MCTS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.35731910
2energy coupled proton transport, down electrochemical gradient (GO:0015985)5.79319555
3ATP synthesis coupled proton transport (GO:0015986)5.79319555
4mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.52039003
5ribosomal small subunit assembly (GO:0000028)5.02169022
6respiratory electron transport chain (GO:0022904)5.01011161
7mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.96587220
8mitochondrial respiratory chain complex I assembly (GO:0032981)4.96587220
9NADH dehydrogenase complex assembly (GO:0010257)4.96587220
10chaperone-mediated protein transport (GO:0072321)4.95417059
11protein complex biogenesis (GO:0070271)4.94582825
12electron transport chain (GO:0022900)4.89193987
13proteasome assembly (GO:0043248)4.69179416
14mitochondrial respiratory chain complex assembly (GO:0033108)4.56263513
15protein neddylation (GO:0045116)4.46845053
16respiratory chain complex IV assembly (GO:0008535)4.19144673
17DNA deamination (GO:0045006)4.10717498
18cytochrome complex assembly (GO:0017004)3.92208779
19regulation of cellular amino acid metabolic process (GO:0006521)3.90422112
20ribosomal small subunit biogenesis (GO:0042274)3.87135283
21antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.82987093
22establishment of protein localization to mitochondrial membrane (GO:0090151)3.80988256
23regulation of mitochondrial translation (GO:0070129)3.79161615
24establishment of integrated proviral latency (GO:0075713)3.78872053
25negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.78564546
26oxidative phosphorylation (GO:0006119)3.69927071
27cotranslational protein targeting to membrane (GO:0006613)3.66811050
28SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.64464587
29GTP biosynthetic process (GO:0006183)3.64222366
30antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.60678322
31viral transcription (GO:0019083)3.59493340
32protein localization to endoplasmic reticulum (GO:0070972)3.58294110
33protein targeting to ER (GO:0045047)3.58271693
34DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.57891956
35iron-sulfur cluster assembly (GO:0016226)3.57542485
36metallo-sulfur cluster assembly (GO:0031163)3.57542485
37maturation of SSU-rRNA (GO:0030490)3.54846675
38translational termination (GO:0006415)3.54842914
39rRNA modification (GO:0000154)3.54480969
40intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.52105092
41signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.52105092
42protein targeting to mitochondrion (GO:0006626)3.51500536
43termination of RNA polymerase III transcription (GO:0006386)3.47965907
44transcription elongation from RNA polymerase III promoter (GO:0006385)3.47965907
45signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.47158076
46signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.47158076
47signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.47158076
48cullin deneddylation (GO:0010388)3.46943734
49RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.44551566
50tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.44551566
51regulation of ubiquitin-protein transferase activity (GO:0051438)3.43603196
527-methylguanosine mRNA capping (GO:0006370)3.40467800
53protein deneddylation (GO:0000338)3.39700532
54CENP-A containing nucleosome assembly (GO:0034080)3.39599184
552-deoxyribonucleotide biosynthetic process (GO:0009265)3.39512528
56deoxyribose phosphate biosynthetic process (GO:0046385)3.39512528
57RNA capping (GO:0036260)3.39193519
587-methylguanosine RNA capping (GO:0009452)3.39193519
59negative regulation of ligase activity (GO:0051352)3.37700353
60negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.37700353
61positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.37642796
62guanosine-containing compound biosynthetic process (GO:1901070)3.37571245
63establishment of protein localization to mitochondrion (GO:0072655)3.37333678
64establishment of protein localization to endoplasmic reticulum (GO:0072599)3.36993466
65establishment of viral latency (GO:0019043)3.35780606
66regulation of ligase activity (GO:0051340)3.32872681
67inner mitochondrial membrane organization (GO:0007007)3.28439234
68chromatin remodeling at centromere (GO:0031055)3.27571143
69dopamine transport (GO:0015872)3.27124897
70signal transduction involved in DNA integrity checkpoint (GO:0072401)3.26560951
71signal transduction involved in DNA damage checkpoint (GO:0072422)3.26560951
72aerobic respiration (GO:0009060)3.26324458
73regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.21930114
74signal transduction involved in cell cycle checkpoint (GO:0072395)3.21838604
75protein localization to mitochondrion (GO:0070585)3.20557781
76sequestering of actin monomers (GO:0042989)3.20067132
77translation (GO:0006412)3.19075985
78deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.18528760
79regulation of cellular amine metabolic process (GO:0033238)3.12801981
80DNA damage response, detection of DNA damage (GO:0042769)3.09692796
