurologic deterioration (HP:0002344)1.45083323
173Exostoses (HP:0100777)1.44936344
174Congenital primary aphakia (HP:0007707)1.44648479
175Anophthalmia (HP:0000528)1.44075925
176Intestinal atresia (HP:0011100)1.43358341
177Aplasia/Hypoplasia involving the pelvis (HP:0009103)1.43043694
178Late onset (HP:0003584)1.41958315
179Action tremor (HP:0002345)1.40137425
180Aplasia/Hypoplasia of the fibula (HP:0006492)1.40125755
181Restlessness (HP:0000711)1.39693372
18211 pairs of ribs (HP:0000878)1.38512097

Predicted kinase interactions (KEA)

RankGene SetZ-score
1INSRR3.46222439
2MARK12.93561952
3PRKD32.64141811
4TNIK2.63359964
5EPHA42.54855713
6PASK2.53702591
7MAPK152.45375651
8MAP3K22.32580413
9BCR2.15556635
10MUSK2.11585028
11NTRK32.05228809
12WNK32.01688902
13PHKG11.80556101
14PHKG21.80556101
15NTRK21.79529333
16PLK21.78484292
17EIF2AK11.77346496
18DYRK21.77039303
19UHMK11.73713345
20PNCK1.70868227
21MET1.65813256
22HIPK21.55716419
23LATS11.55261240
24MAPK131.49511459
25PAK31.43164837
26KSR11.41065448
27PRPF4B1.39946979
28MINK11.34523323
29MAP2K41.34149983
30NTRK11.26836411
31TRIM281.26410250
32MAP3K61.23562463
33LMTK21.23542135
34CAMK1G1.23444594
35IRAK21.22394346
36STK38L1.18567034
37FER1.14482836
38CASK1.14386377
39FRK1.14335953
40DYRK1A1.14000616
41IRAK11.11239790
42PTK2B1.10642053
43MST41.07580885
44RAF11.07230648
45WNK11.06533612
46WNK41.02116725
47SGK2231.01825381
48SGK4941.01825381
49CAMK1D1.01599803
50PAK61.00739693
51ERBB30.99433635
52EPHB20.99183713
53EPHA30.98584040
54STK30.98071887
55CDK50.96597684
56KSR20.95943357
57RPS6KA40.92992991
58BRAF0.92766634
59NEK60.91707010
60DYRK30.90132780
61SGK30.88315868
62MAP3K90.87857632
63MARK20.87658120
64BMPR1B0.86058621
65TAOK10.80015061
66CSNK1G20.79408785
67MAP2K70.77940241
68PTK20.77791062
69PINK10.77578767
70CSNK1G30.76744152
71TYRO30.75823310
72STK390.74254743
73SRPK10.74180429
74CSNK1A1L0.73598360
75MAP2K20.72744088
76PRKCE0.71958091
77MAP3K30.71954606
78RET0.71034342
79MST1R0.71015329
80PRKCG0.70675879
81AKT30.69702364
82STK380.69615735
83CSNK1G10.67875794
84CAMKK20.65997191
85PKN20.65008958
86LIMK10.64768813
87BRSK20.64156653
88LATS20.64009545
89CCNB10.63653778
90MAP3K40.62767704
91CDC42BPA0.62733129
92PRKCI0.62330049
93OXSR10.61919291
94AURKA0.59833687
95SGK10.59700440
96EPHA20.59335098
97DYRK1B0.59205262
98PRKAA10.58325683
99VRK10.57143905
100PLK30.57045671
101ROCK10.56755510
102CDK140.55063244
103PDGFRB0.54949099
104CDK30.54568076
105NME10.53856220
106TRPM70.53826471
107SGK20.53471782
108BMPR20.52531633
109YES10.51926236
110TSSK60.51852302
111ROCK20.50601894
112CDK180.50140539
113BRSK10.49310980
114CAMK2B0.48846728
115PDGFRA0.48686669
116MAPK100.47236067
117ERBB20.47235648
118MAPK90.46908411
119STK110.45891249
120CSNK1A10.44191092
121CHEK20.43628572
122CAMK2A0.43502085
123BRD40.43249296
124STK240.42682376
125SCYL20.42386374
126CDK150.42375363
127BMX0.40969210
128CAMKK10.40003308
129CSNK1E0.36123460
130ADRBK10.35720246
131PRKCZ0.35649200

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049503.94286058
2Protein export_Homo sapiens_hsa030602.86216297
3Insulin secretion_Homo sapiens_hsa049112.53047820
4Circadian rhythm_Homo sapiens_hsa047102.30003038
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.18467103
6Sphingolipid metabolism_Homo sapiens_hsa006002.01511729
7Amphetamine addiction_Homo sapiens_hsa050311.75222110
8Cocaine addiction_Homo sapiens_hsa050301.74386253
9Nicotine addiction_Homo sapiens_hsa050331.72078268
10Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.67174056
11Sulfur metabolism_Homo sapiens_hsa009201.66035158
12Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.64976562
