MED15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.01916367
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.01916367
3antigen processing and presentation of endogenous antigen (GO:0019883)4.36277214
4modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.32235300
5modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.32235300
6positive regulation by organism of defense response of other organism involved in symbiotic interact4.32235300
7modulation by symbiont of host immune response (GO:0052553)4.32235300
8positive regulation by symbiont of host defense response (GO:0052509)4.32235300
9modulation by symbiont of host defense response (GO:0052031)4.32235300
10positive regulation of gamma-delta T cell activation (GO:0046645)4.21493392
11regulation of interleukin-12 biosynthetic process (GO:0045075)4.05619830
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.71004340
13regulation of gamma-delta T cell differentiation (GO:0045586)3.67273712
14regulation of interferon-beta biosynthetic process (GO:0045357)3.62036056
15antigen processing and presentation via MHC class Ib (GO:0002475)3.56242206
16immunoglobulin mediated immune response (GO:0016064)3.44025812
17regulation of gamma-delta T cell activation (GO:0046643)3.39214068
18response to peptidoglycan (GO:0032494)3.34184500
19negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.30217214
20negative regulation of cell killing (GO:0031342)3.30217214
21NIK/NF-kappaB signaling (GO:0038061)3.29700416
22macrophage activation involved in immune response (GO:0002281)3.21485390
23germinal center formation (GO:0002467)3.19814886
24positive regulation of interferon-alpha production (GO:0032727)3.08165641
25positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.05642695
26positive regulation of histone deacetylation (GO:0031065)3.03907673
27detection of bacterium (GO:0016045)3.02675791
28regulation of type I interferon-mediated signaling pathway (GO:0060338)3.01006854
29response to type I interferon (GO:0034340)3.00618674
30regulation of B cell receptor signaling pathway (GO:0050855)3.00309149
31neutrophil activation involved in immune response (GO:0002283)2.97273600
32regulation of interferon-alpha production (GO:0032647)2.95758730
33Arp2/3 complex-mediated actin nucleation (GO:0034314)2.94969750
34detection of other organism (GO:0098543)2.94832264
35positive regulation of Cdc42 GTPase activity (GO:0043089)2.94477921
36JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.93646943
37type I interferon signaling pathway (GO:0060337)2.93607669
38cellular response to type I interferon (GO:0071357)2.93607669
39lipopolysaccharide-mediated signaling pathway (GO:0031663)2.91299297
40positive thymic T cell selection (GO:0045059)2.88218278
41regulation of histone H3-K27 methylation (GO:0061085)2.84106421
42interferon-gamma-mediated signaling pathway (GO:0060333)2.84087730
43apoptotic cell clearance (GO:0043277)2.83624899
44regulation of integrin activation (GO:0033623)2.82701578
45T cell apoptotic process (GO:0070231)2.82425898
46positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.82279282
47negative thymic T cell selection (GO:0045060)2.80777216
48negative regulation of granulocyte differentiation (GO:0030853)2.79752502
49signal complex assembly (GO:0007172)2.78838802
50protein localization to endosome (GO:0036010)2.78263655
51response to muramyl dipeptide (GO:0032495)2.78108566
52positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.77835128
53positive regulation of natural killer cell differentiation (GO:0032825)2.72751628
54pinocytosis (GO:0006907)2.72511603
55B cell mediated immunity (GO:0019724)2.70670210
56negative regulation of stress fiber assembly (GO:0051497)2.69361314
57negative T cell selection (GO:0043383)2.67751164
58growth hormone receptor signaling pathway (GO:0060396)2.66338051
59tolerance induction (GO:0002507)2.66174489
60regulation of leukocyte degranulation (GO:0043300)2.64977880
61positive regulation of lamellipodium assembly (GO:0010592)2.64280816
62positive regulation of lamellipodium organization (GO:1902745)2.62647272
63response to host (GO:0075136)2.61628197
64response to host defenses (GO:0052200)2.61628197
65response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.61628197
66regulation of early endosome to late endosome transport (GO:2000641)2.61602398
67positive regulation of T cell apoptotic process (GO:0070234)2.61492997
68regulation of mast cell degranulation (GO:0043304)2.59986242
69negative regulation of erythrocyte differentiation (GO:0045647)2.58722607
70regulation of ARF GTPase activity (GO:0032312)2.58174369
71regulation of extracellular matrix disassembly (GO:0010715)2.56990555
72positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.56958717
73myeloid dendritic cell differentiation (GO:0043011)2.56833361
74regulation of T cell tolerance induction (GO:0002664)2.56769336
75response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.56451887