81pseudouridine synthesis (GO:0001522)3.09633579
82hydrogen ion transmembrane transport (GO:1902600)3.09271398
83signal peptide processing (GO:0006465)3.07653589
84ribosomal large subunit biogenesis (GO:0042273)3.07085817
85translational elongation (GO:0006414)3.05813118
86mitochondrial transport (GO:0006839)3.04131376
87DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.03531269
88UTP biosynthetic process (GO:0006228)3.01277027
89antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)3.00437914
90L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.00229236
91protein K11-linked ubiquitination (GO:0070979)2.98795302
92purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.98164403
93cellular component biogenesis (GO:0044085)2.97982559
94negative regulation of protein ubiquitination (GO:0031397)2.97477293
95purine nucleoside triphosphate biosynthetic process (GO:0009145)2.96670351
96regulation of oxidative phosphorylation (GO:0002082)2.96640472
97viral mRNA export from host cell nucleus (GO:0046784)2.96586203
98spliceosomal snRNP assembly (GO:0000387)2.96362849
99* translational initiation (GO:0006413)2.94410011
100maturation of 5.8S rRNA (GO:0000460)2.94024219
101anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.93905293
102positive regulation of cell cycle arrest (GO:0071158)2.90367258
103rRNA methylation (GO:0031167)2.87680023
104nucleoside triphosphate biosynthetic process (GO:0009142)2.86767262
105cellular protein complex disassembly (GO:0043624)2.85820176
106resolution of meiotic recombination intermediates (GO:0000712)2.85363758
107proton transport (GO:0015992)2.84347383
108DNA double-strand break processing (GO:0000729)2.82230888
109mannosylation (GO:0097502)2.81822225
110viral life cycle (GO:0019058)2.81314709
111ATP biosynthetic process (GO:0006754)2.79290700
112positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.76773937
113hydrogen transport (GO:0006818)2.76345085
114nucleobase-containing small molecule interconversion (GO:0015949)2.75397136
115nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.74709742
116pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.74563834
117CTP biosynthetic process (GO:0006241)2.71752725
118CTP metabolic process (GO:0046036)2.71752725
119intracellular protein transmembrane import (GO:0044743)2.70419053
120positive regulation of ligase activity (GO:0051351)2.70055856
121platelet dense granule organization (GO:0060155)2.69514158
122exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.65249029
123ribonucleoside triphosphate biosynthetic process (GO:0009201)2.65030726

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.73019821
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.33092221
3EST1_17652178_ChIP-ChIP_JURKAT_Human3.96105300
4* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.74051811
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.65551172
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.47733291
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.36127683
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.31182793
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.26087224
10* ETS1_20019798_ChIP-Seq_JURKAT_Human3.14345338
11MYC_18555785_ChIP-Seq_MESCs_Mouse2.91690545
12ELF1_17652178_ChIP-ChIP_JURKAT_Human2.90343457
13EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.78161908
14CREB1_15753290_ChIP-ChIP_HEK293T_Human2.71360301
15CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.69120566
16SRF_21415370_ChIP-Seq_HL-1_Mouse2.64827744
17VDR_23849224_ChIP-Seq_CD4+_Human2.56359277
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.51281099
19PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.42443923
20MYC_18358816_ChIP-ChIP_MESCs_Mouse2.35076855
21* ELK1_19687146_ChIP-ChIP_HELA_Human2.34611193
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.31732052
23FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.24455963
24DCP1A_22483619_ChIP-Seq_HELA_Human2.15002961
25FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.13150316
26THAP11_20581084_ChIP-Seq_MESCs_Mouse2.06166630
27HOXB4_20404135_ChIP-ChIP_EML_Mouse2.02704991
28FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.00307409
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.99639135
30IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.97982243
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.95064116
32TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.93565740
33FOXP3_21729870_ChIP-Seq_TREG_Human1.93115225
34YY1_21170310_ChIP-Seq_MESCs_Mouse1.92235670
35MYC_19030024_ChIP-ChIP_MESCs_Mouse1.87170074
36TAF15_26573619_Chip-Seq_HEK293_Human1.85788083
37* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.76241130
38IRF8_21731497_ChIP-ChIP_J774_Mouse1.69819627
39GABP_19822575_ChIP-Seq_HepG2_Human1.62320849
40CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.57670715
41TTF2_22483619_ChIP-Seq_HELA_Human1.56352165
42ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.56002716
