MEP1A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1aminoglycoside antibiotic metabolic process (GO:0030647)8.95745910
2drug transport (GO:0015893)8.69390689
3regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)8.67221363
4lysine catabolic process (GO:0006554)8.46726050
5lysine metabolic process (GO:0006553)8.46726050
6organic cation transport (GO:0015695)8.19334391
7phosphate ion transport (GO:0006817)7.79380394
8regulation of guanylate cyclase activity (GO:0031282)7.62260427
9lipoprotein transport (GO:0042953)6.99936222
10intestinal absorption (GO:0050892)6.79535669
11phosphate ion transmembrane transport (GO:0035435)6.74381558
12cysteine metabolic process (GO:0006534)6.62146457
13epoxygenase P450 pathway (GO:0019373)6.59824393
14quaternary ammonium group transport (GO:0015697)6.42731387
15fat-soluble vitamin biosynthetic process (GO:0042362)6.40769123
16drug catabolic process (GO:0042737)6.40043539
17glyoxylate metabolic process (GO:0046487)6.12413924
18exogenous drug catabolic process (GO:0042738)5.98135698
19regulation of bile acid biosynthetic process (GO:0070857)5.96034328
20excretion (GO:0007588)5.93148947
21response to mercury ion (GO:0046689)5.83646527
22nonribosomal peptide biosynthetic process (GO:0019184)5.79661887
23positive regulation of guanylate cyclase activity (GO:0031284)5.75625353
24renal absorption (GO:0070293)5.74699266
25aspartate family amino acid catabolic process (GO:0009068)5.52026918
26tricarboxylic acid metabolic process (GO:0072350)5.51489710
27regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)5.49717173
28endocrine process (GO:0050886)5.49717173
29regulation of systemic arterial blood pressure by hormone (GO:0001990)5.49717173
30hormone catabolic process (GO:0042447)5.44603566
31short-chain fatty acid metabolic process (GO:0046459)5.31232793
32glutathione biosynthetic process (GO:0006750)5.30722353
33vitamin D metabolic process (GO:0042359)5.20746898
34homocysteine metabolic process (GO:0050667)5.19177691
35metanephric nephron tubule development (GO:0072234)5.13989123
36metanephric tubule development (GO:0072170)5.13989123
37toxin transport (GO:1901998)5.08524472
38modified amino acid transport (GO:0072337)5.06519171
39regulation of cellular extravasation (GO:0002691)4.96944999
40very-low-density lipoprotein particle assembly (GO:0034379)4.96864696
41regulation of systemic arterial blood pressure (GO:0003073)4.96400967
42branched-chain amino acid metabolic process (GO:0009081)4.88843387
43diacylglycerol metabolic process (GO:0046339)4.88781143
44carnitine transport (GO:0015879)4.87463711
45amino-acid betaine transport (GO:0015838)4.87463711
46virion attachment to host cell (GO:0019062)4.81806465
47adhesion of symbiont to host cell (GO:0044650)4.81806465
48valine metabolic process (GO:0006573)4.80820132
49indole-containing compound catabolic process (GO:0042436)4.79606435
50indolalkylamine catabolic process (GO:0046218)4.79606435
51tryptophan catabolic process (GO:0006569)4.79606435
52regulation of triglyceride catabolic process (GO:0010896)4.74758222
53receptor guanylyl cyclase signaling pathway (GO:0007168)4.74202433
54metanephric nephron epithelium development (GO:0072243)4.71132093
552-oxoglutarate metabolic process (GO:0006103)4.70704954
56trivalent inorganic anion homeostasis (GO:0072506)4.69847336
57phosphate ion homeostasis (GO:0055062)4.69847336
58fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.69293321
59aromatic amino acid family catabolic process (GO:0009074)4.65289334
60cellular glucuronidation (GO:0052695)4.62979748
61regulation of cGMP biosynthetic process (GO:0030826)4.62512539
62uronic acid metabolic process (GO:0006063)4.57177020
63glucuronate metabolic process (GO:0019585)4.57177020
64plasma lipoprotein particle assembly (GO:0034377)4.55823393
65tryptophan metabolic process (GO:0006568)4.50540420
66peptide hormone processing (GO:0016486)4.45090854
67L-phenylalanine metabolic process (GO:0006558)4.42667098
68erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.42667098
69bile acid and bile salt transport (GO:0015721)4.36635299
70urea cycle (GO:0000050)4.36313056
71renal system process involved in regulation of blood volume (GO:0001977)4.36151842
72amino-acid betaine metabolic process (GO:0006577)4.36111338
73cellular modified amino acid catabolic process (GO:0042219)4.34078160
74L-phenylalanine catabolic process (GO:0006559)4.33679063
75erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.33679063
76metanephric epithelium development (GO:0072207)4.29312584
77fatty acid beta-oxidation (GO:0006635)4.29280740
78glycoside metabolic process (GO:0016137)4.23510371
79fructose metabolic process (GO:0006000)4.22883912
80serine family amino acid metabolic process (GO:0009069)4.22383556
81response to phenylpropanoid (GO:0080184)4.21849789
82peptide biosynthetic process (GO:0043043)4.21317570
83serine family amino acid catabolic process (GO:0009071)4.20774116
84cellular ketone body metabolic process (GO:0046950)4.19700930
85proline metabolic process (GO:0006560)4.18192086
86urea metabolic process (GO:0019627)4.17872653
87peptide catabolic process (GO:0043171)4.17811653
88protein-lipid complex assembly (GO:0065005)4.16325051
89regulation of vitamin metabolic process (GO:0030656)4.14130618
90adhesion of symbiont to host (GO:0044406)4.11985924
91acetyl-CoA metabolic process (GO:0006084)4.09230531
92carnitine metabolic process (GO:0009437)4.05234934
93glycolipid catabolic process (GO:0019377)4.03910741
