

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA unwinding involved in DNA replication (GO:0006268) | 4.54633754 |
| 2 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.49595214 |
| 3 | DNA strand elongation (GO:0022616) | 4.35870600 |
| 4 | nuclear pore complex assembly (GO:0051292) | 4.34708814 |
| 5 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.24892064 |
| 6 | DNA topological change (GO:0006265) | 4.18467535 |
| 7 | establishment of integrated proviral latency (GO:0075713) | 4.11054252 |
| 8 | nuclear pore organization (GO:0006999) | 4.07013781 |
| 9 | mitotic sister chromatid segregation (GO:0000070) | 4.05787212 |
| 10 | CENP-A containing nucleosome assembly (GO:0034080) | 3.93847993 |
| 11 | sister chromatid segregation (GO:0000819) | 3.88977281 |
| 12 | chromatin remodeling at centromere (GO:0031055) | 3.81473365 |
| 13 | DNA ligation (GO:0006266) | 3.80359145 |
| 14 | mitotic nuclear envelope disassembly (GO:0007077) | 3.61731638 |
| 15 | telomere maintenance via recombination (GO:0000722) | 3.61617623 |
| 16 | mitotic recombination (GO:0006312) | 3.60566866 |
| 17 | protein localization to chromosome, centromeric region (GO:0071459) | 3.55022886 |
| 18 | regulation of mitochondrial translation (GO:0070129) | 3.49918189 |
| 19 | termination of RNA polymerase II transcription (GO:0006369) | 3.46205901 |
| 20 | proteasome assembly (GO:0043248) | 3.45178567 |
| 21 | nuclear envelope reassembly (GO:0031468) | 3.42890611 |
| 22 | mitotic nuclear envelope reassembly (GO:0007084) | 3.42890611 |
| 23 | ribosome biogenesis (GO:0042254) | 3.40465430 |
| 24 | mitotic chromosome condensation (GO:0007076) | 3.38680135 |
| 25 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.35028674 |
| 26 | viral mRNA export from host cell nucleus (GO:0046784) | 3.33866015 |
| 27 | mitotic sister chromatid cohesion (GO:0007064) | 3.33204650 |
| 28 | membrane disassembly (GO:0030397) | 3.31342405 |
| 29 | nuclear envelope disassembly (GO:0051081) | 3.31342405 |
| 30 | mitotic metaphase plate congression (GO:0007080) | 3.31064080 |
| 31 | purine nucleobase biosynthetic process (GO:0009113) | 3.30973858 |
| 32 | DNA double-strand break processing (GO:0000729) | 3.28060843 |
| 33 | protein localization to kinetochore (GO:0034501) | 3.28015565 |
| 34 | regulation of centriole replication (GO:0046599) | 3.26253369 |
| 35 | tRNA aminoacylation for protein translation (GO:0006418) | 3.26030135 |
| 36 | kinetochore organization (GO:0051383) | 3.25953336 |
| 37 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.25837348 |
| 38 | DNA replication-independent nucleosome organization (GO:0034724) | 3.25192604 |
| 39 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.25192604 |
| 40 | DNA replication initiation (GO:0006270) | 3.19063863 |
| 41 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.18349038 |
| 42 | histone H2A acetylation (GO:0043968) | 3.17650621 |
| 43 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.17298820 |
| 44 | IMP biosynthetic process (GO:0006188) | 3.16613495 |
| 45 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.16250517 |
| 46 | amino acid activation (GO:0043038) | 3.15930667 |
| 47 | tRNA aminoacylation (GO:0043039) | 3.15930667 |
| 48 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.15855993 |
| 49 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.15855993 |
| 50 | pore complex assembly (GO:0046931) | 3.15841128 |
| 51 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.15752901 |
| 52 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.15752901 |
| 53 | DNA replication checkpoint (GO:0000076) | 3.15662208 |
| 54 | histone exchange (GO:0043486) | 3.13705037 |
| 55 | deoxyribonucleotide biosynthetic process (GO:0009263) | 3.11417469 |
| 56 | ribosome assembly (GO:0042255) | 3.11031540 |
| 57 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.08611901 |
| 58 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.08611901 |
| 59 | mitochondrial RNA metabolic process (GO:0000959) | 3.07746286 |
| 60 | nucleobase biosynthetic process (GO:0046112) | 3.07014034 |
| 61 | telomere maintenance via telomere lengthening (GO:0010833) | 3.06043566 |
| 62 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.05715479 |
| 63 | spindle checkpoint (GO:0031577) | 3.05507984 |
| 64 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.04343971 |
