MEIOC

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptonemal complex organization (GO:0070193)9.80725475
2synaptonemal complex assembly (GO:0007130)9.63582323
3fusion of sperm to egg plasma membrane (GO:0007342)8.63097077
4DNA methylation involved in gamete generation (GO:0043046)8.61152449
5regulation of meiosis I (GO:0060631)7.69229102
6male meiosis I (GO:0007141)7.42968041
7axonemal dynein complex assembly (GO:0070286)7.26923283
8sperm motility (GO:0030317)7.09598155
9chromosome organization involved in meiosis (GO:0070192)7.02207693
10sperm-egg recognition (GO:0035036)7.00914578
11binding of sperm to zona pellucida (GO:0007339)6.86363640
12acrosome assembly (GO:0001675)6.82797239
13spermatid development (GO:0007286)6.76066598
14meiotic nuclear division (GO:0007126)6.66365543
15multicellular organism reproduction (GO:0032504)6.47757182
16plasma membrane fusion (GO:0045026)6.45970655
17cell-cell recognition (GO:0009988)6.22622318
18meiosis I (GO:0007127)6.21111391
19nuclear pore complex assembly (GO:0051292)6.19496888
20epithelial cilium movement (GO:0003351)6.15774895
21motile cilium assembly (GO:0044458)6.04570681
22epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.01470877
23nuclear pore organization (GO:0006999)5.60623128
24gene silencing by RNA (GO:0031047)5.52897966
25cilium movement (GO:0003341)5.49773612
26acrosome reaction (GO:0007340)5.49208860
27meiotic cell cycle (GO:0051321)5.22292355
28reproduction (GO:0000003)5.16439399
29response to pheromone (GO:0019236)4.96135055
30protein polyglutamylation (GO:0018095)4.85258404
31meiotic cell cycle process (GO:1903046)4.80722076
32germ cell development (GO:0007281)4.75802783
33pore complex assembly (GO:0046931)4.69571835
34centriole replication (GO:0007099)4.61969751
35fertilization (GO:0009566)4.58361186
36cell wall macromolecule catabolic process (GO:0016998)4.50722668
37cell wall macromolecule metabolic process (GO:0044036)4.50722668
38spermatogenesis (GO:0007283)4.47496234
39male gamete generation (GO:0048232)4.46611016
40regulation of cilium movement (GO:0003352)4.45481778
41cellular process involved in reproduction in multicellular organism (GO:0022412)4.41677764
42regulation of centriole replication (GO:0046599)4.40447252
43regulation of histone H3-K9 methylation (GO:0051570)4.38710011
44single fertilization (GO:0007338)4.38201892
45establishment of protein localization to Golgi (GO:0072600)4.36684667
46DNA methylation (GO:0006306)4.30456541
47DNA alkylation (GO:0006305)4.30456541
48monoubiquitinated protein deubiquitination (GO:0035520)4.28949580
49negative regulation of inclusion body assembly (GO:0090084)4.27023452
50negative regulation of DNA repair (GO:0045738)4.24270007
51genitalia morphogenesis (GO:0035112)4.23839393
52regulation of protein polyubiquitination (GO:1902914)4.22900324
53rRNA methylation (GO:0031167)4.20155062
54microtubule depolymerization (GO:0007019)4.18630438
55gamete generation (GO:0007276)4.15797581
56protein targeting to Golgi (GO:0000042)4.13205819
57sister chromatid cohesion (GO:0007062)4.06315433
58synapsis (GO:0007129)4.01805564
59gene silencing (GO:0016458)3.94890510
60seminiferous tubule development (GO:0072520)3.93664320
61single strand break repair (GO:0000012)3.93471860
62rRNA modification (GO:0000154)3.76068637
63retrograde transport, vesicle recycling within Golgi (GO:0000301)3.75537453
64mitotic sister chromatid cohesion (GO:0007064)3.73912763
65chaperone-mediated protein complex assembly (GO:0051131)3.71233706
66DNA replication-dependent nucleosome organization (GO:0034723)3.68762771
67DNA replication-dependent nucleosome assembly (GO:0006335)3.68762771
68microtubule polymerization or depolymerization (GO:0031109)3.65773646
69behavioral response to nicotine (GO:0035095)3.61948037
70protein localization to Golgi apparatus (GO:0034067)3.57979213
71ventricular system development (GO:0021591)3.54319860
72histone exchange (GO:0043486)3.53279494
73negative regulation of meiosis (GO:0045835)3.51742376
74sperm capacitation (GO:0048240)3.47129926
75negative regulation of organelle assembly (GO:1902116)3.43065402
76reciprocal DNA recombination (GO:0035825)3.42913440
77reciprocal meiotic recombination (GO:0007131)3.42913440
78centriole assembly (GO:0098534)3.42383273
79regulation of inclusion body assembly (GO:0090083)3.39441109
80heterochromatin organization (GO:0070828)3.38691992
81cellular ketone body metabolic process (GO:0046950)3.37516006
82DNA methylation or demethylation (GO:0044728)3.37338243
83translesion synthesis (GO:0019985)3.32704670
84axoneme assembly (GO:0035082)3.32237734
85oogenesis (GO:0048477)3.28323371
86indolalkylamine catabolic process (GO:0046218)3.27434212
87tryptophan catabolic process (GO:0006569)3.27434212
88indole-containing compound catabolic process (GO:0042436)3.27434212
89protein localization to cilium (GO:0061512)3.26979371
90meiotic chromosome segregation (GO:0045132)3.25235098
91intraciliary transport (GO:0042073)3.24973449
92multicellular organismal reproductive process (GO:0048609)3.24918210
93sex differentiation (GO:0007548)3.23986955
94DNA packaging (GO:0006323)3.23201844
95protein K11-linked deubiquitination (GO:0035871)3.21827759
96ketone body metabolic process (GO:1902224)3.19777726
97calcium ion-dependent exocytosis (GO:0017156)3.18489554
98detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.18314466
99nucleus organization (GO:0006997)3.18194600
100regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.16081308
101detection of light stimulus involved in sensory perception (GO:0050962)3.14363100
102detection of light stimulus involved in visual perception (GO:0050908)3.14363100
103regulation of RNA export from nucleus (GO:0046831)3.13997782
104regulation of DNA endoreduplication (GO:0032875)3.12981360
105L-fucose catabolic process (GO:0042355)3.08528312
106fucose catabolic process (GO:0019317)3.08528312
107L-fucose metabolic process (GO:0042354)3.08528312
