Rank | Gene Set | Z-score |
---|---|---|
1 | sarcomere organization (GO:0045214) | 5.82358142 |
2 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 5.66166221 |
3 | cardiac myofibril assembly (GO:0055003) | 5.46386140 |
4 | tricarboxylic acid cycle (GO:0006099) | 5.34658263 |
5 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 5.28163492 |
6 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 5.24653211 |
7 | carnitine shuttle (GO:0006853) | 4.99301698 |
8 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 4.94212322 |
9 | plasma membrane repair (GO:0001778) | 4.93978806 |
10 | myofibril assembly (GO:0030239) | 4.90669858 |
11 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 4.88785715 |
12 | cardiac muscle contraction (GO:0060048) | 4.69730127 |
13 | actin-myosin filament sliding (GO:0033275) | 4.65431977 |
14 | muscle filament sliding (GO:0030049) | 4.65431977 |
15 | fatty acid transmembrane transport (GO:1902001) | 4.54403828 |
16 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 4.50334385 |
17 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 4.49003878 |
18 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 4.43749925 |
19 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 4.43509991 |
20 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 4.29370766 |
21 | ventricular cardiac muscle cell action potential (GO:0086005) | 4.12219251 |
22 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 4.11829610 |
23 | cell communication involved in cardiac conduction (GO:0086065) | 4.11780016 |
24 | regulation of skeletal muscle contraction (GO:0014819) | 4.10574270 |
25 | focal adhesion assembly (GO:0048041) | 4.07262414 |
26 | cell-substrate adherens junction assembly (GO:0007045) | 4.07262414 |
27 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 4.04532014 |
28 | regulation of actin filament-based movement (GO:1903115) | 4.02591805 |
29 | skeletal muscle contraction (GO:0003009) | 4.02133984 |
30 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 4.01242891 |
31 | cell communication by electrical coupling (GO:0010644) | 3.99512663 |
32 | carnitine transmembrane transport (GO:1902603) | 3.94638824 |
33 | 2-oxoglutarate metabolic process (GO:0006103) | 3.89005839 |
34 | NADH metabolic process (GO:0006734) | 3.87421320 |
35 | regulation of membrane repolarization (GO:0060306) | 3.86277228 |
36 | striated muscle contraction (GO:0006941) | 3.84391761 |
37 | adherens junction assembly (GO:0034333) | 3.83609528 |
38 | cardiac muscle cell development (GO:0055013) | 3.81549153 |
39 | regulation of cell communication by electrical coupling (GO:0010649) | 3.78586787 |
40 | regulation of cofactor metabolic process (GO:0051193) | 3.78426405 |
41 | regulation of coenzyme metabolic process (GO:0051196) | 3.78426405 |
42 | actin-mediated cell contraction (GO:0070252) | 3.78403730 |
43 | actomyosin structure organization (GO:0031032) | 3.77794662 |
44 | cell-substrate junction assembly (GO:0007044) | 3.75023630 |
45 | regulation of relaxation of muscle (GO:1901077) | 3.74892138 |
46 | amino-acid betaine transport (GO:0015838) | 3.71271022 |
47 | carnitine transport (GO:0015879) | 3.71271022 |
48 | cardiac muscle hypertrophy (GO:0003300) | 3.69590075 |
49 | lysine catabolic process (GO:0006554) | 3.63461452 |
50 | lysine metabolic process (GO:0006553) | 3.63461452 |
51 | striated muscle hypertrophy (GO:0014897) | 3.54698846 |
52 | aspartate family amino acid catabolic process (GO:0009068) | 3.53318840 |
53 | cardiac cell development (GO:0055006) | 3.53171515 |
54 | adult heart development (GO:0007512) | 3.50924038 |
55 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.47041534 |
56 | regulation of sequestering of triglyceride (GO:0010889) | 3.46139340 |
57 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.44674533 |
58 | regulation of striated muscle contraction (GO:0006942) | 3.42467132 |
59 | regulation of fatty acid oxidation (GO:0046320) | 3.41084171 |
60 | succinate metabolic process (GO:0006105) | 3.39587127 |
61 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 3.39532552 |
62 | regulation of sarcomere organization (GO:0060297) | 3.36939786 |
63 | heart trabecula formation (GO:0060347) | 3.33063561 |
64 | regulation of the force of heart contraction (GO:0002026) | 3.32202569 |
65 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.31110691 |
66 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.26898215 |
67 | fatty acid beta-oxidation (GO:0006635) | 3.25945514 |
68 | desmosome organization (GO:0002934) | 3.25018565 |
69 | oxaloacetate metabolic process (GO:0006107) | 3.24464650 |
70 | muscle contraction (GO:0006936) | 3.23443044 |
71 | protein localization to endosome (GO:0036010) | 3.23012138 |
72 | Golgi transport vesicle coating (GO:0048200) | 3.22307878 |
73 | COPI coating of Golgi vesicle (GO:0048205) | 3.22307878 |
74 | regulation of calcium ion transmembrane transport (GO:1903169) | 3.18679743 |
75 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 3.18679743 |
76 | skeletal muscle adaptation (GO:0043501) | 3.18316992 |
77 | positive regulation of myotube differentiation (GO:0010831) | 3.16339799 |
78 | striated muscle adaptation (GO:0014888) | 3.16004134 |
79 | negative regulation of potassium ion transport (GO:0043267) | 3.15659995 |
80 | regulation of early endosome to late endosome transport (GO:2000641) | 3.14699600 |
81 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.12768188 |
82 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 3.12482555 |
83 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.11951231 |
84 | creatine metabolic process (GO:0006600) | 3.10906456 |
85 | cardiac muscle cell action potential (GO:0086001) | 3.08628965 |
86 | muscle hypertrophy (GO:0014896) | 3.07848913 |
87 | regulation of sulfur metabolic process (GO:0042762) | 3.06640667 |
88 | negative regulation of necroptotic process (GO:0060546) | 3.06090909 |
89 | response to inactivity (GO:0014854) | 3.04447415 |
90 | epithelial cell-cell adhesion (GO:0090136) | 3.01839665 |
91 | cellular response to epinephrine stimulus (GO:0071872) | 3.01392774 |
92 | cardiac conduction (GO:0061337) | 2.98819775 |
93 | regulation of heart rate (GO:0002027) | 2.96971593 |