76response to host immune response (GO:0052572)2.56451887
77regulation of NFAT protein import into nucleus (GO:0051532)2.56437670
78thymic T cell selection (GO:0045061)2.54241227
79Golgi transport vesicle coating (GO:0048200)2.53735295
80COPI coating of Golgi vesicle (GO:0048205)2.53735295
81regulation of dendritic cell antigen processing and presentation (GO:0002604)2.53333671
82barbed-end actin filament capping (GO:0051016)2.53324499
83positive regulation of B cell differentiation (GO:0045579)2.51119043
84regulation of T-helper 2 cell differentiation (GO:0045628)2.51033343
85stress fiber assembly (GO:0043149)2.50599268
86mannose metabolic process (GO:0006013)2.49030111
87natural killer cell differentiation (GO:0001779)2.48802851
88modulation by virus of host process (GO:0019054)2.48649526
89response to laminar fluid shear stress (GO:0034616)2.47426703
90lymphocyte apoptotic process (GO:0070227)2.47418273
91negative regulation of cytokine production involved in immune response (GO:0002719)2.47068257
92regulation of myeloid leukocyte mediated immunity (GO:0002886)2.46735492
93detection of external biotic stimulus (GO:0098581)2.46393314
94positive regulation of protein deacetylation (GO:0090312)2.46071947
95negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.45117717
96positive T cell selection (GO:0043368)2.44484196
97positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.44458259
98response to interferon-alpha (GO:0035455)2.43972127
99myeloid cell activation involved in immune response (GO:0002275)2.43823399
100negative regulation of phagocytosis (GO:0050765)2.43510280
101modulation by symbiont of host cellular process (GO:0044068)2.43496127
102activation of JUN kinase activity (GO:0007257)2.43454819
103leukocyte cell-cell adhesion (GO:0007159)2.42896727
104positive regulation of gene expression, epigenetic (GO:0045815)2.42482854
105myeloid dendritic cell activation (GO:0001773)2.41804880
106positive regulation of blood vessel endothelial cell migration (GO:0043536)2.41049010
107leukocyte aggregation (GO:0070486)2.40457850
108negative regulation of interleukin-12 production (GO:0032695)2.40001511
109regulation of mononuclear cell migration (GO:0071675)2.39660490
110actin nucleation (GO:0045010)2.39204382
111NLS-bearing protein import into nucleus (GO:0006607)2.38230519
112negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.38140855
113embryonic process involved in female pregnancy (GO:0060136)2.38131063
114positive regulation of isotype switching (GO:0045830)2.36957818
115negative regulation of viral release from host cell (GO:1902187)2.36683445
116positive regulation of cell adhesion mediated by integrin (GO:0033630)2.36170869
117negative regulation of leukocyte mediated immunity (GO:0002704)2.35917952
118regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.35356306
119B cell receptor signaling pathway (GO:0050853)2.34774290
120negative regulation of innate immune response (GO:0045824)2.34745073
121positive regulation of interferon-beta production (GO:0032728)2.34398788
122regulation of B cell differentiation (GO:0045577)2.34247755
123regulation of response to interferon-gamma (GO:0060330)2.33724964
124activation of Rac GTPase activity (GO:0032863)2.33627916
125apoptotic process involved in morphogenesis (GO:0060561)2.33244446
126T cell migration (GO:0072678)2.33243081
127cell-substrate junction assembly (GO:0007044)2.32844745
128regulation of interleukin-2 biosynthetic process (GO:0045076)2.31822765
129respiratory burst (GO:0045730)2.31340904
130regulation of necrotic cell death (GO:0010939)2.31060545
131natural killer cell mediated immunity (GO:0002228)2.30702534
132natural killer cell mediated cytotoxicity (GO:0042267)2.30702534
133regulation of necroptotic process (GO:0060544)2.28132316
134regulation of defense response to virus by virus (GO:0050690)2.28097924
135focal adhesion assembly (GO:0048041)2.27610927
136cell-substrate adherens junction assembly (GO:0007045)2.27610927
137T cell selection (GO:0045058)2.27434081
138activation of MAPKKK activity (GO:0000185)2.27357940
139intracellular estrogen receptor signaling pathway (GO:0030520)2.27338041
140regulation of cholesterol storage (GO:0010885)2.27074260
141regulation of tolerance induction (GO:0002643)2.27064406
142endothelial tube morphogenesis (GO:0061154)2.26826718
143morphogenesis of an endothelium (GO:0003159)2.26826718
144regulation of mast cell activation involved in immune response (GO:0033006)2.26589111
145positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.26387620
1463-UTR-mediated mRNA stabilization (GO:0070935)2.25987120

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EGR1_19374776_ChIP-ChIP_THP-1_Human4.02488295
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.69241865
3E2F7_22180533_ChIP-Seq_HELA_Human3.49669288
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.38710818
