MEIS3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a homeobox protein and probable transcriptional regulator. The orthologous protein in mouse controls expression of 3-phosphoinositide dependent protein kinase 1, which promotes survival of pancreatic beta-cells. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)6.33692372
2regulation of synaptic vesicle exocytosis (GO:2000300)4.83342178
3pyrimidine nucleobase catabolic process (GO:0006208)4.32945740
4regulation of vesicle fusion (GO:0031338)4.32410015
5protein localization to synapse (GO:0035418)4.32073726
6regulation of synaptic vesicle transport (GO:1902803)4.31583004
7negative regulation of oligodendrocyte differentiation (GO:0048715)4.26917863
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.11478143
9axonal fasciculation (GO:0007413)3.90402455
10regulation of short-term neuronal synaptic plasticity (GO:0048172)3.89228640
11synaptic vesicle exocytosis (GO:0016079)3.87957334
12synaptic vesicle maturation (GO:0016188)3.85500170
13cell migration in hindbrain (GO:0021535)3.84773755
14presynaptic membrane assembly (GO:0097105)3.84540647
15ionotropic glutamate receptor signaling pathway (GO:0035235)3.82130231
16vocalization behavior (GO:0071625)3.78709751
17neuron cell-cell adhesion (GO:0007158)3.75558274
18protein retention in ER lumen (GO:0006621)3.71387289
19neuron recognition (GO:0008038)3.69825378
20regulation of type B pancreatic cell apoptotic process (GO:2000674)3.62417901
21maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.56053702
22positive regulation of synapse maturation (GO:0090129)3.47546458
23postsynaptic membrane organization (GO:0001941)3.46661842
24regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.44996506
25positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.42033234
26regulation of neuronal synaptic plasticity (GO:0048168)3.36127837
27synaptic transmission, glutamatergic (GO:0035249)3.32837928
28glutamate receptor signaling pathway (GO:0007215)3.32300791
29central nervous system projection neuron axonogenesis (GO:0021952)3.30329287
30regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.30108835
31establishment of mitochondrion localization (GO:0051654)3.29642528
32regulation of synapse structural plasticity (GO:0051823)3.24054684
33dendrite morphogenesis (GO:0048813)3.23919043
34regulation of synapse maturation (GO:0090128)3.21676599
35nucleobase catabolic process (GO:0046113)3.14996580
36presynaptic membrane organization (GO:0097090)3.14851290
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.12279737
38cerebellar granule cell differentiation (GO:0021707)3.11242545
39cerebellar Purkinje cell differentiation (GO:0021702)3.09895557
40negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.09635749
41locomotory exploration behavior (GO:0035641)3.09538593
42positive regulation of synaptic transmission, GABAergic (GO:0032230)3.08373827
43synaptic vesicle endocytosis (GO:0048488)3.05895377
44regulation of glutamate receptor signaling pathway (GO:1900449)3.05022099
45neuronal ion channel clustering (GO:0045161)3.01100575
46cell communication by electrical coupling (GO:0010644)2.95569619
47positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.94232270
48substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.93570334
49substrate-independent telencephalic tangential migration (GO:0021826)2.93570334
50layer formation in cerebral cortex (GO:0021819)2.93530290
51glutamate secretion (GO:0014047)2.91895434
52hippocampus development (GO:0021766)2.91510089
53membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.89376197
54regulation of excitatory postsynaptic membrane potential (GO:0060079)2.86491110
55neuron projection extension (GO:1990138)2.85692216
56axon extension involved in axon guidance (GO:0048846)2.85580772
57neuron projection extension involved in neuron projection guidance (GO:1902284)2.85580772
58synaptic vesicle docking involved in exocytosis (GO:0016081)2.85272964
59mitochondrion transport along microtubule (GO:0047497)2.83274042
60establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.83274042
61exploration behavior (GO:0035640)2.82938082
62negative regulation of Notch signaling pathway (GO:0045746)2.80584751
63dendritic spine morphogenesis (GO:0060997)2.79505367
64regulation of respiratory system process (GO:0044065)2.79113249
65negative regulation of microtubule polymerization (GO:0031115)2.78281601
66regulation of postsynaptic membrane potential (GO:0060078)2.77839862
67neuromuscular process controlling balance (GO:0050885)2.75983724
68regulation of neurotransmitter secretion (GO:0046928)2.75982434
69positive regulation of dendritic spine morphogenesis (GO:0061003)2.74965105
70spinal cord development (GO:0021510)2.72692800
71neuron-neuron synaptic transmission (GO:0007270)2.72656984
72positive regulation of synapse assembly (GO:0051965)2.71793308
73neurotransmitter secretion (GO:0007269)2.71698568
74response to auditory stimulus (GO:0010996)2.71626792
