MEDAG

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)6.86260892
2collagen fibril organization (GO:0030199)6.62935881
3cellular response to zinc ion (GO:0071294)6.45996886
4sequestering of extracellular ligand from receptor (GO:0035581)5.98912779
5cellular response to cadmium ion (GO:0071276)5.29997144
6chondrocyte proliferation (GO:0035988)5.02574281
7extracellular fibril organization (GO:0043206)4.93245886
8cell migration involved in heart development (GO:0060973)4.70957759
9fibril organization (GO:0097435)4.44801861
10regulation of integrin-mediated signaling pathway (GO:2001044)4.39638407
11collagen metabolic process (GO:0032963)4.33486402
12collagen catabolic process (GO:0030574)4.23340856
13keratan sulfate catabolic process (GO:0042340)4.19708634
14peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)4.14425384
15regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.13471745
16detection of molecule of bacterial origin (GO:0032490)4.12748406
17bone trabecula formation (GO:0060346)4.11460113
18skin morphogenesis (GO:0043589)4.08901173
19multicellular organismal macromolecule metabolic process (GO:0044259)4.06444824
20extracellular negative regulation of signal transduction (GO:1900116)4.00568268
21extracellular regulation of signal transduction (GO:1900115)4.00568268
22dermatan sulfate biosynthetic process (GO:0030208)3.96290411
23extracellular matrix assembly (GO:0085029)3.93294604
24mesenchymal-epithelial cell signaling (GO:0060638)3.93026097
25blood vessel maturation (GO:0001955)3.89910314
26endothelium development (GO:0003158)3.86320236
27multicellular organismal catabolic process (GO:0044243)3.84806821
28type B pancreatic cell proliferation (GO:0044342)3.84490384
29multicellular organismal metabolic process (GO:0044236)3.84433680
30endodermal cell differentiation (GO:0035987)3.84035594
31lung vasculature development (GO:0060426)3.80029116
32regulation of metalloenzyme activity (GO:0048552)3.79744485
33neuron projection extension involved in neuron projection guidance (GO:1902284)3.76865779
34axon extension involved in axon guidance (GO:0048846)3.76865779
35dermatan sulfate metabolic process (GO:0030205)3.74641848
36regulation of cell migration involved in sprouting angiogenesis (GO:0090049)3.72553199
37positive regulation of blood vessel endothelial cell migration (GO:0043536)3.63820196
38negative regulation of smooth muscle cell migration (GO:0014912)3.62201566
39cell proliferation involved in metanephros development (GO:0072203)3.59233152
40regulation of extracellular matrix disassembly (GO:0010715)3.54887158
41ovulation from ovarian follicle (GO:0001542)3.50936645
42positive regulation of extracellular matrix organization (GO:1903055)3.50065918
43cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.47136321
44UDP-N-acetylglucosamine metabolic process (GO:0006047)3.46127335
45metanephric mesenchyme development (GO:0072075)3.40624417
46wound healing, spreading of epidermal cells (GO:0035313)3.40594683
47retina vasculature morphogenesis in camera-type eye (GO:0061299)3.40382797
48positive regulation of astrocyte differentiation (GO:0048711)3.39618683
49extracellular matrix disassembly (GO:0022617)3.39385163
50regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.22461717
51regulation of membrane protein ectodomain proteolysis (GO:0051043)3.18820243
52vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.18384666
53endocrine hormone secretion (GO:0060986)3.18310641
54negative regulation of leukocyte chemotaxis (GO:0002689)3.17743443
55cellular response to interferon-alpha (GO:0035457)3.17468470
56regulation of fibroblast migration (GO:0010762)3.17026944
57positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.16661566
58hyaluronan catabolic process (GO:0030214)3.09829602
59regulation of branching involved in salivary gland morphogenesis (GO:0060693)3.07023491
60platelet-derived growth factor receptor signaling pathway (GO:0048008)3.06352113
61regulation of plasminogen activation (GO:0010755)3.06025327
62positive regulation of macrophage activation (GO:0043032)3.04159449
63positive regulation of metanephros development (GO:0072216)3.03319209
64positive regulation of natural killer cell differentiation (GO:0032825)3.00635383
65relaxation of smooth muscle (GO:0044557)2.99064197
66positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.96496619
67extracellular matrix organization (GO:0030198)2.96170826
68negative regulation of chondrocyte differentiation (GO:0032331)2.95522054
69plasma membrane repair (GO:0001778)2.95514999
70peptidyl-proline hydroxylation (GO:0019511)2.95303355
71glomerular basement membrane development (GO:0032836)2.94851917
72extracellular structure organization (GO:0043062)2.94570373
73Notch signaling involved in heart development (GO:0061314)2.93876684
74kidney mesenchyme development (GO:0072074)2.93500788
75regulation of chemokine-mediated signaling pathway (GO:0070099)2.93024934
76regulation of endothelial cell apoptotic process (GO:2000351)2.90979364
77positive regulation of p38MAPK cascade (GO:1900745)2.90720422
78regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.90312754
79cell proliferation involved in kidney development (GO:0072111)2.89437387
80apoptotic cell clearance (GO:0043277)2.87687726
81negative regulation of focal adhesion assembly (GO:0051895)2.84350387
82negative regulation of cell junction assembly (GO:1901889)2.84350387
83negative regulation of adherens junction organization (GO:1903392)2.84350387
84negative regulation of endothelial cell apoptotic process (GO:2000352)2.83412305
85chondrocyte development (GO:0002063)2.82609402
86negative regulation of homotypic cell-cell adhesion (GO:0034111)2.79856917
87regulation of vitamin D biosynthetic process (GO:0060556)2.78449314
88cellular response to vitamin (GO:0071295)2.76335879
89regulation of apoptotic process involved in morphogenesis (GO:1902337)2.75706477
90barbed-end actin filament capping (GO:0051016)2.74278140
91negative regulation of platelet activation (GO:0010544)2.73759300
92negative chemotaxis (GO:0050919)2.73720499
93positive regulation vascular endothelial growth factor production (GO:0010575)2.72994257
94middle ear morphogenesis (GO:0042474)2.72514737
95regulation of macrophage cytokine production (GO:0010935)2.72279122
96endothelial cell morphogenesis (GO:0001886)2.72099399
97fibroblast migration (GO:0010761)2.71381144
98basement membrane organization (GO:0071711)2.71201195
99regulation of smooth muscle cell migration (GO:0014910)2.68693145
100detection of external biotic stimulus (GO:0098581)2.66469273
101protein hydroxylation (GO:0018126)2.66120304
102negative regulation of biomineral tissue development (GO:0070168)2.65690741
103positive regulation of osteoblast proliferation (GO:0033690)2.64629380
104response to gravity (GO:0009629)2.63859652
105decidualization (GO:0046697)2.62131745
106blood vessel remodeling (GO:0001974)2.61145763
107lymphangiogenesis (GO:0001946)2.59714329
108positive regulation of angiogenesis (GO:0045766)2.59008309
109iron ion import (GO:0097286)2.58668868
110glial cell migration (GO:0008347)2.58128417
111negative regulation of lipase activity (GO:0060192)2.57535662
112peptide cross-linking (GO:0018149)2.57360482
113regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.57266678
114chondroitin sulfate biosynthetic process (GO:0030206)2.56663220
115regulation of vascular endothelial growth factor production (GO:0010574)2.56223311
116response to pheromone (GO:0019236)2.55458690
117low-density lipoprotein particle clearance (GO:0034383)2.54910349
118positive regulation of endothelial cell apoptotic process (GO:2000353)2.53430659
119substrate adhesion-dependent cell spreading (GO:0034446)2.52390364
120tooth mineralization (GO:0034505)2.52281208
121negative regulation of BMP signaling pathway (GO:0030514)2.52258481
122lung lobe morphogenesis (GO:0060463)2.51983064
123smooth muscle tissue development (GO:0048745)2.51455898
124negative regulation of fatty acid transport (GO:2000192)2.49883414
125substrate-dependent cell migration (GO:0006929)2.48706287
126negative regulation of cartilage development (GO:0061037)2.48337081
127embryonic cranial skeleton morphogenesis (GO:0048701)2.47759235
128phagocytosis, recognition (GO:0006910)2.47035941
129positive regulation of macrophage cytokine production (GO:0060907)2.43211480
130protein localization to cell surface (GO:0034394)2.41768178
131negative regulation of cytosolic calcium ion concentration (GO:0051481)2.41729422
132glomerular filtration (GO:0003094)2.40168214
133opsonization (GO:0008228)2.39752632
134regulation of interleukin-8 secretion (GO:2000482)2.38487179
135virion attachment to host cell (GO:0019062)2.38475747
136adhesion of symbiont to host cell (GO:0044650)2.38475747
137venous blood vessel morphogenesis (GO:0048845)2.37643298
138regulation of tight junction assembly (GO:2000810)2.36617566
139outer ear morphogenesis (GO:0042473)2.35867724
140mesenchyme morphogenesis (GO:0072132)2.35367070
141cell adhesion mediated by integrin (GO:0033627)2.34840704
142endothelial cell proliferation (GO:0001935)2.33755273
143negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.32824309
144detection of light stimulus involved in visual perception (GO:0050908)2.31872366
145detection of light stimulus involved in sensory perception (GO:0050962)2.31872366
146detection of biotic stimulus (GO:0009595)2.30350689
147negative regulation of complement activation (GO:0045916)2.30140833
148cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.27935320
149positive regulation of fibroblast migration (GO:0010763)2.26898463
150positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.24680238
151regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.24397090
152regulation of skeletal muscle contraction (GO:0014819)2.22730932
153cellular response to amino acid stimulus (GO:0071230)2.22090243
154face morphogenesis (GO:0060325)2.21621643
155positive regulation of calcium ion import (GO:0090280)2.20700834
156regulation of transforming growth factor beta2 production (GO:0032909)2.20679281
157vascular endothelial growth factor signaling pathway (GO:0038084)2.20622003

