

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of retinoic acid receptor signaling pathway (GO:0048387) | 5.67051431 |
| 2 | establishment of integrated proviral latency (GO:0075713) | 5.10005245 |
| 3 | regulation of retinoic acid receptor signaling pathway (GO:0048385) | 4.98588905 |
| 4 | mitotic metaphase plate congression (GO:0007080) | 4.93429509 |
| 5 | CENP-A containing nucleosome assembly (GO:0034080) | 4.91944395 |
| 6 | chromatin remodeling at centromere (GO:0031055) | 4.85902782 |
| 7 | protein localization to kinetochore (GO:0034501) | 4.74145873 |
| 8 | ribosome assembly (GO:0042255) | 4.61367088 |
| 9 | protein localization to chromosome, centromeric region (GO:0071459) | 4.42930667 |
| 10 | metaphase plate congression (GO:0051310) | 4.42427464 |
| 11 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.16288140 |
| 12 | histone exchange (GO:0043486) | 4.16183065 |
| 13 | proteasome assembly (GO:0043248) | 4.11056486 |
| 14 | DNA replication-independent nucleosome organization (GO:0034724) | 4.09035376 |
| 15 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.09035376 |
| 16 | mitotic chromosome condensation (GO:0007076) | 4.06133594 |
| 17 | DNA strand elongation (GO:0022616) | 4.02856693 |
| 18 | DNA ligation (GO:0006266) | 3.93175404 |
| 19 | establishment of viral latency (GO:0019043) | 3.89227763 |
| 20 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.87211126 |
| 21 | mitotic sister chromatid cohesion (GO:0007064) | 3.81570233 |
| 22 | DNA replication checkpoint (GO:0000076) | 3.79880309 |
| 23 | mitotic sister chromatid segregation (GO:0000070) | 3.78781342 |
| 24 | establishment of chromosome localization (GO:0051303) | 3.70342478 |
| 25 | regulation of DNA endoreduplication (GO:0032875) | 3.69667004 |
| 26 | DNA unwinding involved in DNA replication (GO:0006268) | 3.68723585 |
| 27 | kinetochore organization (GO:0051383) | 3.67037973 |
| 28 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.62910035 |
| 29 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.60146301 |
| 30 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.60146301 |
| 31 | nuclear pore complex assembly (GO:0051292) | 3.57514760 |
| 32 | sister chromatid segregation (GO:0000819) | 3.57203764 |
| 33 | DNA topological change (GO:0006265) | 3.56160003 |
| 34 | formation of translation preinitiation complex (GO:0001731) | 3.55955554 |
| 35 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.53989624 |
| 36 | DNA damage response, detection of DNA damage (GO:0042769) | 3.51217282 |
| 37 | spindle checkpoint (GO:0031577) | 3.49804447 |
| 38 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.48737765 |
| 39 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.45485863 |
| 40 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.44308916 |
| 41 | mitotic recombination (GO:0006312) | 3.39989904 |
| 42 | regulation of centriole replication (GO:0046599) | 3.36277520 |
| 43 | protein localization to chromosome (GO:0034502) | 3.31565695 |
| 44 | telomere maintenance via recombination (GO:0000722) | 3.29828351 |
| 45 | mitotic spindle checkpoint (GO:0071174) | 3.29678099 |
| 46 | spliceosomal snRNP assembly (GO:0000387) | 3.28823966 |
| 47 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.26473584 |
| 48 | telomere maintenance via telomere lengthening (GO:0010833) | 3.26252459 |
| 49 | kinetochore assembly (GO:0051382) | 3.25961257 |
| 50 | ATP-dependent chromatin remodeling (GO:0043044) | 3.23829435 |
| 51 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.22369454 |
| 52 | non-recombinational repair (GO:0000726) | 3.22369454 |
| 53 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.20363260 |
| 54 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.20363260 |
| 55 | cullin deneddylation (GO:0010388) | 3.18116111 |
| 56 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.17546367 |
| 57 | 7-methylguanosine mRNA capping (GO:0006370) | 3.17488773 |
| 58 | ribosome biogenesis (GO:0042254) | 3.17382304 |
| 59 | DNA replication initiation (GO:0006270) | 3.17240895 |
| 60 | regulation of chromosome segregation (GO:0051983) | 3.16654514 |
| 61 | negative regulation of ligase activity (GO:0051352) | 3.15122658 |
| 62 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.15122658 |
| 63 | regulation of spindle organization (GO:0090224) | 3.11459750 |
| 64 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.11420141 |
