MEPCE

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of histone deacetylation (GO:0031065)4.66808074
2regulation of gamma-delta T cell differentiation (GO:0045586)4.29275896
3regulation of mammary gland epithelial cell proliferation (GO:0033599)4.27855704
4heterochromatin organization (GO:0070828)4.08086370
5negative regulation of homotypic cell-cell adhesion (GO:0034111)3.97612367
6negative regulation of erythrocyte differentiation (GO:0045647)3.86523028
7positive thymic T cell selection (GO:0045059)3.81137371
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.76387511
9antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.76387511
10negative regulation of histone methylation (GO:0031061)3.72829526
11regulation of RNA export from nucleus (GO:0046831)3.69284561
12adherens junction assembly (GO:0034333)3.63057520
13regulation of gamma-delta T cell activation (GO:0046643)3.56495874
14positive regulation of Cdc42 GTPase activity (GO:0043089)3.56377407
15mRNA stabilization (GO:0048255)3.54465406
16RNA stabilization (GO:0043489)3.54465406
17regulation of early endosome to late endosome transport (GO:2000641)3.53742686
18intracellular estrogen receptor signaling pathway (GO:0030520)3.53378947
19pre-miRNA processing (GO:0031054)3.52712397
20negative regulation of cell killing (GO:0031342)3.50976404
21negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.50976404
22positive regulation of gamma-delta T cell activation (GO:0046645)3.48400607
23positive regulation of protein deacetylation (GO:0090312)3.45466790
24peptidyl-lysine dimethylation (GO:0018027)3.42266762
25cell-substrate adherens junction assembly (GO:0007045)3.36893503
26focal adhesion assembly (GO:0048041)3.36893503
27thymic T cell selection (GO:0045061)3.31891414
28morphogenesis of an endothelium (GO:0003159)3.23856575
29endothelial tube morphogenesis (GO:0061154)3.23856575
30antigen processing and presentation of endogenous antigen (GO:0019883)3.23296947
31regulation of histone H3-K9 methylation (GO:0051570)3.23267871
32activation of Rac GTPase activity (GO:0032863)3.22376218
33regulation of apoptotic process involved in morphogenesis (GO:1902337)3.21419398
34folic acid-containing compound biosynthetic process (GO:0009396)3.15269299
35maternal placenta development (GO:0001893)3.13668443
36mitotic chromosome condensation (GO:0007076)3.13110202
37histone H2A monoubiquitination (GO:0035518)3.12185277
38modulation by virus of host process (GO:0019054)3.11667247
39spliceosomal tri-snRNP complex assembly (GO:0000244)3.09851467
40proline biosynthetic process (GO:0006561)3.08455723
41protein localization to endosome (GO:0036010)3.07505096
42negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.05487088
43modulation by symbiont of host cellular process (GO:0044068)3.04959069
44chromatin assembly (GO:0031497)3.04155545
45regulation of nucleobase-containing compound transport (GO:0032239)3.03119841
46viral transcription (GO:0019083)3.00776340
47positive regulation of gene expression, epigenetic (GO:0045815)3.00220913
48regulation of translational fidelity (GO:0006450)2.98986377
49trophectodermal cell differentiation (GO:0001829)2.98370679
503-UTR-mediated mRNA stabilization (GO:0070935)2.96661599
51activation of MAPKKK activity (GO:0000185)2.92266079
52gene silencing (GO:0016458)2.90662931
53chromatin silencing (GO:0006342)2.88391772
54negative regulation of cell size (GO:0045792)2.87454649
55positive T cell selection (GO:0043368)2.86573884
56negative regulation of viral release from host cell (GO:1902187)2.86167938
57translational termination (GO:0006415)2.85315938
58nucleosome disassembly (GO:0006337)2.84591352
59protein-DNA complex disassembly (GO:0032986)2.84591352
60DNA unwinding involved in DNA replication (GO:0006268)2.84272673
61negative regulation of gene expression, epigenetic (GO:0045814)2.83403719
62gene silencing by RNA (GO:0031047)2.81353067
63antigen processing and presentation via MHC class Ib (GO:0002475)2.79707949
64cellular protein complex localization (GO:0034629)2.79610910
65regulation of glucose import in response to insulin stimulus (GO:2001273)2.78595578
66T cell selection (GO:0045058)2.78480722
67endothelial cell chemotaxis (GO:0035767)2.78006426
68synaptonemal complex assembly (GO:0007130)2.77465017
69ncRNA 3-end processing (GO:0043628)2.76846966
70protein localization to chromosome, centromeric region (GO:0071459)2.76299153
71regulation of interleukin-12 biosynthetic process (GO:0045075)2.76155376
72DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.75792884
73megakaryocyte development (GO:0035855)2.74882874
74chromosome condensation (GO:0030261)2.74862546
75protein localization to kinetochore (GO:0034501)2.74440303
76regulation of integrin activation (GO:0033623)2.74282370
77positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.74157387
78regulation of hippo signaling (GO:0035330)2.73606546
79nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.72175807
80regulation of cholesterol homeostasis (GO:2000188)2.72081124
81mannose metabolic process (GO:0006013)2.71309608
82adenosine receptor signaling pathway (GO:0001973)2.70118790
83positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.69118438
84response to peptidoglycan (GO:0032494)2.68410138
85neutrophil activation involved in immune response (GO:0002283)2.68402159
86regulation of mRNA stability (GO:0043488)2.67149408
87mitotic sister chromatid cohesion (GO:0007064)2.66892719
88regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.66676979
89negative T cell selection (GO:0043383)2.64641374
90apoptotic process involved in morphogenesis (GO:0060561)2.64421521
91negative thymic T cell selection (GO:0045060)2.63830181
92glucose catabolic process (GO:0006007)2.62885360
93positive regulation of receptor recycling (GO:0001921)2.62882596
94DNA damage response, signal transduction resulting in transcription (GO:0042772)2.62870536
95negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.62620533
96cellular response to virus (GO:0098586)2.60782325
97nuclear pore complex assembly (GO:0051292)2.60448309
98regulation of RNA stability (GO:0043487)2.60084094
99positive regulation by host of viral transcription (GO:0043923)2.59999110
100cell-substrate junction assembly (GO:0007044)2.59543750
101protein complex localization (GO:0031503)2.59369836
102mitotic G1 DNA damage checkpoint (GO:0031571)2.59022260
103natural killer cell differentiation (GO:0001779)2.58520493
104negative regulation of histone modification (GO:0031057)2.58513797
105ribosomal small subunit assembly (GO:0000028)2.57941924
106corticosteroid receptor signaling pathway (GO:0031958)2.57782969
107pinocytosis (GO:0006907)2.57636548
108translational elongation (GO:0006414)2.57600106
109regulation of translational termination (GO:0006449)2.57154868
110epithelial cell differentiation involved in prostate gland development (GO:0060742)2.54967094
111glucocorticoid receptor signaling pathway (GO:0042921)2.54754764
112pentose-phosphate shunt (GO:0006098)2.54375591
113negative regulation of RNA splicing (GO:0033119)2.54355956
114stress fiber assembly (GO:0043149)2.53562243
115synaptonemal complex organization (GO:0070193)2.53335995
116COPI coating of Golgi vesicle (GO:0048205)2.52575713
117Golgi transport vesicle coating (GO:0048200)2.52575713
118negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.50044587
119regulation of NFAT protein import into nucleus (GO:0051532)2.49338320
120T cell apoptotic process (GO:0070231)2.48098578
121regulation of histone H3-K27 methylation (GO:0061085)2.47937284
122maturation of SSU-rRNA (GO:0030490)2.47786815
123mitotic G1/S transition checkpoint (GO:0044819)2.46738228
124positive regulation of keratinocyte differentiation (GO:0045618)2.44949826
125histone H3-K9 demethylation (GO:0033169)2.44516718
126lymph vessel development (GO:0001945)2.44138938
127embryonic process involved in female pregnancy (GO:0060136)2.43070937
128regulation of histone deacetylation (GO:0031063)2.42910845
129negative regulation of mRNA metabolic process (GO:1903312)2.42598120
130NADPH regeneration (GO:0006740)2.42400947
131nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.41480345
132histone H4-K16 acetylation (GO:0043984)2.40476527
133JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.40378372
134epithelial cell-cell adhesion (GO:0090136)2.40365726
135regulation of type I interferon-mediated signaling pathway (GO:0060338)2.39897770
136ribosomal small subunit biogenesis (GO:0042274)2.39854127
137modulation by virus of host morphology or physiology (GO:0019048)2.39129648
138poly(A)+ mRNA export from nucleus (GO:0016973)2.38098504
139negative regulation of chromatin modification (GO:1903309)2.38055205
140response to laminar fluid shear stress (GO:0034616)2.38008645
141germ cell migration (GO:0008354)2.37775382
142regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.37616592
143regulation of sister chromatid cohesion (GO:0007063)2.36458829
144response to UV-C (GO:0010225)2.36380763
145positive regulation of triglyceride biosynthetic process (GO:0010867)2.36378477
146mitotic sister chromatid segregation (GO:0000070)2.35184702
147cellular response to arsenic-containing substance (GO:0071243)2.34859907
148NIK/NF-kappaB signaling (GO:0038061)2.34160790
149histone H3-K36 demethylation (GO:0070544)2.28750867
150regulation of T-helper 2 cell differentiation (GO:0045628)2.27035085
151positive regulation of protein dephosphorylation (GO:0035307)2.25687271
152urea cycle (GO:0000050)2.23547960
153platelet aggregation (GO:0070527)2.23285473
154negative regulation of adherens junction organization (GO:1903392)2.22877098
155negative regulation of focal adhesion assembly (GO:0051895)2.22877098
156negative regulation of cell junction assembly (GO:1901889)2.22877098
157regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 2.22404828
158negative regulation of stress fiber assembly (GO:0051497)2.20928072
159positive regulation of blood vessel endothelial cell migration (GO:0043536)2.19484175
160response to muramyl dipeptide (GO:0032495)2.19432792
161activation of JUN kinase activity (GO:0007257)2.18684690
162negative regulation of skeletal muscle tissue development (GO:0048642)2.18684632
163UV protection (GO:0009650)2.18601869
164regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.17297812
165positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.17297812
166mitochondrial fusion (GO:0008053)2.16901875
167cellular response to epidermal growth factor stimulus (GO:0071364)2.15676664
168lipopolysaccharide-mediated signaling pathway (GO:0031663)2.13055160
169regulation of leukocyte degranulation (GO:0043300)2.12703930
170modulation by symbiont of host defense response (GO:0052031)2.12138181
171modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.12138181
172modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.12138181
173positive regulation by organism of defense response of other organism involved in symbiotic interact2.12138181
174modulation by symbiont of host immune response (GO:0052553)2.12138181
175positive regulation by symbiont of host defense response (GO:0052509)2.12138181

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_22102868_ChIP-Seq_BL_Human3.97847246
2E2F7_22180533_ChIP-Seq_HELA_Human3.74261825
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.36094997
4VDR_21846776_ChIP-Seq_THP-1_Human2.82815354
5* TCF7_22412390_ChIP-Seq_EML_Mouse2.70725855
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.63619296
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.56243663
8TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.33374158
9KDM2B_26808549_Chip-Seq_DND41_Human2.31332447
10KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.30869075
11KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.30727329
12* MAF_26560356_Chip-Seq_TH1_Human2.06257316
13TP63_17297297_ChIP-ChIP_HaCaT_Human2.03241210
14KDM2B_26808549_Chip-Seq_SUP-B15_Human2.02450601
15UTX_26944678_Chip-Seq_JUKART_Human2.01002966
16SCL_19346495_ChIP-Seq_HPC-7_Human2.00014434
17STAT6_21828071_ChIP-Seq_BEAS2B_Human1.99930145
18EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.99129527
19ELK3_25401928_ChIP-Seq_HUVEC_Human1.96962408
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.84565995
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.80097610
22RARG_19884340_ChIP-ChIP_MEFs_Mouse1.75934069
23STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.73021820
24STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.72225355
25TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.67847442
26* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.67688694
27ZNF263_19887448_ChIP-Seq_K562_Human1.67132110
28CIITA_25753668_ChIP-Seq_RAJI_Human1.66289884
29LXR_22292898_ChIP-Seq_THP-1_Human1.63621584
30STAT3_1855785_ChIP-Seq_MESCs_Mouse1.61094886
31E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.60612107
32MAF_26560356_Chip-Seq_TH2_Human1.57715904
33MYB_26560356_Chip-Seq_TH1_Human1.56571813
34* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.55889010
35KDM2B_26808549_Chip-Seq_JURKAT_Human1.54539277
36* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.52540999
37RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.51228090
38PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.50125424
39VDR_24763502_ChIP-Seq_THP-1_Human1.49299574
40* MYB_26560356_Chip-Seq_TH2_Human1.47860744
41RUNX1_22412390_ChIP-Seq_EML_Mouse1.44200251
42* NCOR1_26117541_ChIP-Seq_K562_Human1.43460994
43SRY_22984422_ChIP-ChIP_TESTIS_Rat1.43358892
44BRD4_27068464_Chip-Seq_AML-cells_Mouse1.42780438
45ESR2_21235772_ChIP-Seq_MCF-7_Human1.42183427
46TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.41612295
47ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.40878659
48PPARA_22158963_ChIP-Seq_LIVER_Mouse1.40853406
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.39759867
50RACK7_27058665_Chip-Seq_MCF-7_Human1.39093659
51MYC_18555785_ChIP-Seq_MESCs_Mouse1.38933025
52* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.36220049
53KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.34393728
54MYC_19079543_ChIP-ChIP_MESCs_Mouse1.30958163
55ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.30645867
56MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.30557200
57ATF3_27146783_Chip-Seq_COLON_Human1.30350294
58MYB_21317192_ChIP-Seq_ERMYB_Mouse1.29754078
59NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.27622428
60ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.27354718
61SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.25963042
62KDM5A_27292631_Chip-Seq_BREAST_Human1.23577312
63KLF4_18555785_ChIP-Seq_MESCs_Mouse1.23354405
64GATA1_22383799_ChIP-Seq_G1ME_Mouse1.21638272
65E2F4_17652178_ChIP-ChIP_JURKAT_Human1.21366584
66HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.20865419
67UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.19016623
68RXR_22158963_ChIP-Seq_LIVER_Mouse1.17860567
69NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.16624847
70SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.16517668
71CREB1_26743006_Chip-Seq_LNCaP_Human1.15575426
72P68_20966046_ChIP-Seq_HELA_Human1.15099628
73SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.13580855
74TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.13345672
75* ELF1_20517297_ChIP-Seq_JURKAT_Human1.13097731
76EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.13080147
77SMC4_20622854_ChIP-Seq_HELA_Human1.12518747
78CTCF_27219007_Chip-Seq_ERYTHROID_Human1.10828028
79P300_27058665_Chip-Seq_ZR-75-30cells_Human1.10372043
80MYC_18358816_ChIP-ChIP_MESCs_Mouse1.10344012
81* CTCF_21964334_ChIP-Seq_BJAB-B_Human1.10029196
82CTCF_21964334_Chip-Seq_Bcells_Human1.09169696
83* NOTCH1_21737748_ChIP-Seq_TLL_Human1.08824440
84ZFX_18555785_ChIP-Seq_MESCs_Mouse1.08538412
85KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.07925428
86ZFP281_27345836_Chip-Seq_ESCs_Mouse1.07630365
87* XRN2_22483619_ChIP-Seq_HELA_Human1.07387483
88SA1_27219007_Chip-Seq_ERYTHROID_Human1.06466458
89KDM2B_26808549_Chip-Seq_K562_Human1.04962466
90CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.04061113
91CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.03600613
92* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.03537368
93BCOR_27268052_Chip-Seq_Bcells_Human1.02918390
94SPI1_23127762_ChIP-Seq_K562_Human1.02694676
95CLOCK_20551151_ChIP-Seq_293T_Human1.02675206
96* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.01764643
97E2F1_21310950_ChIP-Seq_MCF-7_Human1.01183627
98MYC_19030024_ChIP-ChIP_MESCs_Mouse1.00450865
99TFEB_21752829_ChIP-Seq_HELA_Human1.00377155
100PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.99876597
101* GATA1_19941827_ChIP-Seq_MEL_Mouse0.99759136
102* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.99679123
103STAT4_19710469_ChIP-ChIP_TH1__Mouse0.99111108
104* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.98480375
105PU.1_20513432_ChIP-Seq_Bcells_Mouse0.98066785
106RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97999238
107GATA1_19941826_ChIP-Seq_K562_Human0.97753985
108SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.97597623
109THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.97560374
110NANOG_21062744_ChIP-ChIP_HESCs_Human0.97350170
111THAP11_20581084_ChIP-Seq_MESCs_Mouse0.97262540
112TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96701558
113ZFP281_18757296_ChIP-ChIP_E14_Mouse0.96475524
114KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.96348084
115NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.95205013
116TET1_21451524_ChIP-Seq_MESCs_Mouse0.94177492
117EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94043069
118RUNX1_27514584_Chip-Seq_MCF-7_Human0.93845128
119TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92587515
120POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.92445032
121TP53_22127205_ChIP-Seq_IMR90_Human0.90854768
122SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.88995101
123TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.88332804
124GATA3_27048872_Chip-Seq_THYMUS_Human0.87324969
125GATA2_22383799_ChIP-Seq_G1ME_Mouse0.87051169
126AR_21909140_ChIP-Seq_LNCAP_Human0.86801100
127* SPI1_23547873_ChIP-Seq_NB4_Human0.86737434

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009278_abnormal_bone_marrow2.86523513
2MP0005058_abnormal_lysosome_morphology2.73299406
3MP0010352_gastrointestinal_tract_polyps2.70019273
4MP0005451_abnormal_body_composition2.69793454
5MP0003763_abnormal_thymus_physiology2.43915333
6MP0003705_abnormal_hypodermis_morpholog2.42016596
7MP0003693_abnormal_embryo_hatching2.41456527
8MP0008961_abnormal_basal_metabolism2.34165050
9MP0003300_gastrointestinal_ulcer2.22999137
10MP0005397_hematopoietic_system_phenotyp2.21824217
11MP0001545_abnormal_hematopoietic_system2.21824217
12MP0009840_abnormal_foam_cell2.17296765
13MP0004185_abnormal_adipocyte_glucose2.14857398
14MP0008260_abnormal_autophagy2.12253104
15MP0004808_abnormal_hematopoietic_stem2.08941049
16MP0002396_abnormal_hematopoietic_system2.08594077
17MP0003303_peritoneal_inflammation2.00108751
18MP0000685_abnormal_immune_system1.91314844
19MP0004957_abnormal_blastocyst_morpholog1.82069788
20MP0005623_abnormal_meninges_morphology1.80889873
21MP0002653_abnormal_ependyma_morphology1.78433156
22MP0005076_abnormal_cell_differentiation1.77731206
23MP0001849_ear_inflammation1.77572120
24MP0003111_abnormal_nucleus_morphology1.75943429
25MP0001730_embryonic_growth_arrest1.75401487
26MP0009333_abnormal_splenocyte_physiolog1.72442110
27MP0002398_abnormal_bone_marrow1.71098431
28MP0000703_abnormal_thymus_morphology1.69068003
29MP0004510_myositis1.67275359
30MP0003077_abnormal_cell_cycle1.67265259
31MP0008057_abnormal_DNA_replication1.64501951
32MP0002796_impaired_skin_barrier1.59443104
33MP0000678_abnormal_parathyroid_gland1.58810398
34MP0000858_altered_metastatic_potential1.57142819
35MP0005501_abnormal_skin_physiology1.57091394
36MP0003091_abnormal_cell_migration1.56395361
37MP0002249_abnormal_larynx_morphology1.54615444
38MP0005666_abnormal_adipose_tissue1.53907782
39MP0001800_abnormal_humoral_immune1.53467575
40MP0002139_abnormal_hepatobiliary_system1.51190129
41MP0002722_abnormal_immune_system1.50240595
42MP0002877_abnormal_melanocyte_morpholog1.49275988
43MP0000689_abnormal_spleen_morphology1.48768199
44MP0010307_abnormal_tumor_latency1.48314374
45MP0002405_respiratory_system_inflammati1.47759501
46MP0004233_abnormal_muscle_weight1.47227352
47MP0000465_gastrointestinal_hemorrhage1.40539745
48MP0005410_abnormal_fertilization1.40525936
49MP0000350_abnormal_cell_proliferation1.37942997
50MP0003984_embryonic_growth_retardation1.36704846
51MP0002088_abnormal_embryonic_growth/wei1.34111336
52MP0005380_embryogenesis_phenotype1.33481832
53MP0001672_abnormal_embryogenesis/_devel1.33481832
54MP0002086_abnormal_extraembryonic_tissu1.31772704
55MP0000609_abnormal_liver_physiology1.28842026
56MP0000716_abnormal_immune_system1.27578253
57MP0004858_abnormal_nervous_system1.26790081
58MP0002089_abnormal_postnatal_growth/wei1.26371826
59MP0005360_urolithiasis1.25795331
60MP0004381_abnormal_hair_follicle1.25223766
61MP0005083_abnormal_biliary_tract1.23637873
62MP0005464_abnormal_platelet_physiology1.23328457
63MP0001697_abnormal_embryo_size1.23284519
64MP0003191_abnormal_cellular_cholesterol1.22763984
65MP0001929_abnormal_gametogenesis1.22301519
66MP0002019_abnormal_tumor_incidence1.21958921
67MP0002429_abnormal_blood_cell1.21496631
68MP0005409_darkened_coat_color1.21344378
69MP0002084_abnormal_developmental_patter1.20716410
70MP0002166_altered_tumor_susceptibility1.20270925
71MP0000733_abnormal_muscle_development1.17590214
72MP0010094_abnormal_chromosome_stability1.17400574
73MP0000490_abnormal_crypts_of1.17188747
74MP0001348_abnormal_lacrimal_gland1.15709281
75MP0005000_abnormal_immune_tolerance1.14614054
76MP0002080_prenatal_lethality1.14513993
77MP0009053_abnormal_anal_canal1.14340725
78MP0005387_immune_system_phenotype1.13764521
79MP0001790_abnormal_immune_system1.13764521
80MP0003828_pulmonary_edema1.12979913
81MP0010155_abnormal_intestine_physiology1.11574726
82MP0005621_abnormal_cell_physiology1.11386568
83MP0002723_abnormal_immune_serum1.11109463
84MP0002420_abnormal_adaptive_immunity1.11056351
85MP0001873_stomach_inflammation1.10078191
86MP0001346_abnormal_lacrimal_gland1.10045650
87MP0010630_abnormal_cardiac_muscle1.08679927
88MP0002085_abnormal_embryonic_tissue1.08403347
89MP0001819_abnormal_immune_cell1.07665141
90MP0002452_abnormal_antigen_presenting1.06926177
91MP0002998_abnormal_bone_remodeling1.06057943
92MP0003172_abnormal_lysosome_physiology1.05834590
93MP0003566_abnormal_cell_adhesion1.05235045
94MP0005365_abnormal_bile_salt1.04867415
95MP0005375_adipose_tissue_phenotype1.04659154
96MP0004197_abnormal_fetal_growth/weight/1.03745216
97MP0004947_skin_inflammation1.02553258
98MP0000313_abnormal_cell_death1.02048799
99MP0008877_abnormal_DNA_methylation1.01661610
100MP0000537_abnormal_urethra_morphology1.01142267
101MP0008007_abnormal_cellular_replicative0.99620258
102MP0010234_abnormal_vibrissa_follicle0.99573644
103MP0010030_abnormal_orbit_morphology0.99394565
104MP0005670_abnormal_white_adipose0.98755685
105MP0001835_abnormal_antigen_presentation0.97386196
106MP0002419_abnormal_innate_immunity0.96522241
107MP0000003_abnormal_adipose_tissue0.95208622
108MP0003866_abnormal_defecation0.94776725
109MP0008004_abnormal_stomach_pH0.94363673
110MP0008770_decreased_survivor_rate0.94158346
111MP0000681_abnormal_thyroid_gland0.92354815
112MP0000598_abnormal_liver_morphology0.92104635
113MP0003646_muscle_fatigue0.91901566
114MP0004264_abnormal_extraembryonic_tissu0.91301687
115MP0005025_abnormal_response_to0.91219826
116MP0009931_abnormal_skin_appearance0.89970404
117MP0003453_abnormal_keratinocyte_physiol0.89924103
118MP0001915_intracranial_hemorrhage0.89460198
119MP0008932_abnormal_embryonic_tissue0.89460131
120MP0002138_abnormal_hepatobiliary_system0.89208244
121MP0002132_abnormal_respiratory_system0.89165579
122MP0004084_abnormal_cardiac_muscle0.89149441
123MP0001851_eye_inflammation0.88923207
124MP0002210_abnormal_sex_determination0.88676285
125MP0008995_early_reproductive_senescence0.87199858
126MP0002060_abnormal_skin_morphology0.86547021
127MP0001533_abnormal_skeleton_physiology0.85877497
128MP0002925_abnormal_cardiovascular_devel0.85811034
129MP0001216_abnormal_epidermal_layer0.84587789
130MP0009672_abnormal_birth_weight0.84013289
131MP0002009_preneoplasia0.83771262
132MP0001145_abnormal_male_reproductive0.82857783
133MP0005023_abnormal_wound_healing0.82626942
134MP0005671_abnormal_response_to0.80735770
135MP0003436_decreased_susceptibility_to0.79276663
136MP0003698_abnormal_male_reproductive0.77426165
137MP0010329_abnormal_lipoprotein_level0.77301727
138MP0000477_abnormal_intestine_morphology0.76724249

Predicted human phenotypes

RankGene SetZ-score
1Nasal polyposis (HP:0100582)4.86890522
2Abnormality of the nasal mucosa (HP:0000433)4.53808499
3Abnormality of the fingertips (HP:0001211)3.93468260
4Purpura (HP:0000979)3.38132790
5Polycythemia (HP:0001901)3.12662941
6Basal cell carcinoma (HP:0002671)3.12020963
7Male infertility (HP:0003251)3.04457906
8Menorrhagia (HP:0000132)2.83096489
9Hyperacusis (HP:0010780)2.78531996
10Colitis (HP:0002583)2.77751755
11Abnormal platelet function (HP:0011869)2.76017967
12Impaired platelet aggregation (HP:0003540)2.76017967
13Verrucae (HP:0200043)2.69221879
14Papilloma (HP:0012740)2.69221879
15Cerebral aneurysm (HP:0004944)2.62477388
16Gastrointestinal inflammation (HP:0004386)2.61580323
17Abnormality of the lower motor neuron (HP:0002366)2.59871741
18Multiple enchondromatosis (HP:0005701)2.57995464
19Recurrent bronchitis (HP:0002837)2.57802226
20Obstructive sleep apnea (HP:0002870)2.57142471
21Abnormality of the distal phalanges of the toes (HP:0010182)2.55302910
22Distal lower limb amyotrophy (HP:0008944)2.55033456
23Progressive muscle weakness (HP:0003323)2.52484755
24Heterotopia (HP:0002282)2.52119693
25Distal lower limb muscle weakness (HP:0009053)2.46906103
26Increased density of long bones (HP:0006392)2.45679877
27Ulnar bowing (HP:0003031)2.44398438
28Broad distal phalanx of finger (HP:0009836)2.44203676
29Spontaneous hematomas (HP:0007420)2.41863807
30Thrombocytosis (HP:0001894)2.41145053
31T lymphocytopenia (HP:0005403)2.39860055
32Septate vagina (HP:0001153)2.39786844
33Prominent nose (HP:0000448)2.39290084
34Fatigue (HP:0012378)2.38383972
35Ependymoma (HP:0002888)2.35211113
36Inflammation of the large intestine (HP:0002037)2.34415739
37Squamous cell carcinoma (HP:0002860)2.33746809
38Macroorchidism (HP:0000053)2.30045932
39Broad face (HP:0000283)2.28543752
40Pseudobulbar signs (HP:0002200)2.25303230
41Hypercortisolism (HP:0001578)2.23320198
42Petechiae (HP:0000967)2.22935547
43Increased connective tissue (HP:0009025)2.22117185
44Vertebral compression fractures (HP:0002953)2.22099349
45Bronchitis (HP:0012387)2.20516656
46Abnormality of cells of the erythroid lineage (HP:0012130)2.20020594
47IgM deficiency (HP:0002850)2.19381259
48Hyperparathyroidism (HP:0000843)2.18073668
49Eczematoid dermatitis (HP:0000976)2.18068364
50Mitral valve prolapse (HP:0001634)2.16876904
51Deep palmar crease (HP:0006191)2.16511693
52Rectal prolapse (HP:0002035)2.15985778
53Prolonged bleeding time (HP:0003010)2.14611414
54Abnormality of T cell number (HP:0011839)2.13945773
55Abnormality of the distal phalanx of the thumb (HP:0009617)2.13548196
56Thin bony cortex (HP:0002753)2.13265679
57Recurrent viral infections (HP:0004429)2.10266509
58Progressive external ophthalmoplegia (HP:0000590)2.07766009
59Abnormal delayed hypersensitivity skin test (HP:0002963)2.07476068
60Abnormal platelet volume (HP:0011876)2.06598868
61Trismus (HP:0000211)2.06426708
62Abnormality of macrophages (HP:0004311)2.05697159
63Centrally nucleated skeletal muscle fibers (HP:0003687)2.04594293
64Disproportionate tall stature (HP:0001519)2.04572508
65Long palpebral fissure (HP:0000637)2.03755414
66Persistence of primary teeth (HP:0006335)2.03356878
67Abnormal gallbladder physiology (HP:0012438)2.02178281
68Cholecystitis (HP:0001082)2.02178281
69Abnormality of the Achilles tendon (HP:0005109)2.01346598
70Achilles tendon contracture (HP:0001771)2.01296323
71Hand muscle atrophy (HP:0009130)2.00508241
72Distal upper limb amyotrophy (HP:0007149)2.00477054
73Upper limb amyotrophy (HP:0009129)2.00477054
74Ragged-red muscle fibers (HP:0003200)2.00325722
75Hemorrhage of the eye (HP:0011885)2.00154348
76Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.99935335
77Chronic otitis media (HP:0000389)1.97786924
78Increased mean platelet volume (HP:0011877)1.96882644
79Deep venous thrombosis (HP:0002625)1.96340421
80Asymmetry of the thorax (HP:0001555)1.95635211
81Hematochezia (HP:0002573)1.95611965
82High pitched voice (HP:0001620)1.95182928
83Infertility (HP:0000789)1.94727847
84Increased serum ferritin (HP:0003281)1.93617133
85Panhypogammaglobulinemia (HP:0003139)1.93358024
86Abnormality of the phalanges of the hallux (HP:0010057)1.93169664
87Neoplasm of striated muscle (HP:0009728)1.92932238
88Atrioventricular block (HP:0001678)1.92312356
89Abnormality of the thoracic spine (HP:0100711)1.92081200
90Cellulitis (HP:0100658)1.92066968
91Aneurysm (HP:0002617)1.91585979
92Cutaneous melanoma (HP:0012056)1.91439210
93Abnormal number of erythroid precursors (HP:0012131)1.90885001
94Sparse lateral eyebrow (HP:0005338)1.90732694
95Flat acetabular roof (HP:0003180)1.90688243
96Abnormality of T cells (HP:0002843)1.89495482
97Recurrent sinusitis (HP:0011108)1.88781192
98Global brain atrophy (HP:0002283)1.88522748
99Dysmetric saccades (HP:0000641)1.87943006
100Bronchiectasis (HP:0002110)1.87334474
101Genu recurvatum (HP:0002816)1.87034439
102Ankyloglossia (HP:0010296)1.86567368
103Asymmetric septal hypertrophy (HP:0001670)1.86300371
104Back pain (HP:0003418)1.85841509
105Abnormal large intestine physiology (HP:0012700)1.84320981
106Recurrent otitis media (HP:0000403)1.83597088
107Interstitial pulmonary disease (HP:0006530)1.82890073
108Insomnia (HP:0100785)1.82184572
109Long eyelashes (HP:0000527)1.81063462
110Selective tooth agenesis (HP:0001592)1.80527999
111Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.80485506
112Short 4th metacarpal (HP:0010044)1.80485506
113Skin tags (HP:0010609)1.80170666
114Recurrent abscess formation (HP:0002722)1.79960514
115Facial hemangioma (HP:0000329)1.79722163
116Hypertensive crisis (HP:0100735)1.79067418
117Breast hypoplasia (HP:0003187)1.78657732
118Reticulocytosis (HP:0001923)1.77226967
119Rhabdomyosarcoma (HP:0002859)1.75625569
120Dysostosis multiplex (HP:0000943)1.74200186
121Truncus arteriosus (HP:0001660)1.74084759
122Epistaxis (HP:0000421)1.74023128
123Enlarged penis (HP:0000040)1.73300754
124Hypochromic anemia (HP:0001931)1.73295153
125Bowel incontinence (HP:0002607)1.73290536
126Abnormality of the 4th metacarpal (HP:0010012)1.73268773
127Impulsivity (HP:0100710)1.73153695
128Spinal cord lesions (HP:0100561)1.72551681
129Syringomyelia (HP:0003396)1.72551681
130Increased cerebral lipofuscin (HP:0011813)1.72483528
131Fibroma (HP:0010614)1.71315142
132Chest pain (HP:0100749)1.71170652
133Pustule (HP:0200039)1.70708841
134Renal cell carcinoma (HP:0005584)1.70521785
135Hyperthyroidism (HP:0000836)1.69323036
136Polygenic inheritance (HP:0010982)1.69310026
137Gastrointestinal stroma tumor (HP:0100723)1.68266065
138Dislocated radial head (HP:0003083)1.67877019
139Medulloblastoma (HP:0002885)1.67776137
140Uterine leiomyosarcoma (HP:0002891)1.67241067
141Leiomyosarcoma (HP:0100243)1.67241067
142Recurrent bacterial skin infections (HP:0005406)1.67150001
143Gout (HP:0001997)1.67023401
144Increased nuchal translucency (HP:0010880)1.66999947
145Neoplasm of the oral cavity (HP:0100649)1.66624163
146Recurrent fungal infections (HP:0002841)1.66001497
147Cafe-au-lait spot (HP:0000957)1.65911936
148Malnutrition (HP:0004395)1.65881442
149Angiofibromas (HP:0010615)1.65777349
150Adenoma sebaceum (HP:0009720)1.65777349
151Bicuspid aortic valve (HP:0001647)1.65370684
152Bone pain (HP:0002653)1.64787068
153Chronic bronchitis (HP:0004469)1.64588300
154Emphysema (HP:0002097)1.64258450
155Overlapping toe (HP:0001845)1.63359434
156Increased variability in muscle fiber diameter (HP:0003557)1.63186922
157Premature skin wrinkling (HP:0100678)1.63052130
158Amaurosis fugax (HP:0100576)1.63007099
159Chronic obstructive pulmonary disease (HP:0006510)1.62932527
160Obstructive lung disease (HP:0006536)1.62932527
161Ankle contracture (HP:0006466)1.62759045
162Annular pancreas (HP:0001734)1.62668673
163Protrusio acetabuli (HP:0003179)1.62667958
164Abnormality of skeletal muscle fiber size (HP:0012084)1.62600522
165Abnormality of oral frenula (HP:0000190)1.60777591
166Difficulty climbing stairs (HP:0003551)1.60729363
167Loss of speech (HP:0002371)1.58555301
168Abnormality of the umbilical cord (HP:0010881)1.58529081
169Spinal cord compression (HP:0002176)1.57423416
170Increased neuronal autofluorescent lipopigment (HP:0002074)1.56946371
171Aplasia/Hypoplasia of the sacrum (HP:0008517)1.56489454
172Hypertriglyceridemia (HP:0002155)1.56387191
173Mitral regurgitation (HP:0001653)1.56384260
174Patellar dislocation (HP:0002999)1.56355840
175Abnormality of the radial head (HP:0003995)1.55850467
176Abnormal ossification of hand bones (HP:0005921)1.55271485
177Lower limb amyotrophy (HP:0007210)1.54338080
178Pointed chin (HP:0000307)1.53317105
179Hepatosplenomegaly (HP:0001433)1.53184558

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.32335527
2SMG14.08802493
3TRIB33.99881590
4CDK123.70555702
5PRPF4B3.22092783
6IRAK33.21247078
7MAP4K13.17977438
8PKN23.06973565
9MAP3K102.88441351
10ICK2.72381425
11NME22.31791379
12NEK22.23912323
13GRK62.09681536
14RIPK41.95330886
15ERN11.87679500
16STK101.82753402
17TAOK11.64388123
18TAOK21.61052344
19PRKD31.54782924
20CDC71.52406295
21TYK21.34587858
22MAP3K31.34042973
23TYRO31.31782689
24CDK41.30402492
25LRRK21.29911116
26TAOK31.29240887
27PTK61.24584499
28TESK21.23028911
29PRKD21.22866995
30EPHA21.22017248
31ZAP701.21954794
32TTN1.19423405
33IRAK41.15892622
34ARAF1.12152223
35IRAK21.11869045
36MTOR1.11512494
37ALK1.11154617
38BRD41.09986112
39MAP2K21.05130278
40TGFBR21.02243801
41STK31.02235214
42PAK41.02213493
43RPS6KB21.00273164
44CDK71.00032944
45EPHB10.99494809
46SIK10.99400544
47PDGFRA0.97926693
48MAP3K60.96617061
49FGFR40.96117990
50HIPK20.95973957
51MAP2K30.95890305
52PIM10.95862398
53PDK40.95048386
54PDK30.95048386
55BMX0.94050798
56LATS10.91658352
57RIPK10.89338543
58CDK60.88345591
59CDC42BPA0.88149491
60PDGFRB0.87051013
61RPS6KA40.86620072
62MAP3K70.85507320
63PIM20.84194595
64MAP3K80.83373910
65KSR20.83298018
66CDK90.81916416
67MARK30.80581811
68BTK0.80513008
69CSF1R0.80467244
70ITK0.80403588
71AURKA0.80293081
72FLT30.80127700
73JAK30.79498431
74SIK20.79025047
75BRAF0.78363631
76MST1R0.77878840
77JAK10.77098769
78MAP3K140.76903754
79HCK0.75992113
80NLK0.75290354
81CAMK1D0.71301630
82MAP3K110.70408221
83MARK20.70311288
84DYRK30.68542602
85PDK10.66586902
86SIK30.66309982
87LATS20.66177145
88PRKCH0.64809104
89STK40.64679832
90ILK0.64678479
91BUB10.64314590
92RPS6KL10.64245085
93RPS6KC10.64245085
94MAPKAPK30.64067870
95TNK20.63742320
96CAMK1G0.63120986
97CSK0.63098548
98TTK0.62705731
99MELK0.61810437
100MAPK110.61276784
101RPS6KA20.61045416
102PAK20.60406338
103JAK20.60361953
104RET0.59655289
105KIT0.58760181
106FGFR30.56560783
107LMTK20.56189633
108PASK0.55214796
109SCYL20.54468928
110CHUK0.53827303
111IKBKB0.53763781
112PAK10.53586432
113BLK0.51085960
114CHEK10.50624769
115RAF10.49567675
116PDPK10.49530653
117LCK0.49145942
118MAPK120.47502723
119MATK0.47467897
120DYRK1B0.47466261
121MAP3K90.45230357
122RPS6KA10.44665302
123TBK10.44214851
124EIF2AK10.43804345
125CDK20.43553002
126PTK20.43207544
127MAP3K130.43163620
128CHEK20.43122240
129STK380.43000131
130AKT20.42007995
131MAPKAPK20.41354613
132PRKD10.40429539
133RPS6KA60.39472547
134DMPK0.39443867
135TESK10.39313006
136STK110.37955362
137TGFBR10.37444581
138BCKDK0.36941369
139PRKAA10.36559710
140MAP3K10.36309241

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.28743626
2Acute myeloid leukemia_Homo sapiens_hsa052212.05575167
3Notch signaling pathway_Homo sapiens_hsa043302.02334195
4Primary immunodeficiency_Homo sapiens_hsa053401.98491129
5Chronic myeloid leukemia_Homo sapiens_hsa052201.95710140
6Nitrogen metabolism_Homo sapiens_hsa009101.89564881
7mTOR signaling pathway_Homo sapiens_hsa041501.77815254
8Other glycan degradation_Homo sapiens_hsa005111.76808538
9Lysine degradation_Homo sapiens_hsa003101.75478304
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.72948117
11Sulfur relay system_Homo sapiens_hsa041221.68138802
12Insulin resistance_Homo sapiens_hsa049311.59251188
13T cell receptor signaling pathway_Homo sapiens_hsa046601.53001295
14Non-small cell lung cancer_Homo sapiens_hsa052231.48944044
15VEGF signaling pathway_Homo sapiens_hsa043701.48237296
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.48091047
17mRNA surveillance pathway_Homo sapiens_hsa030151.48059674
18Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.46076926
19Toll-like receptor signaling pathway_Homo sapiens_hsa046201.44394581
20Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.35164798
21Pentose phosphate pathway_Homo sapiens_hsa000301.34855348
22Osteoclast differentiation_Homo sapiens_hsa043801.34723382
23DNA replication_Homo sapiens_hsa030301.32363750
24Small cell lung cancer_Homo sapiens_hsa052221.29458738
25Central carbon metabolism in cancer_Homo sapiens_hsa052301.29424053
26Pancreatic cancer_Homo sapiens_hsa052121.29151364
27Antigen processing and presentation_Homo sapiens_hsa046121.27871996
28Mismatch repair_Homo sapiens_hsa034301.27448576
29Spliceosome_Homo sapiens_hsa030401.27189359
30Longevity regulating pathway - mammal_Homo sapiens_hsa042111.26186191
31Colorectal cancer_Homo sapiens_hsa052101.24862713
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.24719062
33Thyroid cancer_Homo sapiens_hsa052161.23568178
34Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.20262375
35Prolactin signaling pathway_Homo sapiens_hsa049171.19136213
36RNA transport_Homo sapiens_hsa030131.19031584
37Thyroid hormone signaling pathway_Homo sapiens_hsa049191.18687761
38Adipocytokine signaling pathway_Homo sapiens_hsa049201.15542466
39HTLV-I infection_Homo sapiens_hsa051661.14925045
40Prion diseases_Homo sapiens_hsa050201.13219733
41Transcriptional misregulation in cancer_Homo sapiens_hsa052021.12772730