43IRF1_19129219_ChIP-ChIP_H3396_Human1.52012399
44* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.50565610
45ZNF274_21170338_ChIP-Seq_K562_Hela1.48891325
46MYC_19079543_ChIP-ChIP_MESCs_Mouse1.47012834
47TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.44074703
48XRN2_22483619_ChIP-Seq_HELA_Human1.43986842
49PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.43677857
50RBPJ_22232070_ChIP-Seq_NCS_Mouse1.43573238
51POU3F2_20337985_ChIP-ChIP_501MEL_Human1.41905433
52ELK1_22589737_ChIP-Seq_MCF10A_Human1.41159144
53NOTCH1_21737748_ChIP-Seq_TLL_Human1.41040745
54SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.38686759
55IRF8_22096565_ChIP-ChIP_GC-B_Human1.35400309
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33072369
57MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.32794769
58MYC_18940864_ChIP-ChIP_HL60_Human1.32254639
59MYCN_18555785_ChIP-Seq_MESCs_Mouse1.31372962
60MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.29469076
61POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.29244232
62FUS_26573619_Chip-Seq_HEK293_Human1.28406853
63YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26417700
64FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.25597550
65GATA1_22025678_ChIP-Seq_K562_Human1.25410847
66VDR_22108803_ChIP-Seq_LS180_Human1.23501180
67E2F7_22180533_ChIP-Seq_HELA_Human1.22145387
68FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.21292645
69FLI1_27457419_Chip-Seq_LIVER_Mouse1.20538889
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19192808
71CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.18611911
72IGF1R_20145208_ChIP-Seq_DFB_Human1.17655844
73PADI4_21655091_ChIP-ChIP_MCF-7_Human1.15908107
74LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.14049210
75GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12829893
76NELFA_20434984_ChIP-Seq_ESCs_Mouse1.11459954
77ZFX_18555785_ChIP-Seq_MESCs_Mouse1.10867931
78HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.10766647
79GBX2_23144817_ChIP-Seq_PC3_Human1.09637459
80EZH2_22144423_ChIP-Seq_EOC_Human1.08955463
81* SPI1_23547873_ChIP-Seq_NB4_Human1.08167047
82EWS_26573619_Chip-Seq_HEK293_Human1.06858110
83ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.05802803
84GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.05102468
85* KDM5A_27292631_Chip-Seq_BREAST_Human1.03141440
86MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.02929216
87E2F1_21310950_ChIP-Seq_MCF-7_Human1.02360656
88FOXM1_23109430_ChIP-Seq_U2OS_Human1.02309884
89E2F4_17652178_ChIP-ChIP_JURKAT_Human1.02278594
90P300_19829295_ChIP-Seq_ESCs_Human1.02220567
91CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.99520620
92DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96954642
93E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.96582708
94STAT4_19710469_ChIP-ChIP_TH1__Mouse0.95890371
95* NANOG_16153702_ChIP-ChIP_HESCs_Human0.95041090
96AR_21909140_ChIP-Seq_LNCAP_Human0.94042961
97PCGF2_27294783_Chip-Seq_ESCs_Mouse0.93331084
98CTBP1_25329375_ChIP-Seq_LNCAP_Human0.93203028
99POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.92043975
100* NANOG_18555785_ChIP-Seq_MESCs_Mouse0.91269598
101NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.91019832
102SOX17_20123909_ChIP-Seq_XEN_Mouse0.90177359
103RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.89308398
104CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.88830529
105CTCF_18555785_ChIP-Seq_MESCs_Mouse0.88152085
106MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.87864143
107BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.87750781
108PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.87004364
109ELF5_23300383_ChIP-Seq_T47D_Human0.86320926
110ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.85412816
111KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.84677279
112PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.84250643
113BMI1_23680149_ChIP-Seq_NPCS_Mouse0.83355482
114CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.82311924
115REST_19997604_ChIP-ChIP_NEURONS_Mouse0.80973159
116EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.79171986
117HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.79143413
118* SOX2_16153702_ChIP-ChIP_HESCs_Human0.79124715
119CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.78859355
120POU5F1_16153702_ChIP-ChIP_HESCs_Human0.77542603
121CTBP2_25329375_ChIP-Seq_LNCAP_Human0.77406096
122SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.77405356
123HTT_18923047_ChIP-ChIP_STHdh_Human0.77351565
124RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.76658182
125JUN_21703547_ChIP-Seq_K562_Human0.76649806
126TP53_22573176_ChIP-Seq_HFKS_Human0.76141254
127FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75852291
128CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.75216014

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.00612945
2MP0009379_abnormal_foot_pigmentation3.66261146
3MP0010094_abnormal_chromosome_stability2.87039437
4MP0006292_abnormal_olfactory_placode2.64693043