94 | muscle tissue morphogenesis (GO:0060415) | 2.96014608 |
95 | actin filament-based movement (GO:0030048) | 2.95780186 |
96 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.95761849 |
97 | hemidesmosome assembly (GO:0031581) | 2.95423369 |
98 | cardiac muscle adaptation (GO:0014887) | 2.95252966 |
99 | cardiac muscle hypertrophy in response to stress (GO:0014898) | 2.95252966 |
100 | muscle hypertrophy in response to stress (GO:0003299) | 2.95252966 |
101 | glycogen catabolic process (GO:0005980) | 2.93237269 |
102 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.93070756 |
103 | gluconeogenesis (GO:0006094) | 2.92971346 |
104 | regulation of cardiac muscle contraction (GO:0055117) | 2.92900391 |
105 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.92874018 |
106 | tricarboxylic acid metabolic process (GO:0072350) | 2.92409931 |
107 | relaxation of cardiac muscle (GO:0055119) | 2.92396556 |
108 | regulation of synapse structural plasticity (GO:0051823) | 2.91623196 |
109 | sodium ion export (GO:0071436) | 2.90668067 |
110 | muscle system process (GO:0003012) | 2.90600946 |
111 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.89617526 |
112 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.89603988 |
113 | regulation of cardiac muscle cell contraction (GO:0086004) | 2.88741788 |
114 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.87975546 |
115 | cellular ketone body metabolic process (GO:0046950) | 2.87016825 |
116 | positive regulation of cation channel activity (GO:2001259) | 2.86029312 |
117 | fatty acid catabolic process (GO:0009062) | 2.83929337 |
118 | activation of protein kinase A activity (GO:0034199) | 2.83500242 |
119 | detection of calcium ion (GO:0005513) | 2.82175971 |
120 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.80422133 |
121 | acetyl-CoA metabolic process (GO:0006084) | 2.80036269 |
122 | quaternary ammonium group transport (GO:0015697) | 2.79768697 |
123 | response to muscle activity (GO:0014850) | 2.79376127 |
124 | positive regulation of fatty acid oxidation (GO:0046321) | 2.79198137 |
125 | glucan catabolic process (GO:0009251) | 2.78040315 |
126 | regulation of heart contraction (GO:0008016) | 2.76596680 |
127 | stress fiber assembly (GO:0043149) | 2.75415696 |
128 | potassium ion import (GO:0010107) | 2.74300509 |
129 | fatty acid oxidation (GO:0019395) | 2.74244311 |
130 | positive regulation of receptor recycling (GO:0001921) | 2.71655568 |
131 | hexose biosynthetic process (GO:0019319) | 2.70528982 |
132 | glycolytic process (GO:0006096) | 2.67665096 |
133 | response to epinephrine (GO:0071871) | 2.62078869 |
134 | muscle adaptation (GO:0043500) | 2.60735090 |
135 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.58476396 |
136 | negative regulation of myotube differentiation (GO:0010832) | 2.57393379 |
137 | heart contraction (GO:0060047) | 2.54676788 |
138 | heart process (GO:0003015) | 2.54676788 |
139 | monosaccharide biosynthetic process (GO:0046364) | 2.51790687 |
140 | negative regulation of cell size (GO:0045792) | 2.51244886 |
141 | regulation of cardioblast differentiation (GO:0051890) | 2.49695091 |
142 | barbed-end actin filament capping (GO:0051016) | 2.49636595 |
143 | cellular polysaccharide catabolic process (GO:0044247) | 2.46140330 |
144 | fructose metabolic process (GO:0006000) | 2.46066300 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.95413745 |
2 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.51472324 |
3 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.42334955 |
4 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.28165836 |
5 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.20521935 |
6 | * ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.94000659 |
7 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.55520395 |
8 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.51773590 |
9 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.20864447 |
10 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.19503538 |
11 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.18793397 |
12 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 2.10682433 |
13 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 2.08272189 |
14 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.07686336 |
15 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 2.06768571 |
16 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 2.06768571 |
17 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.01908682 |
18 | MYC_22102868_ChIP-Seq_BL_Human | 1.99799675 |
19 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.99517857 |
20 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.98649235 |
21 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.98528296 |
22 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.96951307 |
23 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.96067504 |
24 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.87506056 |
25 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.86319510 |
26 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.84343481 |
27 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.84078575 |
28 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.82026287 |
29 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.80657745 |
30 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.79326664 |
31 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.77862466 |
32 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.77554383 |
33 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.74257410 |
34 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.71497421 |
35 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.71179851 |
36 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.70348073 |
37 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.68098493 |
38 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.67760981 |
39 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.65201218 |
40 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.62647523 |
41 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.62549088 |
42 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.62549088 |