| 65 | IMP biosynthetic process (GO:0006188) | 3.08515475 |
| 66 | RNA capping (GO:0036260) | 3.08215252 |
| 67 | 7-methylguanosine RNA capping (GO:0009452) | 3.08215252 |
| 68 | chromosome segregation (GO:0007059) | 3.06654748 |
| 69 | ribosomal large subunit biogenesis (GO:0042273) | 3.06444142 |
| 70 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.05830829 |
| 71 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.05830829 |
| 72 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.05830829 |
| 73 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.05830829 |
| 74 | negative regulation of sister chromatid segregation (GO:0033046) | 3.05830829 |
| 75 | negative regulation of chromosome segregation (GO:0051985) | 3.05445292 |
| 76 | nuclear pore organization (GO:0006999) | 3.05210919 |
| 77 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.03205089 |
| 78 | chromatin assembly or disassembly (GO:0006333) | 3.02556643 |
| 79 | DNA double-strand break processing (GO:0000729) | 3.02203116 |
| 80 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.01392154 |
| 81 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.99466479 |
| 82 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.97123049 |
| 83 | chaperone-mediated protein transport (GO:0072321) | 2.96941032 |
| 84 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.96789278 |
| 85 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.96789278 |
| 86 | rRNA modification (GO:0000154) | 2.93238279 |
| 87 | spindle assembly checkpoint (GO:0071173) | 2.91752706 |
| 88 | postreplication repair (GO:0006301) | 2.90712427 |
| 89 | histone mRNA metabolic process (GO:0008334) | 2.90506164 |
| 90 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.89873270 |
| 91 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.89637229 |
| 92 | mitotic spindle assembly checkpoint (GO:0007094) | 2.89275901 |
| 93 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.88645208 |
| 94 | positive regulation of ligase activity (GO:0051351) | 2.88639423 |
| 95 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.87990764 |
| 96 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 2.87651118 |
| 97 | transcription from mitochondrial promoter (GO:0006390) | 2.86680594 |
| 98 | protein deneddylation (GO:0000338) | 2.86559996 |
| 99 | purine nucleobase biosynthetic process (GO:0009113) | 2.85779751 |
| 100 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.85098896 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.99277250 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.95830930 |
| 3 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.10875390 |
| 4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.98756405 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.92679693 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.73413893 |
| 7 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.65623040 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.52708953 |
| 9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.40717693 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.04030465 |
| 11 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.94583817 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.94206434 |
| 13 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.91260360 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.77386936 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.74121268 |
| 16 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.61338741 |
| 17 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.61055110 |
| 18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.52422057 |
| 19 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.51735322 |
| 20 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.51315487 |
| 21 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.46105544 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.39110912 |
| 23 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.38230300 |
| 24 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.37971238 |
| 25 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.33121271 |
| 26 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.31843360 |
| 27 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.31437111 |
| 28 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.29260180 |