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human5.16673296
2SMAD_19615063_ChIP-ChIP_OVARY_Human3.26211027
3HIF1A_21447827_ChIP-Seq_MCF-7_Human3.10925404
4RARG_19884340_ChIP-ChIP_MEFs_Mouse2.88293410
5GBX2_23144817_ChIP-Seq_PC3_Human2.71571364
6PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.64464951
7CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.59881472
8ESR2_21235772_ChIP-Seq_MCF-7_Human2.58754447
9CJUN_26792858_Chip-Seq_BT549_Human2.50578112
10ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.48806512
11SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.28715895
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.27917173
13NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.25868532
14CDX2_19796622_ChIP-Seq_MESCs_Mouse2.25102898
15NRF2_20460467_ChIP-Seq_MEFs_Mouse2.15188221
16NFE2L2_20460467_ChIP-Seq_MEFs_Mouse2.15188221
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.06639980
18SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.05685157
19PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.99561302
20SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.99368400
21RNF2_18974828_ChIP-Seq_MESCs_Mouse1.98761041
22EZH2_18974828_ChIP-Seq_MESCs_Mouse1.98761041
23TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.88174361
24CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.88015654
25CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.86583567
26WT1_19549856_ChIP-ChIP_CCG9911_Human1.84505299
27EP300_21415370_ChIP-Seq_HL-1_Mouse1.81913676
28KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.75836390
29KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.75836390
30KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.75836390
31SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.74433869
32TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73975941
33TP53_18474530_ChIP-ChIP_U2OS_Human1.69956577
34AR_21572438_ChIP-Seq_LNCaP_Human1.69437093
35TP63_17297297_ChIP-ChIP_HaCaT_Human1.68404305
36JARID2_20075857_ChIP-Seq_MESCs_Mouse1.68129088
37JARID2_20064375_ChIP-Seq_MESCs_Mouse1.67280629
38PIAS1_25552417_ChIP-Seq_VCAP_Human1.66716025
39ELK3_25401928_ChIP-Seq_HUVEC_Human1.66575098
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.66506713
41EZH2_27304074_Chip-Seq_ESCs_Mouse1.66155401
42STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.66088269
43FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.65317320
44TBX20_22328084_ChIP-Seq_HEART_Mouse1.60904714
45TBX20_22080862_ChIP-Seq_HEART_Mouse1.60904714
46CLOCK_20551151_ChIP-Seq_293T_Human1.57398697
47MTF2_20144788_ChIP-Seq_MESCs_Mouse1.52600145
48THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.52034684
49DROSHA_22980978_ChIP-Seq_HELA_Human1.51334484
50* BRD4_25478319_ChIP-Seq_HGPS_Human1.50326377
51RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.50056523
52RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.48751104
53RNF2_27304074_Chip-Seq_ESCs_Mouse1.46966535
54NFIB_24661679_ChIP-Seq_LUNG_Mouse1.45589135
55PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.44269082
56SMC1_22415368_ChIP-Seq_MEFs_Mouse1.40733315
57GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.40728704
58ZFP57_27257070_Chip-Seq_ESCs_Mouse1.40436498
59ZNF217_24962896_ChIP-Seq_MCF-7_Human1.40181539
60SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.38886543
61EZH2_27294783_Chip-Seq_ESCs_Mouse1.37980578
62EGR1_19374776_ChIP-ChIP_THP-1_Human1.34372729
63GATA2_21666600_ChIP-Seq_HMVEC_Human1.34296102
64Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.33621819
65SMAD4_21799915_ChIP-Seq_A2780_Human1.31407971
66TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.31000772
67SA1_22415368_ChIP-Seq_MEFs_Mouse1.25632884
68SALL4_18804426_ChIP-ChIP_XEN_Mouse1.24734052
69CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.24217673
70TP53_16413492_ChIP-PET_HCT116_Human1.23636581
71UBF1/2_26484160_Chip-Seq_HMECs_Human1.22917562
72BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.21120960
73SMC3_22415368_ChIP-Seq_MEFs_Mouse1.20019984
74VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.19329068
75TP53_20018659_ChIP-ChIP_R1E_Mouse1.18815749
76JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.18702992
77SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.18130646
78SUZ12_27294783_Chip-Seq_ESCs_Mouse1.17351920
79CTBP2_25329375_ChIP-Seq_LNCAP_Human1.17237827
80TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16858632
81JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.14873367
82TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.14540309
83POU3F2_20337985_ChIP-ChIP_501MEL_Human1.12030353
84MYB_21317192_ChIP-Seq_ERMYB_Mouse1.11073400
85SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.10919881
86NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.09146847
87P300_19829295_ChIP-Seq_ESCs_Human1.08986364
88EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.08582854
89SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.07705387
90GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06678705
91SOX9_24532713_ChIP-Seq_HFSC_Mouse1.05652644
92PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.05604557
93LXR_22158963_ChIP-Seq_LIVER_Mouse1.04613910
94RXR_22158963_ChIP-Seq_LIVER_Mouse1.03762165
95UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.02845056
96P300_27058665_Chip-Seq_ZR-75-30cells_Human1.02461083
97SOX2_20726797_ChIP-Seq_SW620_Human1.02283562
98AR_25329375_ChIP-Seq_VCAP_Human1.02100328
99SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.01154156
100SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.01154156
101SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00851328
102PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.99351425
103IKZF1_21737484_ChIP-ChIP_HCT116_Human0.99273932
104NR3C1_23031785_ChIP-Seq_PC12_Mouse0.98316749
105FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.98135978
106PPAR_26484153_Chip-Seq_NCI-H1993_Human0.97620509
107AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97409512
108OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97330967
109TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.97300336
110WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.96412697
111ER_23166858_ChIP-Seq_MCF-7_Human0.96287037
112VDR_24787735_ChIP-Seq_THP-1_Human0.96275122
113NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.95758033
114BCAT_22108803_ChIP-Seq_LS180_Human0.95704833
115ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.94762045
116SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.94060512
117CTNNB1_20460455_ChIP-Seq_HCT116_Human0.93968982
118BP1_19119308_ChIP-ChIP_Hs578T_Human0.93319256
119CBX2_27304074_Chip-Seq_ESCs_Mouse0.93173125
120AHR_22903824_ChIP-Seq_MCF-7_Human0.93069759
121ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.92876652
122TOP2B_26459242_ChIP-Seq_MCF-7_Human0.91927932
123SMAD3_21741376_ChIP-Seq_HESCs_Human0.91909070
124SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.91840971
125TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91762641
126RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.91539422
127HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.90847679
128FOXO3_23340844_ChIP-Seq_DLD1_Human0.90508123
129RXR_22108803_ChIP-Seq_LS180_Human0.90124405
130ESR1_21235772_ChIP-Seq_MCF-7_Human0.90043382
131STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.90011728
132P63_26484246_Chip-Seq_KERATINOCYTES_Human0.89485520
133MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.88356061
134SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.87610351
135KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.87152219
136WT1_25993318_ChIP-Seq_PODOCYTE_Human0.84894722
137KDM2B_26808549_Chip-Seq_K562_Human0.82197679
138ATF3_27146783_Chip-Seq_COLON_Human0.81866522
139TP53_23651856_ChIP-Seq_MEFs_Mouse0.80580689
140HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.79473016
141ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.79395528

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen9.81878962
2MP0005275_abnormal_skin_tensile6.43677615
3MP0005503_abnormal_tendon_morphology6.32009188
4MP0003279_aneurysm3.65211703
5MP0001958_emphysema3.38254031
6MP0003705_abnormal_hypodermis_morpholog3.26697633
7MP0002108_abnormal_muscle_morphology2.29378600
8MP0002060_abnormal_skin_morphology2.28781331
9MP0005257_abnormal_intraocular_pressure2.22129747
10MP0003011_delayed_dark_adaptation2.11829196
11MP0005508_abnormal_skeleton_morphology2.11660208
12MP0005623_abnormal_meninges_morphology2.10227368
13MP0004272_abnormal_basement_membrane2.08810229
14MP0005171_absent_coat_pigmentation1.88140957
15MP0000751_myopathy1.87665722
16MP0006054_spinal_hemorrhage1.84337118
17MP0009384_cardiac_valve_regurgitation1.67657887
18MP0010386_abnormal_urinary_bladder1.56791023
19MP0003566_abnormal_cell_adhesion1.55427790
20MP0001542_abnormal_bone_strength1.52100567
21MP0002933_joint_inflammation1.51837802
22MP0002254_reproductive_system_inflammat1.46873326
23MP0005390_skeleton_phenotype1.44801102
24MP0009250_abnormal_appendicular_skeleto1.42476258
25MP0005666_abnormal_adipose_tissue1.41951161
26MP0010368_abnormal_lymphatic_system1.37427225
27MP0002295_abnormal_pulmonary_circulatio1.36851436
28MP0003950_abnormal_plasma_membrane1.34787837
29MP0000013_abnormal_adipose_tissue1.30171546
30MP0000749_muscle_degeneration1.29690388
31MP0005023_abnormal_wound_healing1.29274215
32MP0003724_increased_susceptibility_to1.27537622
33MP0000750_abnormal_muscle_regeneration1.25849757
34MP0002998_abnormal_bone_remodeling1.23771191
35MP0005595_abnormal_vascular_smooth1.19985837
36MP0008004_abnormal_stomach_pH1.19883216
37MP0003091_abnormal_cell_migration1.19851580
38MP0003385_abnormal_body_wall1.17618803
39MP0004134_abnormal_chest_morphology1.17510829
40MP0010030_abnormal_orbit_morphology1.17452880
41MP0001243_abnormal_dermal_layer1.17416307
42MP0004233_abnormal_muscle_weight1.17371677
43MP0008775_abnormal_heart_ventricle1.16288997
44MP0001299_abnormal_eye_distance/1.15658180
45MP0004858_abnormal_nervous_system1.14756831
46MP0002896_abnormal_bone_mineralization1.14415741
47MP0001533_abnormal_skeleton_physiology1.12644512
