

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 5.25266637 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 4.91149254 |
| 3 | maturation of SSU-rRNA (GO:0030490) | 4.76949742 |
| 4 | nucleobase biosynthetic process (GO:0046112) | 4.48037487 |
| 5 | IMP metabolic process (GO:0046040) | 4.41620692 |
| 6 | DNA double-strand break processing (GO:0000729) | 4.39701602 |
| 7 | respiratory chain complex IV assembly (GO:0008535) | 4.34656018 |
| 8 | DNA replication initiation (GO:0006270) | 4.31554512 |
| 9 | purine nucleobase biosynthetic process (GO:0009113) | 4.28458679 |
| 10 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.19773977 |
| 11 | formation of translation preinitiation complex (GO:0001731) | 4.07125201 |
| 12 | mitotic metaphase plate congression (GO:0007080) | 4.04100340 |
| 13 | ribosomal large subunit biogenesis (GO:0042273) | 3.98187005 |
| 14 | negative regulation of fibroblast apoptotic process (GO:2000270) | 3.96341100 |
| 15 | DNA strand elongation (GO:0022616) | 3.95669939 |
| 16 | ribosome assembly (GO:0042255) | 3.93233101 |
| 17 | proteasome assembly (GO:0043248) | 3.91631852 |
| 18 | viral transcription (GO:0019083) | 3.88240737 |
| 19 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.85510038 |
| 20 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.85510038 |
| 21 | IMP biosynthetic process (GO:0006188) | 3.85204337 |
| 22 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.84413060 |
| 23 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.81294293 |
| 24 | DNA ligation (GO:0006266) | 3.81165994 |
| 25 | cullin deneddylation (GO:0010388) | 3.80869996 |
| 26 | translational termination (GO:0006415) | 3.80323011 |
| 27 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.79655570 |
| 28 | DNA unwinding involved in DNA replication (GO:0006268) | 3.77645668 |
| 29 | protein complex biogenesis (GO:0070271) | 3.77495150 |
| 30 | cytochrome complex assembly (GO:0017004) | 3.77329689 |
| 31 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.74504438 |
| 32 | protein deneddylation (GO:0000338) | 3.72764467 |
| 33 | ribosome biogenesis (GO:0042254) | 3.65065233 |
| 34 | histone exchange (GO:0043486) | 3.63010244 |
| 35 | DNA replication checkpoint (GO:0000076) | 3.62846323 |
| 36 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.62012401 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.61472458 |
| 38 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.59259420 |
| 39 | regulation of spindle organization (GO:0090224) | 3.58507572 |
| 40 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.56256061 |
| 41 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.56256061 |
| 42 | NADH dehydrogenase complex assembly (GO:0010257) | 3.56256061 |
| 43 | establishment of integrated proviral latency (GO:0075713) | 3.55357689 |
| 44 | translational elongation (GO:0006414) | 3.54063044 |
| 45 | rRNA modification (GO:0000154) | 3.53633505 |
| 46 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.51759975 |
| 47 | chaperone-mediated protein transport (GO:0072321) | 3.50593863 |
| 48 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.48267635 |
| 49 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.48267635 |
| 50 | protein K6-linked ubiquitination (GO:0085020) | 3.47852469 |
| 51 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.46903555 |
| 52 | rRNA processing (GO:0006364) | 3.44839800 |
| 53 | metaphase plate congression (GO:0051310) | 3.44704989 |
| 54 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.43179720 |
| 55 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.43179720 |
| 56 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.43179720 |
| 57 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.42811723 |
| 58 | ATP synthesis coupled proton transport (GO:0015986) | 3.42811723 |
| 59 | ribosomal small subunit biogenesis (GO:0042274) | 3.41096970 |
| 60 | translational initiation (GO:0006413) | 3.40923095 |
| 61 | CENP-A containing nucleosome assembly (GO:0034080) | 3.40356082 |
| 62 | spliceosomal snRNP assembly (GO:0000387) | 3.40105059 |
| 63 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.39244802 |
| 64 | termination of RNA polymerase III transcription (GO:0006386) | 3.39244802 |
| 65 | platelet dense granule organization (GO:0060155) | 3.39117247 |
| 66 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.38510483 |
| 67 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.38510483 |
| 68 | protein localization to kinetochore (GO:0034501) | 3.38284798 |
| 69 | chromatin remodeling at centromere (GO:0031055) | 3.34738112 |
| 70 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.32615810 |
| 71 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.32615810 |
| 72 | mitotic nuclear envelope disassembly (GO:0007077) | 3.31278377 |
| 73 | rRNA metabolic process (GO:0016072) | 3.31120892 |
| 74 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.30528293 |
| 75 | telomere maintenance via recombination (GO:0000722) | 3.30400925 |
| 76 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.28564942 |
| 77 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.28256785 |
| 78 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.27879188 |
| 79 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.27736554 |
| 80 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.27736554 |
| 81 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.26717463 |
| 82 | spliceosomal complex assembly (GO:0000245) | 3.25752818 |
| 83 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.25719932 |
| 84 | DNA deamination (GO:0045006) | 3.25503483 |
| 85 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.24477636 |
| 86 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.24079684 |
| 87 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.24079684 |
| 88 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.23328299 |
| 89 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.21361415 |
| 90 | cotranslational protein targeting to membrane (GO:0006613) | 3.21286145 |
| 91 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.21249445 |
| 92 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.21040814 |
| 93 | establishment of chromosome localization (GO:0051303) | 3.20894782 |
| 94 | kinetochore organization (GO:0051383) | 3.20751847 |
| 95 | histone mRNA metabolic process (GO:0008334) | 3.20032660 |
| 96 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.19460778 |
| 97 | protein targeting to ER (GO:0045047) | 3.18007176 |
| 98 | tRNA methylation (GO:0030488) | 3.16740254 |
| 99 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.14956890 |
| 100 | mitotic recombination (GO:0006312) | 3.14534793 |
| 101 | protein localization to endoplasmic reticulum (GO:0070972) | 3.14236665 |
| 102 | regulation of histone H3-K9 methylation (GO:0051570) | 3.10489096 |
| 103 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.10231909 |
| 104 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.08705391 |
| 105 | regulation of mitochondrial translation (GO:0070129) | 3.06943029 |
| 106 | respiratory electron transport chain (GO:0022904) | 3.06454650 |
| 107 | negative regulation of histone methylation (GO:0031061) | 3.06350909 |
| 108 | nuclear envelope disassembly (GO:0051081) | 3.06279842 |
| 109 | membrane disassembly (GO:0030397) | 3.06279842 |
| 110 | pseudouridine synthesis (GO:0001522) | 3.05859634 |
| 111 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.05817011 |
| 112 | rRNA methylation (GO:0031167) | 3.05718464 |
| 113 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.02325137 |
| 114 | telomere maintenance via telomere lengthening (GO:0010833) | 3.02225853 |
| 115 | maturation of 5.8S rRNA (GO:0000460) | 3.01079642 |
| 116 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.99943803 |
| 117 | electron transport chain (GO:0022900) | 2.99800720 |
| 118 | cellular protein complex disassembly (GO:0043624) | 2.99084401 |
| 119 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.98567028 |
| 120 | DNA replication-independent nucleosome organization (GO:0034724) | 2.98567028 |
| 121 | L-fucose catabolic process (GO:0042355) | 2.97518796 |
| 122 | fucose catabolic process (GO:0019317) | 2.97518796 |
| 123 | L-fucose metabolic process (GO:0042354) | 2.97518796 |
| 124 | viral life cycle (GO:0019058) | 2.96480723 |
| 125 | translation (GO:0006412) | 2.96010260 |
| 126 | centriole replication (GO:0007099) | 2.95390335 |
| 127 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.94231695 |
| 128 | cellular component biogenesis (GO:0044085) | 2.93432353 |
| 129 | positive regulation of ligase activity (GO:0051351) | 2.93427097 |
| 130 | protein localization to chromosome, centromeric region (GO:0071459) | 2.93351736 |
| 131 | replication fork processing (GO:0031297) | 2.92216621 |
| 132 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.90064538 |
| 133 | negative regulation of ligase activity (GO:0051352) | 2.90064538 |
| 134 | mitotic sister chromatid segregation (GO:0000070) | 2.90055925 |
| 135 | polyketide metabolic process (GO:0030638) | 2.89233655 |
| 136 | doxorubicin metabolic process (GO:0044598) | 2.89233655 |
| 137 | daunorubicin metabolic process (GO:0044597) | 2.89233655 |
| 138 | mitochondrial RNA metabolic process (GO:0000959) | 2.87550067 |
| 139 | anterograde synaptic vesicle transport (GO:0048490) | 2.87137942 |
| 140 | cell cycle G1/S phase transition (GO:0044843) | 2.86858175 |
| 141 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.86858175 |
| 142 | mitotic G2/M transition checkpoint (GO:0044818) | 2.86708249 |
| 143 | tRNA processing (GO:0008033) | 2.86586916 |
| 144 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.86193591 |
| 145 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.84019178 |
| 146 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.82901311 |
| 147 | kinetochore assembly (GO:0051382) | 2.82823151 |
| 148 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.82701262 |
| 149 | isotype switching (GO:0045190) | 2.82701262 |
| 150 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.82701262 |
| 151 | termination of RNA polymerase I transcription (GO:0006363) | 2.80720693 |
| 152 | RNA methylation (GO:0001510) | 2.80565876 |
| 153 | aldehyde catabolic process (GO:0046185) | 2.78747576 |
| 154 | resolution of meiotic recombination intermediates (GO:0000712) | 2.78113112 |
| 155 | recombinational repair (GO:0000725) | 2.76794563 |
| 156 | inner mitochondrial membrane organization (GO:0007007) | 2.76625581 |
| 157 | spindle checkpoint (GO:0031577) | 2.75931249 |
| 158 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.74900593 |
| 159 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.74346397 |
| 160 | double-strand break repair via homologous recombination (GO:0000724) | 2.74066170 |
| 161 | organelle disassembly (GO:1903008) | 2.71815207 |
| 162 | establishment of viral latency (GO:0019043) | 2.70914470 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.62204412 |
| 2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.27302738 |
| 3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.65070853 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.44799814 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.41901762 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.27768029 |
| 7 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.20653176 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.03476830 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.01457563 |
| 10 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.00597765 |
| 11 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.91974922 |
| 12 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.82049551 |
| 13 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.81155251 |
| 14 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.78184800 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.70084974 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.66388953 |
| 17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.55649771 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.52505539 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.40859684 |
| 20 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.31784065 |
| 21 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.24912702 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.23340339 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.23271825 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.16108359 |
| 25 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.12487871 |
| 26 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.07684437 |
| 27 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.04837640 |
| 28 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.02802339 |
| 29 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.99386118 |
| 30 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.98498166 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.97643843 |
| 32 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.93978151 |
| 33 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.92824497 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.90227332 |
| 35 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.89270065 |
| 36 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.88679155 |
| 37 | FUS_26573619_Chip-Seq_HEK293_Human | 1.84956729 |
| 38 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.82637762 |
| 39 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.82343282 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.81887759 |
| 41 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.81680652 |
| 42 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.80896985 |
| 43 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.79548610 |
| 44 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.78867165 |
| 45 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.76479309 |
| 46 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.73705074 |
| 47 | VDR_22108803_ChIP-Seq_LS180_Human | 1.72938336 |
| 48 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.72065565 |
| 49 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.69680128 |
| 50 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.69470500 |
| 51 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.68003611 |
| 52 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.67538636 |
| 53 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.66627872 |
| 54 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.66550197 |
| 55 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.66280160 |
| 56 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.64875445 |
| 57 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.64569229 |
| 58 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.60916638 |
| 59 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.54360596 |
| 60 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.49355325 |
| 61 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.47030738 |
| 62 | MYC_22102868_ChIP-Seq_BL_Human | 1.45978195 |
| 63 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.44568234 |
| 64 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.43835356 |
| 65 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.41101868 |
| 66 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.41076412 |
| 67 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.41012859 |
| 68 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40067053 |
| 69 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.35690159 |
| 70 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.34014175 |
| 71 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.28308888 |
| 72 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.27573854 |
| 73 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.26261056 |
| 74 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.25823365 |
| 75 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.24129195 |
| 76 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.23743663 |
| 77 | P300_19829295_ChIP-Seq_ESCs_Human | 1.23097679 |
| 78 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.22540514 |
| 79 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.20991733 |
| 80 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.20795955 |
| 81 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.20122020 |
| 82 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.18998716 |
| 83 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.17893576 |
| 84 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.16566461 |
| 85 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.16277776 |
| 86 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.16044630 |
| 87 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.12240126 |
| 88 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.10499777 |
| 89 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.10021812 |
| 90 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.09252666 |
| 91 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.08968092 |
| 92 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.07674055 |
| 93 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.07471213 |
| 94 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.06973375 |
| 95 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.06523706 |
| 96 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.05991196 |
| 97 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05749406 |
| 98 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.05034946 |
| 99 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.05034946 |
| 100 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.04602808 |
| 101 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.02687121 |
| 102 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.01878372 |
| 103 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00702150 |
| 104 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.00393638 |
| 105 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.97867131 |
| 106 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.95974108 |
| 107 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.95403508 |
| 108 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.95184700 |
| 109 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.94998459 |
| 110 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.93510200 |
| 111 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.91077835 |
| 112 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.89418927 |
| 113 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.89228482 |
| 114 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.88965426 |
| 115 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.88786822 |
| 116 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.87853439 |
| 117 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.87266448 |
| 118 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.86863754 |
| 119 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.86811022 |
| 120 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.86677792 |
| 121 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.86661651 |
| 122 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.86030318 |
| 123 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.85658781 |
| 124 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.85160534 |
| 125 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.84928268 |
| 126 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.84606801 |
| 127 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.84060458 |
| 128 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.83393739 |
| 129 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.82175533 |
| 130 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.80996035 |
| 131 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.80782926 |
| 132 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.80353794 |
| 133 | AR_20517297_ChIP-Seq_VCAP_Human | 0.79702651 |
| 134 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.79405831 |
| 135 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.78810974 |
| 136 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.76899840 |
| 137 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76798806 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 5.41635902 |
| 2 | MP0004957_abnormal_blastocyst_morpholog | 4.54160659 |
| 3 | MP0010094_abnormal_chromosome_stability | 4.36713793 |
| 4 | MP0003111_abnormal_nucleus_morphology | 3.73995734 |
| 5 | MP0003077_abnormal_cell_cycle | 3.70862763 |
| 6 | MP0008058_abnormal_DNA_repair | 3.19242678 |
| 7 | MP0008057_abnormal_DNA_replication | 3.08825101 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.80580679 |
| 9 | MP0005408_hypopigmentation | 2.75130416 |
| 10 | MP0002396_abnormal_hematopoietic_system | 2.71541717 |
| 11 | MP0005075_abnormal_melanosome_morpholog | 2.60023312 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 2.53512884 |
| 13 | MP0003718_maternal_effect | 2.43103832 |
| 14 | MP0002938_white_spotting | 2.40548789 |
| 15 | MP0008877_abnormal_DNA_methylation | 2.31363021 |
| 16 | MP0008007_abnormal_cellular_replicative | 2.25051822 |
| 17 | MP0001730_embryonic_growth_arrest | 2.24134726 |
| 18 | MP0003123_paternal_imprinting | 2.17385543 |
| 19 | MP0008932_abnormal_embryonic_tissue | 2.05308884 |
| 20 | MP0010352_gastrointestinal_tract_polyps | 2.03363756 |
| 21 | MP0004808_abnormal_hematopoietic_stem | 2.02473345 |
| 22 | MP0009333_abnormal_splenocyte_physiolog | 2.01075456 |
| 23 | MP0000490_abnormal_crypts_of | 1.98679987 |
| 24 | MP0001293_anophthalmia | 1.97297077 |
| 25 | MP0000350_abnormal_cell_proliferation | 1.95416707 |
| 26 | MP0003787_abnormal_imprinting | 1.92470076 |
| 27 | MP0003763_abnormal_thymus_physiology | 1.80496749 |
| 28 | MP0005397_hematopoietic_system_phenotyp | 1.76566369 |
| 29 | MP0001545_abnormal_hematopoietic_system | 1.76566369 |
| 30 | MP0005253_abnormal_eye_physiology | 1.75824019 |
| 31 | MP0005084_abnormal_gallbladder_morpholo | 1.71256104 |
| 32 | MP0006292_abnormal_olfactory_placode | 1.68725921 |
| 33 | MP0002102_abnormal_ear_morphology | 1.67931504 |
| 34 | MP0003890_abnormal_embryonic-extraembry | 1.66726595 |
| 35 | MP0003786_premature_aging | 1.66498983 |
| 36 | MP0001529_abnormal_vocalization | 1.64503046 |
| 37 | MP0002736_abnormal_nociception_after | 1.63404820 |
| 38 | MP0008789_abnormal_olfactory_epithelium | 1.63248348 |
| 39 | MP0002398_abnormal_bone_marrow | 1.62542757 |
| 40 | MP0006036_abnormal_mitochondrial_physio | 1.62240437 |
| 41 | MP0000689_abnormal_spleen_morphology | 1.61787454 |
| 42 | MP0010307_abnormal_tumor_latency | 1.61421534 |
| 43 | MP0002722_abnormal_immune_system | 1.56752229 |
| 44 | MP0002019_abnormal_tumor_incidence | 1.56446501 |
| 45 | MP0006054_spinal_hemorrhage | 1.51459318 |
| 46 | MP0000703_abnormal_thymus_morphology | 1.50524358 |
| 47 | MP0004084_abnormal_cardiac_muscle | 1.49236254 |
| 48 | MP0008995_early_reproductive_senescence | 1.48834588 |
| 49 | MP0002080_prenatal_lethality | 1.45029550 |
| 50 | MP0001697_abnormal_embryo_size | 1.44814977 |
| 51 | MP0001672_abnormal_embryogenesis/_devel | 1.41287141 |
| 52 | MP0005380_embryogenesis_phenotype | 1.41287141 |
| 53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.39852059 |
| 54 | MP0001984_abnormal_olfaction | 1.39274379 |
| 55 | MP0000313_abnormal_cell_death | 1.39234635 |
| 56 | MP0003195_calcinosis | 1.37710096 |
| 57 | MP0001919_abnormal_reproductive_system | 1.32734128 |
| 58 | MP0003011_delayed_dark_adaptation | 1.31448724 |
| 59 | MP0005174_abnormal_tail_pigmentation | 1.31376809 |
| 60 | MP0000516_abnormal_urinary_system | 1.29793202 |
| 61 | MP0005367_renal/urinary_system_phenotyp | 1.29793202 |
| 62 | MP0001485_abnormal_pinna_reflex | 1.29557839 |
| 63 | MP0003984_embryonic_growth_retardation | 1.29166492 |
| 64 | MP0000631_abnormal_neuroendocrine_gland | 1.27527515 |
| 65 | MP0005551_abnormal_eye_electrophysiolog | 1.27205497 |
| 66 | MP0000372_irregular_coat_pigmentation | 1.24993061 |
| 67 | MP0003656_abnormal_erythrocyte_physiolo | 1.24753819 |
| 68 | MP0002088_abnormal_embryonic_growth/wei | 1.23303563 |
| 69 | MP0002086_abnormal_extraembryonic_tissu | 1.22762452 |
| 70 | MP0002837_dystrophic_cardiac_calcinosis | 1.20974643 |
| 71 | MP0002429_abnormal_blood_cell | 1.20718742 |
| 72 | MP0001324_abnormal_eye_pigmentation | 1.19899668 |
| 73 | MP0003186_abnormal_redox_activity | 1.17906146 |
| 74 | MP0005671_abnormal_response_to | 1.17429033 |
| 75 | MP0003943_abnormal_hepatobiliary_system | 1.16109677 |
| 76 | MP0003252_abnormal_bile_duct | 1.13741641 |
| 77 | MP0004133_heterotaxia | 1.11993088 |
| 78 | MP0001800_abnormal_humoral_immune | 1.10550396 |
| 79 | MP0002751_abnormal_autonomic_nervous | 1.10314345 |
| 80 | MP0003121_genomic_imprinting | 1.10167872 |
| 81 | MP0000716_abnormal_immune_system | 1.09760383 |
| 82 | MP0002090_abnormal_vision | 1.09160408 |
| 83 | MP0001764_abnormal_homeostasis | 1.08330273 |
| 84 | MP0005394_taste/olfaction_phenotype | 1.07696614 |
| 85 | MP0005499_abnormal_olfactory_system | 1.07696614 |
| 86 | MP0009379_abnormal_foot_pigmentation | 1.06895008 |
| 87 | MP0001968_abnormal_touch/_nociception | 1.06808297 |
| 88 | MP0003937_abnormal_limbs/digits/tail_de | 1.05727083 |
| 89 | MP0002085_abnormal_embryonic_tissue | 1.03981145 |
| 90 | MP0003300_gastrointestinal_ulcer | 1.02814555 |
| 91 | MP0003880_abnormal_central_pattern | 1.02232844 |
| 92 | MP0002877_abnormal_melanocyte_morpholog | 1.02167563 |
| 93 | MP0005391_vision/eye_phenotype | 1.02005399 |
| 94 | MP0000465_gastrointestinal_hemorrhage | 1.01643524 |
| 95 | MP0009785_altered_susceptibility_to | 1.00184251 |
| 96 | MP0002132_abnormal_respiratory_system | 0.99402388 |
| 97 | MP0002084_abnormal_developmental_patter | 0.97618818 |
| 98 | MP0002277_abnormal_respiratory_mucosa | 0.96506976 |
| 99 | MP0005389_reproductive_system_phenotype | 0.96308958 |
| 100 | MP0002210_abnormal_sex_determination | 0.95816251 |
| 101 | MP0000569_abnormal_digit_pigmentation | 0.95148995 |
| 102 | MP0002420_abnormal_adaptive_immunity | 0.93465985 |
| 103 | MP0002095_abnormal_skin_pigmentation | 0.90382980 |
| 104 | MP0008875_abnormal_xenobiotic_pharmacok | 0.90368842 |
| 105 | MP0001145_abnormal_male_reproductive | 0.90265793 |
| 106 | MP0005410_abnormal_fertilization | 0.89169981 |
| 107 | MP0006035_abnormal_mitochondrial_morpho | 0.88769668 |
| 108 | MP0003941_abnormal_skin_development | 0.88693517 |
| 109 | MP0001819_abnormal_immune_cell | 0.88685967 |
| 110 | MP0008872_abnormal_physiological_respon | 0.88260891 |
| 111 | MP0000477_abnormal_intestine_morphology | 0.87112411 |
| 112 | MP0003724_increased_susceptibility_to | 0.87046850 |
| 113 | MP0003221_abnormal_cardiomyocyte_apopto | 0.86005111 |
| 114 | MP0000858_altered_metastatic_potential | 0.85646050 |
| 115 | MP0003698_abnormal_male_reproductive | 0.85450880 |
| 116 | MP0000371_diluted_coat_color | 0.85361688 |
| 117 | MP0002723_abnormal_immune_serum | 0.84979309 |
| 118 | MP0002160_abnormal_reproductive_system | 0.84162971 |
| 119 | MP0000566_synostosis | 0.83686126 |
| 120 | MP0002928_abnormal_bile_duct | 0.82780329 |
| 121 | MP0000653_abnormal_sex_gland | 0.82043617 |
| 122 | MP0000358_abnormal_cell_content/ | 0.81351644 |
| 123 | MP0002075_abnormal_coat/hair_pigmentati | 0.80193538 |
| 124 | MP0004885_abnormal_endolymph | 0.80048896 |
| 125 | MP0001929_abnormal_gametogenesis | 0.79529483 |
| 126 | MP0009697_abnormal_copulation | 0.79323011 |
| 127 | MP0002452_abnormal_antigen_presenting | 0.79140622 |
| 128 | MP0010155_abnormal_intestine_physiology | 0.78983141 |
| 129 | MP0004197_abnormal_fetal_growth/weight/ | 0.77467385 |
| 130 | MP0003866_abnormal_defecation | 0.77047094 |
| 131 | MP0000598_abnormal_liver_morphology | 0.77009764 |
| 132 | MP0001119_abnormal_female_reproductive | 0.76672950 |
| 133 | MP0004215_abnormal_myocardial_fiber | 0.75176927 |
| 134 | MP0005266_abnormal_metabolism | 0.75064953 |
| 135 | MP0004147_increased_porphyrin_level | 0.74842080 |
| 136 | MP0000015_abnormal_ear_pigmentation | 0.74600911 |
| 137 | MP0002234_abnormal_pharynx_morphology | 0.72646394 |
| 138 | MP0005464_abnormal_platelet_physiology | 0.72596063 |
| 139 | MP0003315_abnormal_perineum_morphology | 0.72359848 |
| 140 | MP0001186_pigmentation_phenotype | 0.72152905 |
| 141 | MP0010234_abnormal_vibrissa_follicle | 0.71382916 |
| 142 | MP0001915_intracranial_hemorrhage | 0.70676140 |
| 143 | MP0005332_abnormal_amino_acid | 0.70109012 |
| 144 | MP0005000_abnormal_immune_tolerance | 0.69719993 |
| 145 | MP0003436_decreased_susceptibility_to | 0.69062459 |
| 146 | MP0001835_abnormal_antigen_presentation | 0.68814926 |
| 147 | MP0005384_cellular_phenotype | 0.66092760 |
| 148 | MP0000049_abnormal_middle_ear | 0.65515860 |
| 149 | MP0008469_abnormal_protein_level | 0.65484111 |
| 150 | MP0005646_abnormal_pituitary_gland | 0.65374913 |
| 151 | MP0004036_abnormal_muscle_relaxation | 0.64472789 |
| 152 | MP0005195_abnormal_posterior_eye | 0.62619224 |
| 153 | MP0002254_reproductive_system_inflammat | 0.62173811 |
| 154 | MP0002166_altered_tumor_susceptibility | 0.61665994 |
| 155 | MP0005645_abnormal_hypothalamus_physiol | 0.61521401 |
| 156 | MP0002233_abnormal_nose_morphology | 0.60935597 |
| 157 | MP0005395_other_phenotype | 0.60398129 |
| 158 | MP0005621_abnormal_cell_physiology | 0.59909002 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Birth length less than 3rd percentile (HP:0003561) | 6.24423594 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.45906934 |
| 3 | Breast hypoplasia (HP:0003187) | 4.34987287 |
| 4 | Abnormal number of erythroid precursors (HP:0012131) | 4.30629944 |
| 5 | Visual hallucinations (HP:0002367) | 4.05004515 |
| 6 | Absent thumb (HP:0009777) | 4.04741882 |
| 7 | Aplastic anemia (HP:0001915) | 4.03167329 |
| 8 | Amyotrophic lateral sclerosis (HP:0007354) | 3.60587291 |
| 9 | Reticulocytopenia (HP:0001896) | 3.57331429 |
| 10 | Distal arthrogryposis (HP:0005684) | 3.53708177 |
| 11 | Ankle contracture (HP:0006466) | 3.45194033 |
| 12 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 3.39114945 |
| 13 | Thrombocytosis (HP:0001894) | 3.38345768 |
| 14 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 3.25703910 |
| 15 | Acute encephalopathy (HP:0006846) | 3.25392212 |
| 16 | Myelodysplasia (HP:0002863) | 3.17806852 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 3.14169290 |
| 18 | Abnormality of the distal phalanges of the toes (HP:0010182) | 3.10766627 |
| 19 | Methylmalonic acidemia (HP:0002912) | 3.09128763 |
| 20 | B lymphocytopenia (HP:0010976) | 3.08117189 |
| 21 | Glossoptosis (HP:0000162) | 3.02535939 |
| 22 | Progressive macrocephaly (HP:0004481) | 3.01806965 |
| 23 | Colon cancer (HP:0003003) | 2.98013668 |
| 24 | IgM deficiency (HP:0002850) | 2.96625271 |
| 25 | Basal cell carcinoma (HP:0002671) | 2.94300635 |
| 26 | Methylmalonic aciduria (HP:0012120) | 2.90744038 |
| 27 | Agnosia (HP:0010524) | 2.87144164 |
| 28 | Oral leukoplakia (HP:0002745) | 2.87081016 |
| 29 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.81225062 |
| 30 | Abnormality of B cell number (HP:0010975) | 2.81029124 |
| 31 | Chromsome breakage (HP:0040012) | 2.77570330 |
| 32 | Renal Fanconi syndrome (HP:0001994) | 2.74430546 |
| 33 | Broad alveolar ridges (HP:0000187) | 2.72418365 |
| 34 | Abnormality of the anterior horn cell (HP:0006802) | 2.70676508 |
| 35 | Degeneration of anterior horn cells (HP:0002398) | 2.70676508 |
| 36 | Abnormality of serum amino acid levels (HP:0003112) | 2.68528716 |
| 37 | Increased serum lactate (HP:0002151) | 2.64894119 |
| 38 | Increased intramyocellular lipid droplets (HP:0012240) | 2.64042876 |
| 39 | Macrocytic anemia (HP:0001972) | 2.62873143 |
| 40 | Patellar aplasia (HP:0006443) | 2.61486626 |
| 41 | Ependymoma (HP:0002888) | 2.57104304 |
| 42 | Hepatic necrosis (HP:0002605) | 2.54032157 |
| 43 | Hypoplastic pelvis (HP:0008839) | 2.53589616 |
| 44 | Cerebral edema (HP:0002181) | 2.52833423 |
| 45 | Pallor (HP:0000980) | 2.51672298 |
| 46 | Hepatocellular necrosis (HP:0001404) | 2.48557015 |
| 47 | Microvesicular hepatic steatosis (HP:0001414) | 2.48146075 |
| 48 | Microretrognathia (HP:0000308) | 2.47701711 |
| 49 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.47537508 |
| 50 | Rough bone trabeculation (HP:0100670) | 2.46834157 |
| 51 | Septo-optic dysplasia (HP:0100842) | 2.46237217 |
| 52 | Axonal loss (HP:0003447) | 2.43380729 |
| 53 | Pancreatic cysts (HP:0001737) | 2.38999303 |
| 54 | Abnormal lung lobation (HP:0002101) | 2.38988873 |
| 55 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.38082449 |
| 56 | Amaurosis fugax (HP:0100576) | 2.37024289 |
| 57 | Pancytopenia (HP:0001876) | 2.34841523 |
| 58 | Abnormality of the preputium (HP:0100587) | 2.33405532 |
| 59 | Abnormality of midbrain morphology (HP:0002418) | 2.33214248 |
| 60 | Molar tooth sign on MRI (HP:0002419) | 2.33214248 |
| 61 | Sparse eyelashes (HP:0000653) | 2.32942040 |
| 62 | Abnormality of methionine metabolism (HP:0010901) | 2.32863877 |
| 63 | Pancreatic fibrosis (HP:0100732) | 2.32745493 |
| 64 | True hermaphroditism (HP:0010459) | 2.32495503 |
| 65 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.31099863 |
| 66 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.31099863 |
| 67 | Increased hepatocellular lipid droplets (HP:0006565) | 2.28972279 |
| 68 | Gonadotropin excess (HP:0000837) | 2.28669582 |
| 69 | Oligodactyly (hands) (HP:0001180) | 2.28464264 |
| 70 | Bone marrow hypocellularity (HP:0005528) | 2.27621311 |
| 71 | Medulloblastoma (HP:0002885) | 2.27601273 |
| 72 | Increased CSF lactate (HP:0002490) | 2.23708426 |
| 73 | Abnormality of chromosome stability (HP:0003220) | 2.23521837 |
| 74 | Adactyly (HP:0009776) | 2.22732893 |
| 75 | Carpal bone hypoplasia (HP:0001498) | 2.21440818 |
| 76 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.21098133 |
| 77 | Nephronophthisis (HP:0000090) | 2.19044987 |
| 78 | Peripheral hypomyelination (HP:0007182) | 2.18345668 |
| 79 | Abnormal neuron morphology (HP:0012757) | 2.16350437 |
| 80 | Abnormality of the motor neurons (HP:0002450) | 2.16350437 |
| 81 | Medial flaring of the eyebrow (HP:0010747) | 2.14604329 |
| 82 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.14587421 |
| 83 | Sparse scalp hair (HP:0002209) | 2.13869218 |
| 84 | Premature graying of hair (HP:0002216) | 2.12782079 |
| 85 | Mitochondrial inheritance (HP:0001427) | 2.12437701 |
| 86 | IgG deficiency (HP:0004315) | 2.10847100 |
| 87 | Multiple enchondromatosis (HP:0005701) | 2.09376778 |
| 88 | Lipid accumulation in hepatocytes (HP:0006561) | 2.08027771 |
| 89 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.07989157 |
| 90 | 11 pairs of ribs (HP:0000878) | 2.07932662 |
| 91 | Cerebral hypomyelination (HP:0006808) | 2.07851639 |
| 92 | Exertional dyspnea (HP:0002875) | 2.06445774 |
| 93 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.05934178 |
| 94 | Supernumerary spleens (HP:0009799) | 2.05458893 |
| 95 | Slender long bone (HP:0003100) | 2.04616665 |
| 96 | Meckel diverticulum (HP:0002245) | 2.03835022 |
| 97 | Posterior subcapsular cataract (HP:0007787) | 2.03641760 |
| 98 | Bile duct proliferation (HP:0001408) | 2.03381077 |
| 99 | Abnormal biliary tract physiology (HP:0012439) | 2.03381077 |
| 100 | Neoplasm of the pancreas (HP:0002894) | 2.03281863 |
| 101 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.00734530 |
| 102 | Cellular immunodeficiency (HP:0005374) | 1.99856088 |
| 103 | Increased muscle lipid content (HP:0009058) | 1.98580679 |
| 104 | Congenital primary aphakia (HP:0007707) | 1.97827072 |
| 105 | Impulsivity (HP:0100710) | 1.96023760 |
| 106 | Lactic acidosis (HP:0003128) | 1.95954785 |
| 107 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.95357082 |
| 108 | Lymphoma (HP:0002665) | 1.95104701 |
| 109 | Exercise intolerance (HP:0003546) | 1.94433019 |
| 110 | Abnormality of the duodenum (HP:0002246) | 1.93396452 |
| 111 | Congenital, generalized hypertrichosis (HP:0004540) | 1.93112219 |
| 112 | Chronic hepatic failure (HP:0100626) | 1.92942967 |
| 113 | Respiratory difficulties (HP:0002880) | 1.92060099 |
| 114 | Asplenia (HP:0001746) | 1.91850422 |
| 115 | Rhabdomyosarcoma (HP:0002859) | 1.91741884 |
| 116 | Renal cortical cysts (HP:0000803) | 1.91447285 |
| 117 | Respiratory failure (HP:0002878) | 1.91164889 |
| 118 | Nephrogenic diabetes insipidus (HP:0009806) | 1.91052916 |
| 119 | Abnormality of T cell physiology (HP:0011840) | 1.90806194 |
| 120 | Intestinal atresia (HP:0011100) | 1.90632631 |
| 121 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.89872235 |
| 122 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.89823861 |
| 123 | Abnormality of alanine metabolism (HP:0010916) | 1.89823861 |
| 124 | Hyperalaninemia (HP:0003348) | 1.89823861 |
| 125 | Abnormality of the labia minora (HP:0012880) | 1.89191260 |
| 126 | Poikiloderma (HP:0001029) | 1.89083651 |
| 127 | Absent septum pellucidum (HP:0001331) | 1.88783221 |
| 128 | Lethargy (HP:0001254) | 1.87989411 |
| 129 | Hypoplasia of the pons (HP:0012110) | 1.87070943 |
| 130 | Acute necrotizing encephalopathy (HP:0006965) | 1.86567872 |
| 131 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.86492423 |
| 132 | Abnormality of the alveolar ridges (HP:0006477) | 1.86466355 |
| 133 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.85989046 |
| 134 | Gait imbalance (HP:0002141) | 1.85553205 |
| 135 | Type I transferrin isoform profile (HP:0003642) | 1.85372951 |
| 136 | Duodenal stenosis (HP:0100867) | 1.84785188 |
| 137 | Small intestinal stenosis (HP:0012848) | 1.84785188 |
| 138 | Severe global developmental delay (HP:0011344) | 1.84732952 |
| 139 | Abnormality of the pons (HP:0007361) | 1.84682954 |
| 140 | Optic disc pallor (HP:0000543) | 1.84536257 |
| 141 | Hyperglycinemia (HP:0002154) | 1.84502128 |
| 142 | Abnormality of T cells (HP:0002843) | 1.84494554 |
| 143 | Decreased skull ossification (HP:0004331) | 1.83250279 |
| 144 | CNS demyelination (HP:0007305) | 1.83193333 |
| 145 | Abnormality of the ileum (HP:0001549) | 1.81081426 |
| 146 | Volvulus (HP:0002580) | 1.80724499 |
| 147 | Leukodystrophy (HP:0002415) | 1.79628545 |
| 148 | Hyperphosphaturia (HP:0003109) | 1.79264603 |
| 149 | Abnormality of glycolysis (HP:0004366) | 1.78493989 |
| 150 | Increased serum pyruvate (HP:0003542) | 1.78493989 |
| 151 | Sloping forehead (HP:0000340) | 1.76247674 |
| 152 | Abnormality of renal resorption (HP:0011038) | 1.75893071 |
| 153 | Abnormal protein glycosylation (HP:0012346) | 1.75593344 |
| 154 | Abnormal glycosylation (HP:0012345) | 1.75593344 |
| 155 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.75593344 |
| 156 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.75593344 |
| 157 | Triphalangeal thumb (HP:0001199) | 1.74854055 |
| 158 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.74405979 |
| 159 | Median cleft lip (HP:0000161) | 1.74266519 |
| 160 | Homocystinuria (HP:0002156) | 1.72365987 |
| 161 | Abnormality of homocysteine metabolism (HP:0010919) | 1.72365987 |
| 162 | Optic nerve hypoplasia (HP:0000609) | 1.71591737 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 4.36907544 |
| 2 | WEE1 | 4.05415296 |
| 3 | PIK3CG | 3.85964567 |
| 4 | CDC7 | 3.45196514 |
| 5 | EIF2AK1 | 3.33141012 |
| 6 | TRIM28 | 2.89079762 |
| 7 | STK16 | 2.72292886 |
| 8 | TSSK6 | 2.70054192 |
| 9 | WNK3 | 2.57610037 |
| 10 | NUAK1 | 2.49856619 |
| 11 | VRK2 | 2.49242640 |
| 12 | ACVR1B | 2.25057829 |
| 13 | MKNK1 | 2.19036231 |
| 14 | SRPK1 | 2.17859852 |
| 15 | BRSK2 | 2.10197433 |
| 16 | RPS6KA4 | 2.07626141 |
| 17 | PBK | 2.05317545 |
| 18 | NEK2 | 1.93247143 |
| 19 | FRK | 1.93197997 |
| 20 | VRK1 | 1.90515406 |
| 21 | EIF2AK3 | 1.87246374 |
| 22 | TNIK | 1.84694190 |
| 23 | TTK | 1.83133490 |
| 24 | CSNK1G1 | 1.77547399 |
| 25 | FLT3 | 1.73256256 |
| 26 | PASK | 1.72983955 |
| 27 | PLK1 | 1.65215521 |
| 28 | BMPR1B | 1.64767956 |
| 29 | NME2 | 1.62891755 |
| 30 | PLK3 | 1.62565579 |
| 31 | NEK1 | 1.60470848 |
| 32 | NLK | 1.58108976 |
| 33 | MAP4K1 | 1.57349639 |
| 34 | STK10 | 1.54824312 |
| 35 | CASK | 1.53036466 |
| 36 | TGFBR1 | 1.48961545 |
| 37 | TESK2 | 1.45915346 |
| 38 | ADRBK2 | 1.44249301 |
| 39 | PLK4 | 1.42184526 |
| 40 | AURKB | 1.40528974 |
| 41 | AKT3 | 1.38879538 |
| 42 | CCNB1 | 1.38664551 |
| 43 | RPS6KB2 | 1.35708495 |
| 44 | MAP3K12 | 1.34109965 |
| 45 | CSNK1G3 | 1.33815058 |
| 46 | BCKDK | 1.28958908 |
| 47 | ERBB3 | 1.27789198 |
| 48 | BRAF | 1.26831249 |
| 49 | ATR | 1.26051513 |
| 50 | MAP3K8 | 1.24925716 |
| 51 | CHEK2 | 1.21396262 |
| 52 | CSNK1G2 | 1.20927796 |
| 53 | GRK1 | 1.19295864 |
| 54 | DYRK3 | 1.18093251 |
| 55 | CSNK1A1L | 1.12336684 |
| 56 | CDK7 | 1.12244267 |
| 57 | AURKA | 1.11062402 |
| 58 | MAP2K3 | 1.10320504 |
| 59 | KIT | 1.05035880 |
| 60 | PRKCI | 1.02120443 |
| 61 | PDK2 | 1.01083829 |
| 62 | MKNK2 | 0.99678317 |
| 63 | MAP4K2 | 0.98201205 |
| 64 | BRSK1 | 0.97799386 |
| 65 | BCR | 0.95573638 |
| 66 | INSRR | 0.95342244 |
| 67 | TLK1 | 0.92703525 |
| 68 | IKBKE | 0.92237896 |
| 69 | BTK | 0.89016199 |
| 70 | PIM1 | 0.88415221 |
| 71 | YES1 | 0.88115620 |
| 72 | TAF1 | 0.86943256 |
| 73 | STK4 | 0.86458364 |
| 74 | PAK4 | 0.85709641 |
| 75 | GRK6 | 0.85649225 |
| 76 | TEC | 0.83221807 |
| 77 | CSNK2A2 | 0.82733973 |
| 78 | PKN2 | 0.80583609 |
| 79 | SCYL2 | 0.76357097 |
| 80 | DYRK2 | 0.76338873 |
| 81 | DAPK1 | 0.73349318 |
| 82 | MAPK13 | 0.71706708 |
| 83 | CHEK1 | 0.71409567 |
| 84 | CDK4 | 0.71208033 |
| 85 | STK3 | 0.70129980 |
| 86 | PLK2 | 0.69391705 |
| 87 | CSNK2A1 | 0.67170221 |
| 88 | MAP3K4 | 0.66606980 |
| 89 | RPS6KA5 | 0.65914123 |
| 90 | TXK | 0.63611371 |
| 91 | TYK2 | 0.61832779 |
| 92 | ALK | 0.60885579 |
| 93 | LRRK2 | 0.59906200 |
| 94 | CDK2 | 0.58201851 |
| 95 | ZAK | 0.58130436 |
| 96 | ATM | 0.57479447 |
| 97 | TAOK3 | 0.55758277 |
| 98 | PRKCG | 0.55270357 |
| 99 | IKBKB | 0.55014073 |
| 100 | MAP2K7 | 0.54985473 |
| 101 | PINK1 | 0.54872064 |
| 102 | OXSR1 | 0.54590267 |
| 103 | TNK2 | 0.54084916 |
| 104 | PRKCE | 0.52988713 |
| 105 | MAP3K3 | 0.52607490 |
| 106 | ARAF | 0.52605867 |
| 107 | LYN | 0.50422456 |
| 108 | CDK19 | 0.50230693 |
| 109 | MELK | 0.50215529 |
| 110 | NME1 | 0.48148582 |
| 111 | SYK | 0.47806664 |
| 112 | EPHA2 | 0.47056227 |
| 113 | PRKCQ | 0.46077396 |
| 114 | CDK8 | 0.44497171 |
| 115 | MAPKAPK3 | 0.43950269 |
| 116 | CDK1 | 0.43871905 |
| 117 | CDK12 | 0.43522220 |
| 118 | ZAP70 | 0.40755172 |
| 119 | EIF2AK2 | 0.39730090 |
| 120 | KDR | 0.39557411 |
| 121 | JAK3 | 0.38274208 |
| 122 | CSNK1A1 | 0.37730803 |
| 123 | MUSK | 0.37667661 |
| 124 | MST4 | 0.37555331 |
| 125 | LIMK1 | 0.37282962 |
| 126 | STK38L | 0.37124929 |
| 127 | PAK1 | 0.36993409 |
| 128 | MAP3K11 | 0.35884972 |
| 129 | MAP2K6 | 0.35858902 |
| 130 | GRK7 | 0.34763012 |
| 131 | CDK6 | 0.34746540 |
| 132 | MYLK | 0.34237409 |
| 133 | CAMKK2 | 0.33914855 |
| 134 | SIK3 | 0.33661374 |
| 135 | EEF2K | 0.30209526 |
| 136 | SGK2 | 0.29174570 |
| 137 | STK39 | 0.28715939 |
| 138 | BMPR2 | 0.28008465 |
| 139 | ADRBK1 | 0.26812520 |
| 140 | CDK9 | 0.26608390 |
| 141 | MAPK11 | 0.24979510 |
| 142 | STK24 | 0.23521705 |
| 143 | CSNK1E | 0.23053917 |
| 144 | ERBB4 | 0.23018787 |
| 145 | MAP3K9 | 0.22670108 |
| 146 | PRKCA | 0.21574141 |
| 147 | WNK4 | 0.21500591 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 4.43096571 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 4.33251500 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.87443948 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.78742061 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 3.69000013 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 3.64383502 |
| 7 | Spliceosome_Homo sapiens_hsa03040 | 3.03114528 |
| 8 | RNA transport_Homo sapiens_hsa03013 | 2.89420520 |
| 9 | Base excision repair_Homo sapiens_hsa03410 | 2.86439686 |
| 10 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.85495145 |
| 11 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.79103901 |
| 12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.75500165 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 2.56372543 |
| 14 | Cell cycle_Homo sapiens_hsa04110 | 2.40624040 |
| 15 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.31478224 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.15352217 |
| 17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.15269114 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 2.00205930 |
| 19 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.72274499 |
| 20 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.70348202 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.66875174 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.58812408 |
| 23 | Purine metabolism_Homo sapiens_hsa00230 | 1.54659889 |
| 24 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.51736935 |
| 25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.40515136 |
| 26 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.34489157 |
| 27 | Protein export_Homo sapiens_hsa03060 | 1.32781179 |
| 28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.27804560 |
| 29 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.27616677 |
| 30 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.27033565 |
| 31 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.22057004 |
| 32 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.18738919 |
| 33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.12969371 |
| 34 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.07034500 |
| 35 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.05360782 |
| 36 | Parkinsons disease_Homo sapiens_hsa05012 | 1.04297242 |
| 37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.02665487 |