5MYC_22102868_ChIP-Seq_BL_Human3.29829559
6IRF8_21731497_ChIP-ChIP_J774_Mouse3.22662532
7* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.94395255
8VDR_21846776_ChIP-Seq_THP-1_Human2.64630412
9STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.58827063
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.54584682
11MYB_21317192_ChIP-Seq_ERMYB_Mouse2.39189135
12SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.36270334
13* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.35855646
14TCF7_22412390_ChIP-Seq_EML_Mouse2.30046608
15IRF8_27001747_Chip-Seq_BMDM_Mouse2.27448078
16IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.22983630
17FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.16358073
18BP1_19119308_ChIP-ChIP_Hs578T_Human2.14356422
19FOXM1_23109430_ChIP-Seq_U2OS_Human2.08289985
20* MAF_26560356_Chip-Seq_TH1_Human2.02612115
21ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.00789161
22* ELK3_25401928_ChIP-Seq_HUVEC_Human1.99940842
23KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.99666992
24KDM2B_26808549_Chip-Seq_DND41_Human1.98133456
25SCL_19346495_ChIP-Seq_HPC-7_Human1.96487018
26VDR_24763502_ChIP-Seq_THP-1_Human1.96318069
27UTX_26944678_Chip-Seq_JUKART_Human1.92932102
28NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.89722984
29KDM2B_26808549_Chip-Seq_SUP-B15_Human1.89673471
30IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.87050107
31MYB_26560356_Chip-Seq_TH2_Human1.86955576
32* SPI1_23127762_ChIP-Seq_K562_Human1.86693018
33BRD4_27068464_Chip-Seq_AML-cells_Mouse1.86672783
34KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.84857085
35SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.82750711
36RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.81507528
37E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.76743702
38STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.75429080
39RUNX1_22412390_ChIP-Seq_EML_Mouse1.72196217
40* MYB_26560356_Chip-Seq_TH1_Human1.69997569
41* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.67826580
42FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.67251503
43* SPI1_23547873_ChIP-Seq_NB4_Human1.67021533
44STAT6_21828071_ChIP-Seq_BEAS2B_Human1.65327270
45* KDM2B_26808549_Chip-Seq_K562_Human1.59409731
46* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56075055
47STAT4_19710469_ChIP-ChIP_TH1__Mouse1.53707113
48CTCF_27219007_Chip-Seq_ERYTHROID_Human1.52102813
49Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.48371327
50* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.45184550
51TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45160373
52SA1_27219007_Chip-Seq_ERYTHROID_Human1.44641669
53RUNX_20019798_ChIP-Seq_JUKART_Human1.42988662
54P68_20966046_ChIP-Seq_HELA_Human1.42278440
55TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.42243310
56EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.40401381
57PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.37675598
58LXR_22292898_ChIP-Seq_THP-1_Human1.37611483
59THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.35229586
60MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.33980312
61KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.33493184
62* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.33218052
63EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.33069769
64* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.32405174
65SMC4_20622854_ChIP-Seq_HELA_Human1.31817549
66TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.28745466
67TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.28319836
68TFEB_21752829_ChIP-Seq_HELA_Human1.28266927
69* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.26753573
70BCOR_27268052_Chip-Seq_Bcells_Human1.26612695
71* ATF3_27146783_Chip-Seq_COLON_Human1.24678964
72TET1_21451524_ChIP-Seq_MESCs_Mouse1.24237675
73* MAF_26560356_Chip-Seq_TH2_Human1.23877977
74RACK7_27058665_Chip-Seq_MCF-7_Human1.23518448
75ESR2_21235772_ChIP-Seq_MCF-7_Human1.22351236
76PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.21843171
77NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.21255472
78CIITA_25753668_ChIP-Seq_RAJI_Human1.21032725
79BCL6_27268052_Chip-Seq_Bcells_Human1.19375968
80KDM2B_26808549_Chip-Seq_JURKAT_Human1.18959613
81* NCOR1_26117541_ChIP-Seq_K562_Human1.15916570
82GATA3_27048872_Chip-Seq_THYMUS_Human1.14059129
83VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.14013016
84SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13325485
85KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.11140670
86ZFP281_18757296_ChIP-ChIP_E14_Mouse1.11019792
87RARG_19884340_ChIP-ChIP_MEFs_Mouse1.10210751
88CREB1_26743006_Chip-Seq_LNCaP_Human1.09595384
89SRY_22984422_ChIP-ChIP_TESTIS_Rat1.08784324
90CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.08758196
91GATA1_19941827_ChIP-Seq_MEL_Mouse1.08742262
92SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.07934039