| 65 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.03979180 |
| 66 | regulation of translational termination (GO:0006449) | 3.02367212 |
| 67 | mRNA splicing, via spliceosome (GO:0000398) | 3.01730085 |
| 68 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 3.01730085 |
| 69 | establishment of viral latency (GO:0019043) | 3.01357625 |
| 70 | RNA splicing, via transesterification reactions (GO:0000375) | 3.01334157 |
| 71 | spliceosomal snRNP assembly (GO:0000387) | 2.99820892 |
| 72 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.97676838 |
| 73 | DNA damage response, detection of DNA damage (GO:0042769) | 2.97539382 |
| 74 | ATP-dependent chromatin remodeling (GO:0043044) | 2.97172447 |
| 75 | negative regulation of mRNA processing (GO:0050686) | 2.96623156 |
| 76 | regulation of helicase activity (GO:0051095) | 2.96092969 |
| 77 | negative regulation of chromosome segregation (GO:0051985) | 2.95818738 |
| 78 | mitotic spindle checkpoint (GO:0071174) | 2.92882963 |
| 79 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.92845300 |
| 80 | formation of translation preinitiation complex (GO:0001731) | 2.92325001 |
| 81 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.90477269 |
| 82 | base-excision repair (GO:0006284) | 2.89935744 |
| 83 | kinetochore assembly (GO:0051382) | 2.89271246 |
| 84 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.88050451 |
| 85 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.88050451 |
| 86 | negative regulation of sister chromatid segregation (GO:0033046) | 2.88050451 |
| 87 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.88050451 |
| 88 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.88050451 |
| 89 | spindle assembly checkpoint (GO:0071173) | 2.87915827 |
| 90 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.86679395 |
| 91 | mitotic spindle assembly checkpoint (GO:0007094) | 2.86437945 |
| 92 | DNA-templated transcription, termination (GO:0006353) | 2.86398065 |
| 93 | de novo protein folding (GO:0006458) | 2.84138164 |
| 94 | metaphase plate congression (GO:0051310) | 2.84038281 |
| 95 | regulation of sister chromatid cohesion (GO:0007063) | 2.83614372 |
| 96 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.82661444 |
| 97 | non-recombinational repair (GO:0000726) | 2.82661444 |
| 98 | de novo posttranslational protein folding (GO:0051084) | 2.81577018 |
| 99 | L-serine metabolic process (GO:0006563) | 2.80761854 |
| 100 | protein localization to chromosome (GO:0034502) | 2.80697728 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.74213309 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.15587802 |
| 3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.99612683 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.99084996 |
| 5 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.92250593 |
| 6 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.63633113 |
| 7 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.43245589 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.41281864 |
| 9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.29932873 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.23091454 |
| 11 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.10447968 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.98412849 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.91943333 |
| 14 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.74485741 |
| 15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.70976217 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.67628262 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.67169240 |
| 18 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.62852194 |
| 19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.57803519 |
| 20 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.55922062 |
| 21 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.44549173 |
| 22 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.43405013 |
| 23 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.39946081 |
| 24 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.36642457 |
| 25 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.36628909 |
| 26 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.32836547 |
| 27 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.32287180 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.28552927 |