43 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.60331522 |
44 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.56726121 |
45 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.56165897 |
46 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.50067356 |
47 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.49440730 |
48 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.47126342 |
49 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.45807147 |
50 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.45463255 |
51 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.44842304 |
52 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.42664936 |
53 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.39774533 |
54 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.39112232 |
55 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.38250132 |
56 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.37267964 |
57 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.33772022 |
58 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.33570230 |
59 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.32710660 |
60 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.32499050 |
61 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.31631506 |
62 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.30202557 |
63 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.29754809 |
64 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.28205508 |
65 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.27765316 |
66 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.26846961 |
67 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.25985380 |
68 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.25634703 |
69 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.25309752 |
70 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.25084412 |
71 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.24354796 |
72 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.24101827 |
73 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.22992526 |
74 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.22901023 |
75 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.22865833 |
76 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.22429484 |
77 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.21894440 |
78 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.21894239 |
79 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 1.20773851 |
80 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.20643122 |
81 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.20534372 |
82 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.19561426 |
83 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.19378616 |
84 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.18452389 |
85 | KDM2B_26808549_Chip-Seq_K562_Human | 1.17614113 |
86 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 1.16893645 |
87 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.16846319 |
88 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.15895723 |
89 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.15564525 |
90 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.15259500 |
91 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.15075372 |
92 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.14784477 |
93 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.14673757 |
94 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.13596388 |
95 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.13440213 |
96 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.12868629 |
97 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.12833114 |
98 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.12714228 |
99 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.11988682 |
100 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.11423545 |
101 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.11391058 |
102 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.11281151 |
103 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.10273911 |
104 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.09426382 |
105 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.07519484 |
106 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.07485538 |
107 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.07191548 |
108 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.06812125 |
109 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.06527204 |
110 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.06470680 |
111 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.05185792 |
112 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.04834571 |
113 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.04824148 |
114 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.04582997 |
115 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.02928374 |
116 | * MAF_26560356_Chip-Seq_TH1_Human | 1.01921937 |
117 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01454351 |
118 | * SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.01037859 |
119 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.00131846 |
120 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.00067380 |
121 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.99575603 |
122 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.97720692 |
123 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.97003258 |
124 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.95169896 |
125 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.94335682 |
126 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.94119987 |
127 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.93141001 |
128 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.92519518 |
129 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.92277287 |
130 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.91760006 |
131 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.90786194 |
132 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.90781321 |
133 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90424949 |
