METAP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1purine nucleobase biosynthetic process (GO:0009113)5.84612608
2nucleobase biosynthetic process (GO:0046112)5.73803367
3folic acid-containing compound biosynthetic process (GO:0009396)5.27868681
4establishment of integrated proviral latency (GO:0075713)5.11682216
5formation of translation preinitiation complex (GO:0001731)4.84749694
6IMP biosynthetic process (GO:0006188)4.80518355
7DNA strand renaturation (GO:0000733)4.58239307
8ribosome assembly (GO:0042255)4.46480339
9mitotic sister chromatid cohesion (GO:0007064)4.45545077
10nuclear pore organization (GO:0006999)4.42302655
11IMP metabolic process (GO:0046040)4.41992441
12nuclear pore complex assembly (GO:0051292)4.31016438
13histone-serine phosphorylation (GO:0035404)4.10950335
14regulation of translational termination (GO:0006449)4.05424414
15mitotic metaphase plate congression (GO:0007080)4.03703899
16CENP-A containing nucleosome assembly (GO:0034080)4.00112607
17folic acid metabolic process (GO:0046655)3.96852023
18double-strand break repair via nonhomologous end joining (GO:0006303)3.95486191
19non-recombinational repair (GO:0000726)3.95486191
20establishment of viral latency (GO:0019043)3.88784217
21mitotic nuclear envelope disassembly (GO:0007077)3.85965366
22regulation of helicase activity (GO:0051095)3.74103906
23ribosome biogenesis (GO:0042254)3.69226711
24DNA unwinding involved in DNA replication (GO:0006268)3.68885196
25kinetochore organization (GO:0051383)3.68432159
26nuclear envelope disassembly (GO:0051081)3.64209051
27membrane disassembly (GO:0030397)3.64209051
28tetrahydrofolate metabolic process (GO:0046653)3.64170999
29DNA replication checkpoint (GO:0000076)3.61057835
30histone exchange (GO:0043486)3.60789670
31kinetochore assembly (GO:0051382)3.60129061
32regulation of centriole replication (GO:0046599)3.59558950
33telomere maintenance via recombination (GO:0000722)3.56763661
34protein localization to kinetochore (GO:0034501)3.55149038
35DNA replication initiation (GO:0006270)3.51634499
36DNA ligation (GO:0006266)3.47233468
37negative regulation of mitotic sister chromatid separation (GO:2000816)3.46162650
38negative regulation of sister chromatid segregation (GO:0033046)3.46162650
39negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.46162650
40negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.46162650
41negative regulation of mitotic sister chromatid segregation (GO:0033048)3.46162650
42proteasome assembly (GO:0043248)3.44846122
43DNA replication-dependent nucleosome assembly (GO:0006335)3.44241758
44DNA replication-dependent nucleosome organization (GO:0034723)3.44241758
45DNA double-strand break processing (GO:0000729)3.42472908
46tRNA aminoacylation (GO:0043039)3.42350685
47amino acid activation (GO:0043038)3.42350685
48regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.36921504
49regulation of RNA export from nucleus (GO:0046831)3.36802490
50DNA strand elongation involved in DNA replication (GO:0006271)3.36181642
51pteridine-containing compound biosynthetic process (GO:0042559)3.31593285
52metaphase plate congression (GO:0051310)3.31492117
53folic acid-containing compound metabolic process (GO:0006760)3.31008095
54regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.26614253
55regulation of spindle organization (GO:0090224)3.25714382
56spindle assembly checkpoint (GO:0071173)3.24711097
57protein complex localization (GO:0031503)3.21264031
58regulation of mitotic sister chromatid separation (GO:0010965)3.20854905
59regulation of mitotic sister chromatid segregation (GO:0033047)3.20854905
60regulation of sister chromatid segregation (GO:0033045)3.20854905
61chaperone-mediated protein complex assembly (GO:0051131)3.20763165
62regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.20132316
63telomere maintenance via telomere lengthening (GO:0010833)3.17363105
64regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.17210369
65regulation of mitotic spindle checkpoint (GO:1903504)3.17210369
66transcription from mitochondrial promoter (GO:0006390)3.16725892
67maturation of SSU-rRNA (GO:0030490)3.13184451
68negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.13119245
69negative regulation of ligase activity (GO:0051352)3.13119245
70DNA strand elongation (GO:0022616)3.12467872
71DNA duplex unwinding (GO:0032508)3.12016449
72DNA geometric change (GO:0032392)3.11685041
73regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.11597259
74response to X-ray (GO:0010165)3.09389727
75glycine metabolic process (GO:0006544)3.07410666
76somatic diversification of immune receptors via somatic mutation (GO:0002566)3.07021186
77somatic hypermutation of immunoglobulin genes (GO:0016446)3.07021186
78mitotic chromosome condensation (GO:0007076)3.05897001
79regulation of gene silencing by RNA (GO:0060966)3.05602830
80regulation of posttranscriptional gene silencing (GO:0060147)3.05602830
81regulation of gene silencing by miRNA (GO:0060964)3.05602830
82somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.03504835
83somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.03504835
84isotype switching (GO:0045190)3.03504835
85ribonucleoprotein complex biogenesis (GO:0022613)3.03311975
86protein deneddylation (GO:0000338)3.02489292
87regulation of translation in response to stress (GO:0043555)3.01918935
88pore complex assembly (GO:0046931)3.01254899
89negative regulation of mRNA processing (GO:0050686)3.01077682
90DNA topological change (GO:0006265)3.00115152
91positive regulation of chromosome segregation (GO:0051984)3.00093726
92negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.99462393
93L-serine metabolic process (GO:0006563)2.98817815
94negative regulation of mRNA metabolic process (GO:1903312)2.98624494
95regulation of mitotic spindle organization (GO:0060236)2.97197173
96RNA-dependent DNA replication (GO:0006278)2.97164877
97ribosomal large subunit biogenesis (GO:0042273)2.95764569
98nuclear envelope organization (GO:0006998)2.95128718
99pre-miRNA processing (GO:0031054)2.93635998
100DNA catabolic process, exonucleolytic (GO:0000738)2.93266682
101telomere maintenance via telomerase (GO:0007004)2.92343412
102replication fork processing (GO:0031297)2.91141481
103DNA damage response, detection of DNA damage (GO:0042769)2.90751481
104ATP-dependent chromatin remodeling (GO:0043044)2.90748519
105one-carbon metabolic process (GO:0006730)2.89301808
106establishment of chromosome localization (GO:0051303)2.88954949
107regulation of centrosome cycle (GO:0046605)2.87885925
108nucleobase-containing small molecule interconversion (GO:0015949)2.86128399
109mitotic spindle checkpoint (GO:0071174)2.84760687
110mitotic sister chromatid segregation (GO:0000070)2.84557955
111spindle checkpoint (GO:0031577)2.83557529
112protein localization to chromosome, centromeric region (GO:0071459)2.83154816
113regulation of mitochondrial translation (GO:0070129)2.78654066
114maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.76685454
115rRNA processing (GO:0006364)2.76606012
116pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.76011492
117spliceosomal snRNP assembly (GO:0000387)2.74981881
118regulation of chromosome segregation (GO:0051983)2.74627420
119cullin deneddylation (GO:0010388)2.73403686
120tRNA aminoacylation for protein translation (GO:0006418)2.73280057
121regulation of translational initiation (GO:0006446)2.73099371
122regulation of translational fidelity (GO:0006450)2.72535880
123rRNA modification (GO:0000154)2.72379114
124telomere maintenance via semi-conservative replication (GO:0032201)2.71583583
125pteridine-containing compound metabolic process (GO:0042558)2.71531101
126positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.71470669
127cell cycle G1/S phase transition (GO:0044843)2.71074046
128G1/S transition of mitotic cell cycle (GO:0000082)2.71074046
129anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.70138714
130regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.69549000
131interferon-gamma secretion (GO:0072643)2.69174699
132sister chromatid segregation (GO:0000819)2.68770999
133pseudouridine synthesis (GO:0001522)2.66604877
134chromatin remodeling at centromere (GO:0031055)2.65972643
135maturation of 5.8S rRNA (GO:0000460)2.65559590
136mitotic recombination (GO:0006312)2.65333665
137rRNA metabolic process (GO:0016072)2.65095108
138DNA replication-independent nucleosome assembly (GO:0006336)2.64509271
139DNA replication-independent nucleosome organization (GO:0034724)2.64509271
140negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.63688023
141pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.63611581
142UMP biosynthetic process (GO:0006222)2.63611581
143pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.63611581
144UMP metabolic process (GO:0046049)2.63611581
145regulation of mitotic metaphase/anaphase transition (GO:0030071)2.62740585
146mitotic spindle assembly checkpoint (GO:0007094)2.62710094
147regulation of sister chromatid cohesion (GO:0007063)2.62527607
148negative regulation of chromosome segregation (GO:0051985)2.62329643

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.45034539
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.26554286
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.57698668
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.39419682
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.25838117
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.93461616
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.90642407
8RBPJ_22232070_ChIP-Seq_NCS_Mouse2.89804880
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.85291840
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.78079744
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.72574957
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.65398327
13FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.64077637
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.63409622
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.58481412
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.52974258
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.49634211
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.34944545
19* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.27806801
20* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.21539224
21* MYCN_18555785_ChIP-Seq_MESCs_Mouse2.15765941
22* VDR_23849224_ChIP-Seq_CD4+_Human2.09847510
23AR_21909140_ChIP-Seq_LNCAP_Human2.07324369
24PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.04517810
25XRN2_22483619_ChIP-Seq_HELA_Human2.03643932
26POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.01580138
27MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.98886315
28* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.96528797
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.95187756
30FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.91845503
31E2F1_21310950_ChIP-Seq_MCF-7_Human1.90326876
32GABP_19822575_ChIP-Seq_HepG2_Human1.85989992
33DCP1A_22483619_ChIP-Seq_HELA_Human1.82924815
34ELK1_19687146_ChIP-ChIP_HELA_Human1.82277186
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.71990060
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.69523555
37* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.67393529
38NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.66306415
39YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.65046092
40FOXP3_21729870_ChIP-Seq_TREG_Human1.65015991
41KDM5A_27292631_Chip-Seq_BREAST_Human1.61413408
42ELF1_17652178_ChIP-ChIP_JURKAT_Human1.57338033
43TFEB_21752829_ChIP-Seq_HELA_Human1.56773808
44E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.55274996
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.52136533
46KLF4_18555785_ChIP-Seq_MESCs_Mouse1.51801783
47STAT3_1855785_ChIP-Seq_MESCs_Mouse1.51634564
48ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.51273776
49TTF2_22483619_ChIP-Seq_HELA_Human1.48250109
50POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.46304608
51ZNF263_19887448_ChIP-Seq_K562_Human1.43599779
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.42977121
53SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.41014325
54HOXB4_20404135_ChIP-ChIP_EML_Mouse1.36305281
55HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.34877958
56NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.32555202
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.31668056
58SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.28279448
59* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.28237722
60YY1_21170310_ChIP-Seq_MESCs_Mouse1.27755465
61MYC_18940864_ChIP-ChIP_HL60_Human1.27754247
62SALL1_21062744_ChIP-ChIP_HESCs_Human1.27372687
63MYC_22102868_ChIP-Seq_BL_Human1.26396324
64NANOG_16153702_ChIP-ChIP_HESCs_Human1.25850682
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25412463
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.24653771
67CIITA_25753668_ChIP-Seq_RAJI_Human1.21561228
68TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.18934333
69DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.15551140
70ERG_20887958_ChIP-Seq_HPC-7_Mouse1.13127518
71CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.12993851
72* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10022996
73CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.09081031
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08093744
75E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08056510
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.07865838
77NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.04904217
78PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.04346558
79CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.04152201
80KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.03024512
81SOX2_18555785_ChIP-Seq_MESCs_Mouse1.02890190
82HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.01423356
83ESR1_15608294_ChIP-ChIP_MCF-7_Human1.01343020
84CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99292607
85CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.98833511
86SRF_21415370_ChIP-Seq_HL-1_Mouse0.98793040
87ELK1_22589737_ChIP-Seq_MCF10A_Human0.98346229
88MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.98270454
89NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.96277760
90SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.95561203
91PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.95284329
92* EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.94825553
93SOX17_20123909_ChIP-Seq_XEN_Mouse0.94047875
94NANOG_21062744_ChIP-ChIP_HESCs_Human0.93794439
95CHD1_26751641_Chip-Seq_LNCaP_Human0.93778836
96EWS_26573619_Chip-Seq_HEK293_Human0.92893936
97PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.91897698
98FUS_26573619_Chip-Seq_HEK293_Human0.90582362
99* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.90574613
100BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.89764776
101ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.89749887
102DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89333127
103CLOCK_20551151_ChIP-Seq_293T_Human0.88793680
104SOX2_16153702_ChIP-ChIP_HESCs_Human0.88537058
105FLI1_27457419_Chip-Seq_LIVER_Mouse0.87603583
106SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.85669237
107* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.85232705
108CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.85155931
109TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.83486234
110HIF1A_21447827_ChIP-Seq_MCF-7_Human0.83423698
111NOTCH1_21737748_ChIP-Seq_TLL_Human0.81390637
112POU5F1_16153702_ChIP-ChIP_HESCs_Human0.80990353
113NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.79473129
114HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.79454553
115TCF3_18692474_ChIP-Seq_MEFs_Mouse0.75297568
116PCGF2_27294783_Chip-Seq_ESCs_Mouse0.73912695
117GATA4_21415370_ChIP-Seq_HL-1_Mouse0.72662762
118KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.71644560
119KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.71644560

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.71248507
2MP0004957_abnormal_blastocyst_morpholog3.76666726
3MP0003111_abnormal_nucleus_morphology3.51994552
4MP0010094_abnormal_chromosome_stability3.43504913
5MP0003077_abnormal_cell_cycle3.33495336
6MP0003806_abnormal_nucleotide_metabolis3.05728957
7MP0010352_gastrointestinal_tract_polyps3.03067316
8MP0001730_embryonic_growth_arrest2.85269414
9MP0008057_abnormal_DNA_replication2.80722242
10MP0010234_abnormal_vibrissa_follicle2.65752437
11MP0003123_paternal_imprinting2.43830517
12MP0010307_abnormal_tumor_latency2.27240324
13MP0000350_abnormal_cell_proliferation2.12448136
14MP0003221_abnormal_cardiomyocyte_apopto2.12123599
15MP0008058_abnormal_DNA_repair2.11105183
16MP0003705_abnormal_hypodermis_morpholog2.02047377
17MP0005380_embryogenesis_phenotype1.97920793
18MP0001672_abnormal_embryogenesis/_devel1.97920793
19MP0008932_abnormal_embryonic_tissue1.89925433
20MP0002088_abnormal_embryonic_growth/wei1.87725427
21MP0003890_abnormal_embryonic-extraembry1.84603677
22MP0003984_embryonic_growth_retardation1.84319340
23MP0008007_abnormal_cellular_replicative1.79287735
24MP0001697_abnormal_embryo_size1.72882634
25MP0009053_abnormal_anal_canal1.70675573
26MP0000537_abnormal_urethra_morphology1.68549106
27MP0002080_prenatal_lethality1.67916274
28MP0003186_abnormal_redox_activity1.67208698
29MP0002086_abnormal_extraembryonic_tissu1.67044222
30MP0003937_abnormal_limbs/digits/tail_de1.56861222
31MP0000358_abnormal_cell_content/1.54885455
32MP0004197_abnormal_fetal_growth/weight/1.54742647
33MP0005076_abnormal_cell_differentiation1.52761030
34MP0003567_abnormal_fetal_cardiomyocyte1.50332339
35MP0001986_abnormal_taste_sensitivity1.47240615
36MP0002084_abnormal_developmental_patter1.45909605
37MP0002254_reproductive_system_inflammat1.39896300
38MP0002085_abnormal_embryonic_tissue1.36679055
39MP0003566_abnormal_cell_adhesion1.36555395
40MP0006035_abnormal_mitochondrial_morpho1.36470295
41MP0002796_impaired_skin_barrier1.35043080
42MP0003941_abnormal_skin_development1.31934879
43MP0009672_abnormal_birth_weight1.30588052
44MP0000750_abnormal_muscle_regeneration1.30102503
45MP0000579_abnormal_nail_morphology1.26577409
46MP0000490_abnormal_crypts_of1.26103951
47MP0006036_abnormal_mitochondrial_physio1.25837134
48MP0004264_abnormal_extraembryonic_tissu1.24591865
49MP0000313_abnormal_cell_death1.24573232
50MP0003786_premature_aging1.23464326
51MP0001661_extended_life_span1.22719807
52MP0001293_anophthalmia1.21931877
53MP0002269_muscular_atrophy1.21056901
54MP0005501_abnormal_skin_physiology1.16422821
55MP0003718_maternal_effect1.13447244
56MP0002019_abnormal_tumor_incidence1.09923221
57MP0009333_abnormal_splenocyte_physiolog1.07968346
58MP0001286_abnormal_eye_development1.06503530
59MP0006292_abnormal_olfactory_placode1.05720333
60MP0002396_abnormal_hematopoietic_system1.04158885
61MP0002938_white_spotting1.04114074
62MP0002697_abnormal_eye_size1.02555065
63MP0003315_abnormal_perineum_morphology1.02362448
64MP0010030_abnormal_orbit_morphology1.01249566
65MP0000733_abnormal_muscle_development1.00681958
66MP0003119_abnormal_digestive_system1.00443595
67MP0002233_abnormal_nose_morphology0.99760603
68MP0005384_cellular_phenotype0.93344836
69MP0005330_cardiomyopathy0.92703334
70MP0005266_abnormal_metabolism0.92263304
71MP0000598_abnormal_liver_morphology0.90192162
72MP0000762_abnormal_tongue_morphology0.90128018
73MP0002139_abnormal_hepatobiliary_system0.89772758
74MP0002111_abnormal_tail_morphology0.89653033
75MP0003950_abnormal_plasma_membrane0.88605612
76MP0000858_altered_metastatic_potential0.87629733
77MP0000747_muscle_weakness0.87407365
78MP0005621_abnormal_cell_physiology0.87375427
79MP0004272_abnormal_basement_membrane0.85665573
80MP0010678_abnormal_skin_adnexa0.85277802
81MP0005187_abnormal_penis_morphology0.84216981
82MP0004808_abnormal_hematopoietic_stem0.82446198
83MP0001529_abnormal_vocalization0.82309510
84MP0005319_abnormal_enzyme/_coenzyme0.81904032
85MP0001299_abnormal_eye_distance/0.80646352
86MP0004084_abnormal_cardiac_muscle0.80067484
87MP0001929_abnormal_gametogenesis0.79835119
88MP0002060_abnormal_skin_morphology0.79635981
89MP0002092_abnormal_eye_morphology0.79122472
90MP0004087_abnormal_muscle_fiber0.79110666
91MP0004233_abnormal_muscle_weight0.78467063
92MP0001756_abnormal_urination0.77428885
93MP0002163_abnormal_gland_morphology0.76444320
94MP0000609_abnormal_liver_physiology0.76435174
95MP0005395_other_phenotype0.76097793
96MP0001853_heart_inflammation0.75675503
97MP0002877_abnormal_melanocyte_morpholog0.75675152
98MP0003303_peritoneal_inflammation0.75125990
99MP0000627_abnormal_mammary_gland0.74857213
100MP0005085_abnormal_gallbladder_physiolo0.73897153
101MP0005023_abnormal_wound_healing0.72989203
102MP0009703_decreased_birth_body0.72988193
103MP0006072_abnormal_retinal_apoptosis0.72801579
104MP0008789_abnormal_olfactory_epithelium0.72792863
105MP0008877_abnormal_DNA_methylation0.72606289
106MP0003755_abnormal_palate_morphology0.71812744
107MP0000371_diluted_coat_color0.71482737
108MP0005367_renal/urinary_system_phenotyp0.70022879
109MP0000516_abnormal_urinary_system0.70022879
110MP0000647_abnormal_sebaceous_gland0.69575452
111MP0000432_abnormal_head_morphology0.69398518
112MP0002006_tumorigenesis0.68175178
113MP0001915_intracranial_hemorrhage0.67985406
114MP0001216_abnormal_epidermal_layer0.67816399
115MP0005408_hypopigmentation0.67637343
116MP0002210_abnormal_sex_determination0.66416183
117MP0000653_abnormal_sex_gland0.66279171
118MP0001881_abnormal_mammary_gland0.65932002
119MP0005332_abnormal_amino_acid0.65335327
120MP0000467_abnormal_esophagus_morphology0.64775751
121MP0002234_abnormal_pharynx_morphology0.64536761
122MP0008770_decreased_survivor_rate0.63920114
123MP0003656_abnormal_erythrocyte_physiolo0.63014840
124MP0000749_muscle_degeneration0.61215878
125MP0004215_abnormal_myocardial_fiber0.61195152
126MP0003943_abnormal_hepatobiliary_system0.60985516
127MP0003828_pulmonary_edema0.60783276
128MP0003436_decreased_susceptibility_to0.60373364
129MP0009643_abnormal_urine_homeostasis0.60310201
130MP0010630_abnormal_cardiac_muscle0.60217725
131MP0006054_spinal_hemorrhage0.59613044
132MP0003121_genomic_imprinting0.59075720
133MP0001145_abnormal_male_reproductive0.58055498
134MP0004782_abnormal_surfactant_physiolog0.58022659
135MP0000477_abnormal_intestine_morphology0.56435547
136MP0002106_abnormal_muscle_physiology0.55891129
137MP0001727_abnormal_embryo_implantation0.53874429
138MP0009697_abnormal_copulation0.53441349
139MP0000266_abnormal_heart_morphology0.53390339

Predicted human phenotypes

RankGene SetZ-score
1Fibular aplasia (HP:0002990)5.91716764
2Chromosomal breakage induced by crosslinking agents (HP:0003221)4.37544005
3Hypoplasia of the capital femoral epiphysis (HP:0003090)4.30835506
4Chromsome breakage (HP:0040012)4.26837777
5Asymmetry of the thorax (HP:0001555)3.81003327
6Abnormality of the anterior horn cell (HP:0006802)3.78384552
7Degeneration of anterior horn cells (HP:0002398)3.78384552
8Birth length less than 3rd percentile (HP:0003561)3.65851481
9Thoracic kyphosis (HP:0002942)3.63919386
10Rough bone trabeculation (HP:0100670)3.40487715
11Natal tooth (HP:0000695)3.36442836
12Nephroblastoma (Wilms tumor) (HP:0002667)3.25050045
13Meckel diverticulum (HP:0002245)3.24662503
14Multiple enchondromatosis (HP:0005701)3.23425939
15Colon cancer (HP:0003003)3.19746340
16Embryonal renal neoplasm (HP:0011794)3.18668821
17Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)3.16986070
18Absent epiphyses (HP:0010577)3.16986070
19Abnormality of the ileum (HP:0001549)3.10820353
20Abnormality of methionine metabolism (HP:0010901)3.10685987
21Abnormality of the preputium (HP:0100587)3.10484017
22Abnormality of chromosome stability (HP:0003220)3.09160245
23Small intestinal stenosis (HP:0012848)2.99910571
24Duodenal stenosis (HP:0100867)2.99910571
25Abnormal lung lobation (HP:0002101)2.93117827
26Selective tooth agenesis (HP:0001592)2.91295682
27Hyperglycinemia (HP:0002154)2.90545050
28Aplasia/hypoplasia of the humerus (HP:0006507)2.89777906
29Aplasia/Hypoplasia of the uvula (HP:0010293)2.89121214
30Wrist flexion contracture (HP:0001239)2.87705526
31Abnormality of the thoracic spine (HP:0100711)2.85059678
32Increased nuchal translucency (HP:0010880)2.80677013
33Focal segmental glomerulosclerosis (HP:0000097)2.75306465
34Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.71024503
35Spinal muscular atrophy (HP:0007269)2.69098632
36Abnormality of the duodenum (HP:0002246)2.61815192
37Short humerus (HP:0005792)2.60160822
38Microvesicular hepatic steatosis (HP:0001414)2.60100850
39Cellular immunodeficiency (HP:0005374)2.58529495
40Pancreatic islet-cell hyperplasia (HP:0004510)2.58168808
41Breast hypoplasia (HP:0003187)2.51300735
42Abnormal trabecular bone morphology (HP:0100671)2.49412016
43Abnormality of aspartate family amino acid metabolism (HP:0010899)2.46630848
44Ependymoma (HP:0002888)2.45812833
45Pelvic girdle muscle weakness (HP:0003749)2.43566337
46High pitched voice (HP:0001620)2.43452600
47Hypoglycemic seizures (HP:0002173)2.41756441
48Increased hepatocellular lipid droplets (HP:0006565)2.39444429
49Personality changes (HP:0000751)2.39357693
50Biliary tract neoplasm (HP:0100574)2.35362584
51Cerebral hypomyelination (HP:0006808)2.33733961
52Neoplasm of the colon (HP:0100273)2.29211157
53Volvulus (HP:0002580)2.28392766
54Glomerulosclerosis (HP:0000096)2.28347664
55Absent radius (HP:0003974)2.28275216
56Shoulder girdle muscle weakness (HP:0003547)2.27582574
57Aplasia/Hypoplasia of the fibula (HP:0006492)2.27163325
58Exercise-induced muscle cramps (HP:0003710)2.26373761
59Partial agenesis of the corpus callosum (HP:0001338)2.26200844
60Adenoma sebaceum (HP:0009720)2.25600839
61Angiofibromas (HP:0010615)2.25600839
62Trismus (HP:0000211)2.21378968
63Abnormality of serum amino acid levels (HP:0003112)2.21127298
64Abnormality of the labia minora (HP:0012880)2.21077948
65Megaloblastic anemia (HP:0001889)2.17695868
66Spastic diplegia (HP:0001264)2.17251238
67Thyroid-stimulating hormone excess (HP:0002925)2.17103839
68Anal stenosis (HP:0002025)2.17086844
69Breast carcinoma (HP:0003002)2.16262834
70Agnosia (HP:0010524)2.15773944
71Sparse eyelashes (HP:0000653)2.14552572
72Neoplasm of the adrenal gland (HP:0100631)2.14357705
73Entropion (HP:0000621)2.11305985
74Glioma (HP:0009733)2.08372628
75Patellar aplasia (HP:0006443)2.05850207
76Abnormal spermatogenesis (HP:0008669)2.05748929
77Oral leukoplakia (HP:0002745)2.03011881
78Aplasia involving forearm bones (HP:0009822)2.02713532
79Absent forearm bone (HP:0003953)2.02713532
80Horseshoe kidney (HP:0000085)2.02270003
81Right ventricular cardiomyopathy (HP:0011663)2.02257252
82Abnormality of the calcaneus (HP:0008364)2.02177514
83Lipid accumulation in hepatocytes (HP:0006561)2.01190702
84Atrophy/Degeneration involving motor neurons (HP:0007373)2.00209851
85Type I transferrin isoform profile (HP:0003642)1.99202673
86Medulloblastoma (HP:0002885)1.98022916
87Osteolytic defects of the hand bones (HP:0009699)1.97004510
88Osteolytic defects of the phalanges of the hand (HP:0009771)1.97004510
89Abnormality of the carotid arteries (HP:0005344)1.96725370
90Microretrognathia (HP:0000308)1.96567649
91Impulsivity (HP:0100710)1.94034081
92Abnormality of the astrocytes (HP:0100707)1.93713087
93Astrocytoma (HP:0009592)1.93713087
94Rimmed vacuoles (HP:0003805)1.93293478
95Microglossia (HP:0000171)1.93180583
96Abnormality of the hip-girdle musculature (HP:0001445)1.92990937
97Abnormality of the musculature of the pelvis (HP:0001469)1.92990937
98Ectopic kidney (HP:0000086)1.91836406
99Ovarian neoplasm (HP:0100615)1.91808940
100Progressive muscle weakness (HP:0003323)1.91033957
101Abnormality of placental membranes (HP:0011409)1.90754054
102Amniotic constriction ring (HP:0009775)1.90754054
103Reduced subcutaneous adipose tissue (HP:0003758)1.90715437
104Increased serum pyruvate (HP:0003542)1.89912959
105Abnormality of glycolysis (HP:0004366)1.89912959
106Cortical dysplasia (HP:0002539)1.89644484
107Stenosis of the external auditory canal (HP:0000402)1.89058494
108Aplasia/Hypoplasia of the patella (HP:0006498)1.89028246
109Embryonal neoplasm (HP:0002898)1.88246270
110Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.88021999
111Abnormal protein N-linked glycosylation (HP:0012347)1.88021999
112Abnormal protein glycosylation (HP:0012346)1.88021999
113Abnormal glycosylation (HP:0012345)1.88021999
114Neoplasm of the adrenal cortex (HP:0100641)1.87165439
115Sloping forehead (HP:0000340)1.87150675
116Triphalangeal thumb (HP:0001199)1.85714835
117Increased serum lactate (HP:0002151)1.85519166
118Long foot (HP:0001833)1.85281424
119Rhabdomyolysis (HP:0003201)1.84975732
120Reticulocytopenia (HP:0001896)1.84339031
121Abnormality of pyrimidine metabolism (HP:0004353)1.84106786
122Abnormality of the pancreatic islet cells (HP:0006476)1.83957958
123Abnormality of endocrine pancreas physiology (HP:0012093)1.83957958
124Facial cleft (HP:0002006)1.83951314
125Choanal atresia (HP:0000453)1.83629213
126Abnormalities of placenta or umbilical cord (HP:0001194)1.83549506
127Nasal speech (HP:0001611)1.83403568
128Autoamputation (HP:0001218)1.83317127
129Cafe-au-lait spot (HP:0000957)1.82401806
130Pterygium (HP:0001059)1.82176692
131Bifid tongue (HP:0010297)1.81933489
132Acute encephalopathy (HP:0006846)1.81891398
133Nuclear cataract (HP:0100018)1.80699145
134Malignant gastrointestinal tract tumors (HP:0006749)1.80276372
135Gastrointestinal carcinoma (HP:0002672)1.80276372
136Reduced antithrombin III activity (HP:0001976)1.80081518
137Carpal bone hypoplasia (HP:0001498)1.79923641
138Palpitations (HP:0001962)1.79915936
139Limb hypertonia (HP:0002509)1.79894819
140Global brain atrophy (HP:0002283)1.77932953
141Symptomatic seizures (HP:0011145)1.77464322
142Proximal placement of thumb (HP:0009623)1.77337284
143Zonular cataract (HP:0010920)1.77000717
144Increased density of long bones (HP:0006392)1.76996662
145Abnormality of sulfur amino acid metabolism (HP:0004339)1.75695593
146Increased connective tissue (HP:0009025)1.75606160
147Deviation of the thumb (HP:0009603)1.74511038
148Abnormal biliary tract morphology (HP:0012440)1.74463057
149Abnormality of the umbilical cord (HP:0010881)1.74269419
150Neoplasm of the pancreas (HP:0002894)1.73638054
151Abnormality of the pons (HP:0007361)1.72102941
152Postnatal microcephaly (HP:0005484)1.71802227
153Uterine neoplasm (HP:0010784)1.71577574
154Abnormality of glycine metabolism (HP:0010895)1.70309811
155Abnormality of serine family amino acid metabolism (HP:0010894)1.70309811
156Thrombocytosis (HP:0001894)1.70196836
157Basal cell carcinoma (HP:0002671)1.69769485
158Areflexia of lower limbs (HP:0002522)1.69503322
159Hypobetalipoproteinemia (HP:0003563)1.69267427
160Prominent metopic ridge (HP:0005487)1.69257615
161Rhabdomyosarcoma (HP:0002859)1.68394026
162Hypoplasia of the pons (HP:0012110)1.67816614
163Hyperinsulinemic hypoglycemia (HP:0000825)1.67684662
164Distal arthrogryposis (HP:0005684)1.67378389
165Fused cervical vertebrae (HP:0002949)1.67273867
166Myelodysplasia (HP:0002863)1.67255409
167Hyperglycinuria (HP:0003108)1.66853697
168Delayed closure of the anterior fontanelle (HP:0001476)1.66546039
169Abnormality of monocarboxylic acid metabolism (HP:0010996)1.66407114
170Squamous cell carcinoma (HP:0002860)1.65539186

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.29057292
2BUB13.98755705
3WEE13.38569782
4BRSK23.23670080
5NEK12.92907230
6SRPK12.62442944
7TAOK22.56876303
8TRIM282.55294834
9MKNK22.44577642
10EIF2AK12.35639193
11VRK22.30942051
12ACVR1B2.21570509
13EPHA22.17999100
14CCNB12.07439800
15RPS6KA42.02538486
16TTK1.97912689
17NME21.88295229
18NEK21.85245680
19TSSK61.81434011
20NUAK11.76504947
21EIF2AK31.72298580
22RPS6KB21.67339458
23PLK41.65520931
24PLK31.61464206
25TTN1.60520417
26TAF11.55577270
27PKN21.51538360
28BRSK11.46501181
29CDK121.46265246
30PDK31.43674365
31PDK41.43674365
32PASK1.41032535
33PLK11.38360228
34AURKB1.38247178
35FLT31.38001049
36MAP3K31.37592454
37MAP3K81.36304069
38DYRK31.35940170
39PAK41.32497742
40BCR1.28077579
41STK161.25610562
42STK101.19061415
43BCKDK1.18485210
44PBK1.17357727
45MAP3K51.15789745
46TNIK1.09489971
47CDK81.09181995
48CHEK11.08008572
49ATR1.06324093
50MST1R1.06214678
51SIK31.05117403
52MAP2K31.03577524
53SMG11.03079077
54SCYL21.01772717
55NEK91.00543725
56TESK11.00542479
57BRD40.99886137
58EPHA30.97931105
59FGFR10.96173009
60STK390.94715373
61BMPR1B0.91973146
62ZAK0.90137035
63CHEK20.88991645
64LATS10.88479238
65LRRK20.86604022
66AURKA0.86393675
67ALK0.85836393
68STK30.84993064
69CDK40.84879603
70CDK70.82706416
71MAP3K110.80607583
72DYRK1B0.79665351
73MARK30.79381361
74TESK20.78388219
75PLK20.78368202
76ERBB40.74348531
77ABL20.73509557
78LATS20.73375906
79PNCK0.72534325
80CSNK1G10.71334535
81MAP4K20.70830675
82PDK20.69829198
83MAP3K140.69092972
84MAP3K100.68378096
85MELK0.68041201
86JAK30.65762834
87NME10.65544894
88STK40.64057130
89CDK20.63727364
90AKT20.63203574
91PIM10.61815575
92TLK10.61071482
93ERBB30.58673965
94STK240.58321487
95ATM0.58077324
96PAK10.57166326
97WNK40.56348024
98CDK60.56137771
99WNK30.55307445
100CSNK2A20.55091770
101PDGFRA0.54228231
102MAPKAPK30.53640850
103MKNK10.53047414
104TGFBR10.49705051
105CSNK1G30.49392711
106MST40.49103645
107MTOR0.48699298
108CSNK2A10.48019584
109MAP3K120.47029985
110CDK10.46643731
111TAOK10.46361449
112PRKCI0.46010196
113LMTK20.45964774
114CAMKK20.45908169
115MET0.45500791
116ZAP700.44747792
117EEF2K0.43365312
118LIMK10.41554571
119PTK60.40818986
120STK38L0.40185962
121CSNK1A1L0.38233375
122IRAK30.37894347
123PRKDC0.36940053
124AKT30.35390322
125OBSCN0.35268117
126DAPK10.35059992
127TRIB30.34905197
128CDK90.33687411
129CSNK1E0.32465309
130MUSK0.31362717
131VRK10.30397744
132EIF2AK20.29749949
133DMPK0.28749974
134FER0.25662577
135OXSR10.24001777
136NLK0.20897725
137NEK60.19971595
138CSNK1G20.19629257
139CLK10.18686778

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.05326740
2One carbon pool by folate_Homo sapiens_hsa006703.39238791
3DNA replication_Homo sapiens_hsa030303.27271919
4Proteasome_Homo sapiens_hsa030503.25031455
5RNA transport_Homo sapiens_hsa030133.23450381
6RNA polymerase_Homo sapiens_hsa030202.83867136
7Mismatch repair_Homo sapiens_hsa034302.69224039
8Spliceosome_Homo sapiens_hsa030402.63944679
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.61696801
10Pyrimidine metabolism_Homo sapiens_hsa002402.12491936
11Cell cycle_Homo sapiens_hsa041102.01049051
12Base excision repair_Homo sapiens_hsa034101.94258412
13Selenocompound metabolism_Homo sapiens_hsa004501.93776009
142-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.84053623
15Nucleotide excision repair_Homo sapiens_hsa034201.81137450
16mRNA surveillance pathway_Homo sapiens_hsa030151.68063184
17Ribosome_Homo sapiens_hsa030101.67493586
18Cysteine and methionine metabolism_Homo sapiens_hsa002701.66552651
19Homologous recombination_Homo sapiens_hsa034401.60619055
20Folate biosynthesis_Homo sapiens_hsa007901.58854450
21Biosynthesis of amino acids_Homo sapiens_hsa012301.55425871
22Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.52620498
23p53 signaling pathway_Homo sapiens_hsa041151.49281184
24Legionellosis_Homo sapiens_hsa051341.41786524
25Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.38702488
26Steroid biosynthesis_Homo sapiens_hsa001001.38387919
27Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.36444136
28Drug metabolism - other enzymes_Homo sapiens_hsa009831.33223868
29RNA degradation_Homo sapiens_hsa030181.31046030
30Carbon metabolism_Homo sapiens_hsa012001.30749468
31Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.27008166
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.23844092
33Epstein-Barr virus infection_Homo sapiens_hsa051691.23433781
34Vitamin B6 metabolism_Homo sapiens_hsa007501.19965834
35Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.19724160
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.14590638
37Pentose phosphate pathway_Homo sapiens_hsa000301.13249178
38Fatty acid elongation_Homo sapiens_hsa000621.11388671