5MP0001529_abnormal_vocalization2.49553825
6MP0006276_abnormal_autonomic_nervous2.44773523
7MP0009697_abnormal_copulation2.40097809
8MP0001835_abnormal_antigen_presentation2.35761476
9MP0005671_abnormal_response_to2.34955877
10MP0002736_abnormal_nociception_after2.31632592
11MP0006072_abnormal_retinal_apoptosis2.28455020
12MP0001905_abnormal_dopamine_level2.20594683
13MP0003077_abnormal_cell_cycle2.19011713
14MP0001188_hyperpigmentation2.18596456
15MP0008932_abnormal_embryonic_tissue2.16466887
16MP0001968_abnormal_touch/_nociception2.15483493
17MP0006036_abnormal_mitochondrial_physio2.10326254
18MP0008007_abnormal_cellular_replicative2.07970092
19MP0001986_abnormal_taste_sensitivity2.02922917
20MP0009785_altered_susceptibility_to1.97036225
21MP0002938_white_spotting1.94844521
22MP0001501_abnormal_sleep_pattern1.94739337
23MP0002638_abnormal_pupillary_reflex1.93406636
24MP0002876_abnormal_thyroid_physiology1.91109921
25MP0003724_increased_susceptibility_to1.87561940
26MP0002102_abnormal_ear_morphology1.86654941
27MP0002272_abnormal_nervous_system1.84853493
28MP0008789_abnormal_olfactory_epithelium1.84656564
29MP0009745_abnormal_behavioral_response1.83755531
30MP0002148_abnormal_hypersensitivity_rea1.82768158
31MP0002735_abnormal_chemical_nociception1.82375382
32MP0003111_abnormal_nucleus_morphology1.79978631
33MP0005075_abnormal_melanosome_morpholog1.78264273
34MP0008995_early_reproductive_senescence1.77709135
35MP0002837_dystrophic_cardiac_calcinosis1.74231455
36MP0006035_abnormal_mitochondrial_morpho1.72175385
37MP0004142_abnormal_muscle_tone1.71632718
38MP0002064_seizures1.70846029
39MP0002163_abnormal_gland_morphology1.70790841
40MP0003635_abnormal_synaptic_transmissio1.68125530
41MP0003186_abnormal_redox_activity1.67952583
42MP0004147_increased_porphyrin_level1.59012792
43MP0005084_abnormal_gallbladder_morpholo1.58252933
44MP0003315_abnormal_perineum_morphology1.55696298
45MP0009046_muscle_twitch1.54869963
46MP0005379_endocrine/exocrine_gland_phen1.53932251
47MP0000358_abnormal_cell_content/1.48156026
48MP0010386_abnormal_urinary_bladder1.47653868
49MP0002734_abnormal_mechanical_nocicepti1.45820313
50MP0003011_delayed_dark_adaptation1.44129845
51MP0002572_abnormal_emotion/affect_behav1.41498373
52MP0005174_abnormal_tail_pigmentation1.40344221
53MP0001764_abnormal_homeostasis1.39597669
54MP0005367_renal/urinary_system_phenotyp1.36881995
55MP0000516_abnormal_urinary_system1.36881995
56MP0005408_hypopigmentation1.36387384
57MP0002063_abnormal_learning/memory/cond1.35403567
58MP0008877_abnormal_DNA_methylation1.34671281
59MP0000015_abnormal_ear_pigmentation1.32915057
60MP0001984_abnormal_olfaction1.32762882
61MP0005000_abnormal_immune_tolerance1.32536768
62MP0005025_abnormal_response_to1.31476756
63MP0000372_irregular_coat_pigmentation1.31426615
64MP0005253_abnormal_eye_physiology1.29933156
65MP0001970_abnormal_pain_threshold1.27747173
66MP0004859_abnormal_synaptic_plasticity1.27183017
67MP0002210_abnormal_sex_determination1.25837074
68MP0008875_abnormal_xenobiotic_pharmacok1.21957989
69MP0002234_abnormal_pharynx_morphology1.20172645
70MP0004270_analgesia1.19887507
71MP0008260_abnormal_autophagy1.19594531
72MP0002160_abnormal_reproductive_system1.18988350
73MP0005394_taste/olfaction_phenotype1.18033998
74MP0005499_abnormal_olfactory_system1.18033998
75MP0002067_abnormal_sensory_capabilities1.15513563
76MP0003806_abnormal_nucleotide_metabolis1.14952027
77MP0003890_abnormal_embryonic-extraembry1.14291731
78MP0001486_abnormal_startle_reflex1.14115283
79MP0002733_abnormal_thermal_nociception1.11956960
80MP0002419_abnormal_innate_immunity1.11532546
81MP0003121_genomic_imprinting1.11461219
82MP0003656_abnormal_erythrocyte_physiolo1.10632655
83MP0001929_abnormal_gametogenesis1.09678072
84MP0005423_abnormal_somatic_nervous1.08330938
85MP0003693_abnormal_embryo_hatching1.08006444
86MP0000647_abnormal_sebaceous_gland1.08004472
87MP0003950_abnormal_plasma_membrane1.07607925
88MP0010030_abnormal_orbit_morphology1.06906064
89MP0005409_darkened_coat_color1.05316912
90MP0001440_abnormal_grooming_behavior1.05190543
91MP0005551_abnormal_eye_electrophysiolog1.02800132
92MP0002723_abnormal_immune_serum1.02735905
93MP0005332_abnormal_amino_acid1.02630535
94MP0002420_abnormal_adaptive_immunity1.01615432
95MP0001819_abnormal_immune_cell1.00909684
96MP0005464_abnormal_platelet_physiology1.00129334
97MP0008872_abnormal_physiological_respon0.99438996
98MP0009333_abnormal_splenocyte_physiolog0.99291346
99MP0001853_heart_inflammation0.98725611
100MP0002095_abnormal_skin_pigmentation0.98710722
101MP0002396_abnormal_hematopoietic_system0.98317545
102MP0004924_abnormal_behavior0.98179526
103MP0005386_behavior/neurological_phenoty0.98179526
104MP0003879_abnormal_hair_cell0.97971890
105MP0000653_abnormal_sex_gland0.97759334
106MP0001293_anophthalmia0.97230024
107MP0004215_abnormal_myocardial_fiber0.97194673
108MP0001145_abnormal_male_reproductive0.95318885
109MP0004133_heterotaxia0.95085721
110MP0002006_tumorigenesis0.94157699