| 29 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.21105563 |
| 30 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.16030102 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.13007441 |
| 32 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.06054605 |
| 33 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.05356728 |
| 34 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 2.02970030 |
| 35 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.02946726 |
| 36 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.99901922 |
| 37 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.99677469 |
| 38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.98227036 |
| 39 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.97306016 |
| 40 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.97035632 |
| 41 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.91891531 |
| 42 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.89657353 |
| 43 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.88261888 |
| 44 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.86330075 |
| 45 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.82554042 |
| 46 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.77501757 |
| 47 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.74785716 |
| 48 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.73839730 |
| 49 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.66611105 |
| 50 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.64809968 |
| 51 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.64285426 |
| 52 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.62892022 |
| 53 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.59727883 |
| 54 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.56313075 |
| 55 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.55636702 |
| 56 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.46490000 |
| 57 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.44270714 |
| 58 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.40299437 |
| 59 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.38697827 |
| 60 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.35663613 |
| 61 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.33590464 |
| 62 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.33110719 |
| 63 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.31909774 |
| 64 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.31670151 |
| 65 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.28152507 |
| 66 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.21061232 |
| 67 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.18698286 |
| 68 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.17636149 |
| 69 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.16644030 |
| 70 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.15944169 |
| 71 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.15448825 |
| 72 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.10810200 |
| 73 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.09142989 |
| 74 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.08128392 |
| 75 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.06889814 |
| 76 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.04195042 |
| 77 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01094283 |
| 78 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99296821 |
| 79 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.98492678 |
| 80 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.97844665 |
| 81 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.95600892 |
| 82 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.92421550 |
| 83 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.91947621 |
| 84 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.91826376 |
| 85 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.90782687 |
| 86 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.90706899 |
| 87 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.89987452 |
| 88 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.89136793 |
| 89 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.88129326 |
| 90 | MYC_22102868_ChIP-Seq_BL_Human | 0.85536400 |
| 91 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.85048045 |