134 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.89529998 |
135 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.89513662 |
136 | * TP63_22573176_ChIP-Seq_HFKS_Human | 0.89371260 |
137 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.89168227 |
138 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.87085215 |
139 | AR_19668381_ChIP-Seq_PC3_Human | 0.86815845 |
140 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.86301268 |
141 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.85942405 |
142 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.85762093 |
143 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.85010611 |
144 | GATA1_19941826_ChIP-Seq_K562_Human | 0.84849314 |
145 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.84006132 |
146 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.83486557 |
147 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.78846876 |
148 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.78444913 |
149 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.78353095 |
150 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.78116735 |
151 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.78080965 |
152 | P68_20966046_ChIP-Seq_HELA_Human | 0.78010328 |
153 | * CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.77787041 |
154 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.77322738 |
155 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 0.76818939 |
156 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.76648581 |
157 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.75774704 |
158 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.75015815 |
159 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.74860334 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002837_dystrophic_cardiac_calcinosis | 6.03304726 |
2 | MP0003646_muscle_fatigue | 4.86632980 |
3 | MP0000751_myopathy | 4.70386673 |
4 | MP0004084_abnormal_cardiac_muscle | 4.28326380 |
5 | MP0004215_abnormal_myocardial_fiber | 3.84657727 |
6 | MP0005451_abnormal_body_composition | 3.82051683 |
7 | MP0004036_abnormal_muscle_relaxation | 3.61375584 |
8 | MP0000749_muscle_degeneration | 3.31958956 |
9 | MP0005330_cardiomyopathy | 3.09316437 |
10 | MP0004130_abnormal_muscle_cell | 3.01371247 |
11 | MP0004087_abnormal_muscle_fiber | 2.68630133 |
12 | MP0002972_abnormal_cardiac_muscle | 2.48798253 |
13 | MP0004145_abnormal_muscle_electrophysio | 2.45992674 |
14 | MP0005620_abnormal_muscle_contractility | 2.43324269 |
15 | MP0003137_abnormal_impulse_conducting | 2.33227402 |
16 | MP0008775_abnormal_heart_ventricle | 2.30265273 |
17 | MP0003566_abnormal_cell_adhesion | 2.18765837 |
18 | MP0002269_muscular_atrophy | 2.17097607 |
19 | MP0002106_abnormal_muscle_physiology | 2.15667558 |
20 | MP0000750_abnormal_muscle_regeneration | 2.10541192 |
21 | MP0000747_muscle_weakness | 2.08989415 |
22 | MP0001544_abnormal_cardiovascular_syste | 2.04131933 |
23 | MP0005385_cardiovascular_system_phenoty | 2.04131933 |
24 | MP0004859_abnormal_synaptic_plasticity | 2.01137239 |
25 | MP0004484_altered_response_of | 1.99396344 |
26 | MP0002877_abnormal_melanocyte_morpholog | 1.98496457 |
27 | MP0006138_congestive_heart_failure | 1.93836697 |
28 | MP0005670_abnormal_white_adipose | 1.93529371 |
29 | MP0010630_abnormal_cardiac_muscle | 1.93198510 |
30 | MP0004085_abnormal_heartbeat | 1.87962428 |
31 | MP0000759_abnormal_skeletal_muscle | 1.84605870 |
32 | MP0005409_darkened_coat_color | 1.80282705 |
33 | MP0004233_abnormal_muscle_weight | 1.77265253 |
34 | MP0005369_muscle_phenotype | 1.76240345 |
35 | MP0005666_abnormal_adipose_tissue | 1.72973234 |
36 | MP0000733_abnormal_muscle_development | 1.59902110 |
37 | MP0010234_abnormal_vibrissa_follicle | 1.59860261 |
38 | MP0003221_abnormal_cardiomyocyte_apopto | 1.49388407 |
39 | MP0002822_catalepsy | 1.49264781 |
40 | MP0002909_abnormal_adrenal_gland | 1.48045989 |
41 | * MP0006036_abnormal_mitochondrial_physio | 1.47561255 |
42 | MP0008260_abnormal_autophagy | 1.43726053 |
43 | MP0004510_myositis | 1.37101182 |
44 | MP0001661_extended_life_span | 1.36378616 |
45 | MP0008438_abnormal_cutaneous_collagen | 1.36130922 |
46 | MP0005085_abnormal_gallbladder_physiolo | 1.32432331 |
47 | MP0005360_urolithiasis | 1.31725263 |
48 | MP0000013_abnormal_adipose_tissue | 1.31635172 |
49 | MP0002332_abnormal_exercise_endurance | 1.31608057 |
50 | MP0002139_abnormal_hepatobiliary_system | 1.31553962 |
51 | MP0005375_adipose_tissue_phenotype | 1.26046609 |
52 | MP0000579_abnormal_nail_morphology | 1.23717220 |
53 | MP0001849_ear_inflammation | 1.23271568 |
54 | MP0009780_abnormal_chondrocyte_physiolo | 1.21977195 |
55 | MP0003453_abnormal_keratinocyte_physiol | 1.21541107 |
56 | MP0004185_abnormal_adipocyte_glucose | 1.20199171 |
57 | MP0003191_abnormal_cellular_cholesterol | 1.17661093 |
58 | MP0003091_abnormal_cell_migration | 1.17653182 |
59 | MP0008961_abnormal_basal_metabolism | 1.17330541 |
60 | MP0004270_analgesia | 1.16862813 |
61 | MP0003828_pulmonary_edema | 1.16708521 |
62 | MP0003635_abnormal_synaptic_transmissio | 1.15690686 |
63 | MP0005058_abnormal_lysosome_morphology | 1.13866526 |
64 | MP0004272_abnormal_basement_membrane | 1.13331171 |
65 | MP0005076_abnormal_cell_differentiation | 1.11856416 |
66 | MP0005365_abnormal_bile_salt | 1.10208835 |
67 | MP0010352_gastrointestinal_tract_polyps | 1.09847418 |
68 | MP0003329_amyloid_beta_deposits | 1.09711220 |
69 | MP0003705_abnormal_hypodermis_morpholog | 1.07428292 |
70 | MP0005535_abnormal_body_temperature | 1.06370904 |
71 | MP0010329_abnormal_lipoprotein_level | 1.05056163 |
72 | MP0002971_abnormal_brown_adipose | 1.03961779 |
73 | MP0002234_abnormal_pharynx_morphology | 1.02147830 |
74 | MP0002127_abnormal_cardiovascular_syste | 1.01318797 |
75 | MP0002796_impaired_skin_barrier | 0.99770906 |
76 | MP0004043_abnormal_pH_regulation | 0.97973780 |
77 | MP0002118_abnormal_lipid_homeostasis | 0.93029180 |
78 | MP0000003_abnormal_adipose_tissue | 0.90697572 |
79 | MP0000230_abnormal_systemic_arterial | 0.90450956 |
80 | MP0002078_abnormal_glucose_homeostasis | 0.86853687 |
81 | MP0010368_abnormal_lymphatic_system | 0.86376652 |