108regulation of centrosome cycle (GO:0046605)3.07477345
109chromosome condensation (GO:0030261)3.05693223
110indolalkylamine metabolic process (GO:0006586)3.05508284
111double-strand break repair via homologous recombination (GO:0000724)3.04207571
112negative regulation of DNA-dependent DNA replication (GO:2000104)3.03508736
113recombinational repair (GO:0000725)3.02129273
114phosphatidylethanolamine biosynthetic process (GO:0006646)3.01908749
115spermatid nucleus differentiation (GO:0007289)3.01221877
116mitotic chromosome condensation (GO:0007076)3.00389866
117resolution of meiotic recombination intermediates (GO:0000712)2.99508408
118mitotic sister chromatid segregation (GO:0000070)2.99411698
119protein K6-linked ubiquitination (GO:0085020)2.98799552
120protein localization to chromosome, centromeric region (GO:0071459)2.98224529
121phosphatidylethanolamine metabolic process (GO:0046337)2.96086287
122mitotic nuclear envelope disassembly (GO:0007077)2.95509864
123regulation of chromatin binding (GO:0035561)2.94091588
124positive regulation of mitotic sister chromatid separation (GO:1901970)2.93800944
125positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.93800944
126positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.93800944
127regulation of nuclear cell cycle DNA replication (GO:0033262)2.93649005
128regulation of microtubule-based movement (GO:0060632)2.93403451
129nonmotile primary cilium assembly (GO:0035058)2.93380752
130cilium morphogenesis (GO:0060271)2.92791060
131photoreceptor cell maintenance (GO:0045494)2.90892541
132kynurenine metabolic process (GO:0070189)2.89287334
133cilium organization (GO:0044782)2.87812718
134left/right pattern formation (GO:0060972)2.87722748
135replication fork processing (GO:0031297)2.86532994
136chromosome organization (GO:0051276)2.85851374
137regulation of chromosome segregation (GO:0051983)2.84623228
138oocyte development (GO:0048599)2.83928163
139regulation of spindle checkpoint (GO:0090231)2.83378338
140cilium assembly (GO:0042384)2.81466378
141water-soluble vitamin biosynthetic process (GO:0042364)2.78834481
142spinal cord motor neuron differentiation (GO:0021522)2.76427946
143RNA destabilization (GO:0050779)2.76129272
144positive regulation of meiosis (GO:0045836)2.73187146
145tryptophan metabolic process (GO:0006568)2.71853442
146DNA double-strand break processing (GO:0000729)2.65495679
147mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.62664398
148mitochondrial respiratory chain complex I assembly (GO:0032981)2.62664398
149NADH dehydrogenase complex assembly (GO:0010257)2.62664398
150sulfation (GO:0051923)2.62334568
151regulation of telomere maintenance (GO:0032204)2.61498467
152microtubule nucleation (GO:0007020)2.59588563
153microtubule severing (GO:0051013)2.58904856
154piRNA metabolic process (GO:0034587)12.5903033
155cilium or flagellum-dependent cell motility (GO:0001539)11.3005987
156male meiosis (GO:0007140)10.1506560

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.49028398
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.96475189
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.55727549
4EZH2_22144423_ChIP-Seq_EOC_Human3.32908573
5SALL1_21062744_ChIP-ChIP_HESCs_Human2.95434961
6VDR_22108803_ChIP-Seq_LS180_Human2.78903729
7E2F4_17652178_ChIP-ChIP_JURKAT_Human2.77282212
8GBX2_23144817_ChIP-Seq_PC3_Human2.73536040
9CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.69354126
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.67171926
11CTBP2_25329375_ChIP-Seq_LNCAP_Human2.45098455
12KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.45015933
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.43880018
14TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.42941918
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.37975067
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.34712085
17TAF15_26573619_Chip-Seq_HEK293_Human2.24817833
18CTBP1_25329375_ChIP-Seq_LNCAP_Human2.24496494
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.21236893
20P300_19829295_ChIP-Seq_ESCs_Human2.18752709
21RBPJ_22232070_ChIP-Seq_NCS_Mouse2.15686448
22ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.09553455
23IGF1R_20145208_ChIP-Seq_DFB_Human2.07310126
24EWS_26573619_Chip-Seq_HEK293_Human2.06055365
25ER_23166858_ChIP-Seq_MCF-7_Human2.05930230
26GATA1_26923725_Chip-Seq_HPCs_Mouse2.00161336
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse11.4896739
28CBP_20019798_ChIP-Seq_JUKART_Human1.99724259
29IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.99724259
30UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.86015667
31EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.85345702
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.83205352
33KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.81447359
34KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.81447359
35KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.81447359
36MYCN_18555785_ChIP-Seq_MESCs_Mouse1.81078988
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.76915288
38AR_21909140_ChIP-Seq_LNCAP_Human1.76324789
39AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.71809611
40HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.66702858
41CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.66068171
42STAT3_23295773_ChIP-Seq_U87_Human1.65823974
43SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.63228214
44PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.62543154
45SMAD4_21799915_ChIP-Seq_A2780_Human1.59595230
46AR_25329375_ChIP-Seq_VCAP_Human1.56106706
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.48694124
48ELK4_26923725_Chip-Seq_MESODERM_Mouse1.48065891
49TP53_22573176_ChIP-Seq_HFKS_Human1.45595897
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.45407133
51MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.45372682
52MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44188102