48MP0000733_abnormal_muscle_development1.09607590
49MP0000767_abnormal_smooth_muscle1.05329103
50MP0000163_abnormal_cartilage_morphology1.03035056
51MP0003045_fibrosis1.01360131
52MP0005369_muscle_phenotype0.99363357
53MP0005670_abnormal_white_adipose0.98207607
54MP0002168_other_aberrant_phenotype0.97782083
55MP0002090_abnormal_vision0.96029869
56MP0002837_dystrophic_cardiac_calcinosis0.95162863
57MP0004084_abnormal_cardiac_muscle0.94953717
58MP0002115_abnormal_skeleton_extremities0.94621005
59MP0000759_abnormal_skeletal_muscle0.94139726
60MP0000343_altered_response_to0.93639731
61MP0001879_abnormal_lymphatic_vessel0.92337713
62MP0002133_abnormal_respiratory_system0.90688422
63MP0005388_respiratory_system_phenotype0.90688422
64MP0006138_congestive_heart_failure0.88890880
65MP0004510_myositis0.86611911
66MP0001177_atelectasis0.85918974
67MP0002089_abnormal_postnatal_growth/wei0.85319845
68MP0000249_abnormal_blood_vessel0.84694634
69MP0003941_abnormal_skin_development0.84383022
70MP0002971_abnormal_brown_adipose0.83175743
71MP0002113_abnormal_skeleton_development0.81778334
72MP0002932_abnormal_joint_morphology0.81506691
73MP0005164_abnormal_response_to0.80930436
74MP0003186_abnormal_redox_activity0.80400639
75MP0004145_abnormal_muscle_electrophysio0.80369032
76MP0005620_abnormal_muscle_contractility0.80285770
77MP0001346_abnormal_lacrimal_gland0.79143988
78MP0005165_increased_susceptibility_to0.78923040
79MP0009780_abnormal_chondrocyte_physiolo0.78608812
80MP0002234_abnormal_pharynx_morphology0.78123061
81MP0009764_decreased_sensitivity_to0.77876135
82MP0000003_abnormal_adipose_tissue0.77642701
83MP0002282_abnormal_trachea_morphology0.77529171
84MP0000467_abnormal_esophagus_morphology0.75149628
85MP0003828_pulmonary_edema0.75145551
86MP0003448_altered_tumor_morphology0.74603581
87MP0005409_darkened_coat_color0.74442117
88MP0009840_abnormal_foam_cell0.73763477
89MP0003795_abnormal_bone_structure0.73176588
90MP0004087_abnormal_muscle_fiber0.70582432
91MP0002106_abnormal_muscle_physiology0.69451519
92MP0001915_intracranial_hemorrhage0.68083445
93MP0005248_abnormal_Harderian_gland0.67881684
94MP0000428_abnormal_craniofacial_morphol0.65255586
95MP0004215_abnormal_myocardial_fiber0.65206452
96MP0000534_abnormal_ureter_morphology0.65090908
97MP0005197_abnormal_uvea_morphology0.65048149
98MP0001175_abnormal_lung_morphology0.64772312
99MP0004036_abnormal_muscle_relaxation0.63564678
100MP0001661_extended_life_span0.63288656
101MP0003300_gastrointestinal_ulcer0.61426217
102MP0008260_abnormal_autophagy0.60181914
103MP0002128_abnormal_blood_circulation0.59043168
104MP0002877_abnormal_melanocyte_morpholog0.57810283
105MP0010771_integument_phenotype0.57537042
106MP0005076_abnormal_cell_differentiation0.57108442
107MP0000747_muscle_weakness0.55966531
108MP0002972_abnormal_cardiac_muscle0.55759323
109MP0003453_abnormal_keratinocyte_physiol0.55515978
110MP0002925_abnormal_cardiovascular_devel0.55262208
111MP0004883_abnormal_blood_vessel0.55076511
112MP0002109_abnormal_limb_morphology0.54985155
113MP0000049_abnormal_middle_ear0.54292215
114MP0003191_abnormal_cellular_cholesterol0.54212296
115MP0003755_abnormal_palate_morphology0.54042036
116MP0010352_gastrointestinal_tract_polyps0.52680194
117MP0002796_impaired_skin_barrier0.52387757
118MP0005193_abnormal_anterior_eye0.51392709
119MP0004130_abnormal_muscle_cell0.51170740
120MP0005375_adipose_tissue_phenotype0.51139919
121MP0003075_altered_response_to0.49944240
122MP0005330_cardiomyopathy0.49310127
123MP0003115_abnormal_respiratory_system0.48932866
124MP0001348_abnormal_lacrimal_gland0.48149507
125MP0004782_abnormal_surfactant_physiolog0.47351913
126MP0000858_altered_metastatic_potential0.47275732
127MP0000762_abnormal_tongue_morphology0.46829597
128MP0001614_abnormal_blood_vessel0.46512099

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)8.44583735
2Premature rupture of membranes (HP:0001788)8.08096283
3Aortic dissection (HP:0002647)5.33981277
4Soft skin (HP:0000977)5.05116269
5Broad metatarsal (HP:0001783)4.87751999
6Follicular hyperkeratosis (HP:0007502)4.78442528
7Ankle contracture (HP:0006466)4.69236821
8Type 1 muscle fiber predominance (HP:0003803)4.40368574
9Aortic aneurysm (HP:0004942)4.32064089
10Increased connective tissue (HP:0009025)4.31965270
11Atrophic scars (HP:0001075)4.18443480
12Spinal rigidity (HP:0003306)4.01458646
13Dilatation of the ascending aorta (HP:0005111)3.94309096
14Shallow orbits (HP:0000586)3.92007066
15Fragile skin (HP:0001030)3.85782751
16Vertebral compression fractures (HP:0002953)3.80846941
17Cervical subluxation (HP:0003308)3.69347575
18Neonatal short-limb short stature (HP:0008921)3.68561294
19Bladder diverticulum (HP:0000015)3.65708561
20Abnormality of dentin (HP:0010299)3.54874596
21Peritonitis (HP:0002586)3.47511063
22Cerebral aneurysm (HP:0004944)3.46722345
23Blue sclerae (HP:0000592)3.38526782
24Vascular tortuosity (HP:0004948)3.35877188
25Slender build (HP:0001533)3.34491820
26Wrist flexion contracture (HP:0001239)3.29001595
27Wormian bones (HP:0002645)3.18723832
28Mitral valve prolapse (HP:0001634)3.17189328