82 | MP0009745_abnormal_behavioral_response | 0.85248922 |
83 | MP0003656_abnormal_erythrocyte_physiolo | 0.84863958 |
84 | MP0002108_abnormal_muscle_morphology | 0.84145930 |
85 | MP0002063_abnormal_learning/memory/cond | 0.83732852 |
86 | MP0004858_abnormal_nervous_system | 0.82920235 |
87 | MP0005275_abnormal_skin_tensile | 0.81162905 |
88 | MP0000467_abnormal_esophagus_morphology | 0.80717063 |
89 | MP0005332_abnormal_amino_acid | 0.80245707 |
90 | MP0004924_abnormal_behavior | 0.79867348 |
91 | MP0005386_behavior/neurological_phenoty | 0.79867348 |
92 | MP0000678_abnormal_parathyroid_gland | 0.79061010 |
93 | MP0001730_embryonic_growth_arrest | 0.78954635 |
94 | MP0009046_muscle_twitch | 0.78936877 |
95 | MP0001958_emphysema | 0.78854283 |
96 | MP0003950_abnormal_plasma_membrane | 0.78330066 |
97 | MP0002060_abnormal_skin_morphology | 0.78314212 |
98 | MP0003806_abnormal_nucleotide_metabolis | 0.78150141 |
99 | MP0003045_fibrosis | 0.78098682 |
100 | MP0002064_seizures | 0.77980503 |
101 | MP0008875_abnormal_xenobiotic_pharmacok | 0.77206914 |
102 | MP0003300_gastrointestinal_ulcer | 0.77130646 |
103 | MP0005266_abnormal_metabolism | 0.76518641 |
104 | MP0005165_increased_susceptibility_to | 0.76461380 |
105 | MP0000266_abnormal_heart_morphology | 0.76226849 |
106 | MP0001348_abnormal_lacrimal_gland | 0.75797408 |
107 | MP0005023_abnormal_wound_healing | 0.75751668 |
108 | MP0005319_abnormal_enzyme/_coenzyme | 0.75532211 |
109 | MP0008569_lethality_at_weaning | 0.75462421 |
110 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.75173414 |
111 | MP0003252_abnormal_bile_duct | 0.74140209 |
112 | MP0005083_abnormal_biliary_tract | 0.73996493 |
113 | MP0003879_abnormal_hair_cell | 0.72086746 |
114 | MP0009840_abnormal_foam_cell | 0.71226394 |
115 | MP0002272_abnormal_nervous_system | 0.69557792 |
116 | * MP0006035_abnormal_mitochondrial_morpho | 0.69501458 |
117 | MP0003880_abnormal_central_pattern | 0.69315346 |
118 | MP0009672_abnormal_birth_weight | 0.68726106 |
119 | MP0003279_aneurysm | 0.68446002 |
120 | MP0000343_altered_response_to | 0.68174954 |
121 | MP0005623_abnormal_meninges_morphology | 0.68084602 |
122 | MP0000762_abnormal_tongue_morphology | 0.66399480 |
123 | MP0001440_abnormal_grooming_behavior | 0.65990364 |
124 | MP0003195_calcinosis | 0.64629873 |
125 | MP0005334_abnormal_fat_pad | 0.63934781 |
126 | MP0008874_decreased_physiological_sensi | 0.62908455 |
127 | MP0002128_abnormal_blood_circulation | 0.62332744 |
128 | MP0002896_abnormal_bone_mineralization | 0.62300331 |
129 | MP0005501_abnormal_skin_physiology | 0.61784972 |
130 | MP0000858_altered_metastatic_potential | 0.61009317 |
131 | MP0005187_abnormal_penis_morphology | 0.60928705 |
132 | MP0001915_intracranial_hemorrhage | 0.60570535 |
133 | MP0008004_abnormal_stomach_pH | 0.59906647 |
134 | MP0002735_abnormal_chemical_nociception | 0.59834657 |
135 | MP0003633_abnormal_nervous_system | 0.59709646 |
136 | MP0000767_abnormal_smooth_muscle | 0.58174988 |
137 | MP0004947_skin_inflammation | 0.58004473 |
138 | MP0003984_embryonic_growth_retardation | 0.57873329 |
139 | MP0005448_abnormal_energy_balance | 0.57806037 |
140 | MP0002572_abnormal_emotion/affect_behav | 0.55625284 |
141 | MP0002734_abnormal_mechanical_nocicepti | 0.53232203 |
142 | MP0005167_abnormal_blood-brain_barrier | 0.53229735 |
143 | MP0003075_altered_response_to | 0.52849604 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sudden death (HP:0001699) | 6.52216323 |
2 | Exercise-induced myalgia (HP:0003738) | 5.89654237 |
3 | Exercise-induced muscle cramps (HP:0003710) | 5.25128467 |
4 | Calf muscle hypertrophy (HP:0008981) | 5.20676416 |
5 | Ventricular tachycardia (HP:0004756) | 4.92459269 |
6 | Muscle hypertrophy of the lower extremities (HP:0008968) | 4.90583744 |
7 | Myoglobinuria (HP:0002913) | 4.88698874 |
8 | Muscle fiber splitting (HP:0003555) | 4.78461296 |
9 | Atrial fibrillation (HP:0005110) | 4.61715067 |
10 | Hyporeflexia of lower limbs (HP:0002600) | 4.60853259 |
11 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 4.56818362 |
12 | Primary atrial arrhythmia (HP:0001692) | 4.35263355 |
13 | Abnormality of the calf musculature (HP:0001430) | 4.33751017 |
14 | Bundle branch block (HP:0011710) | 4.23071594 |
15 | Supraventricular tachycardia (HP:0004755) | 4.15831818 |
16 | Supraventricular arrhythmia (HP:0005115) | 4.08196218 |
17 | Syncope (HP:0001279) | 4.01226079 |
18 | Lipoatrophy (HP:0100578) | 3.93027648 |
19 | Right ventricular cardiomyopathy (HP:0011663) | 3.89721216 |
20 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.89248332 |
21 | Subaortic stenosis (HP:0001682) | 3.89248332 |
22 | Difficulty running (HP:0009046) | 3.79143007 |
23 | Myopathic facies (HP:0002058) | 3.69581926 |
24 | EMG: myopathic abnormalities (HP:0003458) | 3.68555602 |
25 | Prolonged QT interval (HP:0001657) | 3.67555064 |
26 | Palpitations (HP:0001962) | 3.65279751 |
27 | Asymmetric septal hypertrophy (HP:0001670) | 3.63233314 |
28 | Ventricular fibrillation (HP:0001663) | 3.57848106 |
29 | Increased connective tissue (HP:0009025) | 3.56821716 |
30 | Ventricular arrhythmia (HP:0004308) | 3.48454738 |
31 | Rhabdomyolysis (HP:0003201) | 3.46733685 |
32 | Myotonia (HP:0002486) | 3.42304816 |
33 | Heart block (HP:0012722) | 3.41095245 |
34 | Atrioventricular block (HP:0001678) | 3.35192013 |
35 | Dilated cardiomyopathy (HP:0001644) | 3.32510845 |
36 | Abnormal atrioventricular conduction (HP:0005150) | 3.21130675 |
37 | Ketoacidosis (HP:0001993) | 3.20729626 |
38 | Type 1 muscle fiber predominance (HP:0003803) | 2.91941271 |
39 | Difficulty climbing stairs (HP:0003551) | 2.90823694 |
40 | Abnormal EKG (HP:0003115) | 2.83635408 |
41 | Muscle stiffness (HP:0003552) | 2.81159774 |
42 | Ketosis (HP:0001946) | 2.80351130 |
43 | Increased variability in muscle fiber diameter (HP:0003557) | 2.76136856 |
44 | Round ear (HP:0100830) | 2.75681507 |
45 | Muscle fiber inclusion bodies (HP:0100299) | 2.72119309 |
46 | Hypoglycemic coma (HP:0001325) | 2.69945645 |
47 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.62539644 |
48 | Pheochromocytoma (HP:0002666) | 2.62329502 |
49 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.58555504 |
50 | Spinal rigidity (HP:0003306) | 2.54798762 |
