MDN1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)7.35234533
2nuclear pore organization (GO:0006999)7.04330433
3pore complex assembly (GO:0046931)5.57294343
4pre-miRNA processing (GO:0031054)5.31446856
5mitotic sister chromatid cohesion (GO:0007064)4.76924339
6regulation of histone H3-K9 methylation (GO:0051570)4.48327406
7negative regulation of histone methylation (GO:0031061)4.38257047
8regulation of RNA export from nucleus (GO:0046831)4.33044459
9mitotic nuclear envelope disassembly (GO:0007077)4.30172450
10protein complex localization (GO:0031503)4.12099898
11regulation of helicase activity (GO:0051095)4.08564293
12regulation of gene silencing by RNA (GO:0060966)4.08220822
13regulation of posttranscriptional gene silencing (GO:0060147)4.08220822
14regulation of gene silencing by miRNA (GO:0060964)4.08220822
15DNA unwinding involved in DNA replication (GO:0006268)4.06599479
16nuclear envelope disassembly (GO:0051081)4.04606793
17membrane disassembly (GO:0030397)4.04606793
18DNA strand elongation involved in DNA replication (GO:0006271)3.99687350
19DNA synthesis involved in DNA repair (GO:0000731)3.99443524
20non-recombinational repair (GO:0000726)3.94544941
21double-strand break repair via nonhomologous end joining (GO:0006303)3.94544941
22DNA geometric change (GO:0032392)3.91159822
23DNA duplex unwinding (GO:0032508)3.89254536
24regulation of meiosis I (GO:0060631)3.89189010
25IMP biosynthetic process (GO:0006188)3.87891653
26piRNA metabolic process (GO:0034587)3.87624879
27histone H4-K12 acetylation (GO:0043983)3.82601365
28DNA strand elongation (GO:0022616)3.81088504
29protein localization to kinetochore (GO:0034501)3.78607371
30heterochromatin organization (GO:0070828)3.78210042
31DNA replication-dependent nucleosome assembly (GO:0006335)3.77010321
32DNA replication-dependent nucleosome organization (GO:0034723)3.77010321
33dosage compensation (GO:0007549)3.70617519
34mitotic chromosome condensation (GO:0007076)3.69554030
35gene silencing by RNA (GO:0031047)3.65635131
36DNA topological change (GO:0006265)3.62690302
37negative regulation of DNA repair (GO:0045738)3.59622259
38cellular protein complex localization (GO:0034629)3.58526076
39chromatin assembly (GO:0031497)3.50900403
40regulation of translational termination (GO:0006449)3.50476306
41DNA replication checkpoint (GO:0000076)3.47161742
42kinetochore organization (GO:0051383)3.45743104
43histone H3-K36 demethylation (GO:0070544)3.44165544
44negative regulation of chromosome segregation (GO:0051985)3.42570279
45meiotic chromosome segregation (GO:0045132)3.42203251
46regulation of nucleobase-containing compound transport (GO:0032239)3.39961384
47synaptonemal complex assembly (GO:0007130)3.34910949
48DNA replication initiation (GO:0006270)3.34236998
49regulation of centriole replication (GO:0046599)3.31110695
50negative regulation of mitotic sister chromatid separation (GO:2000816)3.31035492
51negative regulation of sister chromatid segregation (GO:0033046)3.31035492
52negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.31035492
53negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.31035492
54negative regulation of mitotic sister chromatid segregation (GO:0033048)3.31035492
55negative regulation of histone modification (GO:0031057)3.30450818
56positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.28061666
57sister chromatid cohesion (GO:0007062)3.27216483
58folic acid-containing compound biosynthetic process (GO:0009396)3.27077786
59positive regulation of SMAD protein import into nucleus (GO:0060391)3.26107040
60DNA methylation involved in gamete generation (GO:0043046)3.25792816
61IMP metabolic process (GO:0046040)3.25166923
62gene silencing (GO:0016458)3.22488794
63regulation of histone methylation (GO:0031060)3.22196078
64regulation of centrosome duplication (GO:0010824)3.22069289
65mRNA transport (GO:0051028)3.21929326
66negative regulation of chromatin modification (GO:1903309)3.21829610
67histone H4-K5 acetylation (GO:0043981)3.21509326
68histone H4-K8 acetylation (GO:0043982)3.21509326
69regulation of histone H3-K4 methylation (GO:0051569)3.21255821
70positive regulation of cell cycle checkpoint (GO:1901978)3.19965243
71protein localization to chromosome, centromeric region (GO:0071459)3.19269361
72regulation of mitotic sister chromatid segregation (GO:0033047)3.18878751
73regulation of sister chromatid segregation (GO:0033045)3.18878751
74regulation of mitotic sister chromatid separation (GO:0010965)3.18878751
75regulation of chromosome segregation (GO:0051983)3.18582559
76histone H2A monoubiquitination (GO:0035518)3.17702915
77cytoplasmic mRNA processing body assembly (GO:0033962)3.16822375
78telomere maintenance via semi-conservative replication (GO:0032201)3.16289834
79histone H3-K9 methylation (GO:0051567)3.16000475
80somatic diversification of immune receptors via somatic mutation (GO:0002566)3.15928663