75central nervous system neuron axonogenesis (GO:0021955)2.70901214
76negative regulation of synaptic transmission, GABAergic (GO:0032229)2.70367510
77negative regulation of osteoblast proliferation (GO:0033689)2.69230075
78cerebellum development (GO:0021549)2.66979579
79regulation of axon extension involved in axon guidance (GO:0048841)2.66615405
80regulation of axon guidance (GO:1902667)2.66119517
81planar cell polarity pathway involved in neural tube closure (GO:0090179)2.65923437
82cell-cell junction maintenance (GO:0045217)2.65190489
83positive regulation of axonogenesis (GO:0050772)2.64859277
84neuromuscular synaptic transmission (GO:0007274)2.64357631
85activation of protein kinase A activity (GO:0034199)2.63200652
86regulation of transcription involved in cell fate commitment (GO:0060850)2.63193131
87innervation (GO:0060384)2.60308476
88regulation of axonogenesis (GO:0050770)2.59264813
89insulin secretion (GO:0030073)2.57812171
90negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.57687564
91neuron migration (GO:0001764)2.56482554
92regulation of beta-amyloid formation (GO:1902003)2.56162772
93regulation of NFAT protein import into nucleus (GO:0051532)2.55977315
94nonmotile primary cilium assembly (GO:0035058)2.55646764
95negative regulation of axonogenesis (GO:0050771)2.53283845
96regulation of synapse assembly (GO:0051963)2.53115336
97G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.51622782
98positive regulation of membrane potential (GO:0045838)2.51165144
99regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.50720336
100neuronal action potential propagation (GO:0019227)2.50190101
101positive regulation of neurotransmitter transport (GO:0051590)2.49850719
102regulation of synapse organization (GO:0050807)2.49371118
103cerebral cortex radially oriented cell migration (GO:0021799)2.48463888
104positive regulation of dendritic spine development (GO:0060999)2.48413347
105regulation of long-term neuronal synaptic plasticity (GO:0048169)2.48283830
106long-term memory (GO:0007616)2.47685512
107synapse organization (GO:0050808)2.47555585
108regulation of amyloid precursor protein catabolic process (GO:1902991)2.47272107
109urinary tract smooth muscle contraction (GO:0014848)2.47258639
110calcium ion-dependent exocytosis (GO:0017156)2.47251276
111G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.46375257
112regulation of neurotransmitter transport (GO:0051588)2.45935509
113neurotransmitter-gated ion channel clustering (GO:0072578)2.45414158
114regulation of dendritic spine morphogenesis (GO:0061001)2.44712772
115cranial nerve morphogenesis (GO:0021602)2.44622733
116neurotransmitter transport (GO:0006836)2.43536740
117regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.43256415
118facial nerve structural organization (GO:0021612)2.43189092
119proximal/distal pattern formation (GO:0009954)2.42963912
120negative regulation of axon extension (GO:0030517)2.42346933
121mechanosensory behavior (GO:0007638)2.41786561
122startle response (GO:0001964)2.41594019
123positive regulation of dendrite development (GO:1900006)2.41278284
124positive T cell selection (GO:0043368)2.41074550
125transmission of nerve impulse (GO:0019226)2.40557597
126dendritic spine organization (GO:0097061)2.38655162
127regulation of dendrite morphogenesis (GO:0048814)2.38560891
128adult walking behavior (GO:0007628)2.38340372
129forebrain neuron differentiation (GO:0021879)2.38026784
130auditory behavior (GO:0031223)2.36721840
131learning (GO:0007612)2.36566017
132neuromuscular process (GO:0050905)2.36466265
133regulation of respiratory gaseous exchange (GO:0043576)2.36310539
134synapse assembly (GO:0007416)2.36098470
135membrane depolarization (GO:0051899)2.35937083
136axon extension (GO:0048675)2.35901892
137cerebellar Purkinje cell layer development (GO:0021680)2.34976053
138regulation of oligodendrocyte differentiation (GO:0048713)2.34759702

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.09284249
2GBX2_23144817_ChIP-Seq_PC3_Human3.43161144
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.41461782
4EZH2_27304074_Chip-Seq_ESCs_Mouse3.32860735
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.24321245
6JARID2_20075857_ChIP-Seq_MESCs_Mouse3.24265305
7CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons3.10098880
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.06003930
9EZH2_18974828_ChIP-Seq_MESCs_Mouse3.01387489
10RNF2_18974828_ChIP-Seq_MESCs_Mouse3.01387489
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.96325766
12* EZH2_27294783_Chip-Seq_ESCs_Mouse2.92114349
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.91747511
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.87520651
15SUZ12_27294783_Chip-Seq_ESCs_Mouse2.82935773
16IKZF1_21737484_ChIP-ChIP_HCT116_Human2.79025763
17SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.77818227
18* REST_21632747_ChIP-Seq_MESCs_Mouse2.65064258
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.62084350
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.58704929
