MCAM

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1endothelium development (GO:0003158)7.27874289
2central nervous system myelination (GO:0022010)5.71370823
3axon ensheathment in central nervous system (GO:0032291)5.71370823
4retina vasculature morphogenesis in camera-type eye (GO:0061299)5.21312642
5ensheathment of neurons (GO:0007272)5.18151993
6axon ensheathment (GO:0008366)5.18151993
7myelination (GO:0042552)5.06053879
8peptidyl-tyrosine autophosphorylation (GO:0038083)4.63746610
9wound healing, spreading of epidermal cells (GO:0035313)4.51313305
10adhesion of symbiont to host cell (GO:0044650)4.37325467
11virion attachment to host cell (GO:0019062)4.37325467
12negative regulation of blood vessel endothelial cell migration (GO:0043537)4.22800553
13protein localization to endosome (GO:0036010)4.07281516
14peripheral nervous system axon ensheathment (GO:0032292)4.03028833
15myelination in peripheral nervous system (GO:0022011)4.03028833
16low-density lipoprotein particle clearance (GO:0034383)4.02364787
17morphogenesis of an endothelium (GO:0003159)3.94243593
18endothelial tube morphogenesis (GO:0061154)3.94243593
19sprouting angiogenesis (GO:0002040)3.91464240
20endodermal cell differentiation (GO:0035987)3.87921426
21regulation of cell migration involved in sprouting angiogenesis (GO:0090049)3.78419984
22myelin maintenance (GO:0043217)3.76234963
23astrocyte development (GO:0014002)3.75675692
24adhesion of symbiont to host (GO:0044406)3.74710630
25vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.74089226
26fatty acid elongation (GO:0030497)3.70333913
27cell-substrate junction assembly (GO:0007044)3.67659217
28regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.63069110
29Notch signaling involved in heart development (GO:0061314)3.61420319
30negative regulation of focal adhesion assembly (GO:0051895)3.58950975
31negative regulation of cell junction assembly (GO:1901889)3.58950975
32negative regulation of adherens junction organization (GO:1903392)3.58950975
33creatine metabolic process (GO:0006600)3.50806834
34negative regulation of endothelial cell migration (GO:0010596)3.50621731
35endothelial cell morphogenesis (GO:0001886)3.44837424
36regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.44091954
37basement membrane organization (GO:0071711)3.37930451
38cytoskeletal anchoring at plasma membrane (GO:0007016)3.35749724
39cellular response to epinephrine stimulus (GO:0071872)3.35422995
40cell migration involved in heart development (GO:0060973)3.32587081
41positive regulation of endothelial cell apoptotic process (GO:2000353)3.31747213
42endothelial cell differentiation (GO:0045446)3.29082432
43vascular endothelial growth factor signaling pathway (GO:0038084)3.28231633
44asymmetric protein localization (GO:0008105)3.26465859
45patterning of blood vessels (GO:0001569)3.25812377
46chondrocyte proliferation (GO:0035988)3.23497822
47L-serine transport (GO:0015825)3.19886291
48negative regulation of neurotransmitter secretion (GO:0046929)3.19438541
49long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.19116915
50apical protein localization (GO:0045176)3.18928245
51positive regulation of odontogenesis (GO:0042482)3.18907214
52wound healing, spreading of cells (GO:0044319)3.18553606
53regulation of blood vessel endothelial cell migration (GO:0043535)3.17737516
54substrate-dependent cell migration (GO:0006929)3.17001279
55ovulation from ovarian follicle (GO:0001542)3.15651139
56negative regulation of chondrocyte differentiation (GO:0032331)3.15415724
57regulation of endothelial cell differentiation (GO:0045601)3.15151540
58membrane raft organization (GO:0031579)3.14407296
59protein heterotrimerization (GO:0070208)3.13677284
60negative regulation of cartilage development (GO:0061037)3.09612623
61positive regulation of urine volume (GO:0035810)3.07696117
62adherens junction assembly (GO:0034333)3.07606901
63import into cell (GO:0098657)3.07117551
64enteric nervous system development (GO:0048484)3.06240446
65negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)3.04747552
66negative regulation of protein localization to cell surface (GO:2000009)3.00443691
67positive regulation of endothelial cell differentiation (GO:0045603)2.99171003
68membrane assembly (GO:0071709)2.98944741
69blood vessel maturation (GO:0001955)2.98747904
70fatty-acyl-CoA biosynthetic process (GO:0046949)2.97656738
71substrate adhesion-dependent cell spreading (GO:0034446)2.96823978
72positive regulation of receptor recycling (GO:0001921)2.96220652
73long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.95388814
74positive regulation of glomerulus development (GO:0090193)2.95229611
75neuron remodeling (GO:0016322)2.94960066
76nephron epithelium development (GO:0072009)2.92801373
77endothelial cell proliferation (GO:0001935)2.92693391
78artery development (GO:0060840)2.89006014
79negative regulation of fatty acid transport (GO:2000192)2.89004325
80regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.87616700
81apoptotic cell clearance (GO:0043277)2.85197376
82negative regulation of endothelial cell proliferation (GO:0001937)2.84943599
83cell-substrate adherens junction assembly (GO:0007045)2.84388865
84focal adhesion assembly (GO:0048041)2.84388865
85neuron projection extension involved in neuron projection guidance (GO:1902284)2.83238121
