MBTD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of gene silencing by RNA (GO:0060966)5.43025069
2regulation of posttranscriptional gene silencing (GO:0060147)5.43025069
3regulation of gene silencing by miRNA (GO:0060964)5.43025069
4mitotic sister chromatid cohesion (GO:0007064)5.19715331
5monoubiquitinated protein deubiquitination (GO:0035520)4.55036385
6mitotic metaphase plate congression (GO:0007080)4.54816495
7nuclear pore complex assembly (GO:0051292)4.53279133
8mitotic chromosome condensation (GO:0007076)4.43082589
9kinetochore organization (GO:0051383)4.29073650
10nuclear pore organization (GO:0006999)4.27926209
11histone H3-K36 demethylation (GO:0070544)4.23596920
12metaphase plate congression (GO:0051310)4.17227900
13negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.10687496
14negative regulation of translation, ncRNA-mediated (GO:0040033)4.10687496
15regulation of translation, ncRNA-mediated (GO:0045974)4.10687496
16DNA unwinding involved in DNA replication (GO:0006268)4.08076265
17regulation of sister chromatid cohesion (GO:0007063)4.04298039
18meiotic chromosome segregation (GO:0045132)4.02682648
19kinetochore assembly (GO:0051382)3.98796023
20positive regulation of SMAD protein import into nucleus (GO:0060391)3.96389814
21DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.88029070
22sister chromatid cohesion (GO:0007062)3.85164635
23regulation of RNA export from nucleus (GO:0046831)3.84276340
24regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.79056358
25heterochromatin organization (GO:0070828)3.75787738
26pre-miRNA processing (GO:0031054)3.70953197
27DNA damage response, signal transduction resulting in transcription (GO:0042772)3.70047157
28negative regulation of DNA repair (GO:0045738)3.67810665
29paraxial mesoderm development (GO:0048339)3.61533294
30protein localization to kinetochore (GO:0034501)3.58842659
31DNA topological change (GO:0006265)3.56653067
32protein-DNA complex disassembly (GO:0032986)3.54989130
33nucleosome disassembly (GO:0006337)3.54989130
34regulation of gene silencing (GO:0060968)3.53735450
35establishment of chromosome localization (GO:0051303)3.53430404
36protein localization to chromosome, centromeric region (GO:0071459)3.51755293
37histone H2A monoubiquitination (GO:0035518)3.51300014
38positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.50761337
39positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.50761337
40positive regulation of mitotic sister chromatid separation (GO:1901970)3.50761337
41positive regulation of chromosome segregation (GO:0051984)3.46736230
42maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.46626127
43DNA replication-independent nucleosome organization (GO:0034724)3.46231492
44DNA replication-independent nucleosome assembly (GO:0006336)3.46231492
45negative regulation of histone methylation (GO:0031061)3.44058605
46cytoplasmic mRNA processing body assembly (GO:0033962)3.40654014
47mitotic sister chromatid segregation (GO:0000070)3.39959929
48attachment of spindle microtubules to kinetochore (GO:0008608)3.39576869
49mRNA stabilization (GO:0048255)3.37113548
50RNA stabilization (GO:0043489)3.37113548
51regulation of stem cell maintenance (GO:2000036)3.36856100
52regulation of meiosis I (GO:0060631)3.36049964
53sister chromatid segregation (GO:0000819)3.33626087
54DNA duplex unwinding (GO:0032508)3.33304827
55regulation of histone H3-K4 methylation (GO:0051569)3.32155448
56negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.32037624
57positive regulation of histone methylation (GO:0031062)3.30340465
58histone exchange (GO:0043486)3.29039387
59DNA geometric change (GO:0032392)3.28890400
60regulation of spindle organization (GO:0090224)3.28502957
61regulation of histone methylation (GO:0031060)3.27732843
62mRNA splice site selection (GO:0006376)3.27466312
63chromatin remodeling at centromere (GO:0031055)3.26329325
64protein localization to chromosome (GO:0034502)3.25722838
65negative regulation of DNA-dependent DNA replication (GO:2000104)3.25273114
66histone H3-K9 methylation (GO:0051567)3.25208052
67pore complex assembly (GO:0046931)3.24958611
68CENP-A containing nucleosome assembly (GO:0034080)3.24927936
69phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.24174883
70regulation of histone H3-K9 methylation (GO:0051570)3.23550529
71piRNA metabolic process (GO:0034587)3.22756760
72microtubule depolymerization (GO:0007019)3.22726038
73interkinetic nuclear migration (GO:0022027)3.20512209
74regulation of chromatin silencing (GO:0031935)3.18950992
75centriole replication (GO:0007099)3.18419815
76regulation of chromatin binding (GO:0035561)3.17210172
77positive regulation of histone H3-K4 methylation (GO:0051571)3.16911958
78spindle checkpoint (GO:0031577)3.15648554
79regulation of chromosome segregation (GO:0051983)3.13719091
80definitive hemopoiesis (GO:0060216)3.10316382
81positive regulation of developmental pigmentation (GO:0048087)3.09989216
82regulation of mRNA stability (GO:0043488)3.08816522
83inner cell mass cell proliferation (GO:0001833)3.08287965
84regulation of histone H3-K27 methylation (GO:0061085)3.07075526
85chromatin assembly or disassembly (GO:0006333)3.06457139
86regulation of DNA endoreduplication (GO:0032875)3.06316984
87mitotic nuclear envelope disassembly (GO:0007077)3.02726670