53SMAD4_21741376_ChIP-Seq_EPCs_Human1.42601728
54KLF5_20875108_ChIP-Seq_MESCs_Mouse1.41964968
55NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.41726543
56E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.40878911
57GABP_17652178_ChIP-ChIP_JURKAT_Human1.39732506
58TOP2B_26459242_ChIP-Seq_MCF-7_Human1.39490501
59SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.39368878
60MYC_18940864_ChIP-ChIP_HL60_Human1.38568111
61PCGF2_27294783_Chip-Seq_ESCs_Mouse1.35900291
62NANOG_19829295_ChIP-Seq_ESCs_Human1.35623806
63SOX2_19829295_ChIP-Seq_ESCs_Human1.35623806
64NR3C1_21868756_ChIP-Seq_MCF10A_Human1.33592057
65POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.32926422
66E2F1_21310950_ChIP-Seq_MCF-7_Human1.32097875
67PIAS1_25552417_ChIP-Seq_VCAP_Human1.32060310
68RUNX2_22187159_ChIP-Seq_PCA_Human1.31841384
69KAP1_22055183_ChIP-Seq_ESCs_Mouse1.30668397
70TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.29756004
71BMI1_23680149_ChIP-Seq_NPCS_Mouse1.29660413
72RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.28789410
73ZNF274_21170338_ChIP-Seq_K562_Hela1.28363466
74NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.27722230
75PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.27271589
76STAT6_21828071_ChIP-Seq_BEAS2B_Human1.26981229
77TCF4_22108803_ChIP-Seq_LS180_Human1.26191109
78KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.26143713
79IRF1_19129219_ChIP-ChIP_H3396_Human1.24770605
80FOXA1_25329375_ChIP-Seq_VCAP_Human1.24173294
81FOXA1_27270436_Chip-Seq_PROSTATE_Human1.24173294
82AUTS2_25519132_ChIP-Seq_293T-REX_Human1.23327020
83NOTCH1_21737748_ChIP-Seq_TLL_Human1.21948064
84EST1_17652178_ChIP-ChIP_JURKAT_Human1.21507869
85FOXA1_21572438_ChIP-Seq_LNCaP_Human1.20698746
86MYC_18555785_ChIP-Seq_MESCs_Mouse1.20481105
87GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.18940820
88NCOR_22424771_ChIP-Seq_293T_Human1.18062970
89CBX2_27304074_Chip-Seq_ESCs_Mouse1.17942110
90WDR5_24793694_ChIP-Seq_LNCAP_Human1.15541043
91MYC_19079543_ChIP-ChIP_MESCs_Mouse1.15050824
92EZH2_27294783_Chip-Seq_NPCs_Mouse1.14354547
93HOXB7_26014856_ChIP-Seq_BT474_Human1.13695437
94RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.13238022
95PRDM14_20953172_ChIP-Seq_ESCs_Human1.11252723
96ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.11161624
97STAT3_1855785_ChIP-Seq_MESCs_Mouse1.11080964
98NANOG_18555785_Chip-Seq_ESCs_Mouse1.10917393
99FLI1_21867929_ChIP-Seq_TH2_Mouse1.10878099
100GATA3_21878914_ChIP-Seq_MCF-7_Human1.10845350
101CDX2_22108803_ChIP-Seq_LS180_Human1.10721260
102SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09967542
103ETV1_20927104_ChIP-Seq_GIST48_Human1.09103707
104SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.07420467
105FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.06944469
106HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.04648293
107PHF8_20622853_ChIP-Seq_HELA_Human1.03609518
108ELK1_19687146_ChIP-ChIP_HELA_Human1.03522157
109ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03511843
110KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03229520
111TBL1_22424771_ChIP-Seq_293T_Human1.03225201
112MYC_19829295_ChIP-Seq_ESCs_Human1.03196991
113PCGF2_27294783_Chip-Seq_NPCs_Mouse1.02333654
114NELFA_20434984_ChIP-Seq_ESCs_Mouse1.01725718
115RBPJ_21746931_ChIP-Seq_IB4_Human1.00246354
116AR_21572438_ChIP-Seq_LNCaP_Human0.98917763
117OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98915635
118CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98264278
119PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.98164404
120MYC_19030024_ChIP-ChIP_MESCs_Mouse0.97987602
121REST_21632747_ChIP-Seq_MESCs_Mouse0.97965529
122AR_20517297_ChIP-Seq_VCAP_Human0.97718553
123NFE2_27457419_Chip-Seq_LIVER_Mouse0.96597115
124HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.95829945
125SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.95318435
126KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.95033440
127RNF2_27304074_Chip-Seq_NSC_Mouse0.94998821
128TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.89878692
129GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.89870007
130STAT1_17558387_ChIP-Seq_HELA_Human0.89451373
131KDM5A_27292631_Chip-Seq_BREAST_Human0.89027522
132CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88499841
133RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.88160525
134GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.88096916
135FUS_26573619_Chip-Seq_HEK293_Human0.86948632
136CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.86877618
137PKCTHETA_26484144_Chip-Seq_BREAST_Human0.85225992
138RUNX1_26923725_Chip-Seq_HPCs_Mouse0.84363969
139EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.82613814
140PADI4_21655091_ChIP-ChIP_MCF-7_Human0.81588621
141SUZ12_27294783_Chip-Seq_NPCs_Mouse0.80867224
142TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.78700956
143XRN2_22483619_ChIP-Seq_HELA_Human0.77738615
144STAT3_18555785_ChIP-Seq_MESCs_Mouse0.75459941
145ZFX_18555785_ChIP-Seq_MESCs_Mouse0.74966230
146TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse0.74187483
147SOX2_22085726_ChIP-Seq_NPCs_Mouse0.73933862
148TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.73490521
149POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.73490521
150MYC_18358816_ChIP-ChIP_MESCs_Mouse0.72981784
151TCF4_23295773_ChIP-Seq_U87_Human0.72944246
152SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.72067911
153MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.71949231
154E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.71024298
155DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.70515297
156CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.70146562
157POU5F1_16518401_ChIP-PET_MESCs_Mouse0.69630929
158GATA3_21867929_ChIP-Seq_CD8_Mouse0.69481790
159RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.68776699