| 92 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.84894142 |
| 93 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.83246486 |
| 94 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.82730078 |
| 95 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.82530757 |
| 96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.80557297 |
| 97 | EWS_26573619_Chip-Seq_HEK293_Human | 0.80202111 |
| 98 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.77930309 |
| 99 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.75674721 |
| 100 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.75620011 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 4.84430997 |
| 2 | MP0003693_abnormal_embryo_hatching | 4.53857849 |
| 3 | MP0003111_abnormal_nucleus_morphology | 4.33539457 |
| 4 | MP0008058_abnormal_DNA_repair | 4.24745161 |
| 5 | MP0008057_abnormal_DNA_replication | 3.75784953 |
| 6 | MP0004957_abnormal_blastocyst_morpholog | 3.57657233 |
| 7 | MP0003077_abnormal_cell_cycle | 3.53563364 |
| 8 | MP0008932_abnormal_embryonic_tissue | 3.13815233 |
| 9 | MP0008007_abnormal_cellular_replicative | 2.64497038 |
| 10 | MP0003221_abnormal_cardiomyocyte_apopto | 2.40541397 |
| 11 | MP0003786_premature_aging | 2.29696781 |
| 12 | MP0002822_catalepsy | 2.20471623 |
| 13 | MP0009697_abnormal_copulation | 2.19973273 |
| 14 | MP0001529_abnormal_vocalization | 2.19291467 |
| 15 | MP0005623_abnormal_meninges_morphology | 2.06069072 |
| 16 | MP0000372_irregular_coat_pigmentation | 2.01954520 |
| 17 | MP0008789_abnormal_olfactory_epithelium | 1.91154613 |
| 18 | MP0001730_embryonic_growth_arrest | 1.85686220 |
| 19 | MP0000350_abnormal_cell_proliferation | 1.78668542 |
| 20 | MP0002234_abnormal_pharynx_morphology | 1.76350274 |
| 21 | MP0002102_abnormal_ear_morphology | 1.74444612 |
| 22 | MP0001697_abnormal_embryo_size | 1.73069478 |
| 23 | MP0005394_taste/olfaction_phenotype | 1.70828830 |
| 24 | MP0005499_abnormal_olfactory_system | 1.70828830 |
| 25 | MP0002396_abnormal_hematopoietic_system | 1.70261599 |
| 26 | MP0008995_early_reproductive_senescence | 1.63370488 |
| 27 | MP0006035_abnormal_mitochondrial_morpho | 1.61310547 |
| 28 | MP0002080_prenatal_lethality | 1.51510743 |
| 29 | MP0005380_embryogenesis_phenotype | 1.50676855 |
| 30 | MP0001672_abnormal_embryogenesis/_devel | 1.50676855 |
| 31 | MP0003718_maternal_effect | 1.50204041 |
| 32 | MP0004197_abnormal_fetal_growth/weight/ | 1.42234335 |
| 33 | MP0000313_abnormal_cell_death | 1.39472632 |
| 34 | MP0006036_abnormal_mitochondrial_physio | 1.38613614 |
| 35 | MP0001293_anophthalmia | 1.38081985 |
| 36 | MP0004233_abnormal_muscle_weight | 1.36709732 |
| 37 | MP0003984_embryonic_growth_retardation | 1.34699870 |
| 38 | MP0000358_abnormal_cell_content/ | 1.32234627 |
| 39 | MP0003315_abnormal_perineum_morphology | 1.29628325 |
| 40 | MP0000490_abnormal_crypts_of | 1.29323014 |
| 41 | MP0002085_abnormal_embryonic_tissue | 1.27703102 |
| 42 | MP0003121_genomic_imprinting | 1.26303831 |
| 43 | MP0002088_abnormal_embryonic_growth/wei | 1.25862559 |
| 44 | MP0003385_abnormal_body_wall | 1.24379018 |
| 45 | MP0008260_abnormal_autophagy | 1.20862987 |
| 46 | MP0000049_abnormal_middle_ear | 1.18842672 |
| 47 | MP0002084_abnormal_developmental_patter | 1.18787466 |
| 48 | MP0002132_abnormal_respiratory_system | 1.18594474 |
| 49 | MP0003122_maternal_imprinting | 1.15506790 |
| 50 | MP0003937_abnormal_limbs/digits/tail_de | 1.14840615 |
| 51 | MP0005501_abnormal_skin_physiology | 1.13727177 |
| 52 | MP0008961_abnormal_basal_metabolism | 1.08807220 |
| 53 | MP0002019_abnormal_tumor_incidence | 1.06054685 |
| 54 | MP0009672_abnormal_birth_weight | 1.04989791 |
| 55 | MP0004147_increased_porphyrin_level | 1.04464080 |
| 56 | MP0006292_abnormal_olfactory_placode | 1.03913414 |
| 57 | MP0001286_abnormal_eye_development | 1.03590234 |
| 58 | MP0005084_abnormal_gallbladder_morpholo | 1.00168935 |
| 59 | MP0002086_abnormal_extraembryonic_tissu | 0.99935148 |
| 60 | MP0000537_abnormal_urethra_morphology | 0.98183717 |
| 61 | MP0005367_renal/urinary_system_phenotyp | 0.95663508 |
| 62 | MP0000516_abnormal_urinary_system | 0.95663508 |
| 63 | MP0003890_abnormal_embryonic-extraembry | 0.95218239 |
| 64 | MP0003567_abnormal_fetal_cardiomyocyte | 0.95046586 |
| 65 | MP0003119_abnormal_digestive_system | 0.88039935 |