93GATA1_22383799_ChIP-Seq_G1ME_Mouse1.07898778
94* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.07670865
95* PU_27001747_Chip-Seq_BMDM_Mouse1.06008823
96PU.1_20513432_ChIP-Seq_Bcells_Mouse1.05783722
97FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.05612032
98PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05085931
99TP63_17297297_ChIP-ChIP_HaCaT_Human1.03956288
100CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.02025000
101RUNX1_27514584_Chip-Seq_MCF-7_Human1.01699435
102CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.01588989
103KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.01054756
104TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00768269
105CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00601159
106GATA2_22383799_ChIP-Seq_G1ME_Mouse0.99668596
107TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.98590537
108CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.98479056
109SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.98281348
110ZNF263_19887448_ChIP-Seq_K562_Human0.98118125
111HIF1A_21447827_ChIP-Seq_MCF-7_Human0.97920708
112* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95269172
113DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.94141607
114ELF1_20517297_ChIP-Seq_JURKAT_Human0.93729261
115* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93713434
116ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93478461
117FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.92352824
118LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.92234842
119STAT3_1855785_ChIP-Seq_MESCs_Mouse0.91503805
120GATA1_19941826_ChIP-Seq_K562_Human0.91485324
121PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91096392
122GATA2_21666600_ChIP-Seq_HMVEC_Human0.88692974
123E2F1_21310950_ChIP-Seq_MCF-7_Human0.88255597
124CLOCK_20551151_ChIP-Seq_293T_Human0.88236319
125CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88193749
126CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88031241
127FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.86843178
128DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.86615943

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003436_decreased_susceptibility_to2.96074843
2MP0000685_abnormal_immune_system2.93801157
3MP0003303_peritoneal_inflammation2.83021602
4MP0005451_abnormal_body_composition2.81891476
5MP0003705_abnormal_hypodermis_morpholog2.80631628
6MP0003300_gastrointestinal_ulcer2.74247710
7MP0001835_abnormal_antigen_presentation2.62861183
8MP0010352_gastrointestinal_tract_polyps2.59118329
9MP0004510_myositis2.43806158
10MP0005387_immune_system_phenotype2.29425237
11MP0001790_abnormal_immune_system2.29425237
12MP0005076_abnormal_cell_differentiation2.23318407
13MP0008260_abnormal_autophagy2.20008326
14MP0003172_abnormal_lysosome_physiology2.19355154
15MP0005058_abnormal_lysosome_morphology2.16067208
16MP0003566_abnormal_cell_adhesion2.13170015
17MP0000569_abnormal_digit_pigmentation2.07582809
18MP0009278_abnormal_bone_marrow2.06370045
19MP0005000_abnormal_immune_tolerance2.06005614
20MP0001800_abnormal_humoral_immune2.05611164
21MP0010307_abnormal_tumor_latency2.03157970
22MP0002452_abnormal_antigen_presenting2.02795353
23MP0002419_abnormal_innate_immunity1.94216836
24MP0003191_abnormal_cellular_cholesterol1.92638185
25MP0004808_abnormal_hematopoietic_stem1.91553124
26MP0002723_abnormal_immune_serum1.84635385
27MP0002396_abnormal_hematopoietic_system1.83806337
28MP0005025_abnormal_response_to1.83487176
29MP0001545_abnormal_hematopoietic_system1.81413180
30MP0005397_hematopoietic_system_phenotyp1.81413180
31MP0002405_respiratory_system_inflammati1.80001607
32MP0001819_abnormal_immune_cell1.78447165
33MP0002420_abnormal_adaptive_immunity1.78294641
34MP0002398_abnormal_bone_marrow1.77174726
35MP0005671_abnormal_response_to1.75202460
36MP0003763_abnormal_thymus_physiology1.73763055
37MP0004947_skin_inflammation1.72266600
38MP0009785_altered_susceptibility_to1.70236395
39MP0006082_CNS_inflammation1.67689202
40MP0005464_abnormal_platelet_physiology1.64402022
41MP0003091_abnormal_cell_migration1.62430990
42MP0009333_abnormal_splenocyte_physiolog1.58944619
43MP0001533_abnormal_skeleton_physiology1.58193215
44MP0005023_abnormal_wound_healing1.55598570
45MP0000716_abnormal_immune_system1.54053649
46MP0000689_abnormal_spleen_morphology1.53543842
47MP0008961_abnormal_basal_metabolism1.52156257
48MP0010155_abnormal_intestine_physiology1.50146941
49MP0000678_abnormal_parathyroid_gland1.46981984
50MP0002722_abnormal_immune_system1.46033849
51MP0003448_altered_tumor_morphology1.43368597
52MP0009840_abnormal_foam_cell1.43098827
53MP0004381_abnormal_hair_follicle1.42718070
54MP0002148_abnormal_hypersensitivity_rea1.41808891
55MP0005310_abnormal_salivary_gland1.38949929
56MP0000858_altered_metastatic_potential1.37518197
57MP0000703_abnormal_thymus_morphology1.37175617
58MP0002429_abnormal_blood_cell1.35341442