111MP0008057_abnormal_DNA_replication0.93705893
112MP0005535_abnormal_body_temperature0.93053208
113MP0001800_abnormal_humoral_immune0.91473680
114MP0003718_maternal_effect0.91457183
115MP0008058_abnormal_DNA_repair0.90943694
116MP0005389_reproductive_system_phenotype0.89423229
117MP0000631_abnormal_neuroendocrine_gland0.88955617
118MP0001727_abnormal_embryo_implantation0.88692212
119MP0002452_abnormal_antigen_presenting0.88117648
120MP0003567_abnormal_fetal_cardiomyocyte0.88095532
121MP0000681_abnormal_thyroid_gland0.86920261
122MP0003436_decreased_susceptibility_to0.86555070
123MP0005636_abnormal_mineral_homeostasis0.86061113
124MP0002751_abnormal_autonomic_nervous0.85791278
125MP0004381_abnormal_hair_follicle0.85664299
126MP0005646_abnormal_pituitary_gland0.84649680
127MP0002822_catalepsy0.83591785
128MP0003763_abnormal_thymus_physiology0.83464974
129MP0002398_abnormal_bone_marrow0.83233546
130MP0002282_abnormal_trachea_morphology0.81786236
131MP0002233_abnormal_nose_morphology0.81506668
132MP0003195_calcinosis0.81438872
133MP0002166_altered_tumor_susceptibility0.81295118
134MP0002184_abnormal_innervation0.81203078
135MP0008469_abnormal_protein_level0.81110625
136MP0004957_abnormal_blastocyst_morpholog0.80465384
137MP0005645_abnormal_hypothalamus_physiol0.80142843
138MP0004510_myositis0.79897561
139MP0000716_abnormal_immune_system0.78222901
140MP0005266_abnormal_metabolism0.77791968
141MP0002090_abnormal_vision0.77408168
142MP0005410_abnormal_fertilization0.77279999
143MP0003786_premature_aging0.76487581
144MP0001697_abnormal_embryo_size0.75979980
145MP0000689_abnormal_spleen_morphology0.75931067
146MP0000749_muscle_degeneration0.75915749
147MP0009764_decreased_sensitivity_to0.75332944
148MP0003698_abnormal_male_reproductive0.75038155
149MP0001119_abnormal_female_reproductive0.74621211
150MP0003937_abnormal_limbs/digits/tail_de0.73447349
151MP0001845_abnormal_inflammatory_respons0.71911391
152MP0003123_paternal_imprinting0.70908989
153MP0006082_CNS_inflammation0.70184350
154MP0005395_other_phenotype0.70026638
155MP0002277_abnormal_respiratory_mucosa0.69706117
156MP0000313_abnormal_cell_death0.68913371
157MP0005085_abnormal_gallbladder_physiolo0.68885216
158MP0001919_abnormal_reproductive_system0.67795712
159MP0000427_abnormal_hair_cycle0.65400267

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.05928861
2Abnormal mitochondria in muscle tissue (HP:0008316)5.57846477
3Mitochondrial inheritance (HP:0001427)5.49695440
4Progressive macrocephaly (HP:0004481)4.96876013
5Acute encephalopathy (HP:0006846)4.95370322
6Hepatocellular necrosis (HP:0001404)4.88573766
7Increased CSF lactate (HP:0002490)4.87674196
8Increased hepatocellular lipid droplets (HP:0006565)4.34823274
9Hepatic necrosis (HP:0002605)4.25514701
103-Methylglutaconic aciduria (HP:0003535)4.02363195
11Lipid accumulation in hepatocytes (HP:0006561)3.93207601
12Renal Fanconi syndrome (HP:0001994)3.70683087
13Abnormality of cells of the erythroid lineage (HP:0012130)3.54464785
14Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.50668012
15Cerebral edema (HP:0002181)3.45630574
16Increased serum lactate (HP:0002151)3.44531007
17Abnormal number of erythroid precursors (HP:0012131)3.42604276
18Decreased activity of mitochondrial respiratory chain (HP:0008972)3.41449467
19Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.41449467
20Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.33279255
21Lactic acidosis (HP:0003128)3.32953747
22Increased intramyocellular lipid droplets (HP:0012240)3.30957833
23Type I transferrin isoform profile (HP:0003642)3.28106391
24Increased serum pyruvate (HP:0003542)3.24122642
25Abnormality of glycolysis (HP:0004366)3.24122642
26Exertional dyspnea (HP:0002875)3.14475995
27Exercise intolerance (HP:0003546)3.13700885
28Optic disc pallor (HP:0000543)3.05222433
29Respiratory failure (HP:0002878)3.02826261
30Hypothermia (HP:0002045)2.91819837
31Focal motor seizures (HP:0011153)2.85817947
32Increased muscle lipid content (HP:0009058)2.79846910
33Abnormality of alanine metabolism (HP:0010916)2.78480634
34Hyperalaninemia (HP:0003348)2.78480634
35Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.78480634
36Aplastic anemia (HP:0001915)2.73726092
37Reduced antithrombin III activity (HP:0001976)2.72797227
38Methylmalonic aciduria (HP:0012120)2.70571089
39Leukodystrophy (HP:0002415)2.64788106
40Respiratory difficulties (HP:0002880)2.62601234
41Methylmalonic acidemia (HP:0002912)2.55650994
42Congenital, generalized hypertrichosis (HP:0004540)2.53375034
43Abnormality of the anterior horn cell (HP:0006802)2.50811008
44Degeneration of anterior horn cells (HP:0002398)2.50811008
45Generalized aminoaciduria (HP:0002909)2.48251074
46Abnormal protein glycosylation (HP:0012346)2.48034550
47Abnormal glycosylation (HP:0012345)2.48034550
48Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.48034550
49Abnormal protein N-linked glycosylation (HP:0012347)2.48034550
50Reticulocytopenia (HP:0001896)2.47255761
51CNS demyelination (HP:0007305)2.26348863
