METTL10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)4.31694035
2termination of RNA polymerase III transcription (GO:0006386)3.98501240
3transcription elongation from RNA polymerase III promoter (GO:0006385)3.98501240
4DNA double-strand break processing (GO:0000729)3.93652295
5histone exchange (GO:0043486)3.92351750
6cullin deneddylation (GO:0010388)3.88744686
7protein complex biogenesis (GO:0070271)3.86321972
87-methylguanosine mRNA capping (GO:0006370)3.82200630
9RNA capping (GO:0036260)3.81534867
107-methylguanosine RNA capping (GO:0009452)3.81534867
11mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.73120861
12mitochondrial respiratory chain complex I assembly (GO:0032981)3.73120861
13NADH dehydrogenase complex assembly (GO:0010257)3.73120861
14respiratory chain complex IV assembly (GO:0008535)3.69401865
15GTP biosynthetic process (GO:0006183)3.66609844
16kinetochore organization (GO:0051383)3.65072120
17protein deneddylation (GO:0000338)3.59403995
18establishment of protein localization to mitochondrial membrane (GO:0090151)3.59127199
19ribosomal small subunit assembly (GO:0000028)3.54443324
20attachment of spindle microtubules to kinetochore (GO:0008608)3.52914957
21tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.52562375
22RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.52562375
23DNA replication-independent nucleosome organization (GO:0034724)3.50903138
24DNA replication-independent nucleosome assembly (GO:0006336)3.50903138
25guanosine-containing compound biosynthetic process (GO:1901070)3.48944747
26termination of RNA polymerase I transcription (GO:0006363)3.48350530
27transcription elongation from RNA polymerase I promoter (GO:0006362)3.48094183
28mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.46587912
29regulation of mitochondrial translation (GO:0070129)3.45732629
30establishment of integrated proviral latency (GO:0075713)3.45340728
31regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.45022753
32regulation of mitotic spindle checkpoint (GO:1903504)3.45022753
33regulation of centriole replication (GO:0046599)3.43849100
34mitotic metaphase plate congression (GO:0007080)3.43789624
35negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.43449692
36rRNA modification (GO:0000154)3.42395257
37mitochondrial respiratory chain complex assembly (GO:0033108)3.41976783
38ATP synthesis coupled proton transport (GO:0015986)3.40194037
39energy coupled proton transport, down electrochemical gradient (GO:0015985)3.40194037
40DNA damage response, detection of DNA damage (GO:0042769)3.39650112
41protein localization to kinetochore (GO:0034501)3.35848334
42mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.35799982
43cytochrome complex assembly (GO:0017004)3.35612783
44replication fork processing (GO:0031297)3.35564623
45DNA deamination (GO:0045006)3.35536210
46spindle checkpoint (GO:0031577)3.32115928
47L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.31809472
48mitotic spindle checkpoint (GO:0071174)3.30989949
49negative regulation of DNA-dependent DNA replication (GO:2000104)3.30714512
50maturation of 5.8S rRNA (GO:0000460)3.29154679
51ribosomal small subunit biogenesis (GO:0042274)3.27659288
52centriole replication (GO:0007099)3.25411416
53metaphase plate congression (GO:0051310)3.23287936
54negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.22353594
55negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.22353594
56negative regulation of mitotic sister chromatid segregation (GO:0033048)3.22353594
57negative regulation of mitotic sister chromatid separation (GO:2000816)3.22353594
58negative regulation of sister chromatid segregation (GO:0033046)3.22353594
59histone mRNA metabolic process (GO:0008334)3.22105446
60peptidyl-histidine modification (GO:0018202)3.21332221
61positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.20793586
62intraciliary transport (GO:0042073)3.17897656
63protein K6-linked ubiquitination (GO:0085020)3.16873263
64rRNA methylation (GO:0031167)3.15131371
65deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.14884141
66protein neddylation (GO:0045116)3.14345301
67sister chromatid segregation (GO:0000819)3.13785888
68mitotic sister chromatid segregation (GO:0000070)3.13700796
69microtubule depolymerization (GO:0007019)3.13261054
70chaperone-mediated protein transport (GO:0072321)3.12568152
71mitotic spindle assembly checkpoint (GO:0007094)3.12387349
72regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.11373364
73negative regulation of chromosome segregation (GO:0051985)3.11041272
74DNA replication-dependent nucleosome assembly (GO:0006335)3.10922189
75DNA replication-dependent nucleosome organization (GO:0034723)3.10922189
76signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.10619088
77signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.10619088
78signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.10619088
79establishment of viral latency (GO:0019043)3.09317680
80viral mRNA export from host cell nucleus (GO:0046784)3.07651470
81spindle assembly checkpoint (GO:0071173)3.07623044
82DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.07474353
83negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.05929362
84negative regulation of ligase activity (GO:0051352)3.05929362
85tRNA methylation (GO:0030488)3.03728306
86exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.03602692
87RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.02753485
88intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.02677463
89signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.02677463
90resolution of meiotic recombination intermediates (GO:0000712)3.02151233
91transcription-coupled nucleotide-excision repair (GO:0006283)3.02104549
92nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.01925764
93UTP biosynthetic process (GO:0006228)3.01169571
94CENP-A containing nucleosome assembly (GO:0034080)3.00229183
95regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.00036083
96signal transduction involved in cell cycle checkpoint (GO:0072395)2.99608087
97organelle disassembly (GO:1903008)2.97290156
98transcription from RNA polymerase I promoter (GO:0006360)2.96866793
99regulation of cellular amino acid metabolic process (GO:0006521)2.96163646
100signal transduction involved in DNA damage checkpoint (GO:0072422)2.95372007
101signal transduction involved in DNA integrity checkpoint (GO:0072401)2.95372007
102ribonucleoprotein complex disassembly (GO:0032988)2.95005531
103anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.94849294
104spliceosomal complex assembly (GO:0000245)2.94121651
105regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.93334085
106regulation of mitotic metaphase/anaphase transition (GO:0030071)2.93334085
107maturation of SSU-rRNA (GO:0030490)2.90696639
108ribosome assembly (GO:0042255)2.90480478
109deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.89477708
110deoxyribonucleoside diphosphate metabolic process (GO:0009186)2.89032005
111regulation of sister chromatid segregation (GO:0033045)2.88357737
112regulation of mitotic sister chromatid separation (GO:0010965)2.88357737
113regulation of mitotic sister chromatid segregation (GO:0033047)2.88357737
114non-recombinational repair (GO:0000726)2.86945176
115double-strand break repair via nonhomologous end joining (GO:0006303)2.86945176
116synapsis (GO:0007129)2.86518227
117regulation of DNA endoreduplication (GO:0032875)2.85964390
118mannosylation (GO:0097502)2.85783052
119recombinational repair (GO:0000725)2.85692793
120deoxyribonucleotide biosynthetic process (GO:0009263)2.85169282
121protein K11-linked ubiquitination (GO:0070979)2.83740482
122purine nucleobase biosynthetic process (GO:0009113)2.83730351
123histone H2A acetylation (GO:0043968)2.83678318
124CTP biosynthetic process (GO:0006241)2.80993712
125CTP metabolic process (GO:0046036)2.80993712
126protein localization to chromosome, centromeric region (GO:0071459)2.78901188
127double-strand break repair via homologous recombination (GO:0000724)2.78806274
128maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.78718932
129preassembly of GPI anchor in ER membrane (GO:0016254)2.78656037
130telomere maintenance via semi-conservative replication (GO:0032201)2.78508929
131pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.77797212
132deoxyribose phosphate biosynthetic process (GO:0046385)2.77521301
1332-deoxyribonucleotide biosynthetic process (GO:0009265)2.77521301
134transcription initiation from RNA polymerase I promoter (GO:0006361)2.77213474
135chromatin remodeling at centromere (GO:0031055)2.76665297
136cellular component biogenesis (GO:0044085)2.76505610
137regulation of helicase activity (GO:0051095)2.75459228
138tRNA processing (GO:0008033)2.73190711
139antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.72852511
140transcription elongation from RNA polymerase II promoter (GO:0006368)2.72595552
141spliceosomal snRNP assembly (GO:0000387)2.72402544
142DNA replication checkpoint (GO:0000076)2.71637909
143positive regulation of ligase activity (GO:0051351)2.71107927
144DNA-templated transcription, elongation (GO:0006354)2.70991010
145ribonucleoprotein complex biogenesis (GO:0022613)2.70294760
146pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.69118279
147kinetochore assembly (GO:0051382)2.68991145
148DNA ligation (GO:0006266)2.66875385
149positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.66779749
150regulation of chromosome segregation (GO:0051983)2.66326461
151protein-cofactor linkage (GO:0018065)2.66132042
152GPI anchor biosynthetic process (GO:0006506)2.65717416
153pseudouridine synthesis (GO:0001522)2.65675446
154cotranslational protein targeting to membrane (GO:0006613)2.65585785
155translation (GO:0006412)2.64879361
156SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.64266533
157ribosomal large subunit biogenesis (GO:0042273)2.63735267
158regulation of nuclear cell cycle DNA replication (GO:0033262)2.62778768
159positive regulation of protein homodimerization activity (GO:0090073)2.62630485
160RNA methylation (GO:0001510)2.62512867
161DNA catabolic process, exonucleolytic (GO:0000738)2.58622852

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.34769386
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.80260302
3EST1_17652178_ChIP-ChIP_JURKAT_Human3.66052865
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.28323018
5HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.09641640
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.09347728
7* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.03116018
8E2F7_22180533_ChIP-Seq_HELA_Human2.85257071
9CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.82380816
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.72067048
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.70814110
12ELF1_17652178_ChIP-ChIP_JURKAT_Human2.58504139
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.48370039
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.45531065
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.45084436
16ELK1_19687146_ChIP-ChIP_HELA_Human2.38493252
17FOXM1_23109430_ChIP-Seq_U2OS_Human2.36085881
18E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.34353033
19VDR_23849224_ChIP-Seq_CD4+_Human2.34067355
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.27142718
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.21056041
22SRF_21415370_ChIP-Seq_HL-1_Mouse2.16524547
23E2F4_17652178_ChIP-ChIP_JURKAT_Human2.14266851
24ZNF274_21170338_ChIP-Seq_K562_Hela2.12896111
25FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.05859301
26PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.03792751
27TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.03244554
28MYC_18358816_ChIP-ChIP_MESCs_Mouse1.95827553
29SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.94416164
30MYC_19030024_ChIP-ChIP_MESCs_Mouse1.93761204
31IRF1_19129219_ChIP-ChIP_H3396_Human1.93368615
32FOXP3_21729870_ChIP-Seq_TREG_Human1.92095811
33THAP11_20581084_ChIP-Seq_MESCs_Mouse1.91632815
34KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.83749551
35MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.82940733
36YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.82204643
37FUS_26573619_Chip-Seq_HEK293_Human1.80676316
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.77981887
39FLI1_27457419_Chip-Seq_LIVER_Mouse1.75668364
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.72262480
41DCP1A_22483619_ChIP-Seq_HELA_Human1.71855719
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.68880351
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.68094785
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.64963963
45TTF2_22483619_ChIP-Seq_HELA_Human1.64851363
46MYC_19079543_ChIP-ChIP_MESCs_Mouse1.63204112
47TP63_19390658_ChIP-ChIP_HaCaT_Human1.60203302
48E2F1_18555785_ChIP-Seq_MESCs_Mouse1.59997643
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.57779743
50MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.57148231
51PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56783168
52IGF1R_20145208_ChIP-Seq_DFB_Human1.56628806
53NELFA_20434984_ChIP-Seq_ESCs_Mouse1.54084094
54* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.54024825
55EZH2_22144423_ChIP-Seq_EOC_Human1.53183486
56BMI1_23680149_ChIP-Seq_NPCS_Mouse1.51736227
57XRN2_22483619_ChIP-Seq_HELA_Human1.51242592
58POU3F2_20337985_ChIP-ChIP_501MEL_Human1.51171743
59VDR_22108803_ChIP-Seq_LS180_Human1.50676601
60TAF15_26573619_Chip-Seq_HEK293_Human1.50506582
61POU5F1_16153702_ChIP-ChIP_HESCs_Human1.41757805
62EWS_26573619_Chip-Seq_HEK293_Human1.39864360
63GBX2_23144817_ChIP-Seq_PC3_Human1.39300998
64E2F1_21310950_ChIP-Seq_MCF-7_Human1.39113577
65PADI4_21655091_ChIP-ChIP_MCF-7_Human1.38268628
66GABP_19822575_ChIP-Seq_HepG2_Human1.36203625
67CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.35125812
68FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.25317042
69* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.23589561
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.20957053
71ELK1_22589737_ChIP-Seq_MCF10A_Human1.20875321
72EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.20754170
73CTBP2_25329375_ChIP-Seq_LNCAP_Human1.20427558
74AR_21909140_ChIP-Seq_LNCAP_Human1.20421968
75SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.20202807
76IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.18265355
77CBP_20019798_ChIP-Seq_JUKART_Human1.18265355
78MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15743020
79SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12835199
80NFE2_27457419_Chip-Seq_LIVER_Mouse1.11450339
81MYC_18940864_ChIP-ChIP_HL60_Human1.10550476
82TP53_22573176_ChIP-Seq_HFKS_Human1.09552035
83UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09523954
84AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.09154792
85MYCN_18555785_ChIP-Seq_MESCs_Mouse1.08674811
86POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.08231921
87CBX2_27304074_Chip-Seq_ESCs_Mouse1.07856625
88CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07170217
89MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06984025
90SOX2_18555785_ChIP-Seq_MESCs_Mouse1.05487693
91ERG_20887958_ChIP-Seq_HPC-7_Mouse1.05009422
92RNF2_27304074_Chip-Seq_NSC_Mouse1.02505169
93SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02161896
94FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.01803731
95HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.01499987
96NANOG_16153702_ChIP-ChIP_HESCs_Human1.00705319
97GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.00153512
98SALL1_21062744_ChIP-ChIP_HESCs_Human1.00041446
99EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.97546195
100NANOG_19829295_ChIP-Seq_ESCs_Human0.97402625
101SOX2_19829295_ChIP-Seq_ESCs_Human0.97402625
102DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96579810
103CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.96524176
104GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96497337
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.96067018
106P300_19829295_ChIP-Seq_ESCs_Human0.96050864
107GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95915150
108IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.95106866
109* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95033629
110PCGF2_27294783_Chip-Seq_NPCs_Mouse0.94306926
111KLF5_20875108_ChIP-Seq_MESCs_Mouse0.93038533
112OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.92626900
113ER_23166858_ChIP-Seq_MCF-7_Human0.92598127
114PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.91721534
115NANOG_18555785_Chip-Seq_ESCs_Mouse0.91297978
116EZH2_27294783_Chip-Seq_NPCs_Mouse0.90785266
117TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.90721411
118NANOG_18555785_ChIP-Seq_MESCs_Mouse0.89950074
119CIITA_25753668_ChIP-Seq_RAJI_Human0.89620094
120SOX2_16153702_ChIP-ChIP_HESCs_Human0.89159841
121P53_22387025_ChIP-Seq_ESCs_Mouse0.88079216
122STAT3_18555785_Chip-Seq_ESCs_Mouse0.87751672
123CRX_20693478_ChIP-Seq_RETINA_Mouse0.87002917
124EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.86840535
125CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.86188635
126RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.84926590
127SUZ12_18555785_Chip-Seq_ESCs_Mouse0.84784862

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001188_hyperpigmentation3.23713501
2MP0006292_abnormal_olfactory_placode3.09264872
3MP0008058_abnormal_DNA_repair2.88104588
4MP0009379_abnormal_foot_pigmentation2.72946389
5MP0001986_abnormal_taste_sensitivity2.36506176
6MP0001529_abnormal_vocalization2.31446699
7MP0008057_abnormal_DNA_replication2.30947201
8MP0002163_abnormal_gland_morphology2.30102123
9MP0003880_abnormal_central_pattern2.25331945
10MP0003693_abnormal_embryo_hatching2.24687615
11MP0005409_darkened_coat_color2.10974612
12MP0003787_abnormal_imprinting2.09946793
13MP0005379_endocrine/exocrine_gland_phen2.02248460
14MP0010094_abnormal_chromosome_stability1.96794510
15MP0008789_abnormal_olfactory_epithelium1.95439509
16MP0000569_abnormal_digit_pigmentation1.94322973
17MP0009697_abnormal_copulation1.87115931
18MP0000566_synostosis1.86379940
19MP0001905_abnormal_dopamine_level1.85848220
20MP0008877_abnormal_DNA_methylation1.83743988
21MP0002277_abnormal_respiratory_mucosa1.83615216
22MP0005645_abnormal_hypothalamus_physiol1.81857846
23MP0008007_abnormal_cellular_replicative1.78771356
24MP0001293_anophthalmia1.77007315
25MP0001984_abnormal_olfaction1.76194179
26MP0002638_abnormal_pupillary_reflex1.75092495
27MP0005646_abnormal_pituitary_gland1.73201333
28MP0000015_abnormal_ear_pigmentation1.69764322
29MP0010386_abnormal_urinary_bladder1.69417231
30MP0004957_abnormal_blastocyst_morpholog1.64974373
31MP0003718_maternal_effect1.64120368
32MP0003111_abnormal_nucleus_morphology1.63214119
33MP0003121_genomic_imprinting1.63023306
34MP0003077_abnormal_cell_cycle1.60156550
35MP0006276_abnormal_autonomic_nervous1.58797365
36MP0005084_abnormal_gallbladder_morpholo1.57293012
37MP0003786_premature_aging1.56342787
38MP0003941_abnormal_skin_development1.54082996
39MP0005423_abnormal_somatic_nervous1.52995158
40MP0005499_abnormal_olfactory_system1.52843680
41MP0005394_taste/olfaction_phenotype1.52843680
42MP0002102_abnormal_ear_morphology1.51586573
43MP0003567_abnormal_fetal_cardiomyocyte1.50195704
44MP0006054_spinal_hemorrhage1.46527276
45MP0000647_abnormal_sebaceous_gland1.43470131
46MP0006072_abnormal_retinal_apoptosis1.41573154
47MP0000427_abnormal_hair_cycle1.39237861
48MP0001764_abnormal_homeostasis1.39041678
49MP0002132_abnormal_respiratory_system1.35662660
50MP0002938_white_spotting1.35269386
51MP0008995_early_reproductive_senescence1.34862900
52MP0006036_abnormal_mitochondrial_physio1.34503383
53MP0000631_abnormal_neuroendocrine_gland1.33569535
54MP0002876_abnormal_thyroid_physiology1.31099565
55MP0003315_abnormal_perineum_morphology1.28252068
56MP0002751_abnormal_autonomic_nervous1.26600049
57MP0003186_abnormal_redox_activity1.23138050
58MP0002090_abnormal_vision1.22743153
59MP0003937_abnormal_limbs/digits/tail_de1.21936874
60MP0008932_abnormal_embryonic_tissue1.21143943
61MP0000372_irregular_coat_pigmentation1.21058618
62MP0000049_abnormal_middle_ear1.19647065
63MP0003122_maternal_imprinting1.19218811
64MP0002160_abnormal_reproductive_system1.17852075
65MP0005171_absent_coat_pigmentation1.17850187
66MP0002095_abnormal_skin_pigmentation1.16723636
67MP0004133_heterotaxia1.16629134
68MP0003136_yellow_coat_color1.13601739
69MP0003221_abnormal_cardiomyocyte_apopto1.11418635
70MP0000681_abnormal_thyroid_gland1.08812128
71MP0005391_vision/eye_phenotype1.07296501
72MP0005389_reproductive_system_phenotype1.05278215
73MP0002837_dystrophic_cardiac_calcinosis1.04039630
74MP0001919_abnormal_reproductive_system1.02798211
75MP0004147_increased_porphyrin_level1.01286334
76MP0003806_abnormal_nucleotide_metabolis1.01138998
77MP0001968_abnormal_touch/_nociception1.00918458
78MP0001697_abnormal_embryo_size0.98731019
79MP0003763_abnormal_thymus_physiology0.97946357
80MP0004215_abnormal_myocardial_fiber0.97413391
81MP0002234_abnormal_pharynx_morphology0.96722084
82MP0005174_abnormal_tail_pigmentation0.96616723
83MP0004142_abnormal_muscle_tone0.96485130
84MP0002557_abnormal_social/conspecific_i0.96348734
85MP0002736_abnormal_nociception_after0.95453086
86MP0000653_abnormal_sex_gland0.93772833
87MP0000026_abnormal_inner_ear0.92593945
88MP0003123_paternal_imprinting0.91695473
89MP0002184_abnormal_innervation0.91683690
90MP0002177_abnormal_outer_ear0.91094927
91MP0000358_abnormal_cell_content/0.90813751
92MP0002210_abnormal_sex_determination0.89783610
93MP0002734_abnormal_mechanical_nocicepti0.89584419
94MP0000350_abnormal_cell_proliferation0.88756306
95MP0002084_abnormal_developmental_patter0.88086878
96MP0009046_muscle_twitch0.86278127
97MP0002572_abnormal_emotion/affect_behav0.85738592
98MP0003938_abnormal_ear_development0.85585182
99MP0001346_abnormal_lacrimal_gland0.83729180
100MP0000678_abnormal_parathyroid_gland0.82796087
101MP0005671_abnormal_response_to0.82226480
102MP0003890_abnormal_embryonic-extraembry0.82220919
103MP0002233_abnormal_nose_morphology0.81845575
104MP0003698_abnormal_male_reproductive0.81666899
105MP0002009_preneoplasia0.81145582
106MP0005253_abnormal_eye_physiology0.80923839
107MP0001730_embryonic_growth_arrest0.80648913
108MP0001286_abnormal_eye_development0.80119906
109MP0005503_abnormal_tendon_morphology0.78494378
110MP0002272_abnormal_nervous_system0.78251485
111MP0001324_abnormal_eye_pigmentation0.78106126
112MP0002085_abnormal_embryonic_tissue0.77078035
113MP0005075_abnormal_melanosome_morpholog0.76551876
114MP0005187_abnormal_penis_morphology0.76348043
115MP0008260_abnormal_autophagy0.76182233
116MP0001963_abnormal_hearing_physiology0.75640515
117MP0009745_abnormal_behavioral_response0.75338342
118MP0003195_calcinosis0.74256674
119MP0002067_abnormal_sensory_capabilities0.74185168
120MP0001119_abnormal_female_reproductive0.73892563
121MP0001672_abnormal_embryogenesis/_devel0.73600898
122MP0005380_embryogenesis_phenotype0.73600898
123MP0001486_abnormal_startle_reflex0.73384040
124MP0005551_abnormal_eye_electrophysiolog0.73359864
125MP0000778_abnormal_nervous_system0.73210964
126MP0005195_abnormal_posterior_eye0.73014308
127MP0002396_abnormal_hematopoietic_system0.70215816
128MP0004742_abnormal_vestibular_system0.69800019
129MP0003183_abnormal_peptide_metabolism0.68706103
130MP0001145_abnormal_male_reproductive0.68695146
131MP0006035_abnormal_mitochondrial_morpho0.67877519
132MP0001186_pigmentation_phenotype0.67483928
133MP0002697_abnormal_eye_size0.67467830
134MP0001929_abnormal_gametogenesis0.65713028
135MP0002752_abnormal_somatic_nervous0.65422782
136MP0002080_prenatal_lethality0.64530688
137MP0005408_hypopigmentation0.64471565
138MP0005248_abnormal_Harderian_gland0.61113096

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.04639524
2Volvulus (HP:0002580)3.76936410
3Abnormal mitochondria in muscle tissue (HP:0008316)3.57017137
4Mitochondrial inheritance (HP:0001427)3.56079467
5Progressive macrocephaly (HP:0004481)3.33958476
63-Methylglutaconic aciduria (HP:0003535)3.32047830
7True hermaphroditism (HP:0010459)3.25537543
8Pancreatic fibrosis (HP:0100732)3.21149010
9Medial flaring of the eyebrow (HP:0010747)3.17977459
10Increased CSF lactate (HP:0002490)3.13672589
11Type I transferrin isoform profile (HP:0003642)3.06574619
12Birth length less than 3rd percentile (HP:0003561)3.04207165
13Hypothermia (HP:0002045)3.03235889
14Hepatocellular necrosis (HP:0001404)3.00170210
15Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.99584401
16Nephrogenic diabetes insipidus (HP:0009806)2.98084491
17Increased hepatocellular lipid droplets (HP:0006565)2.96209788
18Pancreatic cysts (HP:0001737)2.94158425
19Microvesicular hepatic steatosis (HP:0001414)2.93224689
20Congenital primary aphakia (HP:0007707)2.89888063
21Aplastic anemia (HP:0001915)2.86881489
22Gait imbalance (HP:0002141)2.85896164
23Chromosomal breakage induced by crosslinking agents (HP:0003221)2.83031828
24Supernumerary spleens (HP:0009799)2.77744615
25Acute encephalopathy (HP:0006846)2.72899664
26Abnormality of chromosome stability (HP:0003220)2.71911312
27Colon cancer (HP:0003003)2.69022723
28Renal cortical cysts (HP:0000803)2.67746398
29Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.67366669
30Chromsome breakage (HP:0040012)2.67220275
31Abnormality of the labia minora (HP:0012880)2.64961771
32Abnormal hair whorl (HP:0010721)2.64498860
33Cerebral edema (HP:0002181)2.60508597
34Renal Fanconi syndrome (HP:0001994)2.53423586
35Reticulocytopenia (HP:0001896)2.46788698
36Methylmalonic acidemia (HP:0002912)2.41498977
37Exercise intolerance (HP:0003546)2.39300501
38Aplasia/Hypoplasia of the tongue (HP:0010295)2.38162526
39Lipid accumulation in hepatocytes (HP:0006561)2.37921037
40Optic disc pallor (HP:0000543)2.35598092
41Abnormality of midbrain morphology (HP:0002418)2.35253008
42Molar tooth sign on MRI (HP:0002419)2.35253008
43Hepatic necrosis (HP:0002605)2.32035420
44Increased serum lactate (HP:0002151)2.30520819
45Poor coordination (HP:0002370)2.27819043
46Abnormal respiratory epithelium morphology (HP:0012253)2.24320431
47Abnormal respiratory motile cilium morphology (HP:0005938)2.24320431
48Median cleft lip (HP:0000161)2.21743075
49Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.21612142
50Decreased activity of mitochondrial respiratory chain (HP:0008972)2.21612142
51Abnormality of methionine metabolism (HP:0010901)2.21564219
52Abnormality of alanine metabolism (HP:0010916)2.20801993
53Hyperalaninemia (HP:0003348)2.20801993
54Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.20801993
55Abnormality of the renal collecting system (HP:0004742)2.20584998
5611 pairs of ribs (HP:0000878)2.17844750
57Sloping forehead (HP:0000340)2.15788710
58Sclerocornea (HP:0000647)2.13362033
59Preaxial hand polydactyly (HP:0001177)2.12398646
60Bile duct proliferation (HP:0001408)2.10382259
61Abnormal biliary tract physiology (HP:0012439)2.10382259
62Small intestinal stenosis (HP:0012848)2.09834853
63Duodenal stenosis (HP:0100867)2.09834853
64Abnormality of the renal cortex (HP:0011035)2.09578760
65Type 2 muscle fiber atrophy (HP:0003554)2.09243575
66Breast hypoplasia (HP:0003187)2.08951292
67Abnormal ciliary motility (HP:0012262)2.08275332
68Vaginal atresia (HP:0000148)2.07257969
69Abnormality of serum amino acid levels (HP:0003112)2.06441509
70Abnormality of cells of the erythroid lineage (HP:0012130)2.06111289
71Genital tract atresia (HP:0001827)2.05190945
72Hyperglycinemia (HP:0002154)2.04802776
73Abnormality of aspartate family amino acid metabolism (HP:0010899)2.04618370
74Abnormal glycosylation (HP:0012345)2.02057163
75Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.02057163
76Abnormal protein N-linked glycosylation (HP:0012347)2.02057163
77Abnormal protein glycosylation (HP:0012346)2.02057163
78Abnormality of the preputium (HP:0100587)2.01546427
79Meckel diverticulum (HP:0002245)2.01213395
80Aplasia/Hypoplasia of the tibia (HP:0005772)2.00039869
81Abnormal number of erythroid precursors (HP:0012131)1.99782625
82Duplicated collecting system (HP:0000081)1.99462744
83Exertional dyspnea (HP:0002875)1.98016677
84Facial cleft (HP:0002006)1.96330097
85Abnormal respiratory motile cilium physiology (HP:0012261)1.96070881
86Embryonal renal neoplasm (HP:0011794)1.95039804
87Congenital, generalized hypertrichosis (HP:0004540)1.94366516
88Abnormality of secondary sexual hair (HP:0009888)1.94212377
89Abnormality of the axillary hair (HP:0100134)1.94212377
90Abnormality of the ileum (HP:0001549)1.92573008
91Aplasia/Hypoplasia of the lens (HP:0008063)1.92472754
92Respiratory difficulties (HP:0002880)1.92398364
93Abnormality of the duodenum (HP:0002246)1.87878340
94Abnormality of the renal medulla (HP:0100957)1.87335788
95Oral leukoplakia (HP:0002745)1.85846131
96Increased intramyocellular lipid droplets (HP:0012240)1.85703177
97Optic nerve coloboma (HP:0000588)1.85611289
98Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.84826237
99Aplasia/hypoplasia of the uterus (HP:0008684)1.84169584
100Lactic acidosis (HP:0003128)1.83227678
101Abnormality of renal resorption (HP:0011038)1.82758323
102Cortical dysplasia (HP:0002539)1.82710593
103Rough bone trabeculation (HP:0100670)1.82542124
104Methylmalonic aciduria (HP:0012120)1.81883242
105Limb dystonia (HP:0002451)1.81473761
106Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.81047673
107Dandy-Walker malformation (HP:0001305)1.80972892
108Bifid tongue (HP:0010297)1.80972452
109Broad foot (HP:0001769)1.80924439
110Oculomotor apraxia (HP:0000657)1.80580793
111Aplasia/Hypoplasia of the uvula (HP:0010293)1.80524600
112Cystic liver disease (HP:0006706)1.80041702
113Central scotoma (HP:0000603)1.79848949
114Patellar aplasia (HP:0006443)1.79115725
115Aganglionic megacolon (HP:0002251)1.78853850
116Reduced antithrombin III activity (HP:0001976)1.78592568
117Nephronophthisis (HP:0000090)1.76462382
118Small hand (HP:0200055)1.76254795
119Anencephaly (HP:0002323)1.75787897
120Astigmatism (HP:0000483)1.75058430
121Male pseudohermaphroditism (HP:0000037)1.74744788
122Bone marrow hypocellularity (HP:0005528)1.74698171
123Gonadotropin excess (HP:0000837)1.74664570
124Septo-optic dysplasia (HP:0100842)1.74226282
125Abnormal lung lobation (HP:0002101)1.74152196
126Aplasia/Hypoplasia of the sacrum (HP:0008517)1.74124375
127Short tibia (HP:0005736)1.73276185
128Tubulointerstitial nephritis (HP:0001970)1.72894962
129Muscle fiber atrophy (HP:0100295)1.72046754
130Nephroblastoma (Wilms tumor) (HP:0002667)1.72029153
131Narrow forehead (HP:0000341)1.71798070
132Myelodysplasia (HP:0002863)1.71724338
133Lethargy (HP:0001254)1.71239913
134Postaxial foot polydactyly (HP:0001830)1.70653328
135Intestinal atresia (HP:0011100)1.70645280
136Aplasia/Hypoplasia of the patella (HP:0006498)1.70511286
137Progressive inability to walk (HP:0002505)1.68505532
138Progressive external ophthalmoplegia (HP:0000590)1.66858023
139Chronic hepatic failure (HP:0100626)1.66818067
140Adrenal hypoplasia (HP:0000835)1.66571590
141Congenital stationary night blindness (HP:0007642)1.66395263
142Leukodystrophy (HP:0002415)1.65897166
143Pancytopenia (HP:0001876)1.65146368
144Respiratory failure (HP:0002878)1.63612651
145Pallor (HP:0000980)1.61855318

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NEK14.75579212
2STK163.96600319
3MAP4K23.19075469
4CASK3.18504601
5BUB13.15932793
6SRPK12.76049694
7MAP3K122.68798036
8TRIM282.67856239
9VRK12.55003291
10PLK42.28739218
11ADRBK22.18827440
12ZAK2.17567105
13BMPR1B2.15154542
14FRK2.07831612
15MKNK12.07019627
16MAP2K72.05464485
17MKNK21.88765505
18ERBB31.81444314
19EIF2AK31.75833349
20IRAK31.74635663
21CCNB11.74611008
22NEK21.70183462
23MAP3K41.67024858
24TNIK1.63532633
25EIF2AK11.61244558
26IRAK41.58370065
27WEE11.54348664
28PLK31.52870791
29YES11.48887830
30SIK31.48739870
31TXK1.48115386
32MARK11.47610447
33MUSK1.47482189
34TSSK61.47125935
35BMPR21.39735326
36NME11.36073921
37GRK71.34806878
38DYRK31.33389242
39MAPK131.23598944
40CSNK1G21.22115910
41CSNK1G11.16527796
42DYRK21.15893661
43EIF2AK21.15271869
44ACVR1B1.13953322
45BCKDK1.10122912
46MST41.09272989
47BCR1.09221125
48BRSK21.08677675
49CDK31.08343980
50PLK21.07490979
51VRK21.06236916
52BRD41.05991142
53GRK11.05955583
54CSNK1A1L1.05435226
55TEC1.00026637
56AKT30.96286381
57CDC70.95907108
58WNK30.92892581
59STK30.91018630
60OXSR10.88420398
61PASK0.87650944
62PLK10.87463695
63NEK60.86246752
64RPS6KA40.85587415
65CDK80.85098933
66PRPF4B0.83907294
67PBK0.83646897
68DAPK10.83358335
69TESK20.83309786
70TLK10.81954573
71RPS6KA50.79296547
72IRAK10.78742209
73TNK20.78071529
74ATR0.75753231
75MYLK0.75668887
76STK390.73369044
77PINK10.72783389
78AURKA0.72223647
79PNCK0.71599730
80IRAK20.70364470
81PIM20.69503133
82PDK20.68702270
83MINK10.68385878
84MAPKAPK50.66317371
85AURKB0.65542997
86DYRK1A0.62791669
87TAF10.61920481
88NME20.60466145
89BRAF0.59032624
90EPHA20.57566694
91CAMK2B0.57421995
92CSNK2A10.57140643
93BRSK10.57112556
94SCYL20.56293817
95MAPK150.55440094
96SGK20.55400467
97CDK190.54496436
98PRKCI0.53565695
99TAOK30.52517263
100CHEK20.52431267
101CDK70.48921021
102PAK30.48806494
103CHEK10.48466583
104NUAK10.46784925
105ADRBK10.43278726
106CSNK2A20.42891004
107UHMK10.42071501
108STK38L0.41854011
109NLK0.41360613
110PRKCE0.40637779
111WNK40.40583444
112ATM0.40541691
113TTK0.39015256
114CSNK1E0.37680185
115FGFR10.37617911
116CAMK2D0.36546592
117CSNK1A10.35053912
118CSNK1G30.34513072
119ARAF0.34426404
120PRKACB0.34086589
121NTRK30.32449646
122TGFBR10.32296346
123CSNK1D0.31486341
124GRK50.30502137
125KIT0.30447092
126LYN0.28476744
127STK40.28263387
128PRKCG0.28108749
129ERBB40.27947568
130CLK10.27914359
131SGK4940.27704123
132SGK2230.27704123
133KSR10.26161794
134CDK10.25924505
135EPHA40.25267758

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030503.87497318
2RNA polymerase_Homo sapiens_hsa030203.67248198
3Ribosome_Homo sapiens_hsa030103.54752409
4Protein export_Homo sapiens_hsa030603.26369822
5Oxidative phosphorylation_Homo sapiens_hsa001903.09415028
6DNA replication_Homo sapiens_hsa030302.67415615
7Parkinsons disease_Homo sapiens_hsa050122.64576121
8Homologous recombination_Homo sapiens_hsa034402.58881580
9Mismatch repair_Homo sapiens_hsa034302.58760017
10Spliceosome_Homo sapiens_hsa030402.48921961
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.34443371
12Pyrimidine metabolism_Homo sapiens_hsa002402.23708659
13Non-homologous end-joining_Homo sapiens_hsa034502.23284357
14Basal transcription factors_Homo sapiens_hsa030222.19930493
15Nucleotide excision repair_Homo sapiens_hsa034202.16284871
16Huntingtons disease_Homo sapiens_hsa050162.11025014
17Fanconi anemia pathway_Homo sapiens_hsa034602.09197346
18Propanoate metabolism_Homo sapiens_hsa006402.07958052
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.99790207
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.93510813
21Base excision repair_Homo sapiens_hsa034101.90005217
22Alzheimers disease_Homo sapiens_hsa050101.80514233
23RNA degradation_Homo sapiens_hsa030181.78427190
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.67517398
25Purine metabolism_Homo sapiens_hsa002301.61478953
26RNA transport_Homo sapiens_hsa030131.60512481
27Selenocompound metabolism_Homo sapiens_hsa004501.51683773
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.48374749
29Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.47358808
30Steroid biosynthesis_Homo sapiens_hsa001001.44372910
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.37502868
32Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.36533563
33SNARE interactions in vesicular transport_Homo sapiens_hsa041301.34457418
34Cell cycle_Homo sapiens_hsa041101.32548054
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.27943753
36Nicotine addiction_Homo sapiens_hsa050331.20842620
37Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.16666670
38Butanoate metabolism_Homo sapiens_hsa006501.11316294
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.10828060
40Folate biosynthesis_Homo sapiens_hsa007901.05581467
41mRNA surveillance pathway_Homo sapiens_hsa030151.04240605
42Pyruvate metabolism_Homo sapiens_hsa006201.03856774
43Phototransduction_Homo sapiens_hsa047441.02956836
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.02696672
45Collecting duct acid secretion_Homo sapiens_hsa049660.99088585
46Nitrogen metabolism_Homo sapiens_hsa009100.95542657
47Peroxisome_Homo sapiens_hsa041460.92941065
48Epstein-Barr virus infection_Homo sapiens_hsa051690.89319321
49Autoimmune thyroid disease_Homo sapiens_hsa053200.87725910
50Allograft rejection_Homo sapiens_hsa053300.84790589
51Vibrio cholerae infection_Homo sapiens_hsa051100.82745182
52Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.82545443
53Primary immunodeficiency_Homo sapiens_hsa053400.82010071
54Taste transduction_Homo sapiens_hsa047420.80605288