29Mildly elevated creatine phosphokinase (HP:0008180)3.12818840
30Biconcave vertebral bodies (HP:0004586)3.08191423
31Arterial tortuosity (HP:0005116)3.04025844
32Genu recurvatum (HP:0002816)2.99261739
33Spondylolisthesis (HP:0003302)2.93790211
34Hyperextensible skin (HP:0000974)2.79207249
35Round ear (HP:0100830)2.78108692
36Congenital stationary night blindness (HP:0007642)2.78046946
37Increased variability in muscle fiber diameter (HP:0003557)2.73776414
38Abnormal delivery (HP:0001787)2.71710765
39Abnormality of complement system (HP:0005339)2.67550000
40Overgrowth (HP:0001548)2.66580399
41Aortic valve stenosis (HP:0001650)2.62457595
42Alopecia of scalp (HP:0002293)2.55118118
43Renal duplication (HP:0000075)2.50395258
44Abnormality of skeletal muscle fiber size (HP:0012084)2.49326906
45Joint laxity (HP:0001388)2.47748608
46Thick nail (HP:0001805)2.40842025
47Systemic lupus erythematosus (HP:0002725)2.40684332
48Spinal cord lesions (HP:0100561)2.37861660
49Syringomyelia (HP:0003396)2.37861660
50Complement deficiency (HP:0004431)2.37146055
51Striae distensae (HP:0001065)2.36991659
52Elbow flexion contracture (HP:0002987)2.36690221
53Bell-shaped thorax (HP:0001591)2.31186828
54Distal lower limb amyotrophy (HP:0008944)2.29823334
55Mesomelia (HP:0003027)2.27867394
56Bowel diverticulosis (HP:0005222)2.22913929
57Osteolytic defects of the hand bones (HP:0009699)2.19998013
58Osteolytic defects of the phalanges of the hand (HP:0009771)2.19998013
59Keratoconus (HP:0000563)2.19670721
60Increased corneal curvature (HP:0100692)2.19670721
61Flared iliac wings (HP:0002869)2.17593350
62Thin bony cortex (HP:0002753)2.13125561
63Breech presentation (HP:0001623)2.13043285
64Abnormality of incisor morphology (HP:0011063)2.12371332
65Coronal craniosynostosis (HP:0004440)2.11737521
66Delayed cranial suture closure (HP:0000270)2.11181515
67Narrow nasal bridge (HP:0000446)2.11080196
68Aneurysm (HP:0002617)2.10342108
69Abnormality of the acetabulum (HP:0003170)2.10333954
70Mitral regurgitation (HP:0001653)2.09834230
71Mitral stenosis (HP:0001718)2.09155205
72Flat cornea (HP:0007720)2.07876358
73Disproportionate tall stature (HP:0001519)2.07087492
74Gingival overgrowth (HP:0000212)2.06432070
75Broad ribs (HP:0000885)2.06047689
76Aortic regurgitation (HP:0001659)2.04636381
77Ectopia lentis (HP:0001083)2.04293927
78Osteoarthritis (HP:0002758)2.02309916
79Joint stiffness (HP:0001387)2.01330728
80Abnormality of the calf musculature (HP:0001430)2.00498086
81Persistence of primary teeth (HP:0006335)1.99971197
82Venous abnormality (HP:0002624)1.99126194
83Hematochezia (HP:0002573)1.98287139
84Generalized amyotrophy (HP:0003700)1.97998072
85Ovoid vertebral bodies (HP:0003300)1.95643967
86Muscle fiber splitting (HP:0003555)1.95296296
87Pulmonary artery stenosis (HP:0004415)1.95003817
88Congenital glaucoma (HP:0001087)1.93602543
89Distal lower limb muscle weakness (HP:0009053)1.93422658
90Acanthosis nigricans (HP:0000956)1.92072210
91Nonimmune hydrops fetalis (HP:0001790)1.91947268
92Wide anterior fontanel (HP:0000260)1.91899617
93Delayed closure of the anterior fontanelle (HP:0001476)1.89612237
94Polycythemia (HP:0001901)1.88962676
95Corneal dystrophy (HP:0001131)1.87778493
96Hypoplasia of the iris (HP:0007676)1.86897025
97Lower limb amyotrophy (HP:0007210)1.86577713
98Myocardial infarction (HP:0001658)1.86519677
99Venous insufficiency (HP:0005293)1.85931550
100Infantile muscular hypotonia (HP:0008947)1.84508372
101Spinal cord compression (HP:0002176)1.84256573
102Tetraparesis (HP:0002273)1.83965505
103Esophageal varix (HP:0002040)1.83878004
104Short nail (HP:0001799)1.82512785
105Hypoplasia of the odontoid process (HP:0003311)1.80632308
106Congenital sensorineural hearing impairment (HP:0008527)1.79342527
107Limb-girdle muscle weakness (HP:0003325)1.79215890
108Scapular winging (HP:0003691)1.78627886
109Thin skin (HP:0000963)1.76766816
110Coxa vara (HP:0002812)1.76519578
111Natal tooth (HP:0000695)1.76096485
112Cupped ribs (HP:0000887)1.75629368
113Hypoventilation (HP:0002791)1.74557274
114Axonal loss (HP:0003447)1.74104269
115Camptodactyly of toe (HP:0001836)1.73675506
116Absent frontal sinuses (HP:0002688)1.73136909
117Reduced subcutaneous adipose tissue (HP:0003758)1.72878655
118Inguinal hernia (HP:0000023)1.72713855
119Thoracolumbar scoliosis (HP:0002944)1.72565728
120Difficulty climbing stairs (HP:0003551)1.70157177
121Tarsal synostosis (HP:0008368)1.68902302
122Lipoatrophy (HP:0100578)1.67967140
123Tibial bowing (HP:0002982)1.66890460
124Bradycardia (HP:0001662)1.65788343
125Decreased subcutaneous fat (HP:0001002)1.64462156
126Protruding ear (HP:0000411)1.64346664
127Osteopenia (HP:0000938)1.63634918
128Decreased skull ossification (HP:0004331)1.63547260
129Knee flexion contracture (HP:0006380)1.62775124

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR24.57903746
2TTN3.27314605
3EPHA33.11231813
4PDGFRA2.57714431
5FER2.57185556
6LATS22.43523325
7SIK12.31048878
8LATS12.15135731
9RIPK11.96734435
10PRPF4B1.92744017
11NEK91.91131474
12TGFBR21.89617050
13FRK1.89004345
14STK241.88454227
15ERBB31.79370285
16TRPM71.78855754