52X-linked dominant inheritance (HP:0001423)2.26234693
53Abnormal hair whorl (HP:0010721)2.23701668
54Abnormality of renal resorption (HP:0011038)2.22779391
55Type 2 muscle fiber atrophy (HP:0003554)2.21978983
56Microvesicular hepatic steatosis (HP:0001414)2.21471451
57Molar tooth sign on MRI (HP:0002419)2.18484934
58Abnormality of midbrain morphology (HP:0002418)2.18484934
59IgM deficiency (HP:0002850)2.17595868
60Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.16477465
61Medial flaring of the eyebrow (HP:0010747)2.14196029
62Cerebral hypomyelination (HP:0006808)2.13929049
63Macrocytic anemia (HP:0001972)2.12507032
64Hyperglycinemia (HP:0002154)2.10568431
65Pallor (HP:0000980)2.10103822
66Aplasia/Hypoplasia of the uvula (HP:0010293)2.08838026
67Emotional lability (HP:0000712)2.08599805
68Abnormality of serum amino acid levels (HP:0003112)2.08574766
69Hyperventilation (HP:0002883)2.08052479
70Abnormality of placental membranes (HP:0011409)2.07410365
71Amniotic constriction ring (HP:0009775)2.07410365
72Abnormality of methionine metabolism (HP:0010901)2.07059393
73Dicarboxylic aciduria (HP:0003215)2.04970069
74Abnormality of dicarboxylic acid metabolism (HP:0010995)2.04970069
75Birth length less than 3rd percentile (HP:0003561)2.00308452
76Pancreatic fibrosis (HP:0100732)1.99782910
77Poor suck (HP:0002033)1.97617095
78Abnormality of the preputium (HP:0100587)1.96899952
79Abnormality of the heme biosynthetic pathway (HP:0010472)1.96751186
80Recurrent abscess formation (HP:0002722)1.96145037
81Gait imbalance (HP:0002141)1.94712041
82Elevated erythrocyte sedimentation rate (HP:0003565)1.92953027
83Myokymia (HP:0002411)1.91983289
84Meckel diverticulum (HP:0002245)1.91220546
85Fair hair (HP:0002286)1.91211577
86Lethargy (HP:0001254)1.90976030
87Muscle fiber atrophy (HP:0100295)1.90929830
88Congenital primary aphakia (HP:0007707)1.90680007
89Stenosis of the external auditory canal (HP:0000402)1.89563097
90Nephrogenic diabetes insipidus (HP:0009806)1.87123982
91Renal cortical cysts (HP:0000803)1.86531248
92Abnormality of chromosome stability (HP:0003220)1.85704806
93Delayed CNS myelination (HP:0002188)1.83990826
94Gliosis (HP:0002171)1.83873876
95Thrombocytosis (HP:0001894)1.83533767
96Abnormality of aspartate family amino acid metabolism (HP:0010899)1.83430511
97Aplasia/Hypoplasia of the sacrum (HP:0008517)1.83339555
98Abnormality of the ileum (HP:0001549)1.80674368
99Recurrent bacterial skin infections (HP:0005406)1.79694551
100Delusions (HP:0000746)1.79452967
101Atonic seizures (HP:0010819)1.79250522
102Absence seizures (HP:0002121)1.78968174
103Neuroendocrine neoplasm (HP:0100634)1.78338191
104Pancytopenia (HP:0001876)1.77550022
105Sparse eyelashes (HP:0000653)1.76323235
106Visual hallucinations (HP:0002367)1.76174735
107Hypoplastic pelvis (HP:0008839)1.74910998
108Postnatal microcephaly (HP:0005484)1.74195951
109True hermaphroditism (HP:0010459)1.72546327
110Colon cancer (HP:0003003)1.72340540
111Adrenal hypoplasia (HP:0000835)1.72335106
112Oral leukoplakia (HP:0002745)1.72002277
113Sclerocornea (HP:0000647)1.70668624
114Aplasia/hypoplasia of the uterus (HP:0008684)1.70616069
115Petechiae (HP:0000967)1.70444169
116CNS hypomyelination (HP:0003429)1.70147171
117Glycosuria (HP:0003076)1.70061671
118Abnormality of urine glucose concentration (HP:0011016)1.70061671
119Abnormality of secondary sexual hair (HP:0009888)1.69213327
120Abnormality of the axillary hair (HP:0100134)1.69213327
121Dialeptic seizures (HP:0011146)1.68918978
122Abnormal lung lobation (HP:0002101)1.66043082
123Pancreatic cysts (HP:0001737)1.65548696
124Hypoplasia of the pons (HP:0012110)1.64607757
125Protruding tongue (HP:0010808)1.64356655
126Small intestinal stenosis (HP:0012848)1.62980439
127Hyperphosphaturia (HP:0003109)1.61138964
128IgG deficiency (HP:0004315)1.60208634
129Blindness (HP:0000618)1.59805196
130Parakeratosis (HP:0001036)1.57744338
131Unsteady gait (HP:0002317)1.56647688
132Abnormality of the columella (HP:0009929)1.56595220
133Epileptic encephalopathy (HP:0200134)1.56337206
134Rough bone trabeculation (HP:0100670)1.55803014
135Irregular epiphyses (HP:0010582)1.54453534
136Generalized hypopigmentation of hair (HP:0011358)1.52730435

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.41221954
2MAP3K123.92132464
3VRK23.68371166
4NME22.92330226
5TNIK2.65069815
6NEK12.58451679
7NME12.39790623
8RIPK42.36749580
9CDK192.35573557
10TRIM282.34931997
11CASK2.30995149
12BUB12.19504177
13MAP2K72.05472317
14MST42.01151197
15ZAK1.94009792
16VRK11.93143076
17NUAK11.77639639
18EIF2AK31.77251649
19EIF2AK11.76043348
20BMPR21.63169843
21PIM21.61823007
22GRK71.60789880
23CDC71.59756878
24WEE11.56485864
25MUSK1.54950371
26MAP4K21.54174030
27BMPR1B1.53424370
28CAMKK21.53063731
29TESK21.52150456
30ARAF1.45526903
31TTK1.43050207
32NTRK31.42550649
33TESK11.42327199
34TXK1.35944657
35TEC1.34145463
36ADRBK21.33954874
37DAPK11.33175233
38BLK1.30145490
39TSSK61.29294016
40MYLK1.28413755
41TAF11.27428976
42CCNB11.26956791
43GRK51.24862552
44PLK21.16715218