| 29 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.23695760 |
| 30 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.18471632 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.15716208 |
| 32 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.08345712 |
| 33 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.03839130 |
| 34 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 2.02311800 |
| 35 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.00594837 |
| 36 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.00310500 |
| 37 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.99939129 |
| 38 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.99190262 |
| 39 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.97952000 |
| 40 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.97898519 |
| 41 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.97257586 |
| 42 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.94377684 |
| 43 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.88396252 |
| 44 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.75341425 |
| 45 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.75188887 |
| 46 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.74937429 |
| 47 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.67564186 |
| 48 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.62762482 |
| 49 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.60781095 |
| 50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.59877891 |
| 51 | * PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.53237291 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.51614611 |
| 53 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.46882643 |
| 54 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.40898714 |
| 55 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.38529496 |
| 56 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.28701398 |
| 57 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.27904588 |
| 58 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.27600927 |
| 59 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.27449525 |
| 60 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.23310882 |
| 61 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.22492402 |
| 62 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.22479398 |
| 63 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.21897211 |
| 64 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.18417519 |
| 65 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.14730578 |
| 66 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.14644148 |
| 67 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.14509257 |
| 68 | EWS_26573619_Chip-Seq_HEK293_Human | 1.13586000 |
| 69 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.12631565 |
| 70 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.11386443 |
| 71 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.06954067 |
| 72 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.04639531 |
| 73 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.03777584 |
| 74 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.96713376 |
| 75 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.96021278 |
| 76 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.94304940 |
| 77 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92264960 |
| 78 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.88555010 |
| 79 | FUS_26573619_Chip-Seq_HEK293_Human | 0.85348020 |
| 80 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.85247619 |
| 81 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.82475343 |
| 82 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.82294711 |
| 83 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.82279069 |
| 84 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.81030782 |
| 85 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.78359131 |
| 86 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.77464922 |
| 87 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.76333851 |
| 88 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.76215480 |
| 89 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.75718175 |
| 90 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.75635672 |
| 91 | * CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.74879290 |