59MP0000490_abnormal_crypts_of1.34634569
60MP0001849_ear_inflammation1.30688114
61MP0002166_altered_tumor_susceptibility1.29478992
62MP0001845_abnormal_inflammatory_respons1.27056827
63MP0001915_intracranial_hemorrhage1.25763404
64MP0001958_emphysema1.23849582
65MP0002877_abnormal_melanocyte_morpholog1.23649784
66MP0005409_darkened_coat_color1.22933951
67MP0003279_aneurysm1.21430758
68MP0000465_gastrointestinal_hemorrhage1.16717707
69MP0000733_abnormal_muscle_development1.15076588
70MP0005257_abnormal_intraocular_pressure1.13653913
71MP0008438_abnormal_cutaneous_collagen1.13374096
72MP0001873_stomach_inflammation1.12447463
73MP0003183_abnormal_peptide_metabolism1.11410920
74MP0003828_pulmonary_edema1.10392289
75MP0000343_altered_response_to1.10169074
76MP0002006_tumorigenesis1.09722966
77MP0003866_abnormal_defecation1.08047238
78MP0002933_joint_inflammation1.06514465
79MP0001348_abnormal_lacrimal_gland1.06054766
80MP0002998_abnormal_bone_remodeling1.02696879
81MP0001851_eye_inflammation1.02335802
82MP0003077_abnormal_cell_cycle0.99776003
83MP0001853_heart_inflammation0.98912156
84MP0000767_abnormal_smooth_muscle0.98876844
85MP0002019_abnormal_tumor_incidence0.98191192
86MP0002796_impaired_skin_barrier0.96737512
87MP0005666_abnormal_adipose_tissue0.96482900
88MP0005390_skeleton_phenotype0.96329233
89MP0005621_abnormal_cell_physiology0.95604535
90MP0002060_abnormal_skin_morphology0.95538487
91MP0010234_abnormal_vibrissa_follicle0.95361549
92MP0004264_abnormal_extraembryonic_tissu0.93856577
93MP0006054_spinal_hemorrhage0.93267709
94MP0008007_abnormal_cellular_replicative0.91875646
95MP0000350_abnormal_cell_proliferation0.91451436
96MP0003045_fibrosis0.91398261
97MP0005375_adipose_tissue_phenotype0.91168299
98MP0008469_abnormal_protein_level0.90989335
99MP0003111_abnormal_nucleus_morphology0.89718633
100MP0001730_embryonic_growth_arrest0.89487554
101MP0003693_abnormal_embryo_hatching0.89173130
102MP0000015_abnormal_ear_pigmentation0.87623691
103MP0004185_abnormal_adipocyte_glucose0.85809795
104MP0005166_decreased_susceptibility_to0.84842510
105MP0003656_abnormal_erythrocyte_physiolo0.81376234
106MP0000604_amyloidosis0.80646945
107MP0003724_increased_susceptibility_to0.79772472
108MP0009931_abnormal_skin_appearance0.79705602
109MP0003453_abnormal_keratinocyte_physiol0.79696346
110MP0002132_abnormal_respiratory_system0.79553712
111MP0000313_abnormal_cell_death0.77878029
112MP0003075_altered_response_to0.76100712
113MP0003795_abnormal_bone_structure0.75832175
114MP0003984_embryonic_growth_retardation0.75148109
115MP0002086_abnormal_extraembryonic_tissu0.74773449
116MP0002254_reproductive_system_inflammat0.74676417
117MP0001216_abnormal_epidermal_layer0.73977543
118MP0000249_abnormal_blood_vessel0.73948059
119MP0005164_abnormal_response_to0.73858747
120MP0002088_abnormal_embryonic_growth/wei0.73113571
121MP0004233_abnormal_muscle_weight0.71779102
122MP0004957_abnormal_blastocyst_morpholog0.68458293
123MP0005384_cellular_phenotype0.68405453
124MP0004858_abnormal_nervous_system0.68343832

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)3.98977820
2Recurrent abscess formation (HP:0002722)3.52501549
3Autoimmune thrombocytopenia (HP:0001973)3.30224491
4Increased cerebral lipofuscin (HP:0011813)3.10188186
5Elevated erythrocyte sedimentation rate (HP:0003565)3.04913407
6Myositis (HP:0100614)3.01599949
7Abnormality of the fingertips (HP:0001211)3.00047507
8Cerebral aneurysm (HP:0004944)2.96883833
9Recurrent bacterial skin infections (HP:0005406)2.93769682
10Cellulitis (HP:0100658)2.89118707
11Increased density of long bones (HP:0006392)2.79443852
12Recurrent fungal infections (HP:0002841)2.77950385
13Nasal polyposis (HP:0100582)2.77477601
14Increased connective tissue (HP:0009025)2.74429280
15Spondylolisthesis (HP:0003302)2.69386959
16Broad face (HP:0000283)2.68541192
17Protrusio acetabuli (HP:0003179)2.66026515
18Recurrent viral infections (HP:0004429)2.65999855
19Obstructive sleep apnea (HP:0002870)2.65416233
20Distal lower limb amyotrophy (HP:0008944)2.64111702
21Dysostosis multiplex (HP:0000943)2.61767447
22Chronic otitis media (HP:0000389)2.61318346
23Abnormality of the nasal mucosa (HP:0000433)2.53501144
24Peritonitis (HP:0002586)2.51416022
25Hypertensive crisis (HP:0100735)2.43151121
26Cervical subluxation (HP:0003308)2.42862887
27Cholecystitis (HP:0001082)2.42254450
28Abnormal gallbladder physiology (HP:0012438)2.42254450
29Obstructive lung disease (HP:0006536)2.41463930
30Chronic obstructive pulmonary disease (HP:0006510)2.41463930
31Recurrent gram-negative bacterial infections (HP:0005420)2.41128499
32Interstitial pulmonary disease (HP:0006530)2.39724307
33Orchitis (HP:0100796)2.39477038
34Increased neuronal autofluorescent lipopigment (HP:0002074)2.36988946
35Abnormality of polysaccharide metabolism (HP:0011012)2.36891368
36Abnormality of glycosaminoglycan metabolism (HP:0004371)2.36891368
37Abnormality of mucopolysaccharide metabolism (HP:0011020)2.36891368