88chromosome segregation (GO:0007059)3.01603155
89gene silencing by RNA (GO:0031047)3.00924647
90ATP-dependent chromatin remodeling (GO:0043044)2.99963711
91protein K6-linked ubiquitination (GO:0085020)2.99401570
92V(D)J recombination (GO:0033151)2.97662882
93regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.97361175
94regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.96548387
95regulation of nucleobase-containing compound transport (GO:0032239)2.94885101
96negative regulation of histone modification (GO:0031057)2.93737191
97DNA alkylation (GO:0006305)2.92857892
98DNA methylation (GO:0006306)2.92857892
99regulation of mitotic metaphase/anaphase transition (GO:0030071)2.92802881
100regulation of DNA methylation (GO:0044030)2.92722355
101regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.92170680
102regulation of centrosome duplication (GO:0010824)2.91685513
103replication fork processing (GO:0031297)2.91380225
104DNA damage induced protein phosphorylation (GO:0006975)2.90502274
105DNA replication checkpoint (GO:0000076)2.89344125
106male meiosis (GO:0007140)2.89131494
107regulation of centriole replication (GO:0046599)2.89059006
108notochord development (GO:0030903)2.87979709
109peptidyl-threonine dephosphorylation (GO:0035970)2.86787085
110histone H3-K9 modification (GO:0061647)2.86044512
111histone lysine demethylation (GO:0070076)2.86007347
112mitotic spindle checkpoint (GO:0071174)2.85573330
113regulation of mitotic sister chromatid separation (GO:0010965)2.83495485
114regulation of mitotic sister chromatid segregation (GO:0033047)2.83495485
115regulation of sister chromatid segregation (GO:0033045)2.83495485
116regulation of nuclear cell cycle DNA replication (GO:0033262)2.82995998
117negative regulation of chromatin modification (GO:1903309)2.82801756
118regulation of RNA stability (GO:0043487)2.82677123
119negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.81405923
120positive regulation of DNA-dependent DNA replication (GO:2000105)2.80399195
121positive regulation of catenin import into nucleus (GO:0035413)2.80336911
122spindle assembly checkpoint (GO:0071173)2.80295586
123histone H3-K4 methylation (GO:0051568)2.79756664
124negative regulation of chromosome segregation (GO:0051985)2.79707677
125meiotic cell cycle (GO:0051321)2.79411156
126peptidyl-lysine trimethylation (GO:0018023)2.79208638
127nuclear envelope disassembly (GO:0051081)2.79049744
128membrane disassembly (GO:0030397)2.79049744
129chromatin assembly (GO:0031497)2.76854201
130histone demethylation (GO:0016577)2.76637435
131DNA conformation change (GO:0071103)2.76549661
132chromatin silencing (GO:0006342)2.75425990
133regulation of centrosome cycle (GO:0046605)2.75144982
134negative regulation of mitotic sister chromatid separation (GO:2000816)2.74982835
135negative regulation of mitotic sister chromatid segregation (GO:0033048)2.74982835
136negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.74982835
137negative regulation of sister chromatid segregation (GO:0033046)2.74982835
138regulation of mitotic spindle organization (GO:0060236)2.74659219
139mitotic spindle assembly checkpoint (GO:0007094)2.73923214
140regulation of double-strand break repair (GO:2000779)2.73513059
141regulation of pigment cell differentiation (GO:0050932)2.73409035
142DNA replication-dependent nucleosome assembly (GO:0006335)2.73152208
143DNA replication-dependent nucleosome organization (GO:0034723)2.73152208
144alternative mRNA splicing, via spliceosome (GO:0000380)2.72954790
145regulation of SMAD protein import into nucleus (GO:0060390)2.71830002
146female gamete generation (GO:0007292)2.71168885
147regulation of hippo signaling (GO:0035330)2.70292021
148N-terminal protein amino acid acetylation (GO:0006474)2.70127204
149negative regulation of gene expression, epigenetic (GO:0045814)2.69312373
150histone H3-K4 trimethylation (GO:0080182)2.67570450
151mitotic G2/M transition checkpoint (GO:0044818)2.67221459
152gastrulation with mouth forming second (GO:0001702)2.65911402
153dorsal/ventral axis specification (GO:0009950)2.65361677
154genitalia morphogenesis (GO:0035112)2.65226662
155hematopoietic stem cell differentiation (GO:0060218)2.64199706
156regulation of growth hormone secretion (GO:0060123)2.62822741
157histone H3-K9 demethylation (GO:0033169)2.62529286
158negative regulation of fibroblast apoptotic process (GO:2000270)2.62317712
159positive regulation by host of viral transcription (GO:0043923)2.60721127
160positive regulation of gene expression, epigenetic (GO:0045815)2.58067745
161negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.56780451
162positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.55906846
163determination of adult lifespan (GO:0008340)2.54653931
164negative regulation of mRNA metabolic process (GO:1903312)2.52275917
165dosage compensation (GO:0007549)2.51065889
166nodal signaling pathway (GO:0038092)2.50403416
167regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.49236111
168poly(A)+ mRNA export from nucleus (GO:0016973)2.47338799
169mitotic G2 DNA damage checkpoint (GO:0007095)2.47294670
170positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.46212567
171positive regulation of cell cycle G2/M phase transition (GO:1902751)2.46212567

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.44430173