45BRSK21.14439137
46PLK11.11284034
47CSNK1A1L1.11156946
48SYK1.09621810
49CSNK1G11.09295684
50MKNK21.07749312
51MAP3K141.03739677
52CDK81.03571559
53PBK1.02331638
54YES11.00338835
55ACVR1B0.99704112
56BCKDK0.97357686
57KIT0.96616421
58SIK30.95862890
59MKNK10.90373724
60FES0.89734335
61EPHA40.89259380
62ABL20.86234818
63IRAK30.84059702
64IRAK40.83579894
65BCR0.82671734
66MINK10.81816762
67AURKB0.80850022
68CHEK20.79605428
69SRPK10.78527318
70OXSR10.77981330
71FRK0.77364118
72TAOK20.74247459
73TLK10.74202349
74ILK0.73970804
75EIF2AK20.73252924
76BRAF0.69283552
77ERBB30.68089524
78PINK10.67194628
79LYN0.64956682
80DYRK30.64428038
81GRK60.63559001
82RAF10.63336255
83GRK10.62347993
84MAP2K40.61646534
85MAPK130.60624751
86INSRR0.60492832
87CAMK2B0.60350308
88MAP4K10.60309332
89PRKCG0.59023922
90PAK40.58267115
91CSNK1G30.57745265
92MAP2K60.57149005
93MAP3K40.56357269
94BTK0.56163631
95PIK3CG0.55303948
96DYRK20.54698130
97RPS6KA40.54638324
98ATR0.54235652
99MAP3K130.53848297
100FLT30.50898347
101MAPKAPK50.50691321
102RPS6KA50.50075416
103KDR0.49101460
104DAPK20.48442034
105BRSK10.48131266
106MAPK40.47852506
107ADRBK10.46555220
108TGFBR10.46150375
109CAMK2A0.45783546
110PRKCI0.45743083
111PAK10.45029025
112IKBKB0.44641337
113PLK30.43951182
114CSNK2A10.43407913
115DAPK30.42488593
116CDK140.41884655
117PDK20.41402546
118MAP3K50.40832842
119PLK40.40025936
120MATK0.39300303
121AKT30.39254657
122CSNK2A20.38311572
123TNK20.38071036
124WNK30.37969367
125CDK180.35608516
126CSNK1A10.35305205
127CSF1R0.35000461
128ATM0.34549964
129SCYL20.33230029
130CSNK1G20.33087487
131PRKCE0.32795618
132PHKG10.32620572
133PHKG20.32620572
134PRKCD0.32014226
135MARK10.31483589
136LIMK10.31387074
137AURKA0.31067611
138PAK30.30642048
139LCK0.30473898

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001905.10621545
2Proteasome_Homo sapiens_hsa030504.92215124
3Ribosome_Homo sapiens_hsa030104.30437095
4Parkinsons disease_Homo sapiens_hsa050124.25817993
5Protein export_Homo sapiens_hsa030603.47446325
6Alzheimers disease_Homo sapiens_hsa050103.23987612
7Huntingtons disease_Homo sapiens_hsa050162.92564951
8RNA polymerase_Homo sapiens_hsa030202.88860256
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.55810065
10Collecting duct acid secretion_Homo sapiens_hsa049662.25686910
11DNA replication_Homo sapiens_hsa030302.02898766
12Pyrimidine metabolism_Homo sapiens_hsa002401.98721050
13Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.77222172
14Nicotine addiction_Homo sapiens_hsa050331.70696209
15Mismatch repair_Homo sapiens_hsa034301.63661973
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.59698421
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.56182119
18Propanoate metabolism_Homo sapiens_hsa006401.50200483
19SNARE interactions in vesicular transport_Homo sapiens_hsa041301.48158877
20Cardiac muscle contraction_Homo sapiens_hsa042601.40761003
21Nucleotide excision repair_Homo sapiens_hsa034201.39200958
22Vibrio cholerae infection_Homo sapiens_hsa051101.38837074
23Homologous recombination_Homo sapiens_hsa034401.31673171
24Purine metabolism_Homo sapiens_hsa002301.27691944
25Spliceosome_Homo sapiens_hsa030401.26872778
26Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.21598697
27Rheumatoid arthritis_Homo sapiens_hsa053231.18484036
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.17045316
29Base excision repair_Homo sapiens_hsa034101.13933541
30Synaptic vesicle cycle_Homo sapiens_hsa047211.12446292
31One carbon pool by folate_Homo sapiens_hsa006701.08822090
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.05319991
33Folate biosynthesis_Homo sapiens_hsa007901.05298003
34Steroid biosynthesis_Homo sapiens_hsa001001.03559585
35Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.02975145
36Regulation of autophagy_Homo sapiens_hsa041401.02862854
37Graft-versus-host disease_Homo sapiens_hsa053321.01194671
38Sulfur relay system_Homo sapiens_hsa041220.99778386
39Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.97970688
40Phagosome_Homo sapiens_hsa041450.93767915
41Type I diabetes mellitus_Homo sapiens_hsa049400.90248266
422-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.90137716
43Allograft rejection_Homo sapiens_hsa053300.88452031
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88244654
45Cell cycle_Homo sapiens_hsa041100.87874485
46Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.85771795
47Fatty acid elongation_Homo sapiens_hsa000620.84566863
48Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.84033826
49RNA degradation_Homo sapiens_hsa030180.83713496
50Basal transcription factors_Homo sapiens_hsa030220.82988416
51Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.82746575
52Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.82481181
53Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82260218
54Butanoate metabolism_Homo sapiens_hsa006500.80612790
55N-Glycan biosynthesis_Homo sapiens_hsa005100.77688565
56Metabolic pathways_Homo sapiens_hsa011000.76974234
57Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.70864458
