MCTP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)5.24094353
2positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.08089856
3regulation of synapse structural plasticity (GO:0051823)5.02799416
4locomotory exploration behavior (GO:0035641)4.93781180
5response to peptidoglycan (GO:0032494)4.86396701
6regulation of short-term neuronal synaptic plasticity (GO:0048172)4.80094702
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.73552125
8regulation of long-term neuronal synaptic plasticity (GO:0048169)4.52794288
9ionotropic glutamate receptor signaling pathway (GO:0035235)4.46236123
10synaptic vesicle maturation (GO:0016188)4.43290447
11regulation of glutamate receptor signaling pathway (GO:1900449)4.43092064
12negative regulation of interleukin-12 production (GO:0032695)4.41004493
13detection of molecule of bacterial origin (GO:0032490)4.39076661
14positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)4.35048926
15macrophage activation involved in immune response (GO:0002281)4.27305484
16synaptic vesicle exocytosis (GO:0016079)4.27118046
17positive regulation of gamma-delta T cell activation (GO:0046645)4.21860764
18immunoglobulin mediated immune response (GO:0016064)4.21793913
19positive regulation by symbiont of host defense response (GO:0052509)4.12756892
20modulation by symbiont of host defense response (GO:0052031)4.12756892
21modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.12756892
22modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.12756892
23positive regulation by organism of defense response of other organism involved in symbiotic interact4.12756892
24modulation by symbiont of host immune response (GO:0052553)4.12756892
25vocalization behavior (GO:0071625)4.04133263
26prepulse inhibition (GO:0060134)4.03000858
27microglial cell activation (GO:0001774)4.01932695
28positive regulation of mast cell activation (GO:0033005)3.99215856
29regulation of neuronal synaptic plasticity (GO:0048168)3.94694059
30synaptic transmission, glutamatergic (GO:0035249)3.83020343
31cellular extravasation (GO:0045123)3.81541709
32regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.78808548
33neuron-neuron synaptic transmission (GO:0007270)3.78614799
34synaptic transmission, dopaminergic (GO:0001963)3.77705933
35macrophage activation (GO:0042116)3.75615455
36neuronal action potential propagation (GO:0019227)3.74131843
37regulation of excitatory postsynaptic membrane potential (GO:0060079)3.73116481
38exploration behavior (GO:0035640)3.72516901
39glutamate receptor signaling pathway (GO:0007215)3.72450161
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.70177987
41regulation of synaptic vesicle exocytosis (GO:2000300)3.69714883
42lipopolysaccharide-mediated signaling pathway (GO:0031663)3.66695581
43positive regulation of mast cell degranulation (GO:0043306)3.66408741
44positive regulation of mast cell activation involved in immune response (GO:0033008)3.66408741
45neurotransmitter-gated ion channel clustering (GO:0072578)3.63203462
46positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.63019289
47protein localization to synapse (GO:0035418)3.62534245
48regulation of synaptic vesicle transport (GO:1902803)3.61795109
49neutrophil activation (GO:0042119)3.58324729
50mast cell activation involved in immune response (GO:0002279)3.56786326
51mast cell degranulation (GO:0043303)3.56786326
52positive regulation of membrane potential (GO:0045838)3.55814784
53synaptic vesicle docking involved in exocytosis (GO:0016081)3.54429360
54detection of other organism (GO:0098543)3.53953508
55G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.53914604
56detection of external biotic stimulus (GO:0098581)3.49444289
57granulocyte activation (GO:0036230)3.49159280
58long-term memory (GO:0007616)3.48040100
59neurotransmitter secretion (GO:0007269)3.47791472
60positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.47275711
61regulation of mast cell activation (GO:0033003)3.47208208
62B cell mediated immunity (GO:0019724)3.43302021
63positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.41223707
64regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.40113847
65regulation of postsynaptic membrane potential (GO:0060078)3.39621135
66response to histamine (GO:0034776)3.37288116
67response to amphetamine (GO:0001975)3.36946254
68synaptic vesicle endocytosis (GO:0048488)3.35835188
69T-helper 1 type immune response (GO:0042088)3.35453677
70striatum development (GO:0021756)3.34278720
71regulation of synaptic transmission, glutamatergic (GO:0051966)3.33385072
72cellular response to ethanol (GO:0071361)3.33058483
73regulation of mast cell degranulation (GO:0043304)3.32668205
74adenosine receptor signaling pathway (GO:0001973)3.30298676
75regulation of mast cell activation involved in immune response (GO:0033006)3.29901537
76gamma-aminobutyric acid transport (GO:0015812)3.28043156
77adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.26571189
78positive regulation of neurotransmitter secretion (GO:0001956)3.26194878
79positive regulation of neurotransmitter transport (GO:0051590)3.24528944
80proline transport (GO:0015824)3.23790307
81glutamate secretion (GO:0014047)3.23275781
82regulation of interferon-beta biosynthetic process (GO:0045357)3.23106499
83regulation of T-helper 1 cell differentiation (GO:0045625)3.23090532
84positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.22724275
85mast cell activation (GO:0045576)3.22098560
86response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.20624818
87response to host immune response (GO:0052572)3.20624818
88interferon-gamma-mediated signaling pathway (GO:0060333)3.19858851
89positive regulation of synaptic transmission, GABAergic (GO:0032230)3.18691622
90germinal center formation (GO:0002467)3.15610364
91negative regulation of interleukin-17 production (GO:0032700)3.15076770
92regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.12696023