160NANOG_21062744_ChIP-ChIP_HESCs_Human0.68714945
161CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.68579020
162BCAT_22108803_ChIP-Seq_LS180_Human0.67737109
163TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.67654493
164LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.67017519
165SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.64508763
166OCT4_18555785_Chip-Seq_ESCs_Mouse0.63564071
167DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.63287070
168CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.63044037
169YY1_22570637_ChIP-Seq_MALME-3M_Human0.62974943
170SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.62471208
171TAL1_26923725_Chip-Seq_HPCs_Mouse0.62198074
172NFYB_21822215_ChIP-Seq_K562_Human0.62048242
173NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.61095214

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization8.75083414
2MP0008877_abnormal_DNA_methylation7.73905935
3MP0001929_abnormal_gametogenesis4.72400254
4MP0008057_abnormal_DNA_replication4.53675576
5MP0003698_abnormal_male_reproductive4.52792710
6MP0002210_abnormal_sex_determination4.17201924
7MP0001145_abnormal_male_reproductive3.48481985
8MP0002653_abnormal_ependyma_morphology3.31895493
9MP0010094_abnormal_chromosome_stability3.27609063
10MP0000653_abnormal_sex_gland3.06523302
11MP0002161_abnormal_fertility/fecundity2.59170590
12MP0008058_abnormal_DNA_repair2.56583380
13MP0008995_early_reproductive_senescence2.51427265
14MP0003111_abnormal_nucleus_morphology2.51000792
15MP0003786_premature_aging2.42724100
16MP0008007_abnormal_cellular_replicative2.33550233
17MP0005551_abnormal_eye_electrophysiolog2.26734191
18MP0003077_abnormal_cell_cycle2.21424588
19MP0002160_abnormal_reproductive_system2.13710826
20MP0001968_abnormal_touch/_nociception2.06622625
21MP0010307_abnormal_tumor_latency2.04827854
22MP0003693_abnormal_embryo_hatching2.03386209
23MP0003136_yellow_coat_color2.00257806
24MP0003195_calcinosis1.97424779
25MP0001485_abnormal_pinna_reflex1.95944628
26MP0006292_abnormal_olfactory_placode1.94241052
27MP0004957_abnormal_blastocyst_morpholog1.91895089
28MP0005623_abnormal_meninges_morphology1.90941785
29MP0005253_abnormal_eye_physiology1.80722186
30MP0000372_irregular_coat_pigmentation1.72066841
31MP0001730_embryonic_growth_arrest1.63143829
32MP0002736_abnormal_nociception_after1.61368153
33MP0003123_paternal_imprinting1.58551885
34MP0005379_endocrine/exocrine_gland_phen1.56972688
35MP0001486_abnormal_startle_reflex1.56449190
36MP0005646_abnormal_pituitary_gland1.55689505
37MP0003878_abnormal_ear_physiology1.55191095
38MP0005377_hearing/vestibular/ear_phenot1.55191095
39MP0009046_muscle_twitch1.52433653
40MP0000631_abnormal_neuroendocrine_gland1.51453312
41MP0001984_abnormal_olfaction1.49857872
42MP0008872_abnormal_physiological_respon1.48785711
43MP0005174_abnormal_tail_pigmentation1.46059736
44MP0005084_abnormal_gallbladder_morpholo1.41196255
45MP0002837_dystrophic_cardiac_calcinosis1.39220611
46MP0009745_abnormal_behavioral_response1.39046994
47MP0005645_abnormal_hypothalamus_physiol1.37503040
48MP0002938_white_spotting1.37019015
49MP0005647_abnormal_sex_gland1.34984203
50MP0005076_abnormal_cell_differentiation1.34167422
51MP0002272_abnormal_nervous_system1.32561997
52MP0003880_abnormal_central_pattern1.31407192
53MP0002084_abnormal_developmental_patter1.29064549
54MP0006276_abnormal_autonomic_nervous1.26572907
55MP0004142_abnormal_muscle_tone1.26032440
56MP0002928_abnormal_bile_duct1.23477967
57MP0002138_abnormal_hepatobiliary_system1.20918884
58MP0000350_abnormal_cell_proliferation1.20880213
59MP0004742_abnormal_vestibular_system1.20082614
60MP0005389_reproductive_system_phenotype1.19872391
61MP0002234_abnormal_pharynx_morphology1.18714215
62MP0003646_muscle_fatigue1.17583591
63MP0004197_abnormal_fetal_growth/weight/1.16059034
64MP0001672_abnormal_embryogenesis/_devel1.14653983
65MP0005380_embryogenesis_phenotype1.14653983
66MP0002735_abnormal_chemical_nociception1.13924940
67MP0008932_abnormal_embryonic_tissue1.12596410
68MP0002638_abnormal_pupillary_reflex1.12369660
69MP0002876_abnormal_thyroid_physiology1.09318512
70MP0001697_abnormal_embryo_size1.09178575
71MP0001119_abnormal_female_reproductive1.09028264
72MP0001529_abnormal_vocalization1.08665340
73MP0001986_abnormal_taste_sensitivity1.07972523
74MP0002085_abnormal_embryonic_tissue1.07275880
75MP0008789_abnormal_olfactory_epithelium1.05297892
76MP0003011_delayed_dark_adaptation1.04464427
77MP0001501_abnormal_sleep_pattern1.04306525
78MP0002163_abnormal_gland_morphology1.03110372
79MP0002557_abnormal_social/conspecific_i1.02294145
80MP0002282_abnormal_trachea_morphology1.02284721
81MP0003121_genomic_imprinting1.01011455
82MP0002095_abnormal_skin_pigmentation1.00570658
83MP0003890_abnormal_embryonic-extraembry1.00498779
84MP0004808_abnormal_hematopoietic_stem0.98762550
85MP0000383_abnormal_hair_follicle0.98715503
86MP0002067_abnormal_sensory_capabilities0.98299523
87MP0002572_abnormal_emotion/affect_behav0.97945743
88MP0000015_abnormal_ear_pigmentation0.96339767
89MP0010352_gastrointestinal_tract_polyps0.95636186
90MP0001963_abnormal_hearing_physiology0.95586193
91MP0003984_embryonic_growth_retardation0.94976462
92MP0001293_anophthalmia0.94937725
93MP0003699_abnormal_female_reproductive0.91831460
94MP0002088_abnormal_embryonic_growth/wei0.91658192
95MP0005310_abnormal_salivary_gland0.89881088
96MP0004885_abnormal_endolymph0.89822100
97MP0004215_abnormal_myocardial_fiber0.89457749
98MP0004043_abnormal_pH_regulation0.87469947
99MP0000026_abnormal_inner_ear0.87158966
100MP0009697_abnormal_copulation0.86944663
101MP0000569_abnormal_digit_pigmentation0.86731507
102MP0002086_abnormal_extraembryonic_tissu0.86389063
103MP0002080_prenatal_lethality0.86268690
104MP0005195_abnormal_posterior_eye0.85785664
105MP0004134_abnormal_chest_morphology0.85119287
106MP0001970_abnormal_pain_threshold0.84874062
107MP0005386_behavior/neurological_phenoty0.84297749