| 92 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.74878789 |
| 93 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.74849718 |
| 94 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.74306705 |
| 95 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.72579741 |
| 96 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.70522950 |
| 97 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.70166503 |
| 98 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.69567485 |
| 99 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.69550996 |
| 100 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.68152207 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 5.23574750 |
| 2 | MP0010094_abnormal_chromosome_stability | 4.65691008 |
| 3 | MP0004957_abnormal_blastocyst_morpholog | 4.41445207 |
| 4 | MP0008058_abnormal_DNA_repair | 4.29621525 |
| 5 | MP0003111_abnormal_nucleus_morphology | 4.12586011 |
| 6 | MP0003077_abnormal_cell_cycle | 3.43701527 |
| 7 | MP0008932_abnormal_embryonic_tissue | 3.16939110 |
| 8 | MP0008057_abnormal_DNA_replication | 2.80414752 |
| 9 | MP0008007_abnormal_cellular_replicative | 2.75433866 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.70813255 |
| 11 | MP0003718_maternal_effect | 2.65273577 |
| 12 | MP0006292_abnormal_olfactory_placode | 2.33187421 |
| 13 | MP0001730_embryonic_growth_arrest | 2.13034907 |
| 14 | MP0003806_abnormal_nucleotide_metabolis | 2.06581121 |
| 15 | MP0001293_anophthalmia | 2.03553309 |
| 16 | MP0003315_abnormal_perineum_morphology | 1.92651934 |
| 17 | MP0003941_abnormal_skin_development | 1.84208060 |
| 18 | MP0000350_abnormal_cell_proliferation | 1.76834572 |
| 19 | MP0003186_abnormal_redox_activity | 1.65767848 |
| 20 | MP0001697_abnormal_embryo_size | 1.62966588 |
| 21 | MP0005380_embryogenesis_phenotype | 1.61212266 |
| 22 | MP0001672_abnormal_embryogenesis/_devel | 1.61212266 |
| 23 | MP0003121_genomic_imprinting | 1.59876534 |
| 24 | MP0003890_abnormal_embryonic-extraembry | 1.59413250 |
| 25 | MP0008789_abnormal_olfactory_epithelium | 1.54617083 |
| 26 | MP0002085_abnormal_embryonic_tissue | 1.53809470 |
| 27 | MP0002210_abnormal_sex_determination | 1.53218036 |
| 28 | MP0002084_abnormal_developmental_patter | 1.48849631 |
| 29 | MP0010030_abnormal_orbit_morphology | 1.47861595 |
| 30 | MP0009697_abnormal_copulation | 1.43794260 |
| 31 | MP0003786_premature_aging | 1.43380581 |
| 32 | MP0003984_embryonic_growth_retardation | 1.37907710 |
| 33 | MP0003567_abnormal_fetal_cardiomyocyte | 1.37188215 |
| 34 | MP0002102_abnormal_ear_morphology | 1.37053014 |
| 35 | MP0002080_prenatal_lethality | 1.36304203 |
| 36 | MP0003011_delayed_dark_adaptation | 1.33599843 |
| 37 | MP0005394_taste/olfaction_phenotype | 1.33426183 |
| 38 | MP0005499_abnormal_olfactory_system | 1.33426183 |
| 39 | MP0003937_abnormal_limbs/digits/tail_de | 1.32659227 |
| 40 | MP0002088_abnormal_embryonic_growth/wei | 1.31748039 |
| 41 | MP0001929_abnormal_gametogenesis | 1.30159495 |
| 42 | MP0010307_abnormal_tumor_latency | 1.29645140 |
| 43 | MP0000313_abnormal_cell_death | 1.26358684 |
| 44 | MP0001286_abnormal_eye_development | 1.23859521 |
| 45 | MP0000358_abnormal_cell_content/ | 1.23391283 |
| 46 | MP0006035_abnormal_mitochondrial_morpho | 1.22263141 |
| 47 | MP0006072_abnormal_retinal_apoptosis | 1.20983037 |
| 48 | MP0004197_abnormal_fetal_growth/weight/ | 1.19654567 |
| 49 | MP0002697_abnormal_eye_size | 1.19574917 |
| 50 | MP0001145_abnormal_male_reproductive | 1.18078737 |
| 51 | MP0001529_abnormal_vocalization | 1.17903470 |
| 52 | MP0005248_abnormal_Harderian_gland | 1.17665000 |
| 53 | MP0009672_abnormal_birth_weight | 1.16425350 |
| 54 | MP0000653_abnormal_sex_gland | 1.11919355 |
| 55 | MP0005084_abnormal_gallbladder_morpholo | 1.09706680 |
| 56 | MP0002233_abnormal_nose_morphology | 1.09466345 |
| 57 | MP0003221_abnormal_cardiomyocyte_apopto | 1.09236716 |
| 58 | MP0002938_white_spotting | 1.08325448 |
| 59 | MP0000372_irregular_coat_pigmentation | 1.08245068 |
| 60 | MP0002234_abnormal_pharynx_morphology | 1.08201137 |
| 61 | MP0001346_abnormal_lacrimal_gland | 1.07195025 |
| 62 | MP0003755_abnormal_palate_morphology | 1.02242207 |
| 63 | MP0003123_paternal_imprinting | 1.01874837 |
| 64 | MP0000647_abnormal_sebaceous_gland | 1.01565841 |
| 65 | MP0006036_abnormal_mitochondrial_physio | 0.97533425 |
| 66 | MP0005391_vision/eye_phenotype | 0.95348665 |