93neuromuscular process controlling balance (GO:0050885)3.10857910
94regulation of synaptic plasticity (GO:0048167)3.09522925
95neutrophil mediated immunity (GO:0002446)3.08182574
96regulation of interferon-alpha production (GO:0032647)3.08148920
97detection of biotic stimulus (GO:0009595)3.07555721
98auditory behavior (GO:0031223)3.06340116
99regulation of dendritic spine morphogenesis (GO:0061001)3.04385382
100negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.02852720
101negative regulation of dendrite development (GO:2000171)3.02739410
102positive regulation of myeloid leukocyte mediated immunity (GO:0002888)3.01276827
103positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.01208131
104regulation of B cell receptor signaling pathway (GO:0050855)3.00884695
105defense response to protozoan (GO:0042832)3.00793732
106positive regulation of type 2 immune response (GO:0002830)3.00654331
107detection of bacterium (GO:0016045)2.99179738
108regulation of T-helper 2 cell differentiation (GO:0045628)2.98509690
109long-term synaptic potentiation (GO:0060291)2.97558089
110mature B cell differentiation involved in immune response (GO:0002313)2.97548953
111dopamine receptor signaling pathway (GO:0007212)2.97520665
112regulation of dendritic cell antigen processing and presentation (GO:0002604)2.96873427
113response to auditory stimulus (GO:0010996)2.96707707
114cAMP catabolic process (GO:0006198)2.96148257
115neuron cell-cell adhesion (GO:0007158)2.95625164
116behavioral response to cocaine (GO:0048148)2.93377840
117gamma-aminobutyric acid signaling pathway (GO:0007214)2.92380017
118positive regulation of interferon-alpha production (GO:0032727)2.92295031
119B cell receptor signaling pathway (GO:0050853)2.92291757
120visual learning (GO:0008542)2.91810916
121negative regulation of dendrite morphogenesis (GO:0050774)2.91501020
122activation of protein kinase A activity (GO:0034199)2.90423636
123regulation of myeloid leukocyte mediated immunity (GO:0002886)2.89610577
124positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.89467849
125response to muramyl dipeptide (GO:0032495)2.89158283
126membrane depolarization (GO:0051899)2.88930720
127regulation of voltage-gated calcium channel activity (GO:1901385)2.88674861
128regulation of interleukin-17 production (GO:0032660)2.88189272
129antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.87902640
130positive regulation of leukocyte degranulation (GO:0043302)2.87365192
131behavioral defense response (GO:0002209)2.86720990
132behavioral fear response (GO:0001662)2.86720990
133regulation of glutamate secretion (GO:0014048)2.86607522
134regulation of platelet activation (GO:0010543)2.86194730
135response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.85504262
136response to host (GO:0075136)2.85504262
137response to host defenses (GO:0052200)2.85504262
138regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.84509633
139myeloid leukocyte activation (GO:0002274)2.84411885
140positive regulation of toll-like receptor signaling pathway (GO:0034123)2.83540983
141regulation of leukocyte degranulation (GO:0043300)2.82932992
142regulation of interleukin-8 biosynthetic process (GO:0045414)2.81915917
143response to protozoan (GO:0001562)2.80864389
144regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.80798326
145regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.80798326
146regulation of neurotransmitter levels (GO:0001505)2.80304748
147transmission of nerve impulse (GO:0019226)2.80257869
148mechanosensory behavior (GO:0007638)2.78650810
149regulation of neurotransmitter secretion (GO:0046928)2.78609559
150regulation of protein kinase A signaling (GO:0010738)2.78113949
151regulation of neurotransmitter transport (GO:0051588)2.77236077
152superoxide anion generation (GO:0042554)2.75734768
153positive regulation of interleukin-6 production (GO:0032755)2.75042371
154neurotransmitter transport (GO:0006836)2.74877630
155positive regulation of macrophage cytokine production (GO:0060907)2.74576072
156positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.74212744
157learning (GO:0007612)2.73520824
158regulation of macrophage cytokine production (GO:0010935)2.73359297
159endothelium development (GO:0003158)2.73274976
160regulation of MHC class II biosynthetic process (GO:0045346)2.71981414
161regulation of gamma-delta T cell activation (GO:0046643)2.71923301
162myeloid leukocyte mediated immunity (GO:0002444)2.71728605
163neutrophil chemotaxis (GO:0030593)2.71305611
164negative regulation of T-helper cell differentiation (GO:0045623)2.71148155
165negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.71148155
166positive regulation of B cell differentiation (GO:0045579)2.70604170
167leukocyte migration involved in inflammatory response (GO:0002523)2.69831149
168negative regulation of synaptic transmission, GABAergic (GO:0032229)2.69706813
169negative regulation of cell killing (GO:0031342)2.69503463
170negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.69503463
171phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.69426588
172regulation of tolerance induction (GO:0002643)2.68799384
173histamine secretion (GO:0001821)2.67579933
174regulation of antigen processing and presentation (GO:0002577)2.67417311
175postsynaptic membrane organization (GO:0001941)2.67336549
176visual behavior (GO:0007632)2.67266656
177cellular potassium ion homeostasis (GO:0030007)2.67053934
178regulation of dendritic spine development (GO:0060998)2.66759885
179membrane depolarization during action potential (GO:0086010)2.64845247
180neutrophil migration (GO:1990266)2.63784449
181regulation of vesicle fusion (GO:0031338)2.63738029
182myeloid cell activation involved in immune response (GO:0002275)2.63198483
183negative regulation of amino acid transport (GO:0051956)2.62950107
184positive regulation of interleukin-10 production (GO:0032733)2.62872175
185positive regulation of synaptic transmission (GO:0050806)2.62310369