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.39751401
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.29803284
23BMI1_23680149_ChIP-Seq_NPCS_Mouse2.24802267
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.20622967
25REST_18959480_ChIP-ChIP_MESCs_Mouse2.18089926
26PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.17141717
27CBX2_27304074_Chip-Seq_ESCs_Mouse2.12709855
28DROSHA_22980978_ChIP-Seq_HELA_Human2.03709898
29EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.02997632
30RARB_27405468_Chip-Seq_BRAIN_Mouse1.88736886
31RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.79952533
32TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.76112752
33* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.73975192
34TP53_20018659_ChIP-ChIP_R1E_Mouse1.69436988
35RING1B_27294783_Chip-Seq_ESCs_Mouse1.67578441
36ZFP281_18757296_ChIP-ChIP_E14_Mouse1.61133531
37ERG_21242973_ChIP-ChIP_JURKAT_Human1.59333222
38VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.57907903
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54371300
40RNF2_27304074_Chip-Seq_NSC_Mouse1.47511973
41SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.44763902
42ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.44177814
43IGF1R_20145208_ChIP-Seq_DFB_Human1.42797243
44ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.40761454
45RING1B_27294783_Chip-Seq_NPCs_Mouse1.39993729
46TRIM28_21343339_ChIP-Seq_HEK293_Human1.39118953
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.37089865
48DNAJC2_21179169_ChIP-ChIP_NT2_Human1.36923454
49STAT6_21828071_ChIP-Seq_BEAS2B_Human1.35511155
50CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.34245985
51TP63_19390658_ChIP-ChIP_HaCaT_Human1.32186851
52MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.31095167
53DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.28743421
54RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.22891723
55GATA1_26923725_Chip-Seq_HPCs_Mouse1.19840612
56WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.18919359
57KDM2B_26808549_Chip-Seq_K562_Human1.18702994
58* PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.16468352
59AR_21572438_ChIP-Seq_LNCaP_Human1.14633413
60ZNF274_21170338_ChIP-Seq_K562_Hela1.13250348
61ZFP57_27257070_Chip-Seq_ESCs_Mouse1.12275607
62AR_19668381_ChIP-Seq_PC3_Human1.11297130
63* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.09181164
64* ISL1_27105846_Chip-Seq_CPCs_Mouse1.08400716
65CTCF_27219007_Chip-Seq_Bcells_Human1.08340069
66P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05584563
67THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.03880400
68* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.03646841
69RBPJ_22232070_ChIP-Seq_NCS_Mouse1.03521902
70EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.03146075
71POU5F1_16153702_ChIP-ChIP_HESCs_Human1.02886774
72NR3C1_23031785_ChIP-Seq_PC12_Mouse1.02200837
73TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01666611
74TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.01134142
75ZFP281_27345836_Chip-Seq_ESCs_Mouse1.01000144
76P300_19829295_ChIP-Seq_ESCs_Human1.00818151
77CTBP1_25329375_ChIP-Seq_LNCAP_Human0.97903537
78MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96799163
79TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.94760517
80SMAD4_21799915_ChIP-Seq_A2780_Human0.94719244
81LXR_22292898_ChIP-Seq_THP-1_Human0.94692251
82AR_25329375_ChIP-Seq_VCAP_Human0.92348191
83CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91913613
84SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.91560247
85SOX2_21211035_ChIP-Seq_LN229_Gbm0.90562566
86DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.90061298
87SMAD3_21741376_ChIP-Seq_EPCs_Human0.88365202
88KDM2B_26808549_Chip-Seq_SUP-B15_Human0.88230235
89ARNT_22903824_ChIP-Seq_MCF-7_Human0.87954446
90YAP1_20516196_ChIP-Seq_MESCs_Mouse0.87820092
91TOP2B_26459242_ChIP-Seq_MCF-7_Human0.87625410
92RARG_19884340_ChIP-ChIP_MEFs_Mouse0.86494351
93SOX3_22085726_ChIP-Seq_NPCs_Mouse0.85912754
94TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.85825884
95SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.84754774
96* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.84517575
97WT1_25993318_ChIP-Seq_PODOCYTE_Human0.83984030
98* TET1_21490601_ChIP-Seq_MESCs_Mouse0.83331866
99TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.80922525
100SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.80607787
101KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.80211293
102GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78181259
103RUNX2_22187159_ChIP-Seq_PCA_Human0.77956372
104RUNX1_26923725_Chip-Seq_HPCs_Mouse0.77556248
105STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.76544344
106NR3C1_21868756_ChIP-Seq_MCF10A_Human0.76393615
107TP53_23651856_ChIP-Seq_MEFs_Mouse0.75799277
108WT1_19549856_ChIP-ChIP_CCG9911_Human0.75787507
109TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.75291973
110POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.75291973
111LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.75184883
112SMAD4_21741376_ChIP-Seq_HESCs_Human0.74783546
113MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.73445851
114PIAS1_25552417_ChIP-Seq_VCAP_Human0.73275083
115UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.73075895
116NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.72847626
117TP53_18474530_ChIP-ChIP_U2OS_Human0.72779206
118STAT3_23295773_ChIP-Seq_U87_Human0.72592143
119AHR_22903824_ChIP-Seq_MCF-7_Human0.71767804
120SMAD3_21741376_ChIP-Seq_ESCs_Human0.70589649
121OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.70062038

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.81842243
2MP0003880_abnormal_central_pattern3.36973620
3MP0005423_abnormal_somatic_nervous3.31548382
4MP0003122_maternal_imprinting3.13851771
5MP0003635_abnormal_synaptic_transmissio3.01566709
6MP0002909_abnormal_adrenal_gland2.54321909
7MP0006276_abnormal_autonomic_nervous2.49855577
8MP0005645_abnormal_hypothalamus_physiol2.45364267
9MP0002063_abnormal_learning/memory/cond2.45168483
10MP0010386_abnormal_urinary_bladder2.41979238
11MP0004270_analgesia2.40977532
12MP0009745_abnormal_behavioral_response2.31558882
13MP0000778_abnormal_nervous_system2.30292800
14MP0002733_abnormal_thermal_nociception2.27015220
15MP0002184_abnormal_innervation2.21234716
16MP0002064_seizures2.14252617
17MP0001968_abnormal_touch/_nociception2.08588899
18MP0003787_abnormal_imprinting2.02358566
19MP0001486_abnormal_startle_reflex1.95119672
20MP0002572_abnormal_emotion/affect_behav1.92817744
21MP0002638_abnormal_pupillary_reflex1.92534578
22MP0008961_abnormal_basal_metabolism1.91237480
23MP0001970_abnormal_pain_threshold1.87968732
24MP0003183_abnormal_peptide_metabolism1.85352636
25MP0002557_abnormal_social/conspecific_i1.83151157
26MP0002734_abnormal_mechanical_nocicepti1.81009273
27MP0002234_abnormal_pharynx_morphology1.77047246
28MP0004858_abnormal_nervous_system1.76909253
29MP0001984_abnormal_olfaction1.74004543
30MP0002736_abnormal_nociception_after1.73027023
31MP0004811_abnormal_neuron_physiology1.72946854
32MP0000955_abnormal_spinal_cord1.72253579
33MP0001502_abnormal_circadian_rhythm1.71519308
34MP0000678_abnormal_parathyroid_gland1.71298128
35MP0005646_abnormal_pituitary_gland1.71250413
36MP0002735_abnormal_chemical_nociception1.70779622
37MP0006292_abnormal_olfactory_placode1.69978795
38MP0003283_abnormal_digestive_organ1.69567829
39MP0009046_muscle_twitch1.61982529
40MP0005503_abnormal_tendon_morphology1.52471211
41MP0002067_abnormal_sensory_capabilities1.52088832
42MP0002272_abnormal_nervous_system1.50241680
43MP0002882_abnormal_neuron_morphology1.48293468
44MP0003121_genomic_imprinting1.48135815
45MP0005394_taste/olfaction_phenotype1.47733757
46MP0005499_abnormal_olfactory_system1.47733757
47MP0006072_abnormal_retinal_apoptosis1.45105948
48MP0000049_abnormal_middle_ear1.43611403
49MP0008438_abnormal_cutaneous_collagen1.43459869
50MP0001529_abnormal_vocalization1.40552586
51MP0000631_abnormal_neuroendocrine_gland1.40209533
52MP0002653_abnormal_ependyma_morphology1.39195675
53MP0002751_abnormal_autonomic_nervous1.38100723
54MP0001501_abnormal_sleep_pattern1.33499212
55MP0002693_abnormal_pancreas_physiology1.31751375
56MP0009780_abnormal_chondrocyte_physiolo1.31593381
57MP0005257_abnormal_intraocular_pressure1.30286392
58MP0008789_abnormal_olfactory_epithelium1.29595502
59MP0002249_abnormal_larynx_morphology1.28820737
60MP0000538_abnormal_urinary_bladder1.27809737
61MP0008569_lethality_at_weaning1.27037743
62MP0003303_peritoneal_inflammation1.25000882
63MP0003329_amyloid_beta_deposits1.24776089
64MP0001944_abnormal_pancreas_morphology1.22129761
65MP0001440_abnormal_grooming_behavior1.20353681
66MP0005623_abnormal_meninges_morphology1.18486850
67MP0001270_distended_abdomen1.18036376
68MP0003879_abnormal_hair_cell1.12834086
69MP0000566_synostosis1.12738847
70MP0005253_abnormal_eye_physiology1.10737463
71MP0008995_early_reproductive_senescence1.09387179
72MP0002152_abnormal_brain_morphology1.03748656
73MP0003942_abnormal_urinary_system1.02933557
74MP0001299_abnormal_eye_distance/1.02923670
75MP0000013_abnormal_adipose_tissue1.02376269
76MP0003123_paternal_imprinting1.02129112
77MP0002066_abnormal_motor_capabilities/c1.01192606
78MP0000534_abnormal_ureter_morphology0.99411707
79MP0005386_behavior/neurological_phenoty0.97997296
80MP0004924_abnormal_behavior0.97997296
81MP0002752_abnormal_somatic_nervous0.97094996
82MP0003937_abnormal_limbs/digits/tail_de0.95942394
83MP0002069_abnormal_eating/drinking_beha0.95499036
84MP0003119_abnormal_digestive_system0.95404317
85MP0002822_catalepsy0.95374261
86MP0005248_abnormal_Harderian_gland0.93804107
87MP0009250_abnormal_appendicular_skeleto0.93362476
88MP0004043_abnormal_pH_regulation0.91617110
89MP0005220_abnormal_exocrine_pancreas0.91478317
90MP0003861_abnormal_nervous_system0.91210625
91MP0001348_abnormal_lacrimal_gland0.90868372
92MP0001188_hyperpigmentation0.90397718
93MP0003634_abnormal_glial_cell0.88361891