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.71695334
3E2F4_17652178_ChIP-ChIP_JURKAT_Human4.13818566
4SALL1_21062744_ChIP-ChIP_HESCs_Human4.12080797
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.76594601
6TP63_19390658_ChIP-ChIP_HaCaT_Human3.72924835
7* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.32633975
8MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.46180207
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.44674835
10E2F1_21310950_ChIP-Seq_MCF-7_Human2.34167210
11AR_21909140_ChIP-Seq_LNCAP_Human2.31716056
12* MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.21542815
13BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.10297971
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.08497903
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.08021380
16FUS_26573619_Chip-Seq_HEK293_Human1.94522241
17ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94466845
18EGR1_19374776_ChIP-ChIP_THP-1_Human1.91756791
19CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.88401709
20MYC_18555785_ChIP-Seq_MESCs_Mouse1.84613750
21TAF15_26573619_Chip-Seq_HEK293_Human1.84404804
22MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.77001744
23HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.76654984
24SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.73452396
25AR_21572438_ChIP-Seq_LNCaP_Human1.69889521
26SCL_19346495_ChIP-Seq_HPC-7_Human1.69158406
27EWS_26573619_Chip-Seq_HEK293_Human1.66025708
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.63197523
29* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.57452156
30POU5F1_16153702_ChIP-ChIP_HESCs_Human1.53049353
31PKCTHETA_26484144_Chip-Seq_BREAST_Human1.50512585
32IGF1R_20145208_ChIP-Seq_DFB_Human1.47385415
33GATA1_22025678_ChIP-Seq_K562_Human1.43446863
34MYC_19079543_ChIP-ChIP_MESCs_Mouse1.42257781
35FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.41867451
36MYC_19030024_ChIP-ChIP_MESCs_Mouse1.39814598
37CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.37645223
38CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.37036119
39NELFA_20434984_ChIP-Seq_ESCs_Mouse1.36592592
40WT1_19549856_ChIP-ChIP_CCG9911_Human1.35347275
41PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.35222953
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34994294
43* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.34492730
44P300_19829295_ChIP-Seq_ESCs_Human1.34349861
45TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.33929870
46KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.31523817
47KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.31523817
48KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.31523817
49* SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.31009405
50FLI1_27457419_Chip-Seq_LIVER_Mouse1.27907924
51NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.27575180
52RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26324892
53TBX3_20139965_ChIP-Seq_ESCs_Mouse1.26093027
54ISL1_27105846_Chip-Seq_CPCs_Mouse1.24763811
55TBX3_20139965_ChIP-Seq_MESCs_Mouse1.24733288
56NANOG_16153702_ChIP-ChIP_HESCs_Human1.24625323
57NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.24376752
58KDM5A_27292631_Chip-Seq_BREAST_Human1.23863751
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.23098666
60PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.22730223
61FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.22411703
62PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.22357510
63IRF1_19129219_ChIP-ChIP_H3396_Human1.22154738
64TCF3_18692474_ChIP-Seq_MESCs_Mouse1.21256838
65NANOG_21062744_ChIP-ChIP_HESCs_Human1.20452453
66STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.19723617
67MYC_18940864_ChIP-ChIP_HL60_Human1.15759632
68CIITA_25753668_ChIP-Seq_RAJI_Human1.14034235
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13383241
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.12800584
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12800584
72POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.11324530
73MYC_22102868_ChIP-Seq_BL_Human1.10871498
74NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.09794035
75* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.08931247
76ER_23166858_ChIP-Seq_MCF-7_Human1.07770492
77STAT3_23295773_ChIP-Seq_U87_Human1.07477702
78RNF2_27304074_Chip-Seq_NSC_Mouse1.06864763
79SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.06787592
80SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.05122852
81PADI4_21655091_ChIP-ChIP_MCF-7_Human1.03714754
82NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.01875327
83NANOG_18555785_ChIP-Seq_MESCs_Mouse1.01866865
84STAT6_21828071_ChIP-Seq_BEAS2B_Human1.01855792
85RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.01403946
86PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.01352617
87ELK1_19687146_ChIP-ChIP_HELA_Human1.00141557
88GATA1_26923725_Chip-Seq_HPCs_Mouse0.99973075
89PIAS1_25552417_ChIP-Seq_VCAP_Human0.97579544
90CHD1_26751641_Chip-Seq_LNCaP_Human0.96834758
91* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.96631271
92STAT3_18555785_ChIP-Seq_MESCs_Mouse0.96320824
93* TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.94783649
94PCGF2_27294783_Chip-Seq_ESCs_Mouse0.94522975
95VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.94390214
96GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93181208
97VDR_23849224_ChIP-Seq_CD4+_Human0.92258343
98E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.91517278
99EZH2_22144423_ChIP-Seq_EOC_Human0.91137426
100TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.90680360
101ZNF217_24962896_ChIP-Seq_MCF-7_Human0.90306622
102KAP1_22055183_ChIP-Seq_ESCs_Mouse0.90070704
103FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89581271
104EST1_17652178_ChIP-ChIP_JURKAT_Human0.89245682
105SOX2_16153702_ChIP-ChIP_HESCs_Human0.88953753
106CTNNB1_20460455_ChIP-Seq_HCT116_Human0.88850011
107YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88577364
108* TCF4_23295773_ChIP-Seq_U87_Human0.87974474
109SALL4_18804426_ChIP-ChIP_XEN_Mouse0.86439308
110CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.85221635
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85044582
112TCF7_22412390_ChIP-Seq_EML_Mouse0.84914007
113GF1B_26923725_Chip-Seq_HPCs_Mouse0.84880748
114HOXB4_20404135_ChIP-ChIP_EML_Mouse0.84435759
115UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84308590
116STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.83171020
117ZNF274_21170338_ChIP-Seq_K562_Hela0.83031543
118TCF3_18692474_ChIP-Seq_MEFs_Mouse0.82819546
119ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.81749230
120TOP2B_26459242_ChIP-Seq_MCF-7_Human0.81579146
121TTF2_22483619_ChIP-Seq_HELA_Human0.81117249
122AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.80315550
123XRN2_22483619_ChIP-Seq_HELA_Human0.79746627
124CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.78172691
125CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78042866
126MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.77527981
127SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.77407753
128FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.76903010
129TBL1_22424771_ChIP-Seq_293T_Human0.76572410
130TCF4_18268006_ChIP-ChIP_LS174T_Human0.76197028
131HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.74402822
132POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.74371339
133NANOG_18555785_Chip-Seq_ESCs_Mouse0.73842183
134TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.73604844
135NOTCH1_21737748_ChIP-Seq_TLL_Human0.73174626
136KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.73116395
137CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.72625912
138ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.72611998
139TP53_16413492_ChIP-PET_HCT116_Human0.72562590
140RUNX1_26923725_Chip-Seq_HPCs_Mouse0.72450247
141* FOXP3_21729870_ChIP-Seq_TREG_Human0.72271016

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication3.95514901
2MP0010094_abnormal_chromosome_stability3.37905066
3MP0008877_abnormal_DNA_methylation3.28277911
4MP0003693_abnormal_embryo_hatching3.19155849
5MP0003077_abnormal_cell_cycle3.08594380
6MP0003111_abnormal_nucleus_morphology3.05636910
7MP0003787_abnormal_imprinting2.65097297
8MP0004957_abnormal_blastocyst_morpholog2.59746971
9MP0008007_abnormal_cellular_replicative2.54285778
10MP0003121_genomic_imprinting2.42073097
11MP0006292_abnormal_olfactory_placode2.39004973
12MP0008058_abnormal_DNA_repair2.24687607
13MP0003890_abnormal_embryonic-extraembry2.24179309
14MP0003937_abnormal_limbs/digits/tail_de2.18474207
15MP0000566_synostosis1.95985184
16MP0003123_paternal_imprinting1.90824300
17MP0000350_abnormal_cell_proliferation1.90198986
18MP0003122_maternal_imprinting1.88497885
19MP0002084_abnormal_developmental_patter1.80763119
20MP0001730_embryonic_growth_arrest1.80697751
21MP0002396_abnormal_hematopoietic_system1.76957173
22MP0002085_abnormal_embryonic_tissue1.75613628
23MP0008932_abnormal_embryonic_tissue1.70211262
24MP0005451_abnormal_body_composition1.70051573
25MP0001672_abnormal_embryogenesis/_devel1.68487688
26MP0005380_embryogenesis_phenotype1.68487688
27MP0002102_abnormal_ear_morphology1.64936632
28MP0002210_abnormal_sex_determination1.64426286
29MP0010030_abnormal_orbit_morphology1.63259225
30MP0001188_hyperpigmentation1.62904202
31MP0003718_maternal_effect1.59838190
32MP0002653_abnormal_ependyma_morphology1.59343444
33MP0001697_abnormal_embryo_size1.59278409
34MP0000537_abnormal_urethra_morphology1.59138857
35MP0003567_abnormal_fetal_cardiomyocyte1.55947249
36MP0010307_abnormal_tumor_latency1.52712576
37MP0001929_abnormal_gametogenesis1.46570543
38MP0001293_anophthalmia1.46256585
39MP0002249_abnormal_larynx_morphology1.45186326
40MP0003984_embryonic_growth_retardation1.44635543
41MP0002254_reproductive_system_inflammat1.43697134
42MP0005076_abnormal_cell_differentiation1.43162326
43MP0002088_abnormal_embryonic_growth/wei1.41255527
44MP0003183_abnormal_peptide_metabolism1.38367775
45MP0000383_abnormal_hair_follicle1.35379000
46MP0002938_white_spotting1.35280619
47MP0003755_abnormal_palate_morphology1.33248237
48MP0000653_abnormal_sex_gland1.32696912
49MP0001145_abnormal_male_reproductive1.31958753
50MP0002086_abnormal_extraembryonic_tissu1.31067527
51MP0009697_abnormal_copulation1.30853748
52MP0003315_abnormal_perineum_morphology1.28693938
53MP0003935_abnormal_craniofacial_develop1.28242610
54MP0000432_abnormal_head_morphology1.24494185
55MP0004264_abnormal_extraembryonic_tissu1.23723758
56MP0010678_abnormal_skin_adnexa1.23495254
57MP0001119_abnormal_female_reproductive1.22655186
58MP0001286_abnormal_eye_development1.20433860