186fear response (GO:0042596)2.61935459
187regulation of synaptic transmission, GABAergic (GO:0032228)2.61211558
188T cell migration (GO:0072678)2.60257810
189leukocyte degranulation (GO:0043299)2.59844027
190positive regulation of cellular amide metabolic process (GO:0034250)2.57512674
191positive regulation of interferon-beta production (GO:0032728)2.57147690
192adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli2.56927335
193positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)2.56702641
194positive regulation of interleukin-1 beta secretion (GO:0050718)2.56185256
195regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.56008180

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.62434542
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.61154195
3GBX2_23144817_ChIP-Seq_PC3_Human3.54849928
4IKZF1_21737484_ChIP-ChIP_HCT116_Human2.94416315
5RARB_27405468_Chip-Seq_BRAIN_Mouse2.70628495
6MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.62900159
7* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.58066623
8BP1_19119308_ChIP-ChIP_Hs578T_Human2.51676653
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.51298862
10SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.46084018
11DROSHA_22980978_ChIP-Seq_HELA_Human2.40963534
12IRF8_21731497_ChIP-ChIP_J774_Mouse2.40794203
13REST_21632747_ChIP-Seq_MESCs_Mouse2.30276902
14STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.29905801
15BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.28057007
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.24237782
17SCL_19346495_ChIP-Seq_HPC-7_Human2.11035320
18* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.07528901
19* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.03640846
20JARID2_20075857_ChIP-Seq_MESCs_Mouse2.01920654
21MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.99297683
22RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.99074560
23TAF15_26573619_Chip-Seq_HEK293_Human1.97634621
24EGR1_19374776_ChIP-ChIP_THP-1_Human1.97389260
25SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.97282580
26SMAD_19615063_ChIP-ChIP_OVARY_Human1.95573069
27RNF2_18974828_ChIP-Seq_MESCs_Mouse1.94242755
28EZH2_18974828_ChIP-Seq_MESCs_Mouse1.94242755
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.93310131
30* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.91660212
31STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.88629139
32* SPI1_23547873_ChIP-Seq_NB4_Human1.85647727
33SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.80301832
34AR_21572438_ChIP-Seq_LNCaP_Human1.79905198
35REST_18959480_ChIP-ChIP_MESCs_Mouse1.79615012
36STAT4_19710469_ChIP-ChIP_TH1__Mouse1.77897006
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.74847838
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.74839549
39SUZ12_27294783_Chip-Seq_ESCs_Mouse1.73549945
40MYB_26560356_Chip-Seq_TH2_Human1.69505518
41FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.66676131
42SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.65022626
43VDR_24763502_ChIP-Seq_THP-1_Human1.63720163
44BRD4_27068464_Chip-Seq_AML-cells_Mouse1.62777965
45IRF8_27001747_Chip-Seq_BMDM_Mouse1.61158391
46IRF8_22096565_ChIP-ChIP_GC-B_Human1.60313056
47EZH2_27304074_Chip-Seq_ESCs_Mouse1.59779299
48* RNF2_27304074_Chip-Seq_ESCs_Mouse1.58258513
49* EZH2_27294783_Chip-Seq_ESCs_Mouse1.58187641
50CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.57895395
51SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.56067544
52LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.55317872
53SPI1_23127762_ChIP-Seq_K562_Human1.55141316
54SMAD4_21799915_ChIP-Seq_A2780_Human1.52566392
55CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.51732953
56MYB_21317192_ChIP-Seq_ERMYB_Mouse1.50990715
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.48065859
58P300_19829295_ChIP-Seq_ESCs_Human1.44640326
59PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.43654023
60Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.40908720
61NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.40037430
62CTBP2_25329375_ChIP-Seq_LNCAP_Human1.38577793
63GATA3_26560356_Chip-Seq_TH2_Human1.38396320
64* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.35979140
65CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.35412255
66RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.33497597
67PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.31786927
68GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.30834568
69IGF1R_20145208_ChIP-Seq_DFB_Human1.30277698
70* AR_25329375_ChIP-Seq_VCAP_Human1.29809903
71* PU_27001747_Chip-Seq_BMDM_Mouse1.29539371
72EED_16625203_ChIP-ChIP_MESCs_Mouse1.28267311
73GATA3_27048872_Chip-Seq_THYMUS_Human1.27980017
74CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.27621742
75GATA1_19941826_ChIP-Seq_K562_Human1.26880758
76EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.24678784
77MYB_26560356_Chip-Seq_TH1_Human1.24112430
78NRF2_20460467_ChIP-Seq_MEFs_Mouse1.21667663
79NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.21667663
80TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.19022153
81RUNX1_22412390_ChIP-Seq_EML_Mouse1.18375782
82NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.18151031
83CTBP1_25329375_ChIP-Seq_LNCAP_Human1.18116059
84IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.16004673
85TP53_16413492_ChIP-PET_HCT116_Human1.14623508
86GATA2_19941826_ChIP-Seq_K562_Human1.13244772
87GATA1_22025678_ChIP-Seq_K562_Human1.12266706
88TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12127668
89P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12114509
90GATA2_21666600_ChIP-Seq_HMVEC_Human1.10942597
91NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.10443075
92STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.09035465
93DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08823624
94NR3C1_23031785_ChIP-Seq_PC12_Mouse1.08761717
95SMAD3_21741376_ChIP-Seq_EPCs_Human1.08692989