81somatic hypermutation of immunoglobulin genes (GO:0016446)3.15928663
82spliceosomal tri-snRNP complex assembly (GO:0000244)3.15447345
83regulation of mitotic metaphase/anaphase transition (GO:0030071)3.15391873
84regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.15391873
85regulation of translational fidelity (GO:0006450)3.14541228
86positive regulation of histone H3-K4 methylation (GO:0051571)3.14458567
87DNA conformation change (GO:0071103)3.14425634
88histone mRNA catabolic process (GO:0071044)3.14166210
89attachment of spindle microtubules to kinetochore (GO:0008608)3.13006922
90regulation of mitotic spindle organization (GO:0060236)3.12821348
91negative regulation of mRNA metabolic process (GO:1903312)3.12227810
92mRNA stabilization (GO:0048255)3.10437266
93RNA stabilization (GO:0043489)3.10437266
94mitotic spindle checkpoint (GO:0071174)3.10073943
95regulation of spindle organization (GO:0090224)3.09919342
96positive regulation of histone methylation (GO:0031062)3.09896173
97protein K6-linked ubiquitination (GO:0085020)3.09299921
98snRNA processing (GO:0016180)3.09130466
99regulation of sister chromatid cohesion (GO:0007063)3.08355689
100spindle checkpoint (GO:0031577)3.08269601
101DNA methylation (GO:0006306)3.07849034
102DNA alkylation (GO:0006305)3.07849034
103nuclear envelope organization (GO:0006998)3.07638413
104sister chromatid segregation (GO:0000819)3.06998802
105V(D)J recombination (GO:0033151)3.06966583
106mitotic spindle assembly checkpoint (GO:0007094)3.06887724
107establishment of integrated proviral latency (GO:0075713)3.06659284
108determination of adult lifespan (GO:0008340)3.06156143
109nucleobase biosynthetic process (GO:0046112)3.05393749
110telomere maintenance via recombination (GO:0000722)3.04493143
111positive regulation of chromosome segregation (GO:0051984)3.04007255
112chromatin assembly or disassembly (GO:0006333)3.03887964
113negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.03398685
114negative regulation of translation, ncRNA-mediated (GO:0040033)3.03398685
115regulation of translation, ncRNA-mediated (GO:0045974)3.03398685
116positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.02332527
117positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.02332527
118positive regulation of mitotic sister chromatid separation (GO:1901970)3.02332527
119mitotic recombination (GO:0006312)3.01789468
120ribosome assembly (GO:0042255)3.01006585
121snRNA metabolic process (GO:0016073)3.00707400
122spindle assembly checkpoint (GO:0071173)3.00236864
123negative regulation of DNA recombination (GO:0045910)2.99196403
124reciprocal meiotic recombination (GO:0007131)2.98824964
125reciprocal DNA recombination (GO:0035825)2.98824964
126nucleic acid transport (GO:0050657)2.98708516
127RNA transport (GO:0050658)2.98708516
128establishment of RNA localization (GO:0051236)2.98708516
129metaphase plate congression (GO:0051310)2.98139709
130regulation of DNA endoreduplication (GO:0032875)2.97702091
131mitotic metaphase plate congression (GO:0007080)2.96770722
132regulation of gene silencing (GO:0060968)2.96372693
133inner cell mass cell proliferation (GO:0001833)2.95621817
134regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.95531418
135negative regulation of DNA-dependent DNA replication (GO:2000104)2.95496469
136monoubiquitinated protein deubiquitination (GO:0035520)2.95072375
137negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.94899845
138regulation of protein polyubiquitination (GO:1902914)2.93209119
139ATP-dependent chromatin remodeling (GO:0043044)2.93126807
140negative regulation of mRNA processing (GO:0050686)2.92862914
141maturation of SSU-rRNA (GO:0030490)2.92229816
142regulation of centrosome cycle (GO:0046605)2.92168425
143regulation of DNA damage checkpoint (GO:2000001)2.91577443
144ribosome biogenesis (GO:0042254)2.91529280
145mitotic sister chromatid segregation (GO:0000070)2.91514403
146ncRNA catabolic process (GO:0034661)2.90273129
147mRNA export from nucleus (GO:0006406)2.89892289

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.70137810
2E2F4_17652178_ChIP-ChIP_JURKAT_Human4.22292150
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.54645710
4* MYC_18555785_ChIP-Seq_MESCs_Mouse3.46767905
5* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.38356153
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.13692440
7SALL1_21062744_ChIP-ChIP_HESCs_Human3.00564711
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.79501601
9MYC_19079543_ChIP-ChIP_MESCs_Mouse2.72891632
10MYC_22102868_ChIP-Seq_BL_Human2.58746158
11E2F1_21310950_ChIP-Seq_MCF-7_Human2.55348152
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.39950552
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.30616005
14BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.06356943