51 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.50485912 |
52 | Ulnar deviation of the wrist (HP:0003049) | 2.38242487 |
53 | Left ventricular hypertrophy (HP:0001712) | 2.36887581 |
54 | Progressive muscle weakness (HP:0003323) | 2.32258064 |
55 | * Abnormality of the foot musculature (HP:0001436) | 2.29870212 |
56 | Distal arthrogryposis (HP:0005684) | 2.29407253 |
57 | Limb-girdle muscle atrophy (HP:0003797) | 2.26984858 |
58 | * Foot dorsiflexor weakness (HP:0009027) | 2.25419237 |
59 | Neuroendocrine neoplasm (HP:0100634) | 2.23680345 |
60 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.23585217 |
61 | Dicarboxylic aciduria (HP:0003215) | 2.23585217 |
62 | EMG: neuropathic changes (HP:0003445) | 2.23158289 |
63 | Hyperammonemia (HP:0001987) | 2.21255269 |
64 | Ragged-red muscle fibers (HP:0003200) | 2.16949828 |
65 | Bulbar palsy (HP:0001283) | 2.16570731 |
66 | Achilles tendon contracture (HP:0001771) | 2.16341938 |
67 | Conjunctival hamartoma (HP:0100780) | 2.14592935 |
68 | Hyperglycinuria (HP:0003108) | 2.10917846 |
69 | Hepatic necrosis (HP:0002605) | 2.10789709 |
70 | Neck muscle weakness (HP:0000467) | 2.08842191 |
71 | Cholelithiasis (HP:0001081) | 2.08836498 |
72 | Increased muscle lipid content (HP:0009058) | 2.07084103 |
73 | Hamartoma of the eye (HP:0010568) | 2.06136403 |
74 | Calcaneovalgus deformity (HP:0001848) | 2.04606890 |
75 | Nemaline bodies (HP:0003798) | 2.03154071 |
76 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.01175870 |
77 | Abnormality of the Achilles tendon (HP:0005109) | 2.00352684 |
78 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.98499455 |
79 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.98182517 |
80 | Abnormality of the salivary glands (HP:0010286) | 1.97256808 |
81 | Cholecystitis (HP:0001082) | 1.96941186 |
82 | Abnormal gallbladder physiology (HP:0012438) | 1.96941186 |
83 | Areflexia of lower limbs (HP:0002522) | 1.96912981 |
84 | Distal lower limb muscle weakness (HP:0009053) | 1.94204818 |
85 | Cerebral edema (HP:0002181) | 1.94126977 |
86 | Protrusio acetabuli (HP:0003179) | 1.92184042 |
87 | Hypoalphalipoproteinemia (HP:0003233) | 1.89608071 |
88 | Facial diplegia (HP:0001349) | 1.88814908 |
89 | Distal lower limb amyotrophy (HP:0008944) | 1.88574323 |
90 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.87272256 |
91 | Abnormality of glycine metabolism (HP:0010895) | 1.87272256 |
92 | Lower limb amyotrophy (HP:0007210) | 1.86835019 |
93 | Abnormal gallbladder morphology (HP:0012437) | 1.86768171 |
94 | Testicular atrophy (HP:0000029) | 1.86646967 |
95 | Cerebral aneurysm (HP:0004944) | 1.86579760 |
96 | Sudden cardiac death (HP:0001645) | 1.86120302 |
97 | Abnormality of the tricuspid valve (HP:0001702) | 1.85868895 |
98 | Myokymia (HP:0002411) | 1.85340157 |
99 | Palmoplantar keratoderma (HP:0000982) | 1.84763911 |
100 | Abnormality of the calcaneus (HP:0008364) | 1.84677806 |
101 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.83746459 |
102 | Rimmed vacuoles (HP:0003805) | 1.82748328 |
103 | Acute encephalopathy (HP:0006846) | 1.81737139 |
104 | Athetosis (HP:0002305) | 1.81645059 |
105 | Hyperacusis (HP:0010780) | 1.80056537 |
106 | Rapidly progressive (HP:0003678) | 1.79328996 |
107 | Acute necrotizing encephalopathy (HP:0006965) | 1.76130938 |
108 | Back pain (HP:0003418) | 1.75875322 |
109 | Lymphangioma (HP:0100764) | 1.75623809 |
110 | Frequent falls (HP:0002359) | 1.74672265 |
111 | Muscular dystrophy (HP:0003560) | 1.74622757 |
112 | Gowers sign (HP:0003391) | 1.74272833 |
113 | Congestive heart failure (HP:0001635) | 1.73648084 |
114 | Distal upper limb amyotrophy (HP:0007149) | 1.73571598 |
115 | Upper limb amyotrophy (HP:0009129) | 1.73571598 |
116 | Obstructive sleep apnea (HP:0002870) | 1.73078038 |
117 | Skin nodule (HP:0200036) | 1.72371552 |
118 | Polycythemia (HP:0001901) | 1.71924305 |
119 | Gout (HP:0001997) | 1.70682704 |
120 | Slender build (HP:0001533) | 1.69772731 |
121 | Scapular winging (HP:0003691) | 1.69748653 |
122 | Premature rupture of membranes (HP:0001788) | 1.69679565 |
123 | Generalized muscle weakness (HP:0003324) | 1.69446474 |
124 | Deformed tarsal bones (HP:0008119) | 1.67186875 |
125 | Broad metatarsal (HP:0001783) | 1.67001060 |
126 | Reticulocytosis (HP:0001923) | 1.66205241 |
127 | Neoplasm of the adrenal gland (HP:0100631) | 1.65552706 |
128 | Oligomenorrhea (HP:0000876) | 1.64545107 |
129 | Visual hallucinations (HP:0002367) | 1.63555362 |
130 | Hepatocellular necrosis (HP:0001404) | 1.63408109 |
131 | Generalized amyotrophy (HP:0003700) | 1.63094359 |
132 | Ankyloglossia (HP:0010296) | 1.62272848 |
133 | Aneurysm (HP:0002617) | 1.61533965 |
134 | Fatigue (HP:0012378) | 1.59457294 |
135 | Resting tremor (HP:0002322) | 1.57668440 |
136 | Progressive external ophthalmoplegia (HP:0000590) | 1.56541489 |
137 | Advanced eruption of teeth (HP:0006288) | 1.54686307 |
138 | Abnormality of the shoulder girdle musculature (HP:0001435) | 1.48852308 |
139 | Cerebral inclusion bodies (HP:0100314) | 1.47411103 |
140 | Osteolytic defects of the hand bones (HP:0009699) | 1.47251606 |
141 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.47251606 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 4.25572607 |
2 | PHKG1 | 3.69183782 |
3 | PHKG2 | 3.69183782 |
4 | PDK3 | 3.44627923 |
5 | PDK4 | 3.44627923 |
6 | LMTK2 | 3.28410453 |
7 | OBSCN | 3.18073254 |
8 | TRIB3 | 3.06326957 |
9 | PRPF4B | 2.86730767 |
10 | EEF2K | 2.81983642 |
11 | PKN2 | 2.61244438 |
12 | BCKDK | 2.27936405 |
13 | DMPK | 2.21032162 |
14 | MYLK | 2.20845230 |
15 | NEK1 | 2.15951942 |
16 | PINK1 | 1.99070927 |
17 | PDK2 | 1.98292182 |
18 | SMG1 | 1.98237171 |
19 | CDK12 | 1.97377517 |
20 | PRKD3 | 1.68447364 |
21 | IRAK3 | 1.53281979 |
22 | RIPK1 | 1.41591251 |
23 | PIK3CA | 1.39671475 |
24 | PAK3 | 1.39302540 |
25 | MAP2K4 | 1.38632152 |
26 | STK38 | 1.35601754 |
27 | PAK6 | 1.33235798 |
28 | MUSK | 1.32645719 |
29 | MAP3K4 | 1.31948823 |
30 | MAP3K9 | 1.30101864 |
31 | KSR2 | 1.28351393 |
32 | EPHA4 | 1.25667036 |
33 | MAP3K7 | 1.25070274 |
34 | NTRK3 | 1.21793800 |
35 | MST1R | 1.21404151 |
36 | MAP3K6 | 1.20742333 |
37 | TIE1 | 1.16639912 |
38 | RIPK4 | 1.11913816 |