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08678811
97GATA1_19941827_ChIP-Seq_MEL_Mouse1.07342572
98RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.07031200
99CDX2_19796622_ChIP-Seq_MESCs_Mouse1.06334746
100ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.05882005
101GATA1_19941827_ChIP-Seq_MEL86_Mouse1.05500130
102* SOX2_21211035_ChIP-Seq_LN229_Gbm1.05366394
103* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.04293185
104LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.03985888
105BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.03946881
106* STAT3_23295773_ChIP-Seq_U87_Human1.03218474
107RUNX_20019798_ChIP-Seq_JUKART_Human1.02734354
108PRDM14_20953172_ChIP-Seq_ESCs_Human1.02701611
109GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01430623
110ERG_21242973_ChIP-ChIP_JURKAT_Human1.01121183
111STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.00290839
112* TCF4_23295773_ChIP-Seq_U87_Human0.99834312
113RXR_22108803_ChIP-Seq_LS180_Human0.99217560
114IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.98208727
115OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98033016
116RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.97948443
117TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95609381
118GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.95560949
119TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94413556
120WT1_25993318_ChIP-Seq_PODOCYTE_Human0.93791230
121FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.93206942
122RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.92526123
123SMRT_27268052_Chip-Seq_Bcells_Human0.91164384
124GATA2_22383799_ChIP-Seq_G1ME_Mouse0.90751844
125NANOG_18555785_Chip-Seq_ESCs_Mouse0.90375227
126E2F1_18555785_Chip-Seq_ESCs_Mouse0.89933045
127RUNX2_22187159_ChIP-Seq_PCA_Human0.89775292
128E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.89432728
129VDR_24787735_ChIP-Seq_THP-1_Human0.89046665
130JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89038062
131NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.88426215
132TOP2B_26459242_ChIP-Seq_MCF-7_Human0.88386754
133NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.87968732
134CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.87932321
135UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.87477138
136MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.87231549
137MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.86858440
138SMAD3_21741376_ChIP-Seq_ESCs_Human0.86402299
139P53_22387025_ChIP-Seq_ESCs_Mouse0.85868421
140MAF_26560356_Chip-Seq_TH1_Human0.85706159
141SALL4_22934838_ChIP-ChIP_CD34+_Human0.85560029
142AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.85257337
143FLI1_27457419_Chip-Seq_LIVER_Mouse0.85164909
144EZH2_27294783_Chip-Seq_NPCs_Mouse0.84398533
145SALL4_18804426_ChIP-ChIP_XEN_Mouse0.84099421
146CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.83965741
147CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.83921469
148SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.81775649
149CJUN_26792858_Chip-Seq_BT549_Human0.80208585
150ZNF217_24962896_ChIP-Seq_MCF-7_Human0.79024573
151JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.78970772
152* FLI1_21867929_ChIP-Seq_TH2_Mouse0.77703452
153ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.77471516
154SUZ12_18555785_Chip-Seq_ESCs_Mouse0.75223487
155KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.74525132
156OCT4_21477851_ChIP-Seq_ESCs_Mouse0.74322827

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.72913619
2MP0002822_catalepsy4.31311893
3MP0003635_abnormal_synaptic_transmissio3.61003447
4MP0003880_abnormal_central_pattern3.54172052
5MP0009745_abnormal_behavioral_response3.26935894
6MP0009046_muscle_twitch2.99074613
7MP0002063_abnormal_learning/memory/cond2.94470208
8MP0001968_abnormal_touch/_nociception2.85423292
9MP0002064_seizures2.73690153
10MP0000569_abnormal_digit_pigmentation2.67354024
11MP0006082_CNS_inflammation2.52786238
12MP0002572_abnormal_emotion/affect_behav2.47805261
13MP0004270_analgesia2.40524983
14MP0003828_pulmonary_edema2.26100398
15MP0002736_abnormal_nociception_after2.25661120
16MP0009764_decreased_sensitivity_to2.20374813
17MP0002272_abnormal_nervous_system2.16990422
18MP0001486_abnormal_startle_reflex2.13397619
19MP0000465_gastrointestinal_hemorrhage2.11096160
20MP0001501_abnormal_sleep_pattern2.10799489
21MP0005423_abnormal_somatic_nervous2.05621456
22MP0008569_lethality_at_weaning2.02377268
23MP0002735_abnormal_chemical_nociception2.02137726
24MP0001188_hyperpigmentation1.95008948
25MP0005451_abnormal_body_composition1.94034001
26MP0008004_abnormal_stomach_pH1.92303883
27MP0003075_altered_response_to1.89251194
28MP0002734_abnormal_mechanical_nocicepti1.86387561
29MP0000343_altered_response_to1.83253051
30MP0005646_abnormal_pituitary_gland1.81835244
31MP0003300_gastrointestinal_ulcer1.80075562
32MP0005174_abnormal_tail_pigmentation1.79572986
33MP0003172_abnormal_lysosome_physiology1.77304881
34MP0001835_abnormal_antigen_presentation1.76164768
35MP0001970_abnormal_pain_threshold1.75352670
36MP0002733_abnormal_thermal_nociception1.74358714
37MP0005464_abnormal_platelet_physiology1.67479043
38MP0003191_abnormal_cellular_cholesterol1.66513330
39MP0003879_abnormal_hair_cell1.65634373
40MP0005386_behavior/neurological_phenoty1.65185242
41MP0004924_abnormal_behavior1.65185242
42MP0002067_abnormal_sensory_capabilities1.63151970
43MP0005409_darkened_coat_color1.63094571
44MP0001533_abnormal_skeleton_physiology1.62774358
45MP0003656_abnormal_erythrocyte_physiolo1.60279457
46MP0004510_myositis1.60236426
47MP0003183_abnormal_peptide_metabolism1.60160189
48MP0005167_abnormal_blood-brain_barrier1.58093447
49MP0002405_respiratory_system_inflammati1.56931448
50MP0001529_abnormal_vocalization1.55994283
51MP0004147_increased_porphyrin_level1.54079627
52MP0001845_abnormal_inflammatory_respons1.52359091
53MP0009278_abnormal_bone_marrow1.51713883