38Shallow orbits (HP:0000586)2.36667940
39Mediastinal lymphadenopathy (HP:0100721)2.36582421
40Vacuolated lymphocytes (HP:0001922)2.35091355
41Urinary glycosaminoglycan excretion (HP:0003541)2.32834183
42Mucopolysacchariduria (HP:0008155)2.32834183
43Aortic aneurysm (HP:0004942)2.32225978
44Premature rupture of membranes (HP:0001788)2.30991338
45Recurrent bronchitis (HP:0002837)2.29880189
46Spontaneous hematomas (HP:0007420)2.29248428
47Abnormality of macrophages (HP:0004311)2.23253294
48Aneurysm (HP:0002617)2.21797281
49Polycythemia (HP:0001901)2.21468877
50Emphysema (HP:0002097)2.20769987
51Vertebral compression fractures (HP:0002953)2.19499081
52Thin bony cortex (HP:0002753)2.18426612
53Fatigue (HP:0012378)2.18399281
54Hyperacusis (HP:0010780)2.16808536
55Stridor (HP:0010307)2.14967966
56Segmental peripheral demyelination/remyelination (HP:0003481)2.14717982
57Pustule (HP:0200039)2.13575688
58Genu recurvatum (HP:0002816)2.13335483
59Hematochezia (HP:0002573)2.12506055
60Slow saccadic eye movements (HP:0000514)2.10380778
61Periodontitis (HP:0000704)2.09964397
62Leukocytosis (HP:0001974)2.08444749
63Dilatation of the ascending aorta (HP:0005111)2.06370177
64Chest pain (HP:0100749)2.05545904
65Thrombocytosis (HP:0001894)2.03106216
66Striae distensae (HP:0001065)2.01738946
67Malnutrition (HP:0004395)2.01191060
68Polygenic inheritance (HP:0010982)2.01157208
69Gastrointestinal dysmotility (HP:0002579)2.00749438
70Distal upper limb amyotrophy (HP:0007149)1.99862690
71Upper limb amyotrophy (HP:0009129)1.99862690
72Hemorrhage of the eye (HP:0011885)1.98801151
73Arterial thrombosis (HP:0004420)1.97545929
74Seborrheic dermatitis (HP:0001051)1.97242142
75Centrally nucleated skeletal muscle fibers (HP:0003687)1.97130524
76Myocardial infarction (HP:0001658)1.93924338
77Frequent falls (HP:0002359)1.93054964
78Vasculitis (HP:0002633)1.92919488
79Agnosia (HP:0010524)1.91900374
80Hand muscle atrophy (HP:0009130)1.91426682
81J-shaped sella turcica (HP:0002680)1.90999693
82Gastrointestinal inflammation (HP:0004386)1.90989917
83Hypertriglyceridemia (HP:0002155)1.90519695
84Truncus arteriosus (HP:0001660)1.90288530
85Supranuclear gaze palsy (HP:0000605)1.87518451
86Long palpebral fissure (HP:0000637)1.87319176
87Achilles tendon contracture (HP:0001771)1.87240569
88Ankyloglossia (HP:0010296)1.87095975
89Distal lower limb muscle weakness (HP:0009053)1.86909115
90Bowel incontinence (HP:0002607)1.86267778
91Easy fatigability (HP:0003388)1.86180765
92Petechiae (HP:0000967)1.86060828
93Gingivitis (HP:0000230)1.86023938
94Osteomyelitis (HP:0002754)1.86014988
95Nuclear cataract (HP:0100018)1.85692314
96Fragile skin (HP:0001030)1.85654430
97Abnormality of glycolipid metabolism (HP:0010969)1.84967336
98Abnormality of liposaccharide metabolism (HP:0010968)1.84967336
99Abnormality of glycosphingolipid metabolism (HP:0004343)1.84967336
100Abnormality of the thoracic spine (HP:0100711)1.84907735
101Long eyelashes (HP:0000527)1.84010655
102Atelectasis (HP:0100750)1.83323929
103Narrow palate (HP:0000189)1.83092886
104Disinhibition (HP:0000734)1.80242132
105Ankle contracture (HP:0006466)1.79556224
106Aortic dissection (HP:0002647)1.79250722
107Abnormal large intestine physiology (HP:0012700)1.78822946
108Increased serum ferritin (HP:0003281)1.78637693
109Inflammation of the large intestine (HP:0002037)1.78146039
110Mitral valve prolapse (HP:0001634)1.77260632
111Long toe (HP:0010511)1.77193461
112Abnormality of oral frenula (HP:0000190)1.76638039
113Colitis (HP:0002583)1.76475981
114Gastrointestinal stroma tumor (HP:0100723)1.76206353
115Increased IgE level (HP:0003212)1.75821466
116Radial bowing (HP:0002986)1.75812783
117Axonal loss (HP:0003447)1.75723577
118Trigonocephaly (HP:0000243)1.75191977
119Retrobulbar optic neuritis (HP:0100654)1.74612392
120Optic neuritis (HP:0100653)1.74612392
121Peripheral hypomyelination (HP:0007182)1.74446986
122Meningitis (HP:0001287)1.74322339
123Systemic lupus erythematosus (HP:0002725)1.73716470
124Recurrent skin infections (HP:0001581)1.73640102
125T lymphocytopenia (HP:0005403)1.73569119
126Purpura (HP:0000979)1.73518212
127Ulnar bowing (HP:0003031)1.72927209
128Increased variability in muscle fiber diameter (HP:0003557)1.72723049
129Osteolytic defects of the phalanges of the hand (HP:0009771)1.72216800
130Osteolytic defects of the hand bones (HP:0009699)1.72216800
131Epistaxis (HP:0000421)1.72205552
132IgM deficiency (HP:0002850)1.71867824
133Abnormality of T cell number (HP:0011839)1.71492483
134Disproportionate tall stature (HP:0001519)1.71487062
135Urethral obstruction (HP:0000796)1.69035899
136Arterial tortuosity (HP:0005116)1.68240143
137Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.66969436
138Pulmonary infiltrates (HP:0002113)1.66770162
139Asymmetric septal hypertrophy (HP:0001670)1.66330594
140Abnormality of T cells (HP:0002843)1.66286557
141Biconcave vertebral bodies (HP:0004586)1.66048106