39 | ARAF | 1.08260303 |
40 | DAPK2 | 1.07173788 |
41 | TAOK2 | 1.04024165 |
42 | MAP3K13 | 1.03497608 |
43 | WNK4 | 1.02382950 |
44 | MAPK12 | 1.00436865 |
45 | MARK1 | 0.99243804 |
46 | NEK9 | 0.98269304 |
47 | TRPM7 | 0.98132976 |
48 | MTOR | 0.96799778 |
49 | PRKD1 | 0.96269087 |
50 | SCYL2 | 0.95886329 |
51 | PTK2B | 0.94423425 |
52 | CAMKK1 | 0.94011837 |
53 | MINK1 | 0.93589050 |
54 | CAMK2D | 0.93570037 |
55 | PRKAA1 | 0.93514459 |
56 | STK24 | 0.91423303 |
57 | TAOK1 | 0.90018177 |
58 | EPHA2 | 0.89472088 |
59 | LATS2 | 0.87786563 |
60 | PDGFRA | 0.87733484 |
61 | SIK1 | 0.87272863 |
62 | CAMK1G | 0.84626347 |
63 | ICK | 0.83655645 |
64 | MOS | 0.83572885 |
65 | RET | 0.82877748 |
66 | CDC42BPA | 0.82355343 |
67 | PTK2 | 0.81887988 |
68 | MAP3K10 | 0.80346705 |
69 | RAF1 | 0.79119891 |
70 | ROCK1 | 0.78816412 |
71 | PRKCH | 0.77182468 |
72 | PDPK1 | 0.76055433 |
73 | PIK3CG | 0.75625878 |
74 | MET | 0.74650911 |
75 | PRKAA2 | 0.74563528 |
76 | INSRR | 0.74153655 |
77 | PDK1 | 0.71868347 |
78 | CAMK1 | 0.71143264 |
79 | CAMK1D | 0.70107867 |
80 | BMX | 0.69994863 |
81 | CAMK2A | 0.69852434 |
82 | MAPK11 | 0.68223847 |
83 | CAMK4 | 0.68220500 |
84 | GRK7 | 0.67869216 |
85 | SGK3 | 0.66085666 |
86 | NTRK1 | 0.64839525 |
87 | ILK | 0.64802639 |
88 | MAP3K5 | 0.64663969 |
89 | PAK4 | 0.64416113 |
90 | AKT2 | 0.64213764 |
91 | WNK1 | 0.63372925 |
92 | MAP2K3 | 0.62395031 |
93 | MAPKAPK3 | 0.57576380 |
94 | DAPK3 | 0.57043322 |
95 | NME1 | 0.55619156 |
96 | FER | 0.55395860 |
97 | CDK5 | 0.54111726 |
98 | MAP3K1 | 0.53676300 |
99 | MAP3K8 | 0.53228236 |
100 | PRKACG | 0.52211668 |
101 | RPS6KL1 | 0.51445522 |
102 | RPS6KC1 | 0.51445522 |
103 | CAMK2G | 0.49542712 |
104 | ZAP70 | 0.48919959 |
105 | STK11 | 0.47868981 |
106 | NTRK2 | 0.47290832 |
107 | MAP2K1 | 0.46917073 |
108 | KSR1 | 0.46795062 |
109 | PTK6 | 0.46705828 |
110 | PAK2 | 0.45416310 |
111 | EPHA3 | 0.45135592 |
112 | ERN1 | 0.43923790 |
113 | MAPK10 | 0.43783145 |
114 | BRAF | 0.43478811 |
115 | FGFR3 | 0.43452189 |
116 | SGK494 | 0.43254872 |
117 | SGK223 | 0.43254872 |
118 | PRKACB | 0.42050027 |
119 | PKN1 | 0.41953490 |
120 | STK4 | 0.41806524 |
121 | ROCK2 | 0.41322181 |
122 | TESK1 | 0.41181886 |
123 | SGK2 | 0.39229744 |
124 | MAPK4 | 0.39212087 |
125 | FGFR4 | 0.38967752 |
126 | SGK1 | 0.38246714 |
127 | MAPK7 | 0.38190087 |
128 | GRK5 | 0.38095363 |
129 | RPS6KA3 | 0.37880677 |
130 | PRKD2 | 0.37864061 |
131 | RPS6KA2 | 0.37819495 |
132 | MAP3K11 | 0.36924616 |
133 | PRKG2 | 0.36840792 |
134 | RPS6KB2 | 0.36706117 |
135 | PRKACA | 0.36404938 |
136 | PRKCE | 0.36081126 |
137 | MAP2K6 | 0.35904914 |
138 | CAMK2B | 0.35413920 |
139 | ALK | 0.35315552 |
140 | CAMKK2 | 0.32045493 |
141 | MAP3K2 | 0.30219233 |
142 | MAP3K3 | 0.30109797 |
143 | EPHB1 | 0.29654150 |
144 | MARK2 | 0.29359406 |
145 | PRKCG | 0.28548217 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 4.40287641 |
2 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.51500955 |
3 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.37133992 |
4 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.88115852 |
5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.65342607 |
6 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.64220027 |
7 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.32718224 |
8 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.20494354 |
9 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.17058630 |
10 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.12139289 |
11 | Carbon metabolism_Homo sapiens_hsa01200 | 2.01428104 |
12 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.83348295 |
13 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.79698031 |
14 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.77880405 |
15 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.71059921 |
16 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.69403569 |
17 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.65715677 |
18 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.61565688 |
19 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.59438707 |
20 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.50778526 |
21 | Parkinsons disease_Homo sapiens_hsa05012 | 1.42454924 |
22 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.39647155 |
23 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.38494992 |
24 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.26942262 |
25 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.26577534 |
26 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.25068907 |
27 | Prion diseases_Homo sapiens_hsa05020 | 1.24740498 |
28 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.23892632 |
29 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.22651291 |
30 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.19584423 |
31 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.19336878 |
32 | Endometrial cancer_Homo sapiens_hsa05213 | 1.17451634 |
33 | Adherens junction_Homo sapiens_hsa04520 | 1.16306146 |
34 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.16262865 |
35 | Alzheimers disease_Homo sapiens_hsa05010 | 1.15540457 |
36 | Glioma_Homo sapiens_hsa05214 | 1.14094103 |
37 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.11189149 |
38 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.10973172 |
39 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.10843437 |
40 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.09625781 |
41 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.08126702 |
42 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.08090217 |
43 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.08040040 |
44 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.04217145 |
45 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.04020296 |
46 | Bladder cancer_Homo sapiens_hsa05219 | 1.02398904 |
47 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.01274763 |
48 | Circadian entrainment_Homo sapiens_hsa04713 | 1.01133949 |
49 | Thyroid cancer_Homo sapiens_hsa05216 | 1.01083128 |
50 | Amoebiasis_Homo sapiens_hsa05146 | 0.99515184 |
51 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.99423920 |