54MP0003303_peritoneal_inflammation1.51630008
55MP0010155_abnormal_intestine_physiology1.49380110
56MP0001440_abnormal_grooming_behavior1.48768128
57MP0009785_altered_susceptibility_to1.47444580
58MP0004811_abnormal_neuron_physiology1.47441848
59MP0005083_abnormal_biliary_tract1.47269333
60MP0006054_spinal_hemorrhage1.47169422
61MP0001853_heart_inflammation1.46989431
62MP0002909_abnormal_adrenal_gland1.44955390
63MP0003633_abnormal_nervous_system1.43429854
64MP0008874_decreased_physiological_sensi1.42576164
65MP0004947_skin_inflammation1.42503154
66MP0000015_abnormal_ear_pigmentation1.40972503
67MP0002419_abnormal_innate_immunity1.40032288
68MP0002332_abnormal_exercise_endurance1.38439348
69MP0001986_abnormal_taste_sensitivity1.36399460
70MP0001905_abnormal_dopamine_level1.35780965
71MP0002557_abnormal_social/conspecific_i1.28687163
72MP0002998_abnormal_bone_remodeling1.27443171
73MP0008469_abnormal_protein_level1.27356722
74MP0003436_decreased_susceptibility_to1.26121537
75MP0002148_abnormal_hypersensitivity_rea1.19973106
76MP0005671_abnormal_response_to1.19196562
77MP0001984_abnormal_olfaction1.18705458
78MP0003448_altered_tumor_morphology1.15756428
79MP0008872_abnormal_physiological_respon1.13273491
80MP0005025_abnormal_response_to1.13036295
81MP0005164_abnormal_response_to1.12699504
82MP0000689_abnormal_spleen_morphology1.12689302
83MP0005000_abnormal_immune_tolerance1.12331255
84MP0001851_eye_inflammation1.12033794
85MP0004858_abnormal_nervous_system1.11586023
86MP0002429_abnormal_blood_cell1.10642292
87MP0003631_nervous_system_phenotype1.08074604
88MP0000249_abnormal_blood_vessel1.06086317
89MP0002722_abnormal_immune_system1.04654151
90MP0004142_abnormal_muscle_tone1.04087418
91MP0008260_abnormal_autophagy1.02643627
92MP0002184_abnormal_innervation1.01902896
93MP0003724_increased_susceptibility_to1.01380135
94MP0002066_abnormal_motor_capabilities/c1.01279147
95MP0005166_decreased_susceptibility_to1.00906566
96MP0009763_increased_sensitivity_to1.00283942
97MP0004883_abnormal_blood_vessel0.99541178
98MP0002877_abnormal_melanocyte_morpholog0.99414732
99MP0008057_abnormal_DNA_replication0.99024700
100MP0004484_altered_response_of0.98027095
101MP0001819_abnormal_immune_cell0.97869235
102MP0002420_abnormal_adaptive_immunity0.97180099
103MP0003091_abnormal_cell_migration0.96475486
104MP0009780_abnormal_chondrocyte_physiolo0.96249905
105MP0003763_abnormal_thymus_physiology0.95393787
106MP0000858_altered_metastatic_potential0.95343639
107MP0002095_abnormal_skin_pigmentation0.95299597
108MP0002452_abnormal_antigen_presenting0.94943509
109MP0002396_abnormal_hematopoietic_system0.94568546
110MP0002723_abnormal_immune_serum0.94330657
111MP0005310_abnormal_salivary_gland0.91456717
112MP0005058_abnormal_lysosome_morphology0.91099880
113MP0005535_abnormal_body_temperature0.90698285
114MP0002138_abnormal_hepatobiliary_system0.88645337
115MP0003045_fibrosis0.87679072
116MP0005397_hematopoietic_system_phenotyp0.87122902
117MP0001545_abnormal_hematopoietic_system0.87122902
118MP0009765_abnormal_xenobiotic_induced0.86123058
119MP0005165_increased_susceptibility_to0.85564225
120MP0001800_abnormal_humoral_immune0.85461345
121MP0003866_abnormal_defecation0.84351939
122MP0003787_abnormal_imprinting0.82957741
123MP0000955_abnormal_spinal_cord0.82445731
124MP0003690_abnormal_glial_cell0.82386752
125MP0002166_altered_tumor_susceptibility0.81294204
126MP0006276_abnormal_autonomic_nervous0.80305978
127MP0003329_amyloid_beta_deposits0.79871137
128MP0004808_abnormal_hematopoietic_stem0.78210402
129MP0005387_immune_system_phenotype0.78171576
130MP0001790_abnormal_immune_system0.78171576
131MP0001502_abnormal_circadian_rhythm0.77309978
132MP0004885_abnormal_endolymph0.76448884
133MP0003806_abnormal_nucleotide_metabolis0.75547703
134MP0002882_abnormal_neuron_morphology0.75523003
135MP0000604_amyloidosis0.72676055
136MP0002006_tumorigenesis0.72557134
137MP0000685_abnormal_immune_system0.72028295
138MP0002398_abnormal_bone_marrow0.71990288
139MP0003950_abnormal_plasma_membrane0.71804570
140MP0000920_abnormal_myelination0.69472734
141MP0002876_abnormal_thyroid_physiology0.69031707
142MP0009840_abnormal_foam_cell0.67629610
143MP0004130_abnormal_muscle_cell0.66938686
144MP0001663_abnormal_digestive_system0.66280253
145MP0009333_abnormal_splenocyte_physiolog0.66237087
146MP0005595_abnormal_vascular_smooth0.65316534
147MP0000716_abnormal_immune_system0.65022116
148MP0005084_abnormal_gallbladder_morpholo0.64522035
149MP0000778_abnormal_nervous_system0.64072175
150MP0002090_abnormal_vision0.64014645
151MP0001177_atelectasis0.61779478
152MP0002229_neurodegeneration0.61684049
153MP0000230_abnormal_systemic_arterial0.61044796
154MP0003453_abnormal_keratinocyte_physiol0.59653413
155MP0005647_abnormal_sex_gland0.57870230
156MP0000703_abnormal_thymus_morphology0.57689742

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.90603849
2Myokymia (HP:0002411)6.15206762
3Visual hallucinations (HP:0002367)4.72259223
4Focal seizures (HP:0007359)4.64092817
5Papilledema (HP:0001085)4.51966103
6Recurrent abscess formation (HP:0002722)4.25320688
7Abnormality of liposaccharide metabolism (HP:0010968)4.24440437
8Febrile seizures (HP:0002373)4.03215993
9Recurrent bacterial skin infections (HP:0005406)3.95880798
10Spontaneous hematomas (HP:0007420)3.66986513
11Epileptic encephalopathy (HP:0200134)3.55934285
12Poor eye contact (HP:0000817)3.50512319
13Abnormality of the vasculature of the conjunctiva (HP:0008054)3.46797584
14Annular pancreas (HP:0001734)3.45245632
15Action tremor (HP:0002345)3.41072500
16Gaze-evoked nystagmus (HP:0000640)3.39877460
17Autoimmune thrombocytopenia (HP:0001973)3.33572134
18Progressive cerebellar ataxia (HP:0002073)3.30983183
19Broad-based gait (HP:0002136)3.26643748
20Progressive inability to walk (HP:0002505)3.18900587
21Atonic seizures (HP:0010819)3.18816866
22Increased cerebral lipofuscin (HP:0011813)3.17198623
23Eczematoid dermatitis (HP:0000976)3.12413777