86axon extension involved in axon guidance (GO:0048846)2.83238121
87oligodendrocyte differentiation (GO:0048709)2.83003009
88negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.82792625
89response to lipoprotein particle (GO:0055094)2.81228038
90negative regulation of Rho protein signal transduction (GO:0035024)2.80458683
91atrioventricular valve morphogenesis (GO:0003181)2.79449485
92positive regulation of endothelial cell migration (GO:0010595)2.79443590
93interleukin-6-mediated signaling pathway (GO:0070102)2.79395216
94negative regulation of DNA biosynthetic process (GO:2000279)2.77757128
95regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947)2.77140923
96triglyceride catabolic process (GO:0019433)2.76963533
97hemidesmosome assembly (GO:0031581)2.76721447
98regulation of endothelial cell migration (GO:0010594)2.76079074
99positive regulation of blood vessel endothelial cell migration (GO:0043536)2.75750177
100glomerular basement membrane development (GO:0032836)2.75521444
101barbed-end actin filament capping (GO:0051016)2.74725581
102endocardial cushion development (GO:0003197)2.74630837
103extracellular fibril organization (GO:0043206)2.74381206
104lymphangiogenesis (GO:0001946)2.72890814
105fatty-acyl-CoA metabolic process (GO:0035337)2.71688988
106vasculogenesis (GO:0001570)2.71656240
107regulation of cardioblast differentiation (GO:0051890)2.71318063
108endothelial cell chemotaxis (GO:0035767)2.70917493
109response to epinephrine (GO:0071871)2.70651327
110positive regulation of smooth muscle cell migration (GO:0014911)2.70131130
111cortical actin cytoskeleton organization (GO:0030866)2.69648191
112positive regulation of osteoblast proliferation (GO:0033690)2.68929371
113blood vessel endothelial cell migration (GO:0043534)2.68238086
114actin filament depolymerization (GO:0030042)2.67612364
115positive regulation of oligodendrocyte differentiation (GO:0048714)2.66055697
116response to dietary excess (GO:0002021)2.65892154
117protein localization to cell surface (GO:0034394)2.65581951
118negative regulation of epithelial cell migration (GO:0010633)2.65538419
119white fat cell differentiation (GO:0050872)2.65211855
120platelet-derived growth factor receptor signaling pathway (GO:0048008)2.63970891
121thioester biosynthetic process (GO:0035384)2.63669313
122acyl-CoA biosynthetic process (GO:0071616)2.63669313
123Leydig cell differentiation (GO:0033327)2.62565121
124branching involved in salivary gland morphogenesis (GO:0060445)2.62408869
125lymph vessel development (GO:0001945)2.62163348
126regulation of lipoprotein metabolic process (GO:0050746)2.60576577
127triglyceride biosynthetic process (GO:0019432)2.60516966
128* angiogenesis (GO:0001525)2.60000211
129blood vessel remodeling (GO:0001974)2.59799510
130* renal filtration (GO:0097205)2.57881398
131mesodermal cell differentiation (GO:0048333)2.57467814
132negative regulation of angiogenesis (GO:0016525)2.56884575
133cell adhesion mediated by integrin (GO:0033627)2.56743590
134endocrine hormone secretion (GO:0060986)2.55998640
135stress fiber assembly (GO:0043149)2.55767870
136regulation of glomerular filtration (GO:0003093)2.55663743
137heart trabecula formation (GO:0060347)2.55416700
138extracellular matrix disassembly (GO:0022617)2.55249863
139long-chain fatty acid biosynthetic process (GO:0042759)2.54841978
140positive regulation of cellular response to insulin stimulus (GO:1900078)2.54257436
141epithelial cell-cell adhesion (GO:0090136)2.53984341
142negative regulation of platelet activation (GO:0010544)2.53687720
143eye photoreceptor cell differentiation (GO:0001754)2.53528590
144photoreceptor cell differentiation (GO:0046530)2.53528590
145nerve growth factor signaling pathway (GO:0038180)2.53057041
146insulin-like growth factor receptor signaling pathway (GO:0048009)2.52894190
147collagen metabolic process (GO:0032963)2.52678639
148* glomerular filtration (GO:0003094)2.52367153
149serine transport (GO:0032329)2.52362152
150embryonic heart tube development (GO:0035050)2.51199500
151cell migration involved in sprouting angiogenesis (GO:0002042)2.50710612
152semaphorin-plexin signaling pathway (GO:0071526)2.49739051
153neutral lipid biosynthetic process (GO:0046460)2.48924262
154acylglycerol biosynthetic process (GO:0046463)2.48924262
155cellular response to catecholamine stimulus (GO:0071870)2.47902654
156cellular response to monoamine stimulus (GO:0071868)2.47902654
157positive regulation of insulin receptor signaling pathway (GO:0046628)2.45845564
158growth hormone receptor signaling pathway (GO:0060396)2.45377145
159response to hepatocyte growth factor (GO:0035728)2.44908701
160cellular response to hepatocyte growth factor stimulus (GO:0035729)2.44908701
161glycerolipid catabolic process (GO:0046503)2.43328896
162hypotonic response (GO:0006971)2.42291454
163polarized epithelial cell differentiation (GO:0030859)2.41806058
164regulation of axon extension involved in axon guidance (GO:0048841)2.38956366
165cortical cytoskeleton organization (GO:0030865)2.38888839
166negative regulation of axon extension involved in axon guidance (GO:0048843)2.38847739
167regulation of receptor binding (GO:1900120)2.38730381
168cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.38531703
169regulation of vasculogenesis (GO:2001212)2.38244606
170cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.37896856
171lipid particle organization (GO:0034389)2.37695701
172collagen fibril organization (GO:0030199)2.36694949
173negative regulation of potassium ion transmembrane transport (GO:1901380)2.36588084
174negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.35447262
175neutral lipid catabolic process (GO:0046461)2.35380533
176acylglycerol catabolic process (GO:0046464)2.35380533

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human4.39523108
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.04669778
3TP63_17297297_ChIP-ChIP_HaCaT_Human2.68666275
4CLOCK_20551151_ChIP-Seq_293T_Human2.57990316
5EP300_21415370_ChIP-Seq_HL-1_Mouse2.46084275
6WT1_19549856_ChIP-ChIP_CCG9911_Human2.40745310
7THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.21253129
8ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.19955224
9* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.19354559
10NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.17763075
11CDX2_19796622_ChIP-Seq_MESCs_Mouse2.08305291
12ESR2_21235772_ChIP-Seq_MCF-7_Human1.95042229
13RARG_19884340_ChIP-ChIP_MEFs_Mouse1.92477268
14SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.92341264
15* RNF2_18974828_ChIP-Seq_MESCs_Mouse1.87528652
16* EZH2_18974828_ChIP-Seq_MESCs_Mouse1.87528652
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.86060264
18TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.82642809
19GATA2_21666600_ChIP-Seq_HMVEC_Human1.79875094
20FOXO3_23340844_ChIP-Seq_DLD1_Human1.77827154
21SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.72172628
22SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.69527858
23KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.68381380
24KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.68381380
25KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.68381380
26SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.68296113
27* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.64169812
28STAT6_21828071_ChIP-Seq_BEAS2B_Human1.62022931
29* PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.61111035
30* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.59885646
31CJUN_26792858_Chip-Seq_BT549_Human1.58918029
32PPAR_26484153_Chip-Seq_NCI-H1993_Human1.57945834
33PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.57485680
34EED_16625203_ChIP-ChIP_MESCs_Mouse1.51386777
35TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50752440
36NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.50401071
37NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.49137652
38TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.48851161
39FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.46728442
40LXR_22292898_ChIP-Seq_THP-1_Human1.44735264
41EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41867306
42UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.41509139
43SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.41471990
44CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.41000240
45EZH2_27304074_Chip-Seq_ESCs_Mouse1.39511390
46* TBX20_22328084_ChIP-Seq_HEART_Mouse1.39453820
47* TBX20_22080862_ChIP-Seq_HEART_Mouse1.39453820
48SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.39187370
49SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.37707147
50TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.36060276
51ZNF217_24962896_ChIP-Seq_MCF-7_Human1.36019255
52* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.36005713
53ESR1_20079471_ChIP-ChIP_T-47D_Human1.35024133
54DROSHA_22980978_ChIP-Seq_HELA_Human1.34225839
55* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.34134272
56GBX2_23144817_ChIP-Seq_PC3_Human1.32562833
57RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.31541975
58PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30068460
59NRF2_20460467_ChIP-Seq_MEFs_Mouse1.29864641
60NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.29864641
61SMC1_22415368_ChIP-Seq_MEFs_Mouse1.27435965
62JARID2_20064375_ChIP-Seq_MESCs_Mouse1.27305659
63TP53_23651856_ChIP-Seq_MEFs_Mouse1.26986474
64UBF1/2_26484160_Chip-Seq_HMECs_Human1.26860279
65* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.26407992
66SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.25345512
67SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.25345512
68SOX9_24532713_ChIP-Seq_HFSC_Mouse1.24812545
69SMC3_22415368_ChIP-Seq_MEFs_Mouse1.24388679
70SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.23693473
71OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23241155
72STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.22865270
73* RACK7_27058665_Chip-Seq_MCF-7_Human1.21424793
74JARID2_20075857_ChIP-Seq_MESCs_Mouse1.21050453
75RNF2_27304074_Chip-Seq_ESCs_Mouse1.21023720
76AHR_22903824_ChIP-Seq_MCF-7_Human1.20068687
77SALL4_18804426_ChIP-ChIP_XEN_Mouse1.19402512
78BRD4_25478319_ChIP-Seq_HGPS_Human1.19030586
79RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.17500447
80TET1_21490601_ChIP-Seq_MESCs_Mouse1.16186672
81KDM2B_26808549_Chip-Seq_K562_Human1.16145711
82BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.15366934
83EZH2_27294783_Chip-Seq_ESCs_Mouse1.14124687
84PIAS1_25552417_ChIP-Seq_VCAP_Human1.14110707
85ISL1_27105846_Chip-Seq_CPCs_Mouse1.13968064
86ZNF263_19887448_ChIP-Seq_K562_Human1.13551408
87KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.12556201
88ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.12491395
89ESR1_21235772_ChIP-Seq_MCF-7_Human1.12181656
90SMAD_19615063_ChIP-ChIP_OVARY_Human1.10807915
91* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.10153197
92TP53_16413492_ChIP-PET_HCT116_Human1.10100785
93SOX2_20726797_ChIP-Seq_SW620_Human1.09677483
94TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.09069978
95SUZ12_27294783_Chip-Seq_ESCs_Mouse1.07170709
96TP53_20018659_ChIP-ChIP_R1E_Mouse1.06925394
97* ELK3_25401928_ChIP-Seq_HUVEC_Human1.05589207
98HIF1A_21447827_ChIP-Seq_MCF-7_Human1.05530901
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.04908355
100ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.04553783
101SA1_22415368_ChIP-Seq_MEFs_Mouse1.02655583
102FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.01258617
103NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.01156292
104CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.01154398
105CTNNB1_20460455_ChIP-Seq_HCT116_Human1.01073613
106LXR_22158963_ChIP-Seq_LIVER_Mouse1.00790408
107PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.00406598
108CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.98189351
109P63_26484246_Chip-Seq_KERATINOCYTES_Human0.96846047
110GATA1_19941826_ChIP-Seq_K562_Human0.96649954
111* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.96580584
112EOMES_21245162_ChIP-Seq_HESCs_Human0.96418432
113* ZFP281_18757296_ChIP-ChIP_E14_Mouse0.96409645
114ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95910973
115JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94863964
116CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.93723615
117RING1B_27294783_Chip-Seq_NPCs_Mouse0.93651023
118ARNT_22903824_ChIP-Seq_MCF-7_Human0.92905742
119PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.92842810
120RXR_22158963_ChIP-Seq_LIVER_Mouse0.92661770
121JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92030446
122* NR3C1_23031785_ChIP-Seq_PC12_Mouse0.91848037
123DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.91700888
124PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.91213933
125VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.90342872
126NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.89109942
127AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.88983941
128* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.88760307
129ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.87962172
130AR_21572438_ChIP-Seq_LNCaP_Human0.87759659
131TP53_22127205_ChIP-Seq_IMR90_Human0.86332464
132NFIB_24661679_ChIP-Seq_LUNG_Mouse0.86284905
133ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.85805340
134ERG_21242973_ChIP-ChIP_JURKAT_Human0.85022264

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004272_abnormal_basement_membrane5.15102109
2MP0008438_abnormal_cutaneous_collagen4.85339899
3MP0003950_abnormal_plasma_membrane3.31093067
4MP0000920_abnormal_myelination2.93957977
5MP0005623_abnormal_meninges_morphology2.90654726
6MP0005275_abnormal_skin_tensile2.75486079
7MP0010368_abnormal_lymphatic_system2.68730252
8MP0004185_abnormal_adipocyte_glucose2.64087904
9MP0005670_abnormal_white_adipose2.61978907
10MP0002877_abnormal_melanocyte_morpholog2.59196438
11MP0000013_abnormal_adipose_tissue2.51066288
12MP0004084_abnormal_cardiac_muscle2.42489991
13MP0000751_myopathy2.34399533
14MP0005666_abnormal_adipose_tissue2.34056452
15MP0005409_darkened_coat_color2.28082853
16MP0003690_abnormal_glial_cell2.21149031
17MP0001879_abnormal_lymphatic_vessel2.18339965
18MP0005375_adipose_tissue_phenotype2.14054185
19MP0004130_abnormal_muscle_cell2.04451330
20MP0006138_congestive_heart_failure2.03279374
21MP0000003_abnormal_adipose_tissue2.01931949
22MP0004036_abnormal_muscle_relaxation2.01705731
23MP0010030_abnormal_orbit_morphology1.95413782
24MP0005171_absent_coat_pigmentation1.91475475
25MP0005257_abnormal_intraocular_pressure1.90969133
26MP0002837_dystrophic_cardiac_calcinosis1.88481856
27MP0001958_emphysema1.85429597
28MP0003279_aneurysm1.84522688
29MP0005167_abnormal_blood-brain_barrier1.73825402
30MP0001661_extended_life_span1.73284698
31MP0003828_pulmonary_edema1.67755901
32MP0005330_cardiomyopathy1.64368050
33MP0008775_abnormal_heart_ventricle1.60883748
34MP0003566_abnormal_cell_adhesion1.58866855
35MP0002295_abnormal_pulmonary_circulatio1.55539020
36MP0003045_fibrosis1.54822758
37MP0003634_abnormal_glial_cell1.47077382
38MP0003705_abnormal_hypodermis_morpholog1.46148488
39MP0000462_abnormal_digestive_system1.43681123
40MP0010678_abnormal_skin_adnexa1.40294544
41MP0004087_abnormal_muscle_fiber1.39440746
42MP0001849_ear_inflammation1.37880705
43MP0005620_abnormal_muscle_contractility1.37591205
44MP0000747_muscle_weakness1.35092772
45MP0002933_joint_inflammation1.33215108
46MP0000383_abnormal_hair_follicle1.31355865
47MP0002972_abnormal_cardiac_muscle1.29526109
48MP0004270_analgesia1.27463152
49MP0001915_intracranial_hemorrhage1.27186852
50MP0003091_abnormal_cell_migration1.24671437
51MP0000537_abnormal_urethra_morphology1.24297334
52MP0000750_abnormal_muscle_regeneration1.23239328
53MP0000749_muscle_degeneration1.22695349
54MP0005023_abnormal_wound_healing1.20942115
55MP0004147_increased_porphyrin_level1.20226573
56MP0001727_abnormal_embryo_implantation1.17331850