142High pitched voice (HP:0001620)1.63754054
143Abnormality of the peritoneum (HP:0002585)1.63433617
144Prolonged bleeding time (HP:0003010)1.61727940
145Loss of speech (HP:0002371)1.61276644
146Bicuspid aortic valve (HP:0001647)1.59869877
147Gastrointestinal infarctions (HP:0005244)1.59268050

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN13.79386595
2TRIB33.51125663
3CDK123.50717556
4PRPF4B3.05691424
5MAP4K12.99518221
6EEF2K2.78036956
7PKN22.63862337
8MAP3K102.53401872
9TAOK32.38274538
10IRAK32.14081953
11SMG12.05872294
12JAK32.04332401
13TYK22.02805081
14STK102.00773793
15TBK11.94658919
16MAPKAPK31.89507836
17KIT1.77909800
18RPS6KA41.72487830
19TAOK11.66073513
20TTN1.63190843
21RIPK11.51642555
22ZAP701.48981248
23CDC42BPA1.46315349
24BMX1.38607312
25TAOK21.34784744
26EPHB11.32606692
27CHUK1.32097168
28SIK21.27804092
29PTK61.25338522
30PRKD21.23753071
31JAK11.23619667
32MARK21.23537166
33NME21.22701919
34FGFR41.21898737
35BLK1.20959910
36MAP3K131.19379881
37IKBKE1.19147631
38NEK21.17163150
39LRRK21.15444963
40EPHA21.09853066
41TNK21.08048103
42MAP3K141.07223815
43CAMK1D1.06638873
44HCK1.06443325
45MST1R1.05215595
46MOS0.99277913
47DDR20.98162744
48PAK40.97300890
49EPHA30.95050992
50GRK60.94334739
51MAP3K60.93666311
52SIK10.92483928
53MAP3K70.92211927
54CSF1R0.92123501
55DMPK0.91682263
56CAMK1G0.89277803
57FLT30.88537357
58FGFR30.88280057
59BTK0.86612386
60MTOR0.86458164
61MAP3K80.86347725
62ICK0.86105763
63CSK0.85231530
64PDPK10.85173154
65KSR20.84907146
66TGFBR20.83546218
67RIPK40.83233132
68IKBKB0.82013491
69MAP2K30.80934506
70PIM20.80664010
71CDC70.80610643
72MAP3K30.78142265
73MAP3K20.77432731
74TXK0.77328907
75SYK0.76200008
76PTK20.76119012
77TESK20.75796615
78TESK10.75779035
79PIM10.75341550
80STK380.74600448
81ARAF0.73615214
82PDGFRA0.72268193
83BRD40.72064595
84CDK60.71217978
85SIK30.70989327
86KDR0.70551761
87NEK90.70401748
88TRPM70.69623128
89RET0.68964071
90LATS10.68696277
91LCK0.67987896
92CLK10.67844675
93DAPK10.67122490
94PDK10.67000440
95STK30.66618183
96MAP3K110.65437151
97JAK20.65078669
98PDGFRB0.64497199
99HIPK20.64045910
100MAP3K90.63867126
101CDK90.61342197
102LATS20.60676092
103MAP3K10.59875685
104TYRO30.59155002
105CDK70.57061538
106CDK40.56616667
107LMTK20.56582925
108MAPK120.56577621
109NLK0.56487229
110MATK0.54437959
111RPS6KA20.54397807
112PRKG20.53828094
113MAPKAPK20.53770787
114MAPK70.53307117
115SCYL20.52853632
116PRKCH0.52778249
117IRAK20.51401183
118FGR0.51070691
119ALK0.50909648
120RPS6KC10.50605796
121RPS6KL10.50605796
122ITK0.50434848
123EGFR0.49898100
124PRKD30.49335408
125IRAK40.49024762
126TGFBR10.48695710
127PAK20.47028588
128MARK30.44985958
129LYN0.41866459
130MAPK110.41489714
131MAP2K60.41052524
132FES0.40907004
133PTK2B0.40290070

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051402.26335897
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.13900111
3Osteoclast differentiation_Homo sapiens_hsa043802.07961779
4B cell receptor signaling pathway_Homo sapiens_hsa046621.97264713
5Chronic myeloid leukemia_Homo sapiens_hsa052201.82408005
6Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.80185734
7NF-kappa B signaling pathway_Homo sapiens_hsa040641.77936174
8Measles_Homo sapiens_hsa051621.75624542
9Shigellosis_Homo sapiens_hsa051311.74292711
10Acute myeloid leukemia_Homo sapiens_hsa052211.63561414
11Toll-like receptor signaling pathway_Homo sapiens_hsa046201.62097408
12Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.58660597
13Toxoplasmosis_Homo sapiens_hsa051451.55135682
14Glycosaminoglycan degradation_Homo sapiens_hsa005311.52531522
15Apoptosis_Homo sapiens_hsa042101.52310315
16Pancreatic cancer_Homo sapiens_hsa052121.51734097
17Herpes simplex infection_Homo sapiens_hsa051681.47662260
18Antigen processing and presentation_Homo sapiens_hsa046121.44013922
19Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.43280355
20Influenza A_Homo sapiens_hsa051641.43132683
21TNF signaling pathway_Homo sapiens_hsa046681.42518398
22Lysosome_Homo sapiens_hsa041421.42057113
23Tuberculosis_Homo sapiens_hsa051521.39378833
24Hepatitis B_Homo sapiens_hsa051611.38141421
25Primary immunodeficiency_Homo sapiens_hsa053401.36966041
26Legionellosis_Homo sapiens_hsa051341.35015996
27Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.35012114
28T cell receptor signaling pathway_Homo sapiens_hsa046601.33459229
29Malaria_Homo sapiens_hsa051441.31327395
30Viral myocarditis_Homo sapiens_hsa054161.29124881
31Jak-STAT signaling pathway_Homo sapiens_hsa046301.28954058
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.28745553
33Graft-versus-host disease_Homo sapiens_hsa053321.28409653
34AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.22517169
35Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.21720423
36Other glycan degradation_Homo sapiens_hsa005111.21143189
37Neurotrophin signaling pathway_Homo sapiens_hsa047221.20876172
38Leukocyte transendothelial migration_Homo sapiens_hsa046701.20344928