94glycosphingolipid catabolic process (GO:0046479)4.01554796
95nephron tubule development (GO:0072080)4.00243896
96maintenance of gastrointestinal epithelium (GO:0030277)3.99822574
97fatty acid oxidation (GO:0019395)3.99708548
98antibacterial humoral response (GO:0019731)3.97589716
99branched-chain amino acid catabolic process (GO:0009083)3.94125182
100lipid oxidation (GO:0034440)3.91893610
101glutamate metabolic process (GO:0006536)3.91566523
102antimicrobial humoral response (GO:0019730)3.86855791
103vitamin A metabolic process (GO:0006776)3.86612366
104vitamin transmembrane transport (GO:0035461)3.85764569
105oligosaccharide catabolic process (GO:0009313)3.84614859
106nitrogen cycle metabolic process (GO:0071941)3.84396865
107kynurenine metabolic process (GO:0070189)3.84366238
108regulation of cGMP metabolic process (GO:0030823)3.83643900
109vitamin transport (GO:0051180)3.82721936
110sulfur compound transport (GO:0072348)3.81696580
111cellular response to nitric oxide (GO:0071732)3.81029184
112sulfur amino acid catabolic process (GO:0000098)3.76232793
113phospholipid efflux (GO:0033700)3.74948192
114lipoprotein metabolic process (GO:0042157)3.73806035
115positive regulation of pseudopodium assembly (GO:0031274)3.72992389
116polyol transport (GO:0015791)3.72404428
117NADH metabolic process (GO:0006734)3.67192677
118* digestion (GO:0007586)3.66101043
119alkaloid metabolic process (GO:0009820)3.63124171
120drinking behavior (GO:0042756)3.62313595
121regulation of cholesterol esterification (GO:0010872)3.60908931
122ketone body metabolic process (GO:1902224)3.60826390
123glutathione metabolic process (GO:0006749)3.59069988
124renal tubule development (GO:0061326)3.57008605
125response to growth hormone (GO:0060416)3.56733647
126fatty acid catabolic process (GO:0009062)3.54727323
127glutamine family amino acid biosynthetic process (GO:0009084)3.52795508
128cellular amino acid catabolic process (GO:0009063)3.52649954
129fat-soluble vitamin metabolic process (GO:0006775)3.50541481
130positive regulation of glycoprotein biosynthetic process (GO:0010560)3.46733391
131glutathione derivative metabolic process (GO:1901685)3.46516323
132glutathione derivative biosynthetic process (GO:1901687)3.46516323
133serine family amino acid biosynthetic process (GO:0009070)3.45259020
134aromatic amino acid family metabolic process (GO:0009072)3.41874288
135cGMP-mediated signaling (GO:0019934)3.39874547
136phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.38771012
137indole-containing compound metabolic process (GO:0042430)3.38659136
138alpha-amino acid catabolic process (GO:1901606)3.35552083
139drug metabolic process (GO:0017144)3.34603688
140transepithelial transport (GO:0070633)3.34378162
141response to nitric oxide (GO:0071731)3.34320795
142indolalkylamine metabolic process (GO:0006586)3.33994212
143regulation of pseudopodium assembly (GO:0031272)3.33544036
144digestive system process (GO:0022600)3.33258555
145sulfate transmembrane transport (GO:1902358)3.33083088
146positive regulation of lipid catabolic process (GO:0050996)3.32729043
147flavonoid metabolic process (GO:0009812)3.32023927
148positive regulation of cGMP biosynthetic process (GO:0030828)3.31805111
149cellular response to reactive nitrogen species (GO:1902170)3.31791958
150sodium ion transport (GO:0006814)3.31248984
151positive regulation of lipoprotein lipase activity (GO:0051006)3.30220502
152positive regulation of triglyceride lipase activity (GO:0061365)3.30220502
153nucleoside diphosphate biosynthetic process (GO:0009133)3.28738588
154bile acid metabolic process (GO:0008206)3.28085443
155monocarboxylic acid catabolic process (GO:0072329)3.27532267
156antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.27273837
157regulation of cholesterol homeostasis (GO:2000188)3.26178352
158benzene-containing compound metabolic process (GO:0042537)3.25531156
159organic acid catabolic process (GO:0016054)3.24909585
160carboxylic acid catabolic process (GO:0046395)3.24909585
161cGMP biosynthetic process (GO:0006182)3.23962659
162ceramide catabolic process (GO:0046514)3.22862851
163sexual reproduction (GO:0019953)3.21773207
164succinate metabolic process (GO:0006105)3.21618164
165sodium-independent organic anion transport (GO:0043252)3.21478289
166nephron epithelium development (GO:0072009)3.21042047
167arginine metabolic process (GO:0006525)3.19260159
168glycosylceramide metabolic process (GO:0006677)3.19048254
169actin filament depolymerization (GO:0030042)3.17879304
170neurotransmitter biosynthetic process (GO:0042136)3.17223723
171tricarboxylic acid cycle (GO:0006099)3.17127071
172glycerol metabolic process (GO:0006071)3.17068275
173vitamin biosynthetic process (GO:0009110)3.17036052
174transcytosis (GO:0045056)3.16716737
175biotin metabolic process (GO:0006768)3.16370768
176positive regulation of glycoprotein metabolic process (GO:1903020)3.16227229
177renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.14013427
178antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.13563950
179sphingomyelin metabolic process (GO:0006684)3.10789138
180sphingolipid catabolic process (GO:0030149)3.09278603
181midgut development (GO:0007494)3.08596314
182cobalamin metabolic process (GO:0009235)3.08487414
183positive regulation of respiratory burst (GO:0060267)3.07286719
184high-density lipoprotein particle remodeling (GO:0034375)3.05372774
185plasma lipoprotein particle organization (GO:0071827)3.01911248
186antigen processing and presentation of endogenous antigen (GO:0019883)3.01245513
187angiotensin maturation (GO:0002003)11.1197981
188drug transmembrane transport (GO:0006855)10.1766070
189urate metabolic process (GO:0046415)10.1416278

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.57069663
2RXR_22158963_ChIP-Seq_LIVER_Mouse4.74525774
3PPARA_22158963_ChIP-Seq_LIVER_Mouse4.14132834
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.87803158
5LXR_22158963_ChIP-Seq_LIVER_Mouse3.62699427
6ESR1_21235772_ChIP-Seq_MCF-7_Human3.50001466
7HNF4A_19761587_ChIP-ChIP_CACO-2_Human3.03552087
8BP1_19119308_ChIP-ChIP_Hs578T_Human2.97100759
9CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.66468669
10* CDX2_20551321_ChIP-Seq_CACO-2_Human2.62146038
11TRIM28_21343339_ChIP-Seq_HEK293_Human2.60218690
12CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.59288621
13IRF8_22096565_ChIP-ChIP_GC-B_Human2.53763184
14AR_21909140_ChIP-Seq_LNCAP_Human2.45499633
15GATA1_22025678_ChIP-Seq_K562_Human2.37795104
16TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.36451333
17ESR2_21235772_ChIP-Seq_MCF-7_Human2.33612189
18RARG_19884340_ChIP-ChIP_MEFs_Mouse2.25072919
19SOX2_27498859_Chip-Seq_STOMACH_Mouse2.24855004
20TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.22175682
21ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.18756909
22VDR_22108803_ChIP-Seq_LS180_Human2.17019197
23* GATA4_25053715_ChIP-Seq_YYC3_Human1.94792052
24MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.93498225
25NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.92789967
26TP63_17297297_ChIP-ChIP_HaCaT_Human1.92506352
27CLOCK_20551151_ChIP-Seq_293T_Human1.90528189
28STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.81586202
29NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.78935910
30CDX2_19796622_ChIP-Seq_MESCs_Mouse1.76035829
31GATA6_25053715_ChIP-Seq_YYC3_Human1.72469251
32PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.71674734
33TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.71274415
34EGR1_23403033_ChIP-Seq_LIVER_Mouse1.69780301
35FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.66888744
36* HNF4A_19822575_ChIP-Seq_HepG2_Human1.58711324
37TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.57763473
38ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.57143793
39FOXO3_23340844_ChIP-Seq_DLD1_Human1.56837544
40RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.56284666
41SOX2_20726797_ChIP-Seq_SW620_Human1.55723118
42ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.55406941
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.46383531
44RACK7_27058665_Chip-Seq_MCF-7_Human1.46239584
45TCF4_18268006_ChIP-ChIP_LS174T_Human1.45952113
46THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.44168708
47PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.40323766
48* FOXA2_19822575_ChIP-Seq_HepG2_Human1.39121507
49LXR_22292898_ChIP-Seq_THP-1_Human1.37146843
50EGR1_19032775_ChIP-ChIP_M12_Human1.37052720
51FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.35517973
52IRF8_21731497_ChIP-ChIP_J774_Mouse1.31419000
53PPAR_26484153_Chip-Seq_NCI-H1993_Human1.29108292
54IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.28725050
55FOXA1_25552417_ChIP-Seq_VCAP_Human1.21773405
56EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.16445925
57BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.14560297
58AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.14399123
59STAT3_1855785_ChIP-Seq_MESCs_Mouse1.14287971
60KLF5_25053715_ChIP-Seq_YYC3_Human1.14139723
61VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.13000687
62STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.11587162
63JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.11133838
64RXR_22108803_ChIP-Seq_LS180_Human1.10799828
65SA1_27219007_Chip-Seq_Bcells_Human1.09952661
66SMAD3_21741376_ChIP-Seq_HESCs_Human1.09777990
67GATA1_19941826_ChIP-Seq_K562_Human1.09463139
68CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.08502249
69SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.08364066
70TET1_21451524_ChIP-Seq_MESCs_Mouse1.08246741
71BCOR_27268052_Chip-Seq_Bcells_Human1.07869820
72BCL6_27268052_Chip-Seq_Bcells_Human1.07196882
73CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05650972
74TBX20_22328084_ChIP-Seq_HEART_Mouse1.04197602
75TBX20_22080862_ChIP-Seq_HEART_Mouse1.04197602
76PIAS1_25552417_ChIP-Seq_VCAP_Human1.01728208
77ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.99986412
78TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.99371565
79CDX2_22108803_ChIP-Seq_LS180_Human0.97542048
80PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.95789670
81CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.95457410
82SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.95327689
83CTCF_27219007_Chip-Seq_Bcells_Human0.95268619
84NANOG_20526341_ChIP-Seq_ESCs_Human0.93453189
85KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92974826
86BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.92649576
87SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92518532
88TCF3_18692474_ChIP-Seq_MEFs_Mouse0.92239923
89FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.91430376
90SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.90774260
91SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.89515428
92ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.88977509
93CEBPB_22108803_ChIP-Seq_LS180_Human0.88774997
94GATA2_19941826_ChIP-Seq_K562_Human0.88530377
95DNAJC2_21179169_ChIP-ChIP_NT2_Human0.88483072
96SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.88165669
97NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.86800360
98* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.86151191
99MYC_19915707_ChIP-ChIP_AK7_Human0.85777751
100PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.85302183
101RUNX1_27514584_Chip-Seq_MCF-7_Human0.85237599
102ZNF263_19887448_ChIP-Seq_K562_Human0.85137248
103VDR_24763502_ChIP-Seq_THP-1_Human0.85013886
104CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.84816484
105SALL4_18804426_ChIP-ChIP_XEN_Mouse0.84513659
106NANOG_18692474_ChIP-Seq_MEFs_Mouse0.84250817
107FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.83077697
108PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.81971357
109RAD21_21589869_ChIP-Seq_MESCs_Mouse0.81603825
110SMAD4_21741376_ChIP-Seq_HESCs_Human0.81293068
111Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.80126391
112KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.79958663
113GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.79828722
114CREB1_26743006_Chip-Seq_LNCaP_Human0.79179028
115GATA1_22383799_ChIP-Seq_G1ME_Mouse0.79058475
116TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.78930096
117ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.78828286
118VDR_24787735_ChIP-Seq_THP-1_Human0.78757736
119STAT1_20625510_ChIP-Seq_HELA_Human0.77921212
120P63_26484246_Chip-Seq_KERATINOCYTES_Human0.77334363
121P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.77329561
122FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.76515995
123GATA3_24758297_ChIP-Seq_MCF-7_Human0.75943490
124NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.75351800
125TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.75088309
126EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.74948919
127ESR1_20079471_ChIP-ChIP_T-47D_Human0.74471362
128* TP63_23658742_ChIP-Seq_EP156T_Human0.73650276
129ATF3_27146783_Chip-Seq_COLON_Human0.73241251
130EP300_21415370_ChIP-Seq_HL-1_Mouse0.72893355
131CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.72818580
132SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.72679432
133ERG_21242973_ChIP-ChIP_JURKAT_Human0.71241366
134NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.71115171
135NRF2_20460467_ChIP-Seq_MEFs_Mouse0.71115171
136SMC4_20622854_ChIP-Seq_HELA_Human0.70626923
137P300_27058665_Chip-Seq_ZR-75-30cells_Human0.69893072
138* GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.69100614

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis8.53477678
2MP0004043_abnormal_pH_regulation6.21379587
3MP0004019_abnormal_vitamin_homeostasis4.71120408
4MP0002139_abnormal_hepatobiliary_system4.40699636
5* MP0005332_abnormal_amino_acid4.38318538
6MP0003183_abnormal_peptide_metabolism4.33715781
7MP0009643_abnormal_urine_homeostasis3.86875274
8MP0003195_calcinosis3.85100152
9MP0009379_abnormal_foot_pigmentation3.73990100
10MP0001765_abnormal_ion_homeostasis3.67579045
11MP0002138_abnormal_hepatobiliary_system3.63066640
12MP0009840_abnormal_foam_cell3.60582995
13MP0005377_hearing/vestibular/ear_phenot3.28485719
14MP0003878_abnormal_ear_physiology3.28485719
15MP0001756_abnormal_urination3.03920968
16MP0005636_abnormal_mineral_homeostasis3.00766198
17MP0008875_abnormal_xenobiotic_pharmacok2.98594397
18MP0002136_abnormal_kidney_physiology2.82268965
19MP0005365_abnormal_bile_salt2.59963266
20MP0005085_abnormal_gallbladder_physiolo2.58868382
21MP0003252_abnormal_bile_duct2.57132898
22* MP0010155_abnormal_intestine_physiology2.47298765
23MP0001958_emphysema2.29289775
24MP0005409_darkened_coat_color2.25751508
25MP0001666_abnormal_nutrient_absorption1.83012528
26MP0000490_abnormal_crypts_of1.81637206
27MP0010234_abnormal_vibrissa_follicle1.81156444
28MP0005058_abnormal_lysosome_morphology1.79468652
29MP0010352_gastrointestinal_tract_polyps1.79443973
30MP0002876_abnormal_thyroid_physiology1.78536268
31MP0008961_abnormal_basal_metabolism1.69000979
32MP0003300_gastrointestinal_ulcer1.62606021
33MP0004264_abnormal_extraembryonic_tissu1.61108504
34MP0005584_abnormal_enzyme/coenzyme_acti1.51314146
35MP0004885_abnormal_endolymph1.48938007
36MP0005084_abnormal_gallbladder_morpholo1.48591957
37MP0001188_hyperpigmentation1.45361771
38MP0003186_abnormal_redox_activity1.40873904
39MP0003806_abnormal_nucleotide_metabolis1.32898699
40MP0004147_increased_porphyrin_level1.32598541
41MP0003283_abnormal_digestive_organ1.31967809
42MP0005319_abnormal_enzyme/_coenzyme1.31782342
43MP0005451_abnormal_body_composition1.28377026
44MP0003191_abnormal_cellular_cholesterol1.22425191
45MP0004270_analgesia1.16706689
46MP0000230_abnormal_systemic_arterial1.16427558
47MP0000462_abnormal_digestive_system1.15114379
48MP0004782_abnormal_surfactant_physiolog1.12920584
49MP0003718_maternal_effect1.10902367
50MP0002928_abnormal_bile_duct1.08551562
51MP0002822_catalepsy1.08251463
52MP0002168_other_aberrant_phenotype1.05800594
53MP0006036_abnormal_mitochondrial_physio1.05770048
54MP0001501_abnormal_sleep_pattern1.04973279
55MP0005448_abnormal_energy_balance1.00667305
56MP0002089_abnormal_postnatal_growth/wei0.96785512
57* MP0000538_abnormal_urinary_bladder0.96336715
58MP0001764_abnormal_homeostasis0.96250760
59MP0002971_abnormal_brown_adipose0.95945873
60* MP0002135_abnormal_kidney_morphology0.94603250
61MP0002118_abnormal_lipid_homeostasis0.92108740
62MP0002896_abnormal_bone_mineralization0.91430008
63MP0005666_abnormal_adipose_tissue0.87050572
64MP0010329_abnormal_lipoprotein_level0.86817469
65MP0002796_impaired_skin_barrier0.85725910
66MP0003638_abnormal_response/metabolism_0.83024251
67MP0009115_abnormal_fat_cell0.82300109
68* MP0001845_abnormal_inflammatory_respons0.80018836
69MP0000537_abnormal_urethra_morphology0.79260793
70MP0005670_abnormal_white_adipose0.79012801
71MP0009785_altered_susceptibility_to0.78600457
72MP0001663_abnormal_digestive_system0.77130587
73MP0000465_gastrointestinal_hemorrhage0.72813061
74MP0003724_increased_susceptibility_to0.72390343
75* MP0009642_abnormal_blood_homeostasis0.71565225
76MP0002396_abnormal_hematopoietic_system0.71564600
77MP0002166_altered_tumor_susceptibility0.69923037
78MP0000609_abnormal_liver_physiology0.69317529
79MP0001661_extended_life_span0.68647411
80MP0003866_abnormal_defecation0.67882589
81MP0000604_amyloidosis0.67081778
82MP0005167_abnormal_blood-brain_barrier0.66543518
83MP0003959_abnormal_lean_body0.66472668
84* MP0005535_abnormal_body_temperature0.62767298
85MP0005381_digestive/alimentary_phenotyp0.62495831
86MP0001835_abnormal_antigen_presentation0.62375028
87MP0005025_abnormal_response_to0.62213894
88MP0006082_CNS_inflammation0.61826504
89MP0003303_peritoneal_inflammation0.61798911
90MP0000249_abnormal_blood_vessel0.61468900
91MP0001664_abnormal_digestion0.60044403
92MP0003646_muscle_fatigue0.59766298
93MP0003436_decreased_susceptibility_to0.59714600
94MP0005501_abnormal_skin_physiology0.59274266
95MP0003879_abnormal_hair_cell0.58662685
96MP0009764_decreased_sensitivity_to0.58273339
97MP0005395_other_phenotype0.56565433
98MP0005220_abnormal_exocrine_pancreas0.56512515
99MP0003315_abnormal_perineum_morphology0.56333592
100MP0009333_abnormal_splenocyte_physiolog0.55686503
101MP0004947_skin_inflammation0.54913623
102MP0003172_abnormal_lysosome_physiology0.54169097
103MP0001485_abnormal_pinna_reflex0.52861614
104MP0005174_abnormal_tail_pigmentation0.52803420
105MP0003705_abnormal_hypodermis_morpholog0.52704449
106MP0005334_abnormal_fat_pad0.51684377
107MP0001881_abnormal_mammary_gland0.50442772
108MP0005387_immune_system_phenotype0.50390900
109MP0001790_abnormal_immune_system0.50390900
110MP0000566_synostosis0.50059715
111MP0002098_abnormal_vibrissa_morphology0.48827811
112MP0000747_muscle_weakness0.48524870
113MP0000015_abnormal_ear_pigmentation0.47044111
114MP0000598_abnormal_liver_morphology0.46234393
115MP0000678_abnormal_parathyroid_gland0.45638818
116MP0003795_abnormal_bone_structure0.45598692
117MP0006138_congestive_heart_failure0.45569934
118MP0000371_diluted_coat_color0.45084556
119MP0005310_abnormal_salivary_gland0.44674894
120MP0002078_abnormal_glucose_homeostasis0.43393167
121MP0003953_abnormal_hormone_level0.43349522
122MP0010386_abnormal_urinary_bladder0.42881547
123* MP0008469_abnormal_protein_level0.42556839
124MP0003329_amyloid_beta_deposits0.42023489
125MP0002115_abnormal_skeleton_extremities0.41604184
126MP0005408_hypopigmentation0.40579332
127MP0004742_abnormal_vestibular_system0.40000357
128MP0005165_increased_susceptibility_to0.39374090
129MP0004484_altered_response_of0.39331081
130MP0002069_abnormal_eating/drinking_beha0.39212920
131MP0000477_abnormal_intestine_morphology0.38255785
132MP0005375_adipose_tissue_phenotype0.38075132
133MP0001873_stomach_inflammation0.36767738
134MP0003868_abnormal_feces_composition0.35779762
135MP0006035_abnormal_mitochondrial_morpho0.35680810
136MP0002998_abnormal_bone_remodeling0.34531336
137MP0005166_decreased_susceptibility_to0.32920410
138MP0004858_abnormal_nervous_system0.32122906
139MP0000163_abnormal_cartilage_morphology0.29782366
140MP0008872_abnormal_physiological_respon0.29730886
141MP0001963_abnormal_hearing_physiology0.29651759

Predicted human phenotypes

RankGene SetZ-score
1Increased circulating renin level (HP:0000848)7.64662990
2Metabolic alkalosis (HP:0200114)7.63194805
3Hyperactive renin-angiotensin system (HP:0000841)7.22715735
4Hypokalemic alkalosis (HP:0001949)7.07003653
5Hypomagnesemia (HP:0002917)7.04762399
6Gout (HP:0001997)6.64083174
7Abnormality of chloride homeostasis (HP:0011422)6.49485095
8Polyuria (HP:0000103)6.31043998
9Abnormality of magnesium homeostasis (HP:0004921)6.06844389
10Abnormal urine output (HP:0012590)6.01060250
11Hypobetalipoproteinemia (HP:0003563)5.71586206
12Abnormality of renal excretion (HP:0011036)5.71356641
13Chronic diarrhea (HP:0002028)5.39335482
14Proximal tubulopathy (HP:0000114)5.22792844
15Abnormality of glutamine family amino acid metabolism (HP:0010902)5.14182551
16Tetany (HP:0001281)5.08421251
17Polydipsia (HP:0001959)5.08031891
18Abnormal drinking behavior (HP:0030082)5.08031891
19Hyperuricemia (HP:0002149)5.00023960
20Increased purine levels (HP:0004368)5.00023960
21Abnormality of renin-angiotensin system (HP:0000847)4.94048183
22Hyperaldosteronism (HP:0000859)4.83417343
23Hyperglycinuria (HP:0003108)4.80662071
24Alkalosis (HP:0001948)4.76628355
25Fat malabsorption (HP:0002630)4.73273734
26Renal salt wasting (HP:0000127)4.66821383
27Acanthocytosis (HP:0001927)4.54404888
28Abnormality of purine metabolism (HP:0004352)4.41049280
29Abnormality of vitamin metabolism (HP:0100508)4.02602224
30Systemic lupus erythematosus (HP:0002725)4.00310888
31Hypercalciuria (HP:0002150)3.95858536
32Abnormality of glycine metabolism (HP:0010895)3.91136532
33Abnormality of serine family amino acid metabolism (HP:0010894)3.91136532
34Pigmentary retinal degeneration (HP:0001146)3.82929765
35Ketoacidosis (HP:0001993)3.78504047
36Hypokalemia (HP:0002900)3.75734850
37Generalized aminoaciduria (HP:0002909)3.68879996
38Renal tubular acidosis (HP:0001947)3.48441129
39Abnormality of urine glucose concentration (HP:0011016)3.45875004
40Glycosuria (HP:0003076)3.45875004
41Wide cranial sutures (HP:0010537)3.44581002
42Abdominal distention (HP:0003270)3.27506241
43Abnormality of proline metabolism (HP:0010907)3.26079379
44Hydroxyprolinuria (HP:0003080)3.26079379
45Abnormality of nucleobase metabolism (HP:0010932)3.20446809
46Xanthomatosis (HP:0000991)3.20023196
47Ketosis (HP:0001946)3.16878003
48Abnormality of monocarboxylic acid metabolism (HP:0010996)3.13920787
49Abnormality of potassium homeostasis (HP:0011042)3.13620528
50Congenital sensorineural hearing impairment (HP:0008527)3.10338614
51Hyperphosphaturia (HP:0003109)3.09829048
52Abnormality of aspartate family amino acid metabolism (HP:0010899)2.98961402
53Steatorrhea (HP:0002570)2.97477452
54Megaloblastic anemia (HP:0001889)2.95892105
55Abnormality of fatty-acid metabolism (HP:0004359)2.95046170
56Delayed epiphyseal ossification (HP:0002663)2.92700052
57Abnormal urine phosphate concentration (HP:0012599)2.90215463
58Nephrolithiasis (HP:0000787)2.87369153
59Posterior subcapsular cataract (HP:0007787)2.86776343
60Hypolipoproteinemia (HP:0010981)2.85873501
61Nephrocalcinosis (HP:0000121)2.83520382
62Hyperparathyroidism (HP:0000843)2.73119974
63Dehydration (HP:0001944)2.67610149
64Delayed CNS myelination (HP:0002188)2.65014623
65Abnormality of small intestinal villus morphology (HP:0011472)2.64587279
66Villous atrophy (HP:0011473)2.64587279
67Eczematoid dermatitis (HP:0000976)2.59998361
68Hemorrhage of the eye (HP:0011885)2.59834737
69Vacuolated lymphocytes (HP:0001922)2.56810433
70Malnutrition (HP:0004395)2.55962994
71Hyperglycinemia (HP:0002154)2.55725038
72Hypophosphatemia (HP:0002148)2.55114428
73Vascular calcification (HP:0004934)2.54189875
74Widely patent fontanelles and sutures (HP:0004492)2.50920441
75Enlarged epiphyses (HP:0010580)2.47837371
76Focal segmental glomerulosclerosis (HP:0000097)2.44589605
77Abnormality of sodium homeostasis (HP:0010931)2.40240571
78Abnormality of dicarboxylic acid metabolism (HP:0010995)2.39023891
79Dicarboxylic aciduria (HP:0003215)2.39023891
80Hyponatremia (HP:0002902)2.37751083
81Rickets (HP:0002748)2.37252903
82Hyperammonemia (HP:0001987)2.36646200
83Abnormality of sulfur amino acid metabolism (HP:0004339)2.33343372
84Metabolic acidosis (HP:0001942)2.31353733
85Metaphyseal cupping (HP:0003021)2.30075393
86Right ventricular cardiomyopathy (HP:0011663)2.29981263
87Adrenal overactivity (HP:0002717)2.29098981
88Confusion (HP:0001289)2.28951097
89Cardiovascular calcification (HP:0011915)2.26129265
90Vomiting (HP:0002013)2.24650643
91Flat acetabular roof (HP:0003180)2.23609898
92Abnormal glucose tolerance (HP:0001952)2.18617811
93Epidermoid cyst (HP:0200040)2.18196401
94Subcapsular cataract (HP:0000523)2.16702896
95Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.15052716
96Hyperphosphatemia (HP:0002905)2.13599941
97Protuberant abdomen (HP:0001538)2.13188396
98Abnormal tarsal ossification (HP:0008369)2.11915019
99Facial shape deformation (HP:0011334)2.10497897
100Potter facies (HP:0002009)2.10497897
101Thin bony cortex (HP:0002753)2.10343872
102Renal tubular dysfunction (HP:0000124)2.08790660
103Enlarged kidneys (HP:0000105)2.08180472
104Abnormality of renal resorption (HP:0011038)2.03826369
105Cerebral palsy (HP:0100021)2.03784558
106Pancreatitis (HP:0001733)2.03719701
107Glomerulonephritis (HP:0000099)2.03105069
108Gingivitis (HP:0000230)2.00540123
109Abnormal enzyme/coenzyme activity (HP:0012379)2.00047312
110Gastrointestinal dysmotility (HP:0002579)1.99437825
111Tubular atrophy (HP:0000092)1.99117499
112Chondrocalcinosis (HP:0000934)1.97309081
113Lethargy (HP:0001254)1.96998501
114Poikilocytosis (HP:0004447)1.94824944
115Abnormality of alkaline phosphatase activity (HP:0004379)1.94423740
116Decreased circulating renin level (HP:0003351)1.94271266
117Methylmalonic aciduria (HP:0012120)1.91669553
118Intrahepatic cholestasis (HP:0001406)1.91243470
119Abnormality of aromatic amino acid family metabolism (HP:0004338)1.90151100
120Abnormality of complement system (HP:0005339)1.87680449
121Tubulointerstitial fibrosis (HP:0005576)1.87298581
122Bilateral sensorineural hearing impairment (HP:0008619)1.87082231
123Growth hormone excess (HP:0000845)1.85486045
124Abnormality of pyrimidine metabolism (HP:0004353)1.84082663
125Abnormality of Sharpey fibers (HP:0100685)1.84052264
126Multiple lipomas (HP:0001012)1.83500471
127Complement deficiency (HP:0004431)1.81450616
128Nephritis (HP:0000123)1.80227939
129Conjugated hyperbilirubinemia (HP:0002908)1.79670025
130Bicornuate uterus (HP:0000813)1.77752723
131Hypotension (HP:0002615)1.77204392
132Nausea (HP:0002018)1.76885964
133Abnormality of carpal bone ossification (HP:0006257)1.76151429
134Symptomatic seizures (HP:0011145)1.74904959
135Metaphyseal irregularity (HP:0003025)1.74681260
136Abnormality of the vitamin B12 metabolism (HP:0004341)1.74557173
137Segmental peripheral demyelination/remyelination (HP:0003481)1.74156441
138Abnormality of the costochondral junction (HP:0000919)1.73340647
139Pili torti (HP:0003777)1.72748100
140Abnormal biliary tract morphology (HP:0012440)1.71430824
141Glomerulosclerosis (HP:0000096)1.68252567
142Irritability (HP:0000737)1.67208999
143Sensorimotor neuropathy (HP:0007141)1.63135100
144Abnormality of vitamin B metabolism (HP:0004340)1.60824309
145Late onset (HP:0003584)1.59228536
146Ileus (HP:0002595)1.59050369
147Lymphangioma (HP:0100764)1.58834753
148Tachypnea (HP:0002789)1.58055465
149Generalized muscle weakness (HP:0003324)1.54615063

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK38.71642973
2WNK48.31305240
3ACVR1B8.13615683
4OXSR17.40832406
5STK393.90736026
6EPHA23.17622668
7BCKDK2.53483004
8STK38L2.27414585
9TESK22.18464204
10MST41.98613730
11PDK31.91018297
12PDK41.91018297
13NEK11.83615371
14WNK11.79786194
15MST1R1.75825439
16SGK2231.67030821
17SGK4941.67030821
18TYK21.63613909
19EPHA31.57698378
20PDK21.49428985
21MAP3K121.45493779
22TNIK1.39279993
23MAP4K11.29652405
24FRK1.27764152
25RIPK41.27725981
26PRPF4B1.20398522
27GRK61.16757203
28AKT31.13434693
29STK241.09991273
30MAP3K11.08941090
31STK381.08712784
32FGFR31.08707855
33EPHA41.08593240
34LRRK21.03007687
35SGK30.97185375
36SGK20.90767414
37FGFR40.90394978
38CDC42BPA0.88119280
39EPHB10.87840443
40NLK0.86242104
41PTK60.79691939
42RIPK10.79330190
43MAP3K70.73102714
44PTK20.72896836
45GSK3A0.68168900
46PRKCI0.68058540
47LMTK20.66627692
48MYLK0.64850699
49PINK10.62461003
50PRKAA10.58574949
51MET0.58096152
52PAK40.58085834
53DYRK1B0.56191275
54MAP3K30.55934320
55IRAK10.55148706
56MAP2K20.54213623
57ERN10.53429471
58SGK10.52748005
59CASK0.52507934
60JAK10.52183865
61BMPR20.51619452
62MAPK110.51417590
63PDPK10.50734106
64MAP3K20.49404213
65STK100.49075059
66PRKAA20.49028577
67TBK10.48995756
68RET0.47218286
69FER0.47188114
70CAMK2D0.45520821
71NME10.45191983
72MAP3K140.42462648
73TIE10.42300878
74FYN0.42179665
75YES10.42147229
76PRKG20.41534021
77CSF1R0.39555037
78PAK30.38867496
79ABL20.37878399
80EPHB20.35576528
81IKBKE0.33695951
82PDK10.33468973
83TGFBR20.32594057
84INSRR0.32322071
85STK110.32172773
86ZAP700.32038979
87NEK60.31030453
88CAMK2G0.29224090
89CDK190.29167294
90CDK60.29082586
91SMG10.28480127
92BTK0.27981489
93PRKCZ0.27687187
94GRK10.26541430
95SYK0.25989268
96PRKCD0.25879096
97CAMK2B0.25219354
98MELK0.24530920
99LATS10.24059720
100PRKD20.23555533
101PTK2B0.22553321
102PIK3CG0.22293951
103MAPKAPK20.22088554
104NTRK10.21926468
105LYN0.21247268
106JAK30.21118934
107TAOK10.21008079
108PRKACG0.20824738
109TEC0.20369130
110TRIB30.20099104
111MAP3K110.18673017
112LCK0.18544211
113RPS6KA20.18334402
114BMX0.17992255
115DAPK20.17909124
116TESK10.17742051
117PRKCA0.17303333
118DDR20.17121202
119SCYL20.16917798
120JAK20.16494788
121AKT20.14812534
122PIM10.13303088
123MATK0.13004488
124ERBB40.12690390
125KSR20.12244194
126ITK0.11582620
127MAP2K10.10668128
128ERBB20.10447806
129ROCK10.08924319
130SRC0.07897134
131PRKACA0.07592763
132TTK0.06434672
133MAPK150.06344428
134PIK3CA0.06275499
135PDGFRA0.05227493
136CSK0.04963069
137MAP2K30.04956954
138PRKCQ0.03915518
139MAP3K80.03243899
140PRKCH0.03165696
141INSR0.02967506
142CSNK1A10.02550586
143MAP2K60.02095583
144IRAK30.01843721
145MINK10.00851148
146MAP3K100.00566429
147IGF1R0.00565431

Predicted pathways (KEGG)

RankGene SetZ-score
1Butanoate metabolism_Homo sapiens_hsa006503.62852006
2Cyanoamino acid metabolism_Homo sapiens_hsa004603.60924436
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.45815059
4Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049643.40948326
5Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.12368634
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.07032180
7Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006303.05685993
8Propanoate metabolism_Homo sapiens_hsa006402.97886476
92-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.95038868
10Pentose and glucuronate interconversions_Homo sapiens_hsa000402.73921111
11Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.41093357
12Vitamin digestion and absorption_Homo sapiens_hsa049772.35545020
13Peroxisome_Homo sapiens_hsa041462.35342098
14Caffeine metabolism_Homo sapiens_hsa002322.33778717
15Tryptophan metabolism_Homo sapiens_hsa003802.33217587
16Fatty acid degradation_Homo sapiens_hsa000712.31012301
17Sulfur metabolism_Homo sapiens_hsa009202.27292293
18Pyruvate metabolism_Homo sapiens_hsa006202.27152642
19Bile secretion_Homo sapiens_hsa049762.04177699
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.91101835
21Collecting duct acid secretion_Homo sapiens_hsa049661.87972490
22beta-Alanine metabolism_Homo sapiens_hsa004101.85809284
23Linoleic acid metabolism_Homo sapiens_hsa005911.84108227
24Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.78653812
25Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.76807177
26Mineral absorption_Homo sapiens_hsa049781.73713044
27Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.65644688
28Fatty acid metabolism_Homo sapiens_hsa012121.64694994
29Carbon metabolism_Homo sapiens_hsa012001.62247423
30Glutathione metabolism_Homo sapiens_hsa004801.61874199
31Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.47320553
32Arginine and proline metabolism_Homo sapiens_hsa003301.43369005
33Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.41096378
34PPAR signaling pathway_Homo sapiens_hsa033201.38393264
35Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.37344496
36Arginine biosynthesis_Homo sapiens_hsa002201.32386254
37Other glycan degradation_Homo sapiens_hsa005111.27551999
38Lysine degradation_Homo sapiens_hsa003101.26439956
39* Protein digestion and absorption_Homo sapiens_hsa049741.25860860
40Histidine metabolism_Homo sapiens_hsa003401.21733168
41Starch and sucrose metabolism_Homo sapiens_hsa005001.20038281
42Renin-angiotensin system_Homo sapiens_hsa046141.19907416
43Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.18058111
44Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.15628445
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.12289240
46Asthma_Homo sapiens_hsa053101.06767165
47Fructose and mannose metabolism_Homo sapiens_hsa000511.02616498
48Nitrogen metabolism_Homo sapiens_hsa009101.01744680
49Selenocompound metabolism_Homo sapiens_hsa004501.01341099
50Glycerolipid metabolism_Homo sapiens_hsa005611.00085980
51Biosynthesis of amino acids_Homo sapiens_hsa012300.99130321
52Intestinal immune network for IgA production_Homo sapiens_hsa046720.96853489
53Ether lipid metabolism_Homo sapiens_hsa005650.94417520
54Primary bile acid biosynthesis_Homo sapiens_hsa001200.93341052
55Folate biosynthesis_Homo sapiens_hsa007900.87987561
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.86296917
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.82860315
58Phenylalanine metabolism_Homo sapiens_hsa003600.82345308
59Allograft rejection_Homo sapiens_hsa053300.79868733
60Carbohydrate digestion and absorption_Homo sapiens_hsa049730.78117775
61Maturity onset diabetes of the young_Homo sapiens_hsa049500.74390918
62Autoimmune thyroid disease_Homo sapiens_hsa053200.73922639
63Graft-versus-host disease_Homo sapiens_hsa053320.70257949
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.67640215
65Staphylococcus aureus infection_Homo sapiens_hsa051500.65516385
66Oxidative phosphorylation_Homo sapiens_hsa001900.64732732
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.63232011
68Thyroid hormone synthesis_Homo sapiens_hsa049180.61290407
69Pentose phosphate pathway_Homo sapiens_hsa000300.61109425
70Glycerophospholipid metabolism_Homo sapiens_hsa005640.60349054
71Fatty acid elongation_Homo sapiens_hsa000620.57894994
72Metabolic pathways_Homo sapiens_hsa011000.53592608
73Lysosome_Homo sapiens_hsa041420.53563251
74Type I diabetes mellitus_Homo sapiens_hsa049400.52094252
75Chemical carcinogenesis_Homo sapiens_hsa052040.52033289
76Gastric acid secretion_Homo sapiens_hsa049710.50699170
77Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.46848545
78Drug metabolism - other enzymes_Homo sapiens_hsa009830.46198287
79Glycosaminoglycan degradation_Homo sapiens_hsa005310.44015148
80Renin secretion_Homo sapiens_hsa049240.41104385
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39514829
82Fatty acid biosynthesis_Homo sapiens_hsa000610.39088869
83Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.36185723
84Fat digestion and absorption_Homo sapiens_hsa049750.33845979
85Vibrio cholerae infection_Homo sapiens_hsa051100.33561455
86Parkinsons disease_Homo sapiens_hsa050120.33460798
87Antigen processing and presentation_Homo sapiens_hsa046120.33449676
88Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.33434227
89Retinol metabolism_Homo sapiens_hsa008300.33198196
90ABC transporters_Homo sapiens_hsa020100.33054872
91Arachidonic acid metabolism_Homo sapiens_hsa005900.31841881
92Galactose metabolism_Homo sapiens_hsa000520.31531136
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30812641
94Leishmaniasis_Homo sapiens_hsa051400.27041293
95Sphingolipid metabolism_Homo sapiens_hsa006000.26913156
96Choline metabolism in cancer_Homo sapiens_hsa052310.23048984
97Tyrosine metabolism_Homo sapiens_hsa003500.23011734
98Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.20975123
99Sulfur relay system_Homo sapiens_hsa041220.20834141
100Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.20830694
101Steroid biosynthesis_Homo sapiens_hsa001000.20557016
102Cocaine addiction_Homo sapiens_hsa050300.20294732
103Glucagon signaling pathway_Homo sapiens_hsa049220.18534603
104Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.14512217
105Pertussis_Homo sapiens_hsa051330.13431171
106Viral myocarditis_Homo sapiens_hsa054160.12287090
107Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.11363503
108Insulin secretion_Homo sapiens_hsa049110.10103005
109Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.09857303
110Synaptic vesicle cycle_Homo sapiens_hsa047210.09556641
111Inositol phosphate metabolism_Homo sapiens_hsa005620.09386878
112Cardiac muscle contraction_Homo sapiens_hsa042600.09100923
113Alzheimers disease_Homo sapiens_hsa050100.09035731
114Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.08669667
115Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.08230411
116Toxoplasmosis_Homo sapiens_hsa051450.07561089
117Insulin resistance_Homo sapiens_hsa049310.07267087
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.07036371
119African trypanosomiasis_Homo sapiens_hsa051430.06980623
120Hematopoietic cell lineage_Homo sapiens_hsa046400.06901892
121Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.06119856
122GnRH signaling pathway_Homo sapiens_hsa049120.05918539
123Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.05316453
124Amphetamine addiction_Homo sapiens_hsa050310.04472632
125Tight junction_Homo sapiens_hsa045300.04231113
126Adipocytokine signaling pathway_Homo sapiens_hsa049200.03332914
127Leukocyte transendothelial migration_Homo sapiens_hsa046700.03264365
128Bladder cancer_Homo sapiens_hsa052190.02962233
129Hepatitis C_Homo sapiens_hsa051600.02636539
130Pancreatic secretion_Homo sapiens_hsa049720.00569403

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