57MP0010630_abnormal_cardiac_muscle1.16708485
58MP0002108_abnormal_muscle_morphology1.16444406
59MP0004215_abnormal_myocardial_fiber1.16202170
60MP0005503_abnormal_tendon_morphology1.15959883
61MP0001544_abnormal_cardiovascular_syste1.15900050
62MP0005385_cardiovascular_system_phenoty1.15900050
63MP0000465_gastrointestinal_hemorrhage1.12062337
64MP0003329_amyloid_beta_deposits1.11558550
65MP0000733_abnormal_muscle_development1.08910435
66MP0004233_abnormal_muscle_weight1.08615252
67MP0009384_cardiac_valve_regurgitation1.07663301
68MP0009780_abnormal_chondrocyte_physiolo1.07645753
69MP0006054_spinal_hemorrhage1.05719868
70MP0000767_abnormal_smooth_muscle1.04454431
71MP0000534_abnormal_ureter_morphology1.03946411
72MP0001299_abnormal_eye_distance/1.03336242
73MP0003959_abnormal_lean_body1.02822166
74MP0004885_abnormal_endolymph1.01287737
75MP0004145_abnormal_muscle_electrophysio1.00304487
76MP0000759_abnormal_skeletal_muscle1.00259586
77MP0003868_abnormal_feces_composition0.99528552
78MP0003632_abnormal_nervous_system0.99440370
79MP0005388_respiratory_system_phenotype0.99440337
80MP0002133_abnormal_respiratory_system0.99440337
81MP0002896_abnormal_bone_mineralization0.95726271
82MP0001614_abnormal_blood_vessel0.94519269
83MP0004484_altered_response_of0.93488035
84MP0004085_abnormal_heartbeat0.92771558
85MP0003137_abnormal_impulse_conducting0.91059932
86MP0005595_abnormal_vascular_smooth0.89794706
87MP0004134_abnormal_chest_morphology0.89684938
88MP0002128_abnormal_blood_circulation0.89678721
89MP0002925_abnormal_cardiovascular_devel0.89309388
90MP0003385_abnormal_body_wall0.88331235
91MP0005197_abnormal_uvea_morphology0.84769148
92MP0002971_abnormal_brown_adipose0.84747483
93MP0000467_abnormal_esophagus_morphology0.83920962
94MP0005164_abnormal_response_to0.81799527
95MP0004782_abnormal_surfactant_physiolog0.80983324
96MP0003941_abnormal_skin_development0.80343033
97MP0002970_abnormal_white_adipose0.78728321
98MP0000762_abnormal_tongue_morphology0.78168615
99MP0005369_muscle_phenotype0.75359146
100MP0009115_abnormal_fat_cell0.74593139
101MP0009053_abnormal_anal_canal0.74028287
102MP0002106_abnormal_muscle_physiology0.72632236
103MP0004858_abnormal_nervous_system0.71349908
104MP0001348_abnormal_lacrimal_gland0.70906459
105MP0003937_abnormal_limbs/digits/tail_de0.70296322
106MP0002127_abnormal_cardiovascular_syste0.68933644
107MP0003948_abnormal_gas_homeostasis0.67440581
108MP0005165_increased_susceptibility_to0.66609688
109MP0000249_abnormal_blood_vessel0.66579491
110MP0000778_abnormal_nervous_system0.66430379
111MP0003136_yellow_coat_color0.64938222
112MP0000343_altered_response_to0.64531782
113MP0002932_abnormal_joint_morphology0.64435103
114MP0001485_abnormal_pinna_reflex0.63927769
115MP0005508_abnormal_skeleton_morphology0.63371982
116MP0000266_abnormal_heart_morphology0.63308114
117MP0002332_abnormal_exercise_endurance0.62745138
118MP0002060_abnormal_skin_morphology0.62200110
119MP0001784_abnormal_fluid_regulation0.61842353
120MP0010352_gastrointestinal_tract_polyps0.61360793
121MP0002796_impaired_skin_barrier0.61015273
122MP0002168_other_aberrant_phenotype0.60376315
123MP0003631_nervous_system_phenotype0.59879023
124MP0002269_muscular_atrophy0.59704334
125MP0003724_increased_susceptibility_to0.58293823
126MP0002697_abnormal_eye_size0.57742430

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.42565706
2Muscle fiber splitting (HP:0003555)4.28548929
3Hyporeflexia of lower limbs (HP:0002600)4.14887078
4Broad metatarsal (HP:0001783)4.00267486
5Sensory axonal neuropathy (HP:0003390)3.82615549
6Difficulty running (HP:0009046)3.76495658
7Degeneration of the lateral corticospinal tracts (HP:0002314)3.69336295
8Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.69336295
9Cerebral aneurysm (HP:0004944)3.49945162
10Wrist flexion contracture (HP:0001239)3.45213641
11Insidious onset (HP:0003587)3.44528249
12Termporal pattern (HP:0011008)3.44528249
13Aortic dissection (HP:0002647)3.33223239
14Neurofibrillary tangles (HP:0002185)3.22937242
15Onion bulb formation (HP:0003383)3.21616017
16Ulnar claw (HP:0001178)3.12074859
17Polycythemia (HP:0001901)3.09452852
18Hypoplasia of the iris (HP:0007676)3.09360758
19Shallow orbits (HP:0000586)2.98492600
20Nonimmune hydrops fetalis (HP:0001790)2.94156923
21Esophageal varix (HP:0002040)2.94106298
22Increased variability in muscle fiber diameter (HP:0003557)2.93947228
23Acanthosis nigricans (HP:0000956)2.92942449
24Scapular winging (HP:0003691)2.89360665
25Ankle contracture (HP:0006466)2.86779751
26Segmental peripheral demyelination/remyelination (HP:0003481)2.86175622
27Atrophic scars (HP:0001075)2.84288502
28Protrusio acetabuli (HP:0003179)2.82290852
29Increased connective tissue (HP:0009025)2.76510982
30Peripheral hypomyelination (HP:0007182)2.75126094
31Abnormality of the corticospinal tract (HP:0002492)2.75072950
32Vertebral compression fractures (HP:0002953)2.71994300
33Cervical subluxation (HP:0003308)2.70076646
34Stridor (HP:0010307)2.68579454
35Ectopia lentis (HP:0001083)2.65551701
36Skull defect (HP:0001362)2.63348050
37Foot dorsiflexor weakness (HP:0009027)2.63042773
38Blue sclerae (HP:0000592)2.61378738
39Hematochezia (HP:0002573)2.60368856
40Cerebral inclusion bodies (HP:0100314)2.59370763
41Cerebral hemorrhage (HP:0001342)2.55759320
42Spinal rigidity (HP:0003306)2.55609315