108MP0004924_abnormal_behavior0.84297749
109MP0004233_abnormal_muscle_weight0.84290659
110MP0000313_abnormal_cell_death0.83381802
111MP0003787_abnormal_imprinting0.82479659
112MP0008875_abnormal_xenobiotic_pharmacok0.82015314
113MP0002733_abnormal_thermal_nociception0.81693772
114MP0002229_neurodegeneration0.80030223
115MP0002064_seizures0.79986197
116MP0005367_renal/urinary_system_phenotyp0.79656770
117MP0000516_abnormal_urinary_system0.79656770
118MP0001324_abnormal_eye_pigmentation0.78575630
119MP0004085_abnormal_heartbeat0.76775313
120MP0009672_abnormal_birth_weight0.74770521
121MP0003115_abnormal_respiratory_system0.74626936
122MP0003936_abnormal_reproductive_system0.74564019
123MP0000427_abnormal_hair_cycle0.74472540
124MP0004133_heterotaxia0.74302065
125MP0001727_abnormal_embryo_implantation0.73765851
126MP0000537_abnormal_urethra_morphology0.73744823
127MP0003861_abnormal_nervous_system0.70381800
128MP0003119_abnormal_digestive_system0.67248686
129MP0009703_decreased_birth_body0.67151041
130MP0000358_abnormal_cell_content/0.66897040
131MP0003718_maternal_effect0.66692990
132MP0001661_extended_life_span0.65770907
133MP0005397_hematopoietic_system_phenotyp0.63428146
134MP0001545_abnormal_hematopoietic_system0.63428146
135MP0009278_abnormal_bone_marrow0.62788518
136MP0005670_abnormal_white_adipose0.62456280
137MP0003937_abnormal_limbs/digits/tail_de0.59152819
138MP0002102_abnormal_ear_morphology0.57920101
139MP0003315_abnormal_perineum_morphology0.57213207
140MP0003950_abnormal_plasma_membrane0.55396287
141MP0000432_abnormal_head_morphology0.54650968
142MP0002092_abnormal_eye_morphology0.54259641
143MP0001915_intracranial_hemorrhage0.52249272
144MP0002019_abnormal_tumor_incidence0.49947372
145MP0002697_abnormal_eye_size0.46588239
146MP0005666_abnormal_adipose_tissue0.46038716
147MP0005391_vision/eye_phenotype0.43124158
148MP0006072_abnormal_retinal_apoptosis0.41437987
149MP0004264_abnormal_extraembryonic_tissu0.40904646
150MP0005384_cellular_phenotype0.40458904
151MP0005266_abnormal_metabolism0.39854028
152MP0003283_abnormal_digestive_organ0.39514759
153MP0005621_abnormal_cell_physiology0.38554736
154MP0001849_ear_inflammation0.38451874
155MP0000647_abnormal_sebaceous_gland0.37689192
156MP0002233_abnormal_nose_morphology0.34932479
157MP0005395_other_phenotype0.34721014
158MP0002114_abnormal_axial_skeleton0.33879675
159MP0002152_abnormal_brain_morphology0.32864326
160MP0001919_abnormal_reproductive_system0.30528844
161MP0002925_abnormal_cardiovascular_devel0.30498959
162MP0003935_abnormal_craniofacial_develop0.29889478
163MP0001784_abnormal_fluid_regulation0.29660311
164MP0006138_congestive_heart_failure0.29083574

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)9.33302378
2Absent/shortened dynein arms (HP:0200106)9.33302378
3Abnormal respiratory motile cilium physiology (HP:0012261)7.13288346
4Abnormal respiratory motile cilium morphology (HP:0005938)6.47074290
5Abnormal respiratory epithelium morphology (HP:0012253)6.47074290
6Rhinitis (HP:0012384)6.37481023
7Chronic bronchitis (HP:0004469)5.70497811
8Abnormality of the lower motor neuron (HP:0002366)5.57925519
9Abnormal ciliary motility (HP:0012262)5.57723416
10Infertility (HP:0000789)5.02418381
11Gonadotropin excess (HP:0000837)4.83842475
12Nasal polyposis (HP:0100582)4.67321623
1311 pairs of ribs (HP:0000878)4.16892885
14Pancreatic cysts (HP:0001737)4.13600394
15Nephronophthisis (HP:0000090)4.08886066
16Chronic hepatic failure (HP:0100626)4.01607957
17Amyotrophic lateral sclerosis (HP:0007354)3.89947321
18Pancreatic fibrosis (HP:0100732)3.83104609
19Fibular hypoplasia (HP:0003038)3.74437571
20Attenuation of retinal blood vessels (HP:0007843)3.71712553
21Abnormality of the nasal mucosa (HP:0000433)3.71703682
22Abnormal spermatogenesis (HP:0008669)3.67997964
23Azoospermia (HP:0000027)3.64913106
24Bronchiectasis (HP:0002110)3.63861832
25True hermaphroditism (HP:0010459)3.60814020
26Degeneration of anterior horn cells (HP:0002398)3.36638307
27Abnormality of the anterior horn cell (HP:0006802)3.36638307
28Upper motor neuron abnormality (HP:0002127)3.32797288
29Male infertility (HP:0003251)3.32562871
30Bronchitis (HP:0012387)3.28650917
31Selective tooth agenesis (HP:0001592)3.20642108
32Tubulointerstitial nephritis (HP:0001970)3.17848738
33Impulsivity (HP:0100710)3.13634138
34Congenital stationary night blindness (HP:0007642)3.11338300
35Abnormality of the renal medulla (HP:0100957)3.09902244
36Supernumerary spleens (HP:0009799)3.05622013
37Severe visual impairment (HP:0001141)3.04708840
38Type II lissencephaly (HP:0007260)2.98781211
39Bony spicule pigmentary retinopathy (HP:0007737)2.95581297
40Missing ribs (HP:0000921)2.90538822
41Pendular nystagmus (HP:0012043)2.83718140
42Abnormal rod and cone electroretinograms (HP:0008323)2.82784817
43Progressive cerebellar ataxia (HP:0002073)2.73821835
44Hyperventilation (HP:0002883)2.62727571
45Impaired proprioception (HP:0010831)2.61182744
46Cystic liver disease (HP:0006706)2.59389972
47Abnormal drinking behavior (HP:0030082)2.48688091
48Polydipsia (HP:0001959)2.48688091
49Cerebellar dysplasia (HP:0007033)2.47711782
50Gaze-evoked nystagmus (HP:0000640)2.47627916
51Aplasia/Hypoplasia of the fibula (HP:0006492)2.46925755
52Abolished electroretinogram (ERG) (HP:0000550)2.46742901
53Chromsome breakage (HP:0040012)2.46215355
54Tubular atrophy (HP:0000092)2.45617986
55Recurrent otitis media (HP:0000403)2.41777096
56Abnormality of midbrain morphology (HP:0002418)2.37667815
57Molar tooth sign on MRI (HP:0002419)2.37667815
58Intestinal atresia (HP:0011100)2.36305568
59Chromosomal breakage induced by crosslinking agents (HP:0003221)2.35840038
60Abnormality of macular pigmentation (HP:0008002)2.35052413
61Short ribs (HP:0000773)2.33697314
62Decreased central vision (HP:0007663)2.28867728
63Optic nerve hypoplasia (HP:0000609)2.27422627
64Genetic anticipation (HP:0003743)2.27084987
65Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.25251366
66Volvulus (HP:0002580)2.25060715
67Tubulointerstitial abnormality (HP:0001969)2.23941193
68Heterotopia (HP:0002282)2.22890338
69Breast carcinoma (HP:0003002)2.21754057
70Abnormality of alanine metabolism (HP:0010916)2.21465371
71Hyperalaninemia (HP:0003348)2.21465371
72Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.21465371
73Sclerocornea (HP:0000647)2.21096402
74Aplasia/Hypoplasia of the tibia (HP:0005772)2.19982227
75Congenital primary aphakia (HP:0007707)2.19590261
76Postaxial foot polydactyly (HP:0001830)2.18819298
77Gait imbalance (HP:0002141)2.18041299
78Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.15691766
79Aplasia/Hypoplasia of the tongue (HP:0010295)2.14053671
80Congenital sensorineural hearing impairment (HP:0008527)2.11913428
81Recurrent sinusitis (HP:0011108)2.10996724
82Absent frontal sinuses (HP:0002688)2.10630501
83Ectopic kidney (HP:0000086)2.07434737
84Hypoplasia of the capital femoral epiphysis (HP:0003090)2.04871821
85Increased corneal curvature (HP:0100692)2.04729191
86Keratoconus (HP:0000563)2.04729191
87Anencephaly (HP:0002323)2.04696429
88Facial cleft (HP:0002006)2.02163389
89Bile duct proliferation (HP:0001408)2.02066436
90Abnormal biliary tract physiology (HP:0012439)2.02066436
91Stage 5 chronic kidney disease (HP:0003774)2.02009785
92Genital tract atresia (HP:0001827)2.01323387
93Nephroblastoma (Wilms tumor) (HP:0002667)2.00940938
94Gastrointestinal atresia (HP:0002589)2.00680078
95Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.5922073
96Atrophy/Degeneration involving motor neurons (HP:0007373)1.99688192
97Polyuria (HP:0000103)1.98959798
98Oligodactyly (hands) (HP:0001180)1.98786928
99Ependymoma (HP:0002888)1.98493401
100Abnormality of chromosome stability (HP:0003220)1.98262788
101Microglossia (HP:0000171)1.95980210
102Aplasia/Hypoplasia of the uvula (HP:0010293)1.95834290
103Sloping forehead (HP:0000340)1.95401822
104Papillary thyroid carcinoma (HP:0002895)1.95139975
105Nephrogenic diabetes insipidus (HP:0009806)1.94685448
106Inability to walk (HP:0002540)1.92026163
107Horizontal nystagmus (HP:0000666)1.91547554
108Occipital encephalocele (HP:0002085)1.91437016
109Vaginal atresia (HP:0000148)1.90495836
110Poor coordination (HP:0002370)1.89854198
111Astigmatism (HP:0000483)1.89393984
112Prominent nose (HP:0000448)1.89370793
113Conjunctival telangiectasia (HP:0000524)1.87820361
114Preaxial hand polydactyly (HP:0001177)1.87692347
115Hypoplasia of the pons (HP:0012110)1.86227309
116Furrowed tongue (HP:0000221)1.86161913
117Embryonal renal neoplasm (HP:0011794)1.84110936
118Abnormality of the pons (HP:0007361)1.83148828
119Meckel diverticulum (HP:0002245)1.82359269
120Median cleft lip (HP:0000161)1.81134342
121Oculomotor apraxia (HP:0000657)1.79993661
122Large eyes (HP:0001090)1.79865768
123Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.79050460
124Lissencephaly (HP:0001339)1.77756343
125Decreased electroretinogram (ERG) amplitude (HP:0000654)1.76547164
1263-Methylglutaconic aciduria (HP:0003535)1.76322626
127Absent rod-and cone-mediated responses on ERG (HP:0007688)1.75626986
128Febrile seizures (HP:0002373)1.75408341
129Abnormality of DNA repair (HP:0003254)1.74599000
130Hyperkalemia (HP:0002153)1.74579724
131Abnormality of the duodenum (HP:0002246)1.74574677
132Small hand (HP:0200055)1.73185390
133Chorioretinal atrophy (HP:0000533)1.72437190
134Progressive inability to walk (HP:0002505)1.72225242
135Astrocytoma (HP:0009592)1.71976845
136Abnormality of the astrocytes (HP:0100707)1.71976845
137Renal dysplasia (HP:0000110)1.71896286
138Abnormal urine output (HP:0012590)1.71735069
139Abnormality of the preputium (HP:0100587)1.71115398
140Abnormality of the epiphyses of the hand (HP:0005924)1.70877639
141Methylmalonic acidemia (HP:0002912)1.70727754
142Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.70237580
143Absent epiphyses (HP:0010577)1.70237580
144Medial flaring of the eyebrow (HP:0010747)1.69949952
145Abnormality of the ileum (HP:0001549)1.69748209
146Abnormality of the labia minora (HP:0012880)1.69434011
147Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.68659995
148Congenital hepatic fibrosis (HP:0002612)1.68260648
149Recurrent bronchitis (HP:0002837)1.67419655
150Abnormality of ocular smooth pursuit (HP:0000617)1.65957134
151Short thorax (HP:0010306)1.63209326
152Abnormality of dentin (HP:0010299)1.61353376
153Sandal gap (HP:0001852)1.61011529
154Small intestinal stenosis (HP:0012848)1.57864511
155Duodenal stenosis (HP:0100867)1.57864511
156Truncal obesity (HP:0001956)1.57845710
157Abnormality of the carotid arteries (HP:0005344)1.56177047
158Medulloblastoma (HP:0002885)1.55670150
159Dislocated radial head (HP:0003083)1.55235851
160Decreased motor nerve conduction velocity (HP:0003431)1.53973348
161Postaxial hand polydactyly (HP:0001162)1.51373315
162Hypopigmentation of the fundus (HP:0007894)1.51090015
163Renovascular hypertension (HP:0100817)1.50784600
164Male pseudohermaphroditism (HP:0000037)1.49137153
165Abnormality of the renal cortex (HP:0011035)1.47401244
166Short humerus (HP:0005792)1.46637988
167Hypoplasia of the radius (HP:0002984)1.46080471
168Abnormality of the vasculature of the conjunctiva (HP:0008054)1.44804934
169Abnormality of the radial head (HP:0003995)1.44731666

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.00312074
2PDK48.00312074
3PDK25.16353693
4FRK5.13044814
5CDK123.36025301
6PNCK3.32823272
7CDC73.23357870
8INSRR3.03947433
9MAP4K22.93639989
10NEK22.69533544
11PRKD32.63807319
12TESK12.52606986
13PLK22.49168510
14NUAK12.42674277
15ZAK2.42274348
16ICK2.37384816
17ADRBK22.30957228
18WEE12.29694759
19PTK2B1.85016876
20TTK1.76105323
21TNIK1.75661750
22GRK11.70324515
23CASK1.66810978
24TRIM281.59444752
25OXSR11.55065307
26WNK41.48837253
27TLK11.44688141
28TAF11.39369564
29STK31.36556853
30ATR1.33605805
31TYRO31.29686594
32BRD41.29323743
33STK391.28377112
34PASK1.24538912
35CHEK11.20534543
36MAPK131.19726824
37PLK11.16743065
38CHEK21.15954106
39SRPK11.11959091
40TAOK31.05498558
41STK38L1.04577928
42WNK11.02908627
43EIF2AK31.01939710
44ATM0.97009169
45WNK30.96418428
46STK380.94860252
47PLK40.92078098
48BUB10.88992765
49CDK70.81898544
50PRKCG0.80310216
51PIK3CG0.80101764
52MTOR0.77463509
53PRKCE0.77116607
54CSNK1G20.76832651
55LATS10.76203500
56EEF2K0.74511688
57CSNK1G10.73821168
58MARK10.73601723
59DYRK30.73159337
60VRK20.72913456
61ADRBK10.68138089
62CDK90.67735556
63MST40.67171834
64CAMK1G0.65553004
65PAK30.65511007
66MAP3K40.65354724
67CCNB10.64767039
68ACVR1B0.64443291
69PLK30.64386974
70CSNK1G30.63398600
71ERBB30.62267682
72LATS20.60850539
73MAP2K70.60136150
74CDK40.59995689
75DYRK20.59505974
76CDK20.57681243
77BRSK20.56131262
78AURKB0.56059117
79MAP2K60.55822452
80MUSK0.54885207
81CSNK1A1L0.54327628
82TGFBR10.53852293
83CAMKK20.53363963
84FGFR20.53310363
85CDK190.50050851
86BCR0.49762023
87CAMK10.49001161
88CDK10.48640409
89PRKCI0.48608384
90NEK10.47092876
91EPHA40.45390867
92NTRK30.45207808
93MAPKAPK50.44900965
94STK40.44883166
95NLK0.44874921
96TIE10.44792528
97CSNK1D0.42746441
98DAPK20.41472973
99RPS6KA50.41106459
100STK160.40180146
101MAPK150.40025189
102CAMK2A0.39273992
103PRKG10.38623151
104EIF2AK10.38338570
105PDK10.38328884
106CSNK1A10.37744543
107MET0.36218622
108TXK0.35278306
109PRKDC0.34696684
110DYRK1B0.34321279
111PHKG20.34218544
112PHKG10.34218544
113EPHA20.33756244
114AURKA0.33496630
115SCYL20.32547745
116MKNK20.32534095
117PAK20.32331695
118PKN10.31294040
119CDK60.30143935
120FER0.29634041
121BRAF0.28985710
122CSNK1E0.28009588
123PINK10.26802869
124GSK3B0.26515993
125RPS6KB20.26099232
126PAK10.25836067
127CSNK2A20.25436809
128PRKAA10.25238600
129RPS6KB10.24496039
130PAK40.24412392
131MAPK140.22969624
132MKNK10.22779228
133MAPK100.21554817
134CAMK1D0.20880657
135MAP3K80.20279344
136MAPK10.18627134
137MARK30.18492970
138MELK0.17864506
139PAK60.17368929
140AKT30.16964141
141STK100.16154937
142CSNK2A10.15327126
143NEK60.14890389
144MAPK80.13952722
145BRSK10.13585942
146PIM10.12227491
147NTRK20.11765930
148AKT10.11592956
149TSSK60.09770728
150CDK30.09065028
151ALK0.08431086
152ERBB40.08392197
153VRK10.08294585
154PRKACB0.07923990
155RPS6KA30.06070382
156BMPR1B0.05003449
157TESK20.03905256

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034604.06776788
2Basal transcription factors_Homo sapiens_hsa030223.75059132
3RNA transport_Homo sapiens_hsa030133.49069422
4Dorso-ventral axis formation_Homo sapiens_hsa043203.36870674
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.08060295
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.01285903
7Homologous recombination_Homo sapiens_hsa034402.88576200
8mRNA surveillance pathway_Homo sapiens_hsa030152.81441845
9Vitamin B6 metabolism_Homo sapiens_hsa007502.77096463
10Selenocompound metabolism_Homo sapiens_hsa004502.73191369
11Pyruvate metabolism_Homo sapiens_hsa006202.68553372
12Cell cycle_Homo sapiens_hsa041102.68426306
13Phototransduction_Homo sapiens_hsa047442.68153100
14Oocyte meiosis_Homo sapiens_hsa041142.64360321
15Mismatch repair_Homo sapiens_hsa034302.48672111
16Butanoate metabolism_Homo sapiens_hsa006502.39648413
17Glycolysis / Gluconeogenesis_Homo sapiens_hsa000102.38196440
18DNA replication_Homo sapiens_hsa030302.19442571
19Spliceosome_Homo sapiens_hsa030402.16159378
20Ubiquitin mediated proteolysis_Homo sapiens_hsa041202.15485227
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.05914056
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.99558780
23Pentose phosphate pathway_Homo sapiens_hsa000301.97631548
24Maturity onset diabetes of the young_Homo sapiens_hsa049501.96524010
25Olfactory transduction_Homo sapiens_hsa047401.96101898
26Nitrogen metabolism_Homo sapiens_hsa009101.87893336
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.87832106
28Glucagon signaling pathway_Homo sapiens_hsa049221.87582559
29Nucleotide excision repair_Homo sapiens_hsa034201.82943889
30RNA degradation_Homo sapiens_hsa030181.81613868
31Nicotine addiction_Homo sapiens_hsa050331.81547355
32Fatty acid biosynthesis_Homo sapiens_hsa000611.72649956
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.69579343
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.67638036
35Non-homologous end-joining_Homo sapiens_hsa034501.61110946
36Protein export_Homo sapiens_hsa030601.58210038
37Antigen processing and presentation_Homo sapiens_hsa046121.57835176
38Taste transduction_Homo sapiens_hsa047421.56345843
39Tryptophan metabolism_Homo sapiens_hsa003801.55299763
40Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.53018810
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.49288496
42Propanoate metabolism_Homo sapiens_hsa006401.47630640
43Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.47260172
44p53 signaling pathway_Homo sapiens_hsa041151.44985898
45Oxidative phosphorylation_Homo sapiens_hsa001901.44171141
46Systemic lupus erythematosus_Homo sapiens_hsa053221.41838058
47Cysteine and methionine metabolism_Homo sapiens_hsa002701.41041797
48Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.23047680
49Regulation of autophagy_Homo sapiens_hsa041401.22788621
50RNA polymerase_Homo sapiens_hsa030201.21468167
51Base excision repair_Homo sapiens_hsa034101.20530219
52Primary bile acid biosynthesis_Homo sapiens_hsa001201.19883622
53alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.19117320
54Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.18335452
55Linoleic acid metabolism_Homo sapiens_hsa005911.17335874
56Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.11792997
57Parkinsons disease_Homo sapiens_hsa050121.11483077
58Morphine addiction_Homo sapiens_hsa050321.10718271
59Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.10534232
60Caffeine metabolism_Homo sapiens_hsa002321.09986362
61Huntingtons disease_Homo sapiens_hsa050161.09052483