24Generalized tonic-clonic seizures (HP:0002069)3.07430425
25Conjunctival telangiectasia (HP:0000524)3.05419938
26Gingival bleeding (HP:0000225)3.04310117
27Increased neuronal autofluorescent lipopigment (HP:0002074)3.03491073
28Keratoconjunctivitis sicca (HP:0001097)3.02747710
29Absence seizures (HP:0002121)3.02230702
30Abnormal social behavior (HP:0012433)2.92559684
31Impaired social interactions (HP:0000735)2.92559684
32Menorrhagia (HP:0000132)2.90860813
33Mutism (HP:0002300)2.90267128
34Abnormal platelet volume (HP:0011876)2.87999500
35Supranuclear gaze palsy (HP:0000605)2.87524219
36Stereotypic behavior (HP:0000733)2.85930771
37Disinhibition (HP:0000734)2.85567805
38Dysostosis multiplex (HP:0000943)2.85057872
39Dialeptic seizures (HP:0011146)2.84400683
40Myositis (HP:0100614)2.83487833
41Postural instability (HP:0002172)2.82241802
42Arterial thrombosis (HP:0004420)2.81696860
43Hematochezia (HP:0002573)2.80887950
44Hemoptysis (HP:0002105)2.79460394
45Autoimmune hemolytic anemia (HP:0001890)2.79139112
46Increased mean platelet volume (HP:0011877)2.78762776
47Keratoconjunctivitis (HP:0001096)2.76866127
48Mediastinal lymphadenopathy (HP:0100721)2.76853787
49Recurrent viral infections (HP:0004429)2.76392499
50Impaired smooth pursuit (HP:0007772)2.73966345
51Pulmonary infiltrates (HP:0002113)2.72115676
52Recurrent gram-negative bacterial infections (HP:0005420)2.71748099
53Recurrent cutaneous fungal infections (HP:0011370)2.71260968
54Chronic mucocutaneous candidiasis (HP:0002728)2.71260968
55Purpura (HP:0000979)2.70911062
56Diplopia (HP:0000651)2.69586602
57Abnormality of binocular vision (HP:0011514)2.69586602
58T lymphocytopenia (HP:0005403)2.68872049
59Vasculitis (HP:0002633)2.66380688
60Amyloidosis (HP:0011034)2.66233226
61Encephalitis (HP:0002383)2.65465002
62Abnormality of T cell number (HP:0011839)2.65132862
63Depression (HP:0000716)2.63681901
64Abnormal delayed hypersensitivity skin test (HP:0002963)2.63164885
65Anxiety (HP:0000739)2.59807638
66Chest pain (HP:0100749)2.59163791
67Prolonged bleeding time (HP:0003010)2.58216066
68Elevated erythrocyte sedimentation rate (HP:0003565)2.57201513
69Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.54843321
70Loss of speech (HP:0002371)2.51038293
71Inappropriate behavior (HP:0000719)2.50508722
72Abnormality of ocular smooth pursuit (HP:0000617)2.47140094
73Scanning speech (HP:0002168)2.45567176
74Truncal ataxia (HP:0002078)2.43623930
75Obstructive lung disease (HP:0006536)2.42706949
76Chronic obstructive pulmonary disease (HP:0006510)2.42706949
77Hyperventilation (HP:0002883)2.42691762
78Vertigo (HP:0002321)2.39728085
79Abnormal platelet function (HP:0011869)2.39574773
80Impaired platelet aggregation (HP:0003540)2.39574773
81Bradykinesia (HP:0002067)2.38945689
82Vacuolated lymphocytes (HP:0001922)2.37669751
83Torticollis (HP:0000473)2.37494827
84Spinal canal stenosis (HP:0003416)2.34188476
85Gastrointestinal infarctions (HP:0005244)2.34070781
86Urticaria (HP:0001025)2.31314942
87Resting tremor (HP:0002322)2.31258566
88Gangrene (HP:0100758)2.30214489
89Thrombocytosis (HP:0001894)2.29397169
90Inability to walk (HP:0002540)2.29036978
91Pulmonary embolism (HP:0002204)2.28618353
92Recurrent skin infections (HP:0001581)2.28346215
93Impaired vibration sensation in the lower limbs (HP:0002166)2.27609965
94Urinary bladder sphincter dysfunction (HP:0002839)2.27271607
95Generalized hypopigmentation of hair (HP:0011358)2.27198728
96Abnormal eating behavior (HP:0100738)2.26823927
97Cellulitis (HP:0100658)2.25755595
98Abnormality of macrophages (HP:0004311)2.25329090
99Dysdiadochokinesis (HP:0002075)2.25179608
100Thick nail (HP:0001805)2.24000592
101Myocardial infarction (HP:0001658)2.23229645
102Focal dystonia (HP:0004373)2.22231724
103Colitis (HP:0002583)2.20859869
104Ocular albinism (HP:0001107)2.20560905
105Amaurosis fugax (HP:0100576)2.19526103
106Agnosia (HP:0010524)2.17843088
107Dysmetria (HP:0001310)2.17054570
108Abnormality of B cell number (HP:0010975)2.16171638
109Leukocytosis (HP:0001974)2.15402919
110Abnormality of the periventricular white matter (HP:0002518)2.14154300
111Optic neuritis (HP:0100653)2.13098375
112Retrobulbar optic neuritis (HP:0100654)2.13098375
113Iris hypopigmentation (HP:0007730)2.11335542
114Polycythemia (HP:0001901)2.08728752
115Ankle clonus (HP:0011448)2.06993840
116Inflammation of the large intestine (HP:0002037)2.06813483
117Dysmetric saccades (HP:0000641)2.06118409
118Recurrent fungal infections (HP:0002841)2.05582391
119Mucosal telangiectasiae (HP:0100579)2.05471966
120Episodic fever (HP:0001954)2.04276166
121Craniofacial dystonia (HP:0012179)2.04061131
122Abnormality of the pleura (HP:0002103)2.04059514
123Acute lymphatic leukemia (HP:0006721)2.03510662
124Orchitis (HP:0100796)2.03185445
125Fair hair (HP:0002286)2.02888918
126Stomatitis (HP:0010280)2.02578665
127Intention tremor (HP:0002080)2.01519113
128Apathy (HP:0000741)2.01198261
129Neoplasm of the tracheobronchial system (HP:0100552)2.00950847
130Genetic anticipation (HP:0003743)2.00597790
131Petechiae (HP:0000967)2.00149805
132Limb dystonia (HP:0002451)1.99637707
133Periodontitis (HP:0000704)1.98473318
134Cerebral hemorrhage (HP:0001342)1.98355847
135Memory impairment (HP:0002354)1.98312446
136Diminished motivation (HP:0000745)1.98097847
137Viral hepatitis (HP:0006562)1.96979883
138Abnormality of the prostate (HP:0008775)1.96732682
139Basal ganglia calcification (HP:0002135)1.95739521
140Abnormality of T cells (HP:0002843)1.95410174
141Hepatosplenomegaly (HP:0001433)1.95176163
142Abnormality of mucopolysaccharide metabolism (HP:0011020)1.94935044
143Abnormality of polysaccharide metabolism (HP:0011012)1.94935044
144Abnormality of glycosaminoglycan metabolism (HP:0004371)1.94935044
145Protruding tongue (HP:0010808)1.94604815
146Epistaxis (HP:0000421)1.94412017
147Hemiplegia (HP:0002301)1.93752288
148J-shaped sella turcica (HP:0002680)1.93470041
149Lower limb amyotrophy (HP:0007210)1.92999274
150Nonprogressive disorder (HP:0003680)1.92782314