43Aortic aneurysm (HP:0004942)2.53862093
44Abnormality of the foot musculature (HP:0001436)2.52804574
45Hammertoe (HP:0001765)2.51820300
46Spontaneous hematomas (HP:0007420)2.49585647
47Short hallux (HP:0010109)2.48165580
48Type 1 muscle fiber predominance (HP:0003803)2.46323993
49Buphthalmos (HP:0000557)2.42134381
50Alacrima (HP:0000522)2.39248980
51Difficulty climbing stairs (HP:0003551)2.38561713
52Parakeratosis (HP:0001036)2.37193180
53Ulnar bowing (HP:0003031)2.35546877
54Steppage gait (HP:0003376)2.34913736
55Abnormality of skeletal muscle fiber size (HP:0012084)2.33420565
56Dilatation of the ascending aorta (HP:0005111)2.30866610
57Bladder diverticulum (HP:0000015)2.29249004
58Premature skin wrinkling (HP:0100678)2.28899870
59Infantile muscular hypotonia (HP:0008947)2.28622968
60Round ear (HP:0100830)2.27164283
61Aplasia/Hypoplasia of the hallux (HP:0008362)2.26491876
62Coxa vara (HP:0002812)2.25351628
63Neonatal death (HP:0003811)2.24735912
64Trismus (HP:0000211)2.23335177
65Tetraparesis (HP:0002273)2.22499876
66Pulmonary artery stenosis (HP:0004415)2.22098528
67Coronal craniosynostosis (HP:0004440)2.19269702
68Short nail (HP:0001799)2.18630851
69Sudden death (HP:0001699)2.18597910
70Action tremor (HP:0002345)2.15280347
71Wormian bones (HP:0002645)2.15198133
72Distal lower limb muscle weakness (HP:0009053)2.14811506
73Fragile skin (HP:0001030)2.14215658
74Broad face (HP:0000283)2.14145482
75Aortic valve stenosis (HP:0001650)2.13873623
76Stroke (HP:0001297)2.09230713
77Soft skin (HP:0000977)2.07730513
78Pheochromocytoma (HP:0002666)2.06973695
79Reduced subcutaneous adipose tissue (HP:0003758)2.05544252
80Decreased number of peripheral myelinated nerve fibers (HP:0003380)2.05091876
81Hypertriglyceridemia (HP:0002155)2.04048800
82Back pain (HP:0003418)2.02177788
83Vertebral clefting (HP:0008428)2.00637191
84Distal lower limb amyotrophy (HP:0008944)2.00035253
85Gowers sign (HP:0003391)1.98287547
86Hemorrhage of the eye (HP:0011885)1.97968122
87Bronchomalacia (HP:0002780)1.97648223
88Myotonia (HP:0002486)1.97071557
89Joint laxity (HP:0001388)1.95997255
90Myocardial infarction (HP:0001658)1.94186037
91Mildly elevated creatine phosphokinase (HP:0008180)1.94128846
92Lipoatrophy (HP:0100578)1.93855976
93Limited hip movement (HP:0008800)1.93456877
94Adactyly (HP:0009776)1.91264660
95Distal upper limb amyotrophy (HP:0007149)1.90632142
96Upper limb amyotrophy (HP:0009129)1.90632142
97Conjunctival telangiectasia (HP:0000524)1.90446666
98Hemangiomatosis (HP:0007461)1.90123324
99Hip contracture (HP:0003273)1.88697851
100Abnormality of the acetabulum (HP:0003170)1.88459923
101Aneurysm (HP:0002617)1.87908984
102Decreased motor nerve conduction velocity (HP:0003431)1.87766184
103Joint contractures involving the joints of the feet (HP:0100492)1.86650393
104Flexion contracture of toe (HP:0005830)1.86650393
105Venous abnormality (HP:0002624)1.86580838
106Intention tremor (HP:0002080)1.86344087
107Mitral valve prolapse (HP:0001634)1.86271067
108Autoamputation (HP:0001218)1.86212818
109Abnormality of dentin (HP:0010299)1.85033654
110Portal hypertension (HP:0001409)1.84929946
111Hydroureter (HP:0000072)1.84503060
112Hypopigmentation of the fundus (HP:0007894)1.83153649
113Vertebral arch anomaly (HP:0008438)1.82796591
114Aplasia involving bones of the extremities (HP:0009825)1.82285839
115Aplasia involving bones of the upper limbs (HP:0009823)1.82285839
116Aplasia of the phalanges of the hand (HP:0009802)1.82285839
117Venous insufficiency (HP:0005293)1.81649357
118Right ventricular cardiomyopathy (HP:0011663)1.81000603
119Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.80661541
120Abnormal auditory evoked potentials (HP:0006958)1.80421642
121Neck muscle weakness (HP:0000467)1.79957658
122Oligomenorrhea (HP:0000876)1.79530256
123EMG: myopathic abnormalities (HP:0003458)1.79314910
124Supranuclear gaze palsy (HP:0000605)1.79125254
125Osteolytic defects of the hand bones (HP:0009699)1.77899433
126Osteolytic defects of the phalanges of the hand (HP:0009771)1.77899433
127Turricephaly (HP:0000262)1.77773106
128Mitral regurgitation (HP:0001653)1.77720479
129Abnormality of the anterior chamber (HP:0000593)1.77664933
130Overgrowth (HP:0001548)1.77644247
131Wide anterior fontanel (HP:0000260)1.77184024
132Ventricular tachycardia (HP:0004756)1.76525930
133Hypoplastic ischia (HP:0003175)1.76327917
134Hyperextensible skin (HP:0000974)1.76157952
135Camptodactyly of toe (HP:0001836)1.75939749
136Follicular hyperkeratosis (HP:0007502)1.75473103
137Mitral stenosis (HP:0001718)1.75025615
138Genu recurvatum (HP:0002816)1.74977324
139White forelock (HP:0002211)1.74634003
140Visceral angiomatosis (HP:0100761)1.74216131
141Vascular tortuosity (HP:0004948)1.73451787
142Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.73291028
143Bell-shaped thorax (HP:0001591)1.71946912
144Absent hand (HP:0004050)1.71270122
145Lower limb muscle weakness (HP:0007340)1.70845000
146Joint stiffness (HP:0001387)1.70699071
147Abnormality of the hepatic vasculature (HP:0006707)1.70415577
148Abnormal vertebral ossification (HP:0100569)1.69690781
149Ankyloglossia (HP:0010296)1.69503206
150Atrial fibrillation (HP:0005110)1.68718125
151Esophageal atresia (HP:0002032)1.68717564
152Disproportionate tall stature (HP:0001519)1.68145137
153Lymphangioma (HP:0100764)1.67091951