39Staphylococcus aureus infection_Homo sapiens_hsa051501.19978190
40Autoimmune thyroid disease_Homo sapiens_hsa053201.19735238
41Small cell lung cancer_Homo sapiens_hsa052221.19313259
42Pertussis_Homo sapiens_hsa051331.18544570
43Prolactin signaling pathway_Homo sapiens_hsa049171.18196171
44Notch signaling pathway_Homo sapiens_hsa043301.16432401
45Salmonella infection_Homo sapiens_hsa051321.14391199
46Intestinal immune network for IgA production_Homo sapiens_hsa046721.13225037
47Chemokine signaling pathway_Homo sapiens_hsa040621.12691771
48NOD-like receptor signaling pathway_Homo sapiens_hsa046211.12234131
49RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.10762807
50Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.10417523
51HTLV-I infection_Homo sapiens_hsa051661.09847402
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.08436741
53VEGF signaling pathway_Homo sapiens_hsa043701.07554918
54Colorectal cancer_Homo sapiens_hsa052101.07252423
55Adherens junction_Homo sapiens_hsa045201.06378277
56Platelet activation_Homo sapiens_hsa046111.05293333
57Proteoglycans in cancer_Homo sapiens_hsa052051.04872613
58mTOR signaling pathway_Homo sapiens_hsa041501.04842748
59Prion diseases_Homo sapiens_hsa050201.02982048
60Non-small cell lung cancer_Homo sapiens_hsa052231.02929945
61Hematopoietic cell lineage_Homo sapiens_hsa046401.02719809
62Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.97994992
63ErbB signaling pathway_Homo sapiens_hsa040120.96134995
64MicroRNAs in cancer_Homo sapiens_hsa052060.95797818
65Fructose and mannose metabolism_Homo sapiens_hsa000510.94342114
66Focal adhesion_Homo sapiens_hsa045100.91577190
67Thyroid hormone signaling pathway_Homo sapiens_hsa049190.91554876
68Amoebiasis_Homo sapiens_hsa051460.91345979
69Cell cycle_Homo sapiens_hsa041100.89884051
70Hepatitis C_Homo sapiens_hsa051600.89742226
71Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88270192
72Epstein-Barr virus infection_Homo sapiens_hsa051690.86683395
73Endometrial cancer_Homo sapiens_hsa052130.86289216
74GnRH signaling pathway_Homo sapiens_hsa049120.85610191
75Regulation of actin cytoskeleton_Homo sapiens_hsa048100.84554982
76Viral carcinogenesis_Homo sapiens_hsa052030.82251706
77Inositol phosphate metabolism_Homo sapiens_hsa005620.81835440
78p53 signaling pathway_Homo sapiens_hsa041150.81791557
79HIF-1 signaling pathway_Homo sapiens_hsa040660.81423332
80Choline metabolism in cancer_Homo sapiens_hsa052310.80097193
81Insulin signaling pathway_Homo sapiens_hsa049100.78941652
82Transcriptional misregulation in cancer_Homo sapiens_hsa052020.78684741
83Insulin resistance_Homo sapiens_hsa049310.78580512
84Bladder cancer_Homo sapiens_hsa052190.78333276
85Glioma_Homo sapiens_hsa052140.76052436
86Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.76030829
87Renal cell carcinoma_Homo sapiens_hsa052110.75593997
88African trypanosomiasis_Homo sapiens_hsa051430.75127421
89Endocytosis_Homo sapiens_hsa041440.74426592
90Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.72046035
91Thyroid cancer_Homo sapiens_hsa052160.71307192
92Asthma_Homo sapiens_hsa053100.69756976
93DNA replication_Homo sapiens_hsa030300.69713829
94Allograft rejection_Homo sapiens_hsa053300.68599000
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.68362333
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67518435
97Type I diabetes mellitus_Homo sapiens_hsa049400.67314130
98Phagosome_Homo sapiens_hsa041450.67043837
99Prostate cancer_Homo sapiens_hsa052150.66450946
100Base excision repair_Homo sapiens_hsa034100.65014724
101Rheumatoid arthritis_Homo sapiens_hsa053230.64576958
102Estrogen signaling pathway_Homo sapiens_hsa049150.60364408
103Galactose metabolism_Homo sapiens_hsa000520.60263259
104FoxO signaling pathway_Homo sapiens_hsa040680.60193231
105Lysine degradation_Homo sapiens_hsa003100.59675175
106Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58203406
107Pentose phosphate pathway_Homo sapiens_hsa000300.57747623
108Type II diabetes mellitus_Homo sapiens_hsa049300.57540307
109Longevity regulating pathway - mammal_Homo sapiens_hsa042110.56928190
110Dorso-ventral axis formation_Homo sapiens_hsa043200.56052185
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.55768812
112Central carbon metabolism in cancer_Homo sapiens_hsa052300.54888919
113Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.54107749
114Caffeine metabolism_Homo sapiens_hsa002320.52861553
115Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.52682832
116Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.52066045
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.50470819
118Pathways in cancer_Homo sapiens_hsa052000.49019746
119TGF-beta signaling pathway_Homo sapiens_hsa043500.48202619
120MAPK signaling pathway_Homo sapiens_hsa040100.46272169
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.44793045

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