| 67 | MP0008995_early_reproductive_senescence | 0.94340819 |
| 68 | MP0005253_abnormal_eye_physiology | 0.93441016 |
| 69 | MP0003861_abnormal_nervous_system | 0.91805570 |
| 70 | MP0001119_abnormal_female_reproductive | 0.91574742 |
| 71 | MP0002751_abnormal_autonomic_nervous | 0.90932061 |
| 72 | MP0002086_abnormal_extraembryonic_tissu | 0.90821867 |
| 73 | MP0005501_abnormal_skin_physiology | 0.90009692 |
| 74 | MP0000049_abnormal_middle_ear | 0.88825610 |
| 75 | MP0002092_abnormal_eye_morphology | 0.88702532 |
| 76 | MP0003119_abnormal_digestive_system | 0.88699544 |
| 77 | MP0001727_abnormal_embryo_implantation | 0.88270481 |
| 78 | MP0002877_abnormal_melanocyte_morpholog | 0.85379171 |
| 79 | MP0002111_abnormal_tail_morphology | 0.85163823 |
| 80 | MP0003122_maternal_imprinting | 0.82724038 |
| 81 | MP0001188_hyperpigmentation | 0.82596215 |
| 82 | MP0001764_abnormal_homeostasis | 0.81597308 |
| 83 | MP0000579_abnormal_nail_morphology | 0.80886413 |
| 84 | MP0002160_abnormal_reproductive_system | 0.79276577 |
| 85 | MP0009703_decreased_birth_body | 0.79078498 |
| 86 | MP0000778_abnormal_nervous_system | 0.78505779 |
| 87 | MP0003385_abnormal_body_wall | 0.77738373 |
| 88 | MP0003698_abnormal_male_reproductive | 0.77549656 |
| 89 | MP0005187_abnormal_penis_morphology | 0.75767515 |
| 90 | MP0005395_other_phenotype | 0.74606765 |
| 91 | MP0006276_abnormal_autonomic_nervous | 0.73032788 |
| 92 | MP0002161_abnormal_fertility/fecundity | 0.72483217 |
| 93 | MP0002638_abnormal_pupillary_reflex | 0.71923092 |
| 94 | MP0002736_abnormal_nociception_after | 0.70892122 |
| 95 | MP0003880_abnormal_central_pattern | 0.69654953 |
| 96 | MP0000490_abnormal_crypts_of | 0.69637622 |
| 97 | MP0003699_abnormal_female_reproductive | 0.69314377 |
| 98 | MP0003935_abnormal_craniofacial_develop | 0.68105454 |
| 99 | MP0005384_cellular_phenotype | 0.65522407 |
| 100 | MP0005197_abnormal_uvea_morphology | 0.61956005 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Volvulus (HP:0002580) | 3.50914559 |
| 2 | Abnormality of the labia minora (HP:0012880) | 3.47153423 |
| 3 | Chromsome breakage (HP:0040012) | 3.39946811 |
| 4 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.35963981 |
| 5 | Abnormal lung lobation (HP:0002101) | 3.34380011 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.19097422 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.13060172 |
| 8 | Abnormality of chromosome stability (HP:0003220) | 2.99635110 |
| 9 | Meckel diverticulum (HP:0002245) | 2.95125583 |
| 10 | Birth length less than 3rd percentile (HP:0003561) | 2.92875716 |
| 11 | Cortical dysplasia (HP:0002539) | 2.89437562 |
| 12 | Acute encephalopathy (HP:0006846) | 2.87995432 |
| 13 | Multiple enchondromatosis (HP:0005701) | 2.87340786 |
| 14 | Microvesicular hepatic steatosis (HP:0001414) | 2.83302054 |
| 15 | Abnormality of the ileum (HP:0001549) | 2.72121891 |
| 16 | Increased serum pyruvate (HP:0003542) | 2.71384770 |
| 17 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.68001776 |
| 18 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.65219972 |
| 19 | Abnormality of the preputium (HP:0100587) | 2.62539816 |
| 20 | Increased CSF lactate (HP:0002490) | 2.58214273 |
| 21 | Horseshoe kidney (HP:0000085) | 2.52390045 |
| 22 | Abnormality of glycolysis (HP:0004366) | 2.51904426 |
| 23 | Embryonal renal neoplasm (HP:0011794) | 2.51638022 |
| 24 | Shoulder girdle muscle weakness (HP:0003547) | 2.49649779 |
| 25 | Increased hepatocellular lipid droplets (HP:0006565) | 2.46563264 |
| 26 | Oligodactyly (hands) (HP:0001180) | 2.44230555 |
| 27 | Mitochondrial inheritance (HP:0001427) | 2.43015430 |
| 28 | Progressive macrocephaly (HP:0004481) | 2.35719623 |
| 29 | Abnormality of the anterior horn cell (HP:0006802) | 2.34588355 |
| 30 | Degeneration of anterior horn cells (HP:0002398) | 2.34588355 |
| 31 | Medulloblastoma (HP:0002885) | 2.34370817 |
| 32 | Increased nuchal translucency (HP:0010880) | 2.32898815 |
| 33 | Small intestinal stenosis (HP:0012848) | 2.31034252 |
| 34 | Duodenal stenosis (HP:0100867) | 2.31034252 |
| 35 | Carpal bone hypoplasia (HP:0001498) | 2.30893946 |
| 36 | Supernumerary spleens (HP:0009799) | 2.28988045 |
| 37 | Cerebral edema (HP:0002181) | 2.27031678 |
| 38 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.26676079 |
| 39 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.26676079 |