| 66 | MP0001661_extended_life_span | 0.86257471 |
| 67 | MP0003755_abnormal_palate_morphology | 0.83976672 |
| 68 | MP0005384_cellular_phenotype | 0.83499785 |
| 69 | MP0006072_abnormal_retinal_apoptosis | 0.82807560 |
| 70 | MP0001188_hyperpigmentation | 0.82382239 |
| 71 | MP0002111_abnormal_tail_morphology | 0.80393966 |
| 72 | MP0000566_synostosis | 0.78004345 |
| 73 | MP0002697_abnormal_eye_size | 0.76384029 |
| 74 | MP0002233_abnormal_nose_morphology | 0.75397042 |
| 75 | MP0001346_abnormal_lacrimal_gland | 0.74757270 |
| 76 | MP0005266_abnormal_metabolism | 0.74425573 |
| 77 | MP0002210_abnormal_sex_determination | 0.73985809 |
| 78 | MP0003861_abnormal_nervous_system | 0.72849889 |
| 79 | MP0009703_decreased_birth_body | 0.72264261 |
| 80 | MP0010030_abnormal_orbit_morphology | 0.72061755 |
| 81 | MP0003115_abnormal_respiratory_system | 0.71668954 |
| 82 | MP0001929_abnormal_gametogenesis | 0.71224481 |
| 83 | MP0002269_muscular_atrophy | 0.69673572 |
| 84 | MP0003935_abnormal_craniofacial_develop | 0.68891203 |
| 85 | MP0002092_abnormal_eye_morphology | 0.68813762 |
| 86 | MP0000579_abnormal_nail_morphology | 0.68052095 |
| 87 | MP0001764_abnormal_homeostasis | 0.67602539 |
| 88 | MP0002751_abnormal_autonomic_nervous | 0.66841022 |
| 89 | MP0001984_abnormal_olfaction | 0.66399389 |
| 90 | MP0000762_abnormal_tongue_morphology | 0.65921461 |
| 91 | MP0003656_abnormal_erythrocyte_physiolo | 0.65918128 |
| 92 | MP0004811_abnormal_neuron_physiology | 0.64923582 |
| 93 | MP0005083_abnormal_biliary_tract | 0.63228426 |
| 94 | MP0003186_abnormal_redox_activity | 0.62248849 |
| 95 | MP0002177_abnormal_outer_ear | 0.61031069 |
| 96 | MP0001145_abnormal_male_reproductive | 0.60913579 |
| 97 | MP0002081_perinatal_lethality | 0.60385112 |
| 98 | MP0002282_abnormal_trachea_morphology | 0.59943410 |
| 99 | MP0005621_abnormal_cell_physiology | 0.59571517 |
| 100 | MP0005187_abnormal_penis_morphology | 0.58044688 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Microvesicular hepatic steatosis (HP:0001414) | 4.43384961 |
| 2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.85118500 |
| 3 | Abnormality of glycolysis (HP:0004366) | 3.66916213 |
| 4 | Increased serum pyruvate (HP:0003542) | 3.55109694 |
| 5 | Chromsome breakage (HP:0040012) | 3.54190441 |
| 6 | Medulloblastoma (HP:0002885) | 3.27421272 |
| 7 | Abnormality of the preputium (HP:0100587) | 3.23155680 |
| 8 | Cortical dysplasia (HP:0002539) | 3.17316157 |
| 9 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.16739467 |
| 10 | Abnormality of chromosome stability (HP:0003220) | 3.10680084 |
| 11 | Meckel diverticulum (HP:0002245) | 3.03727352 |
| 12 | Duodenal stenosis (HP:0100867) | 2.97418359 |
| 13 | Small intestinal stenosis (HP:0012848) | 2.97418359 |
| 14 | Ragged-red muscle fibers (HP:0003200) | 2.93366765 |
| 15 | Cerebral hypomyelination (HP:0006808) | 2.90636473 |
| 16 | Type I transferrin isoform profile (HP:0003642) | 2.87774512 |
| 17 | Abnormal protein glycosylation (HP:0012346) | 2.86323612 |
| 18 | Abnormal glycosylation (HP:0012345) | 2.86323612 |
| 19 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.86323612 |
| 20 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.86323612 |
| 21 | Abnormality of the ileum (HP:0001549) | 2.84456308 |
| 22 | Hepatocellular necrosis (HP:0001404) | 2.73896544 |
| 23 | Retinal dysplasia (HP:0007973) | 2.67565832 |
| 24 | Hepatic necrosis (HP:0002605) | 2.64862462 |
| 25 | Progressive muscle weakness (HP:0003323) | 2.64077876 |
| 26 | Hypoplastic pelvis (HP:0008839) | 2.63185894 |
| 27 | Myelodysplasia (HP:0002863) | 2.57921666 |
| 28 | Increased serum lactate (HP:0002151) | 2.52478463 |
| 29 | Shoulder girdle muscle weakness (HP:0003547) | 2.51904115 |
| 30 | Abnormality of the labia minora (HP:0012880) | 2.49664192 |
| 31 | Multiple enchondromatosis (HP:0005701) | 2.45766255 |
| 32 | Increased hepatocellular lipid droplets (HP:0006565) | 2.40084754 |
| 33 | Abnormality of the duodenum (HP:0002246) | 2.37710798 |
| 34 | Postnatal microcephaly (HP:0005484) | 2.36699766 |
| 35 | Lipid accumulation in hepatocytes (HP:0006561) | 2.33004042 |
| 36 | Increased CSF lactate (HP:0002490) | 2.28734980 |
| 37 | Abnormality of the anterior horn cell (HP:0006802) | 2.26570360 |
| 38 | Degeneration of anterior horn cells (HP:0002398) | 2.26570360 |
| 39 | Overlapping toe (HP:0001845) | 2.15944280 |