15NELFA_20434984_ChIP-Seq_ESCs_Mouse2.05126428
16E2F7_22180533_ChIP-Seq_HELA_Human11.1397123
17AR_21909140_ChIP-Seq_LNCAP_Human1.99165420
18MYCN_18555785_ChIP-Seq_MESCs_Mouse1.94932492
19* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92252152
20SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.91513575
21YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.89390927
22POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.88207348
23CIITA_25753668_ChIP-Seq_RAJI_Human1.86643804
24EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.84922624
25GATA1_22025678_ChIP-Seq_K562_Human1.81026041
26NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.79713237
27KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.75806223
28KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.75806223
29KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.75806223
30TP63_19390658_ChIP-ChIP_HaCaT_Human1.70360254
31KDM5A_27292631_Chip-Seq_BREAST_Human1.64700929
32XRN2_22483619_ChIP-Seq_HELA_Human1.64249031
33MYC_18358816_ChIP-ChIP_MESCs_Mouse1.63481468
34NOTCH1_21737748_ChIP-Seq_TLL_Human1.52858513
35VDR_23849224_ChIP-Seq_CD4+_Human1.52279245
36ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.52217987
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.50855242
38* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.46176651
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42553528
40ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.42229837
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.41727515
42EST1_17652178_ChIP-ChIP_JURKAT_Human1.41077351
43* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.39142014
44NANOG_18555785_ChIP-Seq_MESCs_Mouse1.37647627
45RBPJ_22232070_ChIP-Seq_NCS_Mouse1.37591147
46FOXP3_21729870_ChIP-Seq_TREG_Human1.36837105
47SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.34010723
48CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.33561825
49PADI4_21655091_ChIP-ChIP_MCF-7_Human1.31409289
50ETS1_20019798_ChIP-Seq_JURKAT_Human1.27849583
51STAT3_1855785_ChIP-Seq_MESCs_Mouse1.26165824
52TTF2_22483619_ChIP-Seq_HELA_Human1.23264435
53ELK1_19687146_ChIP-ChIP_HELA_Human1.22826983
54* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.21865554
55FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.20895039
56SOX2_16153702_ChIP-ChIP_HESCs_Human1.20597830
57STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.19815165
58POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.18007964
59SOX2_18555785_ChIP-Seq_MESCs_Mouse1.15502226
60HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.15216715
61TFEB_21752829_ChIP-Seq_HELA_Human1.14049623
62NANOG_16153702_ChIP-ChIP_HESCs_Human1.13086133
63TCF7_22412390_ChIP-Seq_EML_Mouse1.12497788
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.11603797
65DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.11205185
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.10736817
67ESR1_15608294_ChIP-ChIP_MCF-7_Human1.09904871
68TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.09596717
69CREB1_15753290_ChIP-ChIP_HEK293T_Human1.09320614
70* HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.08506192
71THAP11_20581084_ChIP-Seq_MESCs_Mouse1.07521158
72PKCTHETA_26484144_Chip-Seq_BREAST_Human1.06380915
73KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.05635027
74SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.05493179
75* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.05330807
76GABP_19822575_ChIP-Seq_HepG2_Human1.05010046
77* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.04026217
78MYB_26560356_Chip-Seq_TH1_Human1.02049103
79E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01294626
80ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.01239545
81SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.00502413
82ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00103890
83* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.99950777
84TCF3_18692474_ChIP-Seq_MESCs_Mouse0.98749519
85DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.98323263
86VDR_21846776_ChIP-Seq_THP-1_Human0.96003352
87POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.92553064
88DCP1A_22483619_ChIP-Seq_HELA_Human0.92129111
89ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.91589670
90* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.91341944
91NANOG_21062744_ChIP-ChIP_HESCs_Human0.91086682
92NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.90436304
93UTX_26944678_Chip-Seq_JUKART_Human0.90252736
94E2F1_18555785_ChIP-Seq_MESCs_Mouse0.88945576
95CHD1_26751641_Chip-Seq_LNCaP_Human0.87845954
96KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.87425166
97ERG_20887958_ChIP-Seq_HPC-7_Mouse0.86699392
98PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.86146511
99HOXB4_20404135_ChIP-ChIP_EML_Mouse0.85694847
100SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.85145039