| 40 | Hypoplastic pelvis (HP:0008839) | 2.23886701 |
| 41 | Reticulocytopenia (HP:0001896) | 2.22108130 |
| 42 | Colon cancer (HP:0003003) | 2.19119314 |
| 43 | Abnormality of the septum pellucidum (HP:0007375) | 2.18311197 |
| 44 | Lipid accumulation in hepatocytes (HP:0006561) | 2.13574305 |
| 45 | Agnosia (HP:0010524) | 2.13078470 |
| 46 | Increased serum lactate (HP:0002151) | 2.12557574 |
| 47 | Hyperglycinemia (HP:0002154) | 2.07944204 |
| 48 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.06954756 |
| 49 | Aplastic anemia (HP:0001915) | 2.03020884 |
| 50 | Abnormality of the duodenum (HP:0002246) | 2.02620895 |
| 51 | Hepatocellular necrosis (HP:0001404) | 2.02536560 |
| 52 | Oligodactyly (HP:0012165) | 1.99629324 |
| 53 | Gonadotropin excess (HP:0000837) | 1.98586456 |
| 54 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.97091122 |
| 55 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.97091122 |
| 56 | Septo-optic dysplasia (HP:0100842) | 1.96298836 |
| 57 | Methylmalonic acidemia (HP:0002912) | 1.95865408 |
| 58 | Renal Fanconi syndrome (HP:0001994) | 1.95841141 |
| 59 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.94504665 |
| 60 | Sloping forehead (HP:0000340) | 1.93753589 |
| 61 | Type I transferrin isoform profile (HP:0003642) | 1.93393954 |
| 62 | Hepatic necrosis (HP:0002605) | 1.91316497 |
| 63 | Rhabdomyosarcoma (HP:0002859) | 1.90591156 |
| 64 | Median cleft lip (HP:0000161) | 1.88310300 |
| 65 | Neoplasm of the adrenal gland (HP:0100631) | 1.86274707 |
| 66 | Ependymoma (HP:0002888) | 1.86183599 |
| 67 | Myelodysplasia (HP:0002863) | 1.85184033 |
| 68 | Abnormality of the corticospinal tract (HP:0002492) | 1.84728088 |
| 69 | Abnormal hair whorl (HP:0010721) | 1.84073848 |
| 70 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.83975055 |
| 71 | Absent septum pellucidum (HP:0001331) | 1.83083458 |
| 72 | Increased intramyocellular lipid droplets (HP:0012240) | 1.81669343 |
| 73 | Proximal placement of thumb (HP:0009623) | 1.79966183 |
| 74 | Stenosis of the external auditory canal (HP:0000402) | 1.78401592 |
| 75 | Oral leukoplakia (HP:0002745) | 1.78133916 |
| 76 | Squamous cell carcinoma (HP:0002860) | 1.77227579 |
| 77 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.75517034 |
| 78 | Lactic acidosis (HP:0003128) | 1.75461614 |
| 79 | Premature ovarian failure (HP:0008209) | 1.75330973 |
| 80 | High anterior hairline (HP:0009890) | 1.73726487 |
| 81 | Short tibia (HP:0005736) | 1.73693072 |
| 82 | Leukodystrophy (HP:0002415) | 1.71060874 |
| 83 | Macrocytic anemia (HP:0001972) | 1.70796851 |
| 84 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.69967193 |
| 85 | Amniotic constriction ring (HP:0009775) | 1.69162124 |
| 86 | Abnormality of placental membranes (HP:0011409) | 1.69162124 |
| 87 | Absent radius (HP:0003974) | 1.68609807 |
| 88 | Abnormal number of erythroid precursors (HP:0012131) | 1.68440541 |
| 89 | Abnormal number of incisors (HP:0011064) | 1.68374415 |
| 90 | Ectopic kidney (HP:0000086) | 1.67764345 |
| 91 | Triphalangeal thumb (HP:0001199) | 1.67581865 |
| 92 | Hemivertebrae (HP:0002937) | 1.67529403 |
| 93 | Reduced antithrombin III activity (HP:0001976) | 1.67260213 |
| 94 | Hypoplasia of the uterus (HP:0000013) | 1.65538378 |
| 95 | Neoplasm of the colon (HP:0100273) | 1.65151318 |
| 96 | Postnatal microcephaly (HP:0005484) | 1.64857589 |
| 97 | Abnormality of serum amino acid levels (HP:0003112) | 1.64271583 |
| 98 | Spastic diplegia (HP:0001264) | 1.64224812 |
| 99 | Abnormality of methionine metabolism (HP:0010901) | 1.63948818 |
| 100 | Facial cleft (HP:0002006) | 1.63476289 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDC7 | 3.90087867 |
| 2 | BUB1 | 3.85584177 |
| 3 | SRPK1 | 3.73833233 |
| 4 | TTK | 3.18244770 |
| 5 | NEK1 | 3.07553215 |
| 6 | EIF2AK3 | 3.06148991 |
| 7 | TSSK6 | 2.89483806 |
| 8 | EIF2AK1 | 2.54115094 |
| 9 | PLK4 | 2.51513462 |
| 10 | PLK3 | 2.38177646 |
| 11 | MST4 | 2.34567183 |
| 12 | PBK | 2.24511703 |
| 13 | MKNK1 | 2.10460905 |
| 14 | WEE1 | 2.10347458 |
| 15 | STK16 | 2.09527420 |
| 16 | TNIK | 1.96137093 |
| 17 | PLK1 | 1.93680041 |
| 18 | VRK2 | 1.91983504 |
| 19 | TRIM28 | 1.75421741 |
| 20 | NME1 | 1.73510960 |
| 21 | MKNK2 | 1.63974069 |
| 22 | PLK2 | 1.60112635 |
| 23 | NEK2 | 1.51541722 |
| 24 | BCR | 1.47845887 |
| 25 | VRK1 | 1.45438799 |
| 26 | PNCK | 1.40343748 |
| 27 | BRSK2 | 1.39691380 |