39Systemic lupus erythematosus_Homo sapiens_hsa053221.11097676
40Viral carcinogenesis_Homo sapiens_hsa052031.06791877
41Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.04510849
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.02143302
43Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.99165483
44Fructose and mannose metabolism_Homo sapiens_hsa000510.93793000
45Purine metabolism_Homo sapiens_hsa002300.93181763
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.91528150
47Basal transcription factors_Homo sapiens_hsa030220.91079637
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.89087160
49Non-homologous end-joining_Homo sapiens_hsa034500.84730901
50Sulfur relay system_Homo sapiens_hsa041220.81257437
51Parkinsons disease_Homo sapiens_hsa050120.81030513
52Fanconi anemia pathway_Homo sapiens_hsa034600.78443368
53Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.77870148
54Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.75633208
55Glutathione metabolism_Homo sapiens_hsa004800.75610554
56Sulfur metabolism_Homo sapiens_hsa009200.75062504
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.73349684
58Huntingtons disease_Homo sapiens_hsa050160.72455286
59Cyanoamino acid metabolism_Homo sapiens_hsa004600.70618722
60Herpes simplex infection_Homo sapiens_hsa051680.67994124
61Antigen processing and presentation_Homo sapiens_hsa046120.67583845
62Protein export_Homo sapiens_hsa030600.66473906
63mTOR signaling pathway_Homo sapiens_hsa041500.64217909
64Apoptosis_Homo sapiens_hsa042100.63326920
65Lysine degradation_Homo sapiens_hsa003100.58301557
66Oocyte meiosis_Homo sapiens_hsa041140.58185010
67Galactose metabolism_Homo sapiens_hsa000520.57827865
68Caffeine metabolism_Homo sapiens_hsa002320.57594566
69Small cell lung cancer_Homo sapiens_hsa052220.56732054
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.56625473
71Hippo signaling pathway_Homo sapiens_hsa043900.55485170
72Oxidative phosphorylation_Homo sapiens_hsa001900.52962449
73TGF-beta signaling pathway_Homo sapiens_hsa043500.52505522
74Fatty acid metabolism_Homo sapiens_hsa012120.51663569
75NOD-like receptor signaling pathway_Homo sapiens_hsa046210.50812782
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50511728
77Pyruvate metabolism_Homo sapiens_hsa006200.50424454
78Viral myocarditis_Homo sapiens_hsa054160.50365197
79HTLV-I infection_Homo sapiens_hsa051660.50127382
80Wnt signaling pathway_Homo sapiens_hsa043100.49442986
81Leishmaniasis_Homo sapiens_hsa051400.47500044
82Primary bile acid biosynthesis_Homo sapiens_hsa001200.46596261
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.46484209
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.46214882
85Arginine and proline metabolism_Homo sapiens_hsa003300.45878784
86Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.45597849
87Peroxisome_Homo sapiens_hsa041460.43564916
88Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.43452443
89Thyroid cancer_Homo sapiens_hsa052160.42746971
90Regulation of autophagy_Homo sapiens_hsa041400.42481147
91MicroRNAs in cancer_Homo sapiens_hsa052060.42142807
92Central carbon metabolism in cancer_Homo sapiens_hsa052300.41663307
93Bladder cancer_Homo sapiens_hsa052190.39367803
94Type I diabetes mellitus_Homo sapiens_hsa049400.39295279
95Shigellosis_Homo sapiens_hsa051310.38665638
96Fatty acid degradation_Homo sapiens_hsa000710.38491349
97Adherens junction_Homo sapiens_hsa045200.37454752
98Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.36627527
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.36552752
100Measles_Homo sapiens_hsa051620.36074277
101Arginine biosynthesis_Homo sapiens_hsa002200.35723053
102HIF-1 signaling pathway_Homo sapiens_hsa040660.33523125
103Influenza A_Homo sapiens_hsa051640.32696017
104N-Glycan biosynthesis_Homo sapiens_hsa005100.32123294
105Maturity onset diabetes of the young_Homo sapiens_hsa049500.28337611
106Colorectal cancer_Homo sapiens_hsa052100.27262075
107Metabolic pathways_Homo sapiens_hsa011000.26826519
108Tight junction_Homo sapiens_hsa045300.25965086
109Alzheimers disease_Homo sapiens_hsa050100.25909565
110Propanoate metabolism_Homo sapiens_hsa006400.25472032
111Basal cell carcinoma_Homo sapiens_hsa052170.25053844
112Fat digestion and absorption_Homo sapiens_hsa049750.23385565
113Pentose and glucuronate interconversions_Homo sapiens_hsa000400.23065154
114Allograft rejection_Homo sapiens_hsa053300.22137790
115Chronic myeloid leukemia_Homo sapiens_hsa052200.21863189
116Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.21513630
117Butanoate metabolism_Homo sapiens_hsa006500.21151373
118Vitamin digestion and absorption_Homo sapiens_hsa049770.17994214
119Hedgehog signaling pathway_Homo sapiens_hsa043400.17202587
120Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.15287082
121Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.15274468
122Prostate cancer_Homo sapiens_hsa052150.14519902
123beta-Alanine metabolism_Homo sapiens_hsa004100.14038078
124Starch and sucrose metabolism_Homo sapiens_hsa005000.13550039
125Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.10815895

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