58RNA transport_Homo sapiens_hsa030130.69825616
59Serotonergic synapse_Homo sapiens_hsa047260.69577872
60Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.67561767
61Primary immunodeficiency_Homo sapiens_hsa053400.66956384
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64692210
63Legionellosis_Homo sapiens_hsa051340.60861268
64Taste transduction_Homo sapiens_hsa047420.59938252
65Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58937728
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.58507182
67Biosynthesis of amino acids_Homo sapiens_hsa012300.56371209
68Pentose and glucuronate interconversions_Homo sapiens_hsa000400.55770339
69Morphine addiction_Homo sapiens_hsa050320.54859663
70GABAergic synapse_Homo sapiens_hsa047270.54687358
71Oocyte meiosis_Homo sapiens_hsa041140.54070080
72Sulfur metabolism_Homo sapiens_hsa009200.52350412
73Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.52081610
74Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51367665
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51276742
76Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50875371
77Tryptophan metabolism_Homo sapiens_hsa003800.50104574
78Hematopoietic cell lineage_Homo sapiens_hsa046400.47983408
79Epstein-Barr virus infection_Homo sapiens_hsa051690.47879300
80Asthma_Homo sapiens_hsa053100.47876616
81Peroxisome_Homo sapiens_hsa041460.47290046
82Primary bile acid biosynthesis_Homo sapiens_hsa001200.47278760
83Phototransduction_Homo sapiens_hsa047440.45925756
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.45223196
85Chemical carcinogenesis_Homo sapiens_hsa052040.45050828
86Cysteine and methionine metabolism_Homo sapiens_hsa002700.45037262
87Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44983490
88Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.44983064
89Fanconi anemia pathway_Homo sapiens_hsa034600.44529475
90Glutathione metabolism_Homo sapiens_hsa004800.44146658
91African trypanosomiasis_Homo sapiens_hsa051430.43491935
92p53 signaling pathway_Homo sapiens_hsa041150.43155130
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.41009391
94Olfactory transduction_Homo sapiens_hsa047400.40992177
95Amphetamine addiction_Homo sapiens_hsa050310.40583136
96Pertussis_Homo sapiens_hsa051330.40052915
97beta-Alanine metabolism_Homo sapiens_hsa004100.36000934
98Autoimmune thyroid disease_Homo sapiens_hsa053200.35159218
99Selenocompound metabolism_Homo sapiens_hsa004500.34847682
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.34628186
101Long-term potentiation_Homo sapiens_hsa047200.34592783
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.34547575
103Drug metabolism - other enzymes_Homo sapiens_hsa009830.33880504
104Pentose phosphate pathway_Homo sapiens_hsa000300.33003764
105Intestinal immune network for IgA production_Homo sapiens_hsa046720.32814652
106Pyruvate metabolism_Homo sapiens_hsa006200.32306693
107Non-homologous end-joining_Homo sapiens_hsa034500.32005258
108Arachidonic acid metabolism_Homo sapiens_hsa005900.31444337
109Caffeine metabolism_Homo sapiens_hsa002320.30241264
110Glutamatergic synapse_Homo sapiens_hsa047240.30144821
111Calcium signaling pathway_Homo sapiens_hsa040200.29916583
112Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.29665418
113Systemic lupus erythematosus_Homo sapiens_hsa053220.29571546
114Retinol metabolism_Homo sapiens_hsa008300.29371836
115Circadian entrainment_Homo sapiens_hsa047130.28594837
116Fatty acid metabolism_Homo sapiens_hsa012120.27557158
117RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.27383614
118Tyrosine metabolism_Homo sapiens_hsa003500.27366259
119Arginine and proline metabolism_Homo sapiens_hsa003300.24924234
120Fatty acid degradation_Homo sapiens_hsa000710.24330106
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24214148
122Antigen processing and presentation_Homo sapiens_hsa046120.24193559
123mRNA surveillance pathway_Homo sapiens_hsa030150.23770690
124NOD-like receptor signaling pathway_Homo sapiens_hsa046210.23170431
125Dopaminergic synapse_Homo sapiens_hsa047280.22110068
126Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.21911308
127Alcoholism_Homo sapiens_hsa050340.21711050
128Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.19461406
129Phenylalanine metabolism_Homo sapiens_hsa003600.18515760
130Tuberculosis_Homo sapiens_hsa051520.18193778
131Fructose and mannose metabolism_Homo sapiens_hsa000510.17901016
132Nitrogen metabolism_Homo sapiens_hsa009100.17817773
133Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.15757564
134Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.14856232
135Histidine metabolism_Homo sapiens_hsa003400.14814009
136Carbon metabolism_Homo sapiens_hsa012000.14453511
137Galactose metabolism_Homo sapiens_hsa000520.12907858
138Leishmaniasis_Homo sapiens_hsa051400.12403337
139Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.11959411
140Shigellosis_Homo sapiens_hsa051310.11612685

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