| 28 | AURKB | 1.31542761 |
| 29 | WNK3 | 1.29997143 |
| 30 | ATR | 1.29625313 |
| 31 | KDR | 1.17845730 |
| 32 | NUAK1 | 1.15595827 |
| 33 | ZAK | 1.12790054 |
| 34 | BRD4 | 1.12555068 |
| 35 | RPS6KA4 | 1.08374206 |
| 36 | CHEK1 | 1.07599963 |
| 37 | CCNB1 | 1.06882619 |
| 38 | PDK2 | 1.03222892 |
| 39 | CHEK2 | 1.01540259 |
| 40 | BRSK1 | 1.00086088 |
| 41 | AURKA | 0.98953084 |
| 42 | CLK1 | 0.97201001 |
| 43 | BMPR1B | 0.95105500 |
| 44 | TAF1 | 0.93685760 |
| 45 | CDK12 | 0.91855971 |
| 46 | CDK7 | 0.91746249 |
| 47 | CDK3 | 0.87894954 |
| 48 | ATM | 0.85684146 |
| 49 | PASK | 0.82552631 |
| 50 | STK4 | 0.80743012 |
| 51 | STK24 | 0.78984799 |
| 52 | NTRK1 | 0.76803749 |
| 53 | ALK | 0.76282211 |
| 54 | MAP3K4 | 0.76200173 |
| 55 | DYRK2 | 0.72990009 |
| 56 | STK38L | 0.72255480 |
| 57 | LATS2 | 0.71623899 |
| 58 | EIF2AK2 | 0.70652501 |
| 59 | * CSNK2A2 | 0.69604284 |
| 60 | CSNK2A1 | 0.69437437 |
| 61 | CDK2 | 0.68571935 |
| 62 | CDK11A | 0.68236525 |
| 63 | SCYL2 | 0.67937839 |
| 64 | CDK18 | 0.66906252 |
| 65 | CDK19 | 0.66060505 |
| 66 | CSNK1G2 | 0.65815104 |
| 67 | CDK14 | 0.64748531 |
| 68 | CDK15 | 0.63998299 |
| 69 | NEK9 | 0.63127246 |
| 70 | CDK1 | 0.62379597 |
| 71 | MAP3K9 | 0.61517336 |
| 72 | RAF1 | 0.61068327 |
| 73 | ERBB4 | 0.60197916 |
| 74 | MAP3K8 | 0.60118896 |
| 75 | * CSNK1E | 0.60037236 |
| 76 | ERBB3 | 0.58413672 |
| 77 | CSNK1G1 | 0.58066098 |
| 78 | NME2 | 0.55470331 |
| 79 | EPHB2 | 0.55238310 |
| 80 | STK10 | 0.54323246 |
| 81 | DYRK3 | 0.53804526 |
| 82 | CSNK1G3 | 0.53172746 |
| 83 | BRAF | 0.50323870 |
| 84 | STK3 | 0.49231820 |
| 85 | CDK8 | 0.49091539 |
| 86 | CDK4 | 0.48663590 |
| 87 | KSR1 | 0.48623395 |
| 88 | MAP2K7 | 0.48306665 |
| 89 | PRKCI | 0.48060199 |
| 90 | CDK9 | 0.47207552 |
| 91 | ARAF | 0.41039215 |
| 92 | YES1 | 0.39858039 |
| 93 | RPS6KB2 | 0.38416938 |
| 94 | PRKDC | 0.37006205 |
| 95 | AKT2 | 0.36832307 |
| 96 | MAP4K2 | 0.32102590 |
| 97 | TGFBR1 | 0.31531610 |
| 98 | CSNK1A1L | 0.31235064 |
| 99 | MINK1 | 0.29518224 |
| 100 | RPS6KA5 | 0.27517517 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mismatch repair_Homo sapiens_hsa03430 | 3.95097615 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 3.90978757 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.69092744 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.64965761 |
| 5 | Spliceosome_Homo sapiens_hsa03040 | 3.07756791 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.91206212 |
| 7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.85492341 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.85041876 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.79278248 |
| 10 | RNA transport_Homo sapiens_hsa03013 | 2.70626789 |
| 11 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.67104676 |
| 12 | Ribosome_Homo sapiens_hsa03010 | 2.54057070 |
| 13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.53164375 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 2.51418673 |
| 15 | Base excision repair_Homo sapiens_hsa03410 | 2.50507304 |
| 16 | Cell cycle_Homo sapiens_hsa04110 | 2.46130011 |
| 17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.17936776 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 2.05551718 |
| 19 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.96721818 |
| 20 | Parkinsons disease_Homo sapiens_hsa05012 | 1.85119070 |
| 21 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.82155409 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.71832183 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.69086307 |
| 24 | Huntingtons disease_Homo sapiens_hsa05016 | 1.54396331 |
| 25 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.49523005 |
| 26 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.45295760 |
| 27 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.34467189 |
| 28 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.31206698 |
| 29 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.28551846 |
| 30 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.27821647 |
| 31 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.27590970 |
| 32 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.27241620 |
| 33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.25351572 |
| 34 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.21004555 |
| 35 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.20937509 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.19722825 |