59MP0005248_abnormal_Harderian_gland1.19742660
60MP0003385_abnormal_body_wall1.19085014
61MP0009053_abnormal_anal_canal1.18341577
62MP0004808_abnormal_hematopoietic_stem1.15935197
63MP0004197_abnormal_fetal_growth/weight/1.15545581
64MP0004185_abnormal_adipocyte_glucose1.15270375
65MP0009250_abnormal_appendicular_skeleto1.15221367
66MP0000569_abnormal_digit_pigmentation1.14123459
67MP0002233_abnormal_nose_morphology1.12129726
68MP0003943_abnormal_hepatobiliary_system1.11740079
69MP0003861_abnormal_nervous_system1.11696702
70MP0003115_abnormal_respiratory_system1.07962240
71MP0002080_prenatal_lethality1.07459910
72MP0003938_abnormal_ear_development1.07103764
73MP0003942_abnormal_urinary_system1.06010050
74MP0009703_decreased_birth_body1.04328863
75MP0005408_hypopigmentation1.02969658
76MP0003941_abnormal_skin_development1.02248238
77MP0005220_abnormal_exocrine_pancreas1.01700245
78MP0009672_abnormal_birth_weight1.01578149
79MP0000490_abnormal_crypts_of1.00655329
80MP0001915_intracranial_hemorrhage1.00315547
81MP0002009_preneoplasia1.00260633
82MP0000428_abnormal_craniofacial_morphol0.96811610
83MP0003119_abnormal_digestive_system0.96254521
84MP0002111_abnormal_tail_morphology0.95830893
85MP0001849_ear_inflammation0.94515742
86MP0008961_abnormal_basal_metabolism0.94454439
87MP0003699_abnormal_female_reproductive0.93871685
88MP0003698_abnormal_male_reproductive0.93751064
89MP0001545_abnormal_hematopoietic_system0.93604300
90MP0005397_hematopoietic_system_phenotyp0.93604300
91MP0002116_abnormal_craniofacial_bone0.93546500
92MP0003878_abnormal_ear_physiology0.93094400
93MP0005377_hearing/vestibular/ear_phenot0.93094400
94MP0001346_abnormal_lacrimal_gland0.92582402
95MP0002092_abnormal_eye_morphology0.90919623
96MP0005666_abnormal_adipose_tissue0.89469776
97MP0010352_gastrointestinal_tract_polyps0.88647232
98MP0009278_abnormal_bone_marrow0.87809717
99MP0000703_abnormal_thymus_morphology0.87732156
100MP0005187_abnormal_penis_morphology0.87085083
101MP0005367_renal/urinary_system_phenotyp0.86988150
102MP0000516_abnormal_urinary_system0.86988150
103MP0004381_abnormal_hair_follicle0.85774224
104MP0005409_darkened_coat_color0.85489604
105MP0003936_abnormal_reproductive_system0.83972955
106MP0000313_abnormal_cell_death0.83718269
107MP0000049_abnormal_middle_ear0.83044397
108MP0002932_abnormal_joint_morphology0.82856690
109MP0002081_perinatal_lethality0.82732058
110MP0000733_abnormal_muscle_development0.81645294
111MP0002019_abnormal_tumor_incidence0.81286574
112MP0002697_abnormal_eye_size0.80693614
113MP0002114_abnormal_axial_skeleton0.80675980
114MP0003763_abnormal_thymus_physiology0.80193562
115MP0002925_abnormal_cardiovascular_devel0.80159451
116MP0003786_premature_aging0.79666975
117MP0002160_abnormal_reproductive_system0.79095286
118MP0010630_abnormal_cardiac_muscle0.78306275
119MP0005075_abnormal_melanosome_morpholog0.78146755
120MP0003136_yellow_coat_color0.77984566
121MP0000631_abnormal_neuroendocrine_gland0.77720231
122MP0008789_abnormal_olfactory_epithelium0.76801478
123MP0002751_abnormal_autonomic_nervous0.74371441
124MP0008770_decreased_survivor_rate0.73758012
125MP0005464_abnormal_platelet_physiology0.71977188
126MP0000778_abnormal_nervous_system0.71258572
127MP0002166_altered_tumor_susceptibility0.69502163
128MP0000534_abnormal_ureter_morphology0.69466994
129MP0001340_abnormal_eyelid_morphology0.69189170
130MP0005174_abnormal_tail_pigmentation0.64274675
131MP0003221_abnormal_cardiomyocyte_apopto0.63396933
132MP0004133_heterotaxia0.62488679

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.47604799
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.19351906
3Volvulus (HP:0002580)3.81402238
4Hepatoblastoma (HP:0002884)3.64716577
5Abnormality of the fingertips (HP:0001211)3.58352285
6Papillary thyroid carcinoma (HP:0002895)3.49519816
7Ectopic kidney (HP:0000086)3.39080900
8Facial hemangioma (HP:0000329)3.33606943
9Abnormality of the labia minora (HP:0012880)3.15495268
10Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.99205819
11Short 4th metacarpal (HP:0010044)2.99205819
12Abnormality of chromosome stability (HP:0003220)2.95806263
13Birth length less than 3rd percentile (HP:0003561)2.80705800
14Acute myeloid leukemia (HP:0004808)2.79301294
15Patellar aplasia (HP:0006443)2.77916859
16Meckel diverticulum (HP:0002245)2.71588300
17Biliary tract neoplasm (HP:0100574)2.71273758
18Malignant gastrointestinal tract tumors (HP:0006749)2.70049040
19Gastrointestinal carcinoma (HP:0002672)2.70049040
20Lip pit (HP:0100267)2.68134944
21Shawl scrotum (HP:0000049)2.68066581
22Aplasia/Hypoplasia of the uvula (HP:0010293)2.64279003
23Diastasis recti (HP:0001540)2.64211076
24Oligodactyly (HP:0012165)2.62189457
25Capillary hemangiomas (HP:0005306)2.59780378
26Aplasia/Hypoplasia of the patella (HP:0006498)2.58253124
27Neoplasm of the oral cavity (HP:0100649)2.57761237
28Acanthocytosis (HP:0001927)2.57098802
29Abnormality of the ileum (HP:0001549)2.55660428
30Medulloblastoma (HP:0002885)2.54919760
31Neoplasm of the adrenal cortex (HP:0100641)2.50043035
32Midline defect of the nose (HP:0004122)2.48808049
33Prostate neoplasm (HP:0100787)2.46170053
34Supernumerary spleens (HP:0009799)2.45121960
35Abnormality of the preputium (HP:0100587)2.44350935
36Oligodactyly (hands) (HP:0001180)2.42716879
37Myelodysplasia (HP:0002863)2.41463997