13Hedgehog signaling pathway_Homo sapiens_hsa043401.63221956
14Vibrio cholerae infection_Homo sapiens_hsa051101.59548517
15GABAergic synapse_Homo sapiens_hsa047271.56278312
16Synaptic vesicle cycle_Homo sapiens_hsa047211.52758762
17Steroid biosynthesis_Homo sapiens_hsa001001.47023154
18Basal cell carcinoma_Homo sapiens_hsa052171.45374155
19Axon guidance_Homo sapiens_hsa043601.42164026
20Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.40786460
21Circadian entrainment_Homo sapiens_hsa047131.40371114
22Endometrial cancer_Homo sapiens_hsa052131.39314254
23Ether lipid metabolism_Homo sapiens_hsa005651.38911677
24Long-term potentiation_Homo sapiens_hsa047201.38286833
25alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.35756770
26Serotonergic synapse_Homo sapiens_hsa047261.34834070
27Glutamatergic synapse_Homo sapiens_hsa047241.34536908
28Taste transduction_Homo sapiens_hsa047421.32542103
29Dopaminergic synapse_Homo sapiens_hsa047281.31908758
30Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.27167960
31Regulation of autophagy_Homo sapiens_hsa041401.21482816
32Linoleic acid metabolism_Homo sapiens_hsa005911.21465110
33N-Glycan biosynthesis_Homo sapiens_hsa005101.19034560
34Glioma_Homo sapiens_hsa052141.18790538
35Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.17383287
36Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.17088631
37Melanogenesis_Homo sapiens_hsa049161.15397065
38Collecting duct acid secretion_Homo sapiens_hsa049661.15290672
39Adherens junction_Homo sapiens_hsa045201.12968827
40Wnt signaling pathway_Homo sapiens_hsa043101.12540121
41ECM-receptor interaction_Homo sapiens_hsa045121.12019733
42Olfactory transduction_Homo sapiens_hsa047401.10480231
43Oocyte meiosis_Homo sapiens_hsa041141.09757715
44Hippo signaling pathway_Homo sapiens_hsa043901.06845993
45Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.02498918
46Renin secretion_Homo sapiens_hsa049241.00438589
47Fatty acid biosynthesis_Homo sapiens_hsa000610.99387318
48Inositol phosphate metabolism_Homo sapiens_hsa005620.98827696
49Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97568304
50Pancreatic secretion_Homo sapiens_hsa049720.96301254
51Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.96230698
52Salivary secretion_Homo sapiens_hsa049700.95257581
53Choline metabolism in cancer_Homo sapiens_hsa052310.94836470
54RNA polymerase_Homo sapiens_hsa030200.93294272
55Alcoholism_Homo sapiens_hsa050340.92387021
56SNARE interactions in vesicular transport_Homo sapiens_hsa041300.91899566
57MicroRNAs in cancer_Homo sapiens_hsa052060.90282205
58Type II diabetes mellitus_Homo sapiens_hsa049300.89896447
59Cholinergic synapse_Homo sapiens_hsa047250.89631253
60Tight junction_Homo sapiens_hsa045300.89353209
61Long-term depression_Homo sapiens_hsa047300.89275416
62Aldosterone synthesis and secretion_Homo sapiens_hsa049250.88599591
63Morphine addiction_Homo sapiens_hsa050320.87533578
64mTOR signaling pathway_Homo sapiens_hsa041500.87166304
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.86419490
66Fatty acid elongation_Homo sapiens_hsa000620.83349501
67Cardiac muscle contraction_Homo sapiens_hsa042600.81161772
68Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.81144066
69Non-small cell lung cancer_Homo sapiens_hsa052230.80214814
70Rap1 signaling pathway_Homo sapiens_hsa040150.80206072
71Focal adhesion_Homo sapiens_hsa045100.79961192
72* Glycerophospholipid metabolism_Homo sapiens_hsa005640.79626114
73Lysosome_Homo sapiens_hsa041420.79534292
74Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.78662035
75Glucagon signaling pathway_Homo sapiens_hsa049220.78477148