| 40 | Pelvic girdle muscle weakness (HP:0003749) | 2.15917081 |
| 41 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.14869192 |
| 42 | Mitochondrial inheritance (HP:0001427) | 2.14791539 |
| 43 | Acute encephalopathy (HP:0006846) | 2.13505254 |
| 44 | Reticulocytopenia (HP:0001896) | 2.13158706 |
| 45 | Proximal placement of thumb (HP:0009623) | 2.10355420 |
| 46 | Dry hair (HP:0011359) | 2.02996705 |
| 47 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.02751779 |
| 48 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.02751779 |
| 49 | Acute necrotizing encephalopathy (HP:0006965) | 2.01726715 |
| 50 | Absent radius (HP:0003974) | 2.00850861 |
| 51 | Lactic acidosis (HP:0003128) | 2.00808598 |
| 52 | Pancytopenia (HP:0001876) | 2.00748615 |
| 53 | Squamous cell carcinoma (HP:0002860) | 2.00367571 |
| 54 | Abnormality of the carotid arteries (HP:0005344) | 1.99918449 |
| 55 | Ependymoma (HP:0002888) | 1.99653940 |
| 56 | Failure to thrive in infancy (HP:0001531) | 1.98778775 |
| 57 | Sloping forehead (HP:0000340) | 1.98631424 |
| 58 | Increased nuchal translucency (HP:0010880) | 1.97736652 |
| 59 | Abnormal number of erythroid precursors (HP:0012131) | 1.97506740 |
| 60 | Aplasia involving forearm bones (HP:0009822) | 1.97198812 |
| 61 | Absent forearm bone (HP:0003953) | 1.97198812 |
| 62 | Emotional lability (HP:0000712) | 1.96546949 |
| 63 | Birth length less than 3rd percentile (HP:0003561) | 1.93976644 |
| 64 | Abnormality of reticulocytes (HP:0004312) | 1.93534118 |
| 65 | Spastic paraparesis (HP:0002313) | 1.93502261 |
| 66 | Abnormal lung lobation (HP:0002101) | 1.93389841 |
| 67 | Horseshoe kidney (HP:0000085) | 1.91120700 |
| 68 | Cerebral edema (HP:0002181) | 1.90358243 |
| 69 | Reduced antithrombin III activity (HP:0001976) | 1.89217099 |
| 70 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.88828048 |
| 71 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.88828048 |
| 72 | Decreased lacrimation (HP:0000633) | 1.88452133 |
| 73 | Exercise intolerance (HP:0003546) | 1.84943633 |
| 74 | Reticulocytosis (HP:0001923) | 1.84238260 |
| 75 | Increased intramyocellular lipid droplets (HP:0012240) | 1.82093881 |
| 76 | Triphalangeal thumb (HP:0001199) | 1.81772070 |
| 77 | Lissencephaly (HP:0001339) | 1.79432713 |
| 78 | Brushfield spots (HP:0001088) | 1.78965921 |
| 79 | Deviation of the thumb (HP:0009603) | 1.78873426 |
| 80 | Abnormal hair laboratory examination (HP:0003328) | 1.76727613 |
| 81 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.74617065 |
| 82 | Patellar aplasia (HP:0006443) | 1.74338180 |
| 83 | CNS hypomyelination (HP:0003429) | 1.74051314 |
| 84 | Premature ovarian failure (HP:0008209) | 1.72845662 |
| 85 | Progressive inability to walk (HP:0002505) | 1.71387441 |
| 86 | Short middle phalanx of the 5th finger (HP:0004220) | 1.70771387 |
| 87 | Opisthotonus (HP:0002179) | 1.69949673 |
| 88 | Abnormal gallbladder physiology (HP:0012438) | 1.68749543 |
| 89 | Cholecystitis (HP:0001082) | 1.68749543 |
| 90 | B lymphocytopenia (HP:0010976) | 1.68512205 |
| 91 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.68299025 |
| 92 | Long nose (HP:0003189) | 1.67490102 |
| 93 | Hyperglycinemia (HP:0002154) | 1.66685071 |
| 94 | Poikiloderma (HP:0001029) | 1.66646915 |
| 95 | Prominent metopic ridge (HP:0005487) | 1.63692109 |
| 96 | Choanal atresia (HP:0000453) | 1.62580868 |
| 97 | Bone marrow hypocellularity (HP:0005528) | 1.62026565 |
| 98 | Nephrogenic diabetes insipidus (HP:0009806) | 1.61746982 |
| 99 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.61087333 |
| 100 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.60773490 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SRPK1 | 4.55562561 |
| 2 | BUB1 | 4.52281901 |
| 3 | TRIM28 | 3.08160102 |
| 4 | NEK1 | 3.03665564 |
| 5 | CDC7 | 2.85384059 |
| 6 | TSSK6 | 2.67528053 |
| 7 | BCR | 2.55197279 |
| 8 | STK16 | 2.50290388 |
| 9 | PLK4 | 2.44618941 |
| 10 | EIF2AK1 | 2.29725141 |
| 11 | TESK2 | 2.19819687 |
| 12 | VRK2 | 2.18502327 |
| 13 | BRSK2 | 2.14002848 |
| 14 | TTK | 2.10424111 |
| 15 | SIK3 | 2.05879262 |
| 16 | RPS6KA4 | 2.02057238 |
| 17 | CCNB1 | 1.98896563 |
| 18 | EIF2AK3 | 1.92116434 |
| 19 | BCKDK | 1.85694679 |
| 20 | PBK | 1.74691954 |
| 21 | VRK1 | 1.69001954 |
| 22 | MAP2K7 | 1.65377743 |
| 23 | PLK3 | 1.65155172 |
| 24 | CSNK1A1L | 1.63443062 |
| 25 | CDK8 | 1.55569670 |