94MP0000537_abnormal_urethra_morphology0.86383524
95MP0001177_atelectasis0.85959889
96MP0004510_myositis0.85681637
97MP0000462_abnormal_digestive_system0.85317281
98MP0005171_absent_coat_pigmentation0.85178409
99MP0003385_abnormal_body_wall0.84812867
100MP0002233_abnormal_nose_morphology0.84413626
101MP0009384_cardiac_valve_regurgitation0.83866552
102MP0003755_abnormal_palate_morphology0.83827928
103MP0003172_abnormal_lysosome_physiology0.82973057
104MP0000428_abnormal_craniofacial_morphol0.82609607
105MP0003136_yellow_coat_color0.82083117
106MP0004742_abnormal_vestibular_system0.81487623
107MP0000579_abnormal_nail_morphology0.80525706
108MP0010030_abnormal_orbit_morphology0.80098919
109MP0002697_abnormal_eye_size0.79911174
110MP0001958_emphysema0.78194976
111MP0003137_abnormal_impulse_conducting0.77309054
112MP0003705_abnormal_hypodermis_morpholog0.76649574
113MP0001986_abnormal_taste_sensitivity0.76393789
114MP0003633_abnormal_nervous_system0.76058805
115MP0001664_abnormal_digestion0.73679292
116MP0003938_abnormal_ear_development0.73624854
117MP0004142_abnormal_muscle_tone0.72034880
118MP0001905_abnormal_dopamine_level0.70559811
119MP0004133_heterotaxia0.70228712
120MP0003011_delayed_dark_adaptation0.69818327
121MP0005379_endocrine/exocrine_gland_phen0.69279824
122MP0005551_abnormal_eye_electrophysiolog0.68461690
123MP0000026_abnormal_inner_ear0.67540687
124MP0004885_abnormal_endolymph0.66063654
125MP0001963_abnormal_hearing_physiology0.65367270
126MP0002116_abnormal_craniofacial_bone0.64222759
127MP0002081_perinatal_lethality0.63188437
128MP0003890_abnormal_embryonic-extraembry0.63178068

Predicted human phenotypes

RankGene SetZ-score
1Large eyes (HP:0001090)5.29013726
2Amblyopia (HP:0000646)4.50132339
3Failure to thrive in infancy (HP:0001531)4.47924761
4Focal motor seizures (HP:0011153)4.11074917
5Myokymia (HP:0002411)3.72139373
6Broad distal phalanx of finger (HP:0009836)3.69309328
7Focal seizures (HP:0007359)3.54242605
8Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.45770204
9Esotropia (HP:0000565)3.40147670
10Congenital glaucoma (HP:0001087)3.27049369
11Agitation (HP:0000713)3.24373142
12Febrile seizures (HP:0002373)3.20560238
13Progressive cerebellar ataxia (HP:0002073)3.13948430
14Decreased circulating renin level (HP:0003351)3.13749445
15Abnormal eating behavior (HP:0100738)3.05277842
16Turricephaly (HP:0000262)2.99511613
17Polyphagia (HP:0002591)2.91415161
18Epileptic encephalopathy (HP:0200134)2.74474425
19Premature rupture of membranes (HP:0001788)2.74294620
20Hemiparesis (HP:0001269)2.70240215
21Abnormality of calcium-phosphate metabolism (HP:0100530)2.69522316
22Visual hallucinations (HP:0002367)2.68876775
23Absence seizures (HP:0002121)2.65590163
24Shallow orbits (HP:0000586)2.64810924
25Patent foramen ovale (HP:0001655)2.60961073
26Cortical dysplasia (HP:0002539)2.58916363
27Limb dystonia (HP:0002451)2.54123536
28Abnormality of the aortic arch (HP:0012303)2.46549186
29Torticollis (HP:0000473)2.45017119
30Supranuclear gaze palsy (HP:0000605)2.42471106
31Bowel diverticulosis (HP:0005222)2.39935495
32Abnormality of dentin (HP:0010299)2.39645145
33Broad metatarsal (HP:0001783)2.39077198
34Bladder diverticulum (HP:0000015)2.38537713
35Genetic anticipation (HP:0003743)2.35031074
36Prominent metopic ridge (HP:0005487)2.34218548
37Truncal ataxia (HP:0002078)2.33104365
38Generalized tonic-clonic seizures (HP:0002069)2.32759139
39Lissencephaly (HP:0001339)2.32119613
40Testicular neoplasm (HP:0010788)2.31287912
41Dialeptic seizures (HP:0011146)2.28142118
42Abnormality of the metopic suture (HP:0005556)2.27097571
43Generalized hypotonia (HP:0001290)2.26388546
44Congenital sensorineural hearing impairment (HP:0008527)2.26046853
45Mutism (HP:0002300)2.20217483
46Atonic seizures (HP:0010819)2.17679700
47Neonatal short-limb short stature (HP:0008921)2.16845028
48Aplasia involving bones of the extremities (HP:0009825)2.16582234
49Aplasia involving bones of the upper limbs (HP:0009823)2.16582234
50Aplasia of the phalanges of the hand (HP:0009802)2.16582234
51Hypoventilation (HP:0002791)2.15480554
52Ankle clonus (HP:0011448)2.15384143
53Protrusio acetabuli (HP:0003179)2.14298708
54Overriding aorta (HP:0002623)2.13716618
55Aplasia/Hypoplasia of the lens (HP:0008063)2.13223023
56Gait imbalance (HP:0002141)2.12336914
57Renovascular hypertension (HP:0100817)2.12088355
58Depression (HP:0000716)2.12084383
59Drooling (HP:0002307)2.09844055
60Excessive salivation (HP:0003781)2.09844055
61Abnormality of the lower motor neuron (HP:0002366)2.09181369
62Hyperacusis (HP:0010780)2.09161023
63Cutaneous finger syndactyly (HP:0010554)2.09074134
64Insomnia (HP:0100785)2.08694595
65Hypoplasia of the brainstem (HP:0002365)2.08336330
66Aplasia/Hypoplasia of the brainstem (HP:0007362)2.08336330
67Hypothermia (HP:0002045)2.07956040
68Coronal craniosynostosis (HP:0004440)2.07667759
69Aplasia/Hypoplasia of the sacrum (HP:0008517)2.06140243
70Megalencephaly (HP:0001355)2.05908342
71Renal duplication (HP:0000075)2.04058609