38Long eyelashes (HP:0000527)2.37229168
39Abnormality of the phalanges of the hallux (HP:0010057)2.36560704
40Nephroblastoma (Wilms tumor) (HP:0002667)2.32298459
41Aplasia/Hypoplasia of the sternum (HP:0006714)2.26269571
42Transitional cell carcinoma of the bladder (HP:0006740)2.24588404
43Neoplasm of the small intestine (HP:0100833)2.24241281
44Small intestinal stenosis (HP:0012848)2.24101550
45Duodenal stenosis (HP:0100867)2.24101550
46Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.23578790
47Short thumb (HP:0009778)2.21663372
48Abnormal lung lobation (HP:0002101)2.19802207
49Impulsivity (HP:0100710)2.19191453
50Absent radius (HP:0003974)2.17072029
51Supernumerary bones of the axial skeleton (HP:0009144)2.16850080
52High anterior hairline (HP:0009890)2.14536280
53Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.14224272
54Embryonal renal neoplasm (HP:0011794)2.13565897
55Sparse lateral eyebrow (HP:0005338)2.13272210
56Abnormality of the 4th metacarpal (HP:0010012)2.12604619
57Embryonal neoplasm (HP:0002898)2.12460510
58Septo-optic dysplasia (HP:0100842)2.12254692
59Aqueductal stenosis (HP:0002410)2.12030726
60Neonatal hypoglycemia (HP:0001998)2.11077389
61Abnormality of the parietal bone (HP:0002696)2.10822429
62Curly hair (HP:0002212)2.10803945
63Chin dimple (HP:0010751)2.08986452
64Adrenal hypoplasia (HP:0000835)2.08649451
65Colon cancer (HP:0003003)2.07458958
66Trigonocephaly (HP:0000243)2.07318914
67Bladder carcinoma (HP:0002862)2.06326290
68Bladder neoplasm (HP:0009725)2.06326290
69Absent forearm bone (HP:0003953)2.05905017
70Aplasia involving forearm bones (HP:0009822)2.05905017
71Abnormal hair whorl (HP:0010721)2.05732474
72Abnormality of the carotid arteries (HP:0005344)2.05610214
73Supernumerary ribs (HP:0005815)2.04598465
74Rib fusion (HP:0000902)2.03597137
75Abnormality of chromosome segregation (HP:0002916)2.02452374
76Obsessive-compulsive behavior (HP:0000722)2.01906612
77Asymmetry of the thorax (HP:0001555)2.01120128
78Abnormality of the pubic bones (HP:0003172)2.01097842
79Leiomyosarcoma (HP:0100243)1.99352050
80Uterine leiomyosarcoma (HP:0002891)1.99352050
81Truncal obesity (HP:0001956)1.99247187
82Breast hypoplasia (HP:0003187)1.98723234
83Abnormality of the duodenum (HP:0002246)1.98441259
84Increased nuchal translucency (HP:0010880)1.93801766
85Absent eyebrow (HP:0002223)1.92334467
86Overlapping toe (HP:0001845)1.92033063
87Prolonged bleeding time (HP:0003010)1.91117820
88Intestinal fistula (HP:0100819)1.90495256
89Thyroid carcinoma (HP:0002890)1.90390947
90Acute lymphatic leukemia (HP:0006721)1.89329524
91Esophageal atresia (HP:0002032)1.89217278
92Sloping forehead (HP:0000340)1.89166917
93Male infertility (HP:0003251)1.88938434
94Microtia (HP:0008551)1.87769766
95Cystic hygroma (HP:0000476)1.87750562
962-3 toe syndactyly (HP:0004691)1.87408598
97Clubbing of toes (HP:0100760)1.85043433
98Sandal gap (HP:0001852)1.84566302
99Broad palm (HP:0001169)1.84536206
100Atresia of the external auditory canal (HP:0000413)1.83111385
101Broad thumb (HP:0011304)1.82705700
102Anal stenosis (HP:0002025)1.82507235
103Prominent nose (HP:0000448)1.81674182
104Hypochromic microcytic anemia (HP:0004840)1.80574373
105Microglossia (HP:0000171)1.80498696
106Rectal fistula (HP:0100590)1.79338486
107Rectovaginal fistula (HP:0000143)1.79338486
108Rhabdomyosarcoma (HP:0002859)1.79061539
109Cutaneous syndactyly (HP:0012725)1.78877073
110Protruding tongue (HP:0010808)1.78313571
111Breast aplasia (HP:0100783)1.77840211
112Cupped ear (HP:0000378)1.77678137
113Hemivertebrae (HP:0002937)1.76504155
114Abnormality of the columella (HP:0009929)1.75468461
115Vertebral arch anomaly (HP:0008438)1.74584507
116Short middle phalanx of the 5th finger (HP:0004220)1.74529373
117Uterine neoplasm (HP:0010784)1.74367158
118Proximal placement of thumb (HP:0009623)1.73746692
119Hypotelorism (HP:0000601)1.73299025
120Abnormality of the distal phalanx of the thumb (HP:0009617)1.72857186
121Aplasia/Hypoplasia of the earlobes (HP:0009906)1.72409806
122Ependymoma (HP:0002888)1.71308826
123Abnormality of lateral ventricle (HP:0030047)1.71032760
124Triphalangeal thumb (HP:0001199)1.69680279
125Low anterior hairline (HP:0000294)1.68327305
126Aplasia/Hypoplasia of the breasts (HP:0010311)1.67816254
127Omphalocele (HP:0001539)1.67432812
128Renal hypoplasia (HP:0000089)1.66786630
129Enlarged kidneys (HP:0000105)1.66719576
130Preaxial foot polydactyly (HP:0001841)1.66260404
131Deviation of the thumb (HP:0009603)1.65902240
132Broad alveolar ridges (HP:0000187)1.65712482
133Deep philtrum (HP:0002002)1.64754752
134Hypoplastic labia majora (HP:0000059)1.64082907
135Neoplasm of striated muscle (HP:0009728)1.63953755
136Neoplasm of the colon (HP:0100273)1.63895707
137Heterotopia (HP:0002282)1.62779056
138Cafe-au-lait spot (HP:0000957)1.61899259
139Depressed nasal tip (HP:0000437)1.61724976
140Abnormality of the left ventricular outflow tract (HP:0011103)1.61286205
141Subaortic stenosis (HP:0001682)1.61286205
142Cutaneous finger syndactyly (HP:0010554)1.60219198
143Germ cell neoplasia (HP:0100728)1.60066273
144Urethral obstruction (HP:0000796)1.59473280
145Cutis marmorata (HP:0000965)1.59432399
146Abnormality of the incisor (HP:0000676)1.59414641
147Duplicated collecting system (HP:0000081)1.59391782
148Blepharitis (HP:0000498)1.59345083
149Gastrointestinal atresia (HP:0002589)1.59005466