101GABP_17652178_ChIP-ChIP_JURKAT_Human0.83837929
102TCF3_18692474_ChIP-Seq_MEFs_Mouse0.83570844
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.83400469
104TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.82365099
105* JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.81832017
106KDM2B_26808549_Chip-Seq_DND41_Human0.81778361
107FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.80946212
108FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.80230511
109DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.79795559
110TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.79780888
111MAF_26560356_Chip-Seq_TH1_Human0.78356306
112MYB_26560356_Chip-Seq_TH2_Human0.78043230
113SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.77649817
114SOX17_20123909_ChIP-Seq_XEN_Mouse0.76896403
115FUS_26573619_Chip-Seq_HEK293_Human0.76022850
116POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.73168590
117NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.73132239
118KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.72248524
119GATA1_26923725_Chip-Seq_HPCs_Mouse0.72106556
120* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.71484690
121NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.70399480

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.84410264
2MP0008877_abnormal_DNA_methylation4.70748660
3MP0010094_abnormal_chromosome_stability4.33729124
4MP0003111_abnormal_nucleus_morphology3.96568431
5MP0003693_abnormal_embryo_hatching3.55787489
6MP0003077_abnormal_cell_cycle3.38202535
7MP0008058_abnormal_DNA_repair3.24820324
8MP0004957_abnormal_blastocyst_morpholog3.21296872
9MP0010352_gastrointestinal_tract_polyps2.95889284
10MP0010307_abnormal_tumor_latency2.87370755
11MP0002396_abnormal_hematopoietic_system2.40782832
12MP0003123_paternal_imprinting2.37516698
13MP0005076_abnormal_cell_differentiation2.34568953
14MP0001730_embryonic_growth_arrest2.33513955
15MP0003786_premature_aging2.31009943
16MP0000350_abnormal_cell_proliferation2.23487912
17MP0008007_abnormal_cellular_replicative2.19122331
18MP0003121_genomic_imprinting2.16865352
19MP0000569_abnormal_digit_pigmentation2.07305984
20MP0009697_abnormal_copulation1.99241430
21MP0003787_abnormal_imprinting1.97698853
22MP0001672_abnormal_embryogenesis/_devel1.96191609
23MP0005380_embryogenesis_phenotype1.96191609
24MP0003890_abnormal_embryonic-extraembry1.93362175
25MP0004808_abnormal_hematopoietic_stem1.89384879
26MP0004197_abnormal_fetal_growth/weight/1.88933017
27MP0008995_early_reproductive_senescence1.88814111
28MP0002084_abnormal_developmental_patter1.84387669
29MP0001661_extended_life_span1.82599155
30MP0003984_embryonic_growth_retardation1.82131930
31MP0002210_abnormal_sex_determination1.81020839
32MP0004185_abnormal_adipocyte_glucose1.80424899
33MP0002088_abnormal_embryonic_growth/wei1.77778502
34MP0002085_abnormal_embryonic_tissue1.67012876
35MP0002086_abnormal_extraembryonic_tissu1.67011079
36MP0001697_abnormal_embryo_size1.65207638
37MP0008932_abnormal_embryonic_tissue1.63590194
38MP0003763_abnormal_thymus_physiology1.55498122
39MP0001145_abnormal_male_reproductive1.53100741
40MP0002254_reproductive_system_inflammat1.51042653
41MP0001929_abnormal_gametogenesis1.50838675
42MP0002080_prenatal_lethality1.46890997
43MP0001293_anophthalmia1.36096483
44MP0000703_abnormal_thymus_morphology1.29847509
45MP0000313_abnormal_cell_death1.29197161
46MP0000653_abnormal_sex_gland1.29046255
47MP0009703_decreased_birth_body1.19482594
48MP0002019_abnormal_tumor_incidence1.19185850
49MP0002166_altered_tumor_susceptibility1.17897757
50MP0009672_abnormal_birth_weight1.16309719
51MP0003718_maternal_effect1.15641510
52MP0003705_abnormal_hypodermis_morpholog1.13171365
53MP0002398_abnormal_bone_marrow1.09376777
54MP0003567_abnormal_fetal_cardiomyocyte1.06749672
55MP0000490_abnormal_crypts_of1.06282400
56MP0001915_intracranial_hemorrhage1.05104757
57MP0001299_abnormal_eye_distance/1.04587790
58MP0009278_abnormal_bone_marrow1.03573445
59MP0003698_abnormal_male_reproductive1.01695994
60MP0002006_tumorigenesis1.00447784
61MP0010630_abnormal_cardiac_muscle0.99555272
62MP0005397_hematopoietic_system_phenotyp0.95563396
63MP0001545_abnormal_hematopoietic_system0.95563396
64MP0010234_abnormal_vibrissa_follicle0.93129994
65MP0001286_abnormal_eye_development0.92293478
66MP0003943_abnormal_hepatobiliary_system0.89350535
67MP0002722_abnormal_immune_system0.88160393
68MP0002009_preneoplasia0.87913133
69MP0003119_abnormal_digestive_system0.87691138
70MP0000689_abnormal_spleen_morphology0.85277815
71MP0005621_abnormal_cell_physiology0.84892844
72MP0003566_abnormal_cell_adhesion0.84479629
73MP0002697_abnormal_eye_size0.84266222
74MP0001849_ear_inflammation0.84044165
75MP0000432_abnormal_head_morphology0.83158535
76MP0000428_abnormal_craniofacial_morphol0.83036777
77MP0003937_abnormal_limbs/digits/tail_de0.81885808