62One carbon pool by folate_Homo sapiens_hsa006701.08309093
63Pyrimidine metabolism_Homo sapiens_hsa002401.06349445
64Viral carcinogenesis_Homo sapiens_hsa052031.04245891
65Purine metabolism_Homo sapiens_hsa002301.04142155
66Retinol metabolism_Homo sapiens_hsa008300.99726106
67Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.98607967
68Biosynthesis of amino acids_Homo sapiens_hsa012300.97887225
69Glycerolipid metabolism_Homo sapiens_hsa005610.95915623
70ABC transporters_Homo sapiens_hsa020100.92968952
71Steroid hormone biosynthesis_Homo sapiens_hsa001400.92841807
72Peroxisome_Homo sapiens_hsa041460.90367598
73Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.89876584
74Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.88656850
75Central carbon metabolism in cancer_Homo sapiens_hsa052300.88412788
76Carbon metabolism_Homo sapiens_hsa012000.85326866
77Chemical carcinogenesis_Homo sapiens_hsa052040.85188008
78Lysine degradation_Homo sapiens_hsa003100.84950230
79Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.84865145
80Epstein-Barr virus infection_Homo sapiens_hsa051690.82626578
81Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81958216
82Glutamatergic synapse_Homo sapiens_hsa047240.80171394
83Serotonergic synapse_Homo sapiens_hsa047260.79125187
84Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.78560794
85Circadian entrainment_Homo sapiens_hsa047130.77787074
86beta-Alanine metabolism_Homo sapiens_hsa004100.76195585
87Alcoholism_Homo sapiens_hsa050340.75920381
88Fatty acid degradation_Homo sapiens_hsa000710.75075252
89Insulin secretion_Homo sapiens_hsa049110.74254266
90GABAergic synapse_Homo sapiens_hsa047270.73668238
91Amphetamine addiction_Homo sapiens_hsa050310.73563625
92Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.73012643
93Calcium signaling pathway_Homo sapiens_hsa040200.71294097
94TGF-beta signaling pathway_Homo sapiens_hsa043500.71108164
95Cardiac muscle contraction_Homo sapiens_hsa042600.69610906
96Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.68836554
97Hedgehog signaling pathway_Homo sapiens_hsa043400.67684958
98Metabolic pathways_Homo sapiens_hsa011000.66923336
99HTLV-I infection_Homo sapiens_hsa051660.66361832
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.65859996
101Estrogen signaling pathway_Homo sapiens_hsa049150.65853704
102Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65426805
103Salivary secretion_Homo sapiens_hsa049700.64545030
104Basal cell carcinoma_Homo sapiens_hsa052170.62065443
105Proteasome_Homo sapiens_hsa030500.61669645
106Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.61297107
107Herpes simplex infection_Homo sapiens_hsa051680.59075246
108Circadian rhythm_Homo sapiens_hsa047100.58295816
109Sulfur relay system_Homo sapiens_hsa041220.57350090
110Alzheimers disease_Homo sapiens_hsa050100.56041141
111Thyroid hormone signaling pathway_Homo sapiens_hsa049190.55306748
112Long-term potentiation_Homo sapiens_hsa047200.53020825
113Wnt signaling pathway_Homo sapiens_hsa043100.51985272
114Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.51843442
115Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.51138841
116Adherens junction_Homo sapiens_hsa045200.51108310
117MicroRNAs in cancer_Homo sapiens_hsa052060.49910212
118Sulfur metabolism_Homo sapiens_hsa009200.48755267
119Tight junction_Homo sapiens_hsa045300.48360324
120Renin secretion_Homo sapiens_hsa049240.46135416
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.45680088
122Hippo signaling pathway_Homo sapiens_hsa043900.45333854
123Intestinal immune network for IgA production_Homo sapiens_hsa046720.44242375
124Arachidonic acid metabolism_Homo sapiens_hsa005900.43435281
125Ovarian steroidogenesis_Homo sapiens_hsa049130.42872598
126mTOR signaling pathway_Homo sapiens_hsa041500.42675106
127Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.42628935
128Inositol phosphate metabolism_Homo sapiens_hsa005620.41982730
129Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.40631206
130AMPK signaling pathway_Homo sapiens_hsa041520.39535360
131Small cell lung cancer_Homo sapiens_hsa052220.39270261
132Steroid biosynthesis_Homo sapiens_hsa001000.39185887
133Phosphatidylinositol signaling system_Homo sapiens_hsa040700.38731179
134VEGF signaling pathway_Homo sapiens_hsa043700.35869349
135Ether lipid metabolism_Homo sapiens_hsa005650.34075776
136PPAR signaling pathway_Homo sapiens_hsa033200.33509501
137Fructose and mannose metabolism_Homo sapiens_hsa000510.32641818
138Influenza A_Homo sapiens_hsa051640.32079875
139Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31868362
140Notch signaling pathway_Homo sapiens_hsa043300.31297665
141Fat digestion and absorption_Homo sapiens_hsa049750.28104868
142Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.25394296
143Legionellosis_Homo sapiens_hsa051340.25054967
144Longevity regulating pathway - mammal_Homo sapiens_hsa042110.24986138
145cGMP-PKG signaling pathway_Homo sapiens_hsa040220.23686636
146HIF-1 signaling pathway_Homo sapiens_hsa040660.23565315
147Prostate cancer_Homo sapiens_hsa052150.20235098
148Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.19281290
149N-Glycan biosynthesis_Homo sapiens_hsa005100.17240329
150Mineral absorption_Homo sapiens_hsa049780.16580877
151Thyroid cancer_Homo sapiens_hsa052160.16478587
152Fatty acid metabolism_Homo sapiens_hsa012120.11945758
153ECM-receptor interaction_Homo sapiens_hsa045120.11924667
154Transcriptional misregulation in cancer_Homo sapiens_hsa052020.11242360
155Protein digestion and absorption_Homo sapiens_hsa049740.10242021
156Pathways in cancer_Homo sapiens_hsa052000.09771724
157Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.09657458
158Colorectal cancer_Homo sapiens_hsa052100.08169189
159Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.08125365
160Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.08108467

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