72Epileptiform EEG discharges (HP:0011182)1.99212437
73Elfin facies (HP:0004428)1.96636316
74Split foot (HP:0001839)1.96477045
75Soft skin (HP:0000977)1.95075650
76Focal dystonia (HP:0004373)1.94829454
77Exotropia (HP:0000577)1.93619025
78Retinal dysplasia (HP:0007973)1.93228530
79Progressive sensorineural hearing impairment (HP:0000408)1.92929296
80Cutaneous syndactyly (HP:0012725)1.90558235
81Unilateral renal agenesis (HP:0000122)1.89119185
82Stereotypic behavior (HP:0000733)1.89108978
83Vitreoretinal degeneration (HP:0000655)1.88596777
84EEG with generalized epileptiform discharges (HP:0011198)1.86737269
85Specific learning disability (HP:0001328)1.85370137
86Genu recurvatum (HP:0002816)1.85307616
87Deep palmar crease (HP:0006191)1.85245894
88Broad-based gait (HP:0002136)1.83218196
89Bronchomalacia (HP:0002780)1.81765552
90Congenital primary aphakia (HP:0007707)1.80084456
91Hypercortisolism (HP:0001578)1.79631257
92Abnormal EKG (HP:0003115)1.78865217
93Anxiety (HP:0000739)1.78630116
94Obstructive sleep apnea (HP:0002870)1.78593451
95Wide anterior fontanel (HP:0000260)1.77906102
96Spastic gait (HP:0002064)1.77884985
97Shawl scrotum (HP:0000049)1.77724156
98Craniofacial dystonia (HP:0012179)1.77184671
99Ankle contracture (HP:0006466)1.76432885
100Congenital malformation of the right heart (HP:0011723)1.76289904
101Double outlet right ventricle (HP:0001719)1.76289904
102Urinary bladder sphincter dysfunction (HP:0002839)1.75678998
103Atelectasis (HP:0100750)1.75551502
104Abnormal pancreas size (HP:0012094)1.74071881
105Sleep apnea (HP:0010535)1.72637833
106Neurofibrillary tangles (HP:0002185)1.71647044
107Apathy (HP:0000741)1.70362355
108Poor eye contact (HP:0000817)1.70120627
109Medial flaring of the eyebrow (HP:0010747)1.68996035
110Atrophic scars (HP:0001075)1.68292685
111Buphthalmos (HP:0000557)1.67492209
112Aqueductal stenosis (HP:0002410)1.67179803
113Diminished motivation (HP:0000745)1.66783345
114Spinal canal stenosis (HP:0003416)1.66201371
115Gastrointestinal infarctions (HP:0005244)1.66049821
116Maternal diabetes (HP:0009800)1.65979029
117Short 4th metacarpal (HP:0010044)1.65355648
118Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.65355648
119Action tremor (HP:0002345)1.64878145
120Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.64284598
121Absent speech (HP:0001344)1.64152733
122Mild short stature (HP:0003502)1.63156164
123Nephrogenic diabetes insipidus (HP:0009806)1.63001876
124Oligodactyly (hands) (HP:0001180)1.62984072
125Vascular tortuosity (HP:0004948)1.62385972
126Webbed neck (HP:0000465)1.61458839
127Partial duplication of the phalanx of hand (HP:0009999)1.60989110
128Infantile muscular hypotonia (HP:0008947)1.60432908
129Cortical visual impairment (HP:0100704)1.58890275
130Bell-shaped thorax (HP:0001591)1.58810221
131Septo-optic dysplasia (HP:0100842)1.58564734
132Hypsarrhythmia (HP:0002521)1.58096647
133Ulnar bowing (HP:0003031)1.58086145
134Deviation of the hallux (HP:0010051)1.57669226
135Trigonocephaly (HP:0000243)1.57472760
136Annular pancreas (HP:0001734)1.57310470
137Abnormality of the diencephalon (HP:0010662)1.56868175
138Autism (HP:0000717)1.56258155
139Sex reversal (HP:0012245)1.55812627
140Abnormal sex determination (HP:0012244)1.55812627
141Menstrual irregularities (HP:0000858)1.55480330
142Partial duplication of thumb phalanx (HP:0009944)1.55073346
143Dilatation of the ascending aorta (HP:0005111)1.54687180
144Narrow nasal bridge (HP:0000446)1.54651685
145Flat cornea (HP:0007720)1.54212493
146Restlessness (HP:0000711)1.53693445
147Pointed chin (HP:0000307)1.53529295
148Hyperextensible skin (HP:0000974)1.53365920
149Anophthalmia (HP:0000528)1.53228172
150Abnormality of the labia minora (HP:0012880)1.53163822
151Hallux valgus (HP:0001822)1.52554301
152Pachygyria (HP:0001302)1.52462390
153Abnormality of the intervertebral disk (HP:0005108)1.52395258
154Arnold-Chiari malformation (HP:0002308)1.52140926
155Type II lissencephaly (HP:0007260)1.52080890
156Aortic dissection (HP:0002647)1.52043579
157Hyperparathyroidism (HP:0000843)1.51751956
158Megalocornea (HP:0000485)1.51413459
159Impaired smooth pursuit (HP:0007772)1.51211634
160Long palpebral fissure (HP:0000637)1.50537504
161Morphological abnormality of the middle ear (HP:0008609)1.49548406
162Left ventricular hypertrophy (HP:0001712)1.49275093
163Open mouth (HP:0000194)1.48351385
164Impaired vibration sensation in the lower limbs (HP:0002166)1.46080105
165Meningocele (HP:0002435)1.45805956
166Tented upper lip vermilion (HP:0010804)1.44931697
167Growth hormone deficiency (HP:0000824)1.44730426

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP2K73.59751852
2NTRK33.45825587
3MARK13.39815177
4SIK33.10125870
5MAP3K122.74910101
6MAP3K42.70467217
7MAP3K92.45281373
8EPHA42.35173207
9EPHA32.26479375
10BRD42.20767337
11MAPK132.19359169
12KSR12.16758942
13NTRK22.15659919
14MINK12.01803269
15IRAK21.95193799
16PRKD31.90053643
17DYRK21.72426056
18MAP3K21.72045307
19UHMK11.70005705
20MAP2K41.66314201
21INSRR1.64646159
22LATS21.63509167
23WNK31.61700232