17DMPK1.75596052
18STK31.72194549
19CAMKK21.70793654
20STK38L1.66293831
21EPHB21.62903182
22MAP3K131.62894409
23ZAK1.58421603
24ERN11.57692985
25PLK21.57304515
26CASK1.51746570
27INSRR1.48854427
28TRIB31.47191119
29BMX1.46366605
30JAK11.44003801
31TESK11.42103265
32ARAF1.40731542
33MUSK1.38739824
34GRK11.38646184
35TAOK21.37623460
36AKT31.34819631
37MYLK1.33287401
38NTRK11.32842044
39ROCK11.22955881
40MAP3K61.22376716
41IKBKB1.15364259
42IRAK11.14368778
43PDK21.14283066
44PIM21.13795944
45PIK3CA1.10256974
46SIK31.09225191
47OBSCN1.08842496
48MAPK71.05846011
49EIF2AK21.01115669
50PAK31.00771348
51PRKCE1.00291204
52CDK80.96007551
53MOS0.95332614
54CAMK1D0.95183836
55PAK20.95135087
56MAP3K140.92953505
57BMPR20.92792798
58RPS6KA40.90974899
59PTK2B0.90444632
60IRAK30.89902789
61GSK3A0.89814289
62PKN20.89370783
63PBK0.88226987
64GRK50.84735792
65KSR20.84540447
66MAPK40.84069830
67MAP4K20.83868792
68FGFR30.83334210
69PRKD20.83282204
70FLT30.82795715
71MAPKAPK30.81511410
72MST1R0.81424124
73EPHB10.80430387
74TYK20.78366263
75FGFR40.78156579
76FGFR10.77421820
77EEF2K0.77027073
78PIK3CG0.76791118
79MAPK120.76538131
80PRKCH0.75278716
81PDGFRB0.73133854
82MAP2K10.71063928
83CLK10.69384254
84STK380.66055432
85LIMK10.65216198
86NEK60.65010210
87NLK0.64472771
88PTK20.64266687
89PINK10.64150314
90NUAK10.62281393
91ROCK20.61367493
92INSR0.61202567
93CAMKK10.56612165
94ABL20.56286575
95PHKG20.54702773
96PHKG10.54702773
97KIT0.51772169
98MTOR0.50447309
99HIPK20.48383403
100MAP2K30.47298241
101MAP3K10.46283314
102TGFBR10.46279408
103ADRBK10.44651828
104JAK30.44162356
105CAMK2D0.43732880
106TNIK0.40949378
107SRC0.39861279
108ZAP700.39535418
109TBK10.38137096
110MAP3K70.37228974
111RAF10.36438228
112PAK40.36427755
113FES0.35956580
114MET0.35228358
115PAK60.34775877
116PRKG20.34363535
117CHUK0.34006981
118IRAK20.33722140
119CDC42BPA0.33459384
120HCK0.32938604
121ERBB40.32831368
122BRD40.32401532
123ABL10.31888348
124DAPK30.31575492
125PRKG10.31029762
126PRKAA20.29792038
127ILK0.29512948
128KDR0.28914606
129PRKD10.28761055
130MELK0.28757600
131TIE10.28115752
132RPS6KA20.27102462
133MAP3K30.27023033
134WNK10.26526488
135MAPK30.24254136
136SGK4940.24215110
137SGK2230.24215110

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.48830112
2Mineral absorption_Homo sapiens_hsa049782.88407348
3Malaria_Homo sapiens_hsa051442.79585870
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.48203726
5Dilated cardiomyopathy_Homo sapiens_hsa054142.28630002
6Complement and coagulation cascades_Homo sapiens_hsa046102.24732458
7Focal adhesion_Homo sapiens_hsa045102.15935389
8Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.09361360
9Protein digestion and absorption_Homo sapiens_hsa049742.07593295
10AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.91163843
11Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.88747464
12Rheumatoid arthritis_Homo sapiens_hsa053231.77316519
13Amoebiasis_Homo sapiens_hsa051461.76255233
14TNF signaling pathway_Homo sapiens_hsa046681.58910073
15Melanoma_Homo sapiens_hsa052181.52029455
16PPAR signaling pathway_Homo sapiens_hsa033201.51298463
17Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.50605091
18Phagosome_Homo sapiens_hsa041451.50122752
19Prion diseases_Homo sapiens_hsa050201.41553660
20Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.41169002
21Proteoglycans in cancer_Homo sapiens_hsa052051.39437413
22PI3K-Akt signaling pathway_Homo sapiens_hsa041511.37734229
23Toll-like receptor signaling pathway_Homo sapiens_hsa046201.32313847
24Nicotine addiction_Homo sapiens_hsa050331.19388120
25TGF-beta signaling pathway_Homo sapiens_hsa043501.15406666
26Adherens junction_Homo sapiens_hsa045201.14945553
27Circadian rhythm_Homo sapiens_hsa047101.12968245
28Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.11347555
29Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.11127574
30Synaptic vesicle cycle_Homo sapiens_hsa047211.08933828
31Toxoplasmosis_Homo sapiens_hsa051451.08226875
32Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.07980800
33Osteoclast differentiation_Homo sapiens_hsa043801.07067040
34Small cell lung cancer_Homo sapiens_hsa052221.06261878
35Other glycan degradation_Homo sapiens_hsa005111.05146364
36Leishmaniasis_Homo sapiens_hsa051401.03145152
37Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.02655347
38Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.02415314
39Dorso-ventral axis formation_Homo sapiens_hsa043201.01498299
40Salmonella infection_Homo sapiens_hsa051321.00860716
41Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.00705554
42Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.00599959
43HIF-1 signaling pathway_Homo sapiens_hsa040660.99244057
44NOD-like receptor signaling pathway_Homo sapiens_hsa046210.98545263
45Chronic myeloid leukemia_Homo sapiens_hsa052200.97812375
46Pancreatic cancer_Homo sapiens_hsa052120.97765395
47Morphine addiction_Homo sapiens_hsa050320.95612696
48Phenylalanine metabolism_Homo sapiens_hsa003600.94154003
49Fatty acid biosynthesis_Homo sapiens_hsa000610.93993740
50Viral myocarditis_Homo sapiens_hsa054160.93654220