78MP0002092_abnormal_eye_morphology0.80614670
79MP0001188_hyperpigmentation0.80201959
80MP0002925_abnormal_cardiovascular_devel0.79034667
81MP0005384_cellular_phenotype0.77449246
82MP0000733_abnormal_muscle_development0.76547009
83MP0001119_abnormal_female_reproductive0.76527600
84MP0005023_abnormal_wound_healing0.76491129
85MP0002796_impaired_skin_barrier0.76073787
86MP0002877_abnormal_melanocyte_morpholog0.75956080
87MP0001873_stomach_inflammation0.74800911
88MP0010678_abnormal_skin_adnexa0.74054108
89MP0001800_abnormal_humoral_immune0.73900052
90MP0000371_diluted_coat_color0.73569426
91MP0000537_abnormal_urethra_morphology0.73164571
92MP0003935_abnormal_craniofacial_develop0.73111875
93MP0003861_abnormal_nervous_system0.72910500
94MP0005623_abnormal_meninges_morphology0.72786099
95MP0003646_muscle_fatigue0.72559381
96MP0003300_gastrointestinal_ulcer0.72444061
97MP0002269_muscular_atrophy0.71839261
98MP0000383_abnormal_hair_follicle0.71633651
99MP0003221_abnormal_cardiomyocyte_apopto0.71133889
100MP0000579_abnormal_nail_morphology0.68987895
101MP0002075_abnormal_coat/hair_pigmentati0.68827086
102MP0003941_abnormal_skin_development0.68463709
103MP0003115_abnormal_respiratory_system0.68362600
104MP0003936_abnormal_reproductive_system0.67519369
105MP0006035_abnormal_mitochondrial_morpho0.66834801
106MP0000358_abnormal_cell_content/0.65706036
107MP0002161_abnormal_fertility/fecundity0.65518451
108MP0004233_abnormal_muscle_weight0.65287186
109MP0002429_abnormal_blood_cell0.64158083
110MP0002160_abnormal_reproductive_system0.63932042
111MP0008770_decreased_survivor_rate0.63761066
112MP0000716_abnormal_immune_system0.62622745
113MP0005377_hearing/vestibular/ear_phenot0.61673086
114MP0003878_abnormal_ear_physiology0.61673086
115MP0002111_abnormal_tail_morphology0.61554873
116MP0004087_abnormal_muscle_fiber0.59385253
117MP0003091_abnormal_cell_migration0.58999394
118MP0002114_abnormal_axial_skeleton0.58625623
119MP0005174_abnormal_tail_pigmentation0.58478927
120MP0002081_perinatal_lethality0.58296613
121MP0003136_yellow_coat_color0.58212363
122MP0005666_abnormal_adipose_tissue0.55199138
123MP0005220_abnormal_exocrine_pancreas0.54749720
124MP0000266_abnormal_heart_morphology0.54586567
125MP0004264_abnormal_extraembryonic_tissu0.54420079
126MP0003699_abnormal_female_reproductive0.54352753
127MP0005501_abnormal_skin_physiology0.53721272
128MP0005187_abnormal_penis_morphology0.53388230

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.12571846
2Chromsome breakage (HP:0040012)4.02207965
3Nephroblastoma (Wilms tumor) (HP:0002667)3.90048869
4Medulloblastoma (HP:0002885)3.75103990
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.73965574
6Abnormality of the fingertips (HP:0001211)3.66005845
7Embryonal renal neoplasm (HP:0011794)3.62895153
8Volvulus (HP:0002580)3.49429894
9Astrocytoma (HP:0009592)3.40594791
10Abnormality of the astrocytes (HP:0100707)3.40594791
11Hepatoblastoma (HP:0002884)3.27130525
12Abnormality of the labia minora (HP:0012880)3.25893148
13Neoplasm of the oral cavity (HP:0100649)3.06572442
14Abnormality of chromosome stability (HP:0003220)3.04299717
15Dysmetric saccades (HP:0000641)3.02837719
16Glioma (HP:0009733)2.99343600
17Ectopic kidney (HP:0000086)2.94601474
18Rhabdomyosarcoma (HP:0002859)2.90421475
19Agnosia (HP:0010524)2.88979728
20Prominent nose (HP:0000448)2.82491208
21Colon cancer (HP:0003003)2.78292673
22Urethral obstruction (HP:0000796)2.75747629
23Basal cell carcinoma (HP:0002671)2.74770844
24Long eyelashes (HP:0000527)2.70247776
25Selective tooth agenesis (HP:0001592)2.67017169
26Neonatal hypoglycemia (HP:0001998)2.61097541
27Neoplasm of striated muscle (HP:0009728)2.59814375
28Increased nuchal translucency (HP:0010880)2.54776935
29Impulsivity (HP:0100710)2.54422937
30Heterotopia (HP:0002282)2.54420218
31Proximal placement of thumb (HP:0009623)2.45237049
32Deviation of the thumb (HP:0009603)2.43746603
33Biliary tract neoplasm (HP:0100574)2.38761557
3411 pairs of ribs (HP:0000878)2.38554681
35Abnormality of the lower motor neuron (HP:0002366)2.38134458
36Supernumerary ribs (HP:0005815)2.34893088
37Aplasia/Hypoplasia of the uvula (HP:0010293)2.33167442
38Amaurosis fugax (HP:0100576)2.31645823
39Abnormality of the preputium (HP:0100587)2.30152922
40Abnormality of cochlea (HP:0000375)2.29575509
41Short 4th metacarpal (HP:0010044)2.29292024
42Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.29292024
43Absent frontal sinuses (HP:0002688)2.28604465
44Embryonal neoplasm (HP:0002898)2.26764868
45Meckel diverticulum (HP:0002245)2.26518888
46Myelodysplasia (HP:0002863)2.26304616
47Progressive external ophthalmoplegia (HP:0000590)2.25685084
48Spastic diplegia (HP:0001264)2.25197937
49Cafe-au-lait spot (HP:0000957)2.22919024
50Hyperacusis (HP:0010780)2.22847764
51Anal stenosis (HP:0002025)2.22576170
52Sandal gap (HP:0001852)2.21534864
53Abnormality of the carotid arteries (HP:0005344)2.16900126
54Supernumerary bones of the axial skeleton (HP:0009144)2.16515844
55Neoplasm of the adrenal cortex (HP:0100641)2.16027147
56Abnormal spermatogenesis (HP:0008669)2.15690620
57Abnormality of the ileum (HP:0001549)2.15637921
58Abnormal number of incisors (HP:0011064)2.15302739
59Truncal obesity (HP:0001956)2.13510568
60Abnormality of DNA repair (HP:0003254)2.10164457
61Protruding tongue (HP:0010808)2.09576960
62Aplasia/Hypoplasia of the sternum (HP:0006714)2.09431465
63Absent thumb (HP:0009777)2.07621723
64High anterior hairline (HP:0009890)2.06678389
65Missing ribs (HP:0000921)2.05171971
66Low anterior hairline (HP:0000294)2.05033602
67Macroorchidism (HP:0000053)2.02152301
68Acute myeloid leukemia (HP:0004808)1.99433042
69Skull defect (HP:0001362)1.98941872
70Facial hemangioma (HP:0000329)1.98231987
71Progressive muscle weakness (HP:0003323)1.97228444
72Sloping forehead (HP:0000340)1.96969742
73Homocystinuria (HP:0002156)1.95770901
74Abnormality of homocysteine metabolism (HP:0010919)1.95770901
75Neoplasm of the small intestine (HP:0100833)1.95704312
76Abnormality of chromosome segregation (HP:0002916)1.95045453
77Multiple enchondromatosis (HP:0005701)1.94465864
78Abnormality of the salivary glands (HP:0010286)1.93423682
79Obsessive-compulsive behavior (HP:0000722)1.93249382
80Cortical dysplasia (HP:0002539)1.93195841
81Malignant gastrointestinal tract tumors (HP:0006749)1.92499915
82Gastrointestinal carcinoma (HP:0002672)1.92499915
83Renovascular hypertension (HP:0100817)1.91971753
84Small intestinal stenosis (HP:0012848)1.91384241
85Duodenal stenosis (HP:0100867)1.91384241
86Diastasis recti (HP:0001540)1.91310939
87Birth length less than 3rd percentile (HP:0003561)1.90767348
88Narrow palate (HP:0000189)1.90516727
89Trigonocephaly (HP:0000243)1.89149225
90Short chin (HP:0000331)1.88435606
91IgA deficiency (HP:0002720)1.88362132
92Persistence of primary teeth (HP:0006335)1.87125613
93Azoospermia (HP:0000027)1.85117227
94Supernumerary spleens (HP:0009799)1.84859015
95Ankyloglossia (HP:0010296)1.84803086
96Papillary thyroid carcinoma (HP:0002895)1.82079304
97Absent radius (HP:0003974)1.81506018
98Vertebral arch anomaly (HP:0008438)1.81437072
99Partial agenesis of the corpus callosum (HP:0001338)1.81235974
100Deep philtrum (HP:0002002)1.81229146
101Facial cleft (HP:0002006)1.80727261
102Hypopigmentation of the fundus (HP:0007894)1.80251754
103T lymphocytopenia (HP:0005403)1.80157620
104Reticulocytopenia (HP:0001896)1.79936721
105Overlapping toe (HP:0001845)1.79219648
106Sparse lateral eyebrow (HP:0005338)1.78323869
107Abnormal lung lobation (HP:0002101)1.77149545
108Clitoromegaly (HP:0000057)1.77046176
109Spinal muscular atrophy (HP:0007269)1.76766184
110Capillary hemangiomas (HP:0005306)1.76475540
111Squamous cell carcinoma (HP:0002860)1.76419763
112Pelvic girdle muscle weakness (HP:0003749)1.75376317
113Leiomyosarcoma (HP:0100243)1.74915350
114Uterine leiomyosarcoma (HP:0002891)1.74915350
115Neuroblastic tumors (HP:0004376)1.74275938
116Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.74275938
117Neuroblastoma (HP:0003006)1.74275938
118Primitive neuroectodermal tumor (HP:0030065)1.74275938
119Abnormality of the nasal septum (HP:0000419)1.74011190
120Intestinal fistula (HP:0100819)1.72980151
121High pitched voice (HP:0001620)1.72805421
122Patellar aplasia (HP:0006443)1.71153071
123Broad palm (HP:0001169)1.71055167
124Abnormal hair whorl (HP:0010721)1.70348985
125Abnormality of the duodenum (HP:0002246)1.68453876
126Duplicated collecting system (HP:0000081)1.68194699
127Cutaneous melanoma (HP:0012056)1.68171898
128Aplasia involving forearm bones (HP:0009822)1.67728873
129Absent forearm bone (HP:0003953)1.67728873
130Choanal atresia (HP:0000453)1.67012818
131Short thumb (HP:0009778)1.66533060
132Degeneration of anterior horn cells (HP:0002398)1.66231804
133Abnormality of the anterior horn cell (HP:0006802)1.66231804
134Cutis marmorata (HP:0000965)1.65534678
135Limited elbow extension (HP:0001377)1.64407813
136Pseudobulbar signs (HP:0002200)1.64215264
137Skin tags (HP:0010609)1.64154750
138Neoplasm of the colon (HP:0100273)1.63538055
139Wide nose (HP:0000445)1.62756953
140IgM deficiency (HP:0002850)1.62350662
141Clubbing of toes (HP:0100760)1.62335898
142Underdeveloped nasal alae (HP:0000430)1.61990500
143Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.61802474
144Neoplasm of the pancreas (HP:0002894)1.61408774
145Broad thumb (HP:0011304)1.61101007
146Acute lymphatic leukemia (HP:0006721)1.60123497

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK126.70466457
2CDC74.55184134
3BRD43.59716217
4WEE12.48216531
5TSSK62.40784380
6EEF2K2.32366521
7NEK22.31226231
8SRPK12.13396468
9ATR2.11419054
10SMG12.10716856
11TTK1.85271230
12PNCK1.82363421
13CHEK11.80447039
14MKNK21.74579240
15CDK41.73770669
16ACVR1B1.69329739