24FGFR21.61242259
25TNIK1.55437965
26DDR21.50728595
27MARK21.47389151
28ERBB31.47083206
29PAK61.45271730
30CASK1.40028652
31CAMKK21.30199746
32SIK21.25460261
33CDK51.22106232
34RPS6KA21.18236751
35BCR1.17269463
36TXK1.15259584
37IRAK41.14277681
38IRAK11.13667646
39PNCK1.13331431
40CSNK1G21.12608839
41DYRK1A1.12593442
42PRPF4B1.05947793
43PDGFRA1.03245978
44CAMK11.02226298
45PAK31.00601672
46PKN10.94826536
47TNK20.93015132
48CSNK1G30.91074733
49LIMK10.90345454
50CSNK1A1L0.90103993
51NTRK10.89850912
52PINK10.87744100
53TESK10.87430101
54RIPK40.86933912
55STK380.86410670
56MAPK150.86117027
57CAMKK10.85213218
58TESK20.84737459
59PRKCH0.81791056
60CAMK1G0.75930820
61DAPK20.75921865
62KSR20.75863671
63BMX0.75110061
64TRIB30.74772442
65PRKCZ0.72916901
66PRKCG0.72568398
67CSNK1G10.72344754
68ACVR1B0.72138377
69CDC42BPA0.71056557
70FES0.69633948
71DAPK10.69529887
72PHKG20.67709968
73PHKG10.67709968
74ARAF0.67384726
75CDK180.66726767
76MAP3K10.62932793
77PAK20.62676122
78CAMK2G0.62228534
79SGK4940.61498958
80SGK2230.61498958
81BRSK10.61384979
82GRK50.58764015
83PLK20.58380911
84ROCK20.58323917
85ROCK10.57976318
86HIPK20.56701053
87MAP3K60.54793798
88CDK140.53785806
89PRKCE0.53562728
90CDK150.52354609
91FER0.52081703
92ICK0.51939210
93ERBB20.51606219
94PASK0.51420430
95BMPR20.51295611
96EPHB20.51151961
97DYRK1B0.50801950
98DAPK30.47321687
99CAMK2B0.46974924
100CDK11A0.46946583
101MAPK90.45135132
102MAPK100.43901214
103CAMK2A0.43006136
104FYN0.42683354
105STK110.42356452
106BRAF0.42322845
107ITK0.41229356
108CAMK40.40377832
109SGK10.40059769
110MAPK80.38790275
111CDK190.38656323
112CAMK2D0.38639690
113MTOR0.38474985
114PTK20.37771278
115ADRBK10.37722511
116BMPR1B0.37084453
117PRKD20.36977569
118HCK0.36687684
119TAOK20.35830168
120RET0.35097264
121CSNK1D0.34908965
122RIPK10.34797078
123CSNK1E0.33848807
124MARK30.33541276
125FGFR10.33509038
126WNK40.33441311
127TYRO30.33377112
128SIK10.33265290
129YES10.32954755
130ERN10.32934047
131RPS6KA30.32748135
132GSK3B0.32512693
133PKN20.32302607
134SGK20.32285915
135PDGFRB0.30318929
136ERBB40.29468410

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047212.56387254
2Nicotine addiction_Homo sapiens_hsa050332.53224340
3Insulin secretion_Homo sapiens_hsa049112.26192185
4Circadian entrainment_Homo sapiens_hsa047132.11237018
5Maturity onset diabetes of the young_Homo sapiens_hsa049502.08193428
6GABAergic synapse_Homo sapiens_hsa047271.89015297
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.87906542
8Morphine addiction_Homo sapiens_hsa050321.86588982
9Glutamatergic synapse_Homo sapiens_hsa047241.86273544
10Cholinergic synapse_Homo sapiens_hsa047251.70546121
11Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.67563256
12Amphetamine addiction_Homo sapiens_hsa050311.66835423
13Dopaminergic synapse_Homo sapiens_hsa047281.66595718
14Long-term potentiation_Homo sapiens_hsa047201.63984953
15Olfactory transduction_Homo sapiens_hsa047401.63608580
16Basal cell carcinoma_Homo sapiens_hsa052171.63463416
17Hedgehog signaling pathway_Homo sapiens_hsa043401.62329811
18Cocaine addiction_Homo sapiens_hsa050301.60324192
19Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.55633622
20Type II diabetes mellitus_Homo sapiens_hsa049301.54519133
21Hippo signaling pathway_Homo sapiens_hsa043901.52287282
22Type I diabetes mellitus_Homo sapiens_hsa049401.51821066
23Axon guidance_Homo sapiens_hsa043601.51133979
24Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.48034569
25Vibrio cholerae infection_Homo sapiens_hsa051101.46083183
26Taste transduction_Homo sapiens_hsa047421.41336558
27Gap junction_Homo sapiens_hsa045401.37125018
28Serotonergic synapse_Homo sapiens_hsa047261.35728002
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.32189919
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.31618842
31GnRH signaling pathway_Homo sapiens_hsa049121.27802600
32Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.26819720
33Salivary secretion_Homo sapiens_hsa049701.26234928
34Vitamin B6 metabolism_Homo sapiens_hsa007501.19451072
35ECM-receptor interaction_Homo sapiens_hsa045121.18313729
36Oxytocin signaling pathway_Homo sapiens_hsa049211.17916350
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.16302878
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.11551710
39Collecting duct acid secretion_Homo sapiens_hsa049661.10559247
40Long-term depression_Homo sapiens_hsa047301.10387449
41Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.09593403
42Phototransduction_Homo sapiens_hsa047441.08316762
43Colorectal cancer_Homo sapiens_hsa052101.07165823
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06766208
45Neurotrophin signaling pathway_Homo sapiens_hsa047221.05595590
46Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.04001795
47ErbB signaling pathway_Homo sapiens_hsa040120.96930914
48Renin secretion_Homo sapiens_hsa049240.95937275
49Gastric acid secretion_Homo sapiens_hsa049710.93897202
50Alcoholism_Homo sapiens_hsa050340.92064501
51Calcium signaling pathway_Homo sapiens_hsa040200.89580389
52Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.89077663
53Tight junction_Homo sapiens_hsa045300.89048895
54cAMP signaling pathway_Homo sapiens_hsa040240.88204339
55Prion diseases_Homo sapiens_hsa050200.87963293
56Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.87027868
57Melanogenesis_Homo sapiens_hsa049160.86806970
58Protein digestion and absorption_Homo sapiens_hsa049740.86228271
59Glioma_Homo sapiens_hsa052140.84494955
60Endometrial cancer_Homo sapiens_hsa052130.84153755
61Estrogen signaling pathway_Homo sapiens_hsa049150.83817452
62Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.83416685
63Prolactin signaling pathway_Homo sapiens_hsa049170.82979673
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82745633
65T cell receptor signaling pathway_Homo sapiens_hsa046600.81639551
66Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.80540502
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.80137444
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.80054621
69Focal adhesion_Homo sapiens_hsa045100.78322550
70Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.78120511
71Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78056507
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.75114804
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74112295
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.73827560
75Pancreatic secretion_Homo sapiens_hsa049720.73413375
76Notch signaling pathway_Homo sapiens_hsa043300.73207846
77Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.70995865
78cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70753092
79Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.70691680
80Sulfur relay system_Homo sapiens_hsa041220.69716788
81Choline metabolism in cancer_Homo sapiens_hsa052310.68556689
82Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.68397436
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.68237008
84MAPK signaling pathway_Homo sapiens_hsa040100.67388202
85Circadian rhythm_Homo sapiens_hsa047100.67269912
86Rheumatoid arthritis_Homo sapiens_hsa053230.66281130
87SNARE interactions in vesicular transport_Homo sapiens_hsa041300.65898967
88Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.65680186
89Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64950592
90Thyroid hormone synthesis_Homo sapiens_hsa049180.63744790
91Phagosome_Homo sapiens_hsa041450.63683225
92Thyroid hormone signaling pathway_Homo sapiens_hsa049190.63183762
93Wnt signaling pathway_Homo sapiens_hsa043100.63069064
94Rap1 signaling pathway_Homo sapiens_hsa040150.61388822
95VEGF signaling pathway_Homo sapiens_hsa043700.60819719
96Oocyte meiosis_Homo sapiens_hsa041140.60389848
97Chemokine signaling pathway_Homo sapiens_hsa040620.60062831
98Ras signaling pathway_Homo sapiens_hsa040140.58786868
99N-Glycan biosynthesis_Homo sapiens_hsa005100.57650491
100Adherens junction_Homo sapiens_hsa045200.57419451
101Dilated cardiomyopathy_Homo sapiens_hsa054140.56880916
102Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56387670
103Graft-versus-host disease_Homo sapiens_hsa053320.52161072
104AMPK signaling pathway_Homo sapiens_hsa041520.51376118
105Non-small cell lung cancer_Homo sapiens_hsa052230.51085271
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50662623
107Salmonella infection_Homo sapiens_hsa051320.50480800
108Sphingolipid signaling pathway_Homo sapiens_hsa040710.49884007
109Lysosome_Homo sapiens_hsa041420.49830189
110Glucagon signaling pathway_Homo sapiens_hsa049220.48119657
111Allograft rejection_Homo sapiens_hsa053300.48001040
112Renal cell carcinoma_Homo sapiens_hsa052110.47761758
113Glycosaminoglycan degradation_Homo sapiens_hsa005310.46857324
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46785961
115Regulation of autophagy_Homo sapiens_hsa041400.45694657
116Endocytosis_Homo sapiens_hsa041440.45043643
117mTOR signaling pathway_Homo sapiens_hsa041500.43703200
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43451923
119Melanoma_Homo sapiens_hsa052180.42660830
120Cardiac muscle contraction_Homo sapiens_hsa042600.42462887
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42071625
122Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41981528
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.41566498
124Autoimmune thyroid disease_Homo sapiens_hsa053200.40901837
125PI3K-Akt signaling pathway_Homo sapiens_hsa041510.40782844
126Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40644628
127Chronic myeloid leukemia_Homo sapiens_hsa052200.40149533
128Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.40140763
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.39872699
130Central carbon metabolism in cancer_Homo sapiens_hsa052300.39580200
131Proteoglycans in cancer_Homo sapiens_hsa052050.39026883
132Bile secretion_Homo sapiens_hsa049760.38019269
133Regulation of actin cytoskeleton_Homo sapiens_hsa048100.37641130
134TGF-beta signaling pathway_Homo sapiens_hsa043500.37597941

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