154Arterial tortuosity (HP:0005116)1.66215762
155Peritonitis (HP:0002586)1.66110586

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.00175123
2TIE14.08599756
3EPHB12.96909904
4MET2.96844722
5OXSR12.87925029
6FGFR22.51626767
7TTN2.37973030
8ICK2.33612767
9WNK42.27529617
10LIMK12.23715243
11BCR2.17883299
12MYLK2.10889533
13WNK12.08607241
14NTRK12.07285492
15KDR1.85799476
16EPHB21.84820429
17CAMK1D1.68882486
18DMPK1.68813707
19CAMK1G1.68577958
20PDGFRA1.59948450
21PTK2B1.53594666
22LMTK21.43552230
23DDR21.42368324
24TRIB31.42302706
25TGFBR11.41941990
26EEF2K1.40325354
27PAK31.31875500
28TRPM71.31764153
29CSNK1A1L1.30849499
30ROCK21.29987375
31FES1.29671254
32PRPF4B1.27808860
33CSNK1G31.23016712
34TESK11.21711212
35PKN11.21343970
36TYRO31.21237122
37MAPKAPK31.20351110
38PAK21.16854905
39LATS11.16315673
40TGFBR21.16279620
41PHKG21.12841048
42PHKG11.12841048
43RIPK11.11634999
44CSNK1G11.10846962
45FER1.10515295
46PDGFRB1.10083596
47ERN11.09477141
48PAK61.09341990
49PTK21.05904174
50MAP3K31.01967140
51PRKD11.01567519
52MOS1.01022803
53ARAF0.96117693
54FGR0.94855973
55CDK190.93730718
56UHMK10.92300809
57CSNK1G20.85674568
58FGFR40.84863331
59KSR20.84439758
60MAP3K60.84341299
61ROCK10.81375067
62RET0.80852723
63RPS6KA20.80850682
64BMX0.79185327
65CAMK2D0.78886597
66PNCK0.77475677
67MAPK120.77270165
68MARK20.76459697
69GSK3A0.76395329
70PIK3CA0.76390469
71SIK10.76357555
72ABL20.76353710
73CAMK2B0.71866188
74NEK60.71713212
75PDPK10.70673789
76ILK0.70364841
77PRKD30.68393281
78EPHA20.67195365
79FLT30.66260895
80PRKCH0.66162297
81MST1R0.65927044
82MAPKAPK50.62812502
83PKN20.62166978
84NEK90.60111446
85LRRK20.60061943
86MAP2K10.59071977
87CAMK2G0.58702212
88MAPK70.58059546
89INSR0.57888855
90MTOR0.57314364
91CLK10.55858777
92CDK140.55598119
93CSK0.55204547
94FGFR10.52519972
95PRKAA20.52077052
96MAP2K20.51624006
97PDK20.51560731
98PBK0.51264848
99MAPK150.50805302
100PTK60.49940358
101SMG10.48824680
102CDC42BPA0.48051584
103FYN0.46413877
104PRKCE0.46213404
105GRK50.45030182
106MAP3K20.44998614
107STK380.44760101
108MAP3K130.44257174
109IRAK30.44007275
110SRC0.43125697
111CDK50.41970191
112PAK40.41629664
113MAPK40.41620132
114PAK10.41541205
115MAP2K30.41047386
116DAPK30.40972374
117PRKG20.40246841
118OBSCN0.40179154
119INSRR0.38489628
120CAMK10.38138876
121EPHA30.37779398
122ERBB40.37451726
123STK110.37227035
124ZAP700.36240985
125KIT0.36238531
126LATS20.35479650
127AKT20.34648653
128PRKACB0.34172450
129PRKAA10.33792339
130CDK150.33382804
131STK100.31892153
132PIM20.31605551
133PRKD20.31348200
134MAP3K10.31325545
135NTRK30.30959448
136MAP3K70.30739714
137IGF1R0.28650334
138ADRBK10.28083501
139CDK90.26594104
140CDK60.21121320
141PIK3CG0.20824095
142MARK10.20484376

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.34600310
2Regulation of lipolysis in adipocytes_Homo sapiens_hsa049233.15792951
3Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.70642179
4Fatty acid elongation_Homo sapiens_hsa000622.50871927
5Glycosaminoglycan degradation_Homo sapiens_hsa005312.40760047
6Focal adhesion_Homo sapiens_hsa045102.33329586
7Axon guidance_Homo sapiens_hsa043602.11504314
8Fatty acid biosynthesis_Homo sapiens_hsa000612.07323356
9Tight junction_Homo sapiens_hsa045302.02677925
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.90861391
11Dilated cardiomyopathy_Homo sapiens_hsa054141.90142377
12Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.74626601
13Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.74467313
14Dorso-ventral axis formation_Homo sapiens_hsa043201.72879608
15Propanoate metabolism_Homo sapiens_hsa006401.69154899
16PPAR signaling pathway_Homo sapiens_hsa033201.67483346
17Steroid biosynthesis_Homo sapiens_hsa001001.65086344
18Fatty acid metabolism_Homo sapiens_hsa012121.61560791
19Protein digestion and absorption_Homo sapiens_hsa049741.60446784
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.56090334
21Renal cell carcinoma_Homo sapiens_hsa052111.49940572
22Ether lipid metabolism_Homo sapiens_hsa005651.45749948
23Vascular smooth muscle contraction_Homo sapiens_hsa042701.40921782
24Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.37733503
25Proteoglycans in cancer_Homo sapiens_hsa052051.36392362
26Prion diseases_Homo sapiens_hsa050201.34136316
27Amoebiasis_Homo sapiens_hsa051461.32401253
28Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.31324404
29Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.28450647
30Regulation of actin cytoskeleton_Homo sapiens_hsa048101.27648511
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.25461489
32PI3K-Akt signaling pathway_Homo sapiens_hsa041511.25373378
33Glycerolipid metabolism_Homo sapiens_hsa005611.22511372
34Leukocyte transendothelial migration_Homo sapiens_hsa046701.21479591
35Hippo signaling pathway_Homo sapiens_hsa043901.20567635
36Adherens junction_Homo sapiens_hsa045201.15949002
37Phenylalanine metabolism_Homo sapiens_hsa003601.12382289
38Complement and coagulation cascades_Homo sapiens_hsa046101.12045780
39TGF-beta signaling pathway_Homo sapiens_hsa043501.08821401
40Hedgehog signaling pathway_Homo sapiens_hsa043401.08319302
41Endocytosis_Homo sapiens_hsa041441.08189872
42Phospholipase D signaling pathway_Homo sapiens_hsa040721.07564031
43Renin secretion_Homo sapiens_hsa049241.06834064
44Small cell lung cancer_Homo sapiens_hsa052221.06199103
45AMPK signaling pathway_Homo sapiens_hsa041521.02135017