| 37 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.19312046 |
| 38 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.07561003 |
| 39 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.06503554 |
| 40 | Carbon metabolism_Homo sapiens_hsa01200 | 1.02853537 |
| 41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.02853032 |
| 42 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.00158095 |
| 43 | Alzheimers disease_Homo sapiens_hsa05010 | 0.96178422 |
| 44 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.92587525 |
| 45 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.89022464 |
| 46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.87866345 |
| 47 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.79133507 |
| 48 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.78319099 |
| 49 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.75342324 |
| 50 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.73201891 |
| 51 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.72087486 |
| 52 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.71821032 |
| 53 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.69525246 |
| 54 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.68915776 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.66830884 |
| 56 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.63021702 |
| 57 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.57827348 |
| 58 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.51344265 |
| 59 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.48259601 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.48180696 |
| 61 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.46319724 |
| 62 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.45563637 |
| 63 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.45212858 |
| 64 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.44959117 |
| 65 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.42063950 |
| 66 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.41878597 |
| 67 | Peroxisome_Homo sapiens_hsa04146 | 0.41573936 |
| 68 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.40476919 |
| 69 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.39887204 |
| 70 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.39043168 |
| 71 | Adherens junction_Homo sapiens_hsa04520 | 0.38581606 |
| 72 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.36942760 |
| 73 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.36132183 |
| 74 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.34005091 |
| 75 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.30833899 |
| 76 | Thyroid cancer_Homo sapiens_hsa05216 | 0.30712867 |
| 77 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.30385611 |
| 78 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.29123910 |
| 79 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.26792060 |
| 80 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.25694276 |
| 81 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.22212132 |
| 82 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.21896756 |
| 83 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.20893878 |
| 84 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.20686308 |
| 85 | Phototransduction_Homo sapiens_hsa04744 | 0.20409141 |
| 86 | Shigellosis_Homo sapiens_hsa05131 | 0.18550062 |
| 87 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.17607883 |
| 88 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.17202674 |
| 89 | Tight junction_Homo sapiens_hsa04530 | 0.17183331 |
| 90 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.13653874 |
| 91 | Legionellosis_Homo sapiens_hsa05134 | 0.11877553 |
| 92 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.09082514 |
| 93 | Lysine degradation_Homo sapiens_hsa00310 | 0.08742803 |
| 94 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.06072150 |
| 95 | HTLV-I infection_Homo sapiens_hsa05166 | 0.05394283 |
| 96 | Colorectal cancer_Homo sapiens_hsa05210 | 0.05324537 |
| 97 | Alcoholism_Homo sapiens_hsa05034 | 0.04187854 |
| 98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.03531918 |
| 99 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.03419248 |
| 100 | Galactose metabolism_Homo sapiens_hsa00052 | 0.02294722 |