| 26 | CSNK1G3 | 1.55409515 |
| 27 | ATR | 1.51522461 |
| 28 | BRSK1 | 1.48381125 |
| 29 | PLK1 | 1.44405600 |
| 30 | PIM2 | 1.40077470 |
| 31 | AURKB | 1.37488122 |
| 32 | MKNK1 | 1.36911036 |
| 33 | STK38L | 1.35047165 |
| 34 | WEE1 | 1.34371719 |
| 35 | CHEK2 | 1.33451469 |
| 36 | SCYL2 | 1.30250397 |
| 37 | CSNK1G1 | 1.28135578 |
| 38 | MAP4K2 | 1.27244964 |
| 39 | BRD4 | 1.24602154 |
| 40 | MAP3K6 | 1.21299526 |
| 41 | CDK12 | 1.13202869 |
| 42 | KSR1 | 1.11779717 |
| 43 | MAP3K5 | 1.05340554 |
| 44 | ZAK | 1.03046730 |
| 45 | DYRK3 | 0.98652994 |
| 46 | CDK7 | 0.97023628 |
| 47 | CHEK1 | 0.96896311 |
| 48 | CSNK1G2 | 0.91708324 |
| 49 | PKN1 | 0.88315402 |
| 50 | TESK1 | 0.87062605 |
| 51 | AURKA | 0.86127969 |
| 52 | RAF1 | 0.83771508 |
| 53 | CLK1 | 0.82886062 |
| 54 | WNK3 | 0.82451228 |
| 55 | ATM | 0.79823746 |
| 56 | DAPK1 | 0.79521295 |
| 57 | CDK6 | 0.76350453 |
| 58 | MINK1 | 0.74960109 |
| 59 | NEK2 | 0.74941060 |
| 60 | NME2 | 0.73349201 |
| 61 | EIF2AK2 | 0.71985390 |
| 62 | DYRK1B | 0.70482252 |
| 63 | MST1R | 0.69048687 |
| 64 | PDK2 | 0.68248697 |
| 65 | CDK4 | 0.67021448 |
| 66 | RPS6KA5 | 0.65533811 |
| 67 | MAP3K4 | 0.64939473 |
| 68 | LIMK1 | 0.61392387 |
| 69 | CDK2 | 0.60512525 |
| 70 | CDK14 | 0.58429970 |
| 71 | CDK18 | 0.56613440 |
| 72 | STK24 | 0.55259712 |
| 73 | NUAK1 | 0.53434336 |
| 74 | CDK9 | 0.51361782 |
| 75 | CDK1 | 0.51002735 |
| 76 | MAP2K4 | 0.50173273 |
| 77 | PASK | 0.49440795 |
| 78 | BMPR1B | 0.49305492 |
| 79 | PLK2 | 0.47937785 |
| 80 | MAP3K10 | 0.47917354 |
| 81 | TAF1 | 0.47375596 |
| 82 | CSNK2A1 | 0.46774513 |
| 83 | ERBB3 | 0.46584239 |
| 84 | CSNK2A2 | 0.45865337 |
| 85 | MKNK2 | 0.45210242 |
| 86 | CDK15 | 0.44645039 |
| 87 | MST4 | 0.42487984 |
| 88 | PAK4 | 0.40244712 |
| 89 | FLT3 | 0.39622866 |
| 90 | NME1 | 0.39216186 |
| 91 | CDK11A | 0.38771514 |
| 92 | MAP3K8 | 0.37191346 |
| 93 | STK4 | 0.31741892 |
| 94 | INSRR | 0.31633951 |
| 95 | MAP3K12 | 0.31257079 |
| 96 | CSNK1E | 0.30650990 |
| 97 | AKT2 | 0.29545986 |
| 98 | EPHA4 | 0.29106648 |
| 99 | ERBB4 | 0.28447717 |
| 100 | LMTK2 | 0.27752422 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 4.33777527 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 3.58954925 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.34152937 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.17746913 |
| 5 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 3.17173883 |
| 6 | Base excision repair_Homo sapiens_hsa03410 | 3.16739797 |
| 7 | Spliceosome_Homo sapiens_hsa03040 | 3.14060402 |
| 8 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.60762908 |
| 9 | RNA transport_Homo sapiens_hsa03013 | 2.51098311 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.49161779 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.45251002 |
| 12 | Cell cycle_Homo sapiens_hsa04110 | 2.39309972 |
| 13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.37163094 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 2.36974729 |
| 15 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.19392509 |
| 16 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.19169445 |
| 17 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.88014612 |
| 18 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.86196821 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.66116602 |
| 20 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.62460431 |
| 21 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.57764761 |
| 22 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.57540263 |
| 23 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.57509040 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.51260907 |
| 25 | Protein export_Homo sapiens_hsa03060 | 1.47277550 |
| 26 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.43608400 |
| 27 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.42811652 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.42184263 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.41604149 |
| 30 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.41387107 |
| 31 | Carbon metabolism_Homo sapiens_hsa01200 | 1.38576178 |
| 32 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.28817023 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.28271070 |
| 34 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.27951684 |
| 35 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.26725061 |