52 | Insulin resistance_Homo sapiens_hsa04931 | 0.98096548 |
53 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.97391047 |
54 | Bile secretion_Homo sapiens_hsa04976 | 0.97017539 |
55 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.96991033 |
56 | Insulin secretion_Homo sapiens_hsa04911 | 0.96281532 |
57 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.95621252 |
58 | Renin secretion_Homo sapiens_hsa04924 | 0.94599060 |
59 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.94571494 |
60 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.93916970 |
61 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.93871653 |
62 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.92843910 |
63 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.92715310 |
64 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.92491693 |
65 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.91587212 |
66 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.91398147 |
67 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.90589175 |
68 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.90284155 |
69 | Olfactory transduction_Homo sapiens_hsa04740 | 0.89988378 |
70 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.86667544 |
71 | GABAergic synapse_Homo sapiens_hsa04727 | 0.82168525 |
72 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.81005855 |
73 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.80776968 |
74 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.79270043 |
75 | Other glycan degradation_Homo sapiens_hsa00511 | 0.78302366 |
76 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.78281619 |
77 | Long-term potentiation_Homo sapiens_hsa04720 | 0.76090101 |
78 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.75934742 |
79 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.75442863 |
80 | Peroxisome_Homo sapiens_hsa04146 | 0.75325918 |
81 | Salivary secretion_Homo sapiens_hsa04970 | 0.75228633 |
82 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.74860424 |
83 | Tight junction_Homo sapiens_hsa04530 | 0.72744809 |
84 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.72724165 |
85 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.72460906 |
86 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.72166455 |
87 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.71425926 |
88 | Huntingtons disease_Homo sapiens_hsa05016 | 0.71407004 |
89 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.70675562 |
90 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.70543497 |
91 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.68550890 |
92 | Morphine addiction_Homo sapiens_hsa05032 | 0.65885376 |
93 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.65708986 |
94 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.64817397 |
95 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.64367211 |
96 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.63532899 |
97 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.63327984 |
98 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.62901936 |
99 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.61848183 |
100 | Lysine degradation_Homo sapiens_hsa00310 | 0.61830934 |
101 | Platelet activation_Homo sapiens_hsa04611 | 0.59985508 |
102 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.59720445 |
103 | Viral myocarditis_Homo sapiens_hsa05416 | 0.59554581 |
104 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.58922239 |
105 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.58627549 |
106 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.57945818 |
107 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.55898040 |
108 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.55025986 |
109 | Nicotine addiction_Homo sapiens_hsa05033 | 0.54787636 |
110 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.54560122 |
111 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.53959763 |
112 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.52985707 |
113 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.51816976 |
114 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.51027164 |
115 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.50886662 |
116 | Endocytosis_Homo sapiens_hsa04144 | 0.50193095 |
117 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.49697543 |
118 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.49590387 |
119 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.49297728 |
120 | Galactose metabolism_Homo sapiens_hsa00052 | 0.47679642 |
121 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.47304105 |
122 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.46242016 |
123 | Melanogenesis_Homo sapiens_hsa04916 | 0.45686127 |
124 | Taste transduction_Homo sapiens_hsa04742 | 0.45480857 |
125 | Gap junction_Homo sapiens_hsa04540 | 0.45461051 |
126 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.44718284 |
127 | Prostate cancer_Homo sapiens_hsa05215 | 0.44548659 |
128 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.44100316 |
129 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.41503698 |
130 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.41346198 |
131 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.41182293 |
132 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.41110518 |
133 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.40813096 |
134 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.38243638 |
135 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.38222143 |
136 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.36442939 |
137 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.36331433 |
138 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.34830045 |
139 | Circadian rhythm_Homo sapiens_hsa04710 | 0.34541221 |
140 | Focal adhesion_Homo sapiens_hsa04510 | 0.34155918 |
141 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.33362967 |
142 | Cocaine addiction_Homo sapiens_hsa05030 | 0.33314092 |
143 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.33259807 |
144 | ABC transporters_Homo sapiens_hsa02010 | 0.32685227 |
145 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.29130204 |