151Abnormality of saccadic eye movements (HP:0000570)1.91554513
152Fatigue (HP:0012378)1.90827139
153Polyneuropathy (HP:0001271)1.90533886
154Absent frontal sinuses (HP:0002688)1.90211838
155Pointed chin (HP:0000307)1.89853423
156Alveolar cell carcinoma (HP:0006519)1.89672128
157Neurodegeneration (HP:0002180)1.89458634
158Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.89122100
159Hypothermia (HP:0002045)1.89072502
160Ankyloglossia (HP:0010296)1.87170661
161Neuronal loss in central nervous system (HP:0002529)1.86453977
162Gingivitis (HP:0000230)1.86283103
163Palpebral edema (HP:0100540)1.83785349
164Meningitis (HP:0001287)1.82955213
165Abnormality of glycosphingolipid metabolism (HP:0004343)1.81158774
166Abnormality of glycolipid metabolism (HP:0010969)1.81158774

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK44.82602296
2EPHA44.46686802
3NTRK33.92969287
4MAP3K93.19373417
5MAP3K123.00514529
6FES2.70707995
7TAOK32.62041084
8TNIK2.61039937
9CAMKK22.52375610
10MAP3K132.48454167
11TIE12.47876220
12MAP2K72.35474738
13DAPK22.28529460
14IRAK32.27828077
15CAMKK12.19995337
16MAP2K32.08590543
17CSK2.08385127
18PDK22.07605078
19ACVR1B2.06115303
20MINK12.02422231
21KSR22.01918837
22DAPK11.97772136
23TGFBR21.91967097
24KIT1.85959576
25ARAF1.85637919
26MAP3K41.85163532
27FRK1.83994268
28TYK21.68844339
29MATK1.60664723
30INSRR1.49617806
31IKBKB1.47535565
32BMPR21.44398973
33JAK31.43737398
34PIK3CG1.42896056
35NTRK21.39631152
36IRAK21.37864906
37IRAK11.31527286
38IRAK41.30983724
39MAP2K41.28604580
40CDK191.28208216
41ITK1.28147677
42RAF11.27340864
43MAP3K31.26957027
44SIK21.25982398
45TRPM71.25097919
46NTRK11.24234667
47BLK1.23879961
48MARK11.22406272
49SYK1.16493993
50CDK51.10821311
51MAP3K61.07184750
52KSR11.05229175
53GRK51.04287181
54TNK21.02634356
55SGK20.97960769
56CAMK10.97644325
57PRPF4B0.96262001
58LCK0.95371775
59MAPKAPK50.94899230
60PDK10.94602201
61GRK60.94324834
62PLK20.93760052
63CASK0.92951661
64MUSK0.92316156
65TAOK20.90500409
66PAK60.89927931
67OXSR10.88545842
68TAOK10.88123563
69MAP4K10.84452861
70MAP3K140.83247144
71MAP3K10.81143311
72MAP3K110.80055572
73BMPR1B0.80022080
74SIK30.79955568
75MAPK130.79496784
76MAP3K50.77682285
77IKBKE0.77022646
78ADRBK20.76169924
79MAPK120.75148158
80TEC0.74824221
81TGFBR10.73203829
82HCK0.72638514
83SGK30.71692385
84YES10.69968009
85PIM10.69516444
86MAP3K20.69410699
87TXK0.68032887
88FLT30.67791051
89BTK0.67273912
90PTK2B0.67091222
91MARK30.66909231
92FER0.66147079
93RET0.64454344
94FGR0.64261999
95PRKCH0.63820444
96PRKCG0.63713294
97SGK10.63033527
98PDPK10.62326589
99MAPK70.61374673
100CLK10.60992201
101CAMK2A0.60563098
102LYN0.58131158
103JAK10.56340437
104SGK2230.56007154
105SGK4940.56007154
106WNK10.55614306
107CCNB10.55411399
108GRK70.53828692
109FYN0.53637956
110CDK80.52571479
111PINK10.52536753
112ERBB30.52445151
113RPS6KA20.51861665
114RIPK10.51292699
115TBK10.51031572
116ABL10.50381003
117MOS0.50276829
118CAMK40.49463817
119STK110.48889465
120MAP2K60.47901532
121CDK180.45449870
122EIF2AK30.44145563
123SCYL20.42828698
124BMX0.42778760
125NEK60.42141454
126CDK60.41717587
127NEK90.40166816
128CDK150.39907052
129ALK0.39781025
130CSF1R0.39725453
131ZAP700.39687759
132BRSK10.39583280
133DDR20.38901237
134JAK20.38785689
135PDGFRB0.38662532
136EGFR0.38656968
137CAMK2B0.37856288
138CHUK0.37569909
139IGF1R0.35696446
140PRKD30.35571035
141PKN10.35210826
142CDK11A0.34840842
143STK380.34360326
144PRKCD0.33797676
145MAPK40.32078321
146CAMK1G0.31794020
147CDK140.31012455
148ABL20.24812028

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047403.02826201
2Nicotine addiction_Homo sapiens_hsa050332.94523726
3Allograft rejection_Homo sapiens_hsa053302.73352412
4Synaptic vesicle cycle_Homo sapiens_hsa047212.66656779
5Staphylococcus aureus infection_Homo sapiens_hsa051502.62413144
6Graft-versus-host disease_Homo sapiens_hsa053322.56682180
7Morphine addiction_Homo sapiens_hsa050322.52591267
8Circadian entrainment_Homo sapiens_hsa047132.45345563
9Long-term potentiation_Homo sapiens_hsa047202.42886481
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.36680971
11Autoimmune thyroid disease_Homo sapiens_hsa053202.32602621
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.30289373
13Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.21261679
14Glutamatergic synapse_Homo sapiens_hsa047242.20463004
15Amphetamine addiction_Homo sapiens_hsa050312.19472338
16GABAergic synapse_Homo sapiens_hsa047272.14671196
17Malaria_Homo sapiens_hsa051442.09930084
18Dopaminergic synapse_Homo sapiens_hsa047281.92085760
19Salivary secretion_Homo sapiens_hsa049701.91560473
20Cholinergic synapse_Homo sapiens_hsa047251.85678010
21Cocaine addiction_Homo sapiens_hsa050301.72186469
22Legionellosis_Homo sapiens_hsa051341.72011230
23NF-kappa B signaling pathway_Homo sapiens_hsa040641.68261579
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.66568335
25Toxoplasmosis_Homo sapiens_hsa051451.65305769
26Renin secretion_Homo sapiens_hsa049241.64560237
27Taste transduction_Homo sapiens_hsa047421.61239166
28Calcium signaling pathway_Homo sapiens_hsa040201.60791831
29Serotonergic synapse_Homo sapiens_hsa047261.58950220
30Gastric acid secretion_Homo sapiens_hsa049711.53183667
31Long-term depression_Homo sapiens_hsa047301.51851249
32Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.46490395
33Oxytocin signaling pathway_Homo sapiens_hsa049211.45934331
34Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.44555429
35Antigen processing and presentation_Homo sapiens_hsa046121.37777882
36Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.37007446
37Viral myocarditis_Homo sapiens_hsa054161.34803770
38Collecting duct acid secretion_Homo sapiens_hsa049661.34468228
39GnRH signaling pathway_Homo sapiens_hsa049121.31834815
40Phosphatidylinositol signaling system_Homo sapiens_hsa040701.30893207
41Glycosaminoglycan degradation_Homo sapiens_hsa005311.29771082
42Other glycan degradation_Homo sapiens_hsa005111.29494603