46Adipocytokine signaling pathway_Homo sapiens_hsa049200.99583125
47Bladder cancer_Homo sapiens_hsa052190.97996930
48Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.97056500
49Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.96996738
50Chronic myeloid leukemia_Homo sapiens_hsa052200.93904166
51Ras signaling pathway_Homo sapiens_hsa040140.93656768
52Rap1 signaling pathway_Homo sapiens_hsa040150.93064292
53Aldosterone synthesis and secretion_Homo sapiens_hsa049250.91284341
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.91251273
55Basal cell carcinoma_Homo sapiens_hsa052170.90670395
56Sphingolipid signaling pathway_Homo sapiens_hsa040710.90669725
57Glioma_Homo sapiens_hsa052140.89385991
58cGMP-PKG signaling pathway_Homo sapiens_hsa040220.87166991
59AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.86407993
60Cardiac muscle contraction_Homo sapiens_hsa042600.86032832
61Ovarian steroidogenesis_Homo sapiens_hsa049130.85253201
62Malaria_Homo sapiens_hsa051440.85247258
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.84240502
64Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.83385725
65Arginine biosynthesis_Homo sapiens_hsa002200.82710423
66Gap junction_Homo sapiens_hsa045400.82365541
67Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.81106445
68Platelet activation_Homo sapiens_hsa046110.79601609
69Insulin signaling pathway_Homo sapiens_hsa049100.78969820
70Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.76609476
71Notch signaling pathway_Homo sapiens_hsa043300.76512664
72Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76240375
73Sphingolipid metabolism_Homo sapiens_hsa006000.75972495
74Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75359156
75Pathways in cancer_Homo sapiens_hsa052000.74890019
76GnRH signaling pathway_Homo sapiens_hsa049120.74654182
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.72593768
78HIF-1 signaling pathway_Homo sapiens_hsa040660.72436116
79Tyrosine metabolism_Homo sapiens_hsa003500.71728671
80Butanoate metabolism_Homo sapiens_hsa006500.70718725
81Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.70168104
82Viral myocarditis_Homo sapiens_hsa054160.70113905
83cAMP signaling pathway_Homo sapiens_hsa040240.69902757
84Fatty acid degradation_Homo sapiens_hsa000710.69455452
85VEGF signaling pathway_Homo sapiens_hsa043700.68995037
86Linoleic acid metabolism_Homo sapiens_hsa005910.68746968
87Sulfur metabolism_Homo sapiens_hsa009200.67463210
88Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65871490
89Central carbon metabolism in cancer_Homo sapiens_hsa052300.65631960
90Pancreatic cancer_Homo sapiens_hsa052120.64710466
91ErbB signaling pathway_Homo sapiens_hsa040120.64557559
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63160869
93Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63133113
94Thyroid cancer_Homo sapiens_hsa052160.63123534
95Longevity regulating pathway - mammal_Homo sapiens_hsa042110.62725508
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62351679
97Melanogenesis_Homo sapiens_hsa049160.61950100
98Sulfur relay system_Homo sapiens_hsa041220.60663970
99Wnt signaling pathway_Homo sapiens_hsa043100.60455266
1002-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58911477
101Other glycan degradation_Homo sapiens_hsa005110.58769347
102Pyruvate metabolism_Homo sapiens_hsa006200.58329456
103Bile secretion_Homo sapiens_hsa049760.58173654
104Long-term depression_Homo sapiens_hsa047300.57898091
105MicroRNAs in cancer_Homo sapiens_hsa052060.57630710
106Lysine degradation_Homo sapiens_hsa003100.56825003
107Estrogen signaling pathway_Homo sapiens_hsa049150.56740961
108Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.55692920
109Gastric acid secretion_Homo sapiens_hsa049710.54335407
110Choline metabolism in cancer_Homo sapiens_hsa052310.53439902
111Arginine and proline metabolism_Homo sapiens_hsa003300.52920274
112Oxytocin signaling pathway_Homo sapiens_hsa049210.52513484
113Salivary secretion_Homo sapiens_hsa049700.51915118
114Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.51514550
115Fat digestion and absorption_Homo sapiens_hsa049750.49917457
116Insulin resistance_Homo sapiens_hsa049310.49616815
117Neurotrophin signaling pathway_Homo sapiens_hsa047220.48385839
118Prostate cancer_Homo sapiens_hsa052150.47227617
119Thyroid hormone synthesis_Homo sapiens_hsa049180.46230522
120Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.45642337
121Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45368937
122Oxidative phosphorylation_Homo sapiens_hsa001900.45135269
123Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44878528
124Alzheimers disease_Homo sapiens_hsa050100.44718760
125Histidine metabolism_Homo sapiens_hsa003400.43516097
126Autoimmune thyroid disease_Homo sapiens_hsa053200.43465960
127Glycerophospholipid metabolism_Homo sapiens_hsa005640.43434101
128Glucagon signaling pathway_Homo sapiens_hsa049220.42794847
129Vibrio cholerae infection_Homo sapiens_hsa051100.42728756
130Pancreatic secretion_Homo sapiens_hsa049720.42567961
131Melanoma_Homo sapiens_hsa052180.42421232
132Parkinsons disease_Homo sapiens_hsa050120.42384300
133Salmonella infection_Homo sapiens_hsa051320.39932959
134Serotonergic synapse_Homo sapiens_hsa047260.39219140

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