17CDK71.65213393
18ALK1.64196449
19PBK1.62782232
20CAMK1D1.62154222
21PASK1.56340884
22MKNK11.53934014
23ATM1.52012027
24RPS6KB21.50403304
25MAP3K101.49353495
26MTOR1.49256761
27CHEK21.49117435
28PLK11.48836722
29CDK91.42733894
30EPHA21.40154682
31MAP4K11.39413332
32SCYL21.39199263
33PLK31.37040781
34TAF11.36269339
35CAMK1G1.26187116
36AURKB1.25760852
37CDK21.23527978
38NLK1.20188014
39LATS11.19232837
40TGFBR11.18218264
41FGFR41.16137120
42STK41.12803397
43STK31.10461154
44PKN21.08713220
45PIM11.07992306
46STK101.07316730
47TRIB31.06965245
48MELK1.02734697
49TLK11.02477454
50CDK61.00489122
51ZAK0.99878869
52MAP3K80.99869680
53BUB10.96626537
54CDK10.93589416
55CHUK0.91884013
56BRSK20.90263741
57CSNK1D0.89626893
58RPS6KA40.88888216
59ICK0.86978809
60JAK30.84789548
61PLK40.84786332
62EIF2AK30.83569997
63PRKDC0.80967043
64FGFR30.79994329
65PDGFRA0.79251479
66FGFR10.78424111
67CSNK1E0.76787961
68TNIK0.75423997
69MAP3K90.73300571
70MAPK140.72293992
71RPS6KB10.68564502
72SGK20.63785965
73NUAK10.63287687
74GSK3B0.62121032
75NEK10.59274918
76LATS20.58686623
77SIK20.58364916
78EIF2AK20.57562519
79ERBB40.57128203
80* CSNK2A20.56987581
81PRPF4B0.55744456
82RPS6KA50.55724650
83TEC0.54803447
84DYRK30.53156368
85TTN0.52072085
86BMX0.50779121
87FLT30.50589340
88MAPK10.49821624
89PAK20.49589794
90SGK30.49209336
91STK240.49148022
92TYRO30.49110852
93BRSK10.48878938
94STK38L0.47290080
95MARK30.46728883
96MAPK100.46567718
97MAPK80.45760644
98MAPK110.44946894
99MAP2K30.44040134
100AKT10.43289030
101TRPM70.43085556
102PDGFRB0.41637132
103VRK10.41325475
104AKT30.38876081
105NEK60.38448001
106CDC42BPA0.38349571
107SGK10.37750281
108ZAP700.37179050
109TXK0.35052447
110FGFR20.34240770
111AKT20.33714419
112NME10.33414433
113CDK30.33396226
114RAF10.32960427
115AURKA0.32878512
116KSR20.32768032
117CLK10.32392996
118WNK10.32379906
119MAP3K70.31901713
120PRKAA10.30923917
121YES10.30727939
122RPS6KA10.30627342
123CSF1R0.30570171
124PRKAA20.29906888
125MAP3K140.28660170
126HCK0.28357481
127EIF2AK10.27951053
128LCK0.27633545
129GRK60.27105146
130IKBKB0.26481395
131MAP3K40.25419513
132RIPK10.25142484
133TAOK10.24714994

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.02105210
2Mismatch repair_Homo sapiens_hsa034303.47950471
3DNA replication_Homo sapiens_hsa030303.25312932
4RNA transport_Homo sapiens_hsa030133.16739689
5One carbon pool by folate_Homo sapiens_hsa006702.81580197
6Spliceosome_Homo sapiens_hsa030402.80126594
7mRNA surveillance pathway_Homo sapiens_hsa030152.57081579
8Fanconi anemia pathway_Homo sapiens_hsa034602.50808968
9Cell cycle_Homo sapiens_hsa041102.46694901
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.38976167
11Homologous recombination_Homo sapiens_hsa034402.23923269
12Non-homologous end-joining_Homo sapiens_hsa034502.19496996
13Base excision repair_Homo sapiens_hsa034102.17558988
14Nucleotide excision repair_Homo sapiens_hsa034202.11937472
15Basal transcription factors_Homo sapiens_hsa030221.99351033
16RNA polymerase_Homo sapiens_hsa030201.93923671
17RNA degradation_Homo sapiens_hsa030181.87714190
18Systemic lupus erythematosus_Homo sapiens_hsa053221.74859526
19Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.60302228
20Lysine degradation_Homo sapiens_hsa003101.52836579
21Viral carcinogenesis_Homo sapiens_hsa052031.46496437
22MicroRNAs in cancer_Homo sapiens_hsa052061.36291213
23Cysteine and methionine metabolism_Homo sapiens_hsa002701.35926705
24Herpes simplex infection_Homo sapiens_hsa051681.34618214
25p53 signaling pathway_Homo sapiens_hsa041151.29954296
26Antigen processing and presentation_Homo sapiens_hsa046121.26393208
27HTLV-I infection_Homo sapiens_hsa051661.25280036
28Transcriptional misregulation in cancer_Homo sapiens_hsa052021.24811371
29Epstein-Barr virus infection_Homo sapiens_hsa051691.21455559
30Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.16550483
31Pyrimidine metabolism_Homo sapiens_hsa002401.11225621
32Primary immunodeficiency_Homo sapiens_hsa053401.08219250
33NF-kappa B signaling pathway_Homo sapiens_hsa040641.08054711
34Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07034493
35Oocyte meiosis_Homo sapiens_hsa041141.06586504
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.06122499
37Notch signaling pathway_Homo sapiens_hsa043301.05231811
38Small cell lung cancer_Homo sapiens_hsa052221.03861721
39Vitamin B6 metabolism_Homo sapiens_hsa007501.02155592
40mTOR signaling pathway_Homo sapiens_hsa041501.00199790
41Biosynthesis of amino acids_Homo sapiens_hsa012300.98987350
42Colorectal cancer_Homo sapiens_hsa052100.96808896
43Chronic myeloid leukemia_Homo sapiens_hsa052200.96210514
44T cell receptor signaling pathway_Homo sapiens_hsa046600.91849717
45Thyroid cancer_Homo sapiens_hsa052160.89477015
46Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.88054110
47Thyroid hormone signaling pathway_Homo sapiens_hsa049190.87997665