150Choanal stenosis (HP:0000452)1.58985199
151Cortical dysplasia (HP:0002539)1.57842821
152Abnormality of the intervertebral disk (HP:0005108)1.56633425
153Short middle phalanx of finger (HP:0005819)1.56109907
154Abnormality of the nasal septum (HP:0000419)1.55573523
155Abnormal biliary tract morphology (HP:0012440)1.55358538
156Skull defect (HP:0001362)1.55280518

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS16.25589451
2CDC74.65285739
3STK38L3.96776696
4LATS23.82167560
5MAP3K103.70176680
6CDK123.27744823
7STK32.60173170
8SRPK12.48107983
9NEK22.45891813
10PLK42.23725110
11MKNK12.21673867
12TTK2.21433840
13MKNK22.18549214
14MAP3K62.04162868
15TAF12.03870832
16TNIK2.03391777
17CHEK21.90913883
18WEE11.87202970
19ZAK1.61205360
20BRD41.58810003
21MELK1.55087046
22PLK11.42396043
23ERBB41.42284541
24CDK71.41996560
25CHEK11.38976653
26CDK191.38435525
27CDK91.34783245
28ATM1.33216544
29CDK81.32537641
30ATR1.30965984
31FGFR11.29078913
32TEC1.26674217
33DYRK31.25381837
34DYRK21.22850996
35AURKB1.22065635
36CDK41.20670830
37TAOK31.15305321
38SGK21.14447900
39PLK31.14361236
40CSNK1G11.14002627
41CDK61.11908809
42ACVR1B1.10147059
43BUB11.09086781
44BRSK21.07143127
45CDK31.05721320
46NUAK11.03512754
47FGFR41.01616962
48EEF2K0.99820808
49CSNK1A1L0.98732779
50CASK0.96791968
51PNCK0.95629035
52STK380.91009870
53CAMK1D0.90809890
54CDK20.89707846
55FRK0.88025342
56PDGFRB0.86695932
57CAMK1G0.85405058
58BTK0.84067051
59STK390.83805471
60STK40.81596766
61CDK10.81175754
62AKT30.80133707
63CSNK1G30.79641886
64RPS6KB20.78713165
65MAPK130.77925290
66STK100.77834755
67VRK10.76026475
68NLK0.75089873
69PRKD30.73834768
70MAP3K80.72034431
71SGK30.70564173
72SGK2230.69431819
73SGK4940.69431819
74TAOK10.69014450
75BMX0.67879272
76MARK20.66543194
77WNK30.66429789
78DYRK1B0.66283138
79CSNK1D0.64224725
80SMG10.63926631
81CSNK1G20.62467114
82PIM10.61289621
83ABL20.59730621
84RPS6KB10.59145315
85TSSK60.58767764
86MTOR0.58680139
87PKN20.57404354
88MAP3K70.57333015
89STK110.56068309
90MAPK100.55872219
91TYRO30.55836490
92JAK30.55256453
93MAPK140.54595375
94ABL10.52616178
95RET0.52558587
96CHUK0.50893572
97STK240.50546521
98WNK40.49969490
99RPS6KA40.48356183
100FGR0.47371546
101DMPK0.45226752
102GSK3B0.44950060
103INSRR0.44219558
104PIK3CA0.44111994
105RAF10.43977377
106AKT10.42798183
107RPS6KA50.41951562
108ALK0.41366143
109CSNK1E0.41350572
110YES10.40803188
111PRKDC0.40513657
112DYRK1A0.40009577
113KSR10.39537086
114TGFBR10.38651904
115MAPK10.38255744
116ITK0.38166065
117BMPR1B0.38109043
118AURKA0.37721578
119PASK0.36622044
120HIPK20.36461831
121MAP3K50.36410125
122FGFR20.36332667
123PRKD20.36100652
124CLK10.35476625
125MAP2K20.34243998
126BMPR20.33182833
127ICK0.33174058
128SGK10.33091994
129MAP3K40.33018750
130MATK0.32788121
131WNK10.31748427
132EIF2AK20.29022266
133FGFR30.24973397
134PRKAA20.24840820
135MUSK0.24308171
136BCR0.22557278

Predicted pathways (KEGG)

RankGene SetZ-score
1Cell cycle_Homo sapiens_hsa041103.31301023
2Basal transcription factors_Homo sapiens_hsa030222.88752913
3Fanconi anemia pathway_Homo sapiens_hsa034602.85998473
4Homologous recombination_Homo sapiens_hsa034402.62828808
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.59089500
6RNA degradation_Homo sapiens_hsa030182.56847528
7RNA transport_Homo sapiens_hsa030132.54645321
8Spliceosome_Homo sapiens_hsa030402.45037048
9Mismatch repair_Homo sapiens_hsa034302.43078499
10DNA replication_Homo sapiens_hsa030302.40805304
11Non-homologous end-joining_Homo sapiens_hsa034502.40557631
12mRNA surveillance pathway_Homo sapiens_hsa030152.21588071
13RNA polymerase_Homo sapiens_hsa030202.19099428
14p53 signaling pathway_Homo sapiens_hsa041151.91578567
15Base excision repair_Homo sapiens_hsa034101.87803380
16MicroRNAs in cancer_Homo sapiens_hsa052061.80546590
17TGF-beta signaling pathway_Homo sapiens_hsa043501.71027576
18Nucleotide excision repair_Homo sapiens_hsa034201.68723499
19Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.65091937
20Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.58927123
21Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.57052820
22Basal cell carcinoma_Homo sapiens_hsa052171.52125163
23Herpes simplex infection_Homo sapiens_hsa051681.48029220
24Platelet activation_Homo sapiens_hsa046111.45396389
25Oocyte meiosis_Homo sapiens_hsa041141.35468992
26Transcriptional misregulation in cancer_Homo sapiens_hsa052021.34633992
27Colorectal cancer_Homo sapiens_hsa052101.29632756
28Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.28462185
29Dorso-ventral axis formation_Homo sapiens_hsa043201.24641283
30Hippo signaling pathway_Homo sapiens_hsa043901.21241869
31One carbon pool by folate_Homo sapiens_hsa006701.21051427
32Small cell lung cancer_Homo sapiens_hsa052221.20203668
33Hedgehog signaling pathway_Homo sapiens_hsa043401.19700835
34Notch signaling pathway_Homo sapiens_hsa043301.17995872
35Lysine degradation_Homo sapiens_hsa003101.17234014
36Prostate cancer_Homo sapiens_hsa052151.16078549
37Phosphatidylinositol signaling system_Homo sapiens_hsa040701.14681679
38Pyrimidine metabolism_Homo sapiens_hsa002401.14600728
39Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.14595924
40Selenocompound metabolism_Homo sapiens_hsa004501.14522847
41Pancreatic cancer_Homo sapiens_hsa052121.14005118
42Long-term depression_Homo sapiens_hsa047301.12866042