43Insulin secretion_Homo sapiens_hsa049111.26871173
44cAMP signaling pathway_Homo sapiens_hsa040241.22979922
45Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.21407012
46Leishmaniasis_Homo sapiens_hsa051401.20793957
47Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.15391368
48Osteoclast differentiation_Homo sapiens_hsa043801.13522482
49Measles_Homo sapiens_hsa051621.12320067
50Gap junction_Homo sapiens_hsa045401.11767072
51Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.10713713
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.10518979
53Platelet activation_Homo sapiens_hsa046111.10280926
54Jak-STAT signaling pathway_Homo sapiens_hsa046301.10123755
55B cell receptor signaling pathway_Homo sapiens_hsa046621.08905390
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.08049227
57Neurotrophin signaling pathway_Homo sapiens_hsa047221.06965502
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.05785756
59Glioma_Homo sapiens_hsa052141.05013348
60Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.04650044
61Chemokine signaling pathway_Homo sapiens_hsa040621.04308958
62Type II diabetes mellitus_Homo sapiens_hsa049301.02270115
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.01548432
64Herpes simplex infection_Homo sapiens_hsa051681.01069566
65African trypanosomiasis_Homo sapiens_hsa051430.99372962
66Tuberculosis_Homo sapiens_hsa051520.97837921
67Estrogen signaling pathway_Homo sapiens_hsa049150.93010054
68Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.92898079
69Phospholipase D signaling pathway_Homo sapiens_hsa040720.92261682
70Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.91150591
71Type I diabetes mellitus_Homo sapiens_hsa049400.90062833
72Systemic lupus erythematosus_Homo sapiens_hsa053220.88610854
73Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.87617725
74Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.87200456
75Rheumatoid arthritis_Homo sapiens_hsa053230.86983303
76Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.85075831
77Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.84054062
78Sphingolipid signaling pathway_Homo sapiens_hsa040710.83748525
79Toll-like receptor signaling pathway_Homo sapiens_hsa046200.80896048
80Non-small cell lung cancer_Homo sapiens_hsa052230.79836934
81Asthma_Homo sapiens_hsa053100.79781957
82SNARE interactions in vesicular transport_Homo sapiens_hsa041300.77337693
83Acute myeloid leukemia_Homo sapiens_hsa052210.76786153
84Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76094714
85Pertussis_Homo sapiens_hsa051330.76063493
86Dorso-ventral axis formation_Homo sapiens_hsa043200.76011341
87Primary immunodeficiency_Homo sapiens_hsa053400.75642129
88cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75621212
89ErbB signaling pathway_Homo sapiens_hsa040120.75089272
90Salmonella infection_Homo sapiens_hsa051320.74804239
91Amoebiasis_Homo sapiens_hsa051460.74152392
92Pancreatic cancer_Homo sapiens_hsa052120.73822135
93Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.73322446
94VEGF signaling pathway_Homo sapiens_hsa043700.73134290
95Inositol phosphate metabolism_Homo sapiens_hsa005620.72018084
96Vascular smooth muscle contraction_Homo sapiens_hsa042700.70104592
97Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.68480682
98MAPK signaling pathway_Homo sapiens_hsa040100.68308306
99Apoptosis_Homo sapiens_hsa042100.68034417
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.67721405
101RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.67527461
102Phagosome_Homo sapiens_hsa041450.67299312
103Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.67122377
104NOD-like receptor signaling pathway_Homo sapiens_hsa046210.65185841
105Rap1 signaling pathway_Homo sapiens_hsa040150.65135377
106Hepatitis C_Homo sapiens_hsa051600.64848862
107Pancreatic secretion_Homo sapiens_hsa049720.64337470
108Vibrio cholerae infection_Homo sapiens_hsa051100.62381141
109Choline metabolism in cancer_Homo sapiens_hsa052310.62321273
110Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60433626
111Oocyte meiosis_Homo sapiens_hsa041140.59259127
112Melanogenesis_Homo sapiens_hsa049160.58458019
113Transcriptional misregulation in cancer_Homo sapiens_hsa052020.57481302
114TNF signaling pathway_Homo sapiens_hsa046680.55977126
115Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.54705925
116Thyroid hormone synthesis_Homo sapiens_hsa049180.54407831
117Ras signaling pathway_Homo sapiens_hsa040140.53347795
118Chronic myeloid leukemia_Homo sapiens_hsa052200.52908800
119Lysosome_Homo sapiens_hsa041420.52463439
120FoxO signaling pathway_Homo sapiens_hsa040680.51585434
121HIF-1 signaling pathway_Homo sapiens_hsa040660.51202549
122Nitrogen metabolism_Homo sapiens_hsa009100.49991517
123Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49288161
124Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47022528
125Shigellosis_Homo sapiens_hsa051310.46153741
126Prolactin signaling pathway_Homo sapiens_hsa049170.45582646
127Influenza A_Homo sapiens_hsa051640.44693401
128Thyroid hormone signaling pathway_Homo sapiens_hsa049190.44500001
129Adipocytokine signaling pathway_Homo sapiens_hsa049200.43464952
130Endocytosis_Homo sapiens_hsa041440.42848694
131Alcoholism_Homo sapiens_hsa050340.41307938
132Bladder cancer_Homo sapiens_hsa052190.39673938
133Hematopoietic cell lineage_Homo sapiens_hsa046400.39556366
134T cell receptor signaling pathway_Homo sapiens_hsa046600.38788717
135Hepatitis B_Homo sapiens_hsa051610.38183824
136Renal cell carcinoma_Homo sapiens_hsa052110.35978600
137AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35428759
138Sphingolipid metabolism_Homo sapiens_hsa006000.34748350
139Complement and coagulation cascades_Homo sapiens_hsa046100.34009967
140mTOR signaling pathway_Homo sapiens_hsa041500.30692621
141Epstein-Barr virus infection_Homo sapiens_hsa051690.30118096
142Viral carcinogenesis_Homo sapiens_hsa052030.29955165

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