| 38 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.00567988 |
| 39 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.99043189 |
| 40 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.98343578 |
| 41 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.96106875 |
| 42 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.95602123 |
| 43 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.94334178 |
| 44 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.92504880 |
| 45 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.88104570 |
| 46 | Huntingtons disease_Homo sapiens_hsa05016 | 0.86966890 |
| 47 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.83070422 |
| 48 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.81477312 |
| 49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.81138766 |
| 50 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.80198457 |
| 51 | Carbon metabolism_Homo sapiens_hsa01200 | 0.79683689 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.77356390 |
| 53 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.75442059 |
| 54 | Phototransduction_Homo sapiens_hsa04744 | 0.75408046 |
| 55 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.75152214 |
| 56 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.74235495 |
| 57 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.70756215 |
| 58 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.69963552 |
| 59 | Sulfur relay system_Homo sapiens_hsa04122 | 0.69689944 |
| 60 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.69302782 |
| 61 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.65507866 |
| 62 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.63187718 |
| 63 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.63086104 |
| 64 | Legionellosis_Homo sapiens_hsa05134 | 0.61670849 |
| 65 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.61317427 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.61223492 |
| 67 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.59797583 |
| 68 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.58569050 |
| 69 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.58450214 |
| 70 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.57985836 |
| 71 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.54608222 |
| 72 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.52611745 |
| 73 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.52433389 |
| 74 | Galactose metabolism_Homo sapiens_hsa00052 | 0.51846632 |
| 75 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.49834511 |
| 76 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48267471 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47543941 |
| 78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47518245 |
| 79 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.47245236 |
| 80 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.46104496 |
| 81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45812861 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45157664 |
| 83 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.44596047 |
| 84 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.44433432 |
| 85 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.43977152 |
| 86 | Metabolic pathways_Homo sapiens_hsa01100 | 0.42766129 |
| 87 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42203540 |
| 88 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.41618824 |
| 89 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.41607225 |
| 90 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.41131408 |
| 91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.40300169 |
| 92 | Thyroid cancer_Homo sapiens_hsa05216 | 0.39360314 |
| 93 | Measles_Homo sapiens_hsa05162 | 0.38787536 |
| 94 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.38669938 |
| 95 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.38241799 |
| 96 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.37192756 |
| 97 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34089930 |
| 98 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.33369701 |
| 99 | Hepatitis B_Homo sapiens_hsa05161 | 0.32738840 |
| 100 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.32640677 |
| 101 | Alzheimers disease_Homo sapiens_hsa05010 | 0.31875947 |
| 102 | HTLV-I infection_Homo sapiens_hsa05166 | 0.31121528 |
| 103 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28124350 |
| 104 | Olfactory transduction_Homo sapiens_hsa04740 | 0.28038848 |
| 105 | Circadian rhythm_Homo sapiens_hsa04710 | 0.27998322 |
| 106 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27483178 |
| 107 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.27129707 |
| 108 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.27074725 |
| 109 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.26047222 |
| 110 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.25580091 |
| 111 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.25058243 |
| 112 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.24375612 |
| 113 | Apoptosis_Homo sapiens_hsa04210 | 0.22536884 |
| 114 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.21372974 |
| 115 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.20932379 |
| 116 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.20755762 |
| 117 | Other glycan degradation_Homo sapiens_hsa00511 | 0.19311952 |
| 118 | Shigellosis_Homo sapiens_hsa05131 | 0.19148372 |
| 119 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.17474094 |
| 120 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.17458679 |
| 121 | Colorectal cancer_Homo sapiens_hsa05210 | 0.16816990 |
| 122 | Alcoholism_Homo sapiens_hsa05034 | 0.16420333 |
| 123 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.15995763 |
| 124 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.13482039 |
| 125 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.11480341 |
| 126 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.10563366 |
| 127 | Influenza A_Homo sapiens_hsa05164 | 0.10356380 |
| 128 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.07511507 |
| 129 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.05422661 |
| 130 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.04334539 |
| 131 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.03374324 |
| 132 | Peroxisome_Homo sapiens_hsa04146 | 0.02471595 |
| 133 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.02460469 |
| 134 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.02035969 |