76Colorectal cancer_Homo sapiens_hsa052100.78198445
77Gap junction_Homo sapiens_hsa045400.77803979
78Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.77691215
79cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77589265
80Gastric acid secretion_Homo sapiens_hsa049710.77213038
81Pancreatic cancer_Homo sapiens_hsa052120.76827763
82Neurotrophin signaling pathway_Homo sapiens_hsa047220.76790086
83Ovarian steroidogenesis_Homo sapiens_hsa049130.75673669
84Melanoma_Homo sapiens_hsa052180.74215889
85Ras signaling pathway_Homo sapiens_hsa040140.73531655
86Chronic myeloid leukemia_Homo sapiens_hsa052200.73073495
87Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72935890
88Estrogen signaling pathway_Homo sapiens_hsa049150.72847165
89Vascular smooth muscle contraction_Homo sapiens_hsa042700.72688414
90VEGF signaling pathway_Homo sapiens_hsa043700.72481739
91Phospholipase D signaling pathway_Homo sapiens_hsa040720.72299573
92Nitrogen metabolism_Homo sapiens_hsa009100.71415308
93Thyroid hormone synthesis_Homo sapiens_hsa049180.70250915
94Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69408411
95Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.69003745
96Platelet activation_Homo sapiens_hsa046110.67961804
97Arachidonic acid metabolism_Homo sapiens_hsa005900.67905806
98cAMP signaling pathway_Homo sapiens_hsa040240.66790876
99Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.66668004
100Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.65256322
101Basal transcription factors_Homo sapiens_hsa030220.65089083
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63277317
103Proteoglycans in cancer_Homo sapiens_hsa052050.62760726
104Prolactin signaling pathway_Homo sapiens_hsa049170.62736770
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.61924506
106Prostate cancer_Homo sapiens_hsa052150.61896729
107AMPK signaling pathway_Homo sapiens_hsa041520.60091943
108Pathways in cancer_Homo sapiens_hsa052000.59570618
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.59314133
110Oxytocin signaling pathway_Homo sapiens_hsa049210.58000575
111Thyroid cancer_Homo sapiens_hsa052160.57963302
112Small cell lung cancer_Homo sapiens_hsa052220.57198478
113Calcium signaling pathway_Homo sapiens_hsa040200.56226148
114ErbB signaling pathway_Homo sapiens_hsa040120.55357455
115GnRH signaling pathway_Homo sapiens_hsa049120.55320506
116Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54920290
117Mineral absorption_Homo sapiens_hsa049780.54667976
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54323757
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53755432
120TGF-beta signaling pathway_Homo sapiens_hsa043500.51730253
121Notch signaling pathway_Homo sapiens_hsa043300.51590349
122Butanoate metabolism_Homo sapiens_hsa006500.50920696
123Renal cell carcinoma_Homo sapiens_hsa052110.48884427
124Dorso-ventral axis formation_Homo sapiens_hsa043200.48392737
125Dilated cardiomyopathy_Homo sapiens_hsa054140.46965183
126Alzheimers disease_Homo sapiens_hsa050100.45654902
127Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.44162080
128Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.44081734
129Sphingolipid signaling pathway_Homo sapiens_hsa040710.43063980
130Phosphatidylinositol signaling system_Homo sapiens_hsa040700.42413439
131Phototransduction_Homo sapiens_hsa047440.41948352
132Other glycan degradation_Homo sapiens_hsa005110.41904674
133Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.41297888
134Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.40321501

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