51Platelet activation_Homo sapiens_hsa046110.93428214
52Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.91383684
53Central carbon metabolism in cancer_Homo sapiens_hsa052300.90411808
54Oxytocin signaling pathway_Homo sapiens_hsa049210.88758044
55Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.88569210
56Tuberculosis_Homo sapiens_hsa051520.85887052
57Graft-versus-host disease_Homo sapiens_hsa053320.85839419
58Hedgehog signaling pathway_Homo sapiens_hsa043400.84465106
59Renin secretion_Homo sapiens_hsa049240.82263678
60Vascular smooth muscle contraction_Homo sapiens_hsa042700.81198743
61Legionellosis_Homo sapiens_hsa051340.80564749
62Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.79885653
63Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.79668575
64Regulation of actin cytoskeleton_Homo sapiens_hsa048100.78969191
65NF-kappa B signaling pathway_Homo sapiens_hsa040640.78685785
66Pertussis_Homo sapiens_hsa051330.76139494
67AMPK signaling pathway_Homo sapiens_hsa041520.75578612
68cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75032034
69Type II diabetes mellitus_Homo sapiens_hsa049300.74203102
70GABAergic synapse_Homo sapiens_hsa047270.74171541
71Cholinergic synapse_Homo sapiens_hsa047250.73296311
72Vibrio cholerae infection_Homo sapiens_hsa051100.73004693
73MicroRNAs in cancer_Homo sapiens_hsa052060.73003393
74Adipocytokine signaling pathway_Homo sapiens_hsa049200.72460920
75Ras signaling pathway_Homo sapiens_hsa040140.72312750
76Glycosaminoglycan degradation_Homo sapiens_hsa005310.72156662
77Circadian entrainment_Homo sapiens_hsa047130.71520768
78Prostate cancer_Homo sapiens_hsa052150.70040290
79Calcium signaling pathway_Homo sapiens_hsa040200.69805034
80Notch signaling pathway_Homo sapiens_hsa043300.69679105
81Glioma_Homo sapiens_hsa052140.69580243
82Sulfur metabolism_Homo sapiens_hsa009200.68990504
83Hepatitis B_Homo sapiens_hsa051610.68754845
84Autoimmune thyroid disease_Homo sapiens_hsa053200.68709196
85Shigellosis_Homo sapiens_hsa051310.67749778
86Renal cell carcinoma_Homo sapiens_hsa052110.67471447
87Hippo signaling pathway_Homo sapiens_hsa043900.66119080
88Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.65890092
89Lysosome_Homo sapiens_hsa041420.65592628
90Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.65372317
91MAPK signaling pathway_Homo sapiens_hsa040100.65113338
92Acute myeloid leukemia_Homo sapiens_hsa052210.65031408
93Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.64513618
94Gap junction_Homo sapiens_hsa045400.64302252
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64010053
96Apoptosis_Homo sapiens_hsa042100.63240942
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63083051
98Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.62859060
99Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.61466283
100Jak-STAT signaling pathway_Homo sapiens_hsa046300.61347809
101Rap1 signaling pathway_Homo sapiens_hsa040150.59449209
102Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.59422714
103FoxO signaling pathway_Homo sapiens_hsa040680.59167349
104Ovarian steroidogenesis_Homo sapiens_hsa049130.58641329
105Leukocyte transendothelial migration_Homo sapiens_hsa046700.58570167
106Salivary secretion_Homo sapiens_hsa049700.58247001
107Longevity regulating pathway - mammal_Homo sapiens_hsa042110.57831850
108Pathways in cancer_Homo sapiens_hsa052000.57599138
109Insulin resistance_Homo sapiens_hsa049310.55733283
110SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55155275
111Basal cell carcinoma_Homo sapiens_hsa052170.53550697
112Bladder cancer_Homo sapiens_hsa052190.53363673
113Axon guidance_Homo sapiens_hsa043600.52821515
114African trypanosomiasis_Homo sapiens_hsa051430.52517556
115Arachidonic acid metabolism_Homo sapiens_hsa005900.51747565
116GnRH signaling pathway_Homo sapiens_hsa049120.51571156
117VEGF signaling pathway_Homo sapiens_hsa043700.51405484
118cAMP signaling pathway_Homo sapiens_hsa040240.51206657
119Staphylococcus aureus infection_Homo sapiens_hsa051500.50797122
120Measles_Homo sapiens_hsa051620.50732532
121Chemokine signaling pathway_Homo sapiens_hsa040620.50424103
122p53 signaling pathway_Homo sapiens_hsa041150.50339312
123Phospholipase D signaling pathway_Homo sapiens_hsa040720.50134085
124Allograft rejection_Homo sapiens_hsa053300.50095609
125Tyrosine metabolism_Homo sapiens_hsa003500.46951441
126Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.46640613
127Tight junction_Homo sapiens_hsa045300.45291766
128Sphingolipid signaling pathway_Homo sapiens_hsa040710.44851191
129Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.41461053
130Insulin signaling pathway_Homo sapiens_hsa049100.40868896
131Estrogen signaling pathway_Homo sapiens_hsa049150.40695240
132Hematopoietic cell lineage_Homo sapiens_hsa046400.39410183
133Melanogenesis_Homo sapiens_hsa049160.39407536
134Galactose metabolism_Homo sapiens_hsa000520.39147158
135Endocytosis_Homo sapiens_hsa041440.38875906
136Sphingolipid metabolism_Homo sapiens_hsa006000.38261649

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »