| 1 | Birth length less than 3rd percentile (HP:0003561) | 5.32156947 |
| 2 | Impulsivity (HP:0100710) | 4.78401637 |
| 3 | Abnormal hair whorl (HP:0010721) | 4.47269749 |
| 4 | Chromsome breakage (HP:0040012) | 4.35439922 |
| 5 | Abnormality of the fingertips (HP:0001211) | 4.22684233 |
| 6 | Abnormality of the nasal septum (HP:0000419) | 3.94286128 |
| 7 | Abnormality of incisor morphology (HP:0011063) | 3.66797256 |
| 8 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.61879010 |
| 9 | Abnormality of cochlea (HP:0000375) | 3.40460504 |
| 10 | Papillary thyroid carcinoma (HP:0002895) | 3.26656463 |
| 11 | Ectopic kidney (HP:0000086) | 3.17278615 |
| 12 | Cortical dysplasia (HP:0002539) | 3.12974603 |
| 13 | Capillary hemangiomas (HP:0005306) | 3.12616170 |
| 14 | Abnormality of the aortic arch (HP:0012303) | 3.09352418 |
| 15 | Abnormal spermatogenesis (HP:0008669) | 3.05741202 |
| 16 | Breast hypoplasia (HP:0003187) | 3.01381113 |
| 17 | Diastasis recti (HP:0001540) | 3.01331894 |
| 18 | Short middle phalanx of the 5th finger (HP:0004220) | 3.00790779 |
| 19 | Increased hepatocellular lipid droplets (HP:0006565) | 2.98008355 |
| 20 | Patellar aplasia (HP:0006443) | 2.97948659 |
| 21 | Shawl scrotum (HP:0000049) | 2.96174032 |
| 22 | Abnormality of chromosome stability (HP:0003220) | 2.94792892 |
| 23 | Degeneration of anterior horn cells (HP:0002398) | 2.93798368 |
| 24 | Abnormality of the anterior horn cell (HP:0006802) | 2.93798368 |
| 25 | Abnormal lung lobation (HP:0002101) | 2.89662510 |
| 26 | Abnormality of the columella (HP:0009929) | 2.78461889 |
| 27 | Pancreatic cysts (HP:0001737) | 2.78072771 |
| 28 | Azoospermia (HP:0000027) | 2.75139567 |
| 29 | Clubbing of toes (HP:0100760) | 2.73719775 |
| 30 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.69871807 |
| 31 | Abnormality of the incisor (HP:0000676) | 2.68848962 |
| 32 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.67628454 |
| 33 | Embryonal renal neoplasm (HP:0011794) | 2.65126514 |
| 34 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.61240433 |
| 35 | Long eyelashes (HP:0000527) | 2.57819778 |
| 36 | Congenital primary aphakia (HP:0007707) | 2.57532353 |
| 37 | Lipid accumulation in hepatocytes (HP:0006561) | 2.49025014 |
| 38 | Abnormality of the duodenum (HP:0002246) | 2.48325436 |
| 39 | Medial flaring of the eyebrow (HP:0010747) | 2.46930939 |
| 40 | Aplastic anemia (HP:0001915) | 2.46847533 |
| 41 | Deep philtrum (HP:0002002) | 2.46555517 |
| 42 | Gait imbalance (HP:0002141) | 2.45775874 |
| 43 | Nephrogenic diabetes insipidus (HP:0009806) | 2.43930185 |
| 44 | Depressed nasal tip (HP:0000437) | 2.39504050 |
| 45 | Progressive inability to walk (HP:0002505) | 2.32425695 |
| 46 | Acute myeloid leukemia (HP:0004808) | 2.31343728 |
| 47 | Abnormality of the right ventricle (HP:0001707) | 2.30107099 |
| 48 | Hypoplastic iliac wings (HP:0002866) | 2.29747946 |
| 49 | Morphological abnormality of the inner ear (HP:0011390) | 2.27646444 |
| 50 | Myelodysplasia (HP:0002863) | 2.25440515 |
| 51 | Hypoplastic left heart (HP:0004383) | 2.22292302 |
| 52 | Meckel diverticulum (HP:0002245) | 2.21594238 |
| 53 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.19204656 |
| 54 | Thyroid carcinoma (HP:0002890) | 2.18630545 |
| 55 | Abnormality of the preputium (HP:0100587) | 2.17980388 |
| 56 | Abnormality of the parietal bone (HP:0002696) | 2.17632003 |
| 57 | Oral leukoplakia (HP:0002745) | 2.14221841 |
| 58 | Abnormality of male internal genitalia (HP:0000022) | 2.12885561 |
| 59 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.11814583 |
| 60 | Renal cortical cysts (HP:0000803) | 2.10410155 |
| 61 | Glioma (HP:0009733) | 2.08761238 |
| 62 | Astigmatism (HP:0000483) | 2.08680874 |
| 63 | Sloping forehead (HP:0000340) | 2.08588728 |
| 64 | Abnormality of the septum pellucidum (HP:0007375) | 2.07883351 |
| 65 | Abnormality of the prostate (HP:0008775) | 2.06689016 |
| 66 | Abnormality of the ileum (HP:0001549) | 2.06521314 |
| 67 | Lip pit (HP:0100267) | 2.05319361 |
| 68 | Duodenal stenosis (HP:0100867) | 2.04489724 |
| 69 | Small intestinal stenosis (HP:0012848) | 2.04489724 |
| 70 | Truncal obesity (HP:0001956) | 2.03875050 |
| 71 | Progressive macrocephaly (HP:0004481) | 2.01075181 |
| 72 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.00979585 |
| 73 | Amyotrophic lateral sclerosis (HP:0007354) | 2.00194586 |
| 74 | Poikilocytosis (HP:0004447) | 2.00138375 |
| 75 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.99418188 |
| 76 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.99418188 |
| 77 | Supernumerary spleens (HP:0009799) | 1.97453807 |
| 78 | Pulmonary fibrosis (HP:0002206) | 1.97453294 |
| 79 | Rhabdomyosarcoma (HP:0002859) | 1.97452779 |
| 80 | Abnormality of the labia minora (HP:0012880) | 1.96393829 |
| 81 | Volvulus (HP:0002580) | 1.96009854 |
| 82 | Increased nuchal translucency (HP:0010880) | 1.95642859 |
| 83 | Increased CSF lactate (HP:0002490) | 1.95035091 |
| 84 | Long foot (HP:0001833) | 1.94492417 |
| 85 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.93487744 |
| 86 | Genital tract atresia (HP:0001827) | 1.93161573 |
| 87 | Methylmalonic acidemia (HP:0002912) | 1.92850511 |
| 88 | Vaginal atresia (HP:0000148) | 1.90751670 |
| 89 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.90539073 |
| 90 | Abnormality of methionine metabolism (HP:0010901) | 1.89721163 |
| 91 | Obstructive sleep apnea (HP:0002870) | 1.89113110 |
| 92 | Cafe-au-lait spot (HP:0000957) | 1.88700549 |
| 93 | Renal Fanconi syndrome (HP:0001994) | 1.88695243 |
| 94 | Albinism (HP:0001022) | 1.88437995 |
| 95 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.88238514 |
| 96 | Colon cancer (HP:0003003) | 1.87377993 |
| 97 | Hypochromic microcytic anemia (HP:0004840) | 1.86509814 |
| 98 | Abnormality of DNA repair (HP:0003254) | 1.86504898 |
| 99 | Acute necrotizing encephalopathy (HP:0006965) | 1.86443924 |
| 100 | Nephronophthisis (HP:0000090) | 1.86400293 |
| 101 | Abnormality of renal resorption (HP:0011038) | 1.86199727 |
| 102 | Fair hair (HP:0002286) | 1.84798573 |
| 103 | Pancreatic fibrosis (HP:0100732) | 1.84379259 |
| 104 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.84281752 |
| 105 | Respiratory difficulties (HP:0002880) | 1.84028028 |
| 106 | CNS hypomyelination (HP:0003429) | 1.83656990 |
| 107 | Absent thumb (HP:0009777) | 1.83621907 |
| 108 | Aseptic necrosis (HP:0010885) | 1.83127481 |
| 109 | Medulloblastoma (HP:0002885) | 1.83037137 |
| 110 | Abnormal auditory evoked potentials (HP:0006958) | 1.82185520 |
| 111 | Dislocated radial head (HP:0003083) | 1.81854982 |
| 112 | Neoplasm of the adrenal cortex (HP:0100641) | 1.81458534 |
| 113 | Type 2 muscle fiber atrophy (HP:0003554) | 1.80751392 |
| 114 | Absent septum pellucidum (HP:0001331) | 1.80681896 |
| 115 | Hypobetalipoproteinemia (HP:0003563) | 1.80534278 |
| 116 | Duplicated collecting system (HP:0000081) | 1.80443898 |
| 117 | Bone marrow hypocellularity (HP:0005528) | 1.80387841 |
| 118 | Poor coordination (HP:0002370) | 1.80001830 |
| 119 | True hermaphroditism (HP:0010459) | 1.79921769 |
| 120 | Oligodactyly (hands) (HP:0001180) | 1.79142287 |
| 121 | Dandy-Walker malformation (HP:0001305) | 1.77977151 |
| 122 | Neoplasm of the adrenal gland (HP:0100631) | 1.77971463 |
| 123 | Septo-optic dysplasia (HP:0100842) | 1.77626621 |
| 124 | Tongue fasciculations (HP:0001308) | 1.77619266 |
| 125 | Anencephaly (HP:0002323) | 1.76906204 |
| 126 | Abnormality of the renal collecting system (HP:0004742) | 1.76716510 |
| 127 | Acute encephalopathy (HP:0006846) | 1.75830811 |
| 128 | Nasolacrimal duct obstruction (HP:0000579) | 1.74263439 |
| 129 | Optic nerve coloboma (HP:0000588) | 1.74006791 |
| 130 | Postaxial foot polydactyly (HP:0001830) | 1.73596953 |
| 131 | Eosinophilia (HP:0001880) | 1.73404599 |
| 132 | Abnormality of the carotid arteries (HP:0005344) | 1.73307017 |
| 133 | Abnormality of lateral ventricle (HP:0030047) | 1.72655233 |
| 134 | Neoplasm of the colon (HP:0100273) | 1.72065859 |
| 135 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.72007273 |
| 136 | Absent radius (HP:0003974) | 1.71863136 |
| 137 | Median cleft lip (HP:0000161) | 1.71564941 |
| 138 | Aplasia involving forearm bones (HP:0009822) | 1.71284466 |
| 139 | Absent forearm bone (HP:0003953) | 1.71284466 |
| 140 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.71154756 |
| 141 | Drooling (HP:0002307) | 1.70897904 |
| 142 | Acanthocytosis (HP:0001927) | 1.70434215 |
| 143 | Granulocytopenia (HP:0001913) | 1.69919063 |
| 144 | Hypoplastic heart (HP:0001961) | 1.68702105 |
| 145 | Abnormality of midbrain morphology (HP:0002418) | 1.68699826 |
| 146 | Molar tooth sign on MRI (HP:0002419) | 1.68699826 |
| 147 | Optic nerve hypoplasia (HP:0000609) | 1.68399693 |
| 148 | Aqueductal stenosis (HP:0002410) | 1.68091203 |
| 149 | Growth hormone deficiency (HP:0000824) | 1.67608310 |
| 150 | Oligohydramnios (HP:0001562) | 1.67602250 |
| 151 | Arteriovenous malformation (HP:0100026) | 1.67432608 |
| 152 | Limb hypertonia (HP:0002509) | 1.67092196 |
| 153 | Intestinal fistula (HP:0100819) | 1.66895157 |
| 154 | Premature graying of hair (HP:0002216) | 1.66840427 |
| 155 | Breast carcinoma (HP:0003002) | 1.66500914 |
| 156 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.65785660 |
| 157 | Broad foot (HP:0001769) | 1.65132435 |
| 158 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.65050516 |
| 159 | Short 4th metacarpal (HP:0010044) | 1.65050516 |
| 160 | Pelvic girdle muscle weakness (HP:0003749) | 1.64727580 |
| 161 | Excessive salivation (HP:0003781) | 1.64544604 |
| 162 | Cutaneous melanoma (HP:0012056) | 1.64504390 |
| 163 | Horseshoe kidney (HP:0000085) | 1.64430869 |
| 164 | Papilledema (HP:0001085) | 1.64295637 |
| 165 | Broad thumb (HP:0011304) | 1.63772634 |
| 166 | Convex nasal ridge (HP:0000444) | 1.63725937 |
METTL4 