55Arachidonic acid metabolism_Homo sapiens_hsa005900.80317927
56Serotonergic synapse_Homo sapiens_hsa047260.80027083
57p53 signaling pathway_Homo sapiens_hsa041150.79122765
58Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.76332169
59Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.73399603
60Asthma_Homo sapiens_hsa053100.72781487
61Sphingolipid metabolism_Homo sapiens_hsa006000.71294043
62Alcoholism_Homo sapiens_hsa050340.69103530
63Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.68350072
64Rheumatoid arthritis_Homo sapiens_hsa053230.67668163
65Fatty acid metabolism_Homo sapiens_hsa012120.64074844
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.63143864
67One carbon pool by folate_Homo sapiens_hsa006700.63036467
68Sulfur metabolism_Homo sapiens_hsa009200.60133278
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.59592966
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.59465581
71Regulation of autophagy_Homo sapiens_hsa041400.59039550
72Systemic lupus erythematosus_Homo sapiens_hsa053220.58129881
73Primary bile acid biosynthesis_Homo sapiens_hsa001200.56973637
74Olfactory transduction_Homo sapiens_hsa047400.55326358
75Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.55293065
76Vitamin B6 metabolism_Homo sapiens_hsa007500.54108828
77Cardiac muscle contraction_Homo sapiens_hsa042600.53579690
78Graft-versus-host disease_Homo sapiens_hsa053320.53237921
79Carbon metabolism_Homo sapiens_hsa012000.52388284
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51479668
81Intestinal immune network for IgA production_Homo sapiens_hsa046720.51201301
82Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.50695835
83TGF-beta signaling pathway_Homo sapiens_hsa043500.50407073
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.49714551
85Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.49687401
86Herpes simplex infection_Homo sapiens_hsa051680.48506227
87N-Glycan biosynthesis_Homo sapiens_hsa005100.48050035
88Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.47622621
89Metabolic pathways_Homo sapiens_hsa011000.47581245
90Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47097213
91Type I diabetes mellitus_Homo sapiens_hsa049400.46472799
92Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45389906
93Morphine addiction_Homo sapiens_hsa050320.45342444
94Other glycan degradation_Homo sapiens_hsa005110.43949080
95Synaptic vesicle cycle_Homo sapiens_hsa047210.43377755
96Hematopoietic cell lineage_Homo sapiens_hsa046400.43280380
97RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.43234781
98Maturity onset diabetes of the young_Homo sapiens_hsa049500.42182162
99Amphetamine addiction_Homo sapiens_hsa050310.41545524
100Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.39309313
101Oocyte meiosis_Homo sapiens_hsa041140.38104856
102Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37143643
103Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.36438741
104Phagosome_Homo sapiens_hsa041450.35124306
105Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34862132
106Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.34763356
107Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.34340555
1082-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.34153250
109Measles_Homo sapiens_hsa051620.32510762
110Transcriptional misregulation in cancer_Homo sapiens_hsa052020.32331709
111Ether lipid metabolism_Homo sapiens_hsa005650.32212582
112Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31919548
113Dopaminergic synapse_Homo sapiens_hsa047280.31789691
114Fatty acid elongation_Homo sapiens_hsa000620.30731345
115Cocaine addiction_Homo sapiens_hsa050300.30431111
116beta-Alanine metabolism_Homo sapiens_hsa004100.27968344
117Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.27732875
118Caffeine metabolism_Homo sapiens_hsa002320.27161003
119Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.27045501
120Fatty acid degradation_Homo sapiens_hsa000710.27006711
121Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.26725856
122Tryptophan metabolism_Homo sapiens_hsa003800.26626289
123Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.26552909
124Linoleic acid metabolism_Homo sapiens_hsa005910.23327095
125Chemical carcinogenesis_Homo sapiens_hsa052040.22897001
126Hippo signaling pathway_Homo sapiens_hsa043900.22773072
127NF-kappa B signaling pathway_Homo sapiens_hsa040640.22618269
128Biosynthesis of amino acids_Homo sapiens_hsa012300.22151130
129GABAergic synapse_Homo sapiens_hsa047270.19641244
130Viral carcinogenesis_Homo sapiens_hsa052030.18379265
131Antigen processing and presentation_Homo sapiens_hsa046120.17040077
132Circadian entrainment_Homo sapiens_hsa047130.16887326
133Glutamatergic synapse_Homo sapiens_hsa047240.16488587
134Retinol metabolism_Homo sapiens_hsa008300.16134045
135Glutathione metabolism_Homo sapiens_hsa004800.15912784
136HTLV-I infection_Homo sapiens_hsa051660.15819402
137Steroid hormone biosynthesis_Homo sapiens_hsa001400.15634534
138Legionellosis_Homo sapiens_hsa051340.15325271
139Circadian rhythm_Homo sapiens_hsa047100.14607948
140Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.14473756
141Wnt signaling pathway_Homo sapiens_hsa043100.14084524

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