43Wnt signaling pathway_Homo sapiens_hsa043101.11455416
44Adherens junction_Homo sapiens_hsa045201.09783353
45Inositol phosphate metabolism_Homo sapiens_hsa005621.06021220
46Thyroid cancer_Homo sapiens_hsa052161.00019123
47HTLV-I infection_Homo sapiens_hsa051660.98535229
48Chronic myeloid leukemia_Homo sapiens_hsa052200.97834520
49Epstein-Barr virus infection_Homo sapiens_hsa051690.95053400
50Viral carcinogenesis_Homo sapiens_hsa052030.95017159
51Pathways in cancer_Homo sapiens_hsa052000.86447517
52VEGF signaling pathway_Homo sapiens_hsa043700.86421085
53Phospholipase D signaling pathway_Homo sapiens_hsa040720.84871438
54Endometrial cancer_Homo sapiens_hsa052130.83926959
55Renal cell carcinoma_Homo sapiens_hsa052110.83665383
56NF-kappa B signaling pathway_Homo sapiens_hsa040640.82432974
57Ether lipid metabolism_Homo sapiens_hsa005650.81763498
58Non-small cell lung cancer_Homo sapiens_hsa052230.80396046
59Hepatitis B_Homo sapiens_hsa051610.79842451
60FoxO signaling pathway_Homo sapiens_hsa040680.79259554
61NOD-like receptor signaling pathway_Homo sapiens_hsa046210.77964564
62Prolactin signaling pathway_Homo sapiens_hsa049170.77507587
63Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.76920008
64Insulin signaling pathway_Homo sapiens_hsa049100.76806152
65Ovarian steroidogenesis_Homo sapiens_hsa049130.75745723
66Linoleic acid metabolism_Homo sapiens_hsa005910.73367296
67Viral myocarditis_Homo sapiens_hsa054160.72711280
68Cysteine and methionine metabolism_Homo sapiens_hsa002700.72563404
69Choline metabolism in cancer_Homo sapiens_hsa052310.71625363
70Circadian rhythm_Homo sapiens_hsa047100.71475875
71Gap junction_Homo sapiens_hsa045400.69950800
72mTOR signaling pathway_Homo sapiens_hsa041500.69015561
73Vitamin digestion and absorption_Homo sapiens_hsa049770.68763175
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68146172
75Purine metabolism_Homo sapiens_hsa002300.68011190
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.67666166
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.66220619
78Systemic lupus erythematosus_Homo sapiens_hsa053220.65375004
79Long-term potentiation_Homo sapiens_hsa047200.63237412
80AMPK signaling pathway_Homo sapiens_hsa041520.62270785
81Fatty acid biosynthesis_Homo sapiens_hsa000610.62208720
82Taste transduction_Homo sapiens_hsa047420.62066442
83ErbB signaling pathway_Homo sapiens_hsa040120.61598298
84Melanoma_Homo sapiens_hsa052180.59790802
85Influenza A_Homo sapiens_hsa051640.59063654
86Vitamin B6 metabolism_Homo sapiens_hsa007500.58503302
87Measles_Homo sapiens_hsa051620.58139404
88Rap1 signaling pathway_Homo sapiens_hsa040150.57243470
89Central carbon metabolism in cancer_Homo sapiens_hsa052300.56964990
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.56583019
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56399852
92Type II diabetes mellitus_Homo sapiens_hsa049300.55760693
93Leukocyte transendothelial migration_Homo sapiens_hsa046700.55515248
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.53781154
95Tight junction_Homo sapiens_hsa045300.53498670
96Estrogen signaling pathway_Homo sapiens_hsa049150.53118936
97Serotonergic synapse_Homo sapiens_hsa047260.52406534
98Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.51103311
99Cholinergic synapse_Homo sapiens_hsa047250.50441496
100MAPK signaling pathway_Homo sapiens_hsa040100.49767259
101Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.48551716
102Insulin resistance_Homo sapiens_hsa049310.47802353
103Ras signaling pathway_Homo sapiens_hsa040140.47684104
104Axon guidance_Homo sapiens_hsa043600.47512086
105T cell receptor signaling pathway_Homo sapiens_hsa046600.46794152
106Toxoplasmosis_Homo sapiens_hsa051450.46697814
107Phototransduction_Homo sapiens_hsa047440.46359323
108Glucagon signaling pathway_Homo sapiens_hsa049220.46235381
109Acute myeloid leukemia_Homo sapiens_hsa052210.45905762
110cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45785656
111Proteoglycans in cancer_Homo sapiens_hsa052050.45527228
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45473184
113B cell receptor signaling pathway_Homo sapiens_hsa046620.42970528
114TNF signaling pathway_Homo sapiens_hsa046680.42934099
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41421262
116Longevity regulating pathway - mammal_Homo sapiens_hsa042110.41103312
117Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.40766446
118Shigellosis_Homo sapiens_hsa051310.40565516
119PI3K-Akt signaling pathway_Homo sapiens_hsa041510.40168821
120Primary immunodeficiency_Homo sapiens_hsa053400.38735499
121Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37692022
122Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.36287788
123Antigen processing and presentation_Homo sapiens_hsa046120.32669060
124Chemokine signaling pathway_Homo sapiens_hsa040620.32413789
125Hematopoietic cell lineage_Homo sapiens_hsa046400.30643599
126Intestinal immune network for IgA production_Homo sapiens_hsa046720.30486028
127Glioma_Homo sapiens_hsa052140.30291173
128Alcoholism_Homo sapiens_hsa050340.29923967
129AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.29439728
130Apoptosis_Homo sapiens_hsa042100.28894706
131Melanogenesis_Homo sapiens_hsa049160.27751734
132Sphingolipid signaling pathway_Homo sapiens_hsa040710.27277686

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