| 36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.26694509 |
| 37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.25972701 |
| 38 | Parkinsons disease_Homo sapiens_hsa05012 | 1.21417290 |
| 39 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.20349077 |
| 40 | Sulfur relay system_Homo sapiens_hsa04122 | 1.19505629 |
| 41 | Huntingtons disease_Homo sapiens_hsa05016 | 1.14583824 |
| 42 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.13168128 |
| 43 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.12654540 |
| 44 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.08471484 |
| 45 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.06626823 |
| 46 | Ribosome_Homo sapiens_hsa03010 | 1.06387389 |
| 47 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.04518761 |
| 48 | Alcoholism_Homo sapiens_hsa05034 | 0.98968440 |
| 49 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.96771389 |
| 50 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.96302989 |
| 51 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.93731580 |
| 52 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.92400579 |
| 53 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.91263312 |
| 54 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.86034163 |
| 55 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.72784629 |
| 56 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.67774373 |
| 57 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65780031 |
| 58 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.63317597 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.61661645 |
| 60 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.61207901 |
| 61 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.60563232 |
| 62 | Lysine degradation_Homo sapiens_hsa00310 | 0.56333698 |
| 63 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.55975873 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54412002 |
| 65 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.54340428 |
| 66 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.53056088 |
| 67 | Shigellosis_Homo sapiens_hsa05131 | 0.50849922 |
| 68 | Alzheimers disease_Homo sapiens_hsa05010 | 0.50331335 |
| 69 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.48981890 |
| 70 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.45354477 |
| 71 | Nicotine addiction_Homo sapiens_hsa05033 | 0.40883593 |
| 72 | Colorectal cancer_Homo sapiens_hsa05210 | 0.38533187 |
| 73 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.38102567 |
| 74 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.37039154 |
| 75 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.33628593 |
| 76 | Peroxisome_Homo sapiens_hsa04146 | 0.31430143 |
| 77 | Bladder cancer_Homo sapiens_hsa05219 | 0.28666719 |
| 78 | Legionellosis_Homo sapiens_hsa05134 | 0.28563218 |
| 79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.25749720 |
| 80 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.25512317 |
| 81 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.25465264 |
| 82 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.25320680 |
| 83 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.24391269 |
| 84 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.24121872 |
| 85 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.24054022 |
| 86 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.22292168 |
| 87 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.21976236 |
| 88 | Thyroid cancer_Homo sapiens_hsa05216 | 0.21641501 |
| 89 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.14631917 |
| 90 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.14456917 |
| 91 | Galactose metabolism_Homo sapiens_hsa00052 | 0.14215748 |
| 92 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.13961146 |
| 93 | Apoptosis_Homo sapiens_hsa04210 | 0.13816451 |
| 94 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.13306613 |
| 95 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.13077082 |
| 96 | Salmonella infection_Homo sapiens_hsa05132 | 0.10050650 |
| 97 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.08136349 |
| 98 | Hepatitis B_Homo sapiens_hsa05161 | 0.07358491 |
| 99 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.07126882 |
| 100 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.04826483 |