48TGF-beta signaling pathway_Homo sapiens_hsa043500.87445195
49Alcoholism_Homo sapiens_hsa050340.86658589
50Adherens junction_Homo sapiens_hsa045200.85006184
51Selenocompound metabolism_Homo sapiens_hsa004500.83704351
52Basal cell carcinoma_Homo sapiens_hsa052170.82044495
53Acute myeloid leukemia_Homo sapiens_hsa052210.80748455
54Dorso-ventral axis formation_Homo sapiens_hsa043200.80743317
55B cell receptor signaling pathway_Homo sapiens_hsa046620.79788740
56Hippo signaling pathway_Homo sapiens_hsa043900.72325611
57Central carbon metabolism in cancer_Homo sapiens_hsa052300.71878872
58Influenza A_Homo sapiens_hsa051640.71575172
59Measles_Homo sapiens_hsa051620.71525697
60Prostate cancer_Homo sapiens_hsa052150.71345864
61Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.69345662
62Hepatitis B_Homo sapiens_hsa051610.67599638
63NOD-like receptor signaling pathway_Homo sapiens_hsa046210.65507228
64Insulin signaling pathway_Homo sapiens_hsa049100.64704048
65Fatty acid biosynthesis_Homo sapiens_hsa000610.64496992
66Ribosome_Homo sapiens_hsa030100.63898826
67Viral myocarditis_Homo sapiens_hsa054160.63809522
68Pathways in cancer_Homo sapiens_hsa052000.62224177
69Non-small cell lung cancer_Homo sapiens_hsa052230.61971209
70Cyanoamino acid metabolism_Homo sapiens_hsa004600.60679778
71Pancreatic cancer_Homo sapiens_hsa052120.60349598
72Wnt signaling pathway_Homo sapiens_hsa043100.58949864
73Choline metabolism in cancer_Homo sapiens_hsa052310.58594042
74Long-term potentiation_Homo sapiens_hsa047200.57554984
75Purine metabolism_Homo sapiens_hsa002300.56821670
76Renal cell carcinoma_Homo sapiens_hsa052110.56205992
77Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.55082817
78Endometrial cancer_Homo sapiens_hsa052130.53510612
79Proteoglycans in cancer_Homo sapiens_hsa052050.52728141
80Bladder cancer_Homo sapiens_hsa052190.52469954
81Glucagon signaling pathway_Homo sapiens_hsa049220.52459703
82Apoptosis_Homo sapiens_hsa042100.50891108
83Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.50225006
84FoxO signaling pathway_Homo sapiens_hsa040680.49997785
85Neurotrophin signaling pathway_Homo sapiens_hsa047220.48491113
86AMPK signaling pathway_Homo sapiens_hsa041520.47031140
87HIF-1 signaling pathway_Homo sapiens_hsa040660.46363006
88Melanoma_Homo sapiens_hsa052180.46345536
89Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45264959
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.45076536
91Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.44855073
92Longevity regulating pathway - mammal_Homo sapiens_hsa042110.44540569
932-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.43729465
94Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.43605589
95Toxoplasmosis_Homo sapiens_hsa051450.42603479
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.42052530
97Inositol phosphate metabolism_Homo sapiens_hsa005620.41376521
98Hematopoietic cell lineage_Homo sapiens_hsa046400.41368243
99Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.40632750
100Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.39327926
101Hedgehog signaling pathway_Homo sapiens_hsa043400.39241182
102Pyruvate metabolism_Homo sapiens_hsa006200.38056139
103Insulin resistance_Homo sapiens_hsa049310.37006899
104Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.36963281
105Legionellosis_Homo sapiens_hsa051340.36950590
106Type I diabetes mellitus_Homo sapiens_hsa049400.36929860
107Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.36866190
108Arginine biosynthesis_Homo sapiens_hsa002200.36661968
109AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35236937
110Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.34681317
111Type II diabetes mellitus_Homo sapiens_hsa049300.34111565
112Carbon metabolism_Homo sapiens_hsa012000.33992066
113MAPK signaling pathway_Homo sapiens_hsa040100.33804338
114Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.33211121
115Estrogen signaling pathway_Homo sapiens_hsa049150.33129430
116Osteoclast differentiation_Homo sapiens_hsa043800.32985982
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.32965437
118Prolactin signaling pathway_Homo sapiens_hsa049170.32340783
119RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.31680721
120Glioma_Homo sapiens_hsa052140.31497893
121Tight junction_Homo sapiens_hsa045300.30040943
122VEGF signaling pathway_Homo sapiens_hsa043700.29609049
123TNF signaling pathway_Homo sapiens_hsa046680.29230386
124Regulation of actin cytoskeleton_Homo sapiens_hsa048100.28906738
125PI3K-Akt signaling pathway_Homo sapiens_hsa041510.28466062
126Thyroid hormone synthesis_Homo sapiens_hsa049180.28442269
127ErbB signaling pathway_Homo sapiens_hsa040120.28027057
128Leukocyte transendothelial migration_Homo sapiens_hsa046700.26544623
129Focal adhesion_Homo sapiens_hsa045100.25490363

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