42Hepatitis B_Homo sapiens_hsa051611.11984187
43Endometrial cancer_Homo sapiens_hsa052131.11469124
44Hepatitis C_Homo sapiens_hsa051601.10982726
45Glycosaminoglycan degradation_Homo sapiens_hsa005311.09487659
46Cell cycle_Homo sapiens_hsa041101.08695480
47Base excision repair_Homo sapiens_hsa034101.08590301
48Herpes simplex infection_Homo sapiens_hsa051681.08227905
49Arginine biosynthesis_Homo sapiens_hsa002201.04652402
50Dorso-ventral axis formation_Homo sapiens_hsa043201.04118608
51Biosynthesis of amino acids_Homo sapiens_hsa012301.03868075
52ErbB signaling pathway_Homo sapiens_hsa040121.02026949
53Shigellosis_Homo sapiens_hsa051311.01850568
54Viral carcinogenesis_Homo sapiens_hsa052030.99100445
55MicroRNAs in cancer_Homo sapiens_hsa052060.98868328
56AMPK signaling pathway_Homo sapiens_hsa041520.98405790
57Glucagon signaling pathway_Homo sapiens_hsa049220.98263755
58Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.98176972
59TNF signaling pathway_Homo sapiens_hsa046680.96671075
60Toxoplasmosis_Homo sapiens_hsa051450.95129174
61Estrogen signaling pathway_Homo sapiens_hsa049150.94485677
62Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.93998319
63Renal cell carcinoma_Homo sapiens_hsa052110.91981389
64Ribosome_Homo sapiens_hsa030100.91679076
65Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91346143
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.90108419
67Measles_Homo sapiens_hsa051620.89384231
68Carbohydrate digestion and absorption_Homo sapiens_hsa049730.89271056
69Prostate cancer_Homo sapiens_hsa052150.88199164
70Insulin signaling pathway_Homo sapiens_hsa049100.87341388
71Epstein-Barr virus infection_Homo sapiens_hsa051690.86589719
72Fructose and mannose metabolism_Homo sapiens_hsa000510.85984638
73Platelet activation_Homo sapiens_hsa046110.85212063
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.84755413
75FoxO signaling pathway_Homo sapiens_hsa040680.84349490
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.83941320
77Inositol phosphate metabolism_Homo sapiens_hsa005620.83926014
78Endocytosis_Homo sapiens_hsa041440.83860134
79Chemokine signaling pathway_Homo sapiens_hsa040620.82738322
80AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.82688095
81Apoptosis_Homo sapiens_hsa042100.82314476
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.82188104
83RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.82033996
84Bladder cancer_Homo sapiens_hsa052190.80546576
85Galactose metabolism_Homo sapiens_hsa000520.80259986
86One carbon pool by folate_Homo sapiens_hsa006700.80135103
87Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.79574913
88Vitamin B6 metabolism_Homo sapiens_hsa007500.79003303
89Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.77543435
90Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.76656794
91Systemic lupus erythematosus_Homo sapiens_hsa053220.76101743
92Leukocyte transendothelial migration_Homo sapiens_hsa046700.74312902
93Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.73824585
942-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.73368387
95Cysteine and methionine metabolism_Homo sapiens_hsa002700.72800649
96ABC transporters_Homo sapiens_hsa020100.69925624
97HIF-1 signaling pathway_Homo sapiens_hsa040660.69288786
98NF-kappa B signaling pathway_Homo sapiens_hsa040640.68674562
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.68388099
100Selenocompound metabolism_Homo sapiens_hsa004500.67746789
101Tuberculosis_Homo sapiens_hsa051520.66336213
102Melanoma_Homo sapiens_hsa052180.66204167
103Amoebiasis_Homo sapiens_hsa051460.64832910
104Focal adhesion_Homo sapiens_hsa045100.64762468
105Sphingolipid signaling pathway_Homo sapiens_hsa040710.64110468
106Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63046023
107Bile secretion_Homo sapiens_hsa049760.62719216
108Lysosome_Homo sapiens_hsa041420.62074752
109Glioma_Homo sapiens_hsa052140.60672341
110Influenza A_Homo sapiens_hsa051640.60545599
111Viral myocarditis_Homo sapiens_hsa054160.59667544
112GnRH signaling pathway_Homo sapiens_hsa049120.59554349
113Carbon metabolism_Homo sapiens_hsa012000.59490444
114p53 signaling pathway_Homo sapiens_hsa041150.58729970
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57904279
116Adherens junction_Homo sapiens_hsa045200.57209859
117Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.56854077
118Alcoholism_Homo sapiens_hsa050340.55686347
119Fatty acid biosynthesis_Homo sapiens_hsa000610.55018525
120Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.54311780
121Gap junction_Homo sapiens_hsa045400.53861650
122Folate biosynthesis_Homo sapiens_hsa007900.53633807
123Intestinal immune network for IgA production_Homo sapiens_hsa046720.53005156
124Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.52716704
125Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.52680592
126Choline metabolism in cancer_Homo sapiens_hsa052310.52289322
127Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51181716
128Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.50964398
129Proteoglycans in cancer_Homo sapiens_hsa052050.50759020
130Regulation of actin cytoskeleton_Homo sapiens_hsa048100.50734008
131Pathways in cancer_Homo sapiens_hsa052000.50255966
132Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.49577330
133Leishmaniasis_Homo sapiens_hsa051400.48602215
134RNA degradation_Homo sapiens_hsa030180